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https://www.readbyqxmd.com/read/28812915/kardiovize-brno-2030-a-prospective-cardiovascular-health-study-in-central-europe-methods-baseline-findings-and-future-directions
#1
Narine K Movsisyan, Manlio Vinciguerra, Francisco Lopez-Jimenez, Šárka Kunzová, Martin Homolka, Jana Jaresova, Renata Cífková, Ondřej Sochor
Background Atherosclerotic cardiovascular disease is highly prevalent in Eastern and Central Europe, where the incidence is the highest in the world. The Kardiovize Brno 2030 study was designed as a prospective cohort study to investigate the complex relationships of cardiovascular disease and outcomes with a range of biological, psychosocial, environmental, behavioral, and economic factors in an urban population of the Czech Republic. Methods We randomly selected a 1% sample of the city of Brno residents aged 25-64 years stratified by sex and age...
January 1, 2017: European Journal of Preventive Cardiology
https://www.readbyqxmd.com/read/28810464/the-buddy-system-a-randomized-controlled-experiment-of-the-benefits-and-costs-of-dieting-in-pairs
#2
Angela C Incollingo Rodriguez, Anthony Rodriguez, Lauren C Callahan, Darby Saxbe, A Janet Tomiyama
A total of 67 pairs of female roommates were randomized into a diet condition: (1) both ate normally; (2) one dieted, the other ate normally; and (3) both dieted. Adherence, weight loss, anxiety, depression, disordered eating symptoms, and stress were measured. Dieters lost more weight than non-dieters, but average loss was <1 pound. Pairs where both dieted reported higher anxiety, depression, and disordered eating than one-dieter pairs. Structural equation models revealed an interrelated network of stress, anxiety, depression, and disordered eating...
June 1, 2017: Journal of Health Psychology
https://www.readbyqxmd.com/read/28808064/obesity-and-aging-diminish-sirt1-mediated-deacetylation-of-sirt3-leading-to-hyperacetylation-and-decreased-activity-and-stability-of-sirt3
#3
Sanghoon Kwon, Sunmi Seok, Peter Yau, Xiaoling Li, Byron Kemper, Jongsook Kim Kemper
Sirtuin 3 (SIRT3) deacetylates and regulates many mitochondrial proteins to maintain health, but its functions are depressed in aging and obesity. The best-studied sirtuin, SIRT1, counteracts aging- and obesity-related diseases by deacetylating many proteins, but whether SIRT1 has a role in deacetylating and altering the function of SIRT3 is unknown. Here we show that SIRT3 is reversibly acetylated in the mitochondria and unexpectedly is a target of SIRT1 deacetylation. SIRT3 is hyperacetylated in aged and obese mice, in which SIRT1 activity is low, and SIRT3 acetylation at K57 inhibits its deacetylase activity and promotes protein degradation...
August 14, 2017: Journal of Biological Chemistry
https://www.readbyqxmd.com/read/28805885/effects-of-steeped-or-fermented-distillers-dried-grains-with-solubles-on-growth-performance-in-weanling-pigs
#4
M Wiseman, B McBride, J Li, D Wey, J Zhu, C F M de Lange
Coproduct feeding value may be improved by enzyme and microbial inoculant treatment in liquid diets. Three experiments were conducted to assess growth performance in newly weaned 20-d-old pigs fed corn- and soybean meal-based diets with untreated, steeped, or partially fermented distillers dried grains with solubles (DDGS) from day of weaning. In Exp. 1, conventionally dry fed diets with untreated DDGS (DDGS) or without DDGS (Control) were fed. In Exp. 2, liquid diets (25% DM [75% moisture]) were fed with enzymes (β-glucanase and xylanase at 67...
August 2017: Journal of Animal Science
https://www.readbyqxmd.com/read/28805567/nutrition-and-nonmotor-symptoms-of-parkinson-s-disease
#5
Laurie K Mischley
To date, no guidelines exist for the screening, evaluation, and management of nutritional status in PD. Dozens of studies demonstrate an association between diet in adulthood with subsequent risk of developing PD. Individuals with PD are at increased risk of malnutrition due to the increased metabolic demands and disease pathophysiology. Risk of malnutrition is further complicated by anosmia, swallowing difficulties, constipation, and drug-nutrient interactions. An emerging body of evidence suggests that the intestinal tract is affected early in the disease, creating therapeutic opportunities for early intervention...
2017: International Review of Neurobiology
https://www.readbyqxmd.com/read/28802861/contrasting-effects-of-vortioxetine-and-paroxetine-on-pineal-gland-biochemistry-in-a-tryptophan-depletion-model-of-depression-in-female-rats
#6
M Franklin, N Hlavacova, Y Li, I Bermudez, A Csanova, C Sanchez, D Jezova
We studied the effects of the multi-modal antidepressant, vortioxetine and the SSRI, paroxetine on pineal melatonin and monoamine synthesis in a sub-chronic tryptophan (TRP) depletion model of depression based on a low TRP diet. Female Sprague-Dawley rats were randomised to groups a) control, b) low TRP diet, c) low TRP diet+paroxetine and d) low TRP diet+vortioxetine. Vortioxetine was administered via the diet (0.76mg/kg of food weight) and paroxetine via drinking water (10mg/kg/day) for 14days. Both drugs resulted in SERT occupancies >90%...
August 9, 2017: Progress in Neuro-psychopharmacology & Biological Psychiatry
https://www.readbyqxmd.com/read/28801940/examining-the-association-between-depression-and-obesity-during-a-weight-management-programme
#7
N R Fuller, J Burns, A Sainsbury, S Horsfield, F da Luz, S Zhang, G Denyer, T P Markovic, I D Caterson
The prevalence of depression in those with obesity is reported to be as high as double that in individuals of normal weight. There is potentially a bi-directional relationship between obesity and depression. Some research has suggested that depression results in weight gain and obesity, and other studies have suggested that those with obesity are more likely to develop depression at a later stage. The aim of this study was to investigate the association of depression symptoms with weight change over a 12-month study...
August 11, 2017: Clinical Obesity
https://www.readbyqxmd.com/read/28801926/internet-delivered-eating-disorder-prevention-a-randomized-controlled-trial-of-dissonance-based-and-cognitive-behavioral-interventions
#8
Taona P Chithambo, Stanley J Huey
OBJECTIVE: The current study evaluated two web-based programs for eating disorder prevention in high-risk, predominantly ethnic minority women. METHOD: Two hundred and seventy-one women with elevated weight concerns were randomized to Internet dissonance-based intervention (DBI-I), Internet cognitive-behavioral intervention (CBI-I), or no intervention (NI). Both interventions consisted of four weekly online sessions. Participants were assessed at pre- and post-intervention...
August 11, 2017: International Journal of Eating Disorders
https://www.readbyqxmd.com/read/28799778/how-important-is-tryptophan-in-human-health
#9
Joanna Kałużna-Czaplińska, Paulina Gątarek, Salvatore Chirumbolo, Max Stanley Chartrand, Geir Bjørklund
Tryptophan (Trp) is an amino acid and an essential component of the human diet. It plays a crucial role in many metabolic functions. Clinicians can use Trp levels in the course of diagnosing various metabolic disorders and the symptoms associated with those diseases. Furthermore, supplementation with this amino acid is considered in the treatment of depression and sleep disorders, mainly due to the Trp relationship with the synthesis of serotonin (5-HT) and melatonin. It is also used in helping to resolve cognitive disorders, anxiety, or neurodegenerative diseases...
August 11, 2017: Critical Reviews in Food Science and Nutrition
https://www.readbyqxmd.com/read/28790808/copd-patients-self-reported-adherence-psychosocial-factors-and-mild-cognitive-impairment-in-pulmonary-rehabilitation
#10
Antonia Pierobon, Elisa Sini Bottelli, Laura Ranzini, Claudio Bruschi, Roberto Maestri, Giorgio Bertolotti, Marinella Sommaruga, Valeria Torlaschi, Simona Callegari, Anna Giardini
In addition to clinical comorbidities, psychological and neuropsychological problems are frequent in COPD and may affect pulmonary rehabilitation delivery and outcome. The aims of the study were to describe a COPD population in a rehabilitative setting as regards the patients depressive symptoms, anxiety, mild cognitive impairment (MCI) and self-reported adherence and to analyze their relationships; to compare the COPD sample MCI scores with normative data; and to investigate which factors might predict adherence to prescribed physical exercise...
2017: International Journal of Chronic Obstructive Pulmonary Disease
https://www.readbyqxmd.com/read/28789727/food-based-diet-quality-score-in-relation-to-depressive-symptoms-in-young-and-middle-aged-japanese-women
#11
Hiroka Sakai, Kentaro Murakami, Satomi Kobayashi, Hitomi Suga, Satoshi Sasaki
Only a few studies have focused on the association between overall diet, rather than intakes of individual nutrients or foods, and depressive symptoms in Japanese. This cross-sectional study examined associations between a diet quality score and depressive symptoms in 3963 young (age 18 years) and 3833 middle-aged (mean age 47·9 (sd 4·2) years) Japanese women. Dietary information was collected using a diet history questionnaire. A previously developed diet quality score was computed mainly based on the Japanese Food Guide Spinning Top...
June 2017: British Journal of Nutrition
https://www.readbyqxmd.com/read/28777971/vegetarian-diets-and-depressive-symptoms-among-men
#12
Joseph R Hibbeln, Kate Northstone, Jonathan Evans, Jean Golding
BACKGROUND: Vegetarian diets are associate with cardiovascular and other health benefits, but little is known about mental health benefits or risks. AIMS: To determine whether self-identification of vegetarian dietary habits is associated with significant depressive symptoms in men. METHOD: Self-report data from 9668 adult male partners of pregnant women in the Avon Longitudinal Study of Parents and Children (ALSPAC) included identification as vegetarian or vegan, dietary frequency data and the Edinburgh Post Natal Depression Scale (EPDS)...
July 28, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28776192/role-of-religious-social-support-in-longitudinal-relationships-between-religiosity-and-health-related-outcomes-in-african-americans
#13
Cheryl L Holt, David L Roth, Jin Huang, Eddie M Clark
This study tested a longitudinal model of religious social support as a potential mediator of the relationship between religious beliefs and behaviors, and multiple health-related outcomes (e.g., depressive symptoms, functioning, diet, alcohol use, cancer screening). A national probability sample of African Americans enrolled in the religion and health in African Americans study completed three waves of telephone interviews over a 5-year period (N = 766). Longitudinal structural equation models indicated that religious behaviors, but not beliefs, predicted the slowing of a modest overall decline in positive religious social support, while negative interactions with congregational members were stable...
August 3, 2017: Journal of Behavioral Medicine
https://www.readbyqxmd.com/read/28763492/pancreatic-atrophy-caused-by-dietary-selenium-deficiency-induces-hypoinsulinemic-hyperglycemia-via-global-down-regulation-of-selenoprotein-encoding-genes-in-broilers
#14
Jingyang Xu, Longqiong Wang, Jiayong Tang, Gang Jia, Guangmang Liu, Xiaoling Chen, Jingyi Cai, Haiying Shang, Hua Zhao
This study was envisaged to comprehensively profile genes in selected tissues along with a few biochemical indicators and integrate resulting information with dietary selenium (Se) deficiency symptoms in broilers. A total of 120 one-day-old Cobb male broilers were equally divided into two groups and fed a Se deficient corn-soybean-based basal diet supplemented with 0.3 mg/kg sodium selenite (Control, Se adequate) or without selenite (Se deficiency) for five weeks. Effects of Se deficiency on mRNA abundance of twenty-three selenoprotein encoding genes and seventeen insulin signaling related genes were studied at day 35 in pancreas, liver and muscle along with plasma biochemical constituents and enzyme activities...
2017: PloS One
https://www.readbyqxmd.com/read/28762751/associations-between-alcohol-consumption-and-cardio-metabolic-risk-factors-in-young-adults
#15
Duc Du, Raimondo Bruno, Terry Dwyer, Alison Venn, Seana Gall
Introduction The benefits of alcohol consumption for cardiovascular and metabolic health may have been overstated due to inappropriate comparisons with abstainers and inadequate control for confounding factors including physical activity and mental health. We examined alcohol consumption and cardio-metabolic health in a cohort of young Australian adults overcoming these limitations. Methods Cross-sectional data of a cohort of 2200 participants (age range 25-36 years) from the 2004-06 Childhood Determinants of Adult Health were used...
January 1, 2017: European Journal of Preventive Cardiology
https://www.readbyqxmd.com/read/28754386/sex-specific-differences-in-the-association-between-childhood-adversity-and-cardiovascular-disease-in-adulthood-evidence-from-a-national-cohort-study
#16
Yasmin Garad, Katerina Maximova, Nathalie MacKinnon, Jennifer J McGrath, Anita L Kozyrskyj, Ian Colman
BACKGROUND: Childhood adversity increases the risk for cardiovascular disease (CVD) in adulthood. Previously proposed mechanisms suggest that the association is mediated by stress reactivity-known to be higher in women-and is aggravated by adult stress, but this has not yet been confirmed. Therefore, we investigated sex differences to better understand possible pathways from childhood adversity to CVD. METHODS: The National Population Health Survey, a 15-year cohort study of Canadians aged 18-49 years at baseline was used...
August 2017: Canadian Journal of Cardiology
https://www.readbyqxmd.com/read/28751637/sugar-intake-from-sweet-food-and-beverages-common-mental-disorder-and-depression-prospective-findings-from-the-whitehall-ii-study
#17
Anika Knüppel, Martin J Shipley, Clare H Llewellyn, Eric J Brunner
Intake of sweet food, beverages and added sugars has been linked with depressive symptoms in several populations. Aim of this study was to investigate systematically cross-sectional and prospective associations between sweet food/beverage intake, common mental disorder (CMD) and depression and to examine the role of reverse causation (influence of mood on intake) as potential explanation for the observed linkage. We analysed repeated measures (23,245 person-observations) from the Whitehall II study using random effects regression...
July 27, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28751192/evidence-of-an-inverse-correlation-between-serotonergic-activity-and-spreading-depression-propagation-in-the-rat-cortex
#18
Rubem Carlos Araújo Guedes, Maria das Graças Rodrigues Araújo, Taciana Cristovam Verçosa, Francisca Martins Bion, Andrea Lima de Sá, Antônio Pereira, Ricardo Abadie-Guedes
Various neurological and psychiatric diseases lead to alterations in cortical serotonergic activity as one of their underlying processes. However, the electrophysiological implication of changes in serotonergic activity remains a matter of investigation. In this study, we investigated whether brain serotonergic activity influences the excitability-related phenomenon known as cortical spreading depression (CSD). CSD parameters (propagation velocity, and amplitude and duration of the DC-shift) was evaluated in rats that received two treatments that increased cortical serotonergic activity, electrical stimulation of the raphe nuclei and subcutaneous injection of a selective serotonin reuptake inhibitor, sumatriptan...
July 24, 2017: Brain Research
https://www.readbyqxmd.com/read/28745143/high-fat-simple-carbohydrate-hfsc-diet-impairs-hypothalamic-and-corpus-striatal-serotonergic-metabolic-pathway-in-metabolic-syndrome-mets-induced-c57bl-6j-mice
#19
DSouza Serena Stephen, Asha Abraham
OBJECTIVES: To study the effect of specially formulated high-fat simple carbohydrate diet (HFSC) on the serotonin metabolic pathway in male C57BL/6J mice. METHODS: Previous studies from our laboratory have shown that specially formulated HFSC induces metabolic syndrome in C57BL/6J mice. In the present investigation, 5-hydroxytryptophan, serotonin and 5-hydroxyindoleacetic acid were analyzed in two brain regions (hypothalamus, corpus striatum), urine and plasma of HFSC-fed mice on a monthly basis up to 5 months using high-performance liquid chromatography fitted with electrochemical detector...
July 26, 2017: Nutritional Neuroscience
https://www.readbyqxmd.com/read/28744680/the-effect-of-corn-distiller-s-dried-grains-with-solubles-ddgs-fortified-with-enzyme-on-growth-performance-of-broiler
#20
Alaeldein Mahmood Abudabos, Raed Muhammad Al-Atiyat, Dragons Stanley, Rafat Aljassim, Hamad Ali Albatshan
The objective of the current study was to investigate the effect of corn distiller's dried grains with solubles (DDGS) and enzyme supplementation on growth performance and carcass yield in broiler chickens. The experiment was a 5 × 3 factorial design with 450 broiler chickens and with diets containing five levels of DDGS (0, 6, 12, 18, and 24%) and three levels of the enzymes (no supplementation, Rovabio® enzyme, and Tomoko® enzyme). Five pens with six chicks were fed an experimental diet from 0 to 35 days of age...
July 25, 2017: Environmental Science and Pollution Research International
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