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Peonidin

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https://www.readbyqxmd.com/read/29751907/the-natural-food-colorant-peonidin-from-cranberries-as-a-potential-radical-scavenger-a-dft-based-mechanistic-analysis
#1
Vijisha K Rajan, C K Hasna, K Muraleedharan
A theoretical evaluation of the antioxidant property of a natural food colorant Peonidin has been performed. The most suitable mechanism for explaining the radical scavenging capacity of Peonidin is the Hydrogen Atom Transfer and the most active site for radical formation is position 3 and is confirmed through Mulliken charge analysis, pKa value evaluation, Bond Dissociation Energy values, and Natural Bond Orbital analysis. Position 3 and 5 in Peonidin exists in blood as deprotonated as their pKa values are lower than the pH of blood...
October 1, 2018: Food Chemistry
https://www.readbyqxmd.com/read/29751487/preparation-and-antioxidant-activity-of-ethyl-linked-anthocyanin-flavanol-pigments-from-model-wine-solutions
#2
Lingxi Li, Minna Zhang, Shuting Zhang, Yan Cui, Baoshan Sun
Anthocyanin-flavanol pigments, formed during red wine fermentation and storage by condensation reactions between anthocyanins and flavanols (monomers, oligomers, and polymers), are one of the major groups of polyphenols in aged red wine. However, knowledge of their biological activities is lacking. This is probably due to the structural diversity and complexity of these molecules, which makes the large-scale separation and isolation of the individual compounds very difficult, thus restricting their further study...
May 3, 2018: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/29742931/the-intraocular-staining-potential-of-anthocyanins-and-their-retinal-biocompatibility-a-preclinical-study
#3
Lan-Hsin Chuang, An-Lun Wu, Nan-Kai Wang, Kuan-Jen Chen, Laura Liu, Yih-Shiou Hwang, Ling Yeung, Wei-Chi Wu, Chi-Chun Lai
PURPOSE: To perform preclinical studies to determine the efficacy and safety of anthocyanins as stains for the internal limiting membrane (ILM) of the eye. MATERIALS AND METHODS: Cyanidin (Cya), delphinidin (Del), luteolinidin (Lut), peonidin (Peo), and pelargonidin (Pel) were evaluated. These natural dyes were used to stain the lens capsule and ILM of pig eyes. The effects of these dyes on retinal cell viability was determined using a water-soluble tetrazolium salt assay, and oxidative stress was measured in vitro...
May 9, 2018: Cutaneous and Ocular Toxicology
https://www.readbyqxmd.com/read/29671758/anthocyanin-composition-and-content-in-rye-plants-with-different-grain-color
#4
Pavel A Zykin, Elena A Andreeva, Anna N Lykholay, Natalia V Tsvetkova, Anatoly V Voylokov
The color of grain in cereals is determined mainly by anthocyanin pigments. A large level of genetic diversity for anthocyanin content and composition in the grain of different species was observed. In rye, recessive mutations in six genes (vi1...vi6) lead to the absence of anthocyanins in all parts of the plant. Moreover, dominant genes of anthocyanin synthesis in aleurone (gene C) and pericarp (gene Vs) also affect the color of the grain. Reverse phase high-performance liquid chromatography and mass spectrometry were used to study anthocyanins in 24 rye samples...
April 19, 2018: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/29669413/rationalizing-the-color-in-heavenly-blue-anthocyanin-a-complete-kinetic-and-thermodynamic-study
#5
Johan Mendoza, Nuno Basílio, Fernando Pina, Tadao Kondo, Kumi Yoshida
All equilibrium and rate constants of heavenly blue anthocyanin (HBA 1) as well as the derivatives respectively with two (HBA 2) or none (HBA 3) acylated units were determined. The three acylated units of the sugar in position 3 of the peonidin chromophore of heavenly blue anthocyanin HBA 1 are essential to confer the peculiar stability of its purple and blue colors. The sugars generate an efficient protective environment around position 2 (and 4) of the flavylium cation, through an intramolecular sandwich type stacking that retards 40-fold the hydration reaction (kh) and increases 100-fold the dehydration reaction (k-h), when compared with the peonidin chromophore HBA 3...
April 19, 2018: Journal of Physical Chemistry. B
https://www.readbyqxmd.com/read/29606449/optimized-extraction-of-anthocyanins-from-reid-fruits-prunus-avium-lapins-cherries
#6
Melanie L Blackhall, Rachael Berry, Noel W Davies, Justin T Walls
The influence of process parameters on the extraction of anthocyanins from the edible portion of fresh, sweet cherry were investigated. The optimal extraction time and temperature were determined as 90 min and 37 °C, respectively. A solvent/solid ratio of 10 mL/g using 100% acidified solvent resulted in the greatest anthocyanin yield. No significant difference was observed between the use of methanol or ethanol as the extraction solvent. Ultra Performance Liquid Chromatography-MS analysis of the extract identified four anthocyanins, with cyanidin-3-rutinoside and peonidin-3-rutinoside accounting for over 95% of the anthocyanin content, while cyanidin-3-glucoside and pelargonidin-3-rutinoside accounted for the remaining 5%...
August 1, 2018: Food Chemistry
https://www.readbyqxmd.com/read/29579962/the-effect-of-prefermentative-addition-of-gallic-acid-and-ellagic-acid-on-the-red-wine-color-copigmentation-and-phenolic-profiles-during-wine-aging
#7
Xin-Ke Zhang, Fei He, Bo Zhang, Malcolm J Reeves, Yue Liu, Xu Zhao, Chang-Qing Duan
Though non-anthocyanin phenolics normally do not have red color, they affect the red color expression in the copigmentation of red wines. In this study, the influence of prefermentative addition of 300mg/L gallic acid and ellagic acid, as cofactors, on aging dry red wines had been systematically evaluated at the industrial scales from the perspectives of color, phenolic profiles and copigmentation effects of anthocyanins. Red wines made with these two compounds exhibited better color properties than the control, having better CIELAB chromatic parameters...
April 2018: Food Research International
https://www.readbyqxmd.com/read/29568082/antioxidant-and-prebiotic-activity-of-five-peonidin-based-anthocyanins-extracted-from-purple-sweet-potato-ipomoea-batatas-l-lam
#8
Hanju Sun, Pingping Zhang, Yongsheng Zhu, Qiuyan Lou, Shudong He
Twelve kinds of anthocyanins from the Chinese purple sweet potato cultivar (Ipomoea batatas (L.) Lam.) were extracted and identified using LC-MS/MS, which had a high content of peonidin-based anthocyanins. Five peonidin-based anthocyanin monomers (P1, P2, P3, P4 and P5) were isolated by preparative liquid chromatography with structural analyses using an Impact II Q-TOF MS/MS. Then, the functional properties of the anthocyanin monomers, such as the antioxidant activities, proliferative effects on probiotics, and their inhibition on harmful bacteria in vitro, were investigated...
March 22, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29555206/effects-of-anthocyanins-and-their-gut-metabolites-on-adenosine-diphosphate-induced-platelet-activation-and-their-aggregation-with-monocytes-and-neutrophils
#9
Irena Krga, Nevena Vidovic, Dragan Milenkovic, Aleksandra Konic-Ristic, Filip Stojanovic, Christine Morand, Marija Glibetic
Accumulating evidence suggests that anthocyanins play an important role in the cardioprotective effects associated with consumption of anthocyanin-rich foods. These benefits may partly be attributed to their effects on platelets, significant contributors to cardiovascular disease development. This study aimed to investigate the impact of physiologically relevant concentrations of anthocyanins and their metabolites on platelet activation and platelet-leukocyte aggregation. Whole blood from seven healthy volunteers was treated with anthocyanins: cyanidin-3-arabinoside, cyanidin-3-glucoside, cyanidin-3-galactoside, delphinidin-3-glucoside and peonidin-3-glucoside at 0...
March 16, 2018: Archives of Biochemistry and Biophysics
https://www.readbyqxmd.com/read/29548433/compositional-and-antioxidant-properties-of-anthocyanin-rich-products-prepared-from-purple-wheat
#10
El-Sayed M Abdel-Aal, Pierre Hucl, Iwona Rabalski
Demands for anthocyanin-rich ingredients are steadily growing due to their positive functions in human health and food coloration. Commercially available purple wheat was evaluated as a source of functional ingredients based on anthocyanin composition and antioxidant properties. Anthocyanins were concentrated in the bran fraction by about 2-fold and then the bran was further processed into anthocyanin-rich powder using ethanol extraction and column purification. Batch studies showed that anthocyanin concentration factor increased by about 81- to 135-fold in the powder depending on batch size...
July 15, 2018: Food Chemistry
https://www.readbyqxmd.com/read/29520459/isolation-purification-and-characterization-of-agucgalt1-a-galactosyltransferase-involved-in-anthocyanin-galactosylation-in-purple-celery-apium-graveolens-l
#11
Kai Feng, Zhi-Sheng Xu, Jie-Xia Liu, Jing-Wen Li, Feng Wang, Ai-Sheng Xiong
This study showed that a galactosyltransferase, AgUCGalT1, is involved in anthocyanin galactosylation in purple celery. Celery is a well-known vegetable because of its rich nutrients, low calories, and medicinal values. Its petioles and leaf blades are the main organs acting as nutrient sources. UDP-galactose: cyanidin 3-O-galactosyltransferase can transfer the galactosyl moiety from UDP-galactose to the 3-O-position of cyanidin through glycosylation. This process enhances the stability and water solubility of anthocyanins...
June 2018: Planta
https://www.readbyqxmd.com/read/29427244/anthelmintic-efficacy-of-hydro-methanolic-extracts-of-larrea-tridentata-against-larvae-of-haemonchus-contortus
#12
José E García, Leónides Gómez, Pedro Mendoza-de-Gives, José L Rivera-Corona, Jair Millán-Orozco, Juan A Ascacio, Miguel A Medina, Miguel Mellado
An in vitro study was conducted to determine the anthelminthic activity of hydro-methanolic extracts of Larrea tridentata on sheathed and exsheathed larvae of Haemonchus contortus. Larvae of the parasite were incubated at 20-25 °C in hydro-methanolic extracts at concentrations of 12.5, 25, 50, 100, and 200 mg/mL for 24, 48, or 72 h. Ivermectin and water were the positive and negative controls, respectively. Total phenolic compounds of leaves of L. tridentata were 97.88 ± 10.45 mg/g of dry matter. Other compounds detected in this shrub by HPLC-mass spectrometry were sesamin, galocatechin, peonidin 3-O rutinoside, methyl galangin, epigallocatechin 7-O-glucuronide, and epigalocatechin...
February 9, 2018: Tropical Animal Health and Production
https://www.readbyqxmd.com/read/29370193/inhibition-of-%C3%AE-glucosidase-%C3%AE-amylase-and-aldose-reductase-by-potato-polyphenolic-compounds
#13
Diganta Kalita, David G Holm, Daniel V LaBarbera, J Mark Petrash, Sastry S Jayanty
Diabetes mellitus is a chronic disease that is becoming a serious global health problem. Diabetes has been considered to be one of the major risks of cataract and retinopathy. Synthetic and natural product inhibitors of carbohydrate degrading enzymes are able to reduce type 2 diabetes and its complications. For a long time, potatoes have been portrayed as unhealthy for diabetic patients by some nutritionist due to their high starch content. However, purple and red potato cultivars have received considerable attention from consumers because they have high levels of polyphenolic compounds that have potent antioxidant activities...
2018: PloS One
https://www.readbyqxmd.com/read/29337409/engineering-of-purple-embryo-maize-with-a-multigene-expression-system-derived-from-a-bidirectional-promoter-and-self-cleaving-2a-peptides
#14
LETTER
Xiaoqing Liu, Wenzhu Yang, Bona Mu, Suzhen Li, Ye Li, Xiaojin Zhou, Chunyi Zhang, Yunliu Fan, Rumei Chen
No abstract text is available yet for this article.
January 16, 2018: Plant Biotechnology Journal
https://www.readbyqxmd.com/read/29220052/hypoglycemic-and-hypolipidemic-effects-of-anthocyanins-extract-from-black-soybean-seed-coat-in-high-fat-diet-and-streptozotocin-induced-diabetic-mice
#15
Zhongqin Chen, Cong Wang, Yuxiang Pan, Xudong Gao, Haixia Chen
Black soybean seed coat extract (BSSCE) is a rich source of anthocyanins with multiple health effects. This study was aimed at investigating the composition and hypoglycemic and hypolipidemic effects of BSSCE in vitro and in a high-fat diet and streptozotocin (STZ)-induced diabetic mice. The anthocyanins of BSSCE were identified as cyanidin-3-O-glucoside, delphinidin-3-O-glucoside, and peonidin-3-O-glucoside by HPLC-MS. Results demonstrated that BSSCE exhibited strong inhibitory activities for α-amylase, potent inhibition activity against lipid accumulation in HepG2 cells and protection effect on H2 O2 -induced oxidative stress-damaged HepG2 cells...
January 24, 2018: Food & Function
https://www.readbyqxmd.com/read/29210634/preventive-and-therapeutic-potentials-of-anthocyanins-in-diabetes-and-associated-complications
#16
Swathi Putta, Nagendra Sastry Yarla, Eswar K Kumar, Dhananjaya Bhadrapura Lakkappa, Mohammad A Kamal, Luciana Scotti, Marcus T Scotti, Ghulam Md Ashraf, George E Barreto, B Sasi Bhusana Rao, D Sarala Kumari, Gorla V Reddy, Vadim V Tarasov, Sarat Babu Imandi, Gjumrakch Aliev
Diet is an essential factor affecting the development of and risk for diabetes mellitus. In search of preventative and therapeutic strategies, it is to be considering the potential role of certain foods and their bioactive compounds to prevent the pathogenesis associated with metabolic diseases. Human consumption of anthocyanins is among the highest of all flavonoids. Epidemiological studies have suggested that the consumption of anthocyanins lowers the risk of diabetes and diabetic complications. Anthocyanins are important natural bioactive pigments responsible for red to blue colour of fruits, leaves, seeds, stems and flowers, which are present in a variety of plant species particularly in berries and cherries...
December 5, 2017: Current Medicinal Chemistry
https://www.readbyqxmd.com/read/29196236/berries-containing-anthocyanins-with-enhanced-methylation-profiles-are-more-effective-at-ameliorating-high-fat-diet-induced-metabolic-damage
#17
Emily Skates, John Overall, Katelyn DeZego, Mickey Wilson, Debora Esposito, Mary Ann Lila, Slavko Komarnytsky
Driven by the need for alternative whole food options to manage metabolic syndrome, multiple dietary interventions are suggested to achieve a better control of metabolic risk factors and molecular networks that regulate cellular energy metabolism. It is generally accepted that anthocyanin-rich diets are beneficial for maintaining healthy body weight, improving glucose and lipid metabolism, and determining inflammatory status of key metabolic tissues. However, anthocyanins are a structurally diverse group of phenolic compounds and their individual contributions to improving metabolic health are not clear...
January 2018: Food and Chemical Toxicology
https://www.readbyqxmd.com/read/29174054/effect-of-polyphenols-from-coffee-and-grape-on-gene-expression-in-myoblasts
#18
Alexandros Priftis, Nikolaos Goutzourelas, Maria Halabalaki, Georgia Ntasi, Dimitrios Stagos, Grigorios D Amoutzias, Leandros A Skaltsounis, Dimitrios Kouretas
Coffee and grape contain various bioactive compounds like polyphenols that may exert beneficial effects, especially antioxidant activity, on human health upon consumption. However, the molecular mechanisms through which these effects are achieved are not fully elucidated. Thus, in the present study in order to investigate these mechanisms, a whole genome expression DNA microarray analysis was carried out in myoblasts treated with polyphenols of coffee and grape pomace at concentrations that improved the redox status...
November 23, 2017: Mechanisms of Ageing and Development
https://www.readbyqxmd.com/read/29072505/profiling-of-anthocyanidins-against-transcriptional-activities-of-steroid-and-nuclear-receptors
#19
Barbora Pastorková, Petr Illés, Zdeněk Dvořák
The aim of current study was to evaluate the effect of the most common anthocyanidins (cyanidin, delphinidin, malvidin, pelargonidin, and peonidin) on the transcriptional activity of steroid and nuclear receptors. The activities of steroid receptors - progesterone receptor (PR), estrogen receptor (ER), androgen receptor (AR), glucocorticoid receptor (GR), and nuclear receptors - vitamin D receptor (VDR), retinoid X receptor (RXR), retinoic acid receptor (RAR), pregnane X receptor (PXR), and thyroid receptor (TR) were assessed using either stable transfected luciferase gene reporter cell lines or transiently transfected cell lines...
October 26, 2017: Drug and Chemical Toxicology
https://www.readbyqxmd.com/read/28974032/dietary-anthocyanins-against-obesity-and-inflammation
#20
REVIEW
Yoon-Mi Lee, Young Yoon, Haelim Yoon, Hyun-Min Park, Sooji Song, Kyung-Jin Yeum
Chronic low-grade inflammation plays a pivotal role in the pathogenesis of obesity, due to its associated chronic diseases such as type II diabetes, cardiovascular diseases, pulmonary diseases and cancer. Thus, targeting inflammation is an attractive strategy to counter the burden of obesity-induced health problems. Recently, food-derived bioactive compounds have been spotlighted as a regulator against various chronic diseases due to their low toxicity, as opposed to drugs that induce severe side effects. Here we describe the beneficial effects of dietary anthocyanins on obesity-induced metabolic disorders and inflammation...
October 1, 2017: Nutrients
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