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https://www.readbyqxmd.com/read/29785573/effect-of-dietary-soy-oil-glucose-and-glutamine-on-growth-performance-amino-acid-profile-blood-profile-immunity-and-antioxidant-capacity-in-weaned-piglets
#1
Dinghong Lv, Xia Xiong, Huansheng Yang, Meiwei Wang, Yijie He, Yanhong Liu, Yulong Yin
Weaning stress results in gastrointestinal dysfunction and depressed performance in pigs. This study aimed to investigate the effect of soy oil, glucose, and glutamine on the growth and health of weaned piglets. Compared with those in the glutamine group, piglets in the glucose and soy oil groups had greater average daily gain, average daily feed intake, and gain: feed ratio from day 0 to 14, and gain: feed ratio for the overall period. There were no differences with regard to serum amino acids among the three groups on day 14, except glycine and threonine...
May 18, 2018: Science China. Life Sciences
https://www.readbyqxmd.com/read/29785263/methodologies-on-estimating-the-energy-requirements-for-maintenance-and-determining-the-net-energy-contents-of-feed-ingredients-in-swine-a-review-of-recent-work
#2
REVIEW
Zhongchao Li, Hu Liu, Yakui Li, Zhiqian Lv, Ling Liu, Changhua Lai, Junjun Wang, Fenglai Wang, Defa Li, Shuai Zhang
In the past two decades, a considerable amount of research has focused on the determination of the digestible (DE) and metabolizable energy (ME) contents of feed ingredients fed to swine. Compared with the DE and ME systems, the net energy (NE) system is assumed to be the most accurate estimate of the energy actually available to the animal. However, published data pertaining to the measured NE content of ingredients fed to growing pigs are limited. Therefore, the Feed Data Group at the Ministry of Agricultural Feed Industry Centre (MAFIC) located at China Agricultural University has evaluated the NE content of many ingredients using indirect calorimetry...
2018: Journal of Animal Science and Biotechnology
https://www.readbyqxmd.com/read/29784082/novel-transgenic-pigs-with-enhanced-growth-and-reduced-environmental-impact
#3
Xianwei Zhang, Zicong Li, Huaqiang Yang, Dewu Liu, Gengyuan Cai, Guoling Li, Jianxin Mo, Dehua Wang, Cuili Zhong, Haoqiang Wang, Yue Sun, Junsong Shi, Enqin Zheng, Fanming Meng, Mao Zhang, Xiaoyan He, Rong Zhou, Jian Zhang, Miaorong Huang, Ran Zhang, Ning Li, Mingzhe Fan, Jinzeng Yang, Zhenfang Wu
In pig production, inefficient feed digestion causes excessive nutrients such as phosphorus and nitrogen to be released to the environment. To address the issue of environmental emissions, we established transgenic pigs harboring a single-copy quad-cistronic transgene and simultaneously expressing three microbial enzymes, β-glucanase, xylanase, and phytase in the salivary glands. All the transgenic enzymes were successfully expressed, and the digestion of non-starch polysaccharides (NSPs) and phytate in the feedstuff was enhanced...
May 22, 2018: ELife
https://www.readbyqxmd.com/read/29783637/a-phosphatidylserine-source-of-docosahexanoic-acid-improves-neurodevelopment-and-survival-of-preterm-pigs
#4
Randal K Buddington, Victor V Chizhikov, Igor Y Iskusnykh, Helen J Sable, Jeffrey J Sable, Zade R Holloway, Tamar Blumenfeld Katzir, Marie van der Merwe, Taisiya Yakimkova, Karyl K Buddington, Yael Lifshitz, Shoshi Tessler, Ariel Gilbert
The amount, composition, and sources of nutrition support provided to preterm infants is critical for normal growth and development, and particularly for structural and functional neurodevelopment. Although omega-3 long chain polyunsaturated fatty acids (LC-PUFA), and particularly docosahexanoic acid (DHA), are considered of particular importance, results from clinical trials with preterm infants have been inconclusive because of ethical limitations and confounding variables. A translational large animal model is needed to understand the structural and functional responses to DHA...
May 18, 2018: Nutrients
https://www.readbyqxmd.com/read/29783624/growth-responses-of-preterm-pigs-fed-formulas-with-different-protein-levels-and-supplemented-with-leucine-or-%C3%AE-hydroxyl-%C3%AE-methylbutyrate
#5
Randal K Buddington, Scott C Howard, Harold W Lee, Karyl K Buddington
Growth after preterm birth is an important determinant of long-term outcomes. Yet, many preterm infants suffer ex utero growth retardation. We evaluated effects of leucine and the metabolite, β-hydroxy β-methylbutyrate (HMB) on growth of preterm pigs, a previously-validated translational model for preterm infants. After 48 h of parenteral nutrition preterm pigs were fed for 6 to 7 days isocaloric formulas with different levels of protein (50 or 100 g/L) with leucine (10 g/L, 76 mM) or HMB (at 1.1 g/L, 4 mM) added to stimulate protein synthesis or with alanine (6...
May 18, 2018: Nutrients
https://www.readbyqxmd.com/read/29778185/serine-105-and-120-are-important-phosphorylation-sites-for-porcine-reproductive-and-respiratory-syndrome-virus-n-protein-function
#6
Yao Chen, Xiulin Xing, Qi Li, Songlin Feng, Xiaoliang Han, Shuyi He, Guihong Zhang
The nucleocapsid (N) protein is the most abundant protein of porcine reproductive and respiratory syndrome virus (PRRSV). It has been shown to be multiphosphorylated. However, the phosphorylation sites are still unknown. In this study, we used liquid chromatography tandem mass spectrometry (LC-MS/MS) to analyze the phosphorylation sites of N protein expressed in Sf9 cells. The results showed that N protein contains two phosphorylation sites. Since N protein can regulate IL-10, which may facilitate PRRSV replication, we constructed four plasmids (pCA-XH-GD, pCA-A105, pCA-A120 and pCA-A105-120) and transfected them into Pig alveolar macrophages (PAMs,3D4/2)...
June 2018: Veterinary Microbiology
https://www.readbyqxmd.com/read/29777914/the-full-length-microrna-cluster-in-the-intron-of-large-latency-transcript-is-associated-with-the-virulence-of-pseudorabies-virus
#7
Xin Wang, Mei-Mei Zhang, Kai Yan, Qi Tang, Yi-Quan Wu, Wen-Bo He, Huan-Chun Chen, Zheng-Fei Liu
Pseudorabies virus (PRV), the etiological pathogen of Aujeszky's disease, belongs to the Alphaherpesvirus subfamily. Large latency transcript (LLT), the most abundant PRV transcript, harbors a ~ 4.6 kb microRNA (miRNA) cluster-encoding intron. To investigate the function of the LLT miRNA cluster during the life cycle of PRV, we generated a miRNA cluster mutation virus (PRV-∆miR cluster) and revertant virus. Analysis of the growth kinetics of PRV-ΔmiR cluster-infected cells revealed significantly smaller plaques and lower titers than the wild-type and revertant viruses...
May 16, 2018: Virology
https://www.readbyqxmd.com/read/29775545/effect-of-bamboo-vinegar-powder-as-an-antibiotic-alternative-on-the-digesta-bacteria-communities-of-finishing-pigs
#8
Huan Qu, Yanjie Huang, Yinghao Shi, Ying Liu, Shenglong Wu, Wenbin Bao
This study investigated the use for bamboo vinegar powder as an antibiotic alternative in the diet of growing-finishing pigs by examining their digestive bacterial communities. Forty-five Duroc × Landrace × Yorkshire growing-finishing pigs were randomly allocated to five diet groups: 0%,0.5%, 1.0%, or 1.5% bamboo vinegar levels and antibiotics. After 37 days, the digesta in duodenum of four pigs from each treatment were analyzed for their bacterial community compositions using 16S rRNA gene sequencing. Addition of 1...
May 18, 2018: Canadian Journal of Microbiology
https://www.readbyqxmd.com/read/29773876/early-salmonella-typhimurium-infection-in-pigs-disrupts-microbiome-composition-and-functionality-principally-at-the-ileum-mucosa
#9
Héctor Argüello, Jordi Estellé, Sara Zaldívar-López, Ángeles Jiménez-Marín, Ana Carvajal, Mª Asunción López-Bascón, Fiona Crispie, Orla O'Sullivan, Paul D Cotter, Feliciano Priego-Capote, Luis Morera, Juan J Garrido
Salmonella is a major foodborne pathogen which successfully infects animal species for human consumption such as swine. The pathogen has a battery of virulence factors which it uses to colonise and persist within the host. The host microbiota may play a role in resistance to, and may also be indirectly responsible from some of the consequences of, Salmonella infection. To investigate this, we used 16S rRNA metagenomic sequencing to determine the changes in the gut microbiota of pigs in response to infection by Salmonella Typhimurium at three locations: ileum mucosa, ileum content and faeces...
May 17, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29772815/longitudinal-effects-of-iron-deficiency-anemia-and-subsequent-repletion-on-blood-parameters-and-the-rate-and-composition-of-growth-in-pigs
#10
Laura C Knight, Ryan N Dilger
Iron deficiency is reported as the most common nutrient deficiency worldwide. Due to rapid growth, infants are at particular risk for developing iron deficiency, which can easily progress to iron deficiency anemia (IDA), if not treated. The aim of this study was to determine the lasting effects of an early-life iron deficiency after a period of dietary iron repletion. Forty-two intact male pigs were fed, ad libitum , either control (CONT, 21.3 mg Fe/L) or iron-deficient (ID 2.72 mg Fe/L) milk replacer from postnatal day (PND) 2 to 32 (phase 1)...
May 17, 2018: Nutrients
https://www.readbyqxmd.com/read/29771404/mmp-2-participates-in-the-sclera-of-guinea-pig-with-form-deprivation-myopia-via-igf-1-stat3-pathway
#11
Y-X Liu, Y Sun
OBJECTIVE: To investigate the expression changes of MMP-2 (matrix metalloproteinases-2) mediated by IGF-1 (insulin-like growth factors-1) STAT3 (signal transducer and activator of transcription 3) pathway in the sclera of the form-deprivation myopia guinea pigs. MATERIALS AND METHODS: Twenty-four three-week-old guinea pigs were randomly divided into 4 groups: group A (Control), B, C and D. Guinea pigs in group A were sacrificed after 21 days without any special treatment...
May 2018: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/29770950/heme-and-non-heme-iron-on-growth-performances-blood-parameters-tissue-mineral-concentration-and-intestinal-morphology-of-weanling-pigs
#12
Zhao Zhuo, Xiaonan Yu, Sisi Li, Shenglin Fang, Jie Feng
This experiment was conducted to evaluate the effects of heme and non-heme iron sources on growth performances, blood parameters, tissue mineral concentration, and intestinal morphology in weanling pigs. At 25 days of age, 32 newly weaned piglets (Duroc × Landrace × Yorkshire; 8.66 ± 0.59 kg) were allocated to one of the following dietary treatments: control group (basal diet with no extra iron addition), FeSO4 group (basal diet + 100 mg Fe/kg as FeSO4 ), Fe-Gly group (basal diet + 100 mg Fe/kg as Fe-Gly), and Heme group (basal diet + 100 mg Fe/kg as Heme)...
May 16, 2018: Biological Trace Element Research
https://www.readbyqxmd.com/read/29768541/vascular-endothelial-growth-factor-association-with-angiopoietin-1-promotes-improvement-in-ventricular-function-after-ischemic-cardiomyopathy-induced-in-mini-pigs
#13
André Lacerda de Abreu Oliveira, Jussara Peters Scheffer, Melissa Markoski, Andreia Koche, Alexsandra Balbinot, Fernanda Antunes, Renato Kalil
PURPOSE: To investigate the safety and clinical, hemodynamic and tissue improvement ability in mini pigs undergoing cell and gene therapy for the treatment of acute myocardial infarction. METHODS: Thirty-two mini pigs Br1 lineage, 12 months old, undergoing induction of acute myocardial infarction by occlusion of the diagonal branch of the paraconal coronary. They were divided into 4 groups: one control group and 3 treatment groups (cell therapy and gene cell therapy)...
April 2018: Acta Cirúrgica Brasileira
https://www.readbyqxmd.com/read/29767244/propranolol-induces-hemangioma-endothelial-cell-apoptosis-via-a-p53%C3%A2-bax-mediated-pathway
#14
Tian-Hua Yao, Parekejiang Pataer, Krishna Prasad Regmi, Xi-Wen Gu, Quan-Yan Li, Jing-Ting Du, Su-Meng Ge, Jun-Bo Tu
The use of propranolol for the treatment of infantile hemangioma (IH) has been widely investigated in recent years. However, the underlying therapeutic mechanism of propranolol for the treatment of IH remains poorly understood. The aim of the present study was to investigate the expression of proteins regulated by cellular tumor antigen p53 (p53) in associated apoptosis pathways in IH endothelial cells (HemECs) treated with propranolol. Furthermore, the present study aimed to investigate the exact apoptotic pathway underlying the therapeutic effect of propranolol against IH...
May 14, 2018: Molecular Medicine Reports
https://www.readbyqxmd.com/read/29767172/post-weaning-and-whole-of-life-performance-of-pigs-is-determined-by-live-weight-at-weaning-and-the-complexity-of-the-diet-fed-after-weaning
#15
Cherie L Collins, John R Pluske, Rebecca S Morrison, Trevor N McDonald, Robert J Smits, David J Henman, Ingunn Stensland, Frank R Dunshea
The production performance and financial outcomes associated with weaner diet complexity for pigs of different weight classes at weaning were examined in this experiment. A total of 720 weaner pigs (360 entire males and 360 females) were selected at weaning (27 ± 3 d) and allocated to pens of 10 based on individual weaning weight (light weaning weight: pigs below 6.5 kg; medium weaning weight: 6.5 to 8 kg; heavy weaning weight: above 8.5 kg). Pens were then allocated in a 3 × 2 × 2 factorial arrangement of treatments with the respective factors being weaning weight (heavy, medium and light; H, M and L, respectively), weaner diet complexity (high complexity/cost, HC; low complexity/cost, LC), and gender (male and female)...
December 2017: Animal nutrition
https://www.readbyqxmd.com/read/29767154/husbandry-practices-and-gut-health-outcomes-in-weaned-piglets-a-review
#16
REVIEW
Balachandar Jayaraman, Charles M Nyachoti
The immediate post-weaning period is one of the most stressful phases in a pig's life, and during this period, piglets are usually exposed to environmental, social and psychological stressors which have direct or indirect effects on gut health and overall growth performance. In this review, the impact of husbandry practices on gut health outcomes and performance of piglets is discussed. Husbandry practices in the swine barn generally include nutrition and management practices, maintenance of hygienic standards and disease prevention protocols, and animal welfare considerations...
September 2017: Animal nutrition
https://www.readbyqxmd.com/read/29767144/growth-performance-of-nursery-and-grower-finisher-pigs-fed-diets-supplemented-with-benzoic-acid
#17
Hengxiao Zhai, Wen Ren, Shikui Wang, Jinlong Wu, Patrick Guggenbuhl, Anna-Maria Kluenter
Two experiments were conducted to investigate the efficacy of benzoic acid on the growth performance of nursery and grower-finisher pigs. A randomized complete block design was used in both experiments with the initial body weight as the blocking factor. There were 3 treatments corresponding to 3 dietary levels of benzoic acid: 0, 0.3%, and 0.5%. In experiment 1, a total of 144 PIC L1050 barrows (initial body weight 7.1 ± 0.6 kg) were used with each treatment replicated 8 times. In experiment 2, a total of 288 PIC L1050 barrows (initial body weight 36...
September 2017: Animal nutrition
https://www.readbyqxmd.com/read/29767135/impacts-of-energy-feeds-and-supplemental-protease-on-growth-performance-nutrient-digestibility-and-gut-health-of-pigs-from-18-to-45-kg-body-weight
#18
Hongyu Chen, Shihai Zhang, Inkyung Park, Sung Woo Kim
A total of 144 pigs with 18.4 ± 2.3 kg initial body weight (BW) at 6 wk of age were used in a 40-d trial to evaluate effects of protease (300,000 U/kg feed, BioResource International Inc., Durham, NC, USA) on growth performance, apparent ileal digestibility (AID) of nutrients, and gut health of pigs fed diets with sorghum. Pigs were randomly allotted to 4 treatments (12 pens per treatment, 3 pigs per pen) in a 2 × 2 factorial arrangement (corn or sorghum basal diets, and 0 or 0.05% protease as 2 factors) with sex and initial BW as blocks...
December 2017: Animal nutrition
https://www.readbyqxmd.com/read/29767133/intestinal-challenge-with-enterotoxigenic-escherichia-coli-in-pigs-and-nutritional-intervention-to-prevent-postweaning-diarrhea
#19
REVIEW
Yawang Sun, Sung Woo Kim
Gut health of nursery pigs immediately after weaning is tightly associated with their growth performance and economic values. Postweaning diarrhea (PWD) is one of the major concerns related to gut health of nursery pigs which often is caused by infections of enterotoxigenic Escherichia coli (ETEC), mainly including F4 (K88)+ and F18+ E. coli. The main virulence factors of ETEC are adhesins (fimbriae or pili) and enterotoxins. The common types of fimbriae on ETEC from PWD pigs are F18+ and F4+ . Typically, PWD in pigs is associated with both F18+ and F4+ ETEC infections whereas pre-weaning diarrhea in pigs is associated with F4+ ETEC infection...
December 2017: Animal nutrition
https://www.readbyqxmd.com/read/29767131/effect-of-chicken-egg-anti-f4-antibodies-on-performance-and-diarrhea-incidences-in-enterotoxigenic-escherichia-coli-k88-challenged-piglets
#20
Kolawole Aluko, Deepak E Velayudhan, Ehsan Khafipour, Lin Fang, Martin Nyachoti
The aim was to evaluate the effects of dietary supplementation of spay-dried whole egg containing anti-F4 antibodies (SDWE) against recombinantly produced F4 antigens in enterotoxigenic Escherichia coli K88+ (ETEC)-challenged piglets. Twenty-seven 21-d-old and individually housed piglets were randomly allotted to 3 treatments consisting of a wheat-soybean meal basal diet containing either 0 (control egg powder; CEP), 0.1% (SDWE1) or 0.4% (SDWE2) SDWE. After a 7-d adaptation period, blood samples were collected from all pigs, and pigs were weighed and orally challenged with an ETEC inoculum...
December 2017: Animal nutrition
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