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https://www.readbyqxmd.com/read/28935871/evaluation-of-biochars-from-different-stock-materials-as-carriers-of-bacterial-strain-for-remediation-of-heavy-metal-contaminated-soil
#1
Ting Wang, Hongwen Sun, Xinhao Ren, Bing Li, Hongjun Mao
Two kinds of biochars, one derived from corn straw and one from pig manure, were studied as carriers of a mutant genotype from Bacillus subtilis (B38) for heavy metal contaminated soil remediation. After amendment with biochar, the heavy metal bioavailability decreased. Moreover, the heavy metal immobilization ability of the biochar was enhanced by combining it with B38. The simultaneous application of B38 and pig manure-derived biochar exhibited a superior effect on the promotion of plant growth and the immobilization of heavy metals in soil...
September 21, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28931675/comparative-transcriptomics-highlights-the-role-of-the-ap1-transcription-factor-in-the-host-response-to-ebolavirus
#2
James W Wynne, Shawn Todd, Victoria Boyd, Mary Tachedjian, Reuben Klein, Brian Shiell, Megan Dearnley, Alexander J McAuley, Amanda P Woon, Anthony W Purcell, Glenn A Marsh, Michelle L Baker
Ebolavirus and Marburgvirus comprise two genera of negative-sense single-stranded RNA viruses that cause severe hemorrhagic fevers in humans. Despite considerable research efforts, the molecular events following Ebola virus (EBOV) infection are poorly understood. With the view of identifying host factors that underpin EBOV pathogenesis, we compared the transcriptomes of EBOV-infected human, pig and bat kidney cells using an RNAseq approach. Despite a significant difference in viral transcription/replication between the cell lines, all cells responded to EBOV infection through a robust induction of extracellular growth factors...
September 20, 2017: Journal of Virology
https://www.readbyqxmd.com/read/28930250/enrichment-of-animal-diets-with-essential-oils-a-great-perspective-on-improving-animal-performance-and-quality-characteristics-of-the-derived-products
#3
REVIEW
Panagiotis E Simitzis
Food industry operates in a competitive market and is continually facing challenges to retain or even increase its market share. Consistent high-quality animal products are required to maintain consumer confidence and consumption. Enrichment of foods with bioactive compounds such as the essential oils appears to improve quality characteristics of the derived products and protects consumers against oxidation and bacterial spoilage effects. Synthetic additives are nowadays questioned due to their suspected carcinogenic potential, and therefore extensive research has been undertaken to identify safe and efficient alternatives...
June 2, 2017: Medicines (Basel, Switzerland)
https://www.readbyqxmd.com/read/28929911/understanding-the-effects-of-intermittent-shedding-on-the-transmission-of-infectious-diseases-example-of-salmonellosis-in-pigs
#4
Glenn E Lahodny, Raju Gautam, Renata Ivanek
A number of environmentally transmitted infectious diseases are characterized by intermittent infectiousness of infected hosts. However, it is unclear whether intermittent infectiousness must be explicitly accounted for in mathematical models for these diseases or if a simplified modelling approach is acceptable. To address this question we study the transmission of salmonellosis between penned pigs in a grower-finisher facility. The model considers indirect transmission, growth of free-living Salmonella within the environment, and environmental decontamination...
December 2017: Journal of Biological Dynamics
https://www.readbyqxmd.com/read/28929384/roles-of-dietary-glycine-proline-and-hydroxyproline-in-collagen-synthesis-and-animal-growth
#5
REVIEW
Peng Li, Guoyao Wu
Glycine, proline, and hydroxyproline (Hyp) contribute to 57% of total amino acids (AAs) in collagen, which accounts for one-third of proteins in animals. As the most abundant protein in the body, collagen is essential to maintain the normal structure and strength of connective tissue, such as bones, skin, cartilage, and blood vessels. Mammals, birds, and fish can synthesize: (1) glycine from threonine, serine, choline, and Hyp; (2) proline from arginine; and (3) Hyp from proline residues in collagen, in a cell- and tissue-specific manner...
September 20, 2017: Amino Acids
https://www.readbyqxmd.com/read/28923649/hypothermic-machine-perfusion-s-protection-on-porcine-kidney-graft-uncovers-greater-akt-erk-phosphorylation
#6
N He, J-H Li, J-J Jia, K-D Xu, Y-F Zhou, L Jiang, H-H Lu, S-Y Yin, H-Y Xie, L Zhou, S-S Zheng
BACKGROUND: To investigate the potential mechanisms of hypothermic machine perfusion (HMP)'s beneficial effects on kidney graft over static cold storage (SCS) in vitro. METHODS: Ten kidneys of 5 Bama miniature male pigs were paired into 2 groups: SCS group and HMP group. Preservation solutions were taken at 0, 1, 3, and 6 hours for the measurement of K(+), Na(+), Cl(-), blood urea nitrogen (BUN), creatinine (Cr), and lactate dehydrogenase (LDH) using the standard laboratory methods...
October 2017: Transplantation Proceedings
https://www.readbyqxmd.com/read/28920404/effects-of-zearalenone-on-the-localization-and-expression-of-the-growth-hormone-receptor-gene-in-the-uteri-of-post-weaning-piglets
#7
Min Zhou, LiJie Yang, Weiren Yang, Libo Huang, Xuemei Zhou, Shuzhen Jiang, Zaibin Yang
Objective: In this study, we investigated the adverse effects of dietary zearalenone (ZEA) (0.5 to 1.5 mg•kg-1 diet) on the localization and expression of the growth hormone receptor (GHR) in the uteri of post-weaning gilts and explored another mechanism of the reproductive toxicity of ZEA on piglets. Methods: A total of forty healthy piglets (Duroc × Landrace × Large White) aged 28 d were selected for study. Piglets were transferred to single cages after 10 days' adaptation on an obstetric table...
September 18, 2017: Asian-Australasian Journal of Animal Sciences
https://www.readbyqxmd.com/read/28919976/impacts-of-prenatal-nutrition-on-animal-production-and-performance-a-focus-on-growth-and-metabolic-and-endocrine-function-in-sheep
#8
REVIEW
Prabhat Khanal, Mette Olaf Nielsen
The concept of foetal programming (FP) originated from human epidemiological studies, where foetal life nutrition was linked to health and disease status later in life. Since the proposal of this phenomenon, it has been evaluated in various animal models to gain further insights into the mechanisms underlying the foetal origins of health and disease in humans. In FP research, the sheep has been quite extensively used as a model for humans. In this paper we will review findings mainly from our Copenhagen sheep model, on the implications of late gestation malnutrition for growth, development, and metabolic and endocrine functions later in life, and discuss how these implications may depend on the diet fed to the animal in early postnatal life...
2017: Journal of Animal Science and Biotechnology
https://www.readbyqxmd.com/read/28915727/the-protein-and-energy-metabolic-response-of-skeletal-muscle-to-the-low-protein-diets-in-growing-pigs
#9
Yinghui Li, Fengna Li, Yehui Duan, Qiuping Guo, Wenlong Wang, Chaoyue Wen, Xingguo Huang, Yulong Yin
This study was conducted to determine the effect of the low-protein diets on protein and energy metabolism in skeletal muscle, and to elucidate the underlying mechanism. A total of 18 growing pigs (average initial body weight = 36.47 kg) were individually penned and assigned to three treatments, each treatment was fed one of three diets containing either 18%, 15%, or 12% CP. The results showed that reducing dietary CP contents decreased (P < 0.05) the weight of half Longissimus dorsi (LD) muscle and serum concentration of insulin-like growth factor 1 (IGF-1)...
September 15, 2017: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/28915498/tantalum-coated-pedicle-screws-enhance-implant-integration
#10
Liang-Yu Shi, An Wang, Fa-Zhi Zang, Jian-Xi Wang, Xian-Wei Pan, Hua-Jiang Chen
Because titanium alloy (Ti) has the natural advantage of a low elastic modulus, it has become the most commonly used material for the manufacturing of pedicle screws. However, its poor shear strength and osteogenic ability are undesirable properties. The superior osteoinductivity demonstrated by tantalum (Ta) in oral and maxillofacial surgery and joint surgery leads us to assume that the tantalum-coated pedicle screws may have better osteogenic properties and bone anchoring strength. To verify this hypothesis, MC3T3-E1 cells and human mesenchymal stem cells (hBMSCs) were seeded on the surface of Ta and Ti disks to compare the effects of two different metals on cell adhesion, proliferation, and differentiation...
September 7, 2017: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/28913296/effect-of-relaxin-expressing-adenovirus-on-scar-remodeling-a-preliminary-study
#11
Bok Ki Jung, Won Jai Lee, Eunhye Kang, Hyo Min Ahn, Yong Oock Kim, Dong Kyun Rah, Chae-Ok Yun, In Sik Yun
BACKGROUND: Relaxin is a transforming growth factor β1 antagonist. To determine the effects of relaxin on scar reduction, we investigated the scar remodeling process by injecting relaxin-expressing adenoviruses using a pig scar model. METHODS: Scars with full thickness were generated on the backs of Yorkshire pigs. Scars were divided into two groups (relaxin [RLX] and Control). Adenoviruses were injected into the RLX (expressing relaxin) and Control (not expressing relaxin) groups...
March 2017: Arch Craniofac Surg
https://www.readbyqxmd.com/read/28894978/hydrogen-rich-saline-ameliorates-allergic-rhinitis-by-reversing-the-imbalance-of-th1-th2-and-up-regulation-of-cd4-cd25-foxp3-regulatory-t-cells-interleukin-10-and-membrane-bound-transforming-growth-factor-%C3%AE-in-guinea-pigs
#12
Feifei Xu, Shaoqing Yu, Mali Qin, Yong Mao, Ling Jin, Na Che, Shuangxi Liu, Rongming Ge
It is well known that CD4+CD25+Foxp3+Treg cells play an important role in the development of allergic rhinitis (AR); the defect of cell numbers and functions contribute to AR. Hydrogen has been proven effective in alleviating symptoms of AR. We herein aim to verify the protective effects of hydrogen on CD4+CD25+Foxp3+Treg cells in guinea pigs with AR and to explore the effect of hydrogen-rich saline (HRS) on CD4+CD25+Foxp3+Treg cells in animals with AR and investigate the underlying anti-inflammatory mechanism...
September 11, 2017: Inflammation
https://www.readbyqxmd.com/read/28894511/the-evaluation-of-antioxidant-and-anti-inflammatory-effects-of-eucommia-ulmoides-flavones-using-diquat-challenged-piglet-models
#13
Daixiu Yuan, Tarique Hussain, Bie Tan, Yanhong Liu, Peng Ji, Yulong Yin
This study was designed to evaluate the antioxidant and anti-inflammatory effects of Eucommia ulmoides flavones (EUF) using diquat-challenged piglet models. A total of 96 weaned piglets were randomly allotted to 1 of 3 treatments with 8 replication pens per treatment and 4 piglets per pen. The treatments were basal diet, basal diet + diquat, and 100 mg/kg EUF diet + diquat. On day 7 after the initiation of treatment, the piglets were injected intraperitoneally with diquat at 8 mg/kg BW or the same amount of sterilized saline...
2017: Oxidative Medicine and Cellular Longevity
https://www.readbyqxmd.com/read/28893896/sildenafil-during-pregnancy-a-preclinical-meta-analysis-on-fetal-growth-and-maternal-blood-pressure
#14
Nina D Paauw, Fieke Terstappen, Wessel Ganzevoort, Jaap A Joles, Hendrik Gremmels, A Titia Lely
Sildenafil is a new approach to treat fetal growth restriction (FGR) and preeclampsia. We performed a systematic meta-analysis to evaluate effects of sildenafil. Our search identified 22 animal studies (mouse, rat, rabbit, sheep, and guinea pigs) and 2 human randomized controlled trials. Data were pooled using ratio of means and mean differences with 95% confidence intervals for fetal growth and maternal blood pressure, respectively. Meta-regression analyses were performed for study-related factors that might affect efficacy of sildenafil, including the model used (healthy pregnancy versus FGR/preeclampsia) and route of administration...
September 11, 2017: Hypertension
https://www.readbyqxmd.com/read/28890999/a-genome-wide-association-study-identifies-genomic-loci-associated-with-backfat-thickness-carcass-weight-and-body-weight-in-two-commercial-pig-populations
#15
Yuanmei Guo, Hengqing Qiu, Shijun Xiao, Zhenfang Wu, Ming Yang, Jie Yang, Jun Ren, Lusheng Huang
Growth and fatness traits are economically important in the pig industry. To dissect the genetic architecture of these traits in commercial pigs, we conducted a genome-wide association study (GWAS) for carcass weight, backfat thickness, and body weight in two commercial populations: Duroc × (Landrace × Yorkshire) (DLY) and Duroc populations. To enhance the detection power, three GWAS approaches including single-trait GWAS, multi-trait GWAS and meta-analysis were used in this study. A total of 13 suggestive loci were identified on nine chromosomes...
September 10, 2017: Journal of Applied Genetics
https://www.readbyqxmd.com/read/28888658/variations-in-glycoprotein-b-contribute-to-immunogenic-difference-between-prv-variant-js-2012-and-bartha-k61
#16
Zhi-Qing Yu, Wu Tong, Hao Zheng, Li-Wei Li, Guo-Xin Li, Fei Gao, Tao Wang, Chao Liang, Chao Ye, Ji-Qiang Wu, Qinfeng Huang, Guang-Zhi Tong
A newly emerged pseudorabies virus (PRV) variant has been identified in many Bartha-K61-vaccinated pig farms. This variant has caused great economic losses to the swine industry in China since 2011. Sequence analysis demonstrated that the gB gene of the emerging PRV variant JS-2012 had multiple variations compared with the vaccine strain Bartha-K61. In the study, a specific CRISPR/Cas9 system combined with homologous recombination was used to construct two recombinant viruses, BJB (Bartha-K61+JS-2012gB) and JBJ (JS-2012-ΔgE/gI+Bartha-K61gB), by interchanging the full-length gB genes between Bartha-K61 and JS-2012-ΔgE/gI...
September 2017: Veterinary Microbiology
https://www.readbyqxmd.com/read/28888647/fibronectin-fibrinogen-binding-protein-fbps-is-not-a-critical-virulence-factor-for-the-streptococcus-suis-serotype-2-strain-zy05719
#17
Quan Li, Yang Fu, Yanan He, Yuhang Zhang, Yunyun Qian, Yanfei Yu, Huochun Yao, Chengping Lu, Wei Zhang
Fibronectin-/fibrinogen-binding protein (FBPS) of Streptococcus suis serotype 2 (SS2) is an atypical anchorless microbial surface components recognizing adhesive matrix molecules (MSCRAMM) for which the role in bacterial infection are not clearly established. To investigate the biological functions of FBPS, an fbps knockout mutant was constructed in SS2 strain ZY05719 to explore the phenotypic changes between the wild-type and mutant strains. Cell morphology analyses combined with the basic growth curves showed that deletion of fbps does not significantly influence neither the thickness of the capsule of SS2 nor the cell growth characteristic...
September 2017: Veterinary Microbiology
https://www.readbyqxmd.com/read/28888639/increased-microbiome-diversity-at-the-time-of-infection-is-associated-with-improved-growth-rates-of-pigs-after-co-infection-with-porcine-reproductive-and-respiratory-syndrome-virus-prrsv-and-porcine-circovirus-type-2-pcv2
#18
Rebecca A Ober, James B Thissen, Crystal J Jaing, Ada G Cino-Ozuna, Raymond R R Rowland, Megan C Niederwerder
Porcine reproductive and respiratory syndrome virus (PRRSV) and porcine circovirus type 2 (PCV2) are two of the most important pathogens affecting the swine industry worldwide. Co-infections are common on a global scale, resulting in pork production losses through reducing weight gain and causing respiratory disease in growing pigs. Our initial work demonstrated that the fecal microbiome was associated with clinical outcome of pigs 70days post-infection (dpi) with PRRSV and PCV2. However, it remained uncertain if microbiome characteristics could predispose response to viral infection...
September 2017: Veterinary Microbiology
https://www.readbyqxmd.com/read/28887368/segment-specific-responses-of-intestinal-epithelium-transcriptome-to-in-feed-antibiotics-in-pigs
#19
Kaifan Yu, Chunlong Mu, Yuxiang Yang, Yong Su, Wei-Yun Zhu
Despite widespread use of antibiotics for treatment of human diseases and promotion of growth of agricultural animals, our understanding of their effects on the host is still very limited. We used a pig model fed with a cocktail of antibiotics or without, and found based on the denaturing gradient gel electrophoresis (DGGE) patterns that the fecal bacteria from the treatment and control animals were distinct. Furthermore, the total bacterial population in the feces tended to be decreased by the antibiotic treatment (P=0...
September 8, 2017: Physiological Genomics
https://www.readbyqxmd.com/read/28887157/effect-of-a-single-nucleotide-polymorphism-in-the-growth-hormone-secretagogue-receptor-ghsr-gene-on-growth-rate-in-pigs
#20
Bo Zhang, Peng Shang, Zhu Tao, Yangzong Qiangba, Zhixiu Wang, Hao Zhang
The growth hormone secretagogue receptor (GHSR) gene controls growth hormone (GH) release by inducing a strong stimulatory effect on the endogenous ligand, ghrelin. In this study, we examined the possible role of GHSR in the growth traits of four pig breeds, namely Tibetan pigs (n=45), Diannan small-eared pigs (n=40), Yorkshire pigs (n=45), and New Huai pigs (n=122). Single nucleotide polymorphisms (SNPs) in these pigs were identified by polymerase chain reaction (PCR) sequencing and genotyping was performed using PCR-restriction fragment length polymorphisms (PCR-RFLPs)...
November 15, 2017: Gene
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