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Pig growth

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https://www.readbyqxmd.com/read/28231264/precision-engineering-for-prrsv-resistance-in-pigs-macrophages-from-genome-edited-pigs-lacking-cd163-srcr5-domain-are-fully-resistant-to-both-prrsv-genotypes-while-maintaining-biological-function
#1
Christine Burkard, Simon G Lillico, Elizabeth Reid, Ben Jackson, Alan J Mileham, Tahar Ait-Ali, C Bruce A Whitelaw, Alan L Archibald
Porcine Reproductive and Respiratory Syndrome (PRRS) is a panzootic infectious disease of pigs, causing major economic losses to the world-wide pig industry. PRRS manifests differently in pigs of all ages but primarily causes late-term abortions and stillbirths in sows and respiratory disease in piglets. The causative agent of the disease is the positive-strand RNA PRRS virus (PRRSV). PRRSV has a narrow host cell tropism, limited to cells of the monocyte/macrophage lineage. CD163 has been described as a fusion receptor for PRRSV, whereby the scavenger receptor cysteine-rich domain 5 (SRCR5) region was shown to be an interaction site for the virus in vitro...
February 2017: PLoS Pathogens
https://www.readbyqxmd.com/read/28226409/effects-of-xylanase-supplementation-on-growth-performance-nutrient-digestibility-blood-parameters-fecal-microbiota-fecal-score-and-fecal-noxious-gas-emission-of-weaning-pigs-fed-corn-soybean-meal-based-diet
#2
Ruixia Lan, Tianshui Li, Inho Kim
This study was conducted to evaluate the effects of xylanase supplementation on nutrient digestibility, growth performance, blood parameters, fecal microflora shedding, fecal score and fecal noxious gas emission of weaning pigs fed corn-soybean meal based diet. A total of 150 weaning pigs with an average initial body weight (BW) of 7.85 ± 0.93 kg were randomly allocated to three treatments based on BW and sex (10 replicate pens with five pigs, two gilts and three barrows) were used in this 42-day trial...
February 22, 2017: Animal Science Journal, Nihon Chikusan Gakkaihō
https://www.readbyqxmd.com/read/28225810/correction-identification-of-genes-related-to-growth-and-lipid-deposition-from-transcriptome-profiles-of-pig-muscle-tissue
#3
Zhixiu Wang, Qinggang Li, Yangzom Chamba, Bo Zhang, Peng Shang, Hao Zhang, Changxin Wu
[This corrects the article DOI: 10.1371/journal.pone.0141138.].
2017: PloS One
https://www.readbyqxmd.com/read/28218810/phytosterols-improve-immunity-and-exert-anti-inflammatory-activity-in-weaned-piglets
#4
Qiaoling Hu, Zhuo Zhao, Shenglin Fang, Yiwei Zhang, Jie Feng
BACKGROUND: Phytosterols (PS), plant-derived natural steroid compounds, are novel feed additives to regulate immune function and promote pig growth. This study was conducted to determine the effects of PS on the immune response of weaned piglets. RESULTS: One hundred and twenty crossbred (Duroc × Landrace × Yorkshire) piglets with an average initial weight of 9.58 ± 0.26 kg were randomly allotted to three treatments. Treatments consisted of a control, PS (0...
February 20, 2017: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/28215673/supplement-of-cilostamide-in-growth-medium-improves-oocyte-maturation-and-developmental-competence-of-embryos-derived-from-small-antral-follicles-in-pigs
#5
Hanna Lee, Fazle Elahi, Joohyeong Lee, Seung Tae Lee, Sang-Hwan Hyun, Eunsong Lee
This study was conducted to evaluate the effects of cyclic AMP (cAMP) modulator cilostamide (CIL) and forskolin (FSK) treatment during in vitro growth (IVG) on growth, maturation, and embryonic development of cumulus-oocyte complexes (COCs) derived from small antral follicles < 3 mm in diameter (SAFCOCs). SAFCOCs were untreated (control) or treated with 20 μM CIL and/or 50 μM FSK for 2 days for IVG. Next, IVG oocytes were cultured for maturation and then induced for parthenogenesis (PA) or used as recipient ooplasts for somatic cell nuclear transfer (SCNT)...
March 15, 2017: Theriogenology
https://www.readbyqxmd.com/read/28215197/growth-responses-of-entire-and-immunocastrated-male-pigs-to-dietary-protein-with-and-without-ractopamine-hydrochloride
#6
T Needham, L C Hoffman, R M Gous
The interaction between dietary balanced protein, ractopamine (RAC) and Improvac (IMP) on the growth response of 120 individually penned male PIC© pigs was evaluated. The pigs entered the trial at 16 weeks of age and were assigned to 12 treatments using a 2×2×3 factorial design. Three balanced protein diets, formulated with standard illeal digestible lysine levels of 7.50 (low), 9.79 (medium) and 12.07 g/kg (high), were fed from 20 weeks. Improvac was administered at 16 and 20 weeks, the booster being given 4 weeks before slaughter...
February 20, 2017: Animal: An International Journal of Animal Bioscience
https://www.readbyqxmd.com/read/28213069/a-pilot-study-of-cell-mediated-gene-therapy-for-spinal-cord-injury-in-mini-pigs
#7
Islamov Rustem Robertovich, Sokolov Mikhail Evgenyevich, Bashirov Farid Vagizovich, Fadeev Filip Olegovich, Shmarov Maxim Michaylovich, Naroditskiy Boris Savelyevich, Povysheva Tatyana Vyacheslavovna, Shaymardanova Gulnara Ferdinantovna, Yakupov Radik Albertovich, Chelyshev Yuri Aleksandrovich, Lavrov Igor Aleksandrovich
Currently, in clinical practice there is no efficient way to overcome the sequences of neurodegeneration after spinal cord traumatic injury. Using a new experimental model of spinal cord contusion injury on miniature pigs, we proposed to deliver therapeutic genes encoding vascular endothelial growth factor (VEGF), glial cell line-derived neurotrophic factor (GDNF) and neural cell adhesion molecule (NCAM) to the damaged area, using umbilical cord blood mononuclear cells (UCBC). In this study, genetically engineered UCBC (2×10(6) cells in 200 ml of saline) were injected intrathecally to mini-pigs 10days after SCI...
February 14, 2017: Neuroscience Letters
https://www.readbyqxmd.com/read/28202293/therapeutic-hypothermia-attenuates-brain-edema-in-a-pig-model-of-cardiac-arrest-possible-role-of-the-angiopoietin-tie-2-system
#8
Jiebin Li, ChunSheng Li, Wei Yuan, JunYuan Wu, Jie Li, ZhenHua Li, YongZhen Zhao
OBJECTIVE: This study aimed to clarify whether therapeutic hypothermia protects against cerebral edema following cardiac arrest (CA) and cardiopulmonary resuscitation (CPR) in a porcine model via regulating the angiopoietin-Tie-2 ligand-receptor system. METHODS: Male pigs were randomized into the therapeutic hypothermia group, the normothermia group or the sham control group. CA was induced in pigs by untreated ventricular fibrillation for 8min. Brain edema was determined by measuring the cerebral cortical water content at 24h after the return of spontaneous circulation (ROSC)...
February 6, 2017: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28199379/the-effects-of-amoxicillin-treatment-of-newborn-piglets-on-the-prevalence-of-hernias-and-abscesses-growth-and-ampicillin-resistance-of-intestinal-coliform-bacteria-in-weaned-pigs
#9
Jinhyeon Yun, Satu Olkkola, Marja-Liisa Hänninen, Claudio Oliviero, Mari Heinonen
This study investigated the effects of a single amoxicillin treatment of newborn piglets on the prevalence of hernias and abscesses until the age of nine weeks. We also studied whether the treatment was associated with growth and mortality, the need for treatment of other diseases, the proportions of ampicillin resistant coliforms and antimicrobial resistance patterns of intestinal Escherichia coli (E. coli). A total of 7156 piglets, from approximately 480 litters, were divided into two treatment groups: ANT (N = 3661) and CON (N = 3495), where piglets were treated with or without a single intramuscular injection of 75 mg amoxicillin one day after birth, respectively...
2017: PloS One
https://www.readbyqxmd.com/read/28198616/comparison-of-metals-and-tetracycline-as-selective-agents-for-development-of-tetracycline-resistant-bacterial-communities-in-agricultural-soil
#10
Jianxiao Song, Christopher Rensing, Peter E Holm, Marko Virta, Kristian K Brandt
Environmental selection of antibiotic resistance may be caused by either antibiotic residues or coselecting agents. Using a strictly controlled experimental design, we compared the ability of metals (Cu or Zn) and tetracycline to (co)select for tetracycline resistance in bacterial communities. Soil microcosms were established by amending agricultural soil with known levels of Cu, Zn, or tetracycline known to represent commonly used metals and antibiotics for pig farming. Soil bacterial growth dynamics and bacterial community-level tetracycline resistance were determined using the [(3)H]leucine incorporation technique, whereas soil Cu, Zn, and tetracycline exposure were quantified by a panel of whole-cell bacterial bioreporters...
February 23, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/28196480/genome-wide-detection-of-genetic-markers-associated-with-growth-and-fatness-in-four-pig-populations-using-four-approaches
#11
Yuanmei Guo, Yixuan Huang, Lijuan Hou, Junwu Ma, Congying Chen, Huashui Ai, Lusheng Huang, Jun Ren
BACKGROUND: Genome-wide association studies (GWAS) have been extensively used to identify genomic regions associated with a variety of phenotypic traits in pigs. Until now, most GWAS have explored single-trait association models. Here, we conducted both single- and multi-trait GWAS and a meta-analysis for nine fatness and growth traits on 2004 pigs from four diverse populations, including a White Duroc × Erhualian F2 intercross population and Chinese Sutai, Laiwu and Erhualian populations...
February 14, 2017: Genetics, Selection, Evolution: GSE
https://www.readbyqxmd.com/read/28194111/syringa-oblata-lindl-aqueous-extract-is-a-potential-biofilm-inhibitor-in-s-suis
#12
Jingwen Bai, Yanbei Yang, Shuai Wang, Lingfei Gao, Jianqing Chen, Yongzhi Ren, Wenya Ding, Ishfaq Muhammad, Yanhua Li
Streptococcus suis (S. suis) is a zoonotic pathogen that causes severe disease symptoms in pigs and humans. Syringa oblata Lindl. distributed in the middle latitudes of Eurasia and North America were proved as the most development potential of Chinese Medicine. In this study, biofilm formation by S. suis decreased after growth with 1/2 MIC, 1/4 MIC, or 1/8 MIC of Syringa oblata Lindl. aqueous extract and rutin. Scanning electron microscopy analysis revealed the potential effect of Syringa oblata Lindl. aqueous extract and rutin against biofilm formation by S...
2017: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/28192175/increased-anxiety-like-phenotype-in-female-guinea-pigs-following-reduced-neurosteroid-exposure-in-utero
#13
Angela L Cumberland, Hannah K Palliser, Gabrielle K Crombie, David W Walker, Jonathan J Hirst
Neurosteroids are essential for aiding proper fetal neurodevelopment. Pregnancy compromises such as preterm birth, prenatal stress and intrauterine growth restriction are associated with an increased risk of developing behavioural and mood disorders, particularly during adolescence. These pathologies involve the premature loss or alteration of trophic steroid hormones reaching the fetus leading to impaired neurodevelopment. While the specific programming mechanisms are yet to be fully elucidated, in adult life, dysfunctions of allopregnanolone action are prevalent in individuals with depression, post-traumatic stress disorder and anxiety disorders...
February 9, 2017: International Journal of Developmental Neuroscience
https://www.readbyqxmd.com/read/28188339/microbial-composition-and-diversity-are-associated-with-plant-performance-a-case-study-on-long-term-fertilization-effect-on-wheat-growth-in-an-ultisol
#14
Lihua Li, Fenliang Fan, Alin Song, Chang Yin, Peiyuan Cui, Zhaojun Li, Yongchao Liang
The association between microbial communities and plant growth in long-term fertilization system has not been fully studied. In the present study, impacts of long-term fertilization have been determined on the size and activity of soil microbial communities and wheat performance in a red soil (Ultisol) collected from Qiyang Experimental Station, China. For this, different microbial communities originating from long-term fertilized pig manure (M), mineral fertilizer (NPK), pig manure plus mineral fertilizer (MNPK), and no fertilizer (CK) were used as inocula for the Ultisol tested...
February 10, 2017: Applied Microbiology and Biotechnology
https://www.readbyqxmd.com/read/28183860/diminished-satellite-cell-fusion-and-s6k1-expression-in-myotubes-derived-from-skeletal-muscle-of-low-birth-weight-neonatal-pigs
#15
Ying Chen, Haibo Zhu, Sydney R McCauley, Lidan Zhao, Sally E Johnson, Robert P Rhoads, Samer W El-Kadi
Low birth weight (LBWT) is consistently associated with impaired postnatal muscle growth in mammals. Satellite cell (SC)-mediated myonuclear incorporation precedes protein accumulation in the early stages of postnatal muscle development and growth. The objective of this study was to investigate proliferation and differentiation of SCs and the regulation of protein synthesis signaling in response to insulin-like growth factor (IGF)-I stimulation in SC-derived myotubes of LBWT neonatal pigs. SCs isolated from Longissimus dorsi muscle of LBWT and NBWT pigs (3-d-old, n = 8) were cultured and induced to proliferate and differentiate to myotubes in vitro...
February 2017: Physiological Reports
https://www.readbyqxmd.com/read/28183364/growth-of-total-fat-and-lean-and-of-primal-cuts-is-affected-by-the-sex-type
#16
A Carabús, R D Sainz, J W Oltjen, M Gispert, M Font-I-Furnols
Knowledge of tissue and cuts growth depending on the sex could be used to improve performance and efficiency. Computed tomography (CT) is a non-invasive technology that enables the study of the body composition of live animals during growth. The aims of the present study were (1) to evaluate variation in the body composition of four sex types (SEX) of pigs (castrated males (CM), immunocastrated males (IM), entire males (EM) and females (FE)) at the live weight of 30, 70, 100 and 120 kg, assessed using CT; (2) to model the growth of the main tissues and cuts; and (3) to predict the mature BW (MBW) of the four SEX and establish the relationships between the growth models and the MBW...
February 10, 2017: Animal: An International Journal of Animal Bioscience
https://www.readbyqxmd.com/read/28183169/effects-of-wheat-supplementation-levels-on-growth-performance-blood-profiles-nutrient-digestibility-and-pork-quality-in-growing-finishing-pigs
#17
Taehee Han, J S Hong, L H Fang, S H Do, B O Kim, Y Y Kim
Objective: This study was conducted to evaluate various wheat supplementation levels on growth performance, blood profiles, nutrient digestibility, and pork quality in growing-finishing pigs. Methods: A total of 120 growing pigs ([Yorkshire × Landrace] × Duroc), with an average 27.75 ± 1.319 kg body weight (BW), were used in growth trial. Pigs were allotted into each treatment by body weight and sex in 4 replicates with 6 pigs per pen in a randomized complete block (RCB) design...
February 1, 2017: Asian-Australasian Journal of Animal Sciences
https://www.readbyqxmd.com/read/28183153/effects-of-armillariella-tabescens-mycelia-on-the-growth-performance-and-intestinal-immune-response-and-microflora-of-early-weaned-pigs
#18
Wen-Bin Chen, Mao-Ji Cheng, Yun-Bo Tian, Qin-Hua Wang, Bing Wang, Mei-Jun Li, Re-Jun Fang
This study was performed to evaluate effects of Armillariella tabescens (A. tabescens) on the growth performance and intestinal immune response and microflora in early-weaned pigs when used as feed additive. A. tabescens mycelia were added to basal diets at concentrations of 0%, 0.1%, 0.3% or 0.9% (w/w). A total of 144 commercial cross-bred piglets were randomly allocated to one of these four diets and fed for 30 days. The growth performance of early-weaned piglets displayed improvement with diets containing 0...
February 9, 2017: Animal Science Journal, Nihon Chikusan Gakkaihō
https://www.readbyqxmd.com/read/28183149/long-non-coding-rna-analysis-of-muscular-responses-to-testosterone-deficiency-in-huainan-male-pigs
#19
Baosong Xing, Xianxiao Bai, Hongxia Guo, Junfeng Chen, Liushuai Hua, Jiaqing Zhang, Qiang Ma, Qiaoling Ren, Huashuai Wang, Jing Wang
Long non-coding RNAs (lncRNAs) participated in growth and development of skeletal muscle; however, little is known about their response to testosterone deficiency in porcine skeletal muscle. We compared lean mass related carcass traits and lncRNAs expression files in Longissimus dorsi (LD) muscle between intact and castrated Huainan male pigs. The results showed that castration significantly reduced eye muscle area and lean meat percentage (P < 0.05), but increased the fat mass weight (P < 0.05). Meanwhile, 8946 lncRNAs, including 6743 intergenic lncRNAs (lincRNAs), 498 anti-sense lncRNAs, and 1705 intronic lncRNAs, were identified in porcine LD, among which, 385 lncRNAs were considered as the differentially expressed candidates between intact groups and castrated groups (q-value < 0...
February 9, 2017: Animal Science Journal, Nihon Chikusan Gakkaihō
https://www.readbyqxmd.com/read/28178968/imatinib-relaxes-the-pulmonary-venous-bed-of-guinea-pigs
#20
Nina A Maihöfer, Said Suleiman, Daniela Dreymüller, Paul W Manley, Rolf Rossaint, Stefan Uhlig, Christian Martin, Annette D Rieg
BACKGROUND: Recently, the IMPRES study revealed that systemic imatinib improves exercise capacity in patients with advanced pulmonary arterial hypertension. Imatinib blocks the tyrosine kinase activity of the platelet-derived growth factor (PDGF)-receptor (PDGFR), acts antiproliferative and relaxes pulmonary arteries. However so far, the relaxant effects of imatinib on pulmonary veins (PVs) and on the postcapillary resistance are unknown, although pulmonary hypertension (PH) due to left heart disease (LHD) is most common and primarily affects PVs...
February 8, 2017: Respiratory Research
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