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https://www.readbyqxmd.com/read/28631826/effects-of-dietary-supplementation-of-red-pepper-schinus-terebinthifolius-raddi-essential-oil-on-performance-small-intestinal-morphology-and-microbial-counts-of-weanling-pigs
#1
Pedro Leon Gomes Cairo, Franz Dias Gois, Maicon Sbardella, Hebert Silveira, Roberto Maciel de Oliveira, Ivan Bezerra Allaman, Vinicius Souza Cantarelli, Leandro Batista Costa
BACKGROUND: Many strategies have been developed to improve intestinal health and performance of newly weaned piglets as the antibiotic growth promoters. Natural products such as essential oils have been scientifically recognized as growth enhancer feed additives for weanling pigs, replacing the antibiotics. Therefore, it has been hypothesized that Brazilian red pepper could replace performance-enhancing antibiotics also in weanling pig diets. However, one experiment was conducted to determine the effects of dietary Brazilian red pepper essential oil or antimicrobial growth promoter on intestinal health and growth performance of weanling pigs...
June 20, 2017: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/28631587/dietary-supplementation-with-a-nucleotide-rich-yeast-extract-modulates-gut-immune-response-and-microflora-in-weaned-pigs-in-response-to-a-sanitary-challenge
#2
S M Waititu, F Yin, R Patterson, A Yitbarek, J C Rodriguez-Lecompte, C M Nyachoti
An experiment was carried out to evaluate the short-term effect of supplementing a nucleotide-rich yeast extract (NRYE) on growth performance, gut structure, immunity and microflora of piglets raised under sanitary and unsanitary conditions. A total of 84, 21-day old piglets were used in this study; 42 piglets were raised in a room designated as the clean room that was washed once per week, whereas the other 42 piglets were raised in a room designated as the unclean room in which 7 kg of manure from the sow herd was spread on each pen floor on day 1 and 7 and the room was not washed throughout the experiment...
June 20, 2017: Animal: An International Journal of Animal Bioscience
https://www.readbyqxmd.com/read/28631185/the-increased-expression-of-follicle-stimulating-hormone-leads-to-a-decrease-of-fecundity-in-transgenic-large-white-female-pigs
#3
Kai Jiang, Pan Xu, Wanbo Li, Qiang Yang, Longyun Li, Chuanmin Qiao, Huanfa Gong, Hao Zheng, Zhimin Zhou, Hao Fu, Qiuyan Li, Yuyun Xing, Jun Ren
Follicle-stimulating hormone (FSH) is a pituitary gonadotropin regulating reproduction in mammals. Overexpression of the exogenous FSHα/β genes from Chinese Erhualian pigs improved female fecundity of transgenic (TG) mice and male spermatogenesis ability of Large White TG boars. Here, we investigated the impact of the exogenous FSHα/β genes on female reproductive performance of Large White TG pigs. First, we identified the integration site of the exogenous FSHα/β genes at 140,646,456 bp on chromosome 9 in these TG pigs using whole-genome sequencing...
June 19, 2017: Transgenic Research
https://www.readbyqxmd.com/read/28629420/comparison-of-the-effects-of-platelet-rich-or-growth-factor-rich-plasma-on-intestinal-anastomosis-healing-in-pigs
#4
Gessica Giusto, Cristina Vercelli, Selina Iussich, Massimiliano Tursi, Giovanni Perona, Marco Gandini
BACKGROUND: The use of autologous platelet-rich plasma (PRP) and plasma rich in growth factors (PRGF) has been proposed for the treatment of several acute and chronic syndromes, such as corneal epithelial defects and dry eye syndrome, gum bleeding during oral surgery, and in orthopaedic surgery. We hypothesized that PRGF, rather than PRP, could be more effective because of its intrinsic characteristics in promoting the healing of intestinal anastomosis. The purpose of the present study was to evaluate and compare the effects of PRP and PRGF on various parameters of anastomotic healing in a swine model...
June 19, 2017: BMC Veterinary Research
https://www.readbyqxmd.com/read/28628266/embryo-maternal-dialogue-during-pregnancy-establishment-and-implantation-in-the-pig
#5
REVIEW
Agnieszka Waclawik, Monika M Kaczmarek, Agnieszka Blitek, Piotr Kaczynski, Adam J Ziecik
Porcine conceptuses secrete pregnancy-recognition signals (estrogens, including estradiol-17β) that inhibit luteolysis, thereby prolonging progesterone production by corpora lutea. The supportive mechanism by which the conceptus also inhibits luteolysis is by shifting endometrial prostaglandin (PG) synthesis to luteoprotective PGE2. Progesterone stimulates endometrial production of factors that are essential for conceptus development. Priming the uterus by progesterone and loss of progesterone receptors from the uterine epithelium by D1ay 10-12 after estrus are key for achieving endometrial receptivity for implantation...
June 19, 2017: Molecular Reproduction and Development
https://www.readbyqxmd.com/read/28623308/improved-growth-patterns-in-cystic-fibrosis-mice-after-loss-of-histone-deacetylase-6
#6
Sharon M Rymut, Deborah A Corey, Dana M Valerio, Bernadette O Erokwu, Chris A Flask, Thomas J Kelley, Craig A Hodges
Growth failure in cystic fibrosis (CF) patients has been well-documented and shown to correlate with poorer disease outcomes. This observation is also true in CF animal models, including mouse, pig, rat, and ferret. The etiology underlying growth deficits is unknown, and our previous work demonstrated reduced tubulin acetylation in CF cell models and tissue that is correctable by inhibition of histone deacetylase-6 (HDAC6). Here, we hypothesize that loss of HDAC6 will improve growth phenotype in a CF mouse model...
June 16, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28620056/postnatal-airway-growth-in-cystic-fibrosis-piglets
#7
Ryan J Adam, Mahmoud H Abou Alaiwa, Drake C Bouzek, Daniel P Cook, Nicholas D Gansemer, Peter J Taft, Linda S Powers, Mallory R Stroik, Mark J Hoegger, James D McMenimen, Eric A Hoffman, Joseph Zabner, Michael J Welsh, David K Meyerholz, David A Stoltz
Mutations in the gene encoding the cystic fibrosis transmembrane conductance regulator (CFTR) anion channel cause cystic fibrosis (CF). The leading cause of death in the CF population is lung disease. Increasing evidence suggests that in utero airway development is CFTR-dependent and that developmental abnormalities may contribute to CF lung disease. However, relatively little is known of postnatal CF airway growth, largely because such studies are limited in people. Therefore, we examined airway growth and lung volume in a porcine model of CF...
June 15, 2017: Journal of Applied Physiology
https://www.readbyqxmd.com/read/28619154/an-unusual-culprit-klebsiella-pneumoniae-causing-septicaemia-outbreaks-in-neonatal-pigs
#8
Bethany G Bowring, V Anthony Fahy, Andrew Morris, Alison M Collins
This study investigated the cause of recent outbreaks of septicaemia in neonatal pigs in Australia (Victoria and Queensland). Septicaemia in neonatal pigs is commonly caused by enterotoxigenic E. coli, extraintestinal pathogenic E. coli and beta-haemolytic streptococci. Infrequent causes of septicaemia are Actinobacillus suis and Citrobacter freundii. Therefore, it was quite unexpected when Klebsiella pneumoniae was isolated in predominant growth from multiple organs of pigs dying of septicaemia from six days of age...
May 2017: Veterinary Microbiology
https://www.readbyqxmd.com/read/28612173/evaluation-of-the-feeding-value-of-dichrostachys-cinerea-pods-for-fattening-pigs-in-cuba
#9
N Martín-Casas, M Reinoso-Pérez, J R García-Díaz, H H Hansen, M O Nielsen
Dichrostachys cinerea (L.) Wight & Arn. is a tropical leguminous shrub widely regarded as an invasive species in Cuba, after having invaded a significant proportion of its arable land during the past decades. Concurrently, smallholder pig producers are highly constrained by the scarcity of protein feeds. This study aimed to assess the feeding value of D. cinerea pod meal (DCPM) as an alternative protein supplement for pigs in Cuban smallholder production systems. An on-farm feeding trial was carried out with three groups (N = 10) of growing-fattening pigs over 60 days, where DCPM replaced 0, 15, and 30% in DM of a dietary commercial concentrate...
June 13, 2017: Tropical Animal Health and Production
https://www.readbyqxmd.com/read/28610885/three-dimensional-printed-bioengineered-tracheal-grafts-preclinical-results-and-potential-for-human-use
#10
Sadiq S Rehmani, Adnan M Al-Ayoubi, Adil Ayub, Michael Barsky, Erik Lewis, Raja Flores, Robert Lebovics, Faiz Y Bhora
BACKGROUND: We aimed to develop a process using three-dimensional (3D) printing to create bioengineered tracheal grafts (BETGs) for reconstruction of anterior tracheal defects in a large-animal model (porcine) that would have translational relevance for potential human use. METHODS: Preoperative computed tomographic scans were used to create virtual 3D models of the animal airways. Anatomically scaled tracheal grafts were subsequently developed using 3D-printed polycaprolactone and extracellular matrix...
June 11, 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/28609185/discovery-and-preclinical-development-of-netarsudil-a-novel-ocular-hypotensive-agent-for-the-treatment-of-glaucoma
#11
Cheng-Wen Lin, Bryan Sherman, Lori A Moore, Carmen L Laethem, Da-Wen Lu, Padmanabhan P Pattabiraman, Ponugoti Vasantha Rao, Mitchell A deLong, Casey C Kopczynski
PURPOSE: Rho-associated protein kinase (ROCK) inhibitors lower intraocular pressure (IOP) by increasing aqueous outflow through the trabecular meshwork (TM). The preclinical characterization of netarsudil, a new ROCK/norepinephrine transporter (NET) inhibitor currently in clinical development, is presented herein. METHODS: The kinase inhibitory activity of netarsudil was compared to its esterase metabolite, netarsudil-M1, and 3 other ROCK inhibitors using a commercially available kinase assay kit...
June 13, 2017: Journal of Ocular Pharmacology and Therapeutics
https://www.readbyqxmd.com/read/28604785/genome-wide-association-analysis-and-functional-annotation-of-positional-candidate-genes-for-feed-conversion-efficiency-and-growth-rate-in-pigs
#12
Justyna Horodyska, Ruth M Hamill, Patrick F Varley, Henry Reyer, Klaus Wimmers
Feed conversion efficiency is a measure of how well an animal converts feed into live weight and it is typically expressed as feed conversion ratio (FCR). FCR and related traits like growth rate (e.g. days to 110 kg-D110) are of high interest for animal breeders, farmers and society due to implications on animal performance, feeding costs and environmental sustainability. The objective of this study was to identify genomic regions associated with FCR and D110 in pigs. A total of 952 terminal line boars, showing an individual variation in FCR, were genotyped using 60K SNP-Chips...
2017: PloS One
https://www.readbyqxmd.com/read/28600895/metabolic-modeling-of-energy-balances-in-mycoplasma-hyopneumoniae-shows-that-pyruvate-addition-increases-growth-rate
#13
Tjerko Kamminga, Simen-Jan Slagman, Jetta J E Bijlsma, Vitor A P Martins Dos Santos, Maria Suarez-Diez, Peter J Schaap
Mycoplasma hyopneumoniae is cultured on large-scale to produce antigen for inactivated whole-cell vaccines against respiratory disease in pigs. However, the fastidious nutrient requirements of this minimal bacterium and the low growth rate make it challenging to reach sufficient biomass yield for antigen production. In this study, we sequenced the genome of M. hyopneumoniae strain 11 and constructed a high quality constraint-based genome-scale metabolic model of 284 chemical reactions and 298 metabolites. We validated the model with time-series data of duplicate fermentation cultures to aim for an integrated model describing the dynamic profiles measured in fermentations...
June 10, 2017: Biotechnology and Bioengineering
https://www.readbyqxmd.com/read/28597956/a-post-gwas-confirming-gpat3-gene-associated-with-pig-growth-and-a-significant-snp-influencing-its-promoter-activity
#14
Kejun Wang, Yufang Liu, Qiao Xu, Chengkun Liu, Jve Wang, Cui Ding, Meiying Fang
Our previous genome-wide association study revealed that a SNP, ASGA0040372, located upstream of glycerol-3-phosphate acyltransferase 3 (GPAT3), is related to growth traits in Duroc pigs. In this study, we aimed to extensively investigate the genetic variation of GPAT3 and to further verify the contribution of ASGA0040372 to growth traits and its effect on promoter activity. Our data, obtained based on gene cloning and rapid amplification of cDNA ends experiments, showed that there are 14 exons and three alternative splicing variants...
June 9, 2017: Animal Genetics
https://www.readbyqxmd.com/read/28595834/the-completely-annotated-genome-and-comparative-genomics-of-the-peptoniphilaceae-bacterium-str-ing2-d1g-a-novel-acidogenic-bacterium-isolated-from-a-mesophilic-biogas-reactor
#15
Geizecler Tomazetto, Sarah Hahnke, Thomas Langer, Daniel Wibberg, Jochen Blom, Irena Maus, Alfred Pühler, Michael Klocke, Andreas Schlüter
The strictly anaerobic Peptoniphilaceae bacterium str. ING2-D1G (=DSM 28672=LMG 28300) was isolated from a mesophilic laboratory-scale completely stirred tank biogas reactor (CSTR) continuously co-digesting maize silage, pig and cattle manure. Based on 16S rRNA gene sequence comparison, the closest described relative to this strain is Peptoniphilus obesi ph1 showing 91.2% gene sequence identity, the most closely related species with a validly published name is Peptoniphilus indolicus DSM 20464(T) whose 16S rRNA gene sequence is 90...
June 5, 2017: Journal of Biotechnology
https://www.readbyqxmd.com/read/28594948/easy-and-non-invasive-disease-detection-in-pigs-by-adenosine-deaminase-activity-determinations-in-saliva
#16
Ana María Gutiérrez, Ernesto De La Cruz-Sánchez, Ana Montes, Juan Sotillo, Cándido Gutiérrez-Panizo, Pablo Fuentes, Pedro Luis Tornel, Juan Cabezas-Herrera
The quantification of adenosine deaminase (ADA) in porcine saliva samples has been analyzed for its use as a marker of disease. First, an analytical validation of the enzymatic assay used for ADA measurements was performed. Afterwards, saliva samples were collected from 50 healthy animals and 64 animals with different symptoms of disease, which were divided into local inflammation, gastrointestinal disorder, respiratory disorder and growth retardation. To optimize ADA measurements, total ADA (tADA), specific ADA (sADA) and ADA isoforms 1 and 2 activities were calculated...
2017: PloS One
https://www.readbyqxmd.com/read/28594446/sow-housing-associated-with-reproductive-performance-in-breeding-herds
#17
REVIEW
Yuzo Koketsu, Ryosuke Iida
Female pigs in breeding herds can be managed through four phases-gilt development, breeding, gestation, and lactation-during which they may be housed in group or individual pens, stalls, or on pasture. In this review, we focus on housing environments that optimize outcomes during gestation and lactation. Appropriate housing is important during early gestation, to protect embryos and to confirm pregnancy, and from mid-to-late gestation, to ensure sufficient nutrition to increase placental and fetal growth. No difference in the number of pigs born alive were reported between group housing and individual stall housing, although more risk factors for reproductive performance are associated with group housing than stall housing including genetics, bedding, floor space allowance, group size, social ranking, and parity...
May 2, 2017: Molecular Reproduction and Development
https://www.readbyqxmd.com/read/28593444/efficacy-of-dietary-supplementation-of-fatty-acid-compound-on-performance-and-production-in-finishing-pigs
#18
Santi Devi Upadhaya, Hyeok Min Yun, Shuaiqi Huang, In Ho Kim
The present study was conducted to evaluate the efficacy of dietary supplementation of 0.5 and 1% of fatty acid (FA) compound containing conjugated linoleic acid as active component on growth performance, apparent nutrient digestibility, serum lipid profile, meat quality, and fatty acid profiles in muscle and adipose tissue in finishing pigs. A total of 90 finishing pigs ([Yorkshire × Landrace] × Duroc) were used in 5-week trial. The growth performance and nutrient digestibility were unaffected with FA supplementation...
June 8, 2017: Tropical Animal Health and Production
https://www.readbyqxmd.com/read/28592484/analysis-of-neointima-development-in-flow-diverters-using-optical-coherence-tomography-imaging
#19
Yoshikazu Matsuda, Joonho Chung, Demetrius K Lopes
BACKGROUND: Flow diverters are used for the treatment of intracranial aneurysms. Surface modification may decrease the thrombogenicity of flow diverters but the details are unknown. Optical coherence tomography (OCT) is an intravascular imaging test with high resolution which identifies neointimal growth over stents. We compared the development of neointima in a flow diverter and stents with and without surface modification in a swine model. METHODS: In this study we implanted four devices (two in each carotid artery) in four pigs...
June 7, 2017: Journal of Neurointerventional Surgery
https://www.readbyqxmd.com/read/28592312/vertical-bone-regeneration-using-rhbmp-2-and-vegf
#20
Lara Schorn, Christoph Sproll, Michelle Ommerborn, Christian Naujoks, Norbert R Kübler, Rita Depprich
BACKGROUND: Sufficient vertical and lateral bone supply and a competent osteogenic healing process are prerequisities for the successful osseointegration of dental implants in the alveolar bone. Several techniques including autologous bone grafts and guided bone regeneration are applied to improve quality and quantity of bone at the implantation site. Depending on the amount of lacking bone one- or two-stage procedures are required. Vertical bone augmentation has proven to be a challenge particularly in terms of bone volume stability...
June 7, 2017: Head & Face Medicine
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