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https://www.readbyqxmd.com/read/28529126/l-a-ratio-insulin-resistance-and-metabolic-risk-in-women-with-polycystic-ovarian-syndrome
#1
Vandana Gupta, Supriya Mishra, Sameeksha Mishra, Vani Gupta
BACKGROUND AND AIMS: The plasma leptin-adiponectin ratio (L:A) has been suggested as a one of the potentially independent predictor of metabolic risk and Insulin resistance in women with polycystic ovarian syndrome (PCOS). METHODS: This is a case-control study, total 439 female subjects, comprises in to two group 223 cases (PCOS) and 216 control (non-PCOS women) according to their clinical characteristics. Further both case and control group were sub-grouped in PCOS and non-PCOS with metabolic syndrome (wMetS) and without metabolic syndrome (woMetS) as per National Cholesterol Education Program Treatment Panel (NCEPATP) guidelines...
May 10, 2017: Diabetes & Metabolic Syndrome
https://www.readbyqxmd.com/read/28508856/microvascular-complications-of-type-2-diabetes-mellitus-are-associated-with-plaque-score-in-the-carotid-arteries
#2
Wojciech Bartman, Katarzyna Nabrdalik, Hanna Kwiendacz, Tomasz Sawczyn, Andrzej Tomasik, Krystyna Pierzchała, Monika Adamczyk-Sowa, Agnieszka Machowska-Majchrzak, Beata Łabuz-Roszak, Władysław Grzeszczak, Janusz Gumprecht
INTRODUCTION    The "common soil" hypothesis suggests that diabetic micro- and macroangiopathy arise from a similar pathophysiological has been once proposed. It is well documented that carotid artery atherosclerosis in patients with type 2 diabetes mellitus (T2DM) is associated with cardiovascular complications; however, whether microvascular complications are similarly related remains unclear. OBJECTIVES    We aimed to explore whether plaque score or common carotid artery intima-media thickness (CIMT) is associated with the macroangiopathic or microangiopathic complications of T2DM...
May 16, 2017: Polish Archives of Internal Medicine
https://www.readbyqxmd.com/read/28501922/sepp1-polymorphisms-modulate-serum-glucose-and-lipid-response-to-brazil-nut-supplementation
#3
Janaina L S Donadio, Marcelo M Rogero, Elvira M Guerra-Shinohara, Charles Desmarchelier, Patrick Borel, Silvia M F Cozzolino
PURPOSE: The consumption of Brazil nuts has been associated with benefits to lipid metabolism and reductions in total cholesterol and LDL concentrations. They are the richest natural source of selenium which has essential functions in human physiology. Genetic polymorphisms in Selenoprotein P could impair lipid and glucose metabolisms. The aim of this work was to verify the influence of polymorphisms in genes for selenoproteins on blood lipid levels after dietary supplementation with Brazil nuts in healthy adults...
May 13, 2017: European Journal of Nutrition
https://www.readbyqxmd.com/read/28494135/prospective-association-between-body-mass-index-at-midlife-and-healthy-aging-among-french-adults
#4
Indunil Ruhunuhewa, Moufidath Adjibade, Valentina A Andreeva, Pilar Galan, Serge Hercberg, Karen E Assmann, Emmanuelle Kesse-Guyot
OBJECTIVE: To assess the association between midlife body mass index (BMI) and healthy aging (HA) in the French SU.VI.MAX cohort. METHODS: HA was assessed in 2007 to 2009 among 2,733 individuals, aged 45 to 60 years and free of diabetes, cardiovascular disease and cancer at baseline (1994-1995). HA was defined as not developing any major chronic disease, good physical and cognitive functioning, no limitations in instrumental activities of daily living, no depressive symptoms, no health-related limitations in social life, good overall self-perceived health, and no function-limiting pain...
May 11, 2017: Obesity
https://www.readbyqxmd.com/read/28493240/does-vitamin-d-status-correlate-with-cardiometabolic-risk-factors-in-adults-with-growth-hormone-deficiency
#5
Ivayla Uzunova, Georgi Kirilov, Sabina Zacharieva, Naydenka Zlatareva, Krasimir Kalinov
Apart from being individually associated with cardiometabolic health, 25(OH)D and IGF-1 interplay with a positive correlation between them, which raises questions about the role of vitamin D for the adverse cardiovascular (CV) risk profile in hyposomatotropism. Thus, we aimed to investigate vitamin D status in GH deficiency (GHD) and the association between 25(OH)D and metabolic syndrome (MetS), its components, and other surrogate markers of CV risk. A total of 129 GHD adults (childhood-onset GHD, 41.9%) underwent blood testing (glucose, insulin, lipid profile, uric acid); blood pressure, anthropometric and bioelectrical-impedance measurements...
May 10, 2017: Hormone and Metabolic Research, Hormon- und Stoffwechselforschung, Hormones et Métabolisme
https://www.readbyqxmd.com/read/28489766/sex-difference-determined-the-role-of-sex-hormone-binding-globulin-in-obese-children-during-short-term-weight-reduction-program
#6
Fu-Min Wang, Chien-Ming Lin, Shao-Hung Lien, Li-Wei Wu, Ching-Feng Huang, Der-Ming Chu
The relationship between hyperinsulinemia and decreased sex hormone-binding globulin (SHBG) levels has been observed in obese adults and children. Weight reduction not only increased insulin sensitivity but also elevated serum SHBG levels in obese adults and children. However, the correlation between the changes in insulin resistance indices and serum SHBG concentration during weight reduction program (WRP) is not fully understood, particularly in obese children. This study is to evaluate whether SHBG level is a potential biomarker that can be used to assess insulin resistance in obese children during a short-term WRP...
May 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28489465/effects-of-phototherapy-plus-physical-training-on-metabolic-profile-and-quality-of-life-in-postmenopausal-women
#7
Fernanda Rossi Paolillo, Audrey Borghi-Silva, Ross Arena, Nivaldo Antonio Parizotto, Cristina Kurachi, Vanderlei Salvador Bagnato
A cluster of metabolic abnormalities are markedly higher among postmenopausal women. The present study evaluated the effects of infrared-light-emitting diode (LED) during treadmill training on multiple metabolic markers, body fat, dietary habits and quality of life in postmenopausal women. Forty five postmenopausal women aged 50 to 60 years were randomly assigned to one of three groups; thirty women successfully completed the full study. The three groups were: (i) the LED group, which performed treadmill training associated with phototherapy (n=10); (ii) the exercise group, which carried out treadmill training only (n=10) and; (iii) the sedentary group, which neither performed physical training nor underwent phototherapy (n=10)...
May 10, 2017: Journal of Cosmetic and Laser Therapy: Official Publication of the European Society for Laser Dermatology
https://www.readbyqxmd.com/read/28487551/high-free-androgen-index-is-associated-with-increased-risk-of-non-alcoholic-fatty-liver-disease-in-women-with-polycystic-ovary-syndrome-independently-of-obesity-and-insulin-resistance
#8
C Jie, W Chunhua, Z Yi, W Yuying, X Wendi, L Tzuchun, L Shengxian, W Lihua, Z Jun, S Yun, L Wei, T Tao
BACKGROUND/OBJECTIVECentral obesity and insulin resistance are common conditions in women with PCOS and in subjects with non-alcoholic fatty liver disease (NAFLD). However, few studies have addressed the association between hyperandrogenism (HA) and NAFLD. We aimed to determine whether variations in the free androgen index (FAI) might be associated with NAFLD prevalence.SUBJECTS/METHODSA cross-sectional study was performed including 400 Chinese women with PCOS and 100 age and body mass index (BMI)-matched women...
May 10, 2017: International Journal of Obesity: Journal of the International Association for the Study of Obesity
https://www.readbyqxmd.com/read/28486003/placental-lipoprotein-lipase-dna-methylation-alterations-are-associated-with-gestational-diabetes-and-body-composition-at-5%C3%A2-years-of-age
#9
Valérie Gagné-Ouellet, Andrée-Anne Houde, Simon-Pierre Guay, Patrice Perron, Daniel Gaudet, Renée Guérin, Jean-Patrice Baillargeon, Marie-France Hivert, Diane Brisson, Luigi Bouchard
Gestational diabetes mellitus (GDM) is associated with obesity in childhood. This suggests that consequences of in utero exposure to maternal hyperglycemia extend beyond the fetal development, possibly through epigenetic programming. The aims of this study were to assess whether placental DNA methylation (DNAm) marks were associated with maternal GDM status and to offspring body composition at 5 years old in a prospective birth cohort. DNAm levels were measured in the fetal side of the placenta in 66 samples (24 from GDM mothers) using bisDNA-pyrosequencing...
May 9, 2017: Epigenetics: Official Journal of the DNA Methylation Society
https://www.readbyqxmd.com/read/28481997/patterns-of-growth-body-composition-and-lipid-profiles-in-a-south-african-cohort-of-human-immunodeficiency-virus-infected-and-uninfected-children-a-cross-sectional-study
#10
Sarah M Ramteke, Stephanie Shiau, Marc Foca, Renate Strehlau, Francoise Pinillos, Faeezah Patel, Avy Violari, Afaaf Liberty, Ashraf Coovadia, Louise Kuhn, Stephen M Arpadi
Background.: Prior research in sub-Saharan Africa reports dyslipidemia in perinatally human immunodeficiency virus (HIV)-infected children receiving ritonavir-boosted lopinavir (LPV/r) compared with efavirenz; however, interpretation of findings is limited by lack of comparison data from HIV-uninfected children. Methods.: We conducted a cross-sectional analysis of lipid profiles and growth within a larger longitudinal cohort study of perinatally HIV-infected and HIV-uninfected children aged 4-9 years in Johannesburg, South Africa...
May 6, 2017: Journal of the Pediatric Infectious Diseases Society
https://www.readbyqxmd.com/read/28479481/a-shared-biomechanical-environment-for-bone-and-posture-development-in-children
#11
Fábio A Araújo, Ana Martins, Nuno Alegrete, Laura D Howe, Raquel Lucas
BACKGROUND CONTEXT: In each specific habitual standing posture, gravitational forces determine the mechanical setting provided to skeletal structures. Bone quality and resistance to physical stress is highly determined by habitual mechanical stimulation. However, the relationship between bone properties and sagittal posture has never been studied in children. PURPOSE: To investigate the association between bone physical properties and sagittal standing postural patterns in 7-year-old children...
May 4, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28476520/distinctive-metabolomic-fingerprint-in-scleroderma-patients-with-pulmonary-arterial-hypertension
#12
Martino Deidda, Cristina Piras, Christian Cadeddu Dessalvi, Emanuela Locci, Luigi Barberini, Susanne Orofino, Mario Musu, Mario Nicola Mura, Paolo Emilio Manconi, Gabriele Finco, Luigi Atzori, Giuseppe Mercuro
BACKGROUND: Pulmonary arterial hypertension (PAH) in systemic sclerosis (SS) identifies a poor prognosis subset of patients. Recent studies suggested a "metabolic theory" on the development of pulmonary arterial hypertension. On this basis we performed a metabolomic study in order to evaluate whether differences in pulmonary arterial blood metabolites were identifiable in SS patients with increased pulmonary vascular resistance (PVR). METHODS: We studied 18 SS patients (age 58...
April 19, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28467510/prevalence-and-determinants-of-chronic-kidney-disease-in-northeast-of-iran-results-of-the-golestan-cohort-study
#13
Sadaf G Sepanlou, Hamid Barahimi, Iraj Najafi, Farin Kamangar, Hossein Poustchi, Ramin Shakeri, Monir Sadat Hakemi, Akram Pourshams, Masoud Khoshnia, Abdolsamad Gharravi, Behrooz Broumand, Ali Nobakht-Haghighi, Kamyar Kalantar-Zadeh, Reza Malekzadeh
BACKGROUND: The burden of chronic kidney disease (CKD) is increasing globally in particular in fast emerging economies such as Iran. Population-based studies on prevalence of CKD in Iran are scarce. The objective of the current study was to explore the prevalence and determinants of CKD in the setting of Golestan Cohort Study (GCS), the largest prospective cohort in the Middle East. METHODS: In this observational study, 11,409 participants enrolled in the second phase of GCS were included...
2017: PloS One
https://www.readbyqxmd.com/read/28462576/world-and-olympic-mountain-bike-champions-anthropometry-body-composition-and-somatotype
#14
Cristóbal Sánchez-Muñoz, José J Muros, Mikel Zabala
BACKGROUND: The aim of the study was to describe the anthropometric profile of male Olympic cross country (XCO) mountain bikers. METHODS: Fifty one XCO bikers participated in this study, divided into an elite group who competed in top level international competitions, and a non-elite group who competed at a national level. The elite group was further classified according to whether they had been world or Olympic champion mountain bikers (WOC) or not (NWOC). The anthropometric profiles included the measurements of height, weight, arm span, skinfolds, girths, and breadths...
April 28, 2017: Journal of Sports Medicine and Physical Fitness
https://www.readbyqxmd.com/read/28459314/anthropometric-profiles-of-elite-open-water-swimmers
#15
Gregory Shaw, Iñigo Mujika
Reports detailing the physiques of open water (OW) swimmers are limited. Data from anthropometric screening around competition provides a unique opportunity to describe the current physique attributes of elite OW swimmers peaking for international competition. Anthropometric screening was undertaken on a group of Australian and French OW swimmers as part of performance monitoring within 2 weeks of the 2015 FINA World Championships. Height, mass, and sum of seven skinfolds was measured utilising ISAK standardised measurement techniques by two trained anthropometrists...
May 1, 2017: International Journal of Sports Physiology and Performance
https://www.readbyqxmd.com/read/28459290/injury-patterns-physiological-profile-and-performance-in-university-rugby-union
#16
Shane Ball, Mark Halaki, Tristan Sharp, Rhonda Orr
OBJECTIVES: Rugby union is a physically demanding collision sport with high injury rates. There is a common perception that higher training loads result in greater injury risk in field-based sports. This study aims to determine injury, anthropometric and physical performance characteristics in junior rugby union players and investigate the interaction between training load and injury across a competitive season. DESIGN: Prospective cohort study. METHODS: Fifty-one players (age 19...
May 1, 2017: International Journal of Sports Physiology and Performance
https://www.readbyqxmd.com/read/28457229/correlation-between-therapy-and-lipid-profile-of-leprosy-patients-is-there-a-higher-risk-for-developing-cardiovascular-diseases-after-treatment
#17
Rosalba V G Silva, Rafael S de Araújo, Tinara L S Aarão, Paulo Diovanne da Silva Costa, Jorge R Sousa, Juarez A S Quaresma
BACKGROUND: The impact of leprosy reduces health-related quality of life of affected patients, interfering with different factors such as nutrition. This study investigated the lipid profile, nutritional status, and risk for cardiovascular disease (CVD) in patients who underwent leprosy treatment in Brazil. METHODS: Eighty-four adult patients of both genders ranging in age from 20 to 60 years and diagnosed with paucibacillary (PB) or multibacillary (MB) leprosy were selected after undergoing multidrug treatment...
May 1, 2017: Infectious Diseases of Poverty
https://www.readbyqxmd.com/read/28456538/plasma-fatty-acid-patterns-during-pregnancy-and-child-s-growth-body-composition-and-cardiometabolic-health-the-generation-r-study
#18
Trudy Voortman, Myrte J Tielemans, Wendy Stroobant, Josje D Schoufour, Jessica C Kiefte-de Jong, Jolien Steenweg-de Graaff, Edith H van den Hooven, Henning Tiemeier, Vincent W V Jaddoe, Oscar H Franco
BACKGROUND: Exposure to different concentrations of fatty acids during fetal life may affect growth and metabolism. However, most studies examined individual fatty acids, whereas concentrations highly correlate and may interact with each other. We aimed to evaluate patterns of plasma fatty acids during pregnancy and their associations with growth, body composition, and cardiometabolic health of the 6-year-old offspring. METHODS: This study was performed in 4830 mother-child pairs participating in a population-based cohort in the Netherlands...
April 13, 2017: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/28451083/prevalence-of-cardio-metabolic-risk-factors-in-a-nationally-representative-sample-of-iranian-adolescents-the-caspian-iii-study
#19
Roya Kelishadi, Ramin Heshmat, Farshad Farzadfar, Mohammad Esmaeil Motlag, Maryam Bahreynian, Saeid Safiri, Gelayol Ardalan, Ehsan Rezaei Darzi, Hamid Asayesh, Fatemeh Rezaei, Mostafa Qorbani
Introduction: The aim of the present study is to explore the prevalence and mean of cardiometabolic risk factors and liver enzymes of Iranian adolescents living in regions with different socioeconomic status (SES). To the best of our knowledge this is the first study reporting these data at sub-national level in Iran. Methods: This multi-centric study was performed in 2009-2010 on a stratified multi-stage probability sample of 5940 students aged 10-18 years, living in urban and rural areas of 27 provinces of Iran...
2017: Journal of Cardiovascular and Thoracic Research
https://www.readbyqxmd.com/read/28445437/an-exploratory-study-on-the-influence-of-psychopathological-risk-and-impulsivity-on-bmi-and-perceived-quality-of-life-in-obese-patients
#20
Renata Tambelli, Luca Cerniglia, Silvia Cimino, Giulia Ballarotto, Marinella Paciello, Carla Lubrano, Serena Marchitelli, Lucio Gnessi, Andrea Lenzi
The present study aimed to assess the psychological profiles of adult male and female obese patients, as well as to verify the possible influence of their psychopathological risk and impulsivity on their body mass index (BMI) and perceived quality of life. A total of 64 obese subjects accessing a center for care of their obesity were assessed through anthropometric and psychometric measurements. All anthropometric measures in men were higher than in women, while in turn, women showed higher psychopathological symptoms...
April 26, 2017: Nutrients
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