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https://www.readbyqxmd.com/read/29118991/factors-increasing-the-risk-for-psychosocial-stress-among-korean-adults-living-in-rural-areas-using-generalized-estimating-equations-and-mixed-models
#1
Ju-Hyun Nam, Myeong-Seob Lim, Hyun-Kyeong Choi, Jae-Yeop Kim, Sung-Kyeong Kim, Sung-Soo Oh, Sang-Baek Koh, Hee-Tae Kang
Background: This study was conducted to analyze the distribution of the psychosocial well-being index among adults living in two rural communities in Korea and to examine its correlation with lifestyle variables such as sleep duration, regular exercise, and sedentary time. Methods: Using the cohort data of the Atherosclerosis Risk of a Rural Area Korean General Population, this study examined 3631 participants living in Wonju and Pyeongchang in Gangwon Province; their preliminary data were established from 2005 to 2007 while their follow-up data were collected 3 years later...
2017: Annals of Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/29104150/differentiating-between-primary-central-nervous-system-lymphomas-and-glioblastomas-combined-use-of-perfusion-and-diffusion-weighted-magnetic-resonance-imaging
#2
Keishi Makino, Toshinori Hirai, Hideo Nakamura, Jun-Ichiro Kuroda, Naoki Shinojima, Hiroyuki Uetani, Mika Kitajima, Shigetoshi Yano
OBJECTIVE: The purpose of this study was to determine whether combined diffusion-weighted imaging (DWI) and dynamic susceptibility contrast-enhanced perfusion-weighted imaging (PWI) magnetic resonance imaging (MRI) can be used to differentiate between common malignant brain tumors, including lymphomas and high-grade gliomas. METHODS: We evaluated 87 patients with histologically confirmed brain tumors, including 33 primary central nervous system lymphomas (PCNSLs) and 54 glioblastomas (GBMs)...
November 2, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/29081762/a-comparison-of-relative-time-to-peak-and-tmax-for-mismatch-based-patient-selection
#3
Anke Wouters, Søren Christensen, Matus Straka, Michael Mlynash, John Liggins, Roland Bammer, Vincent Thijs, Robin Lemmens, Gregory W Albers, Maarten G Lansberg
BACKGROUND AND PURPOSE: The perfusion-weighted imaging (PWI)/diffusion-weighted imaging (DWI) mismatch profile is used to select patients for endovascular treatment. A PWI map of Tmax is commonly used to identify tissue with critical hypoperfusion. A time to peak (TTP) map reflects similar hemodynamic properties with the added benefit that it does not require arterial input function (AIF) selection and deconvolution. We aimed to determine if TTP could substitute Tmax for mismatch categorization...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/29074634/do-fluid-attenuated-inversion-recovery-vascular-hyperintensities-represent-good-collaterals-before-reperfusion-therapy
#4
E Mahdjoub, G Turc, L Legrand, J Benzakoun, M Edjlali, P Seners, S Charron, W Ben Hassen, O Naggara, J-F Meder, J-L Mas, J-C Baron, C Oppenheim
BACKGROUND AND PURPOSE: In acute ischemic stroke, whether FLAIR vascular hyperintensities represent good or poor collaterals remains controversial. We hypothesized that extensive FLAIR vascular hyperintensities correspond to good collaterals, as indirectly assessed by the hypoperfusion intensity ratio. MATERIALS AND METHODS: We included 244 consecutive patients eligible for reperfusion therapy with MCA stroke and pretreatment MR imaging with both FLAIR and PWI. The FLAIR vascular hyperintensity score was based on ASPECTS, ranging from 0 (no FLAIR vascular hyperintensity) to 7 (FLAIR vascular hyperintensities abutting all ASPECTS cortical areas)...
October 26, 2017: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/29060532/mri-based-objective-ischemic-core-penumbra-quantification-in-adult-clinical-stroke
#5
Anusha Vupputuri, Stephen Ashwal, Bryan Tsao, Elia Haddad, Nirmalya Ghosh
Objective and non-invasive quantification of ischemic stroke and differentiation of salvageable from non-salvageable tissue is critical to treatment planning. However current Magnetic Resonance Imaging(MRI) techniques are time consuming and rely on manual detection methods. Computer aided preliminary screening of the injured tissue could assist neuroradiologists in performing more detailed analysis of the lesion components. An established Hierarchical Region Splitting (HRS) method was extended to segment lesions from adult patients who suffered a clinical stroke using diffusion- and perfusion weighted image (DWI-PWI) maps and associated computed maps...
July 2017: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/29024074/comparison-of-subjective-wellbeing-in-substance-users-and-the-parents-or-partners-of-substance-users
#6
Robert J Tait
INTRODUCTION AND AIMS: There is growing interest in the impact of substance use on both the individual consumer's subjective wellbeing (SWB) and the reduced SWB of those closely connected to him or her. The study aimed to compare SWB among substance users ('consumers') and the parents or partners affected by another's substance use, and to evaluate the effect of counselling on changed SWB to 6 months. DESIGN AND METHODS: The study used longitudinal data from a not-for-profit treatment service based in Perth, Australia...
October 12, 2017: Drug and Alcohol Review
https://www.readbyqxmd.com/read/29019892/bright-sinus-appearance-on-arterial-spin-labeling-mr-imaging-aids-to-identify-cerebral-venous-thrombosis
#7
Ji Hee Kang, Tae Jin Yun, Roh-Eul Yoo, Byung-Woo Yoon, A Leum Lee, Koung Mi Kang, Seung Hong Choi, Ji-Hoon Kim, Chul-Ho Sohn, Moon Hee Han
Cerebral venous thrombosis is a potentially lethal disease. Early diagnosis is essential to improve its prognosis. However, its early diagnosis based on conventional imaging modalities remains a challenge in clinical settings. The purpose of this study was to evaluate whether bright sinus appearance on arterial spin-labeling perfusion-weighted image (ASL-PWI) could help identify cerebral venous thrombosis.ASL-PWI of 13 patients who were confirmed as cerebral venous thrombosis based on neurologic symptoms and computed tomography (CT) or magnetic resonance (MR) venography (with/without cerebral angiography) were retrospectively analyzed for the presence or absence of the following: bright signal in dural sinus termed "bright sinus appearance"; and hypoperfusion in brain parenchyma drained by thrombosed sinus...
October 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28962101/perfusion-weighted-magnetic-resonance-imaging-in-the-assessment-of-haemodynamics-following-stent-angioplasty-in-patients-with-symptomatic-middle-cerebral-artery-plaque-stenosis-at-the-m1-segment
#8
Yun-Cai Ran, Ming Zhu, Yong Zhang, Teng-Fei Li, Jing-Liang Cheng
The most effective strategy to assess changes in the brain haemodynamics of stent angioplasty in patients with symptomatic ischemia of the M1 segment of the middle cerebral artery (MCA) remains unknown. The purpose of the present study was to use perfusion-weighted magnetic resonance imaging (PWI) to evaluate the effect of stent angioplasty in treating patients with symptomatic MCA plaque stenosis. Stent angioplasty was performed on 23 patients with reduplicative transient ischaemic attack who were refractory to medical therapy...
September 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/28961111/inverse-problem-of-ultrasound-beamforming-with-sparsity-constraints-and-regularization
#9
Ece Ozkan, Valeriy Vishnevsky, Orcun Goksel
Ultrasound (US) beamforming is the process of reconstructing an image from acquired echo traces on several transducer elements. Typical beamforming approaches, such as Delay-And-Sum, perform simple projection operations, while techniques using statistical information also exist, e.g. adaptive, phase-coherence, Delay-Multiply-And-Sum, and sparse coding approaches. Inspired by the feasibility and success of inverse problem formulations in several image reconstruction problems, such as computed tomography, we herein devise an inverse problem approach for US beamforming...
September 28, 2017: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
https://www.readbyqxmd.com/read/28952228/differentiation-between-progression-and-pseudoprogresion-by-arterial-spin-labeling-mri-in-patients-with-glioblastoma-multiforme
#10
Marija Jovanovic, Sandra Radenkovic, Tatjana Stosic-Opincal, Slobodan Lavrnic, Svetlana Gavrilovic, Biljana Lazovic-Popovic, Ivan Soldatovic, Ruzica Maksimovic
PURPOSE: To compare arterial spin labeling (ASL) perfusion technique with the clinically established dynamic susceptibility contrast-enhanced (DSC) perfusion weighted-imaging (PWI), and to determine its value in routine MRI evaluation of disease progression in patients with glioblastoma multiforme (GBM). METHODS: A prospective intraindividual study was performed in 31 patients with histologically proven GBM who had clinical and/or radiological deterioration after treatment, including surgery, radiotherapy and therapy with temozolomide...
July 2017: Journal of B.U.ON.: Official Journal of the Balkan Union of Oncology
https://www.readbyqxmd.com/read/28929836/the-relationship-between-blood-flow-impairment-and-oxygen-depletion-in-acute-ischemic-stroke-imaged-with-magnetic-resonance-imaging
#11
Alexander Seiler, Nicholas P Blockley, Ralf Deichmann, Ulrike Nöth, Oliver C Singer, Michael A Chappell, Johannes C Klein, Marlies Wagner
Oxygenation-sensitive spin relaxation time T2' and relaxation rate R2' (1/T2') are presumed to be markers of the cerebral oxygen extraction fraction (OEF) in acute ischemic stroke. In this study, we investigate the relationship of T2'/R2' with dynamic susceptibility contrast-based relative cerebral blood flow (rCBF) in acute ischemic stroke to assess their plausibility as surrogate markers of the ischemic penumbra. Twenty-one consecutive patients with internal carotid artery and/or middle cerebral artery occlusion were studied at 3...
January 1, 2017: Journal of Cerebral Blood Flow and Metabolism
https://www.readbyqxmd.com/read/28892580/correlation-of-quantitative-parameters-of-magnetic-resonance-perfusion-weighted-imaging-with-vascular-endothelial-growth-factor-microvessel-density-and-hypoxia-inducible-factor-1%C3%AE-in-nasopharyngeal-carcinoma-evaluation-on-radiosensitivity-study
#12
Y Hu, H E, X Yu, F Li, L Zeng, Q Lu, X Xi, L Shen
OBJECTIVES: To investigate the correlation of parameters of magnetic resonance perfusion-weighted imaging (MR-PWI) with the expression of vascular endothelial growth factor (VEGF), hypoxia-inducible factor-1α (HIF-1α) and microvessel density (MVD) in nasopharyngeal carcinoma (NPC) so as to explore the value of predicting radiosensitivity. DESIGN: A prospective study. SETTING: Department of Head-and-neck radiotherapy in Hunan Cancer Hospital...
September 11, 2017: Clinical Otolaryngology
https://www.readbyqxmd.com/read/28862482/pseudoprogression-after-glioma-therapy-an-update
#13
Norbert Galldiks, Martin Kocher, Karl-Josef Langen
Initial diagnostics and follow-up of gliomas is usually based on contrast-enhanced MRI. However, the capacity of standard MRI to differentiate neoplastic tissue from posttherapeutic effects such as pseudoprogression is limited. Advanced neuroimaging methods may provide relevant additional information, which allow for a more accurate diagnosis especially in clinically equivocal situations. This review article focuses predominantly on PET using radiolabeled amino acids and advanced MRI techniques such as perfusion-weighted imaging (PWI) and summarizes the efforts of these methods regarding the identification of pseudoprogression after glioma therapy...
September 7, 2017: Expert Review of Neurotherapeutics
https://www.readbyqxmd.com/read/28860608/fmiso-pet-derived-brain-oxygen-tension-maps-application-to-glioblastoma-and-less-aggressive-gliomas
#14
Ararat Chakhoyan, Jean-Sebastien Guillamo, Solène Collet, François Kauffmann, Nicolas Delcroix, Emmanuèle Lechapt-Zalcman, Jean-Marc Constans, Edwige Petit, Eric T MacKenzie, Louisa Barré, Myriam Bernaudin, Omar Touzani, Samuel Valable
Quantitative imaging modalities for the analysis of hypoxia in brain tumors are lacking. The objective of this study was to generate absolute maps of tissue ptO2 from [(18)F]-FMISO images in glioblastoma and less aggressive glioma patients in order to quantitatively assess tumor hypoxia. An ancillary objective was to compare estimated ptO2 values to other biomarkers: perfusion weighted imaging (PWI) and tumor metabolism obtained from (1)H-MR mono-voxel spectroscopy (MRS). Ten patients with glioblastoma (GBM) and three patients with less aggressive glioma (nGBM) were enrolled...
August 31, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28851301/clinical-features-and-the-degree-of-cerebrovascular-stenosis-in-different-types-and-subtypes-of-cerebral-watershed-infarction
#15
Yue Li, Man Li, Xiaoyu Zhang, Shuna Yang, Huimin Fan, Wei Qin, Lei Yang, Junliang Yuan, Wenli Hu
BACKGROUND: Whether there are differences in pathogenesis among different types and subtypes of cerebral watershed infarction (WSI) is controversial since they have been combined into a single group in most previous studies. METHODS: We prospectively identified 340 supratentorial WSI patients at Beijing Chao-Yang Hospital, Capital Medical University, China and classified them based on diffusion-weighted imaging(DWI) templates. Baseline characteristics, clinical courses and neuroradiological features were compared among patients with different types and subtypes of WSI...
August 29, 2017: BMC Neurology
https://www.readbyqxmd.com/read/28831534/comparison-of-18-f-fet-pet-and-perfusion-weighted-mri-for-glioma-grading-a-hybrid-pet-mr-study
#16
Antoine Verger, Christian P Filss, Philipp Lohmann, Gabriele Stoffels, Michael Sabel, Hans J Wittsack, Elena Rota Kops, Norbert Galldiks, Gereon R Fink, Nadim J Shah, Karl-Josef Langen
PURPOSE: Both perfusion-weighted MR imaging (PWI) and O-(2-(18)F-fluoroethyl)-L-tyrosine PET ((18)F-FET) provide grading information in cerebral gliomas. The aim of this study was to compare the diagnostic value of (18)F-FET PET and PWI for tumor grading in a series of patients with newly diagnosed, untreated gliomas using an integrated PET/MR scanner. METHODS: Seventy-two patients with untreated gliomas [22 low-grade gliomas (LGG), and 50 high-grade gliomas (HGG)] were investigated with (18)F-FET PET and PWI using a hybrid PET/MR scanner...
December 2017: European Journal of Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/28829836/reference-intervals-of-echocardiographic-measurements-in-healthy-adult-dairy-goats
#17
Olga Szaluś-Jordanow, Michał Czopowicz, Lucjan Witkowski, Marcin Mickiewicz, Tadeusz Frymus, Iwona Markowska-Daniel, Emilia Bagnicka, Jarosław Kaba
OBJECTIVES: To determine references intervals for echocardiographic measurements in adult dairy goats. ANIMALS: 125 clinically healthy, adult dairy goats aged 2-9 years, belonging to two breeds-Polish Fawn Improved (PFI, n = 64, weight range from 46 to 73, median of 58.5kg) and Polish White Improved (PWI, n = 61, weight range from 48 to 80 kg, median of 67.9kg), closely related to French Alpine and Saanen, respectively. METHODS: Non-invasive transthoracic echocardiography examination was performed in unsedated goats in a standing position...
2017: PloS One
https://www.readbyqxmd.com/read/28796443/relative-cerebral-blood-volume-is-a-potential-biomarker-in-late-delayed-radiation-induced-brain-injury
#18
Ying Xie, Haiwei Huang, Junjie Guo, Dongxiao Zhou
PURPOSE: To assess whether relative cerebral blood volume (rCBV) can provide information to reliably evaluate the stages of late delayed radiation-induced brain injury. MATERIALS AND METHODS: Forty patients diagnosed with late delayed radiation-induced brain injury were enrolled. The patients were examined using a 1.5T magnetic resonance imaging (MRI) system equipped with an 8-channel head coil. An echo planar imaging (EPI) sequence was used in perfusion-weighted imaging (PWI)...
August 10, 2017: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/28792891/feasibility-and-validation-of-4-d-pulse-wave-imaging-in-phantoms-and-in-vivo
#19
Iason-Zacharias Apostolakis, Pierre Nauleau, Clement Papadacci, Matthew D McGarry, Elisa E Konofagou
Pulse wave imaging (PWI) is a noninvasive technique for tracking the propagation of the pulse wave along the arterial wall. The 3-D ultrasound imaging would aid in objectively estimating the pulse wave velocity (PWV) vector. This paper aims to introduce a novel PWV estimation method along the propagation direction, validate it in phantoms, and test its feasibility in vivo. A silicone vessel phantom consisting of a stiff and a soft segment along the longitudinal axis and a silicone vessel with a plaque were constructed...
September 2017: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
https://www.readbyqxmd.com/read/28780227/insights-into-the-immune-manipulation-mechanisms-of-pollen-allergens-by-protein-domain-profiling
#20
Seema Patel, Aruna Rani, Arun Goyal
Plant pollens are airborne allergens, as their inhalation causes immune activation, leading to rhinitis, conjunctivitis, sinusitis and oral allergy syndrome. A myriad of pollen proteins belonging to profilin, expansin, polygalacturonase, glucan endoglucosidase, pectin esterase, and lipid transfer protein class have been identified. In the present in silico study, the protein domains of fifteen pollen sequences were extracted from the UniProt database and submitted to the interactive web tool SMART (Simple Modular Architecture Research Tool), for finding the protein domain profiles...
July 29, 2017: Computational Biology and Chemistry
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