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Hierarchical Condition Category

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https://www.readbyqxmd.com/read/27875178/optimizing-hierarchical-visualizations-with-the-minimum-description-length-principle
#1
Rafael Veras, Christopher Collins
In this paper we examine how the Minimum Description Length (MDL) principle can be used to efficiently select aggregated views of hierarchical datasets that feature a good balance between clutter and information. We present MDL formulae for generating uneven tree cuts tailored to treemap and sunburst diagrams, taking into account the available display space and information content of the data. We present the results of a proof-of-concept implementation. In addition, we demonstrate how such tree cuts can be used to enhance drill-down interaction in hierarchical visualizations by implementing our approach in an existing visualization tool...
January 2017: IEEE Transactions on Visualization and Computer Graphics
https://www.readbyqxmd.com/read/27816950/performance-evaluation-of-immunocap%C3%A2-isac-112-a-multi-site-study
#2
Marianne van Hage, Peter Schmid-Grendelmeier, Chrysanthi Skevaki, Mario Plebani, Walter Canonica, Jörg Kleine-Tebbe, Mats Nystrand, Mehrdad Jafari-Mamaghani, Thilo Jakob
BACKGROUND: After the re-introduction of ImmunoCAP® ISAC sIgE 112 on the market, we undertook a study to evaluate the performance of this multiplex-based immunoassay for IgE measurements to allergen components. METHODS: The study was carried out at 22 European and one South African site. Microarrays from different batches, eight specific IgE (sIgE) positive, three sIgE negative serum samples and a calibration sample were sent to participating laboratories where assays were performed according to the manufacturer's instructions...
November 7, 2016: Clinical Chemistry and Laboratory Medicine: CCLM
https://www.readbyqxmd.com/read/27736239/future-directions-for-clinical-research-services-and-training-evidence-based-assessment-across-informants-cultures-and-dimensional-hierarchies
#3
Thomas M Achenbach
As the Diagnostic and Statistical Manual of Mental Disorders (5th ed.; DSM-5) acknowledges, DSM diagnostic categories do not fit the real-world heterogeneity, comorbidity, and complexity of most mental health problems. Many efforts to develop and test evidence-based treatments also fail to take account of the heterogeneity, comorbidity, and complexity of problems seen in the community settings where most mental health services are rendered. Most community services cannot attain the treatment specificity and fidelity characterizing randomized controlled trials, which often yield larger therapeutic effects than when the tested treatments are tried in community services...
October 13, 2016: Journal of Clinical Child and Adolescent Psychology
https://www.readbyqxmd.com/read/27711249/-on-my-own-but-not-alone-adolescents-experiences-of-internet-delivered-cognitive-behavior-therapy-for-obsessive-compulsive-disorder
#4
Fabian Lenhard, Sarah Vigerland, Hedvig Engberg, Anna Hallberg, Hanna Thermaenius, Eva Serlachius
INTRODUCTION: Childhood Obsessive-Compulsive Disorder (OCD) is a prevalent and impairing condition that can be effectively treated with Cognitive Behavior Therapy (CBT). However, a majority of children and adolescents do not have access to CBT. Internet-delivered CBT (ICBT) has been suggested as a way to increase availability to effective psychological treatments. Yet, the research on ICBT in children and adolescents has been lagging behind significantly both when it comes to quantitative as well as qualitative studies...
2016: PloS One
https://www.readbyqxmd.com/read/27682525/implications-of-the-definition-of-an-episode-of-care-used-in-the-comprehensive-care-for-joint-replacement-model
#5
Chad Ellimoottil, Andrew M Ryan, Hechuan Hou, James M Dupree, Brian Hallstrom, David C Miller
Importance: Under the Comprehensive Care for Joint Replacement (CJR) model, hospitals are held accountable for nearly all Medicare payments that occur during the initial hospitalization until 90 days after hospital discharge (ie, the episode of care). It is not known whether unrelated expenditures resulting from this "broad" definition of an episode of care will affect participating hospitals' average episode-of-care payments. Objective: To compare the CJR program's broad definition of an episode of care with a clinically narrow definition of an episode of care...
September 28, 2016: JAMA Surgery
https://www.readbyqxmd.com/read/27592179/differences-in-nursing-home-quality-between-medicare-advantage-and-traditional-medicare-patients
#6
Emiley Chang, Teague Ruder, Claude Setodji, Debra Saliba, Mark Hanson, David S Zingmond, Neil S Wenger, David A Ganz
BACKGROUND: Medicare Advantage (MA) enrollment is steadily growing, but little is known about the quality of nursing home (NH) care provided to MA enrollees compared to enrollees in traditional fee-for-service (FFS) Medicare. OBJECTIVES: To compare MA and FFS enrollees' quality of NH care. DESIGN: Cross-sectional. SETTING: US nursing homes. PARTICIPANTS: 2.17 million Medicare enrollees receiving care at an NH during 2011...
October 1, 2016: Journal of the American Medical Directors Association
https://www.readbyqxmd.com/read/27492451/comorbidity-indices-versus-function-as-potential-predictors-of-30-day-readmission-in-older-patients-following-postacute-rehabilitation
#7
Amit Kumar, Amol M Karmarkar, James E Graham, Linda Resnik, Alai Tan, Anne Deutsch, Kenneth J Ottenbacher
BACKGROUND: Information regarding the association of comorbidity indices with readmission risk for older adults receiving postacute care is limited. The purpose of this study was to compare the discriminatory ability of five comorbidity indices in predicting 30-day all-cause hospital readmission following discharge to the community from postacute inpatient rehabilitation facilities (IRF). METHODS: The sample included Medicare fee-for-service beneficiaries with stroke, lower extremity joint replacement, and fracture, discharged from IRF in 2011 (N = 75,582)...
August 4, 2016: Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
https://www.readbyqxmd.com/read/27431801/depression-treatment-decreases-healthcare-expenditures-among-working-age-patients-with-comorbid-conditions-and-type-2-diabetes-mellitus-along-with-newly-diagnosed-depression
#8
Rituparna Bhattacharya, Chan Shen, Amy B Wachholtz, Nilanjana Dwibedi, Usha Sambamoorthi
BACKGROUND: There are many studies in the literature on the association between depression treatment and health expenditures. However, there is a knowledge gap in examining this relationship taking into account coexisting chronic conditions among patients with diabetes. We aim to analyze the association between depression treatment and healthcare expenditures among adults with Type 2 Diabetes Mellitus (T2DM) and newly-diagnosed depression, with consideration of coexisting chronic physical conditions...
July 19, 2016: BMC Psychiatry
https://www.readbyqxmd.com/read/27322485/association-between-medicare-accountable-care-organization-implementation-and-spending-among-clinically-vulnerable-beneficiaries
#9
Carrie H Colla, Valerie A Lewis, Lee-Sien Kao, A James O'Malley, Chiang-Hua Chang, Elliott S Fisher
IMPORTANCE: Accountable care contracts hold physician groups financially responsible for the quality and cost of health care delivered to patients. Focusing on clinically vulnerable patients, those with serious conditions who are responsible for the greatest proportion of spending, may result in the largest effects on both patient outcomes and financial rewards for participating physician groups. OBJECTIVE: To estimate the effect of Medicare accountable care organization (ACO) contracts on spending and high-cost institutional use for all Medicare beneficiaries and for clinically vulnerable beneficiaries...
August 1, 2016: JAMA Internal Medicine
https://www.readbyqxmd.com/read/27155471/synergic-stress-in-striped-catfish-pangasianodon-hypophthalmus-s-exposed-to-chronic-salinity-and-bacterial-infection-effects-on-kidney-protein-expression-profile
#10
REVIEW
Mélodie Schmitz, Syaghalirwa N M Mandiki, Jessica Douxfils, Tamar Ziv, Arie Admon, Patrick Kestemont
UNLABELLED: Hyperosmotic stress has often been investigated from osmoregulation perspectives while the effects of such stress on the immune capacity remain largely unexplored. In this study, striped catfish were submitted to a gradual hyperosmotic stress (up to 20ppt), followed by an infection with a virulent strain of an intracellular bacteria, Edwardsiella ictaluri. Physiological parameters (plasma osmolarity, gill NaK ATPase) have been investigated. Moreover, a label free quantitative proteomics workflow was used to study how salinity affects the proteome of kidney of no infected and infected fish...
June 16, 2016: Journal of Proteomics
https://www.readbyqxmd.com/read/27149597/comparing-comorbidity-indices-to-predict-post-acute-rehabilitation-outcomes-in-older-adults
#11
Amit Kumar, James E Graham, Linda Resnik, Amol M Karmarkar, Alai Tan, Anne Deutsch, Kenneth J Ottenbacher
OBJECTIVE: Compare 5 comorbidity indices to predict community discharge and functional status following post-acute rehabilitation. DESIGN: This was a retrospective study of Medicare beneficiaries with stroke, lower-extremity fracture, and joint replacement discharged from inpatient rehabilitation in 2011 (N = 105,275). Community discharge and self-care, mobility, and cognitive function were compared using the Charlson, Elixhauser, Tier, Functional Comorbidity, and Hierarchical Condition Category comorbidity indices...
December 2016: American Journal of Physical Medicine & Rehabilitation
https://www.readbyqxmd.com/read/27085370/county-level-variation-in-emergency-department-admission-rates-among-us-medicare-beneficiaries
#12
Kadin Caines, Carla Shoff, David M Bott, Jesse M Pines
STUDY OBJECTIVE: Hospital-based emergency departments (EDs) are the gateway to hospital admissions for many Americans. Approximately half of all US hospital admissions originate from EDs, and more than 3 in 4 are among Medicare beneficiaries. Recent literature has demonstrated nearly 2-fold variation in both physician- and hospital-level ED admission rates. We study geographic variation at the county level in ED admission rates among Medicare fee-for-service beneficiaries. METHODS: Using the 100% population data from the Centers for Medicare & Medicaid Services (CMS), we analyzed beneficiaries continuously enrolled in Medicare fee-for-service Parts A and B who resided in the 50 states and the District of Columbia in 2012...
October 2016: Annals of Emergency Medicine
https://www.readbyqxmd.com/read/27015176/adolescent-bmi-at-northern-israel-from-trends-to-associated-variables-and-comorbidities-and-to-medical-signatures
#13
Yossy Machluf, Daniel Fink, Rivka Farkash, Ron Rotkopf, Avinoam Pirogovsky, Orna Tal, Tamar Shohat, Giora Weisz, Erez Ringler, David Dagan, Yoram Chaiter
The increasing prevalence of abnormal body mass index (BMI), mainly obesity, is becoming a significant public health problem. This cross-sectional study aimed to provide a comprehensive view of secular trends of BMI, and the associated socio-demographic variables and comorbidities among adolescents with abnormal BMI. Individuals of the study population were born mainly between 1970 and 1993, and were examined at 16 to 19 years of age during the years 1987 to 2010, at 1 conscription center in the northern district of Israel...
March 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/26939870/the-denominator-problem-national-hospital-quality-measures-for-acute-myocardial-infarction
#14
Jeffrey Bruckel, Xiu Liu, Samuel F Hohmann, Andrew S Karson, Elizabeth Mort, David M Shahian
BACKGROUND: National Hospital Quality Measures (NHQM) should accurately reflect quality of care, as they increasingly impact reimbursement and reputation. However, similar to risk adjustment of outcomes measures, NHQM process measures pose unique methodological concerns, including lack of representativeness of the final denominator population after exclusions. This study determines population size and characteristics for each acute myocardial infarction (AMI) measure, reasons for exclusion from the measures, and variation in exclusion rates among hospitals...
March 3, 2016: BMJ Quality & Safety
https://www.readbyqxmd.com/read/26931813/delta-theta-beta-and-gamma-brain-oscillations-index-levels-of-auditory-sentence-processing
#15
Guangting Mai, James W Minett, William S-Y Wang
A growing number of studies indicate that multiple ranges of brain oscillations, especially the delta (δ, <4Hz), theta (θ, 4-8Hz), beta (β, 13-30Hz), and gamma (γ, 30-50Hz) bands, are engaged in speech and language processing. It is not clear, however, how these oscillations relate to functional processing at different linguistic hierarchical levels. Using scalp electroencephalography (EEG), the current study tested the hypothesis that phonological and the higher-level linguistic (semantic/syntactic) organizations during auditory sentence processing are indexed by distinct EEG signatures derived from the δ, θ, β, and γ oscillations...
June 2016: NeuroImage
https://www.readbyqxmd.com/read/26918404/risk-standardized-acute-admission-rates-among-patients-with-diabetes-and-heart-failure-as-a-measure-of-quality-of-accountable-care-organizations-rationale-methods-and-early-results
#16
Erica S Spatz, Kasia J Lipska, Ying Dai, Haikun Bao, Zhenqiu Lin, Craig S Parzynski, Faseeha K Altaf, Erin K Joyce, Julia A Montague, Joseph S Ross, Susannah M Bernheim, Harlan M Krumholz, Elizabeth E Drye
BACKGROUND: Population-based measures of admissions among patients with chronic conditions are important quality indicators of Accountable Care Organizations (ACOs), yet there are challenges in developing measures that enable fair comparisons among providers. METHODS: On the basis of consensus standards for outcome measure development and with expert and stakeholder input on methods decisions, we developed and tested 2 models of risk-standardized acute admission rates (RSAARs) for patients with diabetes and heart failure using 2010-2012 Medicare claims data...
May 2016: Medical Care
https://www.readbyqxmd.com/read/26891974/a-machine-learning-framework-for-plan-payment-risk-adjustment
#17
Sherri Rose
OBJECTIVE: To introduce cross-validation and a nonparametric machine learning framework for plan payment risk adjustment and then assess whether they have the potential to improve risk adjustment. DATA SOURCES: 2011-2012 Truven MarketScan database. STUDY DESIGN: We compare the performance of multiple statistical approaches within a broad machine learning framework for estimation of risk adjustment formulas. Total annual expenditure was predicted using age, sex, geography, inpatient diagnoses, and hierarchical condition category variables...
February 19, 2016: Health Services Research
https://www.readbyqxmd.com/read/26595225/comparison-of-comorbidity-scores-in-predicting-surgical-outcomes
#18
Hemalkumar B Mehta, Francesca Dimou, Deepak Adhikari, Nina P Tamirisa, Eric Sieloff, Taylor P Williams, Yong-Fang Kuo, Taylor S Riall
INTRODUCTION: The optimal methodology for assessing comorbidity to predict various surgical outcomes such as mortality, readmissions, complications, and failure to rescue (FTR) using claims data has not been established. OBJECTIVE: Compare diagnosis-based and prescription-based comorbidity scores for predicting surgical outcomes. METHODS: We used 100% Texas Medicare data (2006-2011) and included patients undergoing coronary artery bypass grafting, pulmonary lobectomy, endovascular repair of abdominal aortic aneurysm, open repair of abdominal aortic aneurysm, colectomy, and hip replacement (N=39,616)...
February 2016: Medical Care
https://www.readbyqxmd.com/read/26569129/a-dynamic-model-of-reasoning-and-memory
#19
Guy E Hawkins, Brett K Hayes, Evan Heit
Previous models of category-based induction have neglected how the process of induction unfolds over time. We conceive of induction as a dynamic process and provide the first fine-grained examination of the distribution of response times observed in inductive reasoning. We used these data to develop and empirically test the first major quantitative modeling scheme that simultaneously accounts for inductive decisions and their time course. The model assumes that knowledge of similarity relations among novel test probes and items stored in memory drive an accumulation-to-bound sequential sampling process: Test probes with high similarity to studied exemplars are more likely to trigger a generalization response, and more rapidly, than items with low exemplar similarity...
February 2016: Journal of Experimental Psychology. General
https://www.readbyqxmd.com/read/26564253/examining-the-association-between-comorbidity-indexes-and-functional-status-in-hospitalized-medicare-fee-for-service-beneficiaries
#20
Amit Kumar, James E Graham, Linda Resnik, Amol M Karmarkar, Anne Deutsch, Alai Tan, Soham Al Snih, Kenneth J Ottenbacher
BACKGROUND: Medicare data from acute hospitals do not contain information on functional status. This lack of information limits the ability to conduct rehabilitation-related health services research. OBJECTIVE: The purpose of this study was to examine the associations between 5 comorbidity indexes derived from acute care claims data and functional status assessed at admission to an inpatient rehabilitation facility (IRF). Comorbidity indexes included tier comorbidity, Functional Comorbidity Index (FCI), Charlson Comorbidity Index, Elixhauser Comorbidity Index, and Hierarchical Condition Category (HCC)...
February 2016: Physical Therapy
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