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Rodrigo Dalke Meucci, Angélica Ozório Linhares, Daniel Wenceslau Votto Olmedo, Ewerton Luiz Porto Cousin Sobrinho, Vlanice Madruga Duarte, Juraci Almeida Cesar
The scope of this article is to assess low back pain prevalence and associated factors in the last 12 months among adolescents in a city in the south of the State of Piauí. It was a cross-sectional study which included 1,112 adolescents aged 13-19 in the city of Caracol, Piauí. Demographic, socio-economic, nutritional, behavioral and comorbidty characteristics were investigated. The outcome was the occurrence of low back pain (LBP) in the last 12 months. The outcome prevalence was calculated in accordance with independent variables...
March 2018: Ciência & Saúde Coletiva
Evan L Brittain, Meredith S Duncan, Joyce Chang, Olga V Patterson, Scott L DuVall, Cynthia A Brandt, Kaku A So-Armah, Matthew Goetz, Kathleen Akgun, Kristina Crothers, Courtney Zola, Joon Kim, Cynthia Gibert, Margaret Pisani, Alison Morris, Priscilla Hsue, Hilary A Tindle, Amy Justice, Matthew Freiberg
RATIONALE: The epidemiology and prognostic impact of increased pulmonary pressure among HIV-infected individuals in the antiretroviral therapy era is not well described. OBJECTIVES: To examine the prevalence, clinical features, and outcomes of increased echocardiographic pulmonary pressure in HIV-infected and -uninfected individuals. METHODS: This study evaluated 8,296 veterans referred for echocardiography with reported pulmonary artery systolic pressure (PASP) estimates from the Veterans Aging Cohort study, an observational cohort of HIV-infected and -uninfected veterans matched by age, sex, race/ethnicity, and clinical site...
April 1, 2018: American Journal of Respiratory and Critical Care Medicine
Stine Braendegaard Winther, Pia Österlund, Åke Berglund, Bengt Glimelius, Camilla Qvortrup, Halfdan Sorbye, Per Pfeiffer
BACKGROUND: Metastatic colorectal cancer (mCRC) is a disease of older age, but there is a relative lack of knowledge about effects of chemotherapy in older patients as they are under-represented in clinical trials. Little data can guide whether the strategy in older mCRC patients should be a sequential full-dose monotherapy chemotherapy approach or a dose-reduced combination chemotherapy approach. The oral 5FU prodrug S-1 seems to have less side effects than capecitabine and should be an optimal drug for older patients, but few data are available...
August 16, 2017: BMC Cancer
Yonas Getaye Tefera, Tadesse Melaku Abegaz, Tamrat Befekadu Abebe, Abebe Basazn Mekuria
OBJECTIVE: The aim of this study was to assess the pattern of cardiovascular diseases (CVDs), their clinical characteristics, and associated factors in the outpatient department of the chronic illness clinic of Gondar University Referral Hospital. METHOD: A retrospective cross-sectional study was conducted among patients on follow-up at the outpatient chronic illness clinic of the hospital from October 2010 to October 2015. The source population for the study included patients with a diagnosis of CVD whose medical records have the required socio-demographic information during the study period...
2017: Vascular Health and Risk Management
Frances Bunn, Anne-Marie Burn, Louise Robinson, Marie Poole, Greta Rait, Carol Brayne, Johan Schoeman, Sam Norton, Claire Goodman
OBJECTIVES: People living with dementia (PLWD) have a high prevalence of comorbidty. The aim of this study was to explore the impact of dementia on access to non-dementia services and identify ways of improving service delivery for this population. DESIGN: Qualitative study involving interviews and focus groups. Thematic content analysis was informed by theories of continuity of care and access to care. SETTING: Primary and secondary care in the South and North East of England...
January 18, 2017: BMJ Open
M A Cikrikcioglu, A A Ozdemir, Y Sekin, B Yalcin, M Altay, A Gundogdu, S N Erkal, R Kazancioglu, R Erkoc
AIM: Objective of the present study was to investigate whether calcium antagonist use is associated with lower hemoglobin levels and/or higher erythropoiesis stimulating agent (ESA) requirement in hemodialysis patients. METHODS: A total of 130 adult hemodialysis patients were classified into two groups based on calcium antagonist usage for a period of at least 3 months as calcium antagonist users and calcium antagonist non-users. The two groups were compared cross-sectionally in a retrospective manner in terms of demographics, chronic kidney disease aetiologies, Charlson's Comorbidty Index, blood pressure, type of dialysis access, interdialytic body weight gain, cardiothoracic index, complete blood count, biochemistry, regular medication use and consumption of ESA...
September 2015: Minerva Urologica e Nefrologica, the Italian Journal of Urology and Nephrology
F A Angarita, T Chesney, C Elser, A M Mulligan, D R McCready, J Escallon
BACKGROUND: Treatment of breast cancer in elderly women is limited by declining functional status and life expectancy. The impact of providing less aggressive treatment remains controversial. This study assessed the treatment patterns of elderly breast cancer patients. METHODS: Retrospective chart review of women ≥70 y with breast cancer treated between 2004 and 2011 at two large Canadian cancer centres. Tumour and treatment characteristics were collected across three subgroups: 70-74 y (n = 314), 75-79 y (n = 233), and ≥80 y (n = 219)...
May 2015: European Journal of Surgical Oncology
T Y Kuzan, E Koca, O Dizdar, C Arslan, T Eren, S Yalcin, N Kucukoztas, S Aksoy, S Rahatli, D S Dede, O Altundag, N Zengin, O Ozyilkan, K Altundag
PURPOSE: Breast cancer incidence increases in the elderly but data on treatment and outcomes of elderly patients is limited. We assessed the clinicopathological features and outcomes of our patients with breast cancer aged ≥80 years in comparison with their younger postmenopausal counterparts. METHODS: The records of 83 patients diagnosed with breast cancer after the age of 80 (group 1) between 2003 and 2011 in 4 different centers were retrospectively evaluated and the clinicopathological features and outcomes were assessed in comparison with a control group (group 2) of 249 patients aged between 60-70 years...
April 2013: Journal of B.U.ON.: Official Journal of the Balkan Union of Oncology
Amirhossein Modabbernia, Hossein Poustchi, Reza Malekzadeh
CONTEXT: We briefly reviewed the evidence on the association of hepatitis C (HCV) infection with several aspects of mental and psychosocial health. EVIDENCE ACQUISITION: Medline was searched with appropriate keywords. The primary sources were the systematic reviews. If systematic reviews were not available for a subject, then the most relevant and methodologically sound original studies were selected. RESULTS: HCV infection is associated with poorer health-related quality of life, and physical, mental, and social health...
January 2013: Hepatitis Monthly
Zia Ul-Haq, Daniel F Mackay, Elisabeth Fenwick, Jill P Pell
BACKGROUND: The prevalence of obesity is rising in Scotland and globally. Overall, obesity is associated with increased morbidity, mortality and reduced health-related quality of life. Studies suggest that "healthy obesity" (obesity without metabolic comorbidity) may not be associated with morbidity or mortality. Its impact on health-related quality of life is unknown. METHODS: We extracted data from the Scottish Health Survey on self-reported health-related quality of life, body mass index (BMI), demographic information and comorbidity...
2012: BMC Public Health
V Leonidaki, M Maliori
This contribution reviews the international literature about dual diagnosis, meaning patients who have simultaneously mental health problems and substance use disorders and discusses epidemiology, clinical characteristics, but primarily etiopathogenesis and different treatment models and interventions. The epidemiological data coming from large-scale studies in the general population in USA, Australia and UK demonstrate the close relationship between mental health problems and substance use disorders. Also, the results from Greek research projects support this close relationship, but their research designs have significant limitations...
January 2009: Psychiatrikē, Psychiatriki
Carlos Rodríguez Pascual, Emilio Paredes Galán, Jose Luis Gonzalez Guerrero, Rocio Menendez Colino, Pedro Abizanda Soler, Mercedes Hornillos Calvo, Juan Jose Solano Jaurieta, Jorge Manzarbeitia Arambarri, Jose Manuel Ribera Casado, Fernando Rodríguez-Artalejo
BACKGROUND: Disease management programmes (DMPs) have been shown to reduce hospital readmissions and mortality in adults with heart failure (HF), but their effectiveness in elderly patients or in those with major comorbidity is unknown. The Multicenter Randomised Trial of a Heart Failure Management Programme among Geriatric Patients (HF-Geriatrics) assesses the effectiveness of a DMP in elderly patients with HF and major comorbidity. METHODS/DESIGN: Clinical trial in 700 patients aged ≥ 75 years admitted with a primary diagnosis of HF in the acute care unit of eight geriatric services in Spain...
August 5, 2011: BMC Public Health
Sanne Jespersen, Ole S Søgaard, Henrik C Schønheyder, Michael J Fine, Lars Ostergaard
BACKGROUND: Legionella is a common cause of bacterial pneumonia. Community-acquired [CAL] and hospital-acquired legionellosis [HAL] may have different presentations and outcome. We aimed to compare clinical characteristics and examine predictors of mortality for CAL and HAL. METHODS: We identified hospitalized cases of legionellosis in 4 Danish counties from January 1995 to December 2005 using the Danish national surveillance system and databases at departments of clinical microbiology...
2010: BMC Infectious Diseases
Gildete Barreto Lopes, Maria Tereza Silveira Martins, Cácia Mendes Matos, Josete Leão de Amorim, Eneida Barreto Leite, Eva Alves Miranda, Antonio Alberto Lopes
OBJECTIVE: To compare men and women on chronic hemodialysis in relation to their scores in health-related quality of life (HRQOL) and evaluate the potential influence of age and comorbidities on the comparison. METHODS: Cross-section of the baseline data of 254 women and 349 men, participants of the PROHEMO Study that has been developed in dialysis units of Salvador. By using the version of the Kidney Disease Quality of Life Short Form KDQOL-SF, validated for the Brazilian population, the following scores were determined: physical component summary (PCS), mental component summary [MCS] and the scale for symptoms/problems related to renal disease...
November 2007: Revista da Associação Médica Brasileira
J Isenegger, K Nedeltchev, M Arnold, U Fischer, G Schroth, L Remonda, H P Mattle
BACKGROUND: In selected stroke centers intra-arterial thrombolysis (IAT) is used for the treatment of acute stroke patients presenting within 6 hours of symptom onset. However, data about eligibility of acute stroke patients for IAT in clinical practice are very scarce. METHODS: We collected prospectively data on indications advising for or against IAT of 230 consecutive stroke patients in a tertiary stroke center. RESULTS: 76 patients (33...
December 2006: Journal of Neurology
Mary B Boyd, Marlene C Mackey, Kenneth D Phillips, Abbas Tavakoli
African-American women report less alcohol and drug (AOD) use than Caucasian women. However, African-Americans disproportionately experience negative health and social consequences of AOD use. This is especially true for rural women, many of whom live in poverty and have debilitating co-morbid psychiatric disorders that go undiagnosed and treated. It is imperative that health professionals be knowledgeable about AOD use, co-morbid disorders, and how to screen for them. This manuscript is focused on examining rural African American women (n = 142) with and without AOD disorders on the following variables: drugs of abuse, Axis I psychiatric disorder, and adult and childhood victimization...
December 2006: Issues in Mental Health Nursing
Christina Stadler, Martin Holtmann, Dieter Claus, Gerhard Büttner, Nicole Berger, Joachim Maier, Fritz Poustka, Klaus Schmeck
Attention deficit hyperactivity disorder (ADHD) persists into adulthood in about 30 to 50% of cases. Symptoms of ADHD in parents might affect effective therapeutic approaches in children. The objective of this study was to investigate (1) the retrospective rate of ADHD in biological parents of children with a diagnosis of ADHD, (2) the relation between retrospective ADHD symptomatology and current attention problems and impulsivity in parents, (3) whether the degree of ADHD severity and comorbidty in ADHD children depends on parental ADHD symptoms...
2006: Praxis der Kinderpsychologie und Kinderpsychiatrie
A R Lloyd
The subjective symptom of "fatigue" is one of the most widespread in the general population and is a major source of healthcare utilization. Prolonged fatigue is often associated with neuropsychological and musculoskeletal symptoms that form the basis of several syndromal diagnoses including chronic fatigue syndrome, fibromyalgia, and neurasthenia, and is clearly not simply the result of a lack of force generation from the muscle. Current epidemiologic research in this area relies predominantly on self-report data to document the prevalence and associations of chronic fatigue...
September 28, 1998: American Journal of Medicine
A Andreoli, S E Keller, M Rabaeus, L Zaugg, G Garrone, C Taban
Because recent research reports indicated clinical and biological differences in major depression with and without comorbid Diagnostic and Statistical Manual of Mental Disorders (DSM-III-R) panic disorder, and as altered immune measures were reported in selected subgroups of depressive patients, we investigated 51 pairs of major depressive episode (MDE) subjects, and gender- and age-matched healthy controls in order to determine if T lymphocytes number and function abnormalities were associated with Panic Disorder comorbidty...
May 1, 1992: Biological Psychiatry
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