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https://www.readbyqxmd.com/read/29679226/national-estimates-of-emergency-department-visits-for-antibiotic-adverse-events-among-adults-united-states-2011-2015
#1
Andrew I Geller, Maribeth C Lovegrove, Nadine Shehab, Lauri A Hicks, Mathew R P Sapiano, Daniel S Budnitz
BACKGROUND: Detailed, nationally representative data describing high-risk populations and circumstances involved in antibiotic adverse events (AEs) can inform approaches to prevention. OBJECTIVE: Describe US burden, rates, and characteristics of emergency department (ED) visits by adults for antibiotic AEs. DESIGN: Nationally representative, public health surveillance of adverse drug events (National Electronic Injury Surveillance System-Cooperative Adverse Drug Event Surveillance [NEISS-CADES]) and a nationally projected database of dispensed prescriptions (QuintilesIMS), 2011-2015...
April 20, 2018: Journal of General Internal Medicine
https://www.readbyqxmd.com/read/29674328/catastrophic-circulatory-collapse-after-inadvertent-subcutaneous-injection-of-treprostinil
#2
John J Radosevich, Mohan Dutt, Jeremy Feldman
PURPOSE: A case of life-threatening cardiovascular collapse after inadvertent subcutaneous injection of undiluted treprostinil is reported. SUMMARY: A 29-year-old, 76-kg woman with group 1 pulmonary arterial hypertension managed with subcutaneous treprostinil infusion arrived at the emergency department (ED) with headache, nausea, vomiting, and a syncopal episode. Her vital signs were stable on presentation. Admission orders were placed, and the appropriate 3-mL syringe containing 7...
April 19, 2018: American Journal of Health-system Pharmacy: AJHP
https://www.readbyqxmd.com/read/29673698/-which-information-is-given-during-the-purchase-of-an-hiv-self-test-in-a-caen-pharmacy-a-comprehensive-transversal-and-observational-study-using-surveys-without-modification-of-practice
#3
S Guitton, A Rabiaza
INTRODUCTION: HIV infection affects about 150,000 people in France. In total, 30,000 of them are unaware of their serostatus. In this context, HIV self-testing has arrived in France in September 2015. The aim of our study was to analyze the level of application of the recommendations during the purchase of an HIV self-test. Our primary hypothesis was that the delivered information is poor. METHODS: We realized a comprehensive transversal and observational study with surveys without modification of practice in all Caen pharmacies...
April 16, 2018: Annales Pharmaceutiques Françaises
https://www.readbyqxmd.com/read/29672671/adverse-events-associated-with-antibiotics-and-intravenous-therapies-for-post-lyme-disease-syndrome-in-a-commercially-insured-sample
#4
Kellie J Goodlet, Kathleen A Fairman
Background: Non-guideline endorsed post-treatment courses of antibiotics for post-Lyme disease syndrome (PLDS) have been linked to adverse patient outcomes, but these findings have yet to be validated in large systematic evaluations. Methods: A retrospective cohort analysis of medical and pharmacy claims derived from the Truven Health Market Scan® Commercial Claims and Encounters Database assessed 90-day incidence rates of adverse events (AEs) associated with PLDS treatments (PLDS-TX)...
April 17, 2018: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/29671885/-i-expected-just-to-walk-in-get-my-tablets-and-then-walk-out-on-framing-new-community-pharmacy-services-in-the-english-healthcare-system
#5
Asam Latif, Justin Waring, Deborah Watmough, Matthew J Boyd, Rachel A Elliott
Reconfiguration of the healthcare division of labour is becoming increasingly attractive in the context of increased patient demand and resource constraints. One example is the introduction of extended roles for pharmacists to provide patients additional support to manage their medicines, while also reducing work pressures experienced by other health professionals. Understanding how such policies are framed by those delivering and receiving care has been under-theorised. Using Goffman's frame theory, we examine one newly introduced community pharmacy service (New Medicines Service (NMS)) to illustrate how a policy intended to support patient medicine-taking through the extended roles of pharmacists is framed and where this deviates from its proposed aims...
April 19, 2018: Sociology of Health & Illness
https://www.readbyqxmd.com/read/29662890/harsh-working-conditions-and-poor-eating-habits-health-related-concerns-of-female-head-porters-kayayei-in-the-mallam-atta-market-accra-ghana
#6
Samuel Harrenson Nyarko, Abdul Majeed Tahiru
Background: The kaya business is known to pose significant health-related risks to female migrants. This study sought to explore the health-related concerns of female head porters in the Mallam Atta market, Accra, Ghana. Methods: A qualitative study was conducted in which twenty female head porters at the Mallam Atta market in Accra were interviewed. A thematic analysis was performed and the emerging themes were presented and supported with quotations from the respondents...
2018: BioMed Research International
https://www.readbyqxmd.com/read/29650726/reduction-of-healthcare-costs-through-a-transitions-of-care-program
#7
Weiyi Ni, Danielle Colayco, Jonathan Hashimoto, Kevin Komoto, Chandrakala Gowda, Bruce Wearda, Jeffrey McCombs
PURPOSE: Results of an evaluation of the impact of a pharmacy-based transitional care program on healthcare costs in a population of high-risk patients are reported. METHODS: A nonrandomized, observational cohort study was conducted to compare cost outcomes in a group of patients discharged from a single hospital who were referred to an ambulatory care pharmacy-based transitions-of-care (TOC) program and a control group of patients discharged from neighboring hospitals who received usual care; all patients were members of the same managed Medicaid plan...
April 12, 2018: American Journal of Health-system Pharmacy: AJHP
https://www.readbyqxmd.com/read/29649917/association-of-obesity-with-healthcare-resource-utilization-and-costs-in-a-commercial-population
#8
Pravin S Kamble, Jennifer Hayden, Jenna Collins, Raymond A Harvey, Brandon Suehs, Andrew Renda, Mette Hammer, Joanna Huang, Jonathan Bouchard
OBJECTIVE: To examine the association of obesity with healthcare resource utilization (HRU) and costs among commercially insured individuals. METHODS: This retrospective observational cohort study used insured individuals' administrative claims from 1/1/2007 to 12/1/2013. The ICD-9-CM status codes (V85 hierarchy) from 2008 to 2012 classified body mass index (BMI) into the World Health Organizations' BMI categories. The date of first observed BMI code was defined as the index date and continuous eligibility for one year pre- and post- index date was ensured...
April 12, 2018: Current Medical Research and Opinion
https://www.readbyqxmd.com/read/29621836/a-systematic-review-of-coding-systems-used-in-pharmacoepidemiology-and-database-research
#9
Yong Chen, Marko Zivkovic, Tongtong Wang, Su Su, Jianyi Lee, Edward A Bortnichak
BACKGROUND: Clinical coding systems have been developed to translate real-world healthcare information such as prescriptions, diagnoses and procedures into standardized codes appropriate for use in large healthcare datasets. Due to the lack of information on coding system characteristics and insufficient uniformity in coding practices, there is a growing need for better understanding of coding systems and their use in pharmacoepidemiology and observational real world data research. OBJECTIVES: To determine: 1) the number of available coding systems and their characteristics, 2) which pharmacoepidemiology databases are they adopted in, 3) what outcomes and exposures can be identified from each coding system, and 4) how robust they are with respect to consistency and validity in pharmacoepidemiology and observational database studies...
February 2018: Methods of Information in Medicine
https://www.readbyqxmd.com/read/29610252/enhancing-postdischarge-asthma-care-by-using-pharmacy-claims-and-telephone-follow-up
#10
Ronald J Teufel, Anita B Shuler, Myla D Ebeling, Kristen Morella, Annie L Andrews
BACKGROUND AND OBJECTIVES: Asthma is a common reason for hospital readmission. The majority of children are not receiving adequate preventive care after discharge. Our objective is to decrease return visits to the emergency department (ED) or hospital for asthma through a series of interventions (eg, access to real-time claims data and structured follow-up phone calls) designed to increase preventive care. METHODS: We performed a single-site quality improvement project for children 2 to 17 years old discharged with asthma from January 2010 to March 2014...
April 2, 2018: Hospital Pediatrics
https://www.readbyqxmd.com/read/29609221/accuracy-of-medication-information-sources-compared-to-the-best-possible-medication-history-for-patients-presenting-to-the-emergency-department
#11
Hayley H Chen, Simone E Taylor, Andrew M Harding, David McD Taylor
OBJECTIVE: To assess the accuracy of medication information sources available for adult patients presenting to the ED, compared to a best possible medication history (BPMH). METHODS: This prospective observational study was undertaken in the ED of a major tertiary-referral teaching hospital. A convenience sample of consecutive adult patients taking one or more regular medications was included. A BPMH was ascertained using patient/carer interviews, where available, and confirmed with one or more other sources...
April 2, 2018: Emergency Medicine Australasia: EMA
https://www.readbyqxmd.com/read/29606133/a-survey-of-pharmacists-perception-of-foundation-level-competencies-in-african-countries
#12
Arit Udoh, Andreia Bruno, Ian Bates
BACKGROUND: Evidence from published literature in pharmacy practice research demonstrate that the use of competency frameworks alongside standards of practice facilitate improvement in professional performance and aid expertise development. The aim of this study was to evaluate pharmacists' perception of relevance to practice of the competencies and behaviours contained in the FIP Global Competency Framework (GbCF v1). The overall objective of the study was to assess the validity of the GbCF v1 framework in selected countries in Africa...
April 2, 2018: Human Resources for Health
https://www.readbyqxmd.com/read/29600819/association-between-medication-adherence-and-the-outcomes-of-heart-failure
#13
Sarah R Hood, Anthony J Giazzon, Gwen Seamon, Kathleen A Lane, Jane Wang, George J Eckert, Wanzhu Tu, Michael D Murray
BACKGROUND: Previous studies of heart failure patients have demonstrated an association between cardiovascular medication adherence and hospitalizations or a composite end point of hospitalization and death. Few studies have assessed the impact of treatment adherence within large general medical populations that distinguish the health outcomes of emergency department visits, hospitalization, and death. OBJECTIVE: To determine the association of incremental cardiovascular medication adherence on emergency department visits, hospitalization, and death in adult heart failure patients in Indiana...
March 30, 2018: Pharmacotherapy
https://www.readbyqxmd.com/read/29575989/financial-impact-of-oral-chemotherapy-wastage-on-society-and-the-patient
#14
Varun Monga, Chenise Meyer, Brandon Vakiner, Gerald Clamon
Background Targeted oral agents are now increasingly being utilized in cancer treatment, but are expensive. Changing the dose of these medications due to toxicity or discontinuation secondary to disease progression or death causes waste from unused medication. Limiting waste is an important goal, as waste has a substantial financial impact on patients and insurance companies. Methods Patients started on oral targeted agents' sunitinib, everolimus, axitinib, or vemurafenib between January 2012 and February 2015 who obtained their medications at Holden Comprehensive Cancer Center specialty pharmacy were included in the analysis...
January 1, 2018: Journal of Oncology Pharmacy Practice
https://www.readbyqxmd.com/read/29572312/creating-organizational-value-by-leveraging-the-multihospital-pharmacy-enterprise
#15
Dan Schenkat, Steve Rough, Amanda Hansen, David Chen, Scott Knoer
PURPOSE: The results of a survey of multihospital pharmacy leaders are summarized, and a road map for creating organizational value with the pharmacy enterprise is presented. SUMMARY: A survey was designed to evaluate the level of integration of pharmacy services across each system's multiple hospitals, determine the most commonly integrated services, determine whether value was quantified when services were integrated, collect common barriers for finding value through integration, and identify strategies for successfully overcoming these barriers...
April 1, 2018: American Journal of Health-system Pharmacy: AJHP
https://www.readbyqxmd.com/read/29571273/economic-burden-of-skeletal-related-events-in-patients-with-multiple-myeloma-analysis-of-us-commercial-claims-database
#16
Debajyoti Bhowmik, Dionne M Hines, Michele Intorcia, Rolin L Wade
AIMS: To estimate incremental healthcare resource utilization (HRU) and costs associated with skeletal-related events (SREs) secondary to multiple myeloma (MM), and HRU and cost differences in patients with one vs multiple SREs. METHODS: Adults with MM diagnosis between January 1, 2010-December 31, 2014, with benefits coverage ≥12 months pre- and ≥6 months post-diagnosis were followed to last coverage date or December 31, 2015, excluding patients with prior anti-myeloma treatment or cancers...
April 12, 2018: Journal of Medical Economics
https://www.readbyqxmd.com/read/29566003/changes-and-specificities-in-health-behaviors-among-healthcare-students-over-an-8-year-period
#17
M P Tavolacci, J Delay, S Grigioni, P Déchelotte, J Ladner
BACKGROUND: Healthcare students are future health care providers and serve as role models and coaches to enhance behaviors for healthy lifestyles. However healthcare students face multiple stressors that could lead to adopting risk behaviors. OBJECTIVES: To assess the changes in health risk factors among healthcare students between 2007 and 2015, and to identify specific health behaviors based on the curriculum in a population of healthcare students. METHODS: Two cross sectionnal studies were conducted in 2007 and 2015 among nursing, medical, pharmacy, and physiotherapy students (Rouen, France)...
2018: PloS One
https://www.readbyqxmd.com/read/29554767/steroid-hormonal-bioactivities-culprit-natural-and-synthetic-hormones-and-other-emerging-contaminants-in-waste-water-measured-using-bioassays-and-uplc-tq-ms
#18
Corine J Houtman, Rob Ten Broek, Abraham Brouwer
Emission of compounds with biological activities from waste water treatment plant (WWTP) effluents into surface waters is a topic of concern for ecology and drinking water quality. We investigated the occurrence of hormone-like activities in waste water sample extracts from four Dutch WWTPs and pursued to identify compounds responsible for them. To this aim, in vitro reporter gene bioassays for androgenic, anti-androgenic, estrogenic, glucocorticoid and progestogenic activity and a UPLC-tQ-MS target analysis method for 25 steroid hormones used in high volumes in pharmacy were applied...
March 5, 2018: Science of the Total Environment
https://www.readbyqxmd.com/read/29553473/awareness-and-perceptions-of-emergency-contraceptive-pills-among-women-in-kinshasa-democratic-republic-of-the-congo
#19
Julie H Hernandez, Mbadu Muanda, Mélissa Garcia, Grace Matawa
CONTEXT: Despite the commitment of the Democratic Republic of the Congo (DRC) to expand the family planning method mix and increase access to services, awareness of emergency contraception is low among women, and the method remains underused and poorly integrated in family planning programming. METHODS: Data from 15 focus group discussions conducted in 2016 among women aged 15-35 were used to examine awareness and perceptions of, and attitudes toward, emergency contraceptives...
September 1, 2017: International Perspectives on Sexual and Reproductive Health
https://www.readbyqxmd.com/read/29542033/patients-perspective-of-the-impact-of-copd-on-quality-of-life-a-focus-group-study-for-patients-with-copd
#20
Anan Jarab, Eman Alefishat, Tareq Mukattash, Karem Alzoubi, Sharrel Pinto
Background The quality of life has been shown to be poor in patients with chronic obstructive pulmonary disease (COPD). Furthermore, patients' perspective and attitudes toward COPD and its impact on their quality of life have been remarkably ignored. Objective To explore patients' views and perceptions regarding COPD and its impact on their quality of life. Setting COPD clinic at the Royal Medical Services Hospital, Amman, Jordan. Method Focus groups discussions to explore patients' views and perceptions about COPD were conducted using purposive sampling technique till data saturation achieved...
March 14, 2018: International Journal of Clinical Pharmacy
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