keyword
MENU ▼
Read by QxMD icon Read
search

Paraquat

keyword
https://www.readbyqxmd.com/read/28808421/crosstalk-between-mitochondrial-fission-and-oxidative-stress-in-paraquat-induced-apoptosis-in-mouse-alveolar-type-ii-cells
#1
Guangju Zhao, Kaiqiang Cao, Changqin Xu, Aifang Sun, Wang Lu, Yi Zheng, Haixiao Li, Guangliang Hong, Bing Wu, Qiaomeng Qiu, Zhongqiu Lu
Paraquat (PQ), as a highly effective and nonselective herbicide, induces cell apoptosis through generation of superoxide anions which forms reactive oxygen species (ROS). Mitochondria, as regulators for cellular redox signaling, have been proved to play an important role in PQ-induced cell apoptosis. This study aimed to evaluate whether and how mitochondrial fission interacts with oxidative stress in PQ-induced apoptosis in mouse alveolar type II (AT-II) cells. Firstly, we demonstrated that PQ promoted apoptosis and release of cytochrome-c (Cyt-c)...
2017: International Journal of Biological Sciences
https://www.readbyqxmd.com/read/28806074/mechanical-bond-protected-air-stable-radicals
#2
Junling Sun, Zhichang Liu, Wei-Guang Liu, Yilei Wu, Yuping Wang, Jonathan C Barnes, Keith R Hermann, William A Goddard, Michael R Wasielewski, J Fraser Stoddart
Radical templation centered around a heterotrisradical tricationic inclusion complex DB(•+)⊂DAPQT(2(•+)), assembled from an equimolar mixture of a disubstituted 4,4'-bipyridinium radical cation (DB(•+)) and an asymmetric cyclophane bisradical dication (DAPQT(2(•+))), affords a symmetric [2]catenane (SC•7PF6) and an asymmetric [2]catenane (AC•7PF6) on reaction of the 1:1 complex with diazapyrene and bipyridine, respectively. Both these highly charged [2]catenanes have been isolated as air-stable mono-radicals and characterised by EPR spectroscopy...
August 14, 2017: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/28798883/magnetic-solid-phase-extraction-using-fe3o4-sio2-magnetic-nanoparticles-followed-by-uv-vis-spectrometry-for-determination-of-paraquat-in-plasma-and-urine-samples
#3
Ou Sha, Yu Wang, Xin Yin, Xiaobing Chen, Li Chen, Shujun Wang
A rapid and simple method was optimized and validated for the separation and quantification of paraquat, a frequently used herbicide and a leading cause of fatal poisoning worldwide, at trace levels with UV-Vis spectrophotometry in plasma and urine samples by direct magnetic solid-phase extraction. Fe3O4@SiO2 nanoparticles (NPs) were used as the magnetic solid-phase extraction agents and the paraquat absorbed on NPs was eluted using NaOH and ascorbic acid. Upon optimization, paraquat could be extracted and concentrated from various samples by 35-fold...
2017: Journal of Analytical Methods in Chemistry
https://www.readbyqxmd.com/read/28780814/-intervention-of-edaravone-against-renal-injury-induced-by-acute-paraquat-poisoning-in-rats
#4
S Zhang, Z X Chen, Y Y Jiang, Q Q Cai, Z H Yang, C R Wang, X Y Wu, P Ying, Z Q Lu
Objective: To investigate the dynamic change of paraquant-induced kidney injury in rats and the protective effect of edaravone. Methods: Eighty SD rats were randomly divided into 4 groups: the normal control group, paraquat poisoning group, edaravone treatment group and edaravone control group. The normal control group of 8 rats were given 1 ml of 0.9% sodium chloride through the abdominal cavity, and the same amount of fluid into the abdominal cavity after 30 minutes. The paraquat poisoning group of 24 rats were given 1 ml of paraquat solution (20 mg/kg) through the abdominal cavity to build poisoning models, and the same amount of 0...
June 20, 2017: Chinese Journal of Industrial Hygiene and Occupational Diseases
https://www.readbyqxmd.com/read/28780796/-changes-of-integrin-linked-kinase-expression-on-rats-pulmonary-fibrosis-induced-by-paraquat
#5
Y W Su, Y H Li, F Li, Y C Feng, H Huang, B X Wei, Y M Liu
Objective: To observe the expression of integrin-linked kinase on pulmonary fibrosis of paraquat (PQ) poisoning rats, and to discuss the relationship between ILK with pulmonary fibrosis induced by paraquat. Methods: Forty male Sprague-Dawley (SD) rats were randomly divided into control group and paraquat group, 20 in each group; the PQ group rats were intraperitoneally injected PQ liquid (18 mg/kg) , and the control group rats were injected the same volume of saline; 5 rats of these two groups were respectively sacrificed after 7, 14, 28, 56 days of PQ injection; according to the results of lung biopsy HE staining and Masson staining to observe the lung pathologic changes, measure the value of lung hydroxyproline and the expression of ILK...
May 20, 2017: Chinese Journal of Industrial Hygiene and Occupational Diseases
https://www.readbyqxmd.com/read/28780789/-the-study-of-using-salvianolate-treat-acute-lung-injury-in-rats-induced-by-paraquat
#6
Z W Wang, X X Li, X D Jian, Z C Zhang, B T Kan
Objective: To establish to paraquat poisoning acute lung injury animal model to study the therapeutic effect of Salvia polyphenols acid salt of paraquat-induced acute lung injury. Methods: Adult male Wister rats 120, were randomly divided into three groups: the paraquat exposure group, the start of the experiment to give a one-time 20% paraquat dope orally 50 mg/kg body weight of rats; salvianolate treatment group, the start of the experiment paraquat to give a one-time 20% the stock solution orally 50 mg/kg body weight of rats, and then given daily intraperitoneal injection of 200 mg/kg body weight of rats salvianolate; blank control group was given the same amount normal saline...
May 20, 2017: Chinese Journal of Industrial Hygiene and Occupational Diseases
https://www.readbyqxmd.com/read/28769783/age-and-chronicity-of-administration-dramatically-influenced-the-impact-of-low-dose-paraquat-exposure-on-behavior-and-hypothalamic-pituitary-adrenal-activity
#7
Chris A Rudyk, Jessica McNeill, Natalie Prowse, Zach Dwyer, Kyle Farmer, Darcy Litteljohn, Warren Caldwell, Shawn Hayley
Little is known of the age-dependent and long-term consequences of low exposure levels of the herbicide and dopaminergic toxicant, paraquat. Thus, we assessed the dose-dependent effects of paraquat using a typical short-term (3 week) exposure procedure, followed by an assessment of the effects of chronic (16 weeks) exposure to a very low dose (1/10th of what previously induced dopaminergic neuronal damage). Short term paraquat treatment dose-dependently induced deficits in locomotion, sucrose preference and Y-maze performance...
2017: Frontiers in Aging Neuroscience
https://www.readbyqxmd.com/read/28763046/increased-frequency-of-rheumatoid-arthritis-and-allergic-rhinitis-among-pesticide-sprayers-and-associations-with-pesticide-use
#8
Michalis Koureas, George Rachiotis, Andreas Tsakalof, Christos Hadjichristodoulou
Objective: The aim of this study was to identify diseases linked with the pesticide sprayer occupation and explore possible associations with exposure history data. Methods: Α cross sectional study was conducted among pesticide sprayers (n = 80) and the general population (n = 90) in Thessaly (Greece). Medical history, demographic characteristics and detailed exposure history were recorded by conducting personal interviews. Lifetime exposure indicators were calculated for several pesticide chemical subclasses...
August 1, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28759133/a-four-armed-unsymmetrical-cryptand-from-two-different-host-guest-interactions-to-responsive-supramolecular-polymer
#9
Chenhao Yao, Jing Zhang, Ming Cheng, Qiang Sun, Yi Pan, Juli Jiang, Leyong Wang
By linking BMP32C10 and DB24C8 motifs together, a four-armed cryptand 1 is synthesized successfully, in which BMP32C10 motif can bind paraquat 2 while DB24C8 motif can complex dibenzylammonium salt 3 in spite of the electrostatic repulsion between guests 2 and 3. The base/acid-responsive supramolecular polymer is constructed further via two kinds of host-guest interactions between cryptand 1 and two homoditopic paraquat 4 and dibenzylammonium salt 5 similar to guests 2 and 3.
July 31, 2017: Macromolecular Rapid Communications
https://www.readbyqxmd.com/read/28758742/effects-of-c-glycosides-from-apios-americana-leaves-against-oxidative-stress-during-hyperglycemia-through-regulating-mitogen-activated-protein-kinases-and-nuclear-factor-erythroid-2-related-factor-2
#10
Fujie Yan, Yunyun Yang, Lushuang Yu, Xiaodong Zheng
Main components of Apios americana leaves extract (ALE) were flavonoid C-glycosides, including vitexin (46.7%), schaftoside (18.9%), and orientin (4.32%). In vitro, ALE restored glucose consumption, glucose uptake, and glycogen content in glucose-induced hepatic cells. Exposure of HepG2 cells to high glucose resulted in reactive oxygen species and O2(-) accumulation, while ALE alleviated these increases by 47 ± 0.68 and 68 ± 0.74%, respectively. Glucose increased c-Jun N-terminal kinase (JNK) and decreased extracellular signal-regulated kinases 1 and 2 (ERK1/2) and p38 phosphorylation, while ALE reduced p-JNK and p-p38 but not p-ERK1/2, accompanied by nuclear factor erythroid 2-related factor 2 (Nrf2), heme oxygenase-1, and NAD(P)H quinine oxidoreductase 1 downregulation...
August 16, 2017: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/28757750/dialysis-catheter-related-pulmonary-embolism-in-a-patient-with-paraquat-intoxication
#11
Li-Keng Chao, Te-Chao Fang
A 30-year-old woman was sent to the emergency room after alcohol and paraquat ingestion. After three sessions of hemoperfusion via the indwelling double-lumen catheter, the patient could tolerate ambient air and her urine output was good. However, on the 10(th) day of hospitalization, she had a sudden onset of dyspnea and hypoxia. Pulmonary embolism was diagnosed by a computed tomography pulmonary angiogram. The patient recovered after anticoagulation therapy. We could find no reports of dyspnea caused by pulmonary embolism in patients with paraquat intoxication...
October 2016: Ci Ji Yi Xue za Zhi, Tzu-chi Medical Journal
https://www.readbyqxmd.com/read/28746171/the-value-of-apache-ii-in-predicting-mortality-after-paraquat-poisoning-in-chinese-and-korean-population-a-systematic-review-and-meta-analysis
#12
REVIEW
Jianshu Huang, Dandan Xuan, Xiuju Li, Li Ma, Yuanling Zhou, Hejian Zou
BACKGROUND: The Acute Physiology and Chronic Health Evaluation II (APACHE II) score is used to determine disease severity and predict outcomes in critically ill patients. However, the prognostic significance of APACHE after acute paraquat (PQ) poisoning remains unclear. The meta-analysis was aimed to study the value of APACHE II in predicting mortality in PQ-exposed Chinese and Korean patients. METHODS: Databases that included PubMed, Embase, Cochrane Library, and the Chinese National Knowledge Infrastructure were searched through August 2016...
July 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28744996/ion-pair-switchable-hydrophilicity-solvent-based-homogeneous-liquid-liquid-microextraction-for-the-determination-of-paraquat-in-environmental-and-biological-samples-before-high-performance-liquid-chromatography
#13
N Rahimi Kakavandi, M Ezoddin, K Abdi, M Ghazi-Khansari, M Amini, S J Shahtaheri
An approach involving ion-pair switchable-hydrophilicity solvent based homogeneous liquid-liquid microextraction coupled to high-performance liquid chromatography has been applied for the preconcentration and separation of paraquat in the real sample. A mixture of triethylamine and water was used as the switchable-hydrophilicity solvent. The pH was regulated using carbon dioxide; hence the ratio of the ionized and non-ionized form of triethylamine could control the optimum conditions. Sodium dodecyl sulfate was utilized as an ion-pairing agent...
July 26, 2017: Journal of Separation Science
https://www.readbyqxmd.com/read/28738607/novel-colorimetric-assay-for-paraquat-detection-on-silica-bead-using-negatively-charged-silver-nanoparticles
#14
Weena Siangproh, Thachkorn Somboonsuk, Orawan Chailapakul, Kriangsak Songsrirote
A simple, rapid, sensitive, and economical method based on colorimetry for the determination of paraquat, a widely used herbicide, was developed. Citrate-coated silver nanoparticles (AgNPs) were synthesized as the colorimetric probe. The mechanism of the assay is related to the aggregation of negatively charged AgNPs as induced by positively-charged paraquat resulting from coulombic attraction which causes the color to change from a deep greenish yellow to pale yellow in accordance with the concentrations of paraquat...
November 1, 2017: Talanta
https://www.readbyqxmd.com/read/28734097/first-report-of-ser653-asn-mutation-endowing-high-level-resistance-to-imazamox-in-downy-brome-bromus-tectorum-l
#15
Vipan Kumar, Prashant Jha
BACKGROUND: Bromus tectorum L. is one of the most troublesome grass weed species in cropland and non-cropland areas of the northwestern United States. In summer 2016, a B. tectroum accession (R) that survived imazamox at the field-use rate (44 g ha(-1) ) in an imidazolinone-tolerant (IMI-tolerant or Clearfield(™) ) winter wheat field was collected near Hammond, Carter County, MT, USA. The aim of this study was to determine the resistance profile of the B. tectroum R accession to imazamox and other ALS inhibitors, and investigate the mechanism of resistance to imazamox...
July 22, 2017: Pest Management Science
https://www.readbyqxmd.com/read/28731694/foliar-desiccators-glyphosate-carfentrazone-and-paraquat-affect-the-technological-and-chemical-properties-of-cowpea-grains
#16
Igor da Silva Lindemann, Gustavo Heinrich Lang, Jessica Fernanda Hoffmann, Cesar Valmor Rombaldi, Maurício de Oliveira, Moacir Cardoso Elias, Nathan Levien Vanier
The effects of the use of glyphosate (GLY), glyphosate plus carfentrazone (GLY/CAR), and paraquat (PAR) as plant desiccators on the technological and chemical properties of cowpea grains were investigated. All studied desiccants provided lower cooking time to freshly harvested cowpea. However, the coat color of PAR- and GLY/CAR-treated cowpea was reddish in comparison to the control treatment. Principal component analysis (PCA) from liquid chromatography-mass spectrometry (LC-MS) data sets showed a clear distinction among cowpea from the different treatments...
August 16, 2017: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/28719757/the-plasma-concentration-of-muc5b-is-associated-with-clinical-outcomes-in-paraquat-poisoned-patients
#17
Andrew A Monte, Hao Sun, Anna Malin Rapp-Olsson, Fahim Mohamed, Indika Gawarammana, Nicholas A Buckley, Christopher M Evans, Ivana V Yang, David A Schwartz
No abstract text is available yet for this article.
July 18, 2017: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/28714346/neuroprotective-effects-of-cassia-tora-against-paraquat-induced-neurodegeneration-relevance-for-parkinson-s-disease
#18
Sunil K Ravi, Ramesh B Narasingappa, Chandrashekar G Joshi, Talakatta K Girish, Bruno Vincent
The aim of the present study was to determine whether Cassia tora extracts could reverse the oxidative stress-induced neurodegeneration in a Parkinson's disease in vitro model. The leaves were treated with ethyl acetate (CtEA) or methanol (CtME). The extracts were first analysed by HPLC for their phenolic content and then tested for their neuroprotective effects in human SK-N-SH neuroblastoma cells. Cells were pre-treated with various concentrations of extracts followed by incubation with paraquat (14 μM)...
July 16, 2017: Natural Product Research
https://www.readbyqxmd.com/read/28713491/mulberry-anthocyanin-extract-ameliorates-oxidative-damage-in-hepg2-cells-and-prolongs-the-lifespan-of-caenorhabditis-elegans-through-mapk-and-nrf2-pathways
#19
Fujie Yan, Yushu Chen, Ramila Azat, Xiaodong Zheng
Mulberry anthocyanins possess many pharmacological effects including liver protection, anti-inflammation, and anticancer. The aim of this study was to evaluate whether mulberry anthocyanin extract (MAE) exerts beneficial effects against oxidative stress damage in HepG2 cells and Caenorhabditis elegans. In vitro, MAE prevented cytotoxicity, increased glucose consumption and uptake, and eliminated excessive intracellular free radicals in H2O2-induced cells. Moreover, MAE pretreatment maintained Nrf2, HO-1, and p38 MAPK stimulation and abolished upregulation of p-JNK, FOXO1, and PGC-1α that were involved in oxidative stress and insulin signalling modulation...
2017: Oxidative Medicine and Cellular Longevity
https://www.readbyqxmd.com/read/28704700/environmental-exposure-to-pesticides-and-the-risk-of-parkinson-s-disease-in-the-netherlands
#20
Maartje Brouwer, Anke Huss, Marianne van der Mark, Peter C G Nijssen, Wim M Mulleners, Antonetta M G Sas, Teus van Laar, Geert R de Snoo, Hans Kromhout, Roel C H Vermeulen
BACKGROUND: Exposure to pesticides has been linked to Parkinson's disease (PD), although associations between specific pesticides and PD have not been well studied. Residents of rural areas can be exposed through environmental drift and volatilization of agricultural pesticides. OBJECTIVES: Our aim was to investigate the association between lifetime environmental exposure to individual pesticides and the risk of PD, in a national case-control study. METHODS: Environmental exposure to pesticides was estimated using a spatio-temporal model, based on agricultural crops around the residential address...
July 10, 2017: Environment International
keyword
keyword
44684
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"