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https://www.readbyqxmd.com/read/27830204/outcomes-of-vitrectomy-membranectomy-and-internal-limiting-membrane-peeling-in-patients-with-refractory-diabetic-macular-edema-and-non-tractional-epiretinal-membrane
#1
Fariba Ghassemi, Fatemeh Bazvand, Ramak Roohipoor, Mehdi Yaseri, Narges Hassanpoor, Mohammad Zarei
PURPOSE: To evaluate the efficacy of vitrectomy, membranectomy, and internal limiting membrane (ILM) peeling on macular thickness and best corrected visual acuity (BCVA) in patients with refractory diffuse diabetic macular edema (DME) and non-tractional epiretinal membrane (NT-ERM). METHODS: This prospective interventional case series included eyes with refractory DME (central subfield macular thickness [CSMT] > 300 μm) after at least two intravitreal injections of bevacizumab (IVB) and one intravitreal injection of triamcinolone (IVT), and accompanying NT-ERM...
December 2016: Journal of Current Ophthalmology
https://www.readbyqxmd.com/read/27746298/long-term-outcomes-of-aflibercept-treatment-for-neovascular-age-related-macular-degeneration-in-a-clinical-setting
#2
Maria Eleftheriadou, Clara Vazquez-Alfageme, Cristina Maria Citu, Roxanne Crosby-Nwaobi, Sobha Sivaprasad, Philip Hykin, Robin D Hamilton, Praveen J Patel
PURPOSE: To report 2 year treatment outcomes with intravitreal aflibercept for neovascular age-related macular degeneration (nAMD) in routine clinical practice. DESIGN: Retrospective, non-randomized, interventional case series. METHODS: Retrospective analysis of electronic medical record (EMR) notes (OpenEyes), paper case notes and review of spectral-domain optical coherence tomography (SD-OCT) imaging of patients with consecutively treated eyes with previously untreated nAMD...
October 13, 2016: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/27699284/beyond-waste-new-sustainable-fillers-from-fly-ashes-stabilization-obtained-by-low-cost-raw-materials
#3
N Rodella, M Pasquali, A Zacco, F Bilo, L Borgese, N Bontempi, G Tomasoni, L E Depero, E Bontempi
A sustainable economy can be achieved only by assessing processes finalized to optimize the use of resources. Waste can be a relevant source of energy thanks to energy-from-waste processes. Concerns regarding the toxic fly ashes can be solved by transforming them into resource as recycled materials. The commitment to recycle is driven by the need to conserve natural resources, reduce imports of raw materials, save landfill space and reduce pollution. A new method to stabilize fly ash from Municipal Solid Waste Incinerator (MSWI) at room temperature has been developed thanks to COSMOS-RICE LIFE+ project (www...
September 2016: Heliyon
https://www.readbyqxmd.com/read/27696633/chiropractic-spinal-manipulative-therapy-for-migraine-a-three-armed-single-blinded-placebo-randomized-controlled-trial
#4
A Chaibi, J Š Benth, P J Tuchin, M B Russell
BACKGROUND AND PURPOSE: To investigate the efficacy of chiropractic spinal manipulative therapy (CSMT) for migraineurs. METHODS: This was a prospective three-armed, single-blinded, placebo, randomized controlled trial (RCT) of 17 months duration including 104 migraineurs with at least one migraine attack per month. The RCT was conducted at Akershus University Hospital, Oslo, Norway. Active treatment consisted of CSMT, whereas placebo was a sham push manoeuvre of the lateral edge of the scapula and/or the gluteal region...
October 2, 2016: European Journal of Neurology: the Official Journal of the European Federation of Neurological Societies
https://www.readbyqxmd.com/read/27628062/efficacy-of-fixed-dosing-aflibercept-for-treating-polypoidal-choroidal-vasculopathy-1-year-results-of-the-vault-study
#5
Joo Eun Lee, Jae Pil Shin, Hyun Woong Kim, Woohyok Chang, Yu Cheol Kim, Sang Joon Lee, In Young Chung, Ji Eun Lee
PURPOSE: To investigate fixed-dosing aflibercept for treating polypoidal choroidal vasculopathy (PCV). METHODS: This phase IV, prospective, single-arm, interventional case series was conducted in eight centers. Forty treatment-naïve PCV patients were administered three monthly doses of intravitreal aflibercept (2.0 mg) and an injection every 2 months thereafter. Best-corrected visual acuity (BCVA) and central subfield macular thickness (CSMT) were measured at each visit...
September 14, 2016: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/27579856/chemical-shift-magnetization-transfer-magnetic-resonance-imaging
#6
Weiguo Li, Xifu Wang, Frank H Miller, Andrew C Larson
PURPOSE: The purpose of this work was to develop a chemical shift magnetization transfer (CSMT) magnetic resonance imaging (MRI) method to provide accurate magnetization transfer ratio (MTR) measurements in the presence of fat. METHODS: Numerical simulations were performed to compare MTR measurements at different echo times (TEs) for voxels with varying fat/water content. The CSMT approach was developed using water fraction estimates to correct for the impact of fat signal upon observed MTR measurements...
August 31, 2016: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/27190126/effectiveness-and-safety-of-dexamethasone-implants-for-postsurgical-macular-oedema-including-irvine-gass-syndrome-the-episodic-2-study
#7
David Bellocq, Vincent Pierre-Kahn, Frédéric Matonti, Carole Burillon, Nicolas Voirin, Corinne Dot, Jad Akesbi, Solange Milazzo, Stéphanie Baillif, Vincent Soler, Benjamin Wolff, Claire Scemama, Ariane Malclès, Michel Weber, Laurent Kodjikian
AIM: To assess the effectiveness of intravitreal dexamethasone implants for treating postsurgical macular oedema (PSMO) including Irvine-Gass syndrome and determining the predictive factors of treatment response. METHODS: Descriptive, observational, retrospective, consecutive, uncontrolled, multicentre, national case series. One hundred patients were included between April 2011 and June 2014, with a minimum of 1-year follow-up. Patients received dexamethasone implant 0...
May 17, 2016: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/27013828/the-effect-of-intravitreal-bevacizumab-and-ranibizumab-on-macular-edema-of-the-contralateral-eye-a-comparative-study-of-two-anti-vegfs
#8
Berker Bakbak, Banu Turgut Ozturk, Saban Gonul, Sansal Gedik
PURPOSE: To compare the effects of bevacizumab and ranibizumab on the visual function and macular thickness in the contralateral (untreated) eye of patients with bilateral diabetic macular edema (DME). MATERIALS AND METHODS: Thirty-nine patients with bilateral DME, who had been treated with both bevacizumab and ranibizumab in the same eye, were considered retrospectively for this study. Recorded outcome measurements included the best-corrected visual acuity (BCVA) assessment with the Early Treatment Diabetic Retinopathy Study (ETDRS) chart and the central subfield macular thickness (CSMT) measurement of the contralateral, uninjected eye before and at 4 weeks after the injections...
January 2016: Oman Journal of Ophthalmology
https://www.readbyqxmd.com/read/26875003/a-crossover-design-for-comparative-efficacy-a-36-week-randomized-trial-of-bevacizumab-and-ranibizumab-for-diabetic-macular-edema
#9
RANDOMIZED CONTROLLED TRIAL
Henry E Wiley, Darby J S Thompson, Clare Bailey, Emily Y Chew, Catherine A Cukras, Glenn J Jaffe, Richard W J Lee, Erin K Loken, Catherine B Meyerle, Wai Wong, Frederick L Ferris
PURPOSE: To investigate the comparative efficacy of bevacizumab (Avastin) and ranibizumab (Lucentis; both Genentech, Inc, South San Francisco, CA) for diabetic macular edema (DME) using a crossover study design. DESIGN: Randomized, double-masked, 36-week, 3-period crossover clinical trial. PARTICIPANTS: Fifty-six subjects with DME involving the center of the macula in one or both eyes. METHODS: Monthly intravitreous injections of bevacizumab (1...
April 2016: Ophthalmology
https://www.readbyqxmd.com/read/26780119/photodynamic-therapy-in-vegf-inhibition-non-responders-pharmacogenetic-study-in-age-related-macular-degeneration-assessed-with-swept-source-optical-coherence-tomography
#10
Slawomir J Teper, Anna Nowinska, Jaroslaw Pilat, Edward Wylegala
BACKGROUND: Treatment of neovascular age-related macular degeneration (nAMD) remains a major challenge in ophthalmology. It is essential to determine which of VEGF inhibition non-responders can benefit from photodynamic therapy (PDT). As AMD is strongly related to gene polymorphisms, genetic factors can modify efficacy of treatment. Swept-source optical coherence tomography (SS-OCT) gives exceptional insight into the retina and choroid. SS-OCT usefulness needs to be evaluated in nAMD patients...
March 2016: Photodiagnosis and Photodynamic Therapy
https://www.readbyqxmd.com/read/26647210/endovascular-treatment-of-basilar-artery-thrombosis-secondary-to-bilateral-vertebral-artery-dissection-with-symptom-onset-following-cervical-spine-manipulation-therapy
#11
Ronni Mikkelsen, Rikke Beese Dalby, Niels Hjort, Claus Ziegler Simonsen, Sanja Karabegovic
BACKGROUND: Vertebral artery (VA) dissection (VAD) has been described following neck injury and can be associated with stroke, but the causal association with cervical spine manipulation therapy (cSMT) is controversial. The standard treatment for VAD is antithrombotic medical therapy. To highlight the considerations of an endovascular approach to VAD, we present a critical case of bilateral VAD causing embolic occlusion of the basilar artery (BA) in a patient with symptom debut following cSMT...
2015: American Journal of Case Reports
https://www.readbyqxmd.com/read/26586317/chiropractic-spinal-manipulative-therapy-for-migraine-a-study-protocol-of-a-single-blinded-placebo-controlled-randomised-clinical-trial
#12
RANDOMIZED CONTROLLED TRIAL
Aleksander Chaibi, Jūratė Šaltytė Benth, Peter J Tuchin, Michael Bjørn Russell
INTRODUCTION: Migraine affects 15% of the population, and has substantial health and socioeconomic costs. Pharmacological management is first-line treatment. However, acute and/or prophylactic medicine might not be tolerated due to side effects or contraindications. Thus, we aim to assess the efficacy of chiropractic spinal manipulative therapy (CSMT) for migraineurs in a single-blinded placebo-controlled randomised clinical trial (RCT). METHOD AND ANALYSIS: According to the power calculations, 90 participants are needed in the RCT...
November 19, 2015: BMJ Open
https://www.readbyqxmd.com/read/26430581/cervical-epidural-hematoma-after-chiropractic-spinal-manipulation-therapy-in-a-patient-with-an-undiagnosed-cervical-spinal-arteriovenous-malformation
#13
Meng Huang, Sean M Barber, Marc Moisi, Suzanne Powell, Andreana Rivera, Michael Zwillman, James Rose
Spinal epidural hematoma (SEH) occurring after chiropractic spinal manipulation therapy (CSMT) is a rare clinical phenomenon. Our case is unique because the patient had an undiagnosed cervical spinal arteriovenous malformation (AVM) discovered on pathological analysis of the evacuated hematoma. Although the spinal manipulation likely contributed to the rupture of the AVM, there was no radiographic evidence of the use of excessive force, which was seen in another reported case. As such, patients with a known AVM who have not undergone surgical intervention should be cautioned against symptomatic treatment with CSMT, even if performed properly...
2015: Curēus
https://www.readbyqxmd.com/read/26304635/changes-in-visual-acuity-after-idiopathic-epiretinal-membrane-removal-good-versus-poor-preoperative-visual-acuity
#14
Ik Soo Byon, Sung Ho Jo, Han Jo Kwon, Kyong Ho Kim, Sung Who Park, Ji Eun Lee
PURPOSE: To investigate postoperative visual acuity changes following idiopathic epiretinal membrane (ERM) surgery as well as investigate the relationship between outcome and baseline visual acuity. METHODS: The medical records of 159 consecutive eyes were retrospectively reviewed for best corrected visual acuity (BCVA), central subfield macular thickness (CSMT), and the ellipsoid zone (EZ) signal of the photoreceptor layer at baseline and 1, 3, and 6 months after surgery...
2015: Ophthalmologica. Journal International D'ophtalmologie
https://www.readbyqxmd.com/read/25583283/effectiveness-and-safety-of-dexamethasone-implants-for-post-surgical-macular-oedema-including-irvine-gass-syndrome-the-episodic-study
#15
MULTICENTER STUDY
David Bellocq, Jean-François Korobelnik, Carole Burillon, Nicolas Voirin, Corinne Dot, Eric Souied, John Conrath, Solange Milazzo, Pascale Massin, Stéphanie Baillif, Laurent Kodjikian
AIM: To assess the effectiveness and safety of intravitreal dexamethasone implants for treating post-surgical macular oedema, including Irvine-Gass syndrome refractory to first-line treatments. METHODS: Descriptive, observational, retrospective, consecutive, uncontrolled, multicentre, national case series. 50 patients were included in the study between March 2011 and June 2013 with a minimum 6 months follow-up. At baseline, each patient received a dexamethasone implant 0...
July 2015: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/25246208/-the-alteration-of-the-parameters-of-lipid-peroxidation-and-the-antioxidative-system-in-the-children-presenting-with-pyo-inflammatory-diseases-of-the-middle-ear
#16
S Kh Orziev, Kh É Karabaev, T S Saatov
The objective of the present study was to determine the amount of products of lipid peroxidation (dienic conjugates and malonic dialdehydes) together with antioxidative enzymes (catalase and superoxide dismutase) in 47 children presenting with acute pyo-inflammatory otitis media (APIOM) and 125 patients with chronic suppurative mesotympanitis (CSMT). In addition, 49 children presenting with chronic suppurative epitympanitis (CSET) and chronic suppurative epimesotympanitis (CSEMT) were included in the study...
2014: Vestnik Otorinolaringologii
https://www.readbyqxmd.com/read/25153659/epiretinal-membrane-peeling-after-uncomplicated-primary-retinal-detachment-repair
#17
Tanuj P Banker, Kyle W Godfrey, Gayatri S Reilly, Eric D Weichel
BACKGROUND AND OBJECTIVE: To identify rates and potential risk factors for epiretinal membrane (ERM) and for membrane peel (MP) after 23- or 25-gauge repair and to compare outcomes for eyes with ERM that underwent MP versus observation. PATIENTS AND METHODS: Review of 587 eyes with ERM after retinal detachment repair. Patients who developed ERM either underwent pars plana vitrectomy (PPV) and MP or were observed. RESULTS: Preoperatively, the PPV and MP group had a mean best corrected visual acuity (BCVA) of 20/100, compared to 20/40 for the observation group (P < ...
September 2014: Ophthalmic Surgery, Lasers & Imaging Retina
https://www.readbyqxmd.com/read/24942483/inertial-sensor-real-time-feedback-enhances-the-learning-of-cervical-spine-manipulation-a-prospective-study
#18
Antonio I Cuesta-Vargas, Jonathan Williams
BACKGROUND: Cervical Spinal Manipulation (CSM) is considered a high-level skill of the central nervous system because it requires bimanual coordinated rhythmical movements therefore necessitating training to achieve proficiency. The objective of the present study was to investigate the effect of real-time feedback on the performance of CSM. METHODS: Six postgraduate physiotherapy students attending a training workshop on Cervical Spine Manipulation Technique (CSMT) using inertial sensor derived real-time feedback participated in this study...
2014: BMC Medical Education
https://www.readbyqxmd.com/read/24852126/assessment-of-conditioning-specific-movement-tasks-and-physical-fitness-measures-in-talent-identified-under-16-year-old-rugby-union-players
#19
COMPARATIVE STUDY
Joanna R Parsonage, Rhodri S Williams, Paul Rainer, Ian McKeown, Morgan D Williams
Preparedness to train was assessed using a battery of conditioning-specific movement tasks (CSMTs) on a group of talent identified rugby union players (n = 156; age = 15 ± 7 years; stature = 176 ± 7 cm; and mass = 74 ± 14 kg). In addition to explore the link between movement competency and performance, a series of standard fitness tests was conducted. Overall the group's CSMTs competency ratings were low, but task dependent. The proportion of competent players ranged from 14% for a single leg squat to 70% for a double to single leg landing...
June 2014: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/24569581/association-of-serum-lipids-with-macular-thickness-and-volume-in-type-2-diabetes-without-diabetic-macular-edema
#20
Mariko Sasaki, Motoko Kawashima, Ryo Kawasaki, Atsuro Uchida, Takashi Koto, Hajime Shinoda, Kazuo Tsubota, Jie Jin Wang, Yoko Ozawa
PURPOSE: To assess the relationship between macular thickness and volume as characterized by optical coherence tomography (OCT) and known risk factors for diabetic retinopathy (DR) or macular edema (DME) in type 2 diabetic patients with no DME. METHODS: Seventy-four patients with type 2 diabetes without DME and no or only minimal DR (n = 67 with no DR; n = 7 with minimal DR; mean age, 59.5 years) were recruited at a tertiary eye hospital. Central subfield macular thickness (CSMT; circle of 500-μm radius) and central subfield macular volume (CSMV) were measured using spectral-domain OCT...
March 2014: Investigative Ophthalmology & Visual Science
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