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https://www.readbyqxmd.com/read/28815727/gender-disparities-among-patients-with-peripheral-arterial-disease-treated-via-endovascular-approach-a-propensity-score-matched-analysis
#1
Rajkumar Doshi, Priyank Shah, Perwaiz Meraj
BACKGROUND: Remarkable improvement in the treatment of Peripheral Arterial Disease (PAD) has led to changes in revascularization strategies from traditional open surgery to less invasive endovascular management. However, few studies are available on gender disparities in patients with PAD treated via an endovascular approach. This study was designed to analyze gender related differences with respect to in-hospital outcomes in PAD patients. METHODS: Our data was obtained from National Inpatient Sample (NIS) 2012 through 2014...
August 16, 2017: Journal of Interventional Cardiology
https://www.readbyqxmd.com/read/28815083/routine-jejunostomy-tube-feeding-following-esophagectomy
#2
Teus J Weijs, Hanneke W J van Eden, Jelle P Ruurda, Misha D P Luyer, Elles Steenhagen, Grard A P Nieuwenhuijzen, Richard van Hillegersberg
BACKGROUND: Malnutrition is an important problem following esophagectomy. A surgically placed jejunostomy secures an enteral feeding route, facilitating discharge with home-tube feeding and long-term nutritional support. However, specific complications occur, and data are lacking that support its use over other enteral feeding routes. Therefore routine jejunostomy tube feeding and discharge with home-tube feeding was evaluated, with emphasis on weight loss, length of stay and re-admissions...
July 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28810909/a-multi-center-randomized-controlled-open-label-trial-evaluating-the-effects-of-eosinophil-guided-corticosteroid-sparing-therapy-in-hospitalised-patients-with-copd-exacerbations-the-cortico-steroid-reduction-in-copd-cortico-cop-study-protocol
#3
Pradeesh Sivapalan, Mia Moberg, Josefin Eklöf, Julie Janner, Jørgen Vestbo, Rasmus Rude Laub, Andrea Browatzki, Karin Armbruster, Jon Torgny Wilcke, Niels Seersholm, Ulla Møller Weinreich, Ingrid Louise Titlestad, Helle Frost Andreassen, Charlotte Suppli Ulrik, Uffe Bødtger, Thyge Lynghøj Nielsen, Ejvind Frausing Hansen, Jens Ulrik Stæhr Jensen
BACKGROUND: The most commonly applied treatment for acute exacerbations of chronic obstructive pulmonary disease (AECOPD) is a 5-day course of high-dose systemic corticosteroids. However, this treatment has not been shown to reduce mortality and can potentially have serious side effects. Recent research has shown that, presumably, only a subgroup of COPD patients identifieable by blood eosinophil count benefit from a rescue course of prednisolone. By applying a biomarker-guided strategy, the aim of this study is to determine whether it is possible to reduce the use of systemic corticosteroids in AECOPD without influencing the outcome...
August 15, 2017: BMC Pulmonary Medicine
https://www.readbyqxmd.com/read/28810192/vaginal-and-laparoscopic-hysterectomy-as-an-outpatient-procedure-a-systematic-review
#4
Suzanne J Dedden, Peggy M A J Geomini, Judith A F Huirne, Marlies Y Bongers
OBJECTIVES: Laparoscopic and vaginal hysterectomies are common gynaecological procedures. Same-day discharge is usual care in various gynaecological procedures like laparoscopic sterilisation and laparoscopic oophorectomies. In major procedures like vaginal or laparoscopic hysterectomy patients are usually admitted overnight. We systematically reviewed the literature to identify complications, risk factors for (re)admittance, financial consequences and patient satisfaction of same-day discharge after a vaginal or laparoscopic hysterectomy...
July 22, 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/28804877/validation-of-a-geriatric-trauma-prognosis-calculator-a-p-a-l-li-a-t-e-consortium-study
#5
Allyson C Cook, Bellal Joseph, M Jane Mohler, Kenji Inaba, Brandon R Bruns, Paul A Nakonezny, Jeff D Kerby, Karen J Brasel, Steven E Wolf, Joseph Cuschieri, M Elizabeth Paulk, Ramona L Rhodes, Scott C Brakenridge, A Peter Ekeh, Herb A Phelan
BACKGROUND/OBJECTIVES: The P.A.L.Li.A.T.E. (prognostic assessment of life and limitations after trauma in the elderly) consortium has previously created a prognosis calculator for mortality after geriatric injury based on age, injury severity, and transfusion requirement called the geriatric trauma outcome score (GTOS). Here, we sought to create and validate a prognosis calculator called the geriatric trauma outcome score ii (GTOS II) estimating probability of unfavorable discharge. DESIGN: Retrospective cohort...
August 14, 2017: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/28804011/functional-outcomes-subsequent-healthcare-utilization-and-mortality-of-stroke-postacute-care-patients-in-taiwan-a-nationwide-propensity-score-matched-study
#6
Li-Ning Peng, Wan-Hsuan Lu, Chih-Kuang Liang, Ming-Yueh Chou, Chih-Ping Chung, Shu-Ling Tsai, Zhi-Jun Chen, Fei-Yuan Hsiao, Liang-Kung Chen
OBJECTIVE: To evaluate the benefits of the national stroke postacute care (PAC) program on clinical outcomes and subsequent healthcare utilization. DESIGN: Propensity score-matched case-control study using the National Health Insurance data. PARTICIPANTS: A total of 1480 stroke cases receiving PAC services and 3159 matched controls with similar stroke severity but without PAC services. MEASUREMENTS: Demographic characteristics, functional outcomes (modified Rankin Scale, Barthel Index, Lawton-Brody Instrumental Activities of Daily Living, Functional Oral Intake Scale, Mini-Nutritional Assessment, Berg Balance Test, Usual Gait Speed Test, 6-Minute Walk Test, Fugl-Meyer Assessment (modified sensation and motor), Mini-Mental State Examination, Motor Activity Log, and the Concise Chinese Aphasia Test), subsequent healthcare utilization (90-day stroke re-admission and emergency department visits), and 90-day mortality...
August 10, 2017: Journal of the American Medical Directors Association
https://www.readbyqxmd.com/read/28800178/outcomes-of-catheter-ablation-of-ventricular-tachycardia-with-mechanical-hemodynamic-support-an-analysis-of-the-medicare-database
#7
Arash Aryana, André d'Avila, Christina L Cool, Marc A Miller, Fermin C Garcia, Gregory E Supple, Srinivas R Dukkipati, Dhanunjaya Lakkireddy, T Jared Bunch, Mark R Bowers, Padraig Gearoid O'Neill, Vivek Y Reddy, Francis E Marchlinski
INTRODUCTION: There is a paucity of data in favor of mechanical support during catheter ablation of ventricular tachycardia (VT). This study investigated the outcomes of VT ablation associated with mechanical support using percutaneous ventricular assist device (PVAD) versus intra-aortic balloon pump (IABP). METHODS AND RESULTS: We retrospectively examined the outcomes of patients who underwent VT ablation associated with PVAD versus IABP from 2010-2013, captured by the Medicare Inpatient Standard Analytic File database...
August 11, 2017: Journal of Cardiovascular Electrophysiology
https://www.readbyqxmd.com/read/28797783/results-of-prospective-randomized-open-label-non-inferiority-study-of-tbo-filgrastim-granix-%C3%A2-versus-filgrastim-neupogen-%C3%A2-in-combination-with-plerixafor-for-autologous-stem-cell-mobilization-in-patients-with-multiple-myeloma-or-non-hodgkin-lymphoma
#8
Pavan Kumar Bhamidipati, Mark A Fiala, Brenda J Grossman, John F DiPersio, Keith Stokerl-Goldstein, Feng Gao, Geoffrey L Uy, Peter Westervelt, Mark A Schroeder, Amanda F Cashen, Camille N Abboud, Ravi Vij
Autologous hematopoietic stem cell transplantation (Auto- HSCT) improves survival in multiple myeloma (MM) and Non-Hodgkin lymphoma (NHL). Traditionally, filgrastim (Neupogen® - recombinant G-CSF) has been used in as a single agent or in combination with plerixafor for stem cell mobilization for auto-HSCT. In Europe, recombinant G-CSF biosimilar (Tevagrastim®) is approved for various indications similar to reference filgrastim, including stem cell mobilization for auto-HSCT; However, tbo- Filgrastim (Granix®) is registered under original biologic application and is not approved for stem cell mobilization in the USA...
August 7, 2017: Biology of Blood and Marrow Transplantation
https://www.readbyqxmd.com/read/28790002/reduced-impact-of-smoking-status-on-30-day-complication-and-readmission-rates-after-elective-spinal-fusion-%C3%A2-3-levels-for-adult-spine-deformity-a-single-institutional-study-of-839-patients
#9
Aladine A Elsamadicy, Owoicho Adogwa, Amanda Sergesketter, Victoria D Vuong, Emily Lydon, Shay Behrens, Joseph Cheng, Carlos A Bagley, Isaac O Karikari
BACKGROUND: Smoking status has been shown to affect postoperative outcomes after surgery. The aim of this study is to determine if patients' smoking status impacts 30-day complication and re-admission rates after elective complex spinal fusion (≥3 levels). METHODS: The medical records of 839 adult spinal deformity patients undergoing elective complex spinal fusion (≥3 levels) at a major academic institution from 2005 to 2015 were reviewed. We identified 124(14...
August 5, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28774394/re-examination-of-the-best-trial-using-composite-outcomes-including-emergency-department-visits
#10
Li Shen, Pardeep S Jhund, Ulrik M Mogensen, Lars Køber, Brian Claggett, Jennifer K Rogers, John J V McMurray
OBJECTIVES: The influence of choice of endpoint on trial size, duration, and interpretation of results was examined in patients with heart failure who were enrolled in BEST (Beta-blocker Evaluation of Survival Trial). BACKGROUND: The choice of endpoints in heart failure trials has evolved over the past 3 decades. METHODS: In the BEST trial, we used Cox regression analysis to examine the effect of bucindolol on the current standard composite of cardiovascular death or heart failure hospitalization (CVD/HFH) compared with the original primary mortality endpoint and the expanded composite that included emergency department (ED) visits...
August 2017: JACC. Heart Failure
https://www.readbyqxmd.com/read/28764269/analysis-of-clinical-indicators-of-quality-in-patients-with-endotracheal-intubation
#11
Sulochana Dash, Sreelatha Balasubramanian
INTRODUCTION: Quality and safety in anaesthesia is usually monitored by analysis of perioperative mortality-morbidity and are influenced by anaesthetic and non-anaesthetic factors. AIM: This study was conducted to analyse the incidence of clinical indicators of quality in endotracheally intubated patients undergoing general abdominal surgeries and obstetric and gynaecological procedures under general anaesthesia and to determine contributing factors for the same...
June 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28757140/the-feasibility-safety-and-effectiveness-of-hysteroscopic-sterilization-compared-with-laparoscopic-sterilization
#12
Lina Antoun, Paul Smith, Janesh K Gupta, T Justin Clark
BACKGROUND: In contrast to conventional laparoscopic sterilization, newer hysteroscopic approaches avoid the need for hospital admission, general anesthesia, and prolonged recovery. However, there are concerns that the feasibility, safety, and efficacy of hysteroscopic sterilization may be lower than established laparoscopic sterilization. OBJECTIVE: We sought to evaluate the outcomes of hysteroscopic sterilization compared with laparoscopic sterilization in routine clinical practice in a comparative observational cohort study...
July 27, 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28755773/patient-adherence-to-multi-component-continuing-care-discharge-plans
#13
Steven L Proctor, Jaclyn L Wainwright, Philip L Herschman
Intuitively, it is assumed that greater patient adherence to treatment recommendations in substance use disorder (SUD) treatment is associated with favorable outcomes, but surprisingly, there is limited research systematically examining the adherence-outcome relationship in the context of the continuing care phase post-discharge from residential treatment. This study sought to determine the effect of adherence to multi-component continuing care plans on long-term outcomes among patients following the primary treatment episode...
September 2017: Journal of Substance Abuse Treatment
https://www.readbyqxmd.com/read/28755149/improving-quality-and-decreasing-cost-by-reducing-re-admissions-in-patients-undergoing-total-joint-arthroplasty
#14
REVIEW
Daniel S Sveom, Mary K Otteman, Kevin L Garvin
PURPOSE OF REVIEW: Total joint arthroplasty (TJA) has had an increased demand over the recent years. It is a successful procedure, and there are relatively few complications, but there is a high overall cost. There is a push to increase the quality of care, lessen complications, and decrease cost by reducing readmissions. This article will discuss the risk factors that can contribute to the complication and readmission rates following TJA. RECENT FINDINGS: Several risk factors have been found to contribute to the complication and readmission rates following a TJA...
July 28, 2017: Current Reviews in Musculoskeletal Medicine
https://www.readbyqxmd.com/read/28748652/bleeding-related-hospital-admissions-and-30-day-re-admissions-in-patients-with-nonvalvular-atrial-fibrillation-treated-with-dabigatran-versus-warfarin
#15
Wallis C Y Lau, Xue Li, Ian C K Wong, Kenneth K C Man, Gregory Y H Lip, Wai K Leung, Chung W Siu, Esther W Chan
BACKGROUND: Reducing 30-day hospital re-admission is a policy priority worldwide. Warfarin-related bleeding is among the most common cause of hospital admissions due to adverse drug events. Compared to warfarin, dabigatran achieve full anticoagulation effect more quickly following its initiation, hence may lead to early-onset bleeds. OBJECTIVES: To compare the incidence of bleeding-related hospital admissions and 30-day re-admissions with dabigatran versus warfarin in patients with nonvalvular atrial fibrillation (NVAF)...
July 27, 2017: Journal of Thrombosis and Haemostasis: JTH
https://www.readbyqxmd.com/read/28737996/integrating-palliative-and-oncology-care-for-patients-with-advanced-cancer-a-quality-improvement-intervention
#16
Laura C Hanson, Frances Collichio, Stephen A Bernard, William A Wood, Matt Milowsky, Erin Burgess, Crista J Creedle, Summer Cheek, Lydia Chang, Bhisham Chera, Alexandra Fox, Feng-Chang Lin
BACKGROUND: Practice guidelines recommend palliative care for patients with advanced cancer, but gaps in access and quality of care persist. OBJECTIVE: To increase goals-of-care (GOC) communication for hospitalized patients with Stage IV cancer. METHODS: An interdisciplinary team designed a quality improvement intervention to enhance oncology palliative care, including training in communication skills and triggers for palliative care consults...
July 24, 2017: Journal of Palliative Medicine
https://www.readbyqxmd.com/read/28714522/factors-associated-with-safe-early-discharge-after-trans-catheter-aortic-valve-implantation
#17
Omar Aldalati, Friedon Keshavarzi, Amit Kaura, Jonathan Byrne, Mehdi Eskandari, Ranjit Deshpande, Mark Monaghan, Olaf Wendler, Rafal Dworakowski, Philip Maccarthy
BACKGROUND: As transcatheter aortic valve replacement (TAVI) becomes more straightforward, a larger proportion of patients will be well enough to be discharged early. This study sought to characterise the clinical features that allowed patients to be discharged early after TAVI and to evaluate the safety of an early discharge policy. METHODS: All patients undergoing TAVI at the above cited centre from August 2007 to March 2015 were included in this study. Baseline characteristics, in-hospital outcomes, re-admissions and mortality were compared...
July 17, 2017: Cardiology Journal
https://www.readbyqxmd.com/read/28710742/inpatient-weight-curve-trajectory-as-a-prognostic-factor-among-adolescents-with-anorexia-nervosa-a-preliminary-report
#18
Adar Avnon, Naomi Orkaby, Arik Hadas, Uri Berger, Anat Brunstein Klomek, Silvana Fennig
OBJECTIVE: To investigate the predictive value of weight restoration trajectories for relapse within the first year after discharge from inpatient treatment among adolescents with AN. METHODS: Forty four inpatient adolescents (5 boys, 39 girls) aged 11-18 (M 14.85, SD 1.87) diagnosed with anorexia were assessed at admission and discharge from a general hospital inpatient ward. Re-hospitalizations within 1 year of discharge were recorded. Factors assessed included 1/BMI at admission, 2/BMI at discharge, 3/percent from target weight (PFTW) at discharge, 4/length of hospitalization, and 5/a weight restoration trajectory measuring weight drops during inpatient weight restoration (rates of negative cubic variation in body weight (NCV)...
July 14, 2017: Eating and Weight Disorders: EWD
https://www.readbyqxmd.com/read/28699849/protein-energy-wasting-significantly-increases-healthcare-utilization-and-costs-among-patients-with-chronic-kidney-disease-a-propensity-score-matched-cohort-study
#19
Chia-Ter Chao, Chao-Hsiun Tang, Rhoda Wen-Yi Cheng, Michael Yao-Hsien Wang, Kuan-Yu Hung
BACKGROUND: Disease-related malnutrition is highly prevalent, and has prognostic implications for patients with chronic kidney disease (CKD); however, few studies have investigated the impact of malnutrition, or protein-energy wasting (PEW), on healthcare utilization and medical expenditure among CKD patients. METHODS: Using claim data from the National Health Insurance in Taiwan, this study identified patients with CKD between 2009-2013 and categorized them into those with mild, moderate, or severe CKD...
July 31, 2017: Current Medical Research and Opinion
https://www.readbyqxmd.com/read/28690311/predictors-of-long-term-mortality-and-frequent-re-hospitalization-in-patients-with-acute-decompensated-heart-failure-and-kidney-dysfunction-treated-with-renin-angiotensin-system-blockers
#20
Canan Baydemir, Dilek Ural, Kurtuluş Karaüzüm, Sibel Balci, Onur Argan, Irem Karaüzüm, Güliz Kozdağ, Ayşen A Ağır
BACKGROUND Assessment of risk for all-cause mortality and re-hospitalization is an important task during discharge of acute heart failure (AHF) patients, as they warrant different management strategies. Treatment with optimal medical therapy may change predictors for these 2 end-points in AHF patients with renal dysfunction. The aim of this study was to evaluate the predictors for long-term outcome in AHF patients with kidney dysfunction who were discharged on optimal medical therapy. MATERIAL AND METHODS The study was conducted retrospectively...
July 10, 2017: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
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