keyword
MENU ▼
Read by QxMD icon Read
search

mettl2

keyword
https://www.readbyqxmd.com/read/28655767/three-distinct-3-methylcytidine-m-3-c-methyltransferases-modify-trna-and-mrna-in-mice-and-humans
#1
COMPARATIVE STUDY
Luang Xu, Xinyu Liu, Na Sheng, Kyaw Soe Oo, Junxin Liang, Yok Hian Chionh, Juan Xu, Fuzhou Ye, Yong-Gui Gao, Peter C Dedon, Xin-Yuan Fu
Chemical RNA modifications are central features of epitranscriptomics, highlighted by the discovery of modified ribonucleosides in mRNA and exemplified by the critical roles of RNA modifications in normal physiology and disease. Despite a resurgent interest in these modifications, the biochemistry of 3-methylcytidine (m(3)C) formation in mammalian RNAs is still poorly understood. However, the recent discovery of trm141 as the second gene responsible for m(3)C presence in RNA in fission yeast raises the possibility that multiple enzymes are involved in m(3)C formation in mammals as well...
September 1, 2017: Journal of Biological Chemistry
https://www.readbyqxmd.com/read/22977489/whole-rat-dna-array-survey-for-candidate-genes-related-to-hypertension-in-kidneys-from-three-spontaneously-hypertensive-rat-substrains-at-two-stages-of-age-and-with-hypotensive-induction-caused-by-hydralazine-hydrochloride
#2
Kosho Kinoshita, Mohammad Said Ashenagar, Masaki Tabuchi, Hideaki Higashino
Clarification of the genetic nature and more effective care for hypertension are required, given the high incidences of cardiovascular and cerebrovascular mortality. Thus, we surveyed candidate genes for hypertension with rat whole gene DNA microarrays using three novel methods. Gene expression analyses were conducted as follows: Method 1, three types of spontaneously hypertensive rat (SHR) substrains, SHR, stroke-prone SHR (SHRSP) and malignant type of SHRSP (M-SHRSP) were used and compared to normotensive Wistar Kyoto rats; Method 2, the expressed genes between rats of different ages were compared for different blood pressures; and Method 3, genes that were expressed in rats treated with or without an acute hypotensive stimulus, the antihypertensive hydralazine hydrochloride, were compared...
March 2011: Experimental and Therapeutic Medicine
1
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"