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https://www.readbyqxmd.com/read/28489702/the-minimal-clinically-important-difference-for-the-mayo-portland-adaptability-inventory
#1
James F Malec, Jacob Kean, Patrick O Monahan
OBJECTIVES: To determine the Minimal Clinically Important Difference (MCID) and Robust Clinically Important Difference (RCID) of the Mayo-Portland Adaptability Inventory-4 (MPAI-4) as measures of response to intervention. METHODS: Retrospective analysis of existing data. Both distribution- and anchor-based methods were used to triangulate on the MCID and to identify a moderate, that is, more robust, level of change (RCID) for the MPAI-4. These were further evaluated with respect to clinical provider ratings...
November 8, 2016: Journal of Head Trauma Rehabilitation
https://www.readbyqxmd.com/read/28482762/power-training-in-chronic-stroke-individuals-differences-between-responders-and-nonresponders
#2
Stacey E Aaron, Jennifer L Hunnicutt, Aaron E Embry, Mark G Bowden, Chris M Gregory
BACKGROUND: Lower extremity muscle weakness is a primary contributor to post-stroke dysfunction. Resistance training is an effective treatment for hemiparetic weakness and improves walking performance. Post-stroke subject characteristics that do or do not improve walking speed following resistance training are unknown. OBJECTIVE: The purpose of this paper was to describe baseline characteristics, as well as responses to training, associated with achieving a minimal clinically important difference (MCID) in walking speed (≥0...
May 8, 2017: Topics in Stroke Rehabilitation
https://www.readbyqxmd.com/read/28477343/mindfulness-based-cognitive-therapy-mbct-is-cost-effective-compared-to-a-wait-list-control-for-persistent-pain-in-women-treated-for-primary-breast-cancer-results-from-a-randomized-controlled-trial
#3
M Johannsen, J Sørensen, M O'Connor, A B Jensen, R Zachariae
OBJECTIVE: To investigate the cost-effectiveness of Mindfulness-Based Cognitive Therapy (MBCT) com- pared to a wait-list control group for pain in women treated for breast cancer. METHODS: A total of 129 women were randomly allocated to MBCT or a wait-list control group. The primary outcome was the Minimal Clinically Important Difference (MCID) on pain intensity (>2 point reduction on an 11-point Numeric Rating Scale). Analyses were conducted from the healthcare system perspective and included data on healthcare utilization and pain medication retrieved from national registries for the period from baseline (T1) to 6 months post-intervention (T4)...
May 5, 2017: Psycho-oncology
https://www.readbyqxmd.com/read/28476369/editorial-commentary-pain-and-stress-response-after-shoulder-arthroscopic-rotator-cuff-repair-does-interscalene-block-make-a-clinically-important-difference
#4
EDITORIAL
Michael J Rossi
Pain control after arthroscopic rotator cuff repair will invariably encompass a multimodal approach which will include, in some form, an anesthetic block. The authors of "Effects of a Single-Dose Interscalene Block on Pain and Stress Biomarkers in Patients Undergoing Arthroscopic Rotator Cuff Repair: A Randomized Controlled Trial" demonstrate better pain control and a decrease in levels of the stress biomarker insulin with the use of a single-dose interscalene block (SISB) and general anesthesia compared to general anesthesia alone...
May 2017: Arthroscopy: the Journal of Arthroscopic & related Surgery
https://www.readbyqxmd.com/read/28474152/free-vascularized-fibular-grafting-improves-vascularity-compared-with-core-decompression-in-femoral-head-osteonecrosis-a-randomized-clinical-trial
#5
Lu Cao, Changan Guo, Jifei Chen, Zenggan Chen, Zuoqin Yan
BACKGROUND: Management of osteonecrosis of the femoral head remains challenging. Core decompression and free vascularized fibular grafting are commonly used surgical procedures for treatment of osteonecrosis of the femoral head. Few studies, however, have compared these two procedures in a randomized controlled study, in terms of improved vascularity of the femoral head, progression of disease, or hip scores. QUESTION/PURPOSES: (1) What is the effect of core decompression and fibular grafting on vascularity of the femoral head as measured by single-photon emission CT (SPECT)/CT? (2) Does one of these two methods lead to greater progression of Association Research Circulation Osseous (ARCO) stage as determined by serial MRI? (3) What is the relationship between the change in vascularity of the femoral head and hip function as measured by the Harris hip score (HHS) and progression to THA as an endpoint? METHODS: A randomized controlled trial was performed between June 2010 and October 2012 at Zhongshan Hospital, Fudan University...
May 4, 2017: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/28472071/associations-between-mri-features-versus-knee-pain-severity-and-progression-data-from-the-vancouver-longitudinal-study-of-early-knee-osteoarthritis
#6
Eric C Sayre, Ali Guermazi, John M Esdaile, Jacek A Kopec, Joel Singer, Anona Thorne, Savvas Nicolaou, Jolanda Cibere
OBJECTIVE: To determine associations between features of osteoarthritis (OA) on MRI and knee pain severity and knee pain progression. DESIGN: Baseline, 3.3- and 7.5-year assessments were performed for 122 subjects with baseline knee pain (age 40-79), sample-weighted for population (with knee pain) representativeness. MRIs were scored for: osteophytes (0:absent to 3:large); cartilage (0:normal to 4:full thickness defect; 0/1 collapsed); subchondral sclerosis (0:none to 3:>50% of site), subchondral cyst (0:absent to 3:severe), bone marrow lesions (0:none to 3:≥50% of site); and meniscus (0:normal to 3:maceration/resection), in 6-8 regions each...
2017: PloS One
https://www.readbyqxmd.com/read/28465722/does-partial-coating-with-titanium-improve-the-radiographic-fusion-rate-of-empty-peek-cages-in-cervical-spine-surgery-a-comparative-analysis-of-clinical-data
#7
Andreas Kotsias, Sven Mularski, Björn Kühn, Michael Hanna, Olaf Suess
BACKGROUND: Anterior cervical diskectomy and fusion (ACDF) is a well-established surgical treatment. Several types of intervertebral spacers can be used, but there is increasing evidence that PEEK cages yield insufficient fusion and thus less clinical improvement. The study aim was to assess the outcomes of single-level ACDF with an empty PEEK cage partially coated with titanium. METHODS: This prospective multicenter single-arm clinical study collected follow-up data at 6, 12, and 18 months...
2017: Patient Safety in Surgery
https://www.readbyqxmd.com/read/28457926/worker-s-compensation-status-and-outcomes-following-anterior-lumbar-interbody-fusion-alif-prospective-observational-study
#8
Kevin Phan, Simon Davies, Prashanth J Rao, Ralph J Mobbs
BACKGROUND: Anterior lumbar-interbody fusion (ALIF) is a common performed procedure for degenerative spinal disorders with reasonable clinical and safety outcomes, although there is limited evidence regarding the impact of ALIF in patients receiving worker's compensation (WC) compared to those without. The aim of our study is to identify whether WC status affects the clinical outcome and rates of complication following ALIF surgery in a prospective cohort. METHODS: 114 consecutive patients undergoing ALIF surgery from 2012-2014 were prospectively followed...
April 27, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28455737/treatment-of-irreparable-cuff-tears-with-smoothing-of-the-humeroscapular-motion-interface-without-acromioplasty
#9
Jason E Hsu, Jacob Gorbaty, Robert Lucas, Stacy M Russ, Frederick A Matsen
PURPOSE: We sought to determine whether shoulders with irreparable rotator cuff tears and retained active elevation can be durably improved using a conservative surgical procedure that smoothes the interface between the proximal humeral convexity and the concave undersurface of the coracoacromial arch followed by immediate range of motion exercises. METHODS: We reviewed 151 patients with a mean age of 63.4 (range 40-90) years at a mean of 7.3 (range 2-19) years after this surgery...
April 28, 2017: International Orthopaedics
https://www.readbyqxmd.com/read/28443164/single-level-minimally-invasive-transforaminal-lumbar-interbody-fusion-provides-sustained-improvements-in-clinical-and-radiological-outcomes-up-to-5-years-postoperatively-in-patients-with-neurogenic-symptoms-secondary-to-spondylolisthesis
#10
Hamid Rahmatullah Bin Abd Razak, Priyesh Dhoke, Kae-Sian Tay, William Yeo, Wai-Mun Yue
STUDY DESIGN: Retrospective review of prospective registry data. PURPOSE: To determine 5-year clinical and radiological outcomes of single-level instrumented minimally invasive transforaminal lumbar interbody fusion (MIS-TLIF) in patients with neurogenic symptoms secondary to spondylolisthesis. OVERVIEW OF LITERATURE: MIS-TLIF and open approaches have been shown to yield comparable outcomes. This is the first study to assess MIS-TLIF outcomes using the minimal clinically important difference (MCID) criterion...
April 2017: Asian Spine Journal
https://www.readbyqxmd.com/read/28441951/minimal-clinically-important-difference-for-the-6-min-walk-test-literature-review-and-application-to-morquio-a-syndrome
#11
REVIEW
Rudolf Schrover, Kathryn Evans, Roberto Giugliani, Ian Noble, Kaustuv Bhattacharya
Morquio A syndrome is an ultra-rare, inherited lysosomal storage disorder associated with progressive, multi-systemic clinical impairments, causing gradual loss of functional capacity and endurance, impaired quality of life, and early mortality. Studies in Morquio A patients have used the 6-min walk test (6MWT) to assess functionality and endurance and to evaluate disease progression or efficacy of treatment. The objective of the present study was to review minimal clinically important differences (MCIDs) for the 6MWT reported for disease states that widely use the 6MWT to evaluate clinical benefit and to discuss the results in view of the challenges in estimating MCID for ultra-rare diseases, using the case of elosulfase alfa in Morquio A patients...
April 26, 2017: Orphanet Journal of Rare Diseases
https://www.readbyqxmd.com/read/28433323/is-there-a-clinically-meaningful-difference-in-patient-reported-dyspnea-in-acute-heart-failure-an-analysis-from-urgent-dyspnea
#12
Peter S Pang, Kathleen A Lane, Miguel Tavares, Alan B Storrow, Changyu Shen, W Frank Peacock, Richard Nowak, Alexandre Mebazaa, Said Laribi, Judd E Hollander, Mihai Gheorghiade, Sean P Collins
BACKGROUND: Dyspnea is the most common presenting symptom in patients with acute heart failure (AHF), but is difficult to quantify as a research measure. The URGENT Dyspnea study compared 3 scales: (1) 10 cm VAS, (2) 5-point Likert, and (3) a 7-point Likert (both VAS and 5-point Likert were recorded in the upright and supine positions). However, the minimal clinically important difference (MCID) to patients has not been well established. METHODS: We performed a secondary analysis from URGENT Dyspnea, an observational, multi-center study of AHF patients enrolled within 1 h of first physician assessment in the ED...
April 19, 2017: Heart & Lung: the Journal of Critical Care
https://www.readbyqxmd.com/read/28431578/is-the-effectiveness-of-patellofemoral-bracing-modified-by-patellofemoral-alignment-and-trochlear-morphology
#13
Xi Zhang, Jillian P Eyles, Joanna Makovey, Matthew J Williams, David J Hunter
BACKGROUND: This study was performed to determine if the effectiveness of patellofemoral bracing as a treatment for patellofemoral osteoarthritis is influenced by patellofemoral joint alignment and trochlear morphology. We hypothesized that those with more extreme patellar malalignment would benefit more from bracing. METHODS: Thirty-eight patients who had received bracing as part of a comprehensive treatment plan for patellofemoral osteoarthritis were selected for this study...
April 21, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28394084/personalised-asthma-action-plans-for-adults-with-asthma
#14
REVIEW
Timothy L Gatheral, Alison Rushton, David Jw Evans, Caroline A Mulvaney, Nathan R Halcovitch, Gemma Whiteley, Fiona Jr Eccles, Sally Spencer
BACKGROUND: A key aim of asthma care is to empower each person to take control of his or her own condition. A personalised asthma action plan (PAAP), also known as a written action plan, an individualised action plan, or a self-management action plan, contributes to this endeavour. A PAAP includes individualised self-management instructions devised collaboratively with the patient to help maintain asthma control and regain control in the event of an exacerbation. A PAAP includes baseline characteristics (such as lung function), maintenance medication and instructions on how to respond to increasing symptoms and when to seek medical help...
April 10, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28376120/acupuncture-for-benign-prostatic-hyperplasia-a-systematic-review-and-meta-analysis
#15
Wei Zhang, Liyan Ma, Brent A Bauer, Zhishun Liu, Yao Lu
PURPOSE: This systematic review and meta-analysis aims to assess the therapeutic and adverse effects of acupuncture for benign prostatic hyperplasia (BPH) in randomized controlled trials (RCTs). METHODS: We searched the Cochrane Central Register of Controlled Trials (CENTRAL) in The Cochrane Library, MEDLINE, EMBASE, the Chinese Biomedical Database, the China National Knowledge Infrastructure, the VIP Database and the Wanfang Database. Parallel-group RCTs of acupuncture for men with symptomatic BPH were included...
2017: PloS One
https://www.readbyqxmd.com/read/28371025/treatment-response-to-sildenafil-in-men-with-erectile-dysfunction-relative-to-concomitant-comorbidities-and-age
#16
Irwin Goldstein, Vera Stecher, Martin Carlsson
AIM: To evaluate treatment response in men with erectile dysfunction (ED) and concomitant comorbidities. METHODS: Data were pooled from 42 placebo-controlled, flexible-dose sildenafil trials. In most trials, the sildenafil dose was 50 mg, taken ~1 hour before sexual activity but not more than once daily, with adjustment to 100 or 25 mg as needed. The overall population (N=9413) was stratified by age (<45, 46-64, ≥65 years). Treatment response was defined as a minimal clinically important difference (MCID) from baseline in the International Index of Erectile Function-Erectile Function (IIEF-EF) domain score of >2, >5 and >7 for men with mild, moderate and severe ED at baseline, respectively, or an IIEF-EF domain score ≥26 (no ED) at end-point...
March 2017: International Journal of Clinical Practice
https://www.readbyqxmd.com/read/28366584/control-of-allergic-rhinitis-and-asthma-test-for-children-caratkids-validation-in-brazil-and-cutoff-values
#17
Rita Amaral, Ana C Carneiro, Gustavo Wandalsen, João A Fonseca, Dirceu Sole
BACKGROUND: The Control of Allergic Rhinitis and Asthma Test for Children (CARATKids) assesses asthma and allergic rhinitis control in children younger than 12 years. OBJECTIVE: To validate the Brazilian Portuguese version of the CARATKids and to define the cutoff values for identifying uncontrolled disease. METHODS: Children aged 6 to 12 years with asthma and allergic rhinitis were studied (n = 102). CARATKids, childhood Asthma Control Test (cACT), total nasal symptom score (TNSS), and visual analog scale (VAS) scores were obtained at baseline and after 4 to 6 weeks...
May 2017: Annals of Allergy, Asthma & Immunology
https://www.readbyqxmd.com/read/28361468/impact-of-participation-in-the-adalimumab-humira-patient-support-program-on-rheumatoid-arthritis-treatment-course-results-from-the-passion-study
#18
Filip Van den Bosch, Andrew J K Ostor, Siegfried Wassenberg, Naijun Chen, Chen Wang, Vishvas Garg, Jasmina Kalabic
INTRODUCTION: Patients with rheumatoid arthritis (RA) who are treated with adalimumab (ADA) are offered a proprietary patient support program (PSP, AbbVie Care(®)). The main objective of this study was to examine the effectiveness of ADA on RA treatment course over time in the context of PSP utilization. METHODS: PASSION was a 78-week post-marketing observational study of RA patients with an insufficient response to ≥1 DMARD newly initiating ADA in routine clinical care that was conducted in Europe, Israel, Mexico, Puerto Rico, and Australia...
March 30, 2017: Rheumatology and Therapy
https://www.readbyqxmd.com/read/28357679/changes-in-quality-of-life-after-elective-surgery-an-observational-study-comparing-two-measures
#19
Vanessa L Kronzer, Michelle R Jerry, Arbi Ben Abdallah, Troy S Wildes, Sherry L McKinnon, Anshuman Sharma, Michael S Avidan
PURPOSE: Our main objective was to compare the change in a validated quality of life measure to a global assessment measure. The secondary objectives were to estimate the minimum clinically important difference (MCID) and to describe the change in quality of life by surgical specialty. METHODS: This prospective cohort study included 7902 adult patients undergoing elective surgery. Changes in the Veterans RAND 12-Item Health Survey (VR-12), composed of a physical component summary (PCS) and a mental component summary (MCS), were calculated using preoperative and postoperative questionnaires...
March 29, 2017: Quality of Life Research
https://www.readbyqxmd.com/read/28353050/do-surgeon-expectations-predict-clinically-important-improvements-in-womac-scores-after-tha-and-tka
#20
Hassan M K Ghomrawi, Carol A Mancuso, Allison Dunning, Alejandro Gonzalez Della Valle, Michael Alexiades, Charles Cornell, Thomas Sculco, Matthias Bostrom, David Mayman, Robert G Marx, Geoffrey Westrich, Michael O'Dell, Alvin I Mushlin
BACKGROUND: Failure of THA or TKA to meet a patient's expectations may result in patient disappointment and litigation. However, there is little evidence to suggest that surgeons can consistently anticipate which patients will benefit from those interventions. QUESTIONS/PURPOSES: To determine the ability of surgeons to identify, in advance of surgery, patients who will benefit from THA or TKA and those who will not, where 'benefit' is defined as a clinically important improvement in a validated patient-reported outcomes score...
March 28, 2017: Clinical Orthopaedics and related Research
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