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https://www.readbyqxmd.com/read/28096726/diffusion-weighted-mr-enterography-to-monitor-bowel-inflammation-after-medical-therapy-in-crohn-s-disease-a-prospective-longitudinal-study
#1
Jimi Huh, Kyung Jo Kim, Seong Ho Park, So Hyun Park, Suk-Kyun Yang, Byong Duk Ye, Sang Hyoung Park, Kyunghwa Han, Ah Young Kim
OBJECTIVE: To prospectively evaluate the performance of diffusion-weighted imaging (DWI) to monitor bowel inflammation after medical therapy for Crohn's disease (CD). MATERIALS AND METHODS: Before and following 1-2 years of medical therapy, between October 2012 and May 2015, 18 randomly selected adult CD patients (male:female, 13:5; mean age ± SD, 25.8 ± 7.9 years at the time of enrollment) prospectively underwent MR enterography (MRE) including DWI (b = 900 s/mm(2)) and ileocolonoscopy...
January 2017: Korean Journal of Radiology: Official Journal of the Korean Radiological Society
https://www.readbyqxmd.com/read/28094231/improving-efficiency-using-time-driven-activity-based-costing%C3%A2-methodology
#2
Laura C Tibor, Stacy R Schultz, Ronald Menaker, Bradley D Weber, Jay Ness, Paula Smith, Phillip M Young
PURPOSE: The aim of this study was to increase efficiency in MR enterography using a time-driven activity-based costing methodology. METHODS: In February 2015, a multidisciplinary team was formed to identify the personnel, equipment, space, and supply costs of providing outpatient MR enterography. The team mapped the current state, completed observations, performed timings, and calculated costs associated with each element of the process. The team used Pareto charts to understand the highest cost and most time-consuming activities, brainstormed opportunities, and assessed impact...
January 11, 2017: Journal of the American College of Radiology: JACR
https://www.readbyqxmd.com/read/28052284/asian-perspectives-on-diagnostic-and-therapeutic-strategies-in-inflammatory-bowel-disease-report-and-analysis-of-a-survey-with-questionnaires
#3
Atsushi Yoshida, Fumiaki Ueno, Toshio Morizane, Takashi Joh, Takeshi Kamiya, Shin''ichi Takahashi, Kengo Tokunaga, Ryuichi Iwakiri, Yoshikazu Kinoshita, Hidekazu Suzuki, Yuji Naito, Kazuhiko Uchiyama, Shin Fukodo, Francis K L Chan, Ki-Baik Halm, Udom Kachintorn, Kwong Ming Fock, Abdul Aziz Rani, Ari Fahrial Syam, Jose D Sollano, Qi Zhu
BACKGROUND: Diagnostic and therapeutic strategies in inflammatory bowel disease (IBD) vary among countries in terms of availability of modalities, affordability of health care resource, health care policy and cultural background. This may be the case in different countries in Eastern Asia. The aim of this study was to determine and understand the differences in diagnostic and therapeutic strategies of IBD between Japan and the rest of Asian countries (ROA). METHODS: Questionnaires with regard to clinical practice in IBD were distributed to members of the International Gastroenterology Consensus Symposium Study Group...
2017: Digestion
https://www.readbyqxmd.com/read/27943484/utility-of-mr-enterography-and-ultrasound-for-the-investigation-of-small-bowel-crohn-s-disease
#4
REVIEW
Gauraang Bhatnagar, Conrad Von Stempel, Steve Halligan, Stuart A Taylor
: Cross sectional Imaging plays an increasingly important role the diagnosis and management of Crohn's disease. Particular emphasis is placed on MRI and Ultrasound as they do not impart ionising radiation. Both modalities have reported high sensitivity for disease detection, activity assessment and evaluation of extra-luminal complications, and have positive effects on clinical decision making. International Guidelines now recommend MRI and Ultrasound in the routine management of Crohn's disease patients...
December 9, 2016: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/27930407/bowel-damage-in-crohn-s-disease-direct-comparison-of-ultrasonography-based-and-magnetic-resonance-based-lemann-index
#5
Antonio Rispo, Nicola Imperatore, Anna Testa, Pierpaolo Mainenti, Giovanni Domenico De Palma, Gaetano Luglio, Simone Maurea, Olga Maria Nardone, Nicola Caporaso, Fabiana Castiglione
BACKGROUND: The Lémann index (LI), calculated by magnetic resonance (MR) or computed tomography enterography in association with endoscopy, was developed to assess bowel damage (BD) in Crohn's disease (CD). Our aim was to investigate the concordance between ultrasonography-based Lèmann index (US-LI) and magnetic resonance-based Lèmann index (MR-LI). METHODS: We prospectively evaluated all consecutive patients with CD referred to our IBD Unit. All patients had undergone endoscopy, US and MR within 1 month...
January 2017: Inflammatory Bowel Diseases
https://www.readbyqxmd.com/read/27885894/mr-enterography-of-inflammatory-bowel-disease-with-endoscopic-correlation
#6
Pankaj Kaushal, Alexander S Somwaru, Aline Charabaty, Angela D Levy
Crohn disease (CD) and ulcerative colitis (UC) are the two main forms of idiopathic inflammatory bowel disease (IBD). CD is a transmural chronic inflammatory disorder that can affect any part of the gastrointestinal tract in a discontinuous distribution. UC is a mucosal and submucosal chronic inflammatory disease that typically originates in the rectum and may extend proximally in a continuous manner. In treating patients with CD and UC, clinicians rely heavily on accurate diagnoses and disease staging. Magnetic resonance (MR) enterography used in conjunction with endoscopy and histopathologic analysis can help accurately diagnose and manage disease in the majority of patients...
January 2017: Radiographics: a Review Publication of the Radiological Society of North America, Inc
https://www.readbyqxmd.com/read/27885892/invited-commentary-on-mr-enterography-of-inflammatory-bowel-disease-with-endoscopic-correlation
#7
Jeff L Fidler
No abstract text is available yet for this article.
January 2017: Radiographics: a Review Publication of the Radiological Society of North America, Inc
https://www.readbyqxmd.com/read/27874943/mr-enterography-with-diffusion-weighted-imaging-adc-values-in-normal-and-pathological-bowel-loops-a-possible-threshold-adc-value-to-differentiate-active-from-inactive-crohn-s-disease
#8
V Ninivaggi, M Missere, G Restaino, E Gangemi, M Di Matteo, A Pierro, G Sallustio, L Bonomo
OBJECTIVE: The aim of our study was to compare the apparent diffusion coefficient (ADC) values of pathological bowel loops wall (pADC) with the ADC values of normal appearing ones (naADC) and to determine a discriminating threshold. PATIENTS AND METHODS: 60 patients were studied at our Institution through a MR-enterography that included free-breathing axial Diffusion Weighted Imaging (DWI) with two b (0 and 800 s/mm2) after histological diagnosis of active Crohn's disease (CD)...
November 2016: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/27721092/accuracy-and-interobserver-agreement-of-diffusion-weighted-imaging-in-pediatric-inflammatory-bowel-disease
#9
Zehour AlSabban, Peter Church, Rahim Moineddin, Oscar M Navarro, Mary-Louise Greer, Thomas Walters, Govind B Chavhan
PURPOSE: To determine interobserver agreement (IOA) and accuracy of conventional MR enterography (MRE), qualitative diffusion, and apparent diffusion coefficient (ADC) values for detecting clinically active inflammation. METHODS: MREs in 57 consecutive children with suspected inflammatory bowel disease were retrospectively reviewed. RESULTS: Substantial IOA for conventional MRE (kappa=0.65) and qualitative diffusion (kappa=0.64), but fair to good IOA for ADC, (intra-class coefficient=0...
January 2017: Clinical Imaging
https://www.readbyqxmd.com/read/27709277/diffusion-weighted-mr-enterography-for-evaluating-crohn-s-disease-effect-of-anti-peristaltic-agent-on-the-diagnosis-of-bowel-inflammation
#10
So Hyun Park, Jimi Huh, Seong Ho Park, Seung Soo Lee, Ah Young Kim, Suk-Kyun Yang
OBJECTIVES: To prospectively investigate how Buscopan affects the diagnosis of bowel inflammation by diffusion-weighted imaging MR enterography (DWI-MRE) in Crohn's disease (CD). METHODS: Thirty CD patients without previous bowel surgery underwent DWI-MRE (b = 900 sec/mm(2)) before and after intravenous Buscopan. The 30 patients were randomly divided into two groups; using a crossover design, interpretations were made regarding the presence of restricted mural diffusion (i...
October 5, 2016: European Radiology
https://www.readbyqxmd.com/read/27687769/ultrasound-and-mri-predictors-of-surgical-bowel-resection-in-pediatric-crohn-disease
#11
Daniel G Rosenbaum, Maire A Conrad, David M Biko, Eduardo D Ruchelli, Judith R Kelsen, Sudha A Anupindi
BACKGROUND: Imaging predictors for surgery in children with Crohn disease are lacking. OBJECTIVE: To identify imaging features of the terminal ileum on short-interval bowel ultrasound (US) and MR enterography (MRE) in children with Crohn disease requiring surgical bowel resection and those managed by medical therapy alone. MATERIALS AND METHODS: This retrospective study evaluated patients 18 years and younger with Crohn disease undergoing short-interval bowel US and MRE (within 2 months of one another), as well as subsequent ileocecectomy or endoscopy within 3 months of imaging...
January 2017: Pediatric Radiology
https://www.readbyqxmd.com/read/27607894/the-accuracy-of-preoperative-imaging-in-measuring-the-length-of-the-ileocolic-segment-affected-by-crohn-s-disease-a-prospective-cohort-study
#12
Antoine Brouquet, Anne-Sophie Rangheard, Jonathan Ifergan, Thierry Lazure, Franck Carbonnel, Christophe Penna, Stéphane Benoist
AIM: The study aimed to evaluate the accuracy of imaging for the measurement of the length of the ileocolic segment affected by Crohn's disease. METHOD: Fifty-four consecutive patients who underwent resection between 2011 and 2014 for ileocolic Crohn's disease were prospectively studied. All had preoperative magnetic resonance (MR) or computed tomographic (CT) enterography. Two independent radiologists measured the length of the diseased intestinal segment. The measurements were compared with the length of disease assessed on pathology of the non-fixed surgical specimen...
September 8, 2016: Colorectal Disease: the Official Journal of the Association of Coloproctology of Great Britain and Ireland
https://www.readbyqxmd.com/read/27582877/magnetic-resonance-enterography-versus-capsule-endoscopy-activity-indices-for-quantification-of-small-bowel-inflammation-in-crohn-s-disease
#13
Uri Kopylov, Eyal Klang, Doron Yablecovitch, Adi Lahat, Benjamin Avidan, Sandra Neuman, Nina Levhar, Tomer Greener, Noa Rozendorn, Arkadi Beytelman, Henit Yanai, Iris Dotan, Yehuda Chowers, Batya Weiss, Shomron Ben-Horin, Marianne M Amitai, Rami Eliakim
BACKGROUND: Video capsule endoscopy (VCE) and magnetic resonance enterography (MRE) are the prime modalities for the evaluation of small bowel (SB) Crohn's disease (CD). Mucosal inflammation on VCE is quantified using the Lewis score (LS). Diffusion-weighted (DW) magnetic resonance imaging (MRI) allows for accurate assessment of SB inflammation without administration of intravenous contrast material. The Magnetic Resonance Index of Activity (MaRiA) and the Clermont index are quantitative activity indices validated for contrast-enhanced MRE and DW-MRE, respectively...
September 2016: Therapeutic Advances in Gastroenterology
https://www.readbyqxmd.com/read/27573371/extensive-heterotopic-gastric-mucosa-of-the-small-intestine-imaging-with-99m-tc-sodium-pertechnetate-spect-ct-enterography
#14
Andrew H Schapiro, Tom K Lin, Jason S Frischer, Ayaka Silverman, Andrew T Trout
Extensive heterotopic gastric mucosa of the small intestine is a rare, but potentially life-threatening condition characterized by multifocal or long-segment heterotopic gastric mucosa within the bowel lumen that is often associated with other anomalies including malrotation and annular pancreas. Although the imaging findings are characteristic, this entity may be unrecognized due to its unusual imaging appearance and rarity. CT or MR enterography and (99m)Tc-sodium pertechnetate scintigraphy can provide complementary information that enables specific diagnosis and accurate assessment of disease extent...
December 2016: Pediatric Radiology
https://www.readbyqxmd.com/read/27567607/diffusion-weighted-imaging-for-evaluating-inflammatory-activity-in-crohn-s-disease-comparison-with-histopathology-conventional-mri-activity-scores-and-faecal-calprotectin
#15
D A Pendsé, J C Makanyanga, A A Plumb, G Bhatnagar, D Atkinson, Manuel Rodriguez-Justo, S Halligan, S A Taylor
PURPOSE: To evaluate whether the extent of enteric diffusion-weighted imaging (DWI) signal abnormality reflects inflammatory burden in Crohn's disease (CD), and to compare qualitative and quantitative grading. METHODS: 69 CD patients (35 male, age 16-78) undergoing MR enterography with DWI (MRE-D) and the same-day faecal calprotectin (cohort 1) were supplemented by 29 patients (19 male, age 16-70) undergoing MRE-D and terminal ileal biopsy (cohort 2). Global (cohort 1) and terminal ileal (cohort 2) DWI signal was graded (0 to 3) by 2 radiologists and segmental apparent diffusion coefficient (ADC) calculated...
January 2017: Abdominal Radiology
https://www.readbyqxmd.com/read/27549100/findings-of-ulceration-and-severe-stricture-on-mre-can-predict-prognosis-of-crohn-s-disease-in-patients-treated-with-anti-tnf-treatment
#16
Makoto Naganuma, Shigeo Okuda, Tadakazu Hisamatsu, Katsuyoshi Matsuoka, Kiyoto Mori, Naoki Hosoe, Yoshihiro Nakazato, Haruhiko Ogata, Takanori Kanai
BACKGROUND: MR enterography (MRE) is useful for evaluating transmural lesions and extra-intestinal complications of Crohn's disease (CD). The aim of this study was to prospectively evaluate whether MRE could detect severe strictures and inflammatory lesions in patients who lost the responsiveness to anti-TNF treatment and whether MRE could predict prognosis of CD patients with clinical remission. PATIENTS AND METHODS: MRE were conducted in 50 patients who were treated with infliximab or adalimumab...
January 2017: Abdominal Radiology
https://www.readbyqxmd.com/read/27505635/dwi-in-pediatric-small-bowel-crohn-disease-are-apparent-diffusion-coefficients-surrogates-for-disease-activity-in-patients-receiving-infliximab-therapy
#17
Jonathan R Dillman, Ethan A Smith, Ramon Sanchez, Jeremy Adler, Soudabeh Fazeli, Bin Zhang, Matthew S Davenport
OBJECTIVE: The purpose of this study was to determine prospectively whether bowel wall apparent diffusion coefficient (ADC) measurements can be used to monitor treatment response to infliximab therapy in the setting of pediatric small-bowel Crohn disease. SUBJECTS AND METHODS: Twenty-eight pediatric subjects with newly diagnosed biopsy-proven Crohn disease of the distal or terminal ileum treated with infliximab were enrolled. Subjects underwent MR enterography at baseline, 1 month after therapy, and 6 months after therapy...
November 2016: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/27497037/detection-of-bowel-inflammation-with-fused-dwi-t2-images-versus-contrast-enhanced-images-in-pediatric-mr-enterography-with-histopathologic-correlation
#18
RANDOMIZED CONTROLLED TRIAL
Eric C Ehman, Andrew S Phelps, Michael A Ohliger, Sue J Rhee, John D MacKenzie, Jesse L Courtier
PURPOSE: To evaluate the fused, colorized diffusion weighted imaging (DWI) and anatomic T2 images compared to routine contrast-enhanced T1 images at pediatric magnetic resonance enterography (MRE). METHODS: Fused, colorized DWI/T2 images were created from patients with magnetic resonance enterography (MRE) and colonoscopy/biopsy. Radiologists noted inflammation in five bowel segments (terminal ileum-rectosigmoid colon) on postcontrast images and DWI/T2 images. Test characteristics and agreement were calculated...
November 2016: Clinical Imaging
https://www.readbyqxmd.com/read/27457791/caipirinha-accelerated-t1w-3d-flash-for-small-bowel-mr-imaging-in-pediatric-patients-with-crohn-disease-assessment-of-image-quality-and-diagnostic-performance
#19
Mengxia Li, Anke Dick, Nicole Hassold, Thomas Pabst, Thorsten Bley, Herbert Köstler, Henning Neubauer
BACKGROUND: The "Controlled Aliasing In Parallel Imaging Results In Higher Acceleration" (CAPIRINHA) technique greatly accelerates T1w 3D fast low angle shot (FLASH) scans while maintaining high image quality. We studied image quality and conspicuity of inflammatory lesions on CAIPIRINHA-accelerated imaging for pediatric small-bowel magnetic resonance imaging (MRI). METHODS: Forty-four consecutive patients (mean 14±3 years, 18 girls) underwent small-bowel MRI (MR enterography, MRE) at 1...
July 23, 2016: World Journal of Pediatrics: WJP
https://www.readbyqxmd.com/read/27448619/approach-to-the-patient-with-mild-crohn-s-disease-a-2016-update
#20
REVIEW
Frank I Scott, Gary R Lichtenstein
Mild Crohn's disease (CD) is classified as those patients who are ambulatory, with <10 % weight loss, are eating and drinking without abdominal mass, tenderness, obstructive symptoms, or fever, and endoscopically they have non-progressive mild findings. Initial evaluation of mild CD should focus on assessment for high-risk features requiring more aggressive therapy. In contrast to moderate-to-severe disease, where therapy is focused on mucosal healing, the management of mild CD is focused on symptom management, while exposing the individual to minimal therapeutic risks...
September 2016: Current Gastroenterology Reports
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