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MR enterography

Christopher G Roth, Dina Halegoua-De Marzio, Flavius F Guglielmo
MRI has transformed from the theoretical, investigative realm to mainstream clinical medicine over the past four decades and has become a core component of the diagnostic toolbox in the practice of gastroenterology (GI). Its success is attributable to exquisite contrast and the ability to isolate specific proton species through the use of different pulse sequences (i.e., T1-weighted, T2-weighted, diffusion-weighted) and exploiting extracellular and hepatobiliary contrast agents. Consequently, MRI has gained preeminence in various GI clinical applications: liver and pancreatic lesion evaluation and detection, liver transplantation evaluation, pancreatitis evaluation, Crohn's disease evaluation (using MR enterography) rectal cancer staging and perianal fistula evaluation...
March 16, 2018: Digestive Diseases and Sciences
I Thomassin-Naggara, S Bendifallah, P Rousset, M Bazot, M Ballester, E Darai
Diagnostic performance of MR imaging for the diagnosis of pelvic endometriosis are good. Even if some differences of performances exists according the location considered, the risk of misdiagnosis is lower than 10% for trained teams (NP2). The performance of pelvic MR imaging and surgery are quite similar to diagnose endometrioma (sensitivity and specificity>90%). A negative pelvic MR imaging allows to exclude deep pelvic endometriosis with a performance similar to surgery but a positive MR imaging is less accurate than surgery because of a high number of false positives (23%)...
March 11, 2018: Gynecologie, Obstetrique, Fertilite & Senologie
Michael Hunter Lanier, Anup S Shetty, Amber Salter, Geetika Khanna
BACKGROUND: Gadolinium deposition in normal tissues is being increasingly recognized. Children with inflammatory bowel disease (IBD) undergo frequent imaging with contrast-enhanced MR enterography (MRE). PURPOSE: To determine the impact of intravenous (IV) gadolinium in assessment of pediatric IBD by MRE. STUDY TYPE: Retrospective, case series. POPULATION: Radiology information system was searched to identify all children who underwent MRE and endoscopy within 30 days in 2016...
March 5, 2018: Journal of Magnetic Resonance Imaging: JMRI
H Schöllnast
BACKGROUND: During the course of the disease, chronic inflammatory bowel diseases (CIBD) show different activities, which-in addition to morphological changes-significantly influence the choice of therapy. OBJECTIVE: The value of imaging in characterization of the activity of inflammatory changes is evaluated. MATERIALS AND METHODS: In the present review of the current literature, indications, performance, and findings of imaging of inflammatory bowel disease and on the assessment of disease activity are assessed...
March 2, 2018: Der Radiologe
Catharina S de Jonge, Ruaridh M Gollifer, Aart J Nederveen, David Atkinson, Stuart A Taylor, Jaap Stoker, Alex Menys
OBJECTIVE: Dynamic imaging of small intestinal motility is an increasingly common research method to examine bowel physiology in health and disease. However, limited data exists to guide imaging protocols with respect to quantitative analysis. The purpose of this study is to define the required temporal resolution and scan duration in dynamic MRI for small bowel motility assessment. METHODS: 6 healthy volunteers underwent motility imaging with MR enterography using breath-hold protocol...
February 23, 2018: British Journal of Radiology
Yan Li, Karsten Beiderwellen, Felix Nensa, Johannes Grüneisen, Gustav Dobos, Ken Herrmann, Thomas Lauenstein, Lale Umutlu, Jost Langhorst
PURPOSE: To evaluate the diagnostic performance of integrated whole-body positron emission tomography (PET)/magnetic resonance (MR) enterography in patients with Crohn's disease (CD). METHODS: Fifty patients with known CD and recurrent symptoms underwent ileocolonoscopy (reference standard) as well as PET/MR enterography. Seven ileocolonic segments were endoscopically analysed using the Simplified Endoscopic Activity Score for Crohn's Disease (SES-CD) and additionally classified into three categories of inflammation (none, mild to moderate and severe ulcerative inflammation)...
February 17, 2018: European Journal of Nuclear Medicine and Molecular Imaging
Giuseppe Lo Re, Dario Picone, Federica Vernuccio, Laura Scopelliti, Ambra Di Piazza, Chiara Tudisca, Salvatore Serraino, Giambattista Privitera, Federico Midiri, Sergio Salerno, Massimo Midiri, Tommaso Vincenzo Bartolotta, Roberto Lagalla
Purpose: To evaluate and compare the mesenteric and bowel wall changes during Crohn's disease (CD) on ultrasonography (US) Strain Elastography (SE) and Enterography Magnetic Resonance Imaging (E-MRI). Methods: From July 2014 to September 2016, 35 patients with ileocolonoscopy diagnosis of CD were prospectively examined with E-MRI and in the same time with US and SE. Results: A total of 41 affected bowel segments and 35 unaffected bowel segments in 35 patients were evaluated...
2017: BioMed Research International
Huaijun Wang, Stephen A Felt, Ismayil Guracar, Valentina Taviani, Jianhua Zhou, Rosa Maria Silveira Sigrist, Huiping Zhang, Joy Liau, José G Vilches-Moure, Lu Tian, Yamil Saenz, Thierry Bettinger, Brian A Hargreaves, Amelie M Lutz, Jürgen K Willmann
OBJECTIVES: To evaluate the feasibility and time saving of fusing CT and MR enterography with ultrasound for ultrasound molecular imaging (USMI) of inflammation in an acute small bowel inflammation of swine. METHODS: Nine swine with ileitis were scanned with either CT (n = 3) or MR (n = 6) enterography. Imaging times to load CT/MR images onto a clinical ultrasound machine, fuse them to ultrasound with an anatomical landmark-based approach, and identify ileitis were compared to the imaging times without anatomical road mapping...
November 23, 2017: European Radiology
Zehour AlSabban, Nicholas Carman, Rahim Moineddin, Ryan T Lo, Sebastian K King, Jacob C Langer, Thomas D Walters, Anne M Griffiths, Peter C Church, Mary-Louise C Greer
BACKGROUND: Pediatric Crohn's disease is associated with perianal disease (PAD). Magnetic resonance enterography (MRE) assesses small bowel involvement in pediatric inflammatory bowel disease (PIBD). Pelvic MRI (P-MRI) is the gold standard for assessing PAD. PURPOSE: To determine if MRE can accurately detect PAD in PIBD, distinguishing perianal fistulae (PAF) from perianal abscesses (PAA), referenced against P-MRI. STUDY TYPE: Retrospective...
November 14, 2017: Journal of Magnetic Resonance Imaging: JMRI
David M Biko, Petar Mamula, Nancy A Chauvin, Sudha A Anupindi
OBJECTIVES: Identify MRE features of colonic strictures in children/young adults with Crohn's disease. METHODS: Included are patients with colonic strictures on colonoscopy imaged with MRE. Bowel wall thickening (BWT) with luminal narrowing, pre-stenotic dilatation (PSD), bowel wall enhancement, and diffusion restriction were evaluated. RESULTS: All potential strictures (n=12) had BWT with luminal narrowing on MRE. 8/12 had PSD, meeting our MRE stricture criteria...
October 20, 2017: Clinical Imaging
Hee Mang Yoon, Chong Hyun Suh, Jeong Rye Kim, Jin Seong Lee, Ah Young Jung, Kyung Mo Kim, Young Ah Cho
Importance: Magnetic resonance (MR) enterography has the advantage over other techniques of being noninvasive, lacking ionizing radiation, and demonstrating excellent soft-tissue contrast to evaluate pediatric patients with inflammatory bowel disease (IBD). Objective: To evaluate the diagnostic performance of MR enterography for detection of active inflammation in children and adolescents with known or suspected IBD. Data Sources: A search of MEDLINE and EMBASE up to January 2, 2017, was performed to identify studies...
December 1, 2017: JAMA Pediatrics
Rune Wilkens, Rikke H Hagemann-Madsen, David A Peters, Agnete H Nielsen, Charlotte B Nørager, Henning Glerup, Klaus Krogh
Background and Aims: Increased small intestinal wall thickness correlates with both inflammatory activity and fibrosis in Crohn's disease (CD). Assessment of perfusion holds promise as an objective marker distinguishing between the two conditions. Our primary aim was to determine if relative bowel wall perfusion measurements correlate with histopathological scores for inflammation or fibrosis in CD. Methods: Twenty-five patients were investigated prior to elective surgery for small intestinal CD...
August 3, 2017: Journal of Crohn's & Colitis
Johannes Boos, Jieming Fang, Christina M Chingkoe, Michele Perillo, Martin Smith, Vassilios Raptopoulos, Olga R Brook
OBJECTIVE: The purpose of this article is to evaluate the image quality and added value of split-bolus contrast agent injection combining late arterial and portal venous phases compared with single-bolus contrast agent injection late arterial phase CT enterography. MATERIALS AND METHODS: Consecutive patients who underwent CT enterography before and after implementation of a single-bolus CT enterography protocol were included. Attenuation and contrast-to-noise ratio (CNR) were assessed by ROI measurements of the bowel wall and arterial and venous structures...
November 2017: AJR. American Journal of Roentgenology
Jiyoung Hwang, Jin Sil Kim, Ah Young Kim, Joon Seok Lim, Se Hyung Kim, Min Ju Kim, Mi Sung Kim, Kyoung Doo Song, Ji Young Woo
AIM: To investigate the characteristic radiologic findings of cryptogenic multifocal ulcerous stenosing enteritis (CMUSE) which can be differentiated from other similar bowel disease and to assess their clinical behavior. METHODS: Twenty pathologically and clinically confirmed CMUSE patients (males:females = 8:12; mean age: 40.4 years) between March 2002 and August 2015 from seven academic centers in South Korea were retrospectively reviewed. We evaluated small bowel series (SBS; n = 25), computed tomography (CT) enterography (n = 21), magnetic resonance (MR) enterography (n = 2), and abdominopelvic CT (n = 18) images, focusing on enteric and perienteric manifestations...
July 7, 2017: World Journal of Gastroenterology: WJG
Emanuele Casciani, Giovanni Di Nardo, Simone Chin, Gabriele Masselli, Elisabetta Polettini, Salvatore Oliva, Denis A Cozzi, Salvatore Cucchiara, Gianfranco Gualdi
OBJECTIVES: To evaluate the performance of Magnetic Resonance enterography (MRE) in the diagnostic work-up of children presenting with obscure gastrointestinal bleeding (OGIB). MATERIALS AND METHODS: From January 2014 to January 2016, a single-centre prospective study was performed on all children between 0 and 16 years of age referred to the radiology department for OGIB. Each child underwent MRE examination after negative oesophagogastroduodenoscopy and ileocolonoscopy...
August 2017: European Journal of Radiology
Ayşe Erden, Sena Ünal, Habip Eser Akkaya, Mehmet Onay, Murat Törüner, Zeynep Bıyıklı Gençtürk, Aysun Çalışkan Kartal
OBJECTIVE: In this retrospective study, we aimed to evaluate MR enterography (MRE) findings, MR index of activity (MaRIA) and laboratory markers in Crohn patients with enteroenteric fistula. METHODS: Institution's electronic medical records (laboratory, pathology, ileocolonoscopy results and discharge summary) were reviewed and MR images retrieved from the PACS were reanalyzed in Crohn patients assessed at Gastroenterology Clinic of our university between July 2011 and July 2016...
September 2017: European Journal of Radiology
Seema Khanna, Piyush Gupta, Rahul Khanna, Disha Dalela
The postbulbar segment also known as the distal duodenum is a separate clinical entity in terms of the intrinsic pathologies of this region and its varied anatomical relations. The common bile duct and the pancreatic duct open through the major papilla, which marks the beginning of this segment. Distal duodenal obstruction can be defined as a clinicoradiological entity that is characterized by features of gastric outlet obstruction with recurrent bilious vomiting and a radiological evidence of postbulbar obstruction...
June 2017: Indian Journal of Surgery
Wenhong Liu, Jincai Liu, Wenlian Xiao, Guanghua Luo
RATIONALE AND OBJECTIVES: This study aimed to evaluate the diagnostic accuracy of magnetic resonance imaging (MRI) and computed tomography (CT) in assessing small bowel (SB) Crohn disease (CD). MATERIALS AND METHODS: We systematically searched PubMed, Elsevier, ScienceDirect, Karger, Web of Science, Wiley Online Library, and Springer for studies in which CT or MRI were evaluated to assess SB CD. Bivariate random effect meta-analytic methods were used to estimate pooled sensitivity, specificity, and receiver operating characteristic curves...
June 5, 2017: Academic Radiology
Heather I Gale, Steven M Sharatz, Mayureewan Taphey, William F Bradley, Katherine Nimkin, Michael S Gee
BACKGROUND: Assessment for active Crohn disease by CT enterography and MR enterography relies on identifying mural and perienteric imaging features. OBJECTIVE: To evaluate the performance of established imaging features of active Crohn disease in children and adolescents on CT and MR enterography compared with histological reference. MATERIALS AND METHODS: We included patients ages 18 years and younger who underwent either CT or MR enterography from 2007 to 2014 and had endoscopic biopsy within 28 days of imaging...
May 3, 2017: Pediatric Radiology
Timothy L Tsai, Megan B Marine, Matthew R Wanner, Matthew L Cooper, Steven J Steiner, Fangqian Ouyang, S Gregory Jennings, Boaz Karmazyn
BACKGROUND: There is growing literature on the use of ultrasound (US) for evaluation of Crohn disease in adults, but few studies have been conducted on children. Several studies demonstrated high accuracy of US in the diagnosis of Crohn disease. Using US as the primary screening imaging modality for Crohn disease can reduce health care costs, the need for sedation and ionizing radiation exposure. OBJECTIVE: The aim of our study is to determine if US can be used for screening evaluation of pediatric Crohn disease...
July 2017: Pediatric Radiology
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