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Multiple intraluminal impedance

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https://www.readbyqxmd.com/read/27602496/heparins-that-block-vegf-a-mediated-von-willebrand-factor-fiber-generation-are-potent-inhibitors-of-hematogenous-but-not-lymphatic-metastasis
#1
Lukas Goertz, Stefan Werner Schneider, Anna Desch, Frank Thomas Mayer, Julian Koett, Kai Nowak, Ioannis Karampinis, Michael K Bohlmann, Viktor Umansky, Alexander Thomas Bauer
Von Willebrand factor (VWF) serves as a nidus for platelet aggregation and thrombosis. We hypothesize that VWF fibers contribute to the development of venous thromboembolism (VTE) and to metastasis formation. Here, we show that vascular and lymphatic endothelial cells (ECs) express VWF in vitro and release VWF fibers after activation by tumor cell supernatants. In contrast, an ex vivo analysis of primary mouse tumors revealed the presence of VWF fibers in the blood microvasculature but not in lymphatic vessels...
September 2, 2016: Oncotarget
https://www.readbyqxmd.com/read/26958902/variability-in-the-cross-sectional-area-and-narrowing-of-the-internal-jugular-vein-in-patients-without-multiple-sclerosis
#2
Karen Buch, Raymond Groller, Rohini N Nadgir, Akifumi Fujita, Muhammad M Qureshi, Osamu Sakai
OBJECTIVE: Chronic cerebrospinal vascular insufficiency is a proposed condition of intraluminal stenosis of the internal jugular vein (IJV) that impedes venous flow from the brain. Calculations of IJV stenosis are vague and described in veins with at least a 50% reduction in IJV caliber at a specific level. The purpose of this study was to assess normal changes in anatomic caliber of the course of the IJV in a generalized population. MATERIALS AND METHODS: Images from 500 consecutive contrast-enhanced neck CT studies performed in January-July 2011 were reviewed...
May 2016: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/26554410/diagnosis-and-treatment-of-gastroesophageal-reflux-in-infants-and-children
#3
Drew C Baird, Dausen J Harker, Aaron S Karmes
Gastroesophageal reflux is defined as the passage of stomach contents into the esophagus with or without accompanied regurgitation (spitting up) and vomiting. It is a normal physiologic process that occurs throughout the day in infants and less often in children and adolescents. Gastroesophageal reflux disease (GERD) is reflux that causes troublesome symptoms or leads to medical complications. The diagnoses of gastroesophageal reflux and GERD are based on the history and physical examination. Diagnostic tests, such as endoscopy, barium study, multiple intraluminal impedance, and pH monitoring, are reserved for when there are atypical symptoms, warning signs, doubts about the diagnosis, or suspected complications or treatment failure...
October 15, 2015: American Family Physician
https://www.readbyqxmd.com/read/25345864/low-mean-impedance-in-24-hour-tracings-and-esophagitis-in-children-a-strong-connection
#4
S Salvatore, A Salvatoni, D Ummarino, A Ghanma, R Van der Pol, A Rongen, M Fuoti, F Meneghin, M Alexander Benninga, Y Vandenplas
Esophageal multiple intraluminal impedance baseline is an additional impedance parameter that was recently related to esophageal integrity. The aim of this study was to assess the relationship between mean esophageal impedance value and endoscopic findings in a large group of children. Children with symptoms of gastroesophageal reflux submitted to both endoscopy and impedance were included. Esophagitis was graded according to the Los Angeles classification. Mean impedance value was automatically calculated over 24-hour tracings...
January 2016: Diseases of the Esophagus: Official Journal of the International Society for Diseases of the Esophagus
https://www.readbyqxmd.com/read/24865809/pilot-study-association-between-helicobacter-pylori-in-adenoid-hyperplasia-and-reflux-episodes-detected-by-multiple-intraluminal-impedance-in-children
#5
R Katra, Z Kabelka, M Jurovcik, O Hradsky, J Kraus, E Pavlik, E Nartova, P Lukes, J Astl
OBJECTIVES: The aim of this pilot study was to investigate an association between laryngopharyngeal reflux detected by combined multiple intraluminal impedance and pH monitoring and Helicobacter pylori in adenoid hyperplasia detected with real time polymerase chain reaction (PCR). METHODS: The study group consisted of 30 children (median age 5.34 years) with extraesophageal symptoms of gastroesophageal reflux disease with adenoid hyperplasia. All children underwent adenoidectomy with subsequent PCR detection of H...
August 2014: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/24861157/esophageal-distension-during-bolus-transport-can-it-be-detected-by-intraluminal-impedance-recordings
#6
J H Kim, R K Mittal, N Patel, M Ledgerwood, V Bhargava
BACKGROUND: Esophageal multiple intraluminal impedance (MII) measurement has been used to detect gastro-esophageal reflux and bolus transport. It is not clear if MII can detect changes in luminal cross sectional area (CSA) during bolus transport. Intraluminal ultrasound (US) images, MII, and high resolution manometry (HRM) were recorded simultaneously to determine temporal relationship between CSA and impedance during esophageal bolus transport and to define the relationship between peak distension and nadir impedance...
August 2014: Neurogastroenterology and Motility: the Official Journal of the European Gastrointestinal Motility Society
https://www.readbyqxmd.com/read/24491501/lpr-how-different-diagnostic-tools-shape-the-outcomes-of-treatment
#7
COMPARATIVE STUDY
Yichen Wan, Yan Yan, Furong Ma, Li Wang, Peiquan Lu, Allison Maytag, Jack J Jiang
OBJECTIVE: To seek a deeper and more comprehensive understanding of two major diagnostic methods for laryngopharyngeal reflux by exploring whether and how differences exist before and after treatment between patients diagnosed by either Reflux Symptom Index (RSI) and Reflux Finding Score (RFS) or 24-hour pH monitoring. MATERIALS AND METHODS: Two groups of patients who confirmed laryngopharyngeal reflux disease (LPRD) by either a combination of RSI and RFS (Questionnaire group, 35 patients) or 24-hour multichannel intraluminal impedance (MII) pH monitoring (pH Group, 23 patients) were recruited...
May 2014: Journal of Voice: Official Journal of the Voice Foundation
https://www.readbyqxmd.com/read/23809340/neonatal-apnea-and-gastroesophageal-reflux-ger-is-there-a-problem
#8
REVIEW
Elie G Abu Jawdeh, Richard J Martin
Apnea of prematurity and gastroesophageal reflux (GER) are both common occurrences in preterm infants and widely perceived to be causally related. We seek in this review to provide a potential guideline for neonatal GER non-pharmacologic and pharmacologic therapy. Available physiologic data suggest that when there is a temporal relationship apnea may be more likely to predispose to GER via esophageal sphincter relaxation than vice versa. Measurement of multiple intraluminal impedance via esophageal catheter in addition to esophageal pH has enhanced our understanding of GER, although it also did not demonstrate a causal relationship between apnea and GER...
June 2013: Early Human Development
https://www.readbyqxmd.com/read/23698024/esophageal-impedance-baseline-is-age-dependent
#9
Silvia Salvatore, Alessandro Salvatoni, Marieke Van Berkel, Kristel Van Steen, Dario Unmarino, Abdallah Ghanma, Bruno Hauser, Yvan Vandenplas
OBJECTIVE: Esophageal impedance (multichannel intraluminal impedance [MII]) baseline (impedance baseline [IB]) has been recently considered to be related to esophageal integrity. The aim of this study was to analyze the age effect on IB in a large population of pediatric patients. DESIGN: A total of 816 children with symptoms of gastroesophageal reflux and submitted to MII were included. Mean IB was automatically calculated in the different MII channels (Chs) throughout 24-hour tracings by the specific software without removing any episode of increased/decreased IB...
October 2013: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/23581607/challenges-in-the-diagnosis-of-gastroesophageal-reflux-disease-in-infants-and-children
#10
REVIEW
Yvan Vandenplas
INTRODUCTION: The diagnosis of gastroesophageal reflux disease (GERD) is challenging. The wide variation in symptoms is a major reason for the controversies. Since the expression of GERD varies from nonerosive reflux disease over Barrett's esophagus to chronic respiratory disease, it is clear that not one investigation technique will provide an answer in all situations. AREAS COVERED: Relevant literature published in PubMed and CINAHL and recent guidelines were collected and reviewed...
May 2013: Expert Opinion on Medical Diagnostics
https://www.readbyqxmd.com/read/23576546/mutation-of-simple-in-charcot-marie-tooth-1c-alters-production-of-exosomes
#11
Hong Zhu, Sara Guariglia, Raymond Y L Yu, Wenjing Li, Deborah Brancho, Hector Peinado, David Lyden, James Salzer, Craig Bennett, Chi-Wing Chow
Charcot-Marie-Tooth (CMT) disease is an inherited neurological disorder. Mutations in the small integral membrane protein of the lysosome/late endosome (SIMPLE) account for the rare autosomal-dominant demyelination in CMT1C patients. Understanding the molecular basis of CMT1C pathogenesis is impeded, in part, by perplexity about the role of SIMPLE, which is expressed in multiple cell types. Here we show that SIMPLE resides within the intraluminal vesicles of multivesicular bodies (MVBs) and inside exosomes, which are nanovesicles secreted extracellularly...
June 2013: Molecular Biology of the Cell
https://www.readbyqxmd.com/read/23535760/absence-of-effect-of-nasal-continuous-positive-airway-pressure-on-the-esophageal-phase-of-nutritive-swallowing-in-newborn-lambs
#12
Djamal Djeddi, Danny Cantin, Nathalie Samson, Hao Tian, Jean-Paul Praud
OBJECTIVES: It is presently recommended that oral feeding be started in premature infants as soon as possible, often at an age at which nasal continuous positive airway pressure (nCPAP) is still required for ventilatory support. Our previous data showed that application of nCPAP up to 10 cmH2O in full-term lambs had no deleterious effect on cardiorespiratory safety, feeding efficiency, or on nutritive swallowing-breathing coordination. Besides fear of swallowing-breathing coordination disturbances, esophageal motility disruption by nCPAP could be a reason to delay oral feeding...
August 2013: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/23021166/subjective-and-objective-data-on-esophageal-manometry-and-impedance-ph-monitoring-1-year-after-endoscopic-full-thickness-plication-for-the-treatment-of-gerd-by-using-multiple-plication-implants
#13
Oliver O Koch, Adolf Kaindlstorfer, Stavros A Antoniou, Georg Spaun, Rudolph Pointner, Lee L Swanstrom
BACKGROUND: Subjective and especially objective data after endoluminal full-thickness gastroplication are scarce. OBJECTIVE: To evaluate symptoms and reflux activity 12 months after gastroplication by using multichannel intraluminal impedance monitoring. DESIGN: Open-label, prospective, single-center study. SETTING: Tertiary referral hospital in Zell am See, Austria. PATIENTS: Subjects without hiatal hernias with documented GERD and persistent or recurrent symptoms despite treatment with a proton pump inhibitor...
January 2013: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/22519455/gastroesophageal-and-laryngopharyngeal-reflux-profiles-in-patients-with-obstructive-sleep-apnea-hypopnea-syndrome-as-determined-by-combined-multichannel-intraluminal-impedance-ph-monitoring
#14
Y-L Xiao, F-Q Liu, J Li, J-T Lv, J-K Lin, W-P Wen, M-H Chen
BACKGROUND: The profiles of gastroesophageal reflux (GER) and laryngopharyngeal reflux (LPR) in patients with obstructive sleep apnea/hypopnea syndrome (OSAHS) have never been explored. The aim of the study was to investigate the reflux profile in OSAHS patients. METHODS: Consecutive snoring out-patients suspected with having OSAHS and 20 healthy volunteers were included. All subjects underwent simultaneous 24-h combined multichannel intraluminal impedance-pH (MII-pH) monitoring and polysomnography...
June 2012: Neurogastroenterology and Motility: the Official Journal of the European Gastrointestinal Motility Society
https://www.readbyqxmd.com/read/22415199/microalterations-of-esophagus-in-patients-with-non-erosive-reflux-disease-in-vivo-diagnosis-by-confocal-laser-endomicroscopy-and-its-relationship-with-gastroesophageal-reflux
#15
COMPARATIVE STUDY
Chuan-Lian Chu, Yan-Bo Zhen, Guo-Ping Lv, Chang-Qing Li, Zhen Li, Qing-Qing Qi, Xiao-Meng Gu, Tao Yu, Ting-Guo Zhang, Cheng-Jun Zhou, Rui-Ji, Yan-Qing Li
OBJECTIVES: Objectively diagnosing non-erosive reflux disease (NERD) is still a challenge. We aimed to evaluate the use of in-vivo confocal laser endomicroscopy (CLE) to examine the microalterations of the esophagus in patients with NERD and its relationship with reflux episodes monitored by multiple intraluminal impedance-pH (MII-pH). METHODS: Patients with gastroesophageal reflux symptoms completed reflux disease questionnaires. NERD was determined by negative gastroscopy...
June 2012: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/22373519/intraluminal-ultrasonic-probe-for-volumetric-monitoring-of-liquid-gastroesophageal-reflux
#16
X Gao, D C Sadowski, M P Mintchev
Methods for volumetric monitoring of liquid gastroesophageal reflux (GER) are still lacking. The aim of this study was to develop an automated intraluminal measurement technique which allows ambulatory volumetric quantification of liquid GER utilizing a minimum-cost intraluminal ultrasonic probe. This probe consists of two 2 MHz ultrasonic crystals longitudinally assembled along a multi-channel intraluminal impedance (MII) catheter. The proposed probe was initially tested with tubular phantoms of different diameters...
March 2012: Physiological Measurement
https://www.readbyqxmd.com/read/22340375/discrepancy-between-presumptive-and-definite-causes-of-chronic-cough
#17
Li Yu, Zhi-Hong Qiu, Wei-Li Wei, Bo Liu, Xiang-Huai Xu, Han-Jing Lü, Zhong-Min Qiu
BACKGROUND: The current diagnostic algorithms for chronic cough require the establishment of the primary presumptive causes followed by the confirmation of diagnosis with the specific therapies. The aim of the study was to investigate the discrepancy between presumptive and definite causes and its clinical implication. METHODS: A total of 109 patients with chronic cough underwent laboratory investigations to identify the cause of cough; including sinus computerized tomography (if needed), histamine bronchial provocation, induced sputum cytology and 24-hour esophageal pH or multi-channel intraluminal impedance combined with pH monitoring...
December 2011: Chinese Medical Journal
https://www.readbyqxmd.com/read/21865970/inter-and-intraobserver-agreement-in-24-hour-combined-multiple-intraluminal-impedance-and-ph-measurement-in-children
#18
MULTICENTER STUDY
Denisa Pilic, Carolin Höfs, Sandra Weitmann, Frank Nöh, Thorsten Fröhlich, Heino Skopnik, Henrik Köhler, Tobias G Wenzl, Anjona Schmidt-Choudhury
OBJECTIVES: Assessment of intra- and interobserver agreement in multiple intraluminal impedance (MII) measurement between investigators from different institutions. METHODS: Twenty-four 18- to 24-hour MII tracings were randomly chosen from 4 different institutions (6 per center). Software-aided automatic analysis was performed. Each result was validated by 2 independent investigators from the 4 different centers (4 investigator combinations). For intraobserver agreement, 6 measurements were analyzed twice by the same investigator...
September 2011: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/21752021/does-multiple-intraluminal-impedance-monitoring-have-a-role-in-evaluating-children-with-neurological-impairment-before-percutaneous-endoscopic-gastrostomy
#19
COMMENT
John Fortunato
No abstract text is available yet for this article.
October 2011: Developmental Medicine and Child Neurology
https://www.readbyqxmd.com/read/21752017/influence-of-percutaneous-endoscopic-gastrostomy-on-gastro-oesophageal-reflux-evaluated-by-multiple-intraluminal-impedance-in-children-with-neurological-impairment
#20
Ewa Toporowska-Kowalska, Beata Gębora-Kowalska, Janusz Jabłoński, Wojciech Fendler, Krystyna Wąsowska-Królikowska
AIM: The aim of the study was to estimate the influence of percutaneous endoscopic gastrostomy (PEG) placement on gastro-oesophageal reflux (GOR) by using multiple intraluminal impedance (MII/pH) measurements in children with neurological impairments. METHOD: Fifteen children with neurological impairments (cerebral palsy, n=10; cerebroidolipofuscinosis, n=2; Aicardi syndrome, n=1; and secondary encephalopathy, n=2) were investigated (interquartile range [IQR] 6y 4mo-14y 8mo; median age 10y 2mo; eight male, seven female)...
October 2011: Developmental Medicine and Child Neurology
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