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spondylodiscitis

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https://www.readbyqxmd.com/read/28639530/mortality-and-health-related-quality-of-life-in-patients-surgically-treated-for-spondylodiscitis
#1
Casper Dragsted, Theis Aagaard, Søren Ohrt-Nissen, Martin Gehrchen, Benny Dahl
PURPOSE: To assess mortality, disability, and health-related quality of life (HRQL) in patients surgically treated for spondylodiscitis. METHODS: A retrospective longitudinal study was conducted on all patients surgically treated for spondylodiscitis over a 6-year period at a single tertiary spine center. Indications for surgery, pre- and postoperative neurological impairment, comorbidities, and mortality were recorded. A survey was conducted on all eligible patients with the EuroQol 5-dimension (EQ-5D) questionnaire and Oswestry Disability Index (ODI)...
May 2017: Journal of Orthopaedic Surgery
https://www.readbyqxmd.com/read/28608178/minimally-invasive-spine-surgery-in-lumbar-spondylodiscitis-a-retrospective-single-center-analysis-of-67-cases
#2
Anja Tschugg, Sebastian Hartmann, Sara Lener, Andreas Rietzler, Neururer Sabrina, Claudius Thomé
BACKGROUND: Minimally invasive surgical techniques have been developed to minimize tissue damage, reduce narcotic requirements, decrease blood loss, and, therefore, potentially avoid prolonged immobilization. Thus, the purpose of the present retrospective study was to assess the safety and efficacy of a minimally invasive posterior approach with transforaminal lumbar interbody debridement and fusion plus pedicle screw fixation in lumbar spondylodiscitis in comparison to an open surgical approach...
June 12, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28602673/typhoid-spondylodiscitis-mimicking-tuberculosis-in-a-teenage-girl
#3
Barnini Banerjee, Mridula Madiyal, Pai K Madhava, Manali Agarwal, Chiranjay Mukhopadhyay
Salmonella Typhi cause a broad spectrum of human illnesses like gastroenteritis, typhoid fever, and bacteremia. It has also been recognized as a causative organism of osteomyelitis for more than a century but the incidence appears to be uncommon. Microbiological workup plays important role in the diagnosis of Typhoid spondylodiscitis as most of the time it mimics tuberculosis and misguide the clinician, especially in the developing world. Here, we reported an uncommon case of lumbar spondylodiscitis by Salmonella Typhi in an immunocompetent teenager, with the help of clinical, microbiological and radiological evidence...
June 8, 2017: Journal of Infection and Public Health
https://www.readbyqxmd.com/read/28593383/tubercular-spondylodiscitis-in-elderly-is-a-more-severe-disease-a-report-of-66-consecutive-patients
#4
Ajoy Prasad Shetty, Vibhu Krishnan Viswanathan, Rishi Mukesh Kanna, Rajasekaran Shanmuganathan
PURPOSE: (1) To analyze peculiarities of presentation and prognosis of tubercular spondylodiscitis (TBS) in elderly. (2) To assess if associated co-morbidities and risks lead to poorer outcome (3) To observe if different management strategy needs to be implemented in them. METHODS: Retrospective analysis of 66 consecutive elderly TBS patients (>60 years) treated conservatively or surgically between January 2010 and July 2013 was performed. Details regarding clinical presentation (general health, ambulatory status, co-morbidities), neurological status, medical or surgical complications and outcome measurements [visual analog score, clinico-radiological evidence of healing and lumbar lordosis in lumbar (L) or lumbo-sacral (LS) or focal kyphosis in thoracic (T) or thoraco-lumbar (TL) disease] were analysed...
June 7, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28589391/-spondylodiscitis-current-strategies-for-diagnosis-and-treatment
#5
I Michiels, M Jäger
Spondylodiscitis is a severe infectious disease of the intervertebral discs and of the adjacent parts of the vertebral bodies, culminating in destruction of the mobile segment. It is accompanied by a mortality rate of approximately 15%. Severe courses of the disease can also lead to abscess formation and dispersal of sepsis. Malpositioning of the axis organ and deficits in neurological function up to paraplegia are also possible complications. Timely diagnostics and targeted therapy contribute to minimizing the risk of significant health disorders...
June 6, 2017: Der Orthopäde
https://www.readbyqxmd.com/read/28583099/magnetic-resonance-imaging-of-bacterial-and-tuberculous-spondylodiscitis-with-associated-complications-and-non-infectious-spinal-pathology-mimicking-infections-a-pictorial-review
#6
REVIEW
Yogesh Kumar, Nishant Gupta, Avneesh Chhabra, Takeshi Fukuda, Neetu Soni, Daichi Hayashi
Magnetic resonance (MR) imaging plays an important role in the evaluation of bacterial and tuberculous spondylodiscitis and associated complications. Owing to its high sensitivity and specificity, it is a powerful diagnostic tool in the early diagnosis of ongoing infections, and thus provides help in prompt initiation of appropriate, therapy which may be medical or surgical, by defining the extent of involvement and detection of complications such as epidural and paraspinal abscesses. More specifically, MR imaging helps in differentiating bacterial from tuberculous infections and enables follow up of progression or resolution after appropriate treatment...
June 5, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28569143/spondylodiscitis-in-a-healthy-12-year-old-girl-with-extraintestinal-pathogenic-escherichia-coli-expec-bacteraemia
#7
J Gaschignard, G Geslain, C Mallet, M Lorrot, N Blot, M Alison, S Bonacorsi
BACKGROUND: Escherichia coli (E. coli) is rarely implicated in bone or joint infections in children. CASE PRESENTATION: We discuss the case of a healthy 12-year-old girl with an E. coli bacteraemia and a T11-T12 spondylodiscitis revealed by magnetic resonance imaging. The strain harboured serogroup O1:K1 and virulence factors common to highly virulent extra intestinal pathogenic E. coli (ExPEC). Immunological work-up was normal. CONCLUSION: The identification of E...
May 31, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28559082/computed-tomography-and-magnetic-resonance-imaging-parameters-associated-with-poor-clinical-outcome-in-spondylodiscitis
#8
Sarah C Foreman, Benedikt J Schwaiger, Bernhard Meyer, Alexandra S Gersing, Claus Zimmer, Jens Gempt, Jan S Kirschke
BACKGROUND: Prognostic factors for the disease course of patients with spondylodiscitis have not yet been well studied. METHODS: The prognostic value of initial MR and CT imaging parameters was analyzed in 62 patients (47% women; mean age ± SD, 71.6 years ± 9.6) with a confirmed diagnosis of spondylodiscitis. The disease course was separately evaluated during initial treatment response whilst hospitalized, relapse, and clinical short-term follow-up at three months...
May 27, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28544837/candida-endocarditis-a-review-of-twelve-episodes-in-eleven-patients
#9
Tatjana Lejko Zupanc, Mateja Logar
BACKGROUND: Candida spp. are a rare but important cause of infective endocarditis. The study aim was to describe pertinent clinical data on consecutive patients with Candida endocarditis treated at a tertiary referral center between 1984 and 2013. METHODS: A retrospective search of the authors' endocarditis database was performed and the medical records of patients with confirmed Candida endocarditis were reviewed. Important data relating to demographics, medical history and clinical data, as well as information on outcome and treatment, were extracted...
January 2017: Journal of Heart Valve Disease
https://www.readbyqxmd.com/read/28538361/characteristics-of-and-risk-factors-for-severe-neurological-deficit-in-patients-with-pyogenic-vertebral-osteomyelitis-a-case-control-study
#10
Adrien Lemaignen, Idir Ghout, Aurélien Dinh, Guillaume Gras, Bruno Fantin, Virginie Zarrouk, Robert Carlier, Jean-Edouard Loret, Eric Denes, Alix Greder, François-Xavier Lescure, David Boutoille, Pierre Tattevin, Bertrand Issartel, Jean-Philippe Cottier, Louis Bernard
Severe neurological deficit (SND) is a rare but major complication of pyogenic vertebral osteomyelitis (PVO). We aimed to determine the risk factors and the variables associated with clinical improvement for SND during PVO.This case-control study included patients without PVO-associated SND enrolled in a prospective randomized antibiotic duration study, and patients with PVO-associated SND managed in 8 French referral centers. Risk factors for SND were determined by logistic regression.Ninety-seven patients with PVO-associated SND cases, and 297 controls were included...
May 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28537686/the-effectiveness-of-computed-tomography-guided-biopsy-for-the-diagnosis-of-spondylodiscitis-an-analysis-of-variables-affecting-the-outcome
#11
N Ahuja, H Sharma
OBJECTIVE: To analyze: (i) the effectiveness of CT-guided biopsy for the diagnosis of suspected spinal infections (spondylodiscitis); (ii) identify common causative microorganisms and assess factors that could affect the diagnostic yield. PATIENTS AND METHODS: Forty-five patients undergoing CT-guided biopsy for suspected spinal infection between November 2012 and October 2014 were analyzed. The time from presentation to diagnosis, administration of antibiotics before biopsy, blood culture results, admission C-reactive protein (CRP)/white cell count, presence of fever or neurological deficits, and soft tissue collections on MRI were analyzed...
May 2017: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/28512590/acute-bacterial-meningitis-and-systemic-abscesses-due-to-streptococcus-dysgalactiae-subsp-equisimilis-infection
#12
M Jourani, T Duprez, V Roelants, H Rodriguez-Villalobos, P Hantson
Disseminated abscesses due to group G β-hemolytic Streptococcus dysgalactiae were observed in a 57-year-old cirrhotic patient with the skin being the putative way of entry for the pathogen. S. dysgalactiae is a rare agent in human infections responsible for acute pyogenic meningitis. The mortality rate associated with S. dysgalactiae bacteraemia and meningitis may be as high as 50%, particularly in the presence of endocarditis or brain abscesses. In our patient, main sites of infections were meningitis and ventriculitis, spondylodiscitis, septic arthritis, and soft-tissue infections...
2017: Case Reports in Infectious Diseases
https://www.readbyqxmd.com/read/28507893/delayed-diagnosis-of-severe-tuberculous-spondylodiscitis-in-an-asylum-seeker-patient-or-doctors-delay
#13
Kristina Langholz Kristensen, Daria Podlekareva, Pernille Ravn
The still increasing global migration affects the epidemiology of tuberculosis (TB) in European countries. We present the case of an asylum seeker from a TB high-endemic country, who presented with severe TB spondylodiscitis and need for emergency surgery. The patient had a history of recurrent sterile axillary and perianal abscesses for years, but TB was never properly ruled out. The patient underwent surgery, responded well to antibiotics and regained the ability to walk. After 6 month of treatment the patient was lost to follow-up...
2017: Respiratory Medicine Case Reports
https://www.readbyqxmd.com/read/28495228/post-operative-spondylodiscitis-due-to-propionibacterium-acnes-a-case-report
#14
R André, N Sabeh
Post-operative spondylodiscitis due to Propionibacterium acnes is rare, with only a few cases reported in the literature. In this article, we report the case of a 76-year-old patient who suffered from spondylodiscitis T12-L1 discovered after 1 month of pain and fever. Antibiotic treatment was administered for 6 weeks without revision surgery. Diagnosis remains incomplete, and preventive therapy against this infection is not well known. There is no link between immunosuppression and this infection. A cure has been reported in 98% of cases, but further investigation is still required for the establishment of treatment guidelines...
May 8, 2017: Neuro-Chirurgie
https://www.readbyqxmd.com/read/28484299/radiologic-diagnosis-of-spondylodiscitis-role-of-magnetic-resonance
#15
Naser Ramadani, Kreshnike Dedushi, Serbeze Kabashi, Sefedin Mucaj
INTRODUCTION: Study aim is to report the Magnetic Resonance Imaging (MRI) features of acute and chronic spontaneous spondylodiscitis. CASE REPORT: 57 year old female, complaining of a fever and longstanding cervical pain worsened during physical therapy. METHODS: MR images were acquired using superconductive magnet 1.5 T, with the following sequences: sagittal PD and T2 TSE, sagittal T1 SE, axial PD and T2 TSE (lumbar spine), axial T2 GRE (cervical spine)...
March 2017: Acta Informatica Medica: AIM
https://www.readbyqxmd.com/read/28481045/pre-and-postoperative-magnetic-resonance-imaging-mri-findings-in-patients-treated-with-laparoscopic-sacrocolpopexy-is-it-a-safe-procedure-for-all-patients
#16
Dimitrios Zacharakis, Themos Grigoriadis, Charis Bourgioti, Eleni Pitsouni, Athanasios Protopapas, Lia A Moulopoulos, Stavros Athanasiou
INTRODUCTION: Laparoscopic sacrocolpopexy (LSCP) is a reference operation for apical compartment prolapse repair. Aim of this study is to describe the early and midterm postoperative MRI findings of the lumbosacral region (LSR) in patients undergoing LSCP and to detect any imaging changes that the presence of the mesh may cause on patients with preexisting degenerative disease of the LSR. METHODS: Patients with POP-Q grade III and IV uterovaginal or vaginal vault prolapse who were considered eligible for LSCP were invited to participate...
May 8, 2017: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/28477437/national-epidemiological-study-reveals-longer-paediatric-bone-and-joint-infection-stays-for-infants-and-in-general-hospitals
#17
E Laurent, L Petit, Z Maakaroun-Vermesse, L Bernard, T Odent, L Grammatico-Guillon
AIM: Published studies have suggested that 2-5 days of intravenous treatment could effectively treat paediatric bone and joint infections (PBJI), allowing a faster discharge. This study analysed the factors associated with PBJI hospital stays lasting longer than five days using the French National Hospital Discharge Database. METHODS: We selected children under 15 years hospitalised in 2013 with haematogenous PBJIs using a validated French algorithm based on specific diagnosis and surgical procedure codes...
May 6, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/28457929/cervical-spondylodiscitis-presentation-timing-and-surgical-management-in-59-patients
#18
George M Ghobrial, Daniel Franco, Thana Theofanis, Philip J Margiotta, Edward Andrews, Jefferson Wilson, James S Harrop, Joshua E Heller
BACKGROUND: Cervical spondylodiscitis is thought to carry a significant risk for rapid neurologic deterioration with a poor response to nonsurgical management. METHODS: A retrospective surgical case series of the acute surgical management of cervical spondylodiscitis is reviewed to characterize the neurologic presentation and postoperative neurologic course in a relatively uncommon disease. RESULTS: 59 patients were identified (mean age 59 yrs, range 18-83yrs, SD ±13...
April 27, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28449655/early-surgery-with-antibiotics-treatment-had-better-clinical-outcomes-than-antibiotics-treatment-alone-in-patients-with-pyogenic-spondylodiscitis-a-retrospective-cohort-study
#19
Tsung-Ting Tsai, Shih-Chieh Yang, Chi-Chien Niu, Po-Liang Lai, Ming-Hsun Lee, Lih-Huei Chen, Wen-Jer Chen
BACKGROUND: Pyogenic spondylodiscitis is a form of spinal infection that can result in severe back pain and even death. However, information is lacking on the relative effectiveness of various therapies. A retrospective chart review was conducted to investigate whether early surgical treatment of pyogenic spondylodiscitis coupled with intravenous antibiotics results in better patient prognoses than intravenous antibiotics therapy alone. METHODS: All patients treated for pyogenic spondylodiscitis at a single medical center from July 2006 to July 2011 were retrospectively reviewed...
April 27, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28414168/decompression-alone-versus-fusion-for-pyogenic-spondylodiscitis
#20
Sung Hyun Noh, Ho Yeol Zhang, Hyun Sun Lim, Hyeon Jin Song, Kyung Hwa Yang
BACKGROUND CONTEXT: A spinal infection is a serious problem for a spine surgeon, and there is currently much debate regarding how best to treat pyogenic spondylodiscitis using antibiotics and the instrumentations that have been developed to date. PURPOSE: The purpose of this study was to determine which is better method for treating pyogenic spondylodiscitis. STUDY DESIGN/SETTING: A retrospective chart review was performed. PATIENT SAMPLE: Thirty-one patients with pyogenic spondylodiscitis underwent surgical treatment between 2000 and 2016 at the authors' institution...
April 13, 2017: Spine Journal: Official Journal of the North American Spine Society
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