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nitrous oxide anesthesia

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https://www.readbyqxmd.com/read/29043904/effects-of-anesthesia-with-nitrous-oxide-on-tympanoplasty-outcomes-a-randomized-controlled-trial
#1
Ali Kouhi, Fatemeh Hajimohammadi, Sasan Dabiri, Amin Amali, Neda Enayati, Sahar Manavi, Niloufar Saeedi, Ziba Bidar
OBJECTIVES: To investigate effects of nitrous oxide (N2O), as inhalational anesthetic agent, on tympanoplasty outcomes. METHODS: In this randomized controlled trial, patients were randomized into two groups: 39 patients who received N2O as an inhalant anesthesia and 47 patients who did not receive. All were operated on with standard type of ear surgery. The protocol for the two groups was identical. Before surgery baseline audiometry was performed. Postoperative audiological controls were carried out at 3 months...
October 18, 2017: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/28890309/pupillary-response-to-nitrous-oxide-administration-in-cataract-surgery-under-general-anesthesia
#2
Mansoor Masjedi, Alireza Ghanbari, Hossein Haddad Bakhodaei, Tahere Jowkar, Vahhab Hosseni, Mahnaz Rakhshan
BACKGROUND: Despite recent innovations in cataract surgery, pupillary diameter is one of the most important affecting factors in outcome of this surgery. As cataract surgery is performed ideally when the pupil is sufficiently dilated, anesthesia may contribute significantly in success or failure of this operation. This study was performed to evaluate the effect of nitrous oxide on pupillary diameter in cataract surgery under general anesthesia. METHODS: Forty patients with cataract, scheduled for operation under general anesthesia, were randomly allocated into two groups...
September 7, 2017: Journal of the Chinese Medical Association: JCMA
https://www.readbyqxmd.com/read/28877822/effect-of-intravenous-dexmedetomidine-injection-1-%C3%AE-g-kg-on-the-intubating-conditions-without-muscle-relaxants-in-children-after-inhalation-induction-with-sevoflurane
#3
Ling-Xin Wei, Xiao-Ming Deng, Lei Wang, Jing-Hu Sui, Juan Zhi, Chao Wen, Jin Xu, Ju-Hui Liu
Objective To investigate the effect of intravenous dexmedetomidine injection(1 μg/kg)on the intubating conditions after inhalation induction with sevoflurane 8% and nitrous oxide(N2O)50% in children. Methods Totally 122 patients aged 4-10 years with an American Society of Anesthesiologists physical statusⅠ undergoing elective plastic surgery under general anesthesia were randomly divided to dexmedetomidine group(intraveneously injected with dexmedetomidine 1μg/kg)and control group(injected with normal saline)by using the random sampling table...
August 20, 2017: Zhongguo Yi Xue Ke Xue Yuan Xue Bao. Acta Academiae Medicinae Sinicae
https://www.readbyqxmd.com/read/28858557/inner-wall-detachment-of-the-spiral-tube-during-extubation-a-case-report
#4
Tomo Morota, Katsuya Endou, Hiroshi Omizo, Setsuo Furuta, Hisashi Miyajima
We report a case of endotracheal tube malfunction, in which the inner surface of the tube peeled off during anesthesia. The patient, a 7-year-old boy, was under general anesthesia for the treatment of multiple dental caries. The damaged tube could have caused respiratory failure, putting the patient's life at risk. We speculate that the use of nitrous oxide was one of the contributing factors to the inner wall detachment. Several additional lessons can be learned from this incident in order to prevent tube-related trouble during an operation...
2017: Anesthesia Progress
https://www.readbyqxmd.com/read/28851284/anesthetic-management-of-a-pediatric-patient-with-electron-transfer-flavoprotein-dehydrogenase-deficiency-etfdh-and-acute-appendicitis-case-report-and-review-of-the-literature
#5
Emmanuel Lilitsis, Elisavet Astyrakaki, Evaggelos Blevrakis, Sofia Xenaki, George Chalkiadakis, Emmanuel Chrysos
BACKGROUND: Mitochondria are the energy producing organelles practically in every human cell except erythrocytes. Indeed mitochondria are widespread in high energy requiring organs like brain, heart and muscles. Currently there are no clinical trials supporting with clear evidence which is the most suitable surgical or anesthetic management of a patient with known mitochondrial disease presenting with surgical disorders. This condition poses possible hazardous problems to the medical attention of those patients...
August 29, 2017: BMC Anesthesiology
https://www.readbyqxmd.com/read/28840475/histone-deacetylase-inhibitor-entinostat-ms-275-restores-anesthesia-induced-alteration-of-inhibitory-synaptic-transmission-in-the-developing-rat-hippocampus
#6
Srdjan M Joksimovic, Hari Prasad Osuru, Azra Oklopcic, Mark P Beenhakker, Vesna Jevtovic-Todorovic, Slobodan M Todorovic
Recent evidence strongly supports the idea that common general anesthetics (GAs) such as isoflurane (Iso) and nitrous oxide (N2O; laughing gas), as well as sedative drugs such as midazolam are neurotoxic for the developing mammalian brain having deleterious effects on neural circuits involved in cognition, learning and memory. However, to date, very little is known about epigenetic mechanisms involved in GA-induced plasticity of synaptic transmission in the hippocampus, the main memory-processing region in the brain...
August 24, 2017: Molecular Neurobiology
https://www.readbyqxmd.com/read/28755978/duration-of-isoflurane-based-surgical-anesthesia-determines-severity-of-brain-injury-and-neurological-deficits-after-a-transient-focal-ischemia-in-young-adult-rats
#7
Nikhil Gaidhani, Fen Sun, Derek Schreihofer, Victor V Uteshev
Tremendous efforts and funds invested in discovery of novel drug treatments for ischemic stroke have so far failed to deliver clinically efficacious therapies. The reasons for these failures are not fully understood. An indiscriminate use of isoflurane-based surgical anesthesia with or without nitrous oxide may act as an unconstrained, untraceable source of data variability, potentially causing false-positive or false-negative results. To test this hypothesis, a common transient suture middle cerebral artery occlusion (tMCAO) model of ischemic stroke in young adult male rats was used to determine the impact of a typical range of anesthesia durations required for this model on data variability (i...
July 27, 2017: Brain Research Bulletin
https://www.readbyqxmd.com/read/28658119/is-neuromuscular-blocker-needed-in-children-undergoing-inguinal-herniorrhaphy-a-prospective-randomized-and-controlled-trial
#8
RANDOMIZED CONTROLLED TRIAL
Bon-Wook Koo, Kyu-Whan Jung, Ah-Young Oh, Eun-Young Kim, Hyo-Seok Na, Eun-Su Choi, Kwang-Suk Seo
BACKGROUND: Intraoperative neuromuscular blocker is widely used, but is known to be associated with postoperative residual paralysis, which is known to be associated with increased risk of pulmonary complications. Hence, its use should be individualized and restricted to procedures where it is mandatory. We examined whether not using a neuromuscular blocker affects the surgical conditions in children undergoing inguinal herniorrhaphy. METHODS: Anesthesia was induced and maintained with sevoflurane in 60% nitrous oxide, and the airway was maintained using an I-gel...
June 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28632629/evaluation-of-nitrous-oxide-in-the-gas-mixture-for-anesthesia-ii-enigma-ii-revisited-patients-still-vomiting
#9
Edmond C K Li, Lloyd D Balbuena, Jonathan J Gamble
No abstract text is available yet for this article.
July 2017: Anesthesiology
https://www.readbyqxmd.com/read/28597354/pharmacologic-considerations-for-pediatric-sedation-and-anesthesia-outside-the-operating-room-a-review-for-anesthesia-and-non-anesthesia-providers
#10
REVIEW
Narjeet Khurmi, Perene Patel, Molly Kraus, Terrence Trentman
Understanding the pharmacologic options for pediatric sedation outside the operating room will allow practitioners to formulate an ideal anesthetic plan, allaying anxiety and achieving optimal immobilization while ensuring rapid and efficient recovery. The authors identified relevant medical literature by searching PubMed, MEDLINE, Embase, Scopus, Web of Science, and Google Scholar databases for English language publications covering a period from 1984 to 2017. Search terms included pediatric anesthesia, pediatric sedation, non-operating room sedation, sedation safety, and pharmacology...
June 8, 2017: Paediatric Drugs
https://www.readbyqxmd.com/read/28554357/accuracy-of-children-s-perioperative-memories
#11
Thomas Hackmann, Rebecca A Haworth, Paul Hong, Joanne Gillespie, Jill Chorney
Children's declarative memories of medical procedures can influence their responses to subsequent events. No previous study has examined the accuracy of children's declarative memories after surgery. We tested the memory of 34 anesthesia-naïve five- to nine-year-old children undergoing ambulatory surgery for accuracy of contextual details, pain, and fear two weeks postoperatively. Parents were not present during induction, and we did not use sedative premedication. Children had a mean contextual recall accuracy of 64...
June 2017: AORN Journal
https://www.readbyqxmd.com/read/28448331/a-nurse-directed-model-for-nitrous-oxide-use-during-labor
#12
Toni Pinyan, Kelly Curlee, Mellanie Keever, Kathleen M Baldwin
BACKGROUND: Nitrous oxide has a long history of use and has been well documented in the literature as a safe, effective, and inexpensive option for pain management in labor in other countries, but it is underused in the United States. LOCAL PROBLEM: Pain relief options for laboring women in rural community hospitals with a small perinatal service are limited due to lack of availability of in-house anesthesia coverage. METHOD: This quality improvement project involved development and implementation of a nurse-driven, self-administered, demand-flow nitrous oxide program as an option for pain relief for laboring women in a rural community hospital...
May 2017: MCN. the American Journal of Maternal Child Nursing
https://www.readbyqxmd.com/read/28437304/nitrous-oxide-utility-in-labor-and-birth-a-multipurpose-modality
#13
Michelle Collins
The use of nitrous oxide (N2O) for labor and birth has very recently emerged as a viable modality in the United States, despite a long history of use in Canada and Europe. Usually associated with dental procedures, there are significant differences between dental and parturition utility, efficacy, and staff exposure. In addition to using it for pain relief and anxiolysis, those centers utilizing it have noted it to be multipurpose and useful for such situations as: external cephalic version, manual removal of placenta, intravenous starts, during placement of urinary catheters and intracervical Foley bulbs...
April 2017: Journal of Perinatal & Neonatal Nursing
https://www.readbyqxmd.com/read/28418969/funding-the-revival-of-nitrous-oxide-anesthesia-publisher-g-q-colton-issues-edward-everett-s-great-issues
#14
(no author information available yet)
No abstract text is available yet for this article.
May 2017: Anesthesiology
https://www.readbyqxmd.com/read/28372932/relationship-between-the-incidence-and-risk-factors-of-postoperative-nausea-and-vomiting-in-patients-with-intravenous-patient-controlled-analgesia
#15
Myung Sub Yi, Hyun Kang, Min Kyoung Kim, Geun-Joo Choi, Yong-Hee Park, Chong Wha Baek, Yong Hun Jung, Young Cheol Woo
OBJECTIVE: This study aims to evaluate retrospectively the electronic medical records of surgical patients who received intravenous patient-controlled analgesia, to identify potential relationships between the incidence and risk factors of postoperative nausea and vomiting (PONV). METHODS: Records of 6773 adult patients who received fentanyl-based intravenous patient-controlled analgesia after surgery at Chung-Ang University Hospital between January 1, 2010 and December 31, 2015 were reviewed...
March 31, 2017: Asian Journal of Surgery
https://www.readbyqxmd.com/read/28298780/effects-of-inhaled-nitrous-oxide-on-the-induction-dose-and-time-requirements-of-propofol-a-prospective-randomized-double-blind-study
#16
Kavita Jain, Surendra Kumar Sethi, Mamta Damor, Neena Jain
CONTEXT: Propofol is a commonly used induction agent during general anesthesia. As a sole agent, it does not provide any strong analgesic effect. The nitrous oxide (N2O) used along with propofol for induction of anesthesia augments the induction characteristics and reduces the dose of propofol. AIMS: To study the effects of inhaled N2O on the induction dose and time of propofol during general anesthesia and also its hemodynamic response and adverse effects. SETTINGS AND DESIGN: The present research is a prospective, randomized, double-blind comparative study...
January 2017: Anesthesia, Essays and Researches
https://www.readbyqxmd.com/read/28181932/evaluation-of-nitrous-oxide-in-the-gas-mixture-for-anesthesia-enigma-studies-the-tale-of-two-large-pragmatic-randomized-controlled-trials
#17
Girish P Joshi, John H Pennant, Henrik Kehlet
No abstract text is available yet for this article.
June 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/28178175/the-effect-of-nicardipine-on-the-surgical-pleth-index-during-thyroidectomy-under-general-anesthesia-a-prospective-double-blind-randomized-controlled-trial
#18
RANDOMIZED CONTROLLED TRIAL
Young Ju Won, Byung Gun Lim, Gwi Eun Yeo, Min Ki Lee, Dong Kyu Lee, Heezoo Kim, Il Ok Lee, Myoung Hoon Kong
BACKGROUND: The effectiveness of surgical pleth index (SPI) for managing nociception-antinociception balance during general anesthesia with vasodilators, including nicardipine has not been demonstrated. We aimed to compare the time course during surgery in SPI values in patients receiving nicardipine or remifentanil infusion during thyroidectomy. METHODS: Forty patients undergoing thyroidectomy were randomly assigned to receive nicardipine (group N; n = 19) or remifentanil (group R; n = 21) along with induction (propofol, fentanyl, and rocuronium) and maintenance (50% desflurane/nitrous oxide in oxygen) anesthesia (goal bispectral index [BIS] ∼50)...
February 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28122007/impact-of-stroke-therapy-academic-industry-roundtable-stair-guidelines-on-peri-anesthesia-care-for-rat-models-of-stroke-a-meta-analysis-comparing-the-years-2005-and-2015
#19
COMPARATIVE STUDY
Aurelie Thomas, Johann Detilleux, Paul Flecknell, Charlotte Sandersen
Numerous studies using rats in stroke models have failed to translate into successful clinical trials in humans. The Stroke Therapy Academic Industry Roundtable (STAIR) has produced guidelines on the rodent stroke model for preclinical trials in order to promote the successful translation of animal to human studies. These guidelines also underline the importance of anaesthetic and monitoring techniques. The aim of this literature review is to document whether anaesthesia protocols (i.e., choice of agents, mode of ventilation, physiological support and monitoring) have been amended since the publication of the STAIR guidelines in 2009...
2017: PloS One
https://www.readbyqxmd.com/read/28106353/causes-of-sore-throat-after-intubation-a-prospective-observational-study-of-multiple-anesthesia-variables
#20
Phillip D Levin, Chrysostomou Chrysostomos, Carlos A Ibarra, Stephan Ledot, Daigo Naito, Charles Weissman, Alexander Avidan
BACKGROUND: Sore throat is common after intubation for surgery. This observational study investigated cuff pressure and a large range of clinical covariates to explore the etiology of sore throat. METHODS: Approximately 24 hours after surgery six questions relating to pain, upper airway symptoms and sore throat were delivered to patients who had undergone intubation. Sore throat was correlated with demographics, anesthesia variables and cuff pressure (measured for a subset of patients)...
June 2017: Minerva Anestesiologica
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