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https://www.readbyqxmd.com/read/27924208/local-anesthesia-with-monitored-anesthesia-care-for-patients-undergoing-thyroidectomy-a-case-series
#1
Se Eun Kim, Eugene Kim
Because the current trend favors minimally invasive surgery for thyroid disease, increasing interest has developed for thyroidectomy under local anesthesia with monitored anesthesia care (MAC). Here, we retrospectively reviewed 18 cases of thyroidectomy performed under local anesthesia with MAC in a single center. All of the procedures were performed by a single surgeon, using local lidocaine infiltration around the incisional site and propofol plus remifentanil target-controlled infusion. Sore throat (4/18), hypocalcemia (1/18), and transient voice color change (1/18) were observed, but the patients recovered during the follow-up period...
December 2016: Korean Journal of Anesthesiology
https://www.readbyqxmd.com/read/27919589/preincisional-and-postoperative-epidural-morphine-ropivacaine-ketamine-and-naloxone-treatment-for-postoperative-pain-management-in-upper-abdominal-surgery
#2
Hou-Chuan Lai, Chung-Bao Hsieh, Chih-Shung Wong, Chun-Chang Yeh, Zhi-Fu Wu
OBJECTIVE(S): Previous studies have shown that preincisional epidural morphine, bupivacaine, and ketamine combined with epidural anesthesia (EA) and general anesthesia (GA) provided pre-emptive analgesia for upper abdominal surgery. Recent studies reported that ultralow-dose naloxone enhanced the antinociceptive effect of morphine in rats. This study investigated the benefits of preincisional and postoperative epidural morphine + ropivacaine + ketamine + naloxone (M + R + K + N) treatment for achieving postoperative pain relief in upper abdominal surgery...
December 2, 2016: Acta Anaesthesiologica Taiwanica: Official Journal of the Taiwan Society of Anesthesiologists
https://www.readbyqxmd.com/read/27896411/the-effects-of-intravenous-lidocaine-infusions-on-the-quality-of-recovery-and-chronic-pain-after-robotic-thyroidectomy-a-randomized-double-blinded-controlled-study
#3
Kwan Woong Choi, Kee-Hyun Nam, Jeong-Rim Lee, Woong Youn Chung, Sang-Wook Kang, Young Eun Joe, Jae Hoon Lee
BACKGROUND: The effect of the systemic lidocaine on postoperative recovery has not been definitively investigated despite its analgesic efficacy after surgery. The aim of this randomized, double-blinded, controlled study was to evaluate the effect of intravenously administered lidocaine on the quality of recovery and on acute and chronic postoperative pain after robot-assisted thyroidectomy. METHODS: Ninety patients who were undergoing robotic thyroidectomy were randomly assigned to the lidocaine or the control groups...
November 28, 2016: World Journal of Surgery
https://www.readbyqxmd.com/read/27850422/784-continuous-lidocaine-infusion-as-adjunctive-analgesia-in-intensive-care-unit-patients
#4
Yoonsun Mo, Michael Thomas, Abigail Antigua, Alex Ebied, George Karras
No abstract text is available yet for this article.
December 2016: Critical Care Medicine
https://www.readbyqxmd.com/read/27843772/long-term-evaluation-of-continuous-epidural-anesthesia-in-an-improved-canine-model
#5
Kyoko Sasauchi, Katsuhisa Sunada, Tatsuo Nakamura
BACKGROUND: Continuous epidural analgesia with catheterization is a useful technique, because it has a wide adaptation range and provides prolonged analgesia. Problems that may arise from long-term epidural analgesia are changes in the analgesic area, duration of analgesia and catheter-related problems. Few articles have evaluated gradual changes of long-term epidural analgesia. In the animal models used in those studies, the catheter was inserted by an invasive surgical procedure. In the present study, we evaluated changes in a canine model in which the catheter was inserted by a minimally invasive procedure...
August 2016: Anesthesiology and Pain Medicine
https://www.readbyqxmd.com/read/27806432/the-hippocampus-integrates-context-and-shock-into-a-configural-memory-in-contextual-fear-conditioning
#6
Shih-Dar Chang, K C Liang
Contextual fear conditioning involves forming a representation for the context and associating it with a shock, which were attributed by the prevailing view to functions of the hippocampus and amygdala respectively. Yet our recent evidence suggested that both processes require integrity of the dorsal hippocampus (DH). In view of the DH involvement in uniting multiple stimuli into a configuration, this study examined whether the DH would integrate context and shock into a shocked-context representation. Male Wistar rats were trained on a two-phase training paradigm of contextual fear conditioning...
November 2, 2016: Hippocampus
https://www.readbyqxmd.com/read/27785582/effects-of-cardiac-output-on-the-initial-distribution-volume-of-glucose-in-the-absence-of-fluid-gain-or-loss-in-pigs
#7
Toshinori Kasai, Eiji Hashiba, Junichi Saito, Kazuyoshi Hirota
: The initial distribution volume of glucose (IDVG) has been reported to be a surrogate marker of cardiac preload. However, the relationship between cardiac output and IDVG is not fully understood. We investigated the effects of cardiac output on IDVG in the absence of fluid gain or loss in pigs. MATERIALS AND METHODS: Thirteen pigs were anesthetized and allocated to either the modified cardiac output group (m-CO group, n = 10) or the control group (control group, n = 3)...
October 26, 2016: Journal of Anesthesia
https://www.readbyqxmd.com/read/27687366/randomized-comparison-of-the-feasibility-of-three-anesthetic-techniques-for-day-case-open-inguinal-hernia-repair
#8
Pertti Pere, Jukka Harju, Pekka Kairaluoma, Veikko Remes, Päivi Turunen, Per H Rosenberg
STUDY OBJECTIVE: Comparison of local anesthetic infiltration (LAI), spinal anesthesia (SPIN) and total intravenous anesthesia (TIVA) for open inguinal herniorrhaphy. We hypothesized that patients receiving LAI could be discharged faster than SPIN and TIVA patients. DESIGN: Randomized, prospective trial. SETTING: University hospital day-surgery center. PATIENTS: 156 adult male patients (ASA 1-3) undergoing day-case open inguinal herniorrhaphy...
November 2016: Journal of Clinical Anesthesia
https://www.readbyqxmd.com/read/27642575/severe-respiratory-event-initially-thought-to-be-inadvertent-endobronchial-intubation-possible-complications-from-using-of-a-topical-metered-dose-of-8-lidocaine-pump-spray
#9
Young-Chang P Arai, Jun Kawanishi, Yoshikazu Sakakima, Koichi Ohmoto, Akihiro Ito, Yuki Maruyama, Tatsunori Ikemoto
INTRODUCTION: Pulmonary collapse after intubation is common, and it is caused by a variety of factors. CASE PRESENTATION: A 21-year-old man presented at our operation room to undergo an appendectomy. Except for a history of cigarette smoking, his history was negative. Anesthesia was induced with 100% oxygen and sevoflurane, remifentanil infusion, and propofol. Neuromuscular block was obtained with rocuronium. The tip and cuff of a tracheal tube were lubricated with a topical metered-dose of 8% Lidocaine pump spray...
June 2016: Anesthesiology and Pain Medicine
https://www.readbyqxmd.com/read/27612660/serum-concentration-of-ketamine-and-antinociceptive-effects-of-ketamine-and-ketamine-lidocaine-infusions-in-conscious-dogs
#10
Ubedullah Kaka, Bullo Saifullah, Adamu Abdul Abubakar, Yong Meng Goh, Sharida Fakurazi, Asmatullah Kaka, Atique Ahmed Behan, Mahdi Ebrahimi, Hui Cheng Chen
BACKGROUND: Central sensitization is a potential severe consequence of invasive surgical procedures. It results in postoperative and potentially chronic pain enhancement. It results in postoperative pain enhancement; clinically manifested as hyperalgesia and allodynia. N-methyl-D-aspartate (NMDA) receptor plays a crucial role in the mechanism of central sensitisation. Ketamine is most commonly used NMDA-antagonist in human and veterinary practice. However, the antinociceptive serum concentration of ketamine is not yet properly established in dogs...
September 9, 2016: BMC Veterinary Research
https://www.readbyqxmd.com/read/27585569/visual-and-noxious-electrical-stimulus-evoked-membrane-potential-responses-in-anterior-cingulate-cortical-neurons
#11
Li-Qing Ma, Li Ning, Zhiru Wang, Ying-Wei Wang
Anterior cingulate cortex (ACC) is known to participate in numerous brain functions, such as memory storage, emotion, attention, as well as perception of acute and chronic pain. ACC-dependent brain functions often rely on ACC processing of various forms of environmental information. To understand the neural basis of ACC functions, previous studies have investigated ACC responses to environmental stimulation, particularly complex sensory stimuli as well as award and aversive stimuli, but this issue remains to be further clarified...
2016: Molecular Brain
https://www.readbyqxmd.com/read/27581435/small-volume-adenosine-lidocaine-and-mg2-4-hour-infusion-leads-to-88-survival-after-6-days-of-experimental-sepsis-in-the-rat-without-antibiotics
#12
Maddison Jade Griffin, Hayley Louise Letson, Geoffrey Phillip Dobson
Innovative host-directed drug therapies are urgently required to treat sepsis. We tested the effect of a small-volume 0.9% NaCl adenosine, lidocaine, and Mg(2+) (ALM) bolus and a 4-h intravenous infusion on survivability in the rat model of polymicrobial sepsis over 6 days. ALM treatment led to a significant increase in survivability (88%) compared to that of controls (25%). Four controls died on day 2 to 3, and two died on day 5. Early death was associated with elevated plasma and lung inflammatory markers (interleukin-6 [IL-6], IL-1β, C-reactive protein), reduced white blood cell (WBC) count, hypoxemia, hypercapnia, acidosis, hyperkalemia, and elevated lactate, whereas late death was associated with a massive cytokine storm, a neutrophil-dominated WBC rebound/overshoot, increased lung oxidant injury, edema, and persistent ischemia...
November 2016: Clinical and Vaccine Immunology: CVI
https://www.readbyqxmd.com/read/27572548/the-effect-of-dexmedetomidine-pretreatment-on-the-median-effective-bolus-dose-of-propofol-for-facilitating-laryngeal-mask-airway-insertion
#13
Ji Young Yoo, Hyun Jeong Kwak, Yong Beom Kim, Chu Kyung Park, Sook Young Lee, Jong Yeop Kim
BACKGROUND: We designed this study to investigate the effect of dexmedetomidine (1 μg/kg) pretreatment on the median effective dose (ED50) of propofol for facilitating successful laryngeal mask airway (LMA) insertion compared to propofol alone. METHODS: Forty patients were randomized to either the control group (n = 21) or the dexmedetomidine group (n = 19). After infusion of normal saline or dexmedetomidine 1 µg/kg over 10 min, 1 % lidocaine 0.5 mg/kg, followed by propofol 2...
August 29, 2016: Journal of Anesthesia
https://www.readbyqxmd.com/read/27552062/intravenous-lidocaine-infusions-in-a-multidirectional-model-of-treatment-of-neuropathic-pain-patients
#14
Anna Przeklasa-Muszyńska, Magdalena Kocot-Kępska, Jan Dobrogowski, Maciej Wiatr, Joanna Mika
BACKGROUND: Neuropathic pain, is caused by damage or disease affecting the somatosensory nervous system, leads to deterioration of the quality of life of patients. Most commonly, this deterioration is due to the inefficacy of treatment or to the adverse effects of systemic treatment. Pharmacotherapy of neuropathic pain involves the use of antiepileptic agents, antidepressants, and opioids that may lead to numerous adverse effects, particularly in elderly patients. Intravenous infusions of lidocaine may improve the efficacy of the analgesic treatment of neuropathic pain patients while not causing any significant adverse effects...
October 2016: Pharmacological Reports: PR
https://www.readbyqxmd.com/read/27550949/an-evidence-based-review-of-the-efficacy-of-perioperative-analgesic-techniques-for-breast-cancer-related-surgery
#15
Gloria S Cheng, Brian M Ilfeld
OBJECTIVE: To review the published evidence regarding perioperative analgesic techniques for breast cancer-related surgery. DESIGN: Topical review. METHODS: Randomized, controlled trials (RCTs) were selected for inclusion in the review. Also included were large prospective series providing estimates of potential risks and technical reports and small case series demonstrating a new technique or approaches of interest to clinicians. RESULTS: A total of 514 abstracts were reviewed, with 284 studies meeting criteria for full review...
August 22, 2016: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://www.readbyqxmd.com/read/27470233/effect-of-intravenous-lidocaine-on-the-transcerebral-inflammatory-response-during-cardiac-surgery-a-randomized-controlled-trial
#16
Rebecca Y Klinger, Mary Cooter, Miles Berger, Mihai V Podgoreanu, Mark Stafford-Smith, Thomas L Ortel, Ian J Welsby, Jerrold H Levy, Henry M Rinder, Mark F Newman, Joseph P Mathew
PURPOSE: Postoperative cognitive dysfunction (POCD) occurs frequently after cardiac surgery. The pathophysiology of POCD remains elusive, but previous work showed that intravenous lidocaine may be protective against POCD, possibly by modulating cerebral inflammation. We hypothesized that intravenous lidocaine would attenuate the cerebral inflammatory response to cardiopulmonary bypass (CPB) by reducing the transcerebral activation gradients of platelets, leukocytes, and/or platelet-leukocyte conjugates...
November 2016: Canadian Journal of Anaesthesia, Journal Canadien D'anesthésie
https://www.readbyqxmd.com/read/27427328/consolidation-of-altered-associability-information-by-amygdala-central-nucleus
#17
Felipe L Schiffino, Peter C Holland
The surprising omission of a reinforcer can enhance the associability of the stimuli that were present when the reward prediction error was induced, so that they more readily enter into new associations in the future. Previous research from this laboratory identified brain circuit elements critical to the enhancement of stimulus associability by the omission of an expected event and to the subsequent expression of that altered associability in more rapid learning. These elements include the amygdala, the midbrain substantia nigra, the basal forebrain substantia innominata, the dorsolateral striatum, the secondary visual cortex, and the posterior parietal cortex...
September 2016: Neurobiology of Learning and Memory
https://www.readbyqxmd.com/read/27423150/cardiopulmonary-effects-of-constant-rate-infusion-of-lidocaine-for-anesthesia-during-abdominal-surgery-in-goats
#18
Lais M Malavasi, Stephen A Greene, John M Gay, Tammy L Grubb
Lidocaine is commonly used in ruminants but has an anecdotal history of being toxic to goats. To evaluate lidocaine's effects on selected cardiopulmonary parameters. Isoflurane-anesthetized adult goats (n = 24) undergoing abdominal surgery received a loading dose of lidocaine (2.5 mg/kg) over 20 min followed by constant-rate infusion of lidocaine (100 μg/kg/min); control animals received saline instead of lidocaine. Data collected at predetermined time points during the 60-min surgery included heart rate, mean arterial blood pressure, pO2, and pCO2...
2016: Journal of the American Association for Laboratory Animal Science: JAALAS
https://www.readbyqxmd.com/read/27413480/presentation-of-neurolytic-effect-of-10-lidocaine-after-perineural-ultrasound-guided-injection-of-a-canine-sciatic-nerve-a-pilot-study
#19
David D Kim, Asma Asif, Sandeep Kataria
BACKGROUND: Phenol and alcohol have been used to ablate nerves to treat pain but are not specific for nerves and can damage surrounding soft tissue. Lidocaine at concentrations > 8% injected intrathecal in the animal model has been shown to be neurotoxic. Tests the hypothesis that 10% lidocaine is neurolytic after a peri-neural blockade in an ex vivo experiment on the canine sciatic nerve. METHODS: Under ultrasound, one canine sciatic nerve was injected peri-neurally with 10 cc saline and another with 10 cc of 10% lidocaine...
July 2016: Korean Journal of Pain
https://www.readbyqxmd.com/read/27382247/a-comparison-of-patient-pain-and-visual-outcome-using-topical-anesthesia-versus-regional-anesthesia-during-cataract-surgery
#20
Yoshikatsu Hosoda, Shoji Kuriyama, Yoko Jingami, Hidetsugu Hattori, Hisako Hayashi, Miho Matsumoto
PURPOSE: The purpose of this study was to compare the level of patient pain during the phacoemulsification and implantation of foldable intraocular lenses while under topical, intracameral, or sub-Tenon lidocaine. PATIENTS AND METHODS: This was a retrospective study. Three hundred and one eyes subjected to cataract surgery were included in this study. All eyes underwent phacoemulsification surgery and intraocular lens implantation using topical, sub-Tenon, or intracameral anesthesia...
2016: Clinical Ophthalmology
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