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https://www.readbyqxmd.com/read/28340029/the-proportion-of-errors-in-medical-prescriptions-and-their-executions-among-hospitalized-children-before-and-during-accreditation
#1
Tal Margalit Mekory, Hilla Bahat, Benjamin Bar-Oz, Orna Tal, Matitiahu Berkovitch, Eran Kozer
Objective: To evaluate the rate of medication related errors in the pediatric ward and pediatric emergency department (PED), before and after implementing intervention strategies according to the Joint Commission International (JCI) accreditation program. Design: A retrospective cross-sectional study that included chart review. Setting: A university affiliated pediatric ward and PED. Participants: Children 0-18 years old admitted on February 2013 (before the JCI program) and February 2014 (during implementation of the JCI program)...
March 10, 2017: International Journal for Quality in Health Care
https://www.readbyqxmd.com/read/28336128/retinal-pigment-epithelium-tears-classification-pathogenesis-predictors-and-management
#2
REVIEW
Mehmet Giray Ersoz, Murat Karacorlu, Serra Arf, Isil Sayman Muslubas, Mumin Hocaoglu
Various eye conditions cause tears in the retinal pigment epithelium (RPE). The most common cause of an RPE tear is vascularized retinal pigment epithelial detachment (PED) in patients with exudative age-related macular degeneration. Although RPE tears can develop spontaneously in vascularized PEDs, most recent cases have been associated with anti-vascular endothelial growth factor (VEGF) injections. The subretinal fluid within the PED applies hydrostatic pressure to the RPE and stretches it. The PED enlarges as the hydrostatic pressure increases...
March 20, 2017: Survey of Ophthalmology
https://www.readbyqxmd.com/read/28335505/porcine-epidemic-diarrhea-virus-induces-autophagy-to-benefit-its-replication
#3
Xiaozhen Guo, Mengjia Zhang, Xiaoqian Zhang, Xin Tan, Hengke Guo, Wei Zeng, Guokai Yan, Atta Muhammad Memon, Zhonghua Li, Yinxing Zhu, Bingzhou Zhang, Xugang Ku, Meizhou Wu, Shengxian Fan, Qigai He
The new porcine epidemic diarrhea (PED) has caused devastating economic losses to the swine industry worldwide. Despite extensive research on the relationship between autophagy and virus infection, the concrete role of autophagy in porcine epidemic diarrhea virus (PEDV) infection has not been reported. In this study, autophagy was demonstrated to be triggered by the effective replication of PEDV through transmission electron microscopy, confocal microscopy, and Western blot analysis. Moreover, autophagy was confirmed to benefit PEDV replication by using autophagy regulators and RNA interference...
March 19, 2017: Viruses
https://www.readbyqxmd.com/read/28332378/quantitative-computed-tomographic-volumetry-after-treatment-of-a-giant-intracranial-aneurysm-with-a-pipeline-embolization-device
#4
Woong Jae Lee, Jun Soo Byun, Jae Kyun Kim, Taek Kyun Nam
Recently developed flow diverters, such as the pipeline embolization device (PED), allow for safe and efficacious treatment of giant intracranial aneurysms, with high occlusion rates and a low incidence of complications. However, incomplete obliteration after PED treatment may lead to aneurysm regrowth and delayed rupture. Herein, we report a case of a partially thrombosed giant aneurysm of the cavernous internal carotid artery that showed progressive recanalization at 1-3 months after application of a PED...
May 2017: Yonsei Medical Journal
https://www.readbyqxmd.com/read/28323708/fenestrated-screws-augmented-with-pmma-increase-the-pullout-strength-of-sacral-pedicle-screws
#5
Matthew Colman, Jonathan Pond, Kent Bachus, Brandon D Lawrence, William R Spiker, Darrel S Brodke
STUDY DESIGN: Biomechanics. OBJECTIVE: The objective of this study was to compare the fixation in osteoporotic specimens of a bicortical sacral pedicle screw to the following constructs: a unicortical solid screw augmented with polymethylmethacrylate (PMMA) (TRACT), a unicortical fenestrated screw augmented with PMMA (FEN), and a bicortical screw/sacral alar screw combination (PED/ALA). SUMMARY OF BACKGROUND DATA: Rigid posterior sacral fixation of osteoporotic spines is problematic due to poor bone quality...
April 2017: Clinical Spine Surgery
https://www.readbyqxmd.com/read/28320029/morphometric-changes-of-the-lumbar-intervertebral-foramen-after-percutaneous-endoscopic-foraminoplasty-under-local-anesthesia
#6
Tatsuhiko Henmi, Tomoya Terai, Akihiro Nagamachi, Koichi Sairyo
Background Percutaneous endoscopic diskectomy (PED) for the lumbar spine is a relatively new technique that is becoming more common due to its relatively less invasive nature. However, one possible serious complication is an exiting nerve injury when the cannula of the endoscope is inserted into the neural canal through the intervertebral foramen. A technique to enlarge the intervertebral foramen, called foraminoplasty, was recently established to insert the cannula safely into an appropriate position in the neural canal...
March 20, 2017: Journal of Neurological Surgery. Part A, Central European Neurosurgery
https://www.readbyqxmd.com/read/28316868/a-case-of-ruptured-blood-blister-like-aneurysm-treated-with-pipeline-embolization-device-clinical-significance-of-fetal-type-posterior-communicating-artery
#7
Ki-Su Park, Dong-Hun Kang, Won-Soo Son, Jaechan Park, Young-Sun Kim, Byung Moon Kim
Blood-blister like aneurysms (BBAs) are challenging lesions because of their wide fragile neck. Flow-diverting stents (FDSs), such as the Pipeline Embolization Device (PED), have been applied to treat BBAs less amenable to more established techniques of treatment. However, the use of FDSs, including the PED, in acute subarachnoid hemorrhage (SAH) still remains controversial. We report a case of aneurysm regrowth following PED application for a ruptured BBA that overlapped the origin of the dominant posterior communicating artery (PCoA), which was successfully treated after coil trapping of the origin of the fetal-type PCoA...
March 2017: Neurointervention
https://www.readbyqxmd.com/read/28304204/changes-in-contrast-transit-times-on-digital-subtraction-angiography-post-pipeline-embolization-device-deployment
#8
Ahmed E Hussein, Andreas Linninger, Sophia F Shakur, Fady T Charbel, Chih-Yang Hsu, Fady T Charbel, Ali Alaraj
It is postulated that hemodynamic changes occur in the distal vascular bed post-deployment of Pipeline Embolization Devices (PEDs). In this paper, we evaluate changes in the contrast transit times (TTs) on digital subtraction angiography (DSA) post-PED interventions. DSA films were analyzed using custom-made software for the time-density relationship at baseline and compared to post-PED deployment. All analyses were performed within the middle cerebral artery (MCA) M1 segment. Analyses included TT10%-100% (time needed for the contrast to change from 10% image intensity to 100%), TT100%-10%, and TT25%-25%...
April 2017: Interventional Neuroradiology
https://www.readbyqxmd.com/read/28296533/polypharmacy-infectious-diseases-sexual-behavior-and-psychophysical-health-among-anabolic-steroid-using-homosexual-and-heterosexual-gym-patrons-in-san-francisco-s-castro-district
#9
Eric J Ip, Michael A Yadao, Bijal M Shah, Shadi Doroudgar, Paul J Perry, Michael J Tenerowicz, Lindsay Newsom, Amber A Mann, Hermine Mkrtchyan, Harrison G Pope
BACKGROUND: Limited studies based in England and Australia reported misuse of anabolic-androgenic steroids (AAS) among homosexual men to enhance body image. Anecdotally, AAS are also being misused by homosexual men in the United States. Since many AAS and certain performance enhancing drugs (PEDs) are administered via injection, this poses a potential vector for the spread of infectious disease in an already at-risk population. OBJECTIVES: This study compared and contrasted homosexual and heterosexual male gym clients regarding use of AAS and PEDs, use of alcohol and illicit drugs, seroprevalence of infectious disease, engagement in risky injection practices and sexual behaviors, and presence of psychiatric conditions...
March 15, 2017: Substance Use & Misuse
https://www.readbyqxmd.com/read/28293079/pediatric-gastrointestinal-bleeding-perspectives-from-the-italian-society-of-pediatric-gastroenterology
#10
REVIEW
Claudio Romano, Salvatore Oliva, Stefano Martellossi, Erasmo Miele, Serena Arrigo, Maria Giovanna Graziani, Sabrina Cardile, Federica Gaiani, Gian Luigi de'Angelis, Filippo Torroni
There are many causes of gastrointestinal bleeding (GIB) in children, and this condition is not rare, having a reported incidence of 6.4%. Causes vary with age, but show considerable overlap; moreover, while many of the causes in the pediatric population are similar to those in adults, some lesions are unique to children. The diagnostic approach for pediatric GIB includes definition of the etiology, localization of the bleeding site and determination of the severity of bleeding; timely and accurate diagnosis is necessary to reduce morbidity and mortality...
February 28, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/28289563/persistent-erectile-dysfunction-in-men-exposed-to-the-5%C3%AE-reductase-inhibitors-finasteride-or-dutasteride
#11
Tina Kiguradze, William H Temps, Paul R Yarnold, John Cashy, Robert E Brannigan, Beatrice Nardone, Giuseppe Micali, Dennis Paul West, Steven M Belknap
IMPORTANCE: Case reports describe persistent erectile dysfunction (PED) associated with exposure to 5α-reductase inhibitors (5α-RIs). Clinical trial reports and the manufacturers' full prescribing information (FPI) for finasteride and dutasteride state that risk of sexual adverse effects is not increased by longer duration of 5α-RI exposure and that sexual adverse effects of 5α-RIs resolve in men who discontinue exposure. OBJECTIVE: Our chief objective was to assess whether longer duration of 5α-RI exposure increases risk of PED, independent of age and other known risk factors...
2017: PeerJ
https://www.readbyqxmd.com/read/28284624/attenuation-of-an-original-us-porcine-epidemic-diarrhea-virus-strain-pc22a-via-serial-cell-culture-passage
#12
Chun-Ming Lin, Yixuan Hou, Douglas G Marthaler, Xiang Gao, Xinsheng Liu, Lanlan Zheng, Linda J Saif, Qiuhong Wang
Although porcine epidemic diarrhea (PED) has caused huge economic losses in the pork industry worldwide, an effective live, attenuated vaccine is lacking. In this study, an original US, highly virulent PED virus (PEDV) strain PC22A was serially passaged in Vero CCL81 and Vero BI cells. The virus growth kinetics in cell culture, virulence in neonatal pigs and the whole genomic sequences of selected passages were examined. Increased virus titers and sizes of syncytia were observed at the 65th passage level (P65) and P120, respectively...
March 2017: Veterinary Microbiology
https://www.readbyqxmd.com/read/28281162/the-effect-of-porcine-epidemic-diarrhea-ped-on-ovarian-function-and-reproductive-performance-after-weaning-in-berkshire-sows
#13
Yosuke Sasaki, Tadahiro Kawabata, Michiko Noguchi
The purpose of this study was to investigate the ovarian condition at weaning and subsequent reproductive performance of Berkshire sows following an outbreak of PED. This study was conducted on a farrow-to-finish farm that experienced a PED outbreak beginning on January 6, 2014. Blood samples were collected at weaning from 19 to 20 sows every month from July 2013 until July 2014 to investigate the ovarian condition. The mean progesterone concentration was numerically higher during January 2014 than the other months, but this difference was not significant...
March 10, 2017: Tropical Animal Health and Production
https://www.readbyqxmd.com/read/28280989/the-role-of-pigment-epithelial-detachment-in-amd-with-submacular-hemorrhage-treated-with-vitrectomy-and-subretinal-co-application-of-rtpa-and-anti-vegf
#14
F Treumer, S Wienand, K Purtskhvanidze, J Roider, J Hillenkamp
PURPOSE: To assess the incidence of pigment epithelial detachment (PED) in age-related macular degeneration (AMD) with submacular hemorrhage (SMH) and its response to treatment with pars plana vitrectomy (ppV), subretinal co-application of recombinant tissue plasminogen activator (rtPA) and anti-VEGF, and an intravitreal gas tamponade. METHODS: Consecutive interventional case series of 132 eyes of 129 patients with neovascular AMD with SMH. All eyes underwent ppV with subretinal co-application of rtPA and bevacizumab followed by a gas tamponade...
March 9, 2017: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/28272972/a-feasibility-study-using-solution-focused-coaching-for-health-promotion-in-children-and-young-people-with-duchenne-muscular-dystrophy
#15
Amy C McPherson, Laura McAdam, Sarah Keenan, Heidi Schwellnus, Elaine Biddiss, Andrea DeFinney, Kirsten English
PURPOSE: To evaluate the feasibility and acceptability of a coaching intervention (Solution-Focused Coaching in pediatric rehabilitation [SFC-Peds]) related to physical activity and diet in males with Duchenne muscular dystrophy. METHODS: A pre-post design was employed. Participants had five coaching sessions over 8 weeks. The first session was face-to-face, followed by four virtual sessions. Feasibility criteria included recruitment rates, attrition, and intervention fidelity...
March 8, 2017: Developmental Neurorehabilitation
https://www.readbyqxmd.com/read/28267114/optical-coherence-tomography-angiography-of-flat-irregular-pigment-epithelium-detachment-in-chronic-central-serous-chorioretinopathy
#16
Elodie Bousquet, Sophie Bonnin, Sarah Mrejen, Valérie Krivosic, Ramin Tadayoni, Alain Gaudric
PURPOSE: To assess the rate of choroidal neovascularization (CNV) detected by optical coherence tomography angiography (OCTA) in flat irregular pigment epithelium detachment (PED) in chronic central serous chorioretinopathy. METHODS: Data on all consecutive patients with chronic central serous chorioretinopathy who underwent OCTA over a 1-year period were reviewed. The presence of flat irregular PED, which was defined as an irregular elevation of the retinal pigment epithelium allowing the visualization of a distinct Bruch's membrane was assessed on high-resolution OCT B-scan...
March 3, 2017: Retina
https://www.readbyqxmd.com/read/28265011/tourniquet-parent-artery-occlusion-after-flow-diversion
#17
Visish M Srinivasan, Maxim Mokin, Edward A M Duckworth, Stephen Chen, Ajit Puri, Peter Kan
BACKGROUND: The Pipeline Embolization Device (PED) is increasingly used for both on- and off-label purposes for treatment of intracranial aneurysms. The device gradually slows flow of blood into the aneurysm, but the high metal coverage of PED promotes endothelialization of the device. Occasionally, this leads to in-stent stenosis that is clinically well tolerated. We present a multi-institutional Pipeline series that includes three cases of gradual asymptomatic occlusion within the PED and parent vessel...
March 6, 2017: Journal of Neurointerventional Surgery
https://www.readbyqxmd.com/read/28253042/monitoring-elite-soccer-players-external-loads-using-real-time-data
#18
Steve Barrett
PURPOSE: The principle aim of the study was to assess the validity of measuring locomotor activities and PlayerLoad using Real-Time (RT) data collection during soccer training. METHODS: Twenty-nine (n=29) English soccer players participated. Each player wore the same MEMS device (S5, Optimeye, CatapultSports, Melbourne, Australia) during twenty-one training sessions (n= 331 data sets) in the 2015/2016 and 2016/2017 season. A Real-Time receiver (TRX, Catapultsports, Melbourne, Australia) was used to collect the locomotor activities and PlayerLoad data in RT and compared with the post-event downloaded (PED) data...
March 2, 2017: International Journal of Sports Physiology and Performance
https://www.readbyqxmd.com/read/28241322/three-dimensional-analysis-of-morphologic-changes-and-visual-outcomes-in-neovascular-age-related-macular-degeneration
#19
Hyungwoo Lee, Aerin Jo, Hyung Chan Kim
Purpose: To investigate the association of three-dimensionally quantified lesions with best-corrected visual acuity (BCVA) in typical neovascular age-related macular degeneration (nAMD). Methods: We retrospectively analyzed 65 eyes of 61 typical nAMD patients. Lesions at baseline and month 12 were manually delineated in optical coherence tomography. The volume of intraretinal fluid (IRF), subretinal fluid (SRF), subretinal hyperreflective material (SHRM), and pigment epithelial detachment (PED) were measured...
February 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/28240649/can-we-identify-parents-who-do-not-verbally-share-concerns-for-their-children-s-development
#20
Matthew Eremita, Eileen Semancik, Trudy Lerer, Paul H Dworkin
OBJECTIVE: We aimed to identify characteristics of parents who do not voice developmental concerns when prompted by their children's nurse and/or primary care provider (PCP), despite reporting concerns on parent-completed questionnaires. METHODS: We reviewed 376 medical records of children seen for a 9-month well-child visit in an urban pediatric clinic between September 2011 and December 2012 for sociodemographic variables hypothesized to affect parents' sharing of developmental concerns: the child's birth order and gender; parents' education level, employment, relationship status, and primary language; and family size and racial/ethnic background...
February 23, 2017: Journal of Developmental and Behavioral Pediatrics: JDBP
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