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https://www.readbyqxmd.com/read/28642752/a-comprehensive-epidemiological-research-for-clinical-vibrio-parahaemolyticus-in-shanghai
#1
Huan Li, Rong Tang, Yang Lou, Zelin Cui, Wenjing Chen, Qing Hong, Zhaohuan Zhang, Pradeep K Malakar, Yingjie Pan, Yong Zhao
Vibrio parahaemolyticus is one of the most important pathogen for seafood-borne gastroenteritis in Shanghai and the rest of the world. A total of 42 V. parahaemolyticus strains were isolated from 1900 fecal specimens collected from patients in Shanghai hospital presenting from January 2014 to December 2015. All isolates were evaluated for potential virulence factors [tdh, trh, and type three secretion system (T3SS) genes], typed using multilocus sequence typing (MLST) and screened for antimicrobial resistance phenotype and genotype...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28640905/an-efficient-method-for-transgenic-callus-induction-from-vitis-amurensis-petiole
#2
Tingting Zhao, Zemin Wang, Lingye Su, Xiaoming Sun, Jun Cheng, Langlang Zhang, Sospeter Karanja Karungo, Yuepeng Han, Shaohua Li, Haiping Xin
Transformation is the main platform for genetic improvement and gene function studies in plants. However, the established somatic embryo transformation system for grapevines is time-consuming and has low efficiency, which limits its utilization in functional genomics research. Vitis amurensis is a wild Vitis species with remarkable cold tolerance. The lack of an efficient genetic transformation system for it has significantly hindered the functional identification of cold stress related genes in the species...
2017: PloS One
https://www.readbyqxmd.com/read/28640870/dominance-of-community-associated-methicillin-resistant-staphylococcus-aureus-clones-in-a-maternity-hospital
#3
Edet E Udo, Noura Al-Sweih
BACKGROUND: Methicillin- resistant Staphylococcus aureus (MRSA) is a major pathogen causing healthcare- and community- acquired infections. The purpose of this study was to characterize MRSA isolated at the Maternity Hospital between 2006 and 2011 for their genetic relatedness. MATERIALS AND METHODS: The MRSA isolates were investigated using a combination of antibiogram, Staphylococcal chromosome cassette mec (SCCmec) and spa typing to determine their relatedness to MRSA isolated in other Kuwait hospitals...
2017: PloS One
https://www.readbyqxmd.com/read/28639565/diagnostic-performance-of-the-genotype-mtbdrplus-and-mtbdrsl-assays-to-identify-tuberculosis-drug-resistance-in-eastern-china
#4
Qiao Liu, Guo-Li Li, Cheng Chen, Jian-Ming Wang, Leonardo Martinez, Wei Lu, Li-Mei Zhu
BACKGROUND: The WHO recently has recommended the GenoType MTBDRplus version 1.0 and MTBDRsl version 1.0 assays for widespread use in countries endemic with drug-resistant tuberculosis. Despite this, these assays have rarely been evaluated in China, where the burden of drug-resistant tuberculosis is among the highest globally. METHODS: Mycobacterium tuberculosis clinical isolates were obtained between January 2008 and December 2008. Isolates were tested for drug resistance against rifampicin (RFP) and isoniazid (INH) using the GenoType MTBDRplus assay and drug resistance against ethambutol (EMB), ofloxacin (OFX), and kanamycin (KM) using the Genotype MTBDRsl assay...
July 5, 2017: Chinese Medical Journal
https://www.readbyqxmd.com/read/28630205/the-impact-of-gyrb-and-eis-mutations-in-improving-second-line-drug-resistance-detection-among-mycobacterium-tuberculosis-isolates-from-georgia
#5
N Bablishvili, N Tukvadze, E Shashkina, B Mathema, N R Gandhi, H M Blumberg, R R Kempker
SETTING: The country of Georgia has a high burden of multi- and extensively drug-resistant tuberculosis (XDR-TB).OBJECTIVE: To evaluate whether the detection of mutations in gyrB and eis genes increased the sensitivity of detecting phenotypic resistance to ofloxacin and kanamycin or capreomycin as compared to use of the first generation MTBDRsl assay alone which evaluates for mutations in gyrA and rrs genes.DESIGN: A retrospective study of storedMycobacterium tuberculosis isolates. All isolates underwent DNA sequencing of resistance determining regions...
June 19, 2017: Antimicrobial Agents and Chemotherapy
https://www.readbyqxmd.com/read/28625768/screening-and-characterization-of-lactic-acid-bacterial-strains-that-produce-fermented-milk-and-reduce-cholesterol-levels
#6
Xuefang Guan, Qingxian Xu, Yi Zheng, Lei Qian, Bin Lin
OBJECTIVE: To screen for and characterize lactic acid bacteria strains with the ability to produce fermented milk and reduce cholesterol levels. METHODS: The strains were isolated from traditional fermented milk in China. In vitro and in vivo evaluation of cholesterol-reduction were used to identify and verify strains of interest. Characteristics were analyzed using spectrophotometry and plate counting assays. RESULTS: The isolate HLX37 consistently produced fermented milk with strong cholesterol-reducing properties was identified as Lactobacillus plantarum (accession number: KR105940) and was thus selected for further study...
June 2, 2017: Brazilian Journal of Microbiology: [publication of the Brazilian Society for Microbiology]
https://www.readbyqxmd.com/read/28623821/green-biosynthesis-of-magnetic-iron-oxide-fe3o4-nanoparticles-using-the-aqueous-extracts-of-food-processing-wastes-under-photo-catalyzed-condition-and-investigation-of-their-antimicrobial-and-antioxidant-activity
#7
Jayanta Kumar Patra, Kwang-Hyun Baek
In this study, a simple, rapid, and eco-friendly green method was introduced to synthesize magnetite iron oxide nanoparticles (Fe3O4 NPs) using the aqueous extracts of two food processing wastes, namely silky hairs of corn (Zea mays L.) and outer leaves of Chinese cabbage (Brassica rapa L. subsp. pekinensis). The boiled solutions of silky hairs (MH) and outer leaves of Chinese cabbage (CCP) were used to synthesize Fe3O4 NPs under photo exposed condition. The MH-FeNPs and CCP-FeNPs synthesized via green route were characterized by UV-Vis spectroscopy, field emission scanning electron microscopy (FE-SEM), energy-dispersive X-ray spectroscopy (EDX), Fourier-transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD), differential thermogravimetric (TG/DTG) analysis, and vibrating sample magnetometer (VSM) analysis...
June 8, 2017: Journal of Photochemistry and Photobiology. B, Biology
https://www.readbyqxmd.com/read/28620453/parallel-pathways-in-the-biosynthesis-of-aminoglycoside-antibiotics
#8
REVIEW
Yi Yu, Qi Zhang, Zixin Deng
Despite their inherent toxicity and the global spread of bacterial resistance, aminoglycosides (AGs), an old class of microbial drugs, remain a valuable component of the antibiotic arsenal. Recent studies have continued to reveal the fascinating biochemistry of AG biosynthesis and the rich potential in their pathway engineering. In particular, parallel pathways have been shown to be common and widespread in AG biosynthesis, highlighting nature's ingenuity in accessing diverse natural products from a limited set of genes...
2017: F1000Research
https://www.readbyqxmd.com/read/28620262/prevalence-of-multiple-drug-resistant-streptococcus-suis-in-and-around-guwahati-india
#9
Mrinalee Devi, Jyoti B Dutta, Swaraj Rajkhowa, Dhireswar Kalita, Girindra Kumar Saikia, Bipin Chandra Das, Razibuddin Ahmed Hazarika, Gauranga Mahato
AIM: This study was conducted to determine the prevalence and antimicrobial susceptibility of Streptococcus suis and their resistance patterns isolated from both clinically healthy carriers and diseased pigs in and around Guwahati, Assam, India. MATERIALS AND METHODS: A total of 497 samples were collected during October, 2012, to April, 2014, from clinically healthy (n=67) and diseased (n=230) pigs of varying age and either sex maintained under organized and unorganized farming systems...
May 2017: Veterinary World
https://www.readbyqxmd.com/read/28615866/virulence-assay-and-role-of-bacillus-thuringiensis-ts110-as-biocontrol-agent-against-the-larval-stages-of-rice-leaffolder-cnaphalocrocis-medinalis
#10
Tuhin Subhra Ghosh, Soumendranath Chatterjee, Syed Afrin Azmi, Abhijit Mazumdar, Tushar Kanti Dangar
The bacterial isolate Bacillus thuringiensis TS110 was isolated from the rice field soil of Burdwan district, West Bengal, India. Bioassay test of the bacteria TS110 against 3rd, 4th and 5th instar larvae of Cnaphalocrocis medinalis was carried out. Cut leaf assay, potted plant assay and field assay were done. During filed assay, it has been observed that the LC50 (×10(7)) values of TS110 against 3rd, 4th and 5th instar larvae of C. medinalis were 3.77, 5.29, 4.83 and 4.93, 4.42, 4.72 in dry and wet season, respectively...
June 2017: Journal of Parasitic Diseases: Official Organ of the Indian Society for Parasitology
https://www.readbyqxmd.com/read/28611000/the-sterility-of-selected-operative-sites-during-total-laparoscopic-hysterectomy
#11
Marie E Shockley, Benjamin Beran, Heather Nutting, Katrin Arnolds, Michael L Sprague, Stephen Zimberg
STUDY OBJECTIVE: To describe the type and quantity of bacteria found intraoperatively on the abdomen, vagina, surgical gloves, instrument tips, and uterus at distinct time points during total laparoscopic hysterectomy (TLH). DESIGN: Observational study (Canadian Task Force classification III) SETTING: Academic affiliated hospital PATIENTS: 31 women undergoing TLH for benign indications in 2016 INTERVENTIONS: After antibiotic prophylaxis and chlorhexidine preparation, swabs were collected from the vaginal fornices and abdomen...
June 10, 2017: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/28605961/species-distribution-antibiotic-resistance-and-virulence-traits-in-canine-and-feline-enterococci-in-tunisia
#12
Leila Ben Said, Raoudha Dziri, Nadia Sassi, Carmen Lozano, Karim Ben Slama, Imen Ouzari, Carmen Torres, Naouel Klibi
In order to investigate the possible role of dogs and cats in the carriage and potential dissemination of resistant enterococci, seventy faecal samples from dogs and cats were tested for enterococci. Fifty-eight enterococci were recovered. Isolates were identified as Enterococcus faecium (n = 31) and E. faecalis (n = 14) E. durans (n = 6), E. casseliflavus (n = 2), E. hirae and E. gallinarum (2 isolates each). Enterococcal isolates showed resistance to ciprofloxacin (n = 35), erythromycin (n = 31), tetracycline (n = 25), kanamycin (n = 15), streptomycin (n = 13), pristinamycin (n = 11), gentamicin (n = 10), chloramphenicol (n = 8), and linezolid (n = 6)...
June 2017: Acta Veterinaria Hungarica
https://www.readbyqxmd.com/read/28601447/phenotypic-and-genotypic-antimicrobial-susceptibility-pattern-of-streptococcus-spp-isolated-from-cases-of-clinical-mastitis-in-dairy-cattle-in-poland
#13
E Kaczorek, J Małaczewska, R Wójcik, W Rękawek, A K Siwicki
Mastitis of dairy cattle is one of the most frequently diagnosed diseases worldwide. The main etiological agents of mastitis are bacteria of the genus Streptococcus spp., in which several antibiotic resistance mechanisms have been identified. However, detailed studies addressing this problem have not been conducted in north-eastern Poland. Therefore, the aim of our study was to analyze, on phenotypic and genotypic levels, the antibiotic resistance pattern of Streptococcus spp. isolated from clinical cases of mastitis from dairy cattle in this region of Poland...
June 7, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/28596137/reshaping-antibiotics-through-hydrophobic-drug-bile-acid-ionic-complexation-enhances-activity-against-staphylococcus-aureus-biofilms
#14
Stefano Giovagnoli, Donatella Pietrella, Lanfranco Barberini, Claudio Santi, Andrea Carotti, Alessandro di Michele, Maurizio Ricci
The antibiotic era is on the verge of a profound change and facing a ground shaking crisis. The frequent failures of antibiotic treatments are often associated with biofilm formation, which is responsible for chronic infections, exacerbation as well as reinfection. So far, albeit the large number of valuable strategies employed to combat biofilm formation, little success has been recorded. In this work, we propose a simple approach, based on hydrophobic ionic complexation with the bile acids, deoxycholic acid (DCA) and ursodeoxycholic acid (UDCA), to enhance anti-biofilm activity of well-known antibiotics, namely kanamycin (K), amikacin (A) and vancomycin (V)...
June 6, 2017: International Journal of Pharmaceutics
https://www.readbyqxmd.com/read/28583333/dry-powder-formulation-of-kanamycin-with-enhanced-aerosolization-efficiency-for-drug-resistant-tuberculosis
#15
Mohammad A M Momin, Shubhra Sinha, Ian G Tucker, Colin Doyle, Shyamal C Das
BACKGROUND: Kanamycin, an injectable agent, is currently used to treat drug-resistant tuberculosis (TB). Parenteral kanamycin causes high systemic toxicity which could be avoided by direct delivery to the lungs. This study focused on producing a highly aerosolizable dry-powder of hygroscopic kanamycin by spray-drying with l-leucine. METHODS: Kanamycin powders were prepared with different concentrations (0, 5, 10, 15 and 20% w/w) of l-leucine using the Buchi B-290 Mini Spray-Dryer...
June 3, 2017: International Journal of Pharmaceutics
https://www.readbyqxmd.com/read/28578167/novel-label-free-and-high-throughput-microchip-electrophoresis-platform-for-multiplex-antibiotic-residues-detection-based-on-aptamer-probes-and-target-catalyzed-hairpin-assembly-for-signal-amplification
#16
Ye Wang, Ning Gan, You Zhou, Tianhua Li, Futao Hu, Yuting Cao, Yinji Chen
Novel label-free and multiplex aptasensors have been developed for simultaneous detection of several antibiotics based on a microchip electrophoresis (MCE) platform and target catalyzed hairpin assembly (CHA) for signal amplification. Kanamycin (Kana) and oxytetracycline (OTC) were employed as models for testing the system. These aptasensors contained six DNA strands termed as Kana aptamer-catalysis strand (Kana apt-C), Kana inhibit strand (Kana inh), OTC aptamer-catalysis strand (OTC apt-C), OTC inhibit strand (OTC inh), hairpin structures H1 and H2 which were partially complementary...
May 10, 2017: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/28577759/pip40a-a-type-1-incc-plasmid-from-1969-carries-the-integrative-element-gisul2-and-a-novel-class-ii-mercury-resistance-transposon
#17
Christopher J Harmer, Mohammad Hamidian, Ruth M Hall
The 167.5kb sequence of the conjugative IncC plasmid pIP40a, isolated from a Pseudomonas aeruginosa in 1969, was analysed. pIP40a confers resistance to kanamycin, neomycin, ampicillin, sulphonamides and mercuric ions, and several insertions in a type 1 IncC backbone were found, including copies of IS3, Tn1000 and a novel mercury resistance transposon, Tn6182. The antibiotic resistance genes were in two locations. Tn6023, containing the aphA1 kanamycin and neomycin resistance gene, is in a partial copy of Tn1/Tn2/Tn3 (blaTEM, ampicillin resistance) in the kfrA gene, and the sul2 sulphonamide resistance gene is in the integrative element GIsul2 in the position of ARI-B islands...
May 31, 2017: Plasmid
https://www.readbyqxmd.com/read/28574626/assessment-of-phenotypic-and-genotypic-antibiotic-susceptibility-of-vaginal-lactobacillus-sp
#18
Jelena Štšepetova, Heleri Taelma, Imbi Smidt, Pirje Hütt, Eleri Lapp, Evi Aotäht, Reet Mändar
AIM: To assess antibiotic susceptibility of vaginal lactobacilli strains and provide the data required for assessing the potential of antibiotic resistance risk of new strains selected as probiotic. METHODS AND RESULTS: Potential probiotic vaginal lactobacilli used in the study included 31 vaginal strains of Lactobacillus crispatus, (n=27), L. gasseri (n=3) and L. jensenii (n=1) obtained from the collection of Competence Centre on Health Technologies. Two commercial probiotic strains were used as controls (L...
June 2, 2017: Journal of Applied Microbiology
https://www.readbyqxmd.com/read/28567636/biosorption-characteristic-of-alcaligenes-sp-bapb-1-for-removal-of-lead-ii-from-aqueous-solution
#19
Yu Jin, Sumei Yu, Chunying Teng, Tao Song, Liying Dong, Jinsong Liang, Xin Bai, Xiuhong Xu, Juanjuan Qu
In this study, strain BAPb.1 was isolated from lead mining area and used as an adsorbent to remove lead(II) ions from aqueous solution. The physicochemical characteristics, heavy metal resistance and antibiotic sensitivity of strain BAPb.1 were investigated. Biosorption capacity was evaluated by batch biosorption experiments, and isothermal characteristics were discussed. Atomic force microscopy (AFM), scanning electron microscopy (SEM), energy dispersive X-ray spectroscopy (EDX) and Fourier transform infrared spectrometry (FTIR) were conducted to explore the mechanism for lead(II) adsorption...
June 2017: 3 Biotech
https://www.readbyqxmd.com/read/28558683/inhibition-of-biofilm-formation-in-mycobacterium-smegmatis-by-parinari-curatellifolia-leaf-extracts
#20
Benjamin Bhunu, Ruvimbo Mautsa, Stanley Mukanganyama
BACKGROUND: Tuberculosis (TB) is a serious public health problem worldwide. Mycobacterium tuberculosis (M. tuberculosis) grows as drug tolerant pellicles. Agents that inhibit biofilm formation in M. tuberculosis have the potential to reduce the disease treatment period and improve the quality of tuberculosis chemotherapy. Parinari curatellifolia (P. curatellifolia) leaf extracts are claimed to treat symptoms similar to tuberculosis in ethnomedicinal practices. Mycobacterium smegmatis (M...
May 30, 2017: BMC Complementary and Alternative Medicine
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