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https://www.readbyqxmd.com/read/28326745/evaluation-of-the-psychometric-properties-of-the-brief-internalized-stigma-of-mental-illness-scale-ismi-10
#1
Marie Ociskova, Jan Prasko, Dana Kamaradova, Marketa Marackova, Michaela Holubova
OBJECTIVES: A significant number of psychiatric patients stigmatize themselves because of their mental struggles. Such self-stigmatization has an adverse impact on patients' well-being and effectiveness of the treatment of mental disorders. The goal of this study was to standardize the brief Internalized Stigma of Mental Illness Scale (ISMI-10), which could be used in studies targeting the self-stigma among the psychiatric patients. METHOD: 354 psychiatric patients participated in the study between the years 2012 and 2014...
December 2016: Neuro Endocrinology Letters
https://www.readbyqxmd.com/read/28282734/psychiatric-disorders-among-older-prisoners-a-systematic-review-and-comparison-study-against-older-people-in-the-community
#2
Claudio Di Lorito, Birgit Vӧllm, Tom Dening
OBJECTIVES: Despite emerging evidence that older prisoners experience poor mental health, literature in this area is still limited. In the present systematic review and meta-analysis, we report on the prevalence of psychiatric disorders among older prisoners and compare our findings against community studies on older people. METHODS: We searched on Assia, PsycInfo, MedLine, Embase, Web of Science, Google and Gov.uk. We carried out bias assessments, rated studies for quality and ran a heterogeneity test...
February 7, 2017: Aging & Mental Health
https://www.readbyqxmd.com/read/28262158/psychosis-as-a-late-manifestation-of-sheehan-s-syndrome
#3
Mukku Shiva Shanker Reddy, Abhinav Nahar, Harish Thippeswamy, Chaturvedi Santosh Kumar
Sheehan's syndrome occurs as a result of ischemic pituitary necrosis due to severe postpartum haemorrhage. It is one of the most common causes of hypopituitarism in underdeveloped or developing countries. Characteristic manifestations include failure to lactate or to resume menses, genital and axillary hair loss, asthenia and weakness, fine wrinkles around the eyes and lips, signs of premature aging, dry skin, hypopigmentation and other evidence of hypopituitarism. Uncommonly it can present with psychosis. There are only few case reports of psychoses in patients with Sheehan's syndrome...
February 2017: Asian Journal of Psychiatry
https://www.readbyqxmd.com/read/28258794/brain-bioenergetics-and-redox-state-measured-by-31-p-magnetic-resonance-spectroscopy-in-unaffected-siblings-of-patients-with-psychotic-disorders
#4
Virginie-Anne Chouinard, Sang-Young Kim, Linda Valeri, Cagri Yuksel, Kyle P Ryan, Guy Chouinard, Bruce M Cohen, Fei Du, Dost Öngür
BACKGROUND: Brain bioenergetic anomalies and redox dysregulation have been implicated in the pathophysiology of psychotic disorders. The present study examined brain energy-related metabolites and the balance between nicotinamide adenine dinucleotide metabolites (oxidized NAD+ and reduced NADH) using (31)P-magnetic resonance spectroscopy ((31)P-MRS) in unaffected siblings, compared to first episode psychosis (FEP) patients and healthy controls. METHODS: 21 unaffected siblings, 32 FEP patients (including schizophrenia spectrum and affective psychoses), and 21 controls underwent (31)P-MRS in the frontal lobe (6×6×4cm(3)) on a 4T MR scanner, using custom-designed dual-tuned surface coil with outer volume suppression...
March 1, 2017: Schizophrenia Research
https://www.readbyqxmd.com/read/28252603/-modeling-of-an-influence-of-indicators-of-social-stress-on-demographic-processes-in-regions-of-the-russian-federation
#5
M M Burkin, E V Molchanova
AIM: To assess an impact of indicators of social stress on demographic processes in regions of the Russian Federation using statistical methods. MATERIAL AND METHODS: The data of Rosstat «Regions of Russia» and «Health care in Russia» were used as information base. Indicators of about 80 subjects of the Russian Federation (without autonomous areas) for the ten-year period (2005-2014) have been created in the form of the database consisting of the following blocks: medico-demographic situation, level of economic development of the territory and wellbeing of the population, development of social infrastructure, ecological and climatic conditions, scientific researches and innovations...
2017: Zhurnal Nevrologii i Psikhiatrii Imeni S.S. Korsakova
https://www.readbyqxmd.com/read/28252249/the-isoxazole-ring-and-its-n-oxide-a-privileged-core-structure-in-neuropsychiatric-therapeutics
#6
REVIEW
George N Pairas, Fereniki Perperopoulou, Petros G Tsoungas, George Varvounis
Mental disorders are neuropsychiatric conditions that are marked by unusual or irregular thinking, feelings, or behavior, and lead to distress and/or impaired functions. Major psychiatric conditions are depression, anxiety, and psychoses of various types. Their etiopathogeneses, of a primary or secondary origin, are associated with genetic and environmental factors. They are commonly treated with psychoactive drugs (also known as psychotropics), which target serotonin, dopamine, norepinephrine, glutamate, and nuclear receptors (NRs), including retinoic acid receptor-related orphan receptors (RORs) and other receptors in the central nervous system (CNS)...
March 2, 2017: ChemMedChem
https://www.readbyqxmd.com/read/28249639/baseline-demographics-clinical-features-and-predictors-of-conversion-among-200-individuals-in-a-longitudinal-prospective-psychosis-risk-cohort
#7
G Brucato, M D Masucci, L Y Arndt, S Ben-David, T Colibazzi, C M Corcoran, A H Crumbley, F M Crump, K E Gill, D Kimhy, A Lister, S A Schobel, L H Yang, J A Lieberman, R R Girgis
BACKGROUND: DSM-5 proposes an Attenuated Psychosis Syndrome (APS) for further investigation, based upon the Attenuated Positive Symptom Syndrome (APSS) in the Structured Interview for Psychosis-Risk Syndromes (SIPS). SIPS Unusual Thought Content, Disorganized Communication and Total Disorganization scores predicted progression to psychosis in a 2015 NAPLS-2 Consortium report. We sought to independently replicate this in a large single-site high-risk cohort, and identify baseline demographic and clinical predictors beyond current APS/APSS criteria...
March 2, 2017: Psychological Medicine
https://www.readbyqxmd.com/read/28243163/drug-abuse-and-psychosis-new-insights-into-drug-induced-psychosis
#8
REVIEW
Suji Ham, Tae Kyoo Kim, Sooyoung Chung, Heh-In Im
Addictive drug use or prescribed medicine abuse can cause psychosis. Some representative symptoms frequently elicited by patients with psychosis are hallucination, anhedonia, and disrupted executive functions. These psychoses are categorized into three classifications of symptoms: positive, negative, and cognitive. The symptoms of DIP are not different from the symptoms of schizophrenia, and it is difficult to distinguish between them. Due to this ambiguity of distinction between the DIP and schizophrenia, the DIP animal model has been frequently used as the schizophrenia animal model...
February 2017: Experimental Neurobiology
https://www.readbyqxmd.com/read/28241183/association-of-gestational-weight-gain-and-maternal-body-mass-index-in-early-pregnancy-with-risk-for-nonaffective-psychosis-in-offspring
#9
Euan Mackay, Christina Dalman, Håkan Karlsson, Renee M Gardner
Importance: Prenatal exposure to famine is associated with a 2-fold risk for nonaffective psychoses. Less is known about whether maternal nutrition states during pregnancy modify offspring risk for nonaffective psychoses in offspring in well-fed populations. Objective: To determine whether gestational weight gain (GWG) during pregnancy and maternal body mass index (BMI) in early pregnancy are associated with risk for nonaffective psychoses in offspring. Design, Setting and Participants: This population-based cohort study used data from Swedish health and population registers to follow up 526 042 individuals born from January 1, 1982, through December 31, 1989, from 13 years of age until December 31, 2011...
February 22, 2017: JAMA Psychiatry
https://www.readbyqxmd.com/read/28239791/mri-study-for-the-features-of-brain-conduction-pathways-in-patients-with-an-ultra-high-risk-of-endogenous-psychoses
#10
A S Tomyshev, I S Lebedeva, T A Akhadov, M A Omel'chenko, M V Ublinskii, N A Semenova, V G Kaleda
Diffusion parameters of brain tracts (n=18) were studied in 27 men with ultra-high risk of endogenous attack-like psychoses and 27 mentally healthy men of the same age group (fractional anisotropy; and average, radial, and axial diffusion). Correlation analysis was performed between these parameters and severity of mental disorders (SOPS scale). The indexes of radial diffusion and axial diffusion were shown to change in the left anterior thalamic radiation and right posterior cingulum bundle, respectively. Our results are consistent with published data that disturbances in the frontal and temporal lobes play an important role in the pathogenesis of schizophrenia...
February 2017: Bulletin of Experimental Biology and Medicine
https://www.readbyqxmd.com/read/28236096/-cannabis-induced-disorders
#11
REVIEW
M Soyka, U Preuss, E Hoch
Use and misuse of cannabis and marihuana are frequent. About 5% of the adult population are current users but only 1.2% are dependent. The medical use of cannabis is controversial but there is some evidence for improvement of chronic pain and spasticity. The somatic toxicity of cannabis is well proven but limited and psychiatric disorders induced by cannabis are of more relevance, e.g. cognitive disorders, amotivational syndrome, psychoses and delusional disorders as well as physical and psychological dependence...
March 2017: Der Nervenarzt
https://www.readbyqxmd.com/read/28217866/zebrafish-models-in-neuropsychopharmacology-and-cns-drug-discovery
#12
REVIEW
Kanza M Khan, Adam D Collier, Darya A Meshalkina, Elana V Kysil, Sergey L Khatsko, Tatyana Kolesnikova, Yury Yu Morzherin, Jason E Warnick, Allan V Kalueff, David J Echevarria
Despite high prevalence of neuropsychiatric disorders, their etiology and molecular mechanisms remain poorly understood. The zebrafish (Danio rerio) is increasingly utilized as a powerful animal model in neuropharmacology research and in-vivo drug screening. Collectively, this makes zebrafish a useful tool for drug discovery and the identification of disordered molecular pathways. Here, we discuss zebrafish models of selected human neuropsychiatric disorders and drug-induced phenotypes. Covering a broad range of brain disorders (from anxiety and psychoses to neurodegeneration), we also summarize recent developments in zebrafish genetics and small molecule screening, which markedly enhance the disease modeling and the discovery of novel drug targets...
February 20, 2017: British Journal of Pharmacology
https://www.readbyqxmd.com/read/28199423/-outpatient-s-profile-assisted-by-the-psychiatry-residents-of-the-prof-dr-r-rossi-general-hospital-la-plata-argentina
#13
Diego Giannandrea, Julián Achilli Lucas, Lucía Saldaño, María J Barrenengoa, Mariano Dramis, Mariano Barraco, Matías González Olivi, María T Burry
OBJECTIVE: To define the profile and the treatments evolution of the outpatients assisted by the psychiatry residents of the Rossi Hospital in La Plata. METHODS: It was analyzed the period between 2005 and 2010 (six years). The variables selected included gender, age, diagnosis (according to ICD 10), duration and evolution of treatment. RESULTS: From the total number of patients (n=341), 58,7% were women (n= 200) and 41,3% men (n= 141). The most frequent diagnoses were: anxiety disorders (13,6%), depressive disorders (12,8%), schizophrenia (12,2%), other non-affective psychoses (9%) and mental retardation (8,4%)...
March 2016: Vertex: Revista Argentina de Psiquiatriá
https://www.readbyqxmd.com/read/28182195/impact-of-financial-incentives-on-alcohol-consumption-recording-in-primary-health-care-among-adults-with-schizophrenia-and-other-psychoses-a-cross-sectional-and-retrospective-cohort-study
#14
Zarnie Khadjesari, Sarah L Hardoon, Irene Petersen, Fiona L Hamilton, Irwin Nazareth
No abstract text is available yet for this article.
March 9, 2017: Alcohol and Alcoholism: International Journal of the Medical Council on Alcoholism
https://www.readbyqxmd.com/read/28179043/measurement-of-agitation-and-aggression-in-adult-and-aged-neuropsychiatric-patients-review-of-definitions-and-frequently-used-measurement-scales
#15
Ladislav Volicer, Leslie Citrome, Jan Volavka
Agitation and aggression in adult psychiatric patients with psychoses and in persons with dementia increase the burden of disease and frequently cause hospitalization. The implementation of currently available management strategies and the development of new ones is hindered by inconsistent terminology that confuses agitation with aggression. This confusion is maintained by many rating scales that fail to distinguish between these two syndromes. We review the frequently used rating scales with a particular focus on their ability to separate agitation from aggression...
February 9, 2017: CNS Spectrums
https://www.readbyqxmd.com/read/28167432/comparison-of-psychopathological-dimensions-between-major-depressive-disorder-and-schizophrenia-spectrum-disorders-focusing-on-language-affectivity-and-motor-behavior
#16
Sarah Steinau, Katharina Stegmayer, Fabian U Lang, Markus Jäger, Werner Strik, Sebastian Walther
This study tested whether patients with major depressive disorder (MDD) and schizophrenia spectrum disorders would differ in three dimensions of psychopathology (language, affectivity and motor behavior) as assessed by the Bern Psychopathology Scale (BPS) in a cohort of 58 patients with MDD and 146 patients with schizophrenia spectrum disorders. The overall estimation of severity of each of the three dimensions was rated on a seven-point Likert scale from severely inhibited to severely disinhibited. Here, more than half of the patients endorsed ratings that showed normal or mildly (dis-)inhibited behavior...
January 31, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28163499/long-term-benzodiazepine-treatment-in-patients-with-psychotic-disorders-attending-a-mental-health-service-in-rural-greece
#17
Vaios Peritogiannis, Thiresia Manthopoulou, Venetsanos Mavreas
INTRODUCTION: Long-term benzodiazepine (BZD) treatment in patients with mental disorders is widespread in clinical practice, and this is also the case of patients with schizophrenia, although the evidence is weak and BZD prescription is discouraged by guidelines and medical authorities. Data on BZD prescription are usually derived from national or regional databases whereas information on the use of BZD by patients with schizophrenia and related psychoses in general population-based samples is limited...
December 2016: Journal of Neurosciences in Rural Practice
https://www.readbyqxmd.com/read/28142106/on-the-interconnectedness-and-prognostic-value-of-visual-and-auditory-hallucinations-in-first-episode-psychosis
#18
M L Clark, F Waters, T M Vatskalis, A Jablensky
BACKGROUND: Visual hallucinations (VH) are common symptoms in schizophrenia and other psychoses. An understanding of their cross-sectional and longitudinal patterns of association with auditory hallucinations (AH) is essential for developing accurate models of hallucinatory phenomena. OBJECTIVE: This study presents the most comprehensive examination of the association between VH and AH, and its change over time, in 1303 individuals with first-episode psychosis (FEP) and 469 individuals with chronic schizophrenia...
March 2017: European Psychiatry: the Journal of the Association of European Psychiatrists
https://www.readbyqxmd.com/read/28099093/patients-with-infectious-endocarditis-and-drug-dependence-have-worse-clinical-outcomes-after-valvular-surgery
#19
Anthony Lemaire, Viktor Dombrovskiy, Siavash Saadat, George Batsides, Aziz Ghaly, Alan Spotnitz, Leonard Y Lee
BACKGROUND: Patients with infective endocarditis (IE) are at high risk for post-operative morbidity and death, which might be associated with drug abuse. The purpose of this study is to evaluate the impact of drug dependence on outcomes in patients who have IE and undergo valvular surgery (VS). PATIENTS AND METHODS: The Nationwide/National Inpatient Sample 2001-2012 was queried to select patients with IE who had elective VS using International Classification of Diseases, Ninth Revision, Clinical Modification diagnosis and procedure codes...
January 18, 2017: Surgical Infections
https://www.readbyqxmd.com/read/28073491/gray-matter-neuritic-microstructure-deficits-in-schizophrenia-and-bipolar-disorder
#20
Arash Nazeri, Benoit H Mulsant, Tarek K Rajji, Melissa L Levesque, Jon Pipitone, Laura Stefanik, Saba Shahab, Tina Roostaei, Anne L Wheeler, Sofia Chavez, Aristotle N Voineskos
BACKGROUND: Postmortem studies have demonstrated considerable dendritic pathologies among persons with schizophrenia and to some extent among those with bipolar I disorder. Modeling gray matter (GM) microstructural properties is now possible with a recently proposed diffusion-weighted magnetic resonance imaging modeling technique: neurite orientation dispersion and density imaging. This technique may bridge the gap between neuroimaging and histopathological findings. METHODS: We performed an extended series of multishell diffusion-weighted imaging and other structural imaging series using 3T magnetic resonance imaging...
December 8, 2016: Biological Psychiatry
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