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https://www.readbyqxmd.com/read/29766281/sex-and-gender-differences-in-schizophrenic-psychoses-a-critical-review
#1
Anita Riecher-Rössler, Surina Butler, Jayashri Kulkarni
Many sex and gender differences in schizophrenic psychoses have been reported, but few have been soundly replicated. A stable finding is the later age of onset in women compared to men. Gender differences in symptomatology, comorbidity, and neurocognition seem to reflect findings in the general population. There is increasing evidence for estrogens being psychoprotective in women and for hypothalamic-pituitary-gonadal dysfunction in both sexes.More methodologically sound, longitudinal, multi-domain, interdisciplinary research investigating both sex (biological) and gender (psychosocial) factors is required to better understand the different pathogenesis and etiologies of schizophrenic psychoses in women and men, thereby leading to better tailored treatments and improved outcomes...
May 16, 2018: Archives of Women's Mental Health
https://www.readbyqxmd.com/read/29759822/multivariate-relationships-between-cognition-and-brain-anatomy-across-the-psychosis-spectrum
#2
Amanda L Rodrigue, Jennifer E McDowell, Neeraj Tandon, Matcheri S Keshavan, Carol A Tamminga, Godfrey D Pearlson, John A Sweeney, Robert D Gibbons, Brett A Clementz
BACKGROUND: Cognitive and structural brain abnormalities range from mild to severe in psychosis. The relation of specific cognitive functions to specific brain structures across the psychosis spectrum is less certain. METHODS: Participants (n = 678) with bipolar, schizoaffective, or schizophrenia psychoses and healthy control subjects were recruited via the Bipolar-Schizophrenia Network for Intermediate Phenotypes. The Schizo-Bipolar Scale was used to create a psychosis continuum (from purely affective to purely nonaffective)...
March 31, 2018: Biological Psychiatry: Cognitive Neuroscience and Neuroimaging
https://www.readbyqxmd.com/read/29758999/movement-disorders-associated-with-antipsychotic-medication-in-people-with-schizophrenia-an-overview-of-cochrane-reviews-and-meta-analysis
#3
Davide Martino, Vikram Karnik, Sydney Osland, Thomas R E Barnes, Tamara M Pringsheim
Movement disorders associated with antipsychotic medications are relatively common, stigmatising, and potentially disabling. Their prevalence in people with psychosis who are prescribed second-generation antipsychotics (SGAs) is uncertain, as is their level of recognition by clinicinas. We conducted meta-analyses of randomised controlled trials included in the Cochrane Database of Systematic Reviews on schizophrenia and schizophrenia-like psychoses to estimate the prevalence of new-onset dystonia, akathisia, parkinsonism, and tremor with SGAs (amisulpride, asenapine, aripiprazole, clozapine, olanzapine, paliperidone, quetiapine, risperidone, L-sulpiride, and ziprasidone) approved in Canada and the UK, comparing them with haloperidol and chlorpromazine...
January 1, 2018: Canadian Journal of Psychiatry. Revue Canadienne de Psychiatrie
https://www.readbyqxmd.com/read/29754115/delusional-misidentifications-in-a-procrustean-bed
#4
EDITORIAL
G N Christodoulou, M Margariti, N Christodoulou
The Delusional Misidentification Syndromes (DMSs) are characterized by defective integration of the normally The Delusional Misidentification Syndromes (DMSs) are characterized by defective integration of the normally fused functions of perception and recognition. The classical sub-types are: the syndromes of Capgras, Fregoli,Intermetamorphosis (mentioned in 3) and Subjective doubles. These syndromes occur in a clear sensorium and shouldbe differentiated from the banal transient misidentifications occurring in confusional states and in mania and from thenon-delusional misidentifications (e...
January 2018: Psychiatrikē, Psychiatriki
https://www.readbyqxmd.com/read/29736086/response-to-issues-concerning-the-article-treatment-compliance-and-noncompliance-in-psychoses
#5
K Nagaraja Rao
No abstract text is available yet for this article.
January 2018: Indian Journal of Psychiatry
https://www.readbyqxmd.com/read/29726021/etiologies-predictors-and-economic-impact-of-readmission-within-one-month-among-patients-with-takotsubo-cardiomyopathy
#6
Mahek Shah, Pradhum Ram, Kevin Bryan U Lo, Natee Sirinvaravong, Brijesh Patel, Byomesh Tripathi, Shantanu Patil, Vincent M Figueredo
BACKGROUND: Limited data exists on readmission among patients with takotsubo cardiomyopathy [TC], a commonly reversible cause of heart failure. We sought to identify etiologies and predictors for readmission among TC patients. METHODS: We queried the National Readmissions Database for 2013-2014 to identify patients with primary admission for TC using ICD-9CM code 429.83. Patients who were readmitted to the hospital within 1-month post-discharge were further evaluated to identify etiologies, predictors and the resultant economic burden of readmission...
May 3, 2018: Clinical Cardiology
https://www.readbyqxmd.com/read/29723811/increased-mortality-among-people-with-schizophrenia-and-other-non-affective-psychotic-disorders-in-the-community-a-systematic-review-and-meta-analysis
#7
REVIEW
Padraig Oakley, Steve Kisely, Amanda Baxter, Meredith Harris, Jocelyne Desoe, Alyona Dziouba, Dan Siskind
INTRODUCTION: There is increasing evidence of excess mortality in schizophrenia but less information on other non-affective psychoses. We therefore generated standardised mortality ratios (SMRs) for community-dwelling people with schizophrenia and other non-affective psychoses, relative to the general population, and examined changes to the SMR over time. METHODS: We conducted a systematic review in which Pubmed, CINAHL, EMBASE, Google Scholar and PsycINFO were searched for publications that reported SMRs for all-cause mortality among community-dwelling people with schizophrenia and psychotic disorders...
April 26, 2018: Journal of Psychiatric Research
https://www.readbyqxmd.com/read/29720114/adverse-obstetric-and-neonatal-outcomes-complicated-by-psychosis-among-pregnant-women-in-the-united-states
#8
Qiu-Yue Zhong, Bizu Gelaye, Gregory L Fricchione, Paul Avillach, Elizabeth W Karlson, Michelle A Williams
BACKGROUND: Adverse obstetric and neonatal outcomes among women with psychosis, particularly affective psychosis, has rarely been studied at the population level. We aimed to assess the risk of adverse obstetric and neonatal outcomes among women with psychosis (schizophrenia, affective psychosis, and other psychoses). METHODS: From the 2007 - 2012 National (Nationwide) Inpatient Sample, 23,507,597 delivery hospitalizations were identified. From the same hospitalization, International Classification of Diseases diagnosis codes were used to identify maternal psychosis and outcomes...
May 2, 2018: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/29717522/brain-morphologic-changes-in-early-stages-of-psychosis-implications-for-clinical-application-and-early-intervention
#9
Tsutomu Takahashi, Michio Suzuki
To date, a large number of magnetic resonance imaging (MRI) studies have been conducted in schizophrenia, which generally demonstrate gray matter reduction predominantly in the frontal and temporo-limbic regions, as well as gross brain abnormalities (e.g., a deviated sulcogyral pattern). Although the causes as well as timing and course of these findings remain elusive, these morphologic changes (especially gross brain abnormalities and medial temporal lobe atrophy) are likely present at illness onset, possibly reflecting early neurodevelopmental abnormalities...
May 1, 2018: Psychiatry and Clinical Neurosciences
https://www.readbyqxmd.com/read/29692865/utilization-of-psychiatric-rehabilitation-services-and-influencing-factors-among-people-with-psychotic-disorders-in-rural-communities-of-guangxi-china
#10
Hongye Luo, Edward B McNeil, Qiming Feng, Hongheng Li, Qiang Chen, Xianjing Qin, Jun Feng, Sawitri Assanangkornchai
Objectives: To identify the rate and predictors of utilization of rehabilitation services among people with psychotic disorders in rural communities of Guangxi. Study design: A cross-sectional survey was conducted among individuals with schizophrenia or other psychoses (severe mental disorder, ICD10: F20-F29), aged over 15 years, and their care-givers in Guangxi, China. Trained village doctors located individuals known to them and suspected as having schizophrenia or other psychoses within the target areas and recruited them into the study...
2018: International Journal of Mental Health Systems
https://www.readbyqxmd.com/read/29680513/the-relationship-between-illicit-amphetamine-use-and-psychiatric-symptom-profiles-in-schizophrenia-and-affective-psychoses
#11
Alexandra Voce, Rebecca McKetin, Richard Burns, David Castle, Bianca Calabria
This study examines whether illicit amphetamine use is associated with differences in the prevalence of specific psychiatric symptoms in a community sample of individuals diagnosed with schizophrenia or affective psychotic disorders. Data was drawn from the Australian Survey of High Impact Psychosis. The Diagnostic Interview for Psychosis was used to measure substance use and psychiatric symptoms. Participants had used amphetamine within their lifetime and had an ICD-10 diagnosis of schizophrenia (n = 347) or an affective psychotic disorder (n = 289)...
April 5, 2018: Psychiatry Research
https://www.readbyqxmd.com/read/29674982/delusional-themes-across-affective-and-non-affective-psychoses
#12
Angelo Picardi, Laura Fonzi, Mauro Pallagrosi, Antonella Gigantesco, Massimo Biondi
The current debate about the diagnostic significance of delusion revolves around two positions. The neurocognitive position conceives delusion as a non-specific, though polymorphic, symptom. The psychopathological position views features of delusion such as content and structure as having meaningful connections with diagnostic entities. This study aims at contributing to this debate by examining the association between delusional themes and diagnosis in a sample of 830 adult psychotic patients. All diagnoses were made by experienced psychiatrists according to DSM-IV or ICD-10 criteria, and in 348 patients were established with the SCID-I...
2018: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/29648618/inflammation-in-schizophrenia-pathogenetic-aspects-and-therapeutic-considerations
#13
Norbert Müller
This paper discusses the current evidence from animal and human studies for a central role of inflammation in schizophrenia. In animal models, pre- or perinatal elicitation of the immune response may increase immune reactivity throughout life, and similar findings have been described in humans. Levels of pro-inflammatory markers, such as cytokines, have been found to be increased in the blood and cerebrospinal fluid of patients with schizophrenia. Numerous epidemiological and clinical studies have provided evidence that various infectious agents are risk factors for schizophrenia and other psychoses...
April 10, 2018: Schizophrenia Bulletin
https://www.readbyqxmd.com/read/29625792/gray-matter-differences-between-affective-and-non-affective-first-episode-psychosis-a-review-of-magnetic-resonance-imaging-studies
#14
REVIEW
A Calvo, G Delvecchio, A C Altamura, J C Soares, P Brambilla
BACKGROUND: Non-affective and affective psychoses are very common mental disorders. However, their neurobiological underpinnings are still poorly understood. Therefore, the goal of the present review was to evaluate structural Magnetic Resonance Imaging (MRI) studies exploring brain deficits in both non-affective (NA-FEP) and affective first episode psychosis (A-FEP). METHODS: A bibliographic search on PUBMED of all MRI studies exploring gray matter (GM) differences between NA-FEP and A-FEP was conducted...
March 17, 2018: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29622048/systemic-inflammation-and-intelligence-in-early-adulthood-and-subsequent-risk-of-schizophrenia-and-other-non-affective-psychoses-a-longitudinal-cohort-and-co-relative-study
#15
Nils Kappelmann, Golam M Khandaker, Henrik Dal, Jan Stochl, Kyriaki Kosidou, Peter B Jones, Christina Dalman, Håkan Karlsson
BACKGROUND: Schizophrenia is associated with impaired neurodevelopment as indexed by lower premorbid IQ. We examined associations between erythrocyte sedimentation rate (ESR), a marker of low-grade systemic inflammation, IQ, and subsequent schizophrenia and other non-affective psychoses (ONAP) to elucidate the role of neurodevelopment and inflammation in the pathogenesis of psychosis. METHODS: Population-based data on ESR and IQ from 638 213 Swedish men assessed during military conscription between 1969 and 1983 were linked to National Hospital Discharge Register for hospitalisation with schizophrenia and ONAP...
April 6, 2018: Psychological Medicine
https://www.readbyqxmd.com/read/29617531/consanguineous-marriage-and-the-psychopathology-of-progeny-a-population-wide-data-linkage-study
#16
Aideen Maguire, Foteini Tseliou, Dermot O'Reilly
Importance: Approximately 1 in 10 children worldwide are born to consanguineous parents. The literature on consanguinity and mental health of progeny is scarce despite the fact that many of the factors associated with consanguineous unions are also associated with mental health. Objective: To investigate if children of consanguineous parents are at increased risk of common mood disorders or psychoses. Design, Setting, and Participants: This investigation was a retrospective population-wide cohort study of all individuals born in Northern Ireland between January 1, 1971, and December 31, 1986, derived from the Child Health System data set and linked to nationwide administrative data sources on prescription medication and death records...
April 4, 2018: JAMA Psychiatry
https://www.readbyqxmd.com/read/29609990/behavior-problems-inventory-bpi-psychometric-characteristics-of-an-instrument-for-routine-assessment-of-persons-with-psychoses-and-related-disorders
#17
Antonio J Vázquez Morejón, Raquel Vázquez-Morejón, Gloria Bellido Zanin
This study explores the psychometric characteristics of the Behavior Problems Inventory (BPI), an instrument for routine clinical assessment of behavior problems in outpatients with psychosis based on information provided by key family informants. Six hundred and twenty-one patients diagnosed with psychosis and bipolar affective disorder (ICD-10 F20-F31) attended at Community Mental Health Units were evaluated in routine reviews using the BPI and the Social Functioning Scale (SFS). Twenty-five subjects were simultaneously administered the Social Behavior Schedule (SBS) and 28 were again administered the BPI eight weeks later...
March 22, 2018: Psychiatry Research
https://www.readbyqxmd.com/read/29606183/desperately-seeking-outcomes-quantifying-the-effectiveness-of-community-mental-healthcare-using-health-of-the-nation-outcome-scales
#18
Richard Laugharne, Scott Eaves, Alin Mascas, Kiki Psatha, Gill Dinnis, Jonathan Trower, Rohit Shankar
BACKGROUND: Community mental health services in the UK have struggled to measure the clinical effectiveness of their services.AimsTo measure clinical outcomes for different diagnostic clusters. METHOD: Clinicians measure the clinical status of patients by the Health of the Nation Outcome Scales (HoNOS), and HoNOS scores should be recorded annually after treatment. Clinical outcomes were measured by changes in HoNOS for diagnostic clusters. RESULTS: In two time periods (2014 and 2016), the health of patients with mild to moderate common mental disorders deteriorated after intervention...
May 2018: BJPsych Open
https://www.readbyqxmd.com/read/29605160/sexually-dimorphic-subcortical-brain-volumes-in-emerging-psychosis
#19
Laura Egloff, Claudia Lenz, Erich Studerus, Fabienne Harrisberger, Renata Smieskova, André Schmidt, Christian Huber, Andor Simon, Undine E Lang, Anita Riecher-Rössler, Stefan Borgwardt
BACKGROUND: In schizophrenic psychoses, the normal sexual dimorphism of the brain has been shown to be disrupted or even reversed. Little is known, however, at what time point in emerging psychosis this occurs. We have therefore examined, if these alterations are already present in the at-risk mental state (ARMS) for psychosis and in first episode psychosis (FEP) patients. METHODS: Data from 65 ARMS (48 (73.8%) male; age=25.1±6.32) and 50 FEP (37 (74%) male; age=27±6...
March 28, 2018: Schizophrenia Research
https://www.readbyqxmd.com/read/29581153/aicar-prevents-acute-olanzapine-induced-disturbances-in-glucose-homeostasis
#20
Natasha D Bush, Logan K Townsend, David C Wright
Olanzapine (OLZ) is an antipsychotic drug used in the treatment of schizophrenia. While effective in reducing psychoses, OLZ causes acute increases in blood glucose. The acute effects of OLZ on hyperglycaemia are likely caused by reductions in insulin secretion, insulin resistance and increased hepatic glucose production. 5'AMP-activated protein kinase (AMPK) is an energy sensor activated during exercise that can increase insulin sensitivity and insulin-independent glucose uptake in muscle. 5-aminoimidazole-4-carboxamide ribonucleoside (AICAR) is a pharmacological agent that, among other effects, can activate AMPK in vivo...
March 26, 2018: Journal of Pharmacology and Experimental Therapeutics
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