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https://www.readbyqxmd.com/read/29141491/association-of-psychosis-affective-disorders-and-diseases-affecting-the-immune-system
#1
Jeanette Brun Larsen, Valentina Cabral Iversen, Solveig Klæbo Reitan
Purpose of the article: There are indications of altered immune activity in depressed and psychotic patients compared to healthy controls in several studies. To explore the clinical importance of this phenomenon we examined the relation between different disorders affecting the immune system and psychoses and depression, respectively. MATERIALS AND METHODS: A total of 276 patients consecutively admitted to a psychiatric acute ward were included in the study. Of these 41 patients fulfilled the criteria for ICD-10 F20-29 (psychotic) diagnosis and 157 patients a F30-39 (affective) diagnosis...
November 16, 2017: Nordic Journal of Psychiatry
https://www.readbyqxmd.com/read/29130372/-motility-psychoses-by-erik-str%C3%A3-mgren-1940
#2
German E Berrios, Johan Schioldann
The motility psychoses are a group of acute psychiatric conditions characterized by salient disorders of movement (increased, decreased and disorganized), psychotic experiences, confusion and good prognosis. The debate on whether they are just atypical forms of schizophrenia or manic-depressive insanity or constitute an independent group of psychoses has not yet been settled. Erik Strömgren's classical chapter deals with the history and clinical aspects of the motility psychoses. Based on a historical analysis and an empirical study of a patient cohort, the author draws conclusions on the nature of this clinical group that has stood the test of time well...
December 2017: History of Psychiatry
https://www.readbyqxmd.com/read/29110959/-taxation-of-traditional-rums-in-french-overseas-territories-and-public-health-the-example-of-reunion-island
#3
D Mété
BACKGROUND: France has a complex system for the taxation of alcoholic beverages. In the French overseas territories (FOT), the system includes little-known specificities whose purpose is to preserve the sugar-cane-rum sector, a pillar for the weak economies in these territories. Taxes are reduced for traditional rums produced and sold locally. This favors the marketing of alcoholic spirits at low prices. In metropolitan France, on the contrary, spirits are heavily taxed drinks and their share in consumption is minor...
November 2017: Revue D'épidémiologie et de Santé Publique
https://www.readbyqxmd.com/read/29093939/china-s-national-comprehensive-management-pilot-project-for-mental-health
#4
Wufang Zhang, Ning Ma
The National Continuing Management and Intervention Programme for Psychoses, also known as the 686 Programme, was launched in China in 2004, marking a shift to a hospital-and-community collaborative model of care for patients with psychoses. An updated programme, the National Comprehensive Management Pilot Project for Mental Health, was launched in 2015 with the cooperation of six government ministries and bodies, including the China Disabled Persons Federation. Mechanisms for multi-sector cooperation in mental health services are being put in place in China...
May 2017: BJPsych Int
https://www.readbyqxmd.com/read/29074330/motor-dysfunction-as-an-intermediate-phenotype-across-schizophrenia-and-other-psychotic-disorders-progress-and-perspectives
#5
Dusan Hirjak, Katharina M Kubera, Philipp A Thomann, Robert C Wolf
Primary motor abnormalities (PMA), as found in patients with schizophrenia, are quantitatively and qualitatively distinct markers of motor system abnormalities. PMA have been often referred to phenomena that are present across schizophrenia-spectrum disorders. A dysfunction of frontoparietal and subcortical networks has been proposed as core pathophysiological mechanism underlying the expression of PMA. However, it is unclear at present if such mechanisms are a common within schizophrenia and other psychotic disorders...
October 23, 2017: Schizophrenia Research
https://www.readbyqxmd.com/read/29069978/assessment-of-de-novo-copy-number-variations-in-italian-patients-with-schizophrenia-detection-of-putative-mutations-involving-regulatory-enhancer-elements
#6
Giulio Piluso, Palmiero Monteleone, Silvana Galderisi, Teresa Giugliano, Alessandro Bertolino, Paola Rocca, Alessandro Rossi, Armida Mucci, Eugenio Aguglia, Ileana Andriola, Antonello Bellomo, Anna Comparelli, Francesco Gambi, Andrea Fagiolini, Carlo Marchesi, Rita Roncone, Emilio Sacchetti, Paolo Santonastaso, Alberto Siracusano, Paolo Stratta, Alfonso Tortorella, Luca Steardo, Paola Bucci, Vincenzo Nigro, Mario Maj
Objectives Variants appearing de novo in genes regulating key neurodevelopmental processes and/or in noncoding cis-regulatory elements (CREs), as enhancers, may increase the risk for schizophrenia. However, CREs involvement in schizophrenia needs to be explored more deeply. Methods We investigated de novo copy number variations (CNVs) in the whole genomic DNA obtained from 46 family trios of schizophrenia probands by using the Enhancer Chip, a customized array CGH able to investigate the whole genome with a 300Kb resolution, specific disease loci at a tenfold higher resolution, and that was highly enriched in probes in more than 1...
October 26, 2017: World Journal of Biological Psychiatry
https://www.readbyqxmd.com/read/29056371/preventive-service-use-among-people-with-and-without-serious-mental-illnesses
#7
Bobbi Jo H Yarborough, Nancy A Perrin, Scott P Stumbo, John Muench, Carla A Green
INTRODUCTION: People with serious mental illnesses experience excess morbidity and premature mortality resulting from preventable conditions. The goal was to examine disparities in preventive care that might account for poor health outcomes. METHODS: In this retrospective cohort study, adults (N=803,276) served by Kaiser Permanente Northwest and federally qualified health centers/safety-net community health clinics were categorized into five groups: schizophrenia spectrum disorders, bipolar disorders/affective psychoses, anxiety disorders, nonpsychotic unipolar depression, and reference groups with no evidence of these specific mental illnesses...
October 11, 2017: American Journal of Preventive Medicine
https://www.readbyqxmd.com/read/29046989/epilepsy-and-psychiatric-comorbidities-drug-selection
#8
REVIEW
Marco Mula
Purpose of review The pharmacological treatment of patients with epilepsy and psychiatric comorbidities may sometimes represent a therapeutic challenge. This review is focused on the pharmacological management of patients with epilepsy and psychiatric problems in terms of rationalization of the antiepileptic drug (AED) treatment and the pharmacological management of the most clinically relevant psychiatric comorbidities, namely mood and anxiety disorders, psychoses, and attention deficit hyperactivity disorder (ADHD)...
October 19, 2017: Current Treatment Options in Neurology
https://www.readbyqxmd.com/read/29043155/catatonia-as-a-putative-nosological-entity-a-historical-sketch
#9
REVIEW
Gábor Gazdag, Rozalia Takács, Gabor S Ungvari
Kahlbaum was the first to propose catatonia as a separate disease following the example of general paresis of the insane, which served as a model for establishing a nosological entity. However, Kahlbaum was uncertain about the nosological position of catatonia and considered it a syndrome, or "a temporary stage or a part of a complex picture of various disease forms". Until recently, the issue of catatonia as a separate diagnostic category was not entertained, mainly due to a misinterpretation of Kraepelin's influential views on catatonia as a subtype of schizophrenia...
September 22, 2017: World Journal of Psychiatry
https://www.readbyqxmd.com/read/29041995/reproducibility-of-cognitive-profiles-in-psychosis-using-cluster-analysis
#10
Kathryn E Lewandowski, Justin T Baker, Julie M McCarthy, Lesley A Norris, Dost Öngür
OBJECTIVES: Cognitive dysfunction is a core symptom dimension that cuts across the psychoses. Recent findings support classification of patients along the cognitive dimension using cluster analysis; however, data-derived groupings may be highly determined by sampling characteristics and the measures used to derive the clusters, and so their interpretability must be established. We examined cognitive clusters in a cross-diagnostic sample of patients with psychosis and associations with clinical and functional outcomes...
October 18, 2017: Journal of the International Neuropsychological Society: JINS
https://www.readbyqxmd.com/read/29038946/cognitive-and-behavioral-disorders-in-parkinson-s-disease-an-update-ii-behavioral-disorders
#11
Luigi Trojano, Costanza Papagno
Patients with Parkinson's disease (PD) can experience several behavioral symptoms, such as apathy, agitation, hypersexuality, stereotypic movements, pathological gambling, abuse of antiparkinsonian drugs, and REM sleep behavioral disorders. Psychoses and hallucinations, depression and anxiety disorders, and difficulties in recognizing and experiencing emotions also impair behavior and can cause severe psychosocial problems in patients with PD. Symptoms can be present since early stages of the disease, sometimes even before the appearance of classical motor symptoms, likely in relation to dopamine depletion in basal ganglia and/or to dysfunctions of other neurotrasmitter systems, and others can develop later, in some cases in relation to dopaminergic treatment...
October 16, 2017: Neurological Sciences
https://www.readbyqxmd.com/read/29034588/clinical-and-demographic-differences-between-patients-with-manic-depressive-and-schizophrenia-spectrum-psychoses-presenting-to-early-intervention-services-in-london
#12
Adisha Kapila, Helen L Fisher, Sonia Johnson, Barnaby Major, Nikola Rahaman, John Joyce, Nick Chamberlain-Kent, Jo Lawrence, Allan H Young, James M Stone
AIM: To investigate the relationship between the presenting clinical and demographic characteristics in first-episode psychosis (FEP) patients with their clinical diagnostic grouping 1 year later. METHODS: Data from 1014 first-presentation psychosis patients from seven London-based Early Intervention Services were extracted from the MiData audit database. Associations between clinical and demographic measures at presentation and clinical diagnosis made at 1 year were assessed with analysis of variance (ANOVA) and Chi-square tests...
October 15, 2017: Early Intervention in Psychiatry
https://www.readbyqxmd.com/read/29017620/familial-aggregation-of-matrics-consensus-cognitive-battery-scores-in-a-large-sample-of-outpatients-with-schizophrenia-and-their-unaffected-relatives
#13
A Mucci, S Galderisi, M F Green, K Nuechterlein, P Rucci, D Gibertoni, A Rossi, P Rocca, A Bertolino, P Bucci, G Hellemann, M Spisto, D Palumbo, E Aguglia, G Amodeo, M Amore, A Bellomo, R Brugnoli, B Carpiniello, L Dell'Osso, F Di Fabio, M di Giannantonio, G Di Lorenzo, C Marchesi, P Monteleone, C Montemagni, L Oldani, R Romano, R Roncone, P Stratta, E Tenconi, A Vita, P Zeppegno, M Maj
BACKGROUND: The increased use of the MATRICS Consensus Cognitive Battery (MCCB) to investigate cognitive dysfunctions in schizophrenia fostered interest in its sensitivity in the context of family studies. As various measures of the same cognitive domains may have different power to distinguish between unaffected relatives of patients and controls, the relative sensitivity of MCCB tests for relative-control differences has to be established. We compared MCCB scores of 852 outpatients with schizophrenia (SCZ) with those of 342 unaffected relatives (REL) and a normative Italian sample of 774 healthy subjects (HCS)...
October 11, 2017: Psychological Medicine
https://www.readbyqxmd.com/read/29017334/brexpiprazole-a-new-leaf-on-the-partial-dopamine-agonist-branch
#14
Judy Hope, David Castle, Nicholas A Keks
OBJECTIVES: Brexpiprazole is a new dopamine partial agonist antipsychotic in the same class as aripiprazole. This paper will briefly review brexpiprazole and compare it with aripiprazole. CONCLUSIONS: Brexpiprazole and aripiprazole are both partial agonists at dopamine D2, and serotonin 5-HT1A and antagonists at serotonin 5-HT2A and noradrenergic α1B receptors. However, the two drugs are significantly different in potencies at various receptors; neurochemical profiles predict that brexpiprazole may be comparable with aripiprazole in its antipsychotic efficacy but may cause less akathisia, extrapyramidal side effects (EPS) and activation...
October 1, 2017: Australasian Psychiatry: Bulletin of Royal Australian and New Zealand College of Psychiatrists
https://www.readbyqxmd.com/read/28979994/factors-associated-with-30-day-readmission-after-primary-total-hip-arthroplasty-analysis-of-514%C3%A2-455-procedures-in-the-uk-national-health-service
#15
Adam M Ali, Mark D Loeffler, Paul Aylin, Alex Bottle
Importance: Thirty-day readmission to hospital after total hip arthroplasty (THA) has significant direct costs and is used as a marker of hospital performance. All-cause readmission is the only metric in current use, and risk factors for surgical readmission and those resulting in return to theater (RTT) are poorly understood. Objective: To determine whether patient-related predictors of all-cause, surgical, and RTT readmission after THA differ and which predictors are most significant...
October 4, 2017: JAMA Surgery
https://www.readbyqxmd.com/read/28966601/the-lacanian-concept-of-paranoia-an-historical-perspective
#16
Thomas Lepoutre, Manoel L Madeira, Nicolas Guerin
This article seeks to reopen a major question raised by the Lacanian nosology of the psychoses, by looking closely at Lacan's formulations of what he never ceased referring to as "paranoia". While almost all classification systems of modern psychiatry, such as the ICD-10 and the DSM-5, have abandoned the specific category of paranoia, Lacan always viewed paranoia as a major category of "functional psychosis". He held that paranoia was a qualitatively different disorder than schizophrenia, and considered it to be the principal or exemplary form of psychosis...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28961352/therapeutic-alliance-in-psychological-therapy-for-people-with-schizophrenia-and-related-psychoses-a-systematic-review
#17
Lucy Shattock, Katherine Berry, Amy Degnan, Dawn Edge
Therapeutic alliance is a key predictor of therapy outcomes. Alliance may be particularly pertinent for people with schizophrenia as this group often have a history of interpersonal trauma and relationship difficulties including difficult relationships with mental health staff. This review aimed to determine (a) the quality of therapeutic alliance between people with schizophrenia and their therapists; (b) whether alliance predicts therapeutic outcomes; and (c) variables associated with alliance. Databases were searched from inception up to April 2015...
September 29, 2017: Clinical Psychology & Psychotherapy
https://www.readbyqxmd.com/read/28959434/naltrexone-efficacy-in-treating-alcohol-use-disorder-in-individuals-with-comorbid-psychosis-a-systematic-review
#18
REVIEW
Martyna Sawicka, Derek K Tracy
BACKGROUND: Psychotic illnesses, such as schizophrenia, are typically enduring and disabling conditions, impacting individual, family, and societal outcomes. Individuals with these face greater vulnerabilities in developing alcohol-use disorder (AUD). Furthermore, the nature of psychoses, often manifesting with paranoia, cognitive impairment, a lack of insight, sub-optimal treatment adherence, and stigma from others, means that they can pose unique treatment challenges when these two conditions comorbidly occur...
September 2017: Therapeutic Advances in Psychopharmacology
https://www.readbyqxmd.com/read/28949308/mental-health-in-domesticated-immigrant-population-a-systematic-review
#19
Boris Ilić, Vesna Švab, Biserka Sedić, Irena Kovačević, Adriano Friganović, Ena Jurić
BACKGROUND: Migration is a process during which a person moves from one cultural setting to another in order to settle for a longer period of time or permanently. The number of immigrants in the world has more than doubled since 1975, with majority of migrants living in Europe today. Migration is now being increasingly recognized as a risk factor for multiple mental-health related issues, such as schizophrenia, psychosis, anxiety disorders and others. AIM: The aim of this study was to collect, systematically review and analyze relevant articles pertaining to the mental health of second-or-higher generations of domesticated immigrant population, as well as to determine common socio-cultural predisposition factors leading to the development of mental illness among the mentioned population...
September 2017: Psychiatria Danubina
https://www.readbyqxmd.com/read/28941779/historical-and-conceptual-aspects-of-motor-disorders-in-the-psychoses
#20
German E Berrios, Ivana S Marková
Historical epistemology is a useful method to understand the longitudinal construction of the movement disorders in psychiatry. Four periods can be identified in such a process. The first, extending from Classical times to the work of Griesinger, included disorders such as catalepsy, crocidism, epilepsy and paralysis. The second period, stretching from Griesinger to Kahlbaum, concentrated on the study of melancholia attonita, stupor and catatonia. The third period, covering the time from Kahlbaum to WWI, witnessed important conceptual shifts such as: the transformation of madness into psychoses; the redefinition of movement and motility in psychiatry; the appearance of self-contained syndromes as dyskinesias, tics, akathisia, complex disorders like the cases of encephalitis lethargica, etc...
September 20, 2017: Schizophrenia Research
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