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"Economic evaluation"

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https://www.readbyqxmd.com/read/28822113/economic-evaluation-of-interventions-for-children-with-neurodevelopmental-disorders-opportunities-and-challenges
#1
Ramesh Lamsal, Jennifer D Zwicker
Economic evaluation is a tool used to inform decision makers on the efficiency of comparative healthcare interventions and inform resource allocation decisions. There is a growing need for the use of economic evaluations to assess the value of interventions for children with neurodevelopmental disorders (NDDs), a population that has increasing demands for healthcare services. Unfortunately, few evaluations have been conducted to date, perhaps stemming from challenges in applying existing economic evaluation methodologies in this heterogeneous population...
August 18, 2017: Applied Health Economics and Health Policy
https://www.readbyqxmd.com/read/28821527/systematic-review-of-economic-analyses-in-patient-safety-a-protocol-designed-to-measure-development-in-the-scope-and-quality-of-evidence
#2
Alexander W Carter, Rishi Mandavia, Erik Mayer, Joachim Marti, Elias Mossialos, Ara Darzi
INTRODUCTION: Recent avoidable failures in patient care highlight the ongoing need for evidence to support improvements in patient safety. According to the most recent reviews, there is a dearth of economic evidence related to patient safety. These reviews characterise an evidence gap in terms of the scope and quality of evidence available to support resource allocation decisions. This protocol is designed to update and improve on the reviews previously conducted to determine the extent of methodological progress in economic analyses in patient safety...
August 18, 2017: BMJ Open
https://www.readbyqxmd.com/read/28821512/protocol-for-an-economic-evaluation-of-the-randomised-controlled-trial-of-culprit-lesion-only-pci-versus-immediate-multivessel-pci-in-acute-myocardial-infarction-complicated-by-cardiogenic-shock-culprit-shock-trial
#3
Zahidul Quayyum, Andrew Briggs, Jose Robles-Zurita, Keith Oldroyd, Uwe Zeymer, Steffen Desch, Suzanne de Waha, Holger Thiele
INTRODUCTION: Emergency percutaneous coronary intervention (PCI) of the culprit lesion for patients with acute myocardial infarctions is an accepted practice. A majority of patients present with multivessel disease with additional relevant stenoses apart from the culprit lesion. In haemodynamically stable patients, there is increasing evidence from randomised trials to support the practice of immediate complete revascularisation. However, in the presence of cardiogenic shock, the optimal management strategy for additional non-culprit lesions is unknown...
August 18, 2017: BMJ Open
https://www.readbyqxmd.com/read/28809389/cost-effectiveness-analysis-of-telephone-based-support-for-the-management-of-pressure-ulcers-in-people-with-spinal-cord-injury-in-india-and-bangladesh
#4
M Arora, L A Harvey, J V Glinsky, H S Chhabra, M S Hossain, N Arumugam, P K Bedi, I D Cameron, A J Hayes
OBJECTIVE: To determine from a societal perspective the cost-effectiveness and cost-utility of telephone-based support for management of pressure ulcers. STUDY DESIGN: Cost-effectiveness and cost-utility analysis of a randomised clinical trial. SETTING: Tertiary centre in India and Bangladesh. METHODS: An economic evaluation was conducted alongside a randomised clinical trial comparing 12 weeks of telephone-based support (intervention group) with usual care (control group)...
August 15, 2017: Spinal Cord
https://www.readbyqxmd.com/read/28806786/an-economic-evaluation-of-vector-control-in-the-age-of-a-dengue-vaccine
#5
Christopher Fitzpatrick, Alexander Haines, Mathieu Bangert, Andrew Farlow, Janet Hemingway, Raman Velayudhan
INTRODUCTION: Dengue is a rapidly emerging vector-borne Neglected Tropical Disease, with a 30-fold increase in the number of cases reported since 1960. The economic cost of the illness is measured in the billions of dollars annually. Environmental change and unplanned urbanization are conspiring to raise the health and economic cost even further beyond the reach of health systems and households. The health-sector response has depended in large part on control of the Aedes aegypti and Ae...
August 14, 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28806728/costing-evidence-for-health-care-decision-making-in-austria-a-systematic-review
#6
Susanne Mayer, Noemi Kiss, Agata Łaszewska, Judit Simon
BACKGROUND: With rising healthcare costs comes an increasing demand for evidence-informed resource allocation using economic evaluations worldwide. Furthermore, standardization of costing and reporting methods both at international and national levels are imperative to make economic evaluations a valid tool for decision-making. The aim of this review is to assess the availability and consistency of costing evidence that could be used for decision-making in Austria. It describes systematically the current economic evaluation and costing studies landscape focusing on the applied costing methods and their reporting standards...
2017: PloS One
https://www.readbyqxmd.com/read/28801762/does-the-use-of-the-proportional-shortfall-help-align-the-prioritisation-of-health-services-with-public-preferences
#7
Jeff Richardson, Angelo Iezzi, Aimee Maxwell, Gang Chen
It has been proposed that equity may be included in the economic evaluation of health services using the 'proportional shortfall' (PS)-the proportion of a person's QALY expectation that they would lose because of an illness. The present paper reports the results of a population survey designed to test whether PS helped to explain people's preferences for health services and whether it did this better than the absolute shortfall or the equity related variables that PS seeks to replace. Survey respondents were asked to allocate 100 votes between 13 scenarios and a standard scenario...
August 11, 2017: European Journal of Health Economics: HEPAC: Health Economics in Prevention and Care
https://www.readbyqxmd.com/read/28801433/developing-core-economic-outcome-sets-for-asthma-studies-a-protocol-for-a-systematic-review
#8
Natalia Hounsome, Deborah Fitzsimmons, Ceri Phillips, Anita Patel
INTRODUCTION: Core outcome sets are standardised lists of outcomes, which should be measured and reported in all clinical studies of a specific condition. This study aims to develop core outcome sets for economic evaluations in asthma studies. Economic outcomes include items such as costs, resource use or quality-adjusted life years. The starting point in developing core outcome sets will be conducting a systematic literature review to establish a preliminary list of reporting items to be considered for inclusion in the core outcome set...
August 11, 2017: BMJ Open
https://www.readbyqxmd.com/read/28801235/cost-effectiveness-of-a-proactive-primary-care-program-for-frail-older-people-a-cluster-randomized-controlled-trial
#9
Nienke Bleijenberg, Irene Drubbel, Rabin Ej Neslo, Marieke J Schuurmans, Valerie H Ten Dam, Mattijs E Numans, G Ardine de Wit, Niek J de Wit
BACKGROUND: A proactive integrated approach has shown to preserve daily functioning among older people in the community. The aim is to determine the cost-effectiveness of a proactive integrated primary care program. METHODS: Economic evaluation embedded in a single-blind, 3-armed, cluster-randomized controlled trial with 12 months' follow-up in 39 general practices in the Netherlands. General practices were randomized to one of 3 trial arms: (1) an electronic frailty screening instrument using routine medical record data followed by standard general practitioner (GP) care; (2) this screening instrument followed by a nurse-led care program; or (3) usual care...
August 8, 2017: Journal of the American Medical Directors Association
https://www.readbyqxmd.com/read/28797940/values-for-the-icecap-supportive-care-measure-icecap-scm-for-use-in-economic-evaluation-at-end-of-life
#10
Elisabeth Huynh, Joanna Coast, John Rose, Philip Kinghorn, Terry Flynn
End of life care may have elements of value that go beyond health. A generic measure of the benefits of end of life care could be helpful to decision makers. Such a measure, based on the capability approach, has recently been developed: the ICECAP Supportive Care Measure. This paper reports the first valuation exercise for that measure, with data from 6020 individuals collected from an on-line general population panel during June 2013. Individuals were asked to complete a stated choice experiment that combined best-worst scaling and a standard discrete choice experiment...
July 21, 2017: Social Science & Medicine
https://www.readbyqxmd.com/read/28797288/measuring-the-health-related-quality-of-life-of-children-with-impaired-mobility-examining-correlation-and-agreement-between-children-and-parent-proxies
#11
Nathan Bray, Jane Noyes, Nigel Harris, Rhiannon Tudor Edwards
OBJECTIVE: The objective of this research project was to evaluate the validity of proxy health-related quality of life measures in the context of paediatric mobility impairment. Accurate health-related quality of life data is essential for quality-adjusted life year calculation; a key outcome in economic evaluation. Thirteen child-parent dyads (13 children with mobility impairments, 13 parent proxies) were asked to complete a range of outcome measures (EQ-5D-Y, VAS and HUI2/3) relating to the child's health...
August 10, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28795682/effects-of-antenatal-diet-and-physical-activity-on-maternal-and-fetal-outcomes-individual-patient-data-meta-analysis-and-health-economic-evaluation
#12
Ewelina Rogozińska, Nadine Marlin, Louise Jackson, Girish Rayanagoudar, Anneloes E Ruifrok, Julie Dodds, Emma Molyneaux, Mireille Nm van Poppel, Lucilla Poston, Christina A Vinter, Fionnuala McAuliffe, Jodie M Dodd, Julie Owens, Ruben Barakat, Maria Perales, Jose G Cecatti, Fernanda Surita, SeonAe Yeo, Annick Bogaerts, Roland Devlieger, Helena Teede, Cheryce Harrison, Lene Haakstad, Garry X Shen, Alexis Shub, Nermeen El Beltagy, Narges Motahari, Janette Khoury, Serena Tonstad, Riitta Luoto, Tarja I Kinnunen, Kym Guelfi, Fabio Facchinetti, Elisabetta Petrella, Suzanne Phelan, Tânia T Scudeller, Kathrin Rauh, Hans Hauner, Kristina Renault, Christianne Jm de Groot, Linda R Sagedal, Ingvild Vistad, Signe Nilssen Stafne, Siv Mørkved, Kjell Å Salvesen, Dorte M Jensen, Márcia Vitolo, Arne Astrup, Nina Rw Geiker, Sally Kerry, Pelham Barton, Tracy Roberts, Richard D Riley, Arri Coomarasamy, Ben Willem Mol, Khalid S Khan, Shakila Thangaratinam
BACKGROUND: Diet- and physical activity-based interventions in pregnancy have the potential to alter maternal and child outcomes. OBJECTIVES: To assess whether or not the effects of diet and lifestyle interventions vary in subgroups of women, based on maternal body mass index (BMI), age, parity, Caucasian ethnicity and underlying medical condition(s), by undertaking an individual patient data (IPD) meta-analysis. We also evaluated the association of gestational weight gain (GWG) with adverse pregnancy outcomes and assessed the cost-effectiveness of the interventions...
August 2017: Health Technology Assessment: HTA
https://www.readbyqxmd.com/read/28795097/application-of-cu-mg-al-chitosan-o3-system-for-landfill-leachate-treatment-experimental-and-economic-evaluation-data
#13
Dariush Ranjbar Vakilabadi, Bahman Ramavandi, Amir Hessam Hassani, Ghasemali Omrani
Landfill leachate contains heavy organic pollutants, which pollute ground and surface waters. This dataset applied a newly-introduced catalyst, Cu/Mg/Al-chitosan, for a landfill leachate treatment during a catalytic oxidation. The data of chemical oxygen demand (COD) and colour removal from the leachate was reported as a function of reaction time (20-460 min). Economic evaluation data of the Cu/Mg/Al-chitosan-O3 system showed that the current cost of the system for treating each m(3) leachate is US$ 18 and for catalyst synthesis is US$ 54...
October 2017: Data in Brief
https://www.readbyqxmd.com/read/28794648/cost-analysis-of-adverse-events-associated-with-non-small-cell-lung-cancer-management-in-france
#14
Christos Chouaid, Delphine Loirat, Emilie Clay, Aurélie Millier, Chloé Godard, Amira Fannan, Laurie Lévy-Bachelot, Eric Angevin
BACKGROUND: Adverse events (AEs) related to medical treatments in non-small cell lung cancer (NSCLC) are frequent and need an appropriate costing in health economic models. Nevertheless, data on costs associated with AEs in NSCLC are scarce, particularly since the development of immunotherapy with specific immune-related AEs. OBJECTIVE: To estimate the costs of grades 3 and 4 AEs related to NSCLC treatments including immunotherapy in France. METHODS: Grades 3 and 4 AEs related to treatment and reported in at least 1% of patients in Phase III clinical trials for erlotinib, ramucirumab plus docetaxel, docetaxel, pemetrexed plus carboplatin plus bevacizumab, platinum-based chemotherapies, nivolumab and pembrolizumab were identified...
2017: ClinicoEconomics and Outcomes Research: CEOR
https://www.readbyqxmd.com/read/28776441/economic-evaluation-of-outpatient-parenteral-antimicrobial-therapy-a-systematic-review
#15
Eliane Molina Psaltikidis, Everton Nunes da Silva, Joaquim Murray Bustorff-Silva, Maria Luiza Moretti, Mariângela Ribeiro Resende
Outpatient parenteral antimicrobial therapy (OPAT) consists of providing antimicrobial therapy by parenteral infusion without hospitalization. A systematic review was performed to compare OPAT and hospitalization as health care modalities from an economic perspective. Areas covered: We identified 1455 articles using 13 electronic databases and manual searches. Two independent reviewers identified 35 studies conducted between 1978 and 2016. We observed high heterogeneity in the following: countries, infection site, OPAT strategies and outcomes analyzed...
August 4, 2017: Expert Review of Pharmacoeconomics & Outcomes Research
https://www.readbyqxmd.com/read/28776320/cost-effectiveness-of-support-for-people-starting-a-new-medication-for-a-long-term-condition-through-community-pharmacies-an-economic-evaluation-of-the-new-medicine-service-nms-compared-with-normal-practice
#16
Rachel A Elliott, Lukasz Tanajewski, Georgios Gkountouras, Anthony J Avery, Nick Barber, Rajnikant Mehta, Matthew J Boyd, Asam Latif, Antony Chuter, Justin Waring
BACKGROUND: The English community pharmacy New Medicine Service (NMS) significantly increases patient adherence to medicines, compared with normal practice. We examined the cost effectiveness of NMS compared with normal practice by combining adherence improvement and intervention costs with the effect of increased adherence on patient outcomes and healthcare costs. METHODS: We developed Markov models for diseases targeted by the NMS (hypertension, type 2 diabetes mellitus, chronic obstructive pulmonary disease, asthma and antiplatelet regimens) to assess the impact of patients' non-adherence...
August 3, 2017: PharmacoEconomics
https://www.readbyqxmd.com/read/28770641/evidence-on-the-cost-effectiveness-of-lifelong-antiretroviral-therapy-for-prevention-of-mother-to-child-transmission-of-hiv-implications-for-resource-limited-countries-in-sub-saharan-africa
#17
Peslie G Ngambi, Aubrey C Kalungia, Michael R Law, Francis Kalemeera, IIse Truter, Brian Godman, Derick Munkombwe
The 2016 World Health Organization (WHO) consolidated guideline recommends lifelong antiretroviral therapy (ART) for all HIV-infected pregnant and breastfeeding women for preventing mother-to-child HIV transmission (PMTCT). Ambiguity remains about the cost-effectiveness of this strategy in resource-limited developing countries. Areas Covered: We reviewed model-based studies on the cost-effectiveness of lifelong ART (formerly Option B+) relative to previous WHO guidelines for PMTCT. Our search using PubMed, Medline and Google Scholar for articles on Option B+ resulted in the final inclusion of seven studies published between 2012 and 2016...
August 3, 2017: Expert Review of Pharmacoeconomics & Outcomes Research
https://www.readbyqxmd.com/read/28770452/pertuzumab-for-the-neoadjuvant-treatment-of-early-stage-her2-positive-breast-cancer-an-evidence-review-group-perspective-of-a-nice-single-technology-appraisal
#18
REVIEW
Hazel Squires, Abdullah Pandor, Praveen Thokala, John W Stevens, Eva Kaltenthaler, Mark Clowes, Robert Coleman, Lynda Wyld
As part of its single technology appraisal process, the National Institute for Health and Care Excellence invited the manufacturer of pertuzumab (Perjeta(®); Roche Products Limited) to submit evidence of its clinical and cost- effectiveness for the neoadjuvant treatment of women with high-risk, early-stage, HER2-positive breast cancer when used in combination with trastuzumab and chemotherapy. High-risk women included those with locally advanced (including inflammatory) breast cancer and women with high-risk early-stage breast cancer (classified as T2/3 or N1)...
August 2, 2017: PharmacoEconomics
https://www.readbyqxmd.com/read/28770099/balance-right-in-multiple-sclerosis-brims-a-guided-self-management-programme-to-reduce-falls-and-improve-quality-of-life-balance-and-mobility-in-people-with-secondary-progressive-multiple-sclerosis-a-protocol-for-a-feasibility-randomised-controlled-trial
#19
H Gunn, J Andrade, L Paul, L Miller, S Creanor, C Green, J Marsden, P Ewings, M Berrow, J Vickery, A Barton, B Marshall, J Zajicek, J A Freeman
BACKGROUND: Impaired mobility is a cardinal feature of multiple sclerosis (MS) and is rated by people with MS as their highest priority. By the secondary progressive phase, balance, mobility and physical activity levels are significantly compromised; an estimated 70% of people with secondary progressive MS fall regularly. Our ongoing research has systematically developed 'Balance Right in MS' (BRiMS), an innovative, manualised 13-week guided self-management programme tailored to the needs of people with MS, designed to improve safe mobility and minimise falls...
2018: Pilot and Feasibility Studies
https://www.readbyqxmd.com/read/28764679/economic-evaluation-of-stepped-care-versus-usual-care-for-depression-and-anxiety-in-older-adults-with-vision-impairment-randomized-controlled-trial
#20
Hilde P A van der Aa, Ger H M B van Rens, Judith E Bosmans, Hannie C Comijs, Ruth M A van Nispen
BACKGROUND: A stepped-care program was found effective in preventing depressive and anxiety disorders in older adults with vision impairment. However, before a decision can be made about implementation, the cost-effectiveness of this program should be investigated. Therefore, we aimed to compare the cost-effectiveness of stepped-care versus usual care within low vision rehabilitation. METHODS: An economic evaluation from a societal perspective was performed alongside a multicenter randomized controlled trial...
August 1, 2017: BMC Psychiatry
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