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"Economic evaluation"

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https://www.readbyqxmd.com/read/28441507/new-metrics-for-economic-evaluation-in-the-presence-of-heterogeneity-focusing-on-evaluating-policy-alternatives-rather-than-treatment-alternatives
#1
David D Kim, Anirban Basu
BACKGROUND: Cost-effectiveness analysis (CEA) methods fail to acknowledge that where cost-effectiveness differs across subgroups, there may be differential adoption of technology. Also, current CEA methods are not amenable to incorporating the impact of policy alternatives that potentially influence the adoption behavior. Unless CEA methods are extended to allow for a comparison of policies rather than simply treatments, their usefulness to decision makers may be limited. METHODS: We conceptualize new metrics, which estimate the realized value of technology from policy alternatives, through introducing subgroup-specific adoption parameters into existing metrics, incremental cost-effectiveness ratios (ICERs) and Incremental Net Monetary Benefits (NMBs)...
April 1, 2017: Medical Decision Making: An International Journal of the Society for Medical Decision Making
https://www.readbyqxmd.com/read/28440898/comparing-induction-of-labour-with-oral-misoprostol-or-foley-catheter-at-term-cost-effectiveness-analysis-of-a-randomised-controlled-multi-centre-non-inferiority-trial
#2
Mieke L G Ten Eikelder, Gert-Jan van Baaren, Katrien Oude Rengerink, Marta Jozwiak, Jan Willem de Leeuw, Gunilla Kleiverda, Inge Evers, Karin de Boer, Josien Brons, Kitty W M Bloemenkamp, Ben W Mol
OBJECTIVE: To assess the costs of labour induction with oral misoprostol compared to Foley catheter. DESIGN: Economic evaluation alongside a randomised controlled trial. SETTING: Obstetric departments of six tertiary and 23 secondary care hospitals in the Netherlands. POPULATION: Women with a viable term singleton pregnancy in cephalic presentation, intact membranes, an unfavourable cervix (Bishop score <6) without a previous caesarean section, had been randomised for labour induction with oral misoprostol (n = 924) or Foley catheter (n = 921)...
April 25, 2017: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28436336/cardiovascular-screening-of-young-athletes-a-review-of-economic-evaluations
#3
Sophie Gerkens, Hans Van Brabandt, Anja Desomer, Christian Leonard, Mattias Neyt
OBJECTIVES: Some experts have promoted preparticipative cardiovascular screening programs for young athletes and have claimed that such programs were cost-effective without performing a critical analysis of studies supporting this statement. In this systematic review, a critical assessment of economic evaluations on these programs is performed to determine if they really provide value for money. METHODS: A systematic review of economic evaluations was performed on December 24, 2014...
April 24, 2017: International Journal of Technology Assessment in Health Care
https://www.readbyqxmd.com/read/28435820/costs-of-hospital-admission-on-primary-immunodeficiency-diseases
#4
Kheirollah Gholami, Elaheh Laali, Hassan Abolhassani, Alireza Ahmadvand, Niayesh Mohebbi, Mohammad Reza Javadi, Asghar Aghamohammadi, Nima Rezaei
BACKGROUND: Primary immunodeficiency diseases (PID) are heterogeneous group of inherited disorders mainly characterized by recurrent infections leading to several times hospital admissions. The economic impact of PID is a challenging issue; therefore, this study was designed to determine the medical costs of hospitalizations in this group of patients as an indicator of the direct cost of these diseases. METHODS: One hundred and ten children with PID hospitalized in the Children's Medical Center Hospital, Tehran, Iran were included in this study during Jan 2011 and Jan 2012...
March 2017: Iranian Journal of Public Health
https://www.readbyqxmd.com/read/28435128/randomized-trial-on-fast-track-care-in-colorectal-surgery-for-deep-infiltrating-endometriosis
#5
Marco Scioscia, Marcello Ceccaroni, Irene Gentile, Roberto Rossini, Roberto Clarizia, Davide Brunelli, Giacomo Ruffo
STUDY OBJECT: To study the application of a fast-track care protocol in colorectal surgery for deep infiltrating endometriosis. Bowel endometriosis is an infrequent but not rare condition that often needs intestinal surgery and imposes a high economic burden on society. DESIGN: Prospective randomized trial (Canadian Task Force I). SETTING: Tertiary referral center. PATIENTS: We randomly assigned 227 patients with preoperative evidence of bowel endometriosis to a fast-track (no preoperative bowel preparation, early restoration of diet, no postoperative antibiotics, and early post-operative mobilization) or conventional care for laparoscopic intestinal surgery...
April 18, 2017: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/28434392/does-the-eq-5d-capture-the-concerns-measured-by-the-palliative-care-outcome-scale-mapping-the-palliative-care-outcome-scale-onto-the-eq-5d-using-statistical-methods
#6
Mendwas D Dzingina, Paul McCrone, Irene J Higginson
BACKGROUND: The main measure to generate utility data for economic evaluations is the EQ-5D, but no study has tested whether or how to map from palliative care measures to the EQ-5D. AIMS: To assess the level of conceptual overlap between palliative outcomes and the EQ-5D, and the feasibility of mapping between them to obtain utilities for the Palliative care Outcome Scale. DESIGN: A cross-sectional secondary analysis of data from three studies...
April 1, 2017: Palliative Medicine
https://www.readbyqxmd.com/read/28432979/the-reality-of-economics-for-oncologists
#7
REVIEW
David Taylor
This article outlines the historical development of health economics and its present role in oncology related health technology assessments (HTAs). Despite concerns about the prices and immediate costs of new anticancer medicines for indications such as breast cancer overall spending on such treatments is affordable and offers long term value for money in countries such as the US, Canada and those of Western Europe. Oncologists wishing to protect the interests of current and future patients with both advanced and earlier stage cancers may be regarded as having a responsibility to understand the nature of health economic evaluations, and to be actively involved in decisions affecting access to current treatments and future levels of investment in incrementally improving therapies...
April 19, 2017: Breast: Official Journal of the European Society of Mastology
https://www.readbyqxmd.com/read/28432642/emerging-use-of-early-health-technology-assessment-in-medical-product-development-a-scoping-review-of-the-literature
#8
REVIEW
Maarten J IJzerman, Hendrik Koffijberg, Elisabeth Fenwick, Murray Krahn
Early health technology assessment is increasingly being used to support health economic evidence development during early stages of clinical research. Such early models can be used to inform research and development about the design and management of new medical technologies to mitigate the risks, perceived by industry and the public sector, associated with market access and reimbursement. Over the past 25 years it has been suggested that health economic evaluation in the early stages may benefit the development and diffusion of medical products...
April 21, 2017: PharmacoEconomics
https://www.readbyqxmd.com/read/28431515/the-effectiveness-of-creating-an-online-life-story-book-on-persons-with-early-dementia-and-their-informal-caregivers-a-protocol-of-a-randomized-controlled-trial
#9
Teuntje R Elfrink, Sytse U Zuidema, Miriam Kunz, Gerben J Westerhof
BACKGROUND: Dementia has a high burden for patients, informal caregivers and society. Given changes in care systems, more persons with dementia will live longer at home. However, living at home (with dementia) with a good quality of life is not easy to achieve. Dementia is often accompanied by neuropsychiatric symptoms like apathy, agitation, depression, and anxiety, which have a negative impact on quality of life. Whereas cognitive deterioration can hardly be influenced, it is possible to reduce neuropsychiatric symptoms...
April 21, 2017: BMC Geriatrics
https://www.readbyqxmd.com/read/28428734/defining-a-staged-based-process-for-economic-and-financial-evaluations-of-mhealth-programs
#10
Amnesty E LeFevre, Samuel D Shillcutt, Sean Broomhead, Alain B Labrique, Tom Jones
Mobile and wireless technology for health (mHealth) has the potential to improve health outcomes by addressing critical health systems constraints that impede coverage, utilization, and effectiveness of health services. To date, few mHealth programs have been implemented at scale and there remains a paucity of evidence on their effectiveness and value for money. This paper aims to improve understanding among mHealth program managers and key stakeholders of how to select methods for economic evaluation (comparative analysis for determining value for money) and financial evaluation (determination of the cost of implementing an intervention, estimation of costs for sustaining or expanding an intervention, and assessment of its affordability)...
2017: Cost Effectiveness and Resource Allocation: C/E
https://www.readbyqxmd.com/read/28428184/clinical-and-cost-effectiveness-safety-and-acceptability-of-community-intravenous-antibiotic-service-models-civas-systematic-review
#11
E D Mitchell, C Czoski Murray, D Meads, J Minton, J Wright, M Twiddy
OBJECTIVE: Evaluate evidence of the efficacy, safety, acceptability and cost-effectiveness of outpatient parenteral antimicrobial therapy (OPAT) models. DESIGN: A systematic review. DATA SOURCES: MEDLINE, EMBASE, CINAHL, Cochrane Library, National Health Service (NHS) Economic Evaluation Database (EED), Research Papers in Economics (RePEc), Tufts Cost-Effectiveness Analysis (CEA) Registry, Health Business Elite, Health Information Management Consortium (HMIC), Web of Science Proceedings, International Pharmaceutical Abstracts, British Society for Antimicrobial Chemotherapy website...
April 20, 2017: BMJ Open
https://www.readbyqxmd.com/read/28427846/vaccines-are-different-a-systematic-review-of-budget-impact-analyses-of-vaccines
#12
REVIEW
Priscilla Magalhaes Loze, Luciana Bertholim Nasciben, Ana Marli Christovam Sartori, Alexander Itria, Hillegonda Maria Dutilh Novaes, Patrícia Coelho de Soárez
INTRODUCTION: Several countries require manufacturers to present a budget impact analysis (BIA), together with a cost-effectiveness analysis, to support national funding requests. However, guidelines for conducting BIA of vaccines are scarce. OBJECTIVES: To analyze the methodological approaches used in published budget impact analysis (BIA) of vaccines, discussing specific methodological issues related to vaccines. MATERIAL AND METHODS: This systematic review of the literature on BIA of vaccines was carried out in accordance with the Centre for Reviews and Dissemination - CRD guidelines...
April 17, 2017: Vaccine
https://www.readbyqxmd.com/read/28426345/economic-evaluation-of-ezetimibe-treatment-in-combination-with-statin-therapy-in-the-united-states
#13
Glenn M Davies, Ami Vyas, Carl A Baxter
AIMS: This study assessed the cost-effectiveness of ezetimibe with statin therapy versus statin monotherapy from a United States (US) payer perspective, assuming the impending patent expiration of ezetimibe. METHODS: A Markov-like economic model consisting of 28 distinct health states was used. Model population data were obtained from US linked claims and electronic medical records, with inclusion criteria based on diagnostic guidelines. Inputs came from recent clinical trials, meta-analyses, and cost-effectiveness analyses...
April 20, 2017: Journal of Medical Economics
https://www.readbyqxmd.com/read/28420539/hta-and-decision-making-processes-in-central-eastern-and-south-eastern-europe-results-from-a-survey
#14
Leticia García-Mochón, Jaime Espín Balbino, Antonio Olry de Labry Lima, Araceli Caro Martinez, Eva Martin Ruiz, Román Pérez Velasco
OBJECTIVE: To gain knowledge and insights on health technology assessment (HTA) and decision-making processes in Central, Eastern and South Eastern Europe (CESEE) countries. METHODS: A cross-sectional study was performed. Based on the literature, a questionnaire was developed in a multi-stage process. The questionnaire was arranged according to 5 broad domains: (i) introduction/country settings; (ii) use of HTA in the country; (iii) decision-making process; (iv) implementation of decisions; and (v) HTA and decision-making: future challenges...
March 31, 2017: Health Policy
https://www.readbyqxmd.com/read/28418761/economic-evaluation-of-a-hospital-based-palliative-care-program
#15
Sarina R Isenberg, Chunhua Lu, John McQuade, Rab Razzak, Brian W Weir, Natasha Gill, Thomas J Smith, David R Holtgrave
PURPOSE: Establish costs of an inpatient palliative care unit (PCU) and conduct a threshold analysis to estimate the maximum possible costs for the PCU to be considered cost effective. METHODS: We used a hospital perspective to determine costs on the basis of claims from administrative data from Johns Hopkins PCU between March 2013 and March 2014. Using existing literature, we estimated the number of quality-adjusted life years (QALYs) that the PCU could generate...
April 18, 2017: Journal of Oncology Practice
https://www.readbyqxmd.com/read/28414567/disease-burden-of-community-acquired-pneumonia-among-children-under-5%C3%A2-y-old-in-china-a-population-based-survey
#16
Yan Li, Zhijie An, Dapeng Yin, Yanmin Liu, Zhuoying Huang, Yujie Ma, Hui Li, Qi Li, Huaqing Wang
BACKGROUND: To obtain the baseline data on the incidence and cost of community acquired pneumonia among under-5 children for future studies, and provide evidence for shaping China's strategies regarding pneumococcal conjugate vaccine (PCV). METHODS: Three townships from Heilongjiang, Hebei and Gansu Province and one community in Shanghai were selected as study areas. A questionnaire survey was conducted to collect data on incidence and cost of pneumonia among children under 5 y old in 2012...
April 17, 2017: Human Vaccines & Immunotherapeutics
https://www.readbyqxmd.com/read/28410960/a-randomized-controlled-trial-of-a-citywide-emergency-department-care-coordination-program-to-reduce-prescription-opioid-related-visits-an-economic-evaluation
#17
Sean M Murphy, Donelle Howell, Sterling McPherson, Rebecca Grohs, John Roll, Darin Neven
BACKGROUND: Care provided in the emergency department (ED) can cost up to five times as much as care received for comparable diagnoses in alternative settings. Small groups of patients, many of whom suffer from an opioid use disorder, often account for a large proportion of total ED visits. We recently conducted, and demonstrated the effectiveness of, the first randomized controlled trial of a citywide ED care-coordination program intending to reduce prescription-opioid-related ED visits...
April 12, 2017: Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28410779/quantifying-health-utilities-in-patients-undergoing-stereotactic-body-radiation-treatment-for-liver-metastases-for-use-in-future-economic-evaluations
#18
B Warren, P Munoz-Schuffenegger, K K W Chan, W Chu, J Helou, D Erler, H Chung
AIM: Stereotactic body radiation therapy (SBRT) is increasingly used as an option for those with liver metastases. In order to facilitate future economic impact of health technologies, health utility scores may be used. The EuroQOL-5D-3L (EQ-5D) preference-based healthy utility instrument was used to evaluate the impact of treatment with SBRT on health utility scores. MATERIALS AND METHODS: Between August 2013 and October 2014, 31 patients treated with 3-5 fractions of SBRT for liver metastases were enrolled in this study...
April 12, 2017: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/28410761/impact-of-surgical-site-infection-on-healthcare-costs-and-patient-outcomes-a-systematic-review-in-six-european-countries
#19
REVIEW
J M Badia, A L Casey, N Petrosillo, P M Hudson, S A Mitchell, C Crosby
BACKGROUND: Surgical site infections (SSIs) are associated with increased morbidity and mortality. Furthermore, SSIs constitute a financial burden and negatively impact on patient quality of life (QoL). AIM: To assess, and evaluate the evidence for, the cost and health-related QoL (HRQoL) burden of SSIs across various surgical specialties in six European countries. METHODS: Electronic databases and conference proceedings were systematically searched to identify studies reporting the cost and HRQoL burden of SSIs...
March 8, 2017: Journal of Hospital Infection
https://www.readbyqxmd.com/read/28410588/evidence-synthesis-to-inform-model-based-cost-effectiveness-evaluations-of-diagnostic-tests-a-methodological-review-of-health-technology-assessments
#20
Bethany Shinkins, Yaling Yang, Lucy Abel, Thomas R Fanshawe
BACKGROUND: Evaluations of diagnostic tests are challenging because of the indirect nature of their impact on patient outcomes. Model-based health economic evaluations of tests allow different types of evidence from various sources to be incorporated and enable cost-effectiveness estimates to be made beyond the duration of available study data. To parameterize a health-economic model fully, all the ways a test impacts on patient health must be quantified, including but not limited to diagnostic test accuracy...
April 14, 2017: BMC Medical Research Methodology
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