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https://www.readbyqxmd.com/read/29650060/gastrostomy-versus-nasogastric-tube-feeding-for-chemoradiation-patients-with-head-and-neck-cancer-the-tube-pilot-rct
#1
Vinidh Paleri, Joanne Patterson, Nikki Rousseau, Eoin Moloney, Dawn Craig, Dimitrios Tzelis, Nina Wilkinson, Jeremy Franks, Ann Marie Hynes, Ben Heaven, David Hamilton, Teresa Guerrero-Urbano, Rachael Donnelly, Stewart Barclay, Tim Rapley, Deborah Stocken
BACKGROUND: Approximately 9000 new cases of head and neck squamous cell cancers (HNSCCs) are treated by the NHS each year. Chemoradiation therapy (CRT) is a commonly used treatment for advanced HNSCC. Approximately 90% of patients undergoing CRT require nutritional support via gastrostomy or nasogastric tube feeding. Long-term dysphagia following CRT is a primary concern for patients. The effect of enteral feeding routes on swallowing function is not well understood, and the two feeding methods have, to date (at the time of writing), not been compared...
April 2018: Health Technology Assessment: HTA
https://www.readbyqxmd.com/read/29649837/-cost-effectiveness-and-cost-utility-analyses-of-antireflux-medicine
#2
Ines Gockel, Undine Gabriele Lange, Olaf Schürmann, Boris Jansen-Winkeln, Rainer Sibbel, Orestis Lyros, Nikolaus von Dercks
INTRODUCTION: Laparoscopic antireflux surgery and medical therapy with proton pump inhibitors are gold standards of gastroesophageal reflux treatment. On account of limited resources and increasing healthcare needs and costs, in this analysis, not only optimal medical results, but also superiority in health economics of these 2 methods are evaluated. METHODS: We performed an electronic literature survey in MEDLINE, PubMed, Cochrane Library, ISRCTN (International Standard Randomization Controlled Trial Number) as well as in the NHS Economic Evaluation Database, including studies published until 1/2017...
April 12, 2018: Das Gesundheitswesen
https://www.readbyqxmd.com/read/29643263/health-state-utilities-for-patient-s-current-health-from-bipolar-type-i-disorder
#3
Masoumeh Banihashemian, Arash Rashidian, Faeze Gholamian, Mahboubeh Parsaeian, Najmeh Moradi, Homayoun Amini
BACKGROUND: Bipolar Type I Disorder (BID) is a disabling mental disorder among young adults that places enormous psychological, social, and economic burdens on patients, their families, and health care systems and decreases quality of life (QOL). Few studies have investigated the quality-adjusted life-years (QALY), health state preferences, and utilities in patients with BID. AIM OF STUDY: The aim of this study was to elicit health state utilities for current health among a sample of individuals with BID irrespective of their clinical conditions at the time of evaluation...
March 1, 2018: Journal of Mental Health Policy and Economics
https://www.readbyqxmd.com/read/29626629/the-burden-of-allergic-rhinitis-and-allergic-rhinoconjunctivitis-on-adolescents-a-literature-review
#4
REVIEW
Michael S Blaiss, Eva Hammerby, Susan Robinson, Tessa Kennedy-Martin, Sarah Buchs
OBJECTIVE: To evaluate the literature regarding the burden of allergic rhinitis (AR) and allergic rhinoconjunctivitis (ARC) in adolescents (10-19 years). DATA SOURCES: Searches were performed in MEDLINE, Embase, Health Technology Assessment Database, and National Health Service Economic Evaluation Database for studies evaluating concepts of symptoms, quality of life (QOL), daily activities, sleep, examination performance, school absenteeism and presenteeism, and treatment burden in adolescents with AR or ARC...
April 4, 2018: Annals of Allergy, Asthma & Immunology
https://www.readbyqxmd.com/read/29626176/preventive-antibiotics-in-stroke-study-pass-a-cost-effectiveness-study
#5
Willeke F Westendorp, Elles Zock, Jan-Dirk Vermeij, Henk Kerkhoff, Paul J Nederkoorn, Marcel G W Dijkgraaf, Diederik van de Beek
OBJECTIVE: To evaluate the cost-effectiveness of preventive ceftriaxone vs standard stroke unit care without preventive antimicrobial therapy in acute stroke patients. METHODS: In this multicenter, randomized, open-label trial with masked endpoint assessment, 2,550 patients with acute stroke were included between 2010 and 2014. Economic evaluation was performed from a societal perspective with a time horizon of 3 months. Volumes and costs of direct, indirect, medical, and nonmedical care were assessed...
April 6, 2018: Neurology
https://www.readbyqxmd.com/read/29625764/systematic-review-of-cost-effectiveness-studies-of-human-papillomavirus-hpv-vaccination-9-valent-vaccine-gender-neutral-and-multiple-age-cohort-vaccination
#6
REVIEW
Siok Shen Ng, Raymond Hutubessy, Nathorn Chaiyakunapruk
BACKGROUND: The success of human papillomavirus (HPV) national immunization program depends on effective strategies in optimizing the uptake of HPV vaccine. Given the increasing number of economic evaluations, this review was conducted to update the economic evidence on HPV vaccination, by focusing on: (i) 9-valent vaccine compared to bi- or quadrivalent vaccine; (ii) gender-neutral vaccination compared to female only vaccination; and (iii) multiple age cohort immunization compared to single age cohort immunization...
April 3, 2018: Vaccine
https://www.readbyqxmd.com/read/29625534/burden-of-illness-of-chemotherapy-in-castration-resistant-prostate-cancer-patients-in-japan-a-retrospective-database-analysis
#7
Joerg Mahlich, Akiko Tsubota, Keiichiro Imanaka, Kentaro Enjo
OBJECTIVE: The objective was to assess the burden of chemotherapy for castration resistant prostate cancer (CRPC) in Japan. METHODS: Utilizing a large administrative hospital data base we compared a set of outcome measures twelve months before and after initiation of chemotherapy, namely total medical costs, number of outpatient visits, number of hospital admissions, and number of days spent in hospital. RESULTS: A total of 598 CRPC patients were identified in the database...
April 6, 2018: Current Medical Research and Opinion
https://www.readbyqxmd.com/read/29623676/cost-effectiveness-of-the-breconda-decision-aid-for-women-with-breast-cancer-results-from-a-randomized-controlled-trial
#8
Bonny Parkinson, Kerry A Sherman, Paul Brown, Laura-Kate E Shaw, John Boyages, Linda D Cameron, Elisabeth Elder, Thomas Lam
OBJECTIVE: To report on the cost-effectiveness of BRECONDA (Breast RECONstruction Decision Aid), a web-based decision aid to facilitate decisions regarding breast reconstruction surgery, with usual care for women with breast cancer. METHODS: The economic evaluation was conducted alongside a randomized controlled trial. Women diagnosed with breast cancer or ductal carcinoma in situ and eligible for breast reconstruction following mastectomy were randomized to access BRECONDA for 6 months + usual care (n = 106) or usual care (n = 116) and were assessed at baseline preintervention, and then 1-month and 6-months post-randomization...
April 5, 2018: Psycho-oncology
https://www.readbyqxmd.com/read/29623634/a-review-of-clinical-and-economic-evaluations-applied-to-psychotropic-therapies-used-in-the-treatment-of-schizophrenia-in-argentina
#9
REVIEW
Gisela Paula González, Nebel Silvana Moscoso, Fernando Pablo Lago
Schizophrenia is considered a serious mental disorder that affects over 21 million people worldwide, and is associated with disability that frequently affects the patient's educational and working performance. In Argentina, two of the most widely used antipsychotics in the treatment of this disorder are haloperidol and risperidone. Both are provided free to patients without health coverage in public healthcare facilities. In this paper we seek to review the clinical and economic benefits of prescribing psychotropic therapies based on haloperidol (a first-generation antipsychotic that is part of the butyrophenone group of drugs) versus risperidone [an atypical or second-generation antipsychotic (neuroleptic) drug] in adult patients who have been diagnosed with schizophrenia...
October 23, 2017: PharmacoEconomics Open
https://www.readbyqxmd.com/read/29623627/cost-effectiveness-of-stapled-haemorrhoidopexy-and-traditional-excisional-surgery-for-the-treatment-of-haemorrhoidal-disease
#10
Mary M Kilonzo, Steven R Brown, Hanne Bruhn, Jonathan A Cook, Jemma Hudson, John Norrie, Angus J M Watson, Jessica Wood
OBJECTIVE: Our objective was to compare the cost effectiveness of stapled haemorrhoidopexy (SH) and traditional haemorrhoidectomy (TH) in the treatment of grade II-IV haemorrhoidal disease from the perspective of the UK national health service. METHODS: An economic evaluation was conducted alongside an open, two-arm, parallel-group, pragmatic, multicentre, randomised controlled trial conducted in several hospitals in the UK. Patients were randomised into either SH or TH surgery between January 2011 and August 2014 and were followed up for 24 months...
August 25, 2017: PharmacoEconomics Open
https://www.readbyqxmd.com/read/29623624/the-economic-burden-of-small-cell-lung-cancer-a-systematic-review-of-the-literature
#11
REVIEW
Ashley Enstone, Maire Greaney, Manca Povsic, Robin Wyn, John R Penrod, Yong Yuan
BACKGROUND: Small cell lung cancer (SCLC), the most aggressive form of lung carcinoma, represents approximately 15% of all lung cancers; however, the economic and healthcare burden of SCLC is not well-defined. OBJECTIVE: The aim of this study was to explore the impact of SCLC on healthcare costs through a systematic literature review (SLR). METHODS: Using the OVID search engine, the SLR was conducted in PubMed, MEDLINE In-Process, EMBASE, EconLIT and the National Health Service Economic Evaluation Database (NHS EED)...
August 18, 2017: PharmacoEconomics Open
https://www.readbyqxmd.com/read/29623620/economic-evaluation-of-midazolam-droperidol-combination-versus-droperidol-or-olanzapine-for-the-management-of-acute-agitation-in-the-emergency-department-a-within-trial-analysis
#12
Celene Y L Yap, Ya-Seng Arthur Hsueh, Jonathan C Knott, David McD Taylor, Esther W Chan, David C M Kong
BACKGROUND: The combination of midazolam and droperidol has proven superior to droperidol or olanzapine monotherapy in the management of acute agitation in emergency departments (EDs). OBJECTIVE: This is the first economic analysis to evaluate the cost-benefit and cost effectiveness of the midazolam-droperidol combination compared with droperidol or olanzapine for the management of acute agitation in EDs. METHODS: This analysis used data derived from a randomised, controlled, double-blind clinical trial conducted in two metropolitan Australian EDs between October 2014 and August 2015...
July 24, 2017: PharmacoEconomics Open
https://www.readbyqxmd.com/read/29623616/does-methodological-guidance-produce-consistency-a-review-of-methodological-consistency-in-breast-cancer-utility-value-measurement-in-nice-single-technology-appraisals
#13
REVIEW
Micah Rose, Stephen Rice, Dawn Craig
Since 2004, National Institute for Health and Care Excellence (NICE) methodological guidance for technology appraisals has emphasised a strong preference for using the validated EuroQol 5-Dimensions (EQ-5D) quality-of-life instrument, measuring patient health status from patients or carers, and using the general public's preference-based valuation of different health states when assessing health benefits in economic evaluations. The aim of this study was to review all NICE single technology appraisals (STAs) for breast cancer treatments to explore consistency in the use of utility scores in light of NICE methodological guidance...
July 5, 2017: PharmacoEconomics Open
https://www.readbyqxmd.com/read/29618414/systematic-review-of-economic-evaluations-of-the-23-valent-pneumococcal-polysaccharide-vaccine-ppv23-in-individuals-60-years-of-age-or-older
#14
REVIEW
Alvaro Mitsunori Nishikawa, Ana Marli Christovam Sartori, Giulia Marcelino Mainardi, Angela Carvalho Freitas, Alexander Itria, Hillegonda Maria Dutilh Novaes, Patrícia Coelho de Soárez
OBJECTIVES: To systematically review the economic evaluations of 23-valent pneumococcal polysaccharide vaccine (PPV23) in adults aged ≥60 years to inform the development of local studies through the discussion of parameters and assumptions that influence the results of the analyses. METHODS: We searched the MEDLINE, Excerpta Medica, Cochrane Library, Latin-American and Caribbean Health Sciences Literature (LILACS), Brazilian Regional Library of Medicine, National Health Service Economic Evaluation, and Centre for Reviews and Dissemination-as well as the Scopus citation index and the Web of Science for full economic evaluations of PPV23 published up to March 2016...
April 2, 2018: Vaccine
https://www.readbyqxmd.com/read/29616674/costs-and-effectiveness-of-influenza-vaccination-a-systematic-review
#15
Lucia Sara D'Angiolella, Alessandra Lafranconi, Paolo Angelo Cortesi, Silvia Rota, Giancarlo Cesana, Lorenzo Giovanni Mantovani
BACKGROUND: Seasonal influenza can cause a significant public health burden. Vaccination is proposed as the most effective measure to prevent influenza and related undesired outcomes. OBJECTIVE: To estimate the efficiency of influenza vaccination. METHODS: A literature review of economic evaluations of influenza vaccinations, published over the last 5 years, was performed using MEDLINE (through PubMed), Web of Science and Scopus. RESULTS: 935 papers were identified and 30 were selected, including studies performed in different population subgroups: general population, children, adults, elderly, pregnant women and high risk patients...
January 2018: Annali Dell'Istituto Superiore di Sanità
https://www.readbyqxmd.com/read/29616427/people-in-states-worse-than-dead-according-to-the-eq-5d-uk-value-set-would-they-rather-be-dead
#16
Lars Bernfort, Björn Gerdle, Magnus Husberg, Lars-Åke Levin
PURPOSE: Quality-adjusted life years (QALYs) measure health by combining length and quality of life. QALYs constitute the effect side of incremental cost-effectiveness ratios, describing the results of health economic evaluations. The objectives of this study were to (1) investigate the prevalence of states worse than dead (SWD) when using the EuroQol-5D UK value set, and (2) to study to what extent SWDs are reasonable with a starting point in experience-based valuations of health states...
April 3, 2018: Quality of Life Research
https://www.readbyqxmd.com/read/29615442/cost-effectiveness-of-interventions-to-control-cardiovascular-diseases-and-diabetes-mellitus-in-south-asia-a-systematic-review
#17
Kavita Singh, Ambalam M Chandrasekaran, Soumyadeep Bhaumik, Kaushik Chattopadhyay, Anuji Upekshika Gamage, Padmal De Silva, Ambuj Roy, Dorairaj Prabhakaran, Nikhil Tandon
OBJECTIVES: More than 80% of cardiovascular diseases (CVD) and diabetes mellitus (DM) burden now lies in low and middle-income countries. Hence, there is an urgent need to identify and implement the most cost-effective interventions, particularly in the resource-constraint South Asian settings. Thus, we aimed to systematically review the cost-effectiveness of individual-level, group-level and population-level interventions to control CVD and DM in South Asia. METHODS: We searched 14 electronic databases up to August 2016...
April 3, 2018: BMJ Open
https://www.readbyqxmd.com/read/29611869/contracting-out-to-improve-the-use-of-clinical-health-services-and-health-outcomes-in-low-and-middle-income-countries
#18
REVIEW
Willem A Odendaal, Kim Ward, Jesse Uneke, Henry Uro-Chukwu, Dereck Chitama, Yusentha Balakrishna, Tamara Kredo
BACKGROUND: Contracting out of governmental health services is a financing strategy that governs the way in which public sector funds are used to have services delivered by non-governmental health service providers (NGPs). It represents a contract between the government and an NGP, detailing the mechanisms and conditions by which the latter should provide health care on behalf of the government. Contracting out is intended to improve the delivery and use of healthcare services. This Review updates a Cochrane Review first published in 2009...
April 3, 2018: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29611148/what-is-the-current-evidence-of-the-impact-on-quality-of-life-whilst-waiting-for-management-treatment-of-orthopaedic-musculoskeletal-complaints-a-systematic-scoping-review
#19
Joanne Morris, Asterie Twizeyemariya, Karen Grimmer
PURPOSE: To describe quality of life (QoL) outcome measures that are reported in the literature in patients waiting for outpatient orthopaedic/musculoskeletal specialist care and how waiting impacts on QoL in these terms. METHODS: A subset of studies reporting on QoL outcome measures were extracted from literature identified in a recent scoping search of Medline, Embase, Pubmed, NHS Economic Evaluation Database (Prospero registration CRD42016047332). The systematic scoping search examined impacts on patients waiting for orthopaedic specialist care...
April 2, 2018: Quality of Life Research
https://www.readbyqxmd.com/read/29611047/economic-studies-on-non-communicable-diseases-and-injuries-in-india-a-systematic-review
#20
REVIEW
Indrani Gupta, Arjun Roy
BACKGROUND: The burden from non-communicable diseases and injuries (NCDI) in India is increasing rapidly. With low public sector investment in the health sector generally, and a high financial burden on households for treatment, it is important that economic evidence is used to set priorities in the context of NCDI. OBJECTIVE: Our objective was to understand the extent to which economic analysis has been used in India to (1) analyze the impact of NCDI and (2) evaluate prevention and treatment interventions...
April 2, 2018: Applied Health Economics and Health Policy
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