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"Economic evaluation"

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https://www.readbyqxmd.com/read/28545094/economic-evaluation-of-policy-options-for-dialysis-in-end-stage-renal-disease-patients-under-the-universal-health-coverage-in-indonesia
#1
Afiatin, Levina Chandra Khoe, Erna Kristin, Lusiana Siti Masytoh, Eva Herlinawaty, Pitsaphun Werayingyong, Mardiati Nadjib, Sudigdo Sastroasmoro, Yot Teerawattananon
OBJECTIVES: This study aims to assess the value for money and budget impact of offering hemodialysis (HD) as a first-line treatment, or the HD-first policy, and the peritoneal dialysis (PD) first policy compared to a supportive care option in patients with end-stage renal disease (ESRD) in Indonesia. METHODS: A Markov model-based economic evaluation was performed using local and international data to quantify the potential costs and health-related outcomes in terms of life years (LYs) and quality-adjusted life years (QALYs)...
2017: PloS One
https://www.readbyqxmd.com/read/28538691/the-potential-cost-effectiveness-of-pre-exposure-prophylaxis-combined-with-hiv-vaccines-in-the-united-states
#2
Blythe J S Adamson, Josh J Carlson, James G Kublin, Louis P Garrison
This economic evaluation aims to support policy-making on the combined use of pre-exposure prophylaxis (PrEP) with HIV vaccines in development by evaluating the potential cost-effectiveness of implementation that would support the design of clinical trials for the assessment of combined product safety and efficacy. The target study population is a cohort of men who have sex with men (MSM) in the United States. Policy strategies considered include standard HIV prevention, daily oral PrEP, HIV vaccine, and their combination...
May 24, 2017: Vaccines
https://www.readbyqxmd.com/read/28535969/economic-evaluation-of-infection-control-activities
#3
Takayuki Seko, Tomoya Tachi, Naoki Kawashima, Teruo Maeda, Minako Yasuda, Yoshihiro Noguchi, Hitomi Teramachi
BACKGROUND: Healthcare-associated infections by drug-resistant bacteria affect a patient's prognosis. Infection control activities at medical institutions in Japan are increasingly focused on the threat from these bacteria. AIM: Infection control activities incur various costs. The aim of this study was to undertake a full cost analysis that included the costs of consumables and labour required for infection control activities. METHODS: We surveyed the cost of infection control activities undertaken by the infection control team (ICT) at Nishimino Kosei Hospital in Japan, from January 2013 to December 2015...
May 20, 2017: Journal of Hospital Infection
https://www.readbyqxmd.com/read/28535440/management-of-ventilator-associated-pneumonia-with-a-new-antibiotic-adjuvant-entity-ceftriaxone-sulbactam-disodium-edetate-a-novel-approach-to-spare-carbapenems
#4
Prachee Sathe, Sagar Maddani, Shilpa Kulkarni, Nita Munshi
BACKGROUND: Ventilator associated pneumonia (VAP) is one of the most serious nosocomial infections in Intensive Care Unit (ICU). The aim of this study was to evaluate a new approach to spare the carbapenems for the management of patients diagnosed with VAP due to Acinetobacter baumannii (A. baumannii). METHOD: This retrospective study was conducted on VAP patients presenting for treatment at tertiary care centre between May 2014 and March 2016. The case sheets of patients who have been treated for VAP with meropenem, antibiotic adjuvant entity (AAE) and colistin were analysed...
May 15, 2017: Journal of Critical Care
https://www.readbyqxmd.com/read/28534268/impact-of-thyme-powder-thymus-vulgaris-l-supplementation-on-gene-expression-profiles-of-cytokines-and-economic-efficiency-of-broiler-diets
#5
Fardos A M Hassan, Ashraf Awad
This study was conducted in an attempt to evaluate the impact of thyme powder supplementation on broiler diets with respect to cytokine and mucin2 gene expressions. It was also our aim to evaluate the growth performance, blood biochemical and hematological profiles, and economic efficiency of the diet. A total of 120 1-day old chicks (Cobb 500) were divided into four groups on the basis of the diet. One group received a basal diet (control) while the others received a basal diet supplemented with 2, 5, or 8 g/kg of thyme powder...
May 23, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28531205/cost-analysis-of-human-papillomavirus-related-cervical-diseases-and-genital-warts-in-swaziland
#6
Themba G Ginindza, Benn Sartorius, Xolisile Dlamini, Ellinor Östensson
BACKGROUND: Human papillomavirus (HPV) has proven to be the cause of several severe clinical conditions on the cervix, vulva, vagina, anus, oropharynx and penis. Several studies have assessed the costs of cervical lesions, cervical cancer (CC), and genital warts. However, few have been done in Africa and none in Swaziland. Cost analysis is critical in providing useful information for economic evaluations to guide policymakers concerned with the allocation of resources in order to reduce the disease burden...
2017: PloS One
https://www.readbyqxmd.com/read/28528578/a-cluster-randomized-trial-to-reduce-caesarean-delivery-rates-in-quebec-cost-effectiveness-analysis
#7
Mira Johri, Edmond S W Ng, Clara Bermudez-Tamayo, Jeffrey S Hoch, Thierry Ducruet, Nils Chaillet
BACKGROUND: Widespread increases in caesarean section (CS) rates have sparked concerns about risks to mothers and infants and rising healthcare costs. A multicentre, two-arm, cluster-randomized trial in Quebec, Canada assessed whether an audit and feedback intervention targeting health professionals would reduce CS rates for pregnant women compared to usual care, and concluded that it reduced CS rates without adverse effects on maternal or neonatal health. The effect was statistically significant but clinically small...
May 22, 2017: BMC Medicine
https://www.readbyqxmd.com/read/28528557/-naming-and-framing-the-impact-of-labeling-on-health-state-values-for-multiple-sclerosis
#8
Colin Green, Elizabeth Goodwin, Annie Hawton
INTRODUCTION: Health state valuation is a key input in many economic evaluations that inform resource allocation across competing healthcare interventions. Empirical evidence has shown that, in preference elicitation surveys, respondents may value a health state differently if they are aware of the condition causing it ('labeling effects'). This study investigates the impact of including a multiple sclerosis (MS) label for valuation of MS health states. METHODS: Health state values for MS were elicited using two internet-based surveys in representative samples of the UK population ( n = 1702; n = 1788)...
May 1, 2017: Medical Decision Making: An International Journal of the Society for Medical Decision Making
https://www.readbyqxmd.com/read/28525725/a-comparison-of-the-validity-and-responsiveness-of-the-eq-5d-5l-and-sf-6d-for-measuring-health-spillovers-a-study-of-the-family-impact-of-meningitis
#9
Arjun Bhadhuri, Sue Jowett, Kate Jolly, Hareth Al-Janabi
BACKGROUND: The "health spillover" of patient illness on family members is important to capture in economic evaluation. This study compares the construct validity and responsiveness of 2 widely used health-related quality-of-life instruments, the EQ-5D-5L and SF-6D, in capturing health spillover effects for family members with and without an informal care role (carers and noncarers). METHODS: Construct validity and responsiveness were assessed using data from a 2012 UK survey of the family impact of meningitis-related sequelae...
May 1, 2017: Medical Decision Making: An International Journal of the Society for Medical Decision Making
https://www.readbyqxmd.com/read/28521614/overcoming-platinum-resistance-in-ovarian-cancer-treatment-from-clinical-practice-to-emerging-chemical-therapies
#10
Federica Tomao, Claudia Marchetti, Alessia Romito, Anna Di Pinto, Violante Di Donato, Innocenza Palaia, Marco Monti, Ludovico Muzii, Pierluigi Benedetti Panici
The objective of this review is to summarize results from clinical trials that tested cytotoxic drugs and target strategies for the treatment of platinum resistant (PR) recurrent ovarian cancer (ROC) with particular attention to Phase III and ongoing trials. Areas covered: Since platinum free interval (PFI) represents the most important predictive factor for response to platinum re-treatment in ROC, non-platinum regimens are conventionally considered the most appropriate approaches. Impressive progress has been made in recent decades, resulting in the identification of most effective cytotoxic agents and in the development of new target strategies...
May 18, 2017: Expert Opinion on Pharmacotherapy
https://www.readbyqxmd.com/read/28521377/-checklist-for-the-development-and-assessment-of-cost-of-illness-studies
#11
Dirk Müller, Stephanie Stock, Charalabos-Markos Dintsios, Nadja Chernyak, Andreas Gerber-Grote, Tristan Daniel Gloede, Benita Hermann, Eduard Huppertz, Fabian Jülich, Sarah Mostardt, Juliane Köberlein-Neu, Anne Prenzler, Hans-Joachim Salize, Sara Santos, Benjamin Scheckel, Astrid Seidl, Katharina Wahlers, Andrea Icks
Background Cost-of-illness (CoI) studies are important instruments for estimating the socioeconomic burden of specified diseases. CoI studies provide important information about the cost structure of a disease, the resulting research need, approaches to improve aspects of care and, monetary consequences from different perspectives. This information can be useful for healthcare research and health policy. Due to heterogeneity of available Cost-of-Illness studies, the working group 'Health Economics' of the German Network for Healthcare Research (DNVF) in accordance with the German Society for Health Economics (DGGÖ) developed an instrument for the planning, conduct and assessment of CoI studies...
May 18, 2017: Das Gesundheitswesen
https://www.readbyqxmd.com/read/28520447/-controversies-around-qalys
#12
Vladimír Rogalewicz, Miroslav Barták
The paper summarizes the criticisms of the QALY concept utilization in health-economic evaluations that has been growing stronger in the last years. Despite of its limitations, the QALY concept has been routinely used in many countries incl. the Czech Republic. However, some states disapproved QALYs as an optimizing criterion at the level of their political decisions. The critical reflection concerns both the theoretical and the experimental issues. Based on a literary review, fundamental arguments against the concept are summarized, and a synthesis of material objections is presented...
2017: Vnitr̆ní Lékar̆ství
https://www.readbyqxmd.com/read/28520199/economic-evaluation-of-strategies-for-restarting-anticoagulation-therapy-after-a-first-event-of-unprovoked-venous-thromboembolism
#13
M Monahan, J Ensor, D Moore, D Fitzmaurice, S Jowett
BACKGROUND: Following at least three months of anticoagulation therapy after a first unprovoked Venous Thromboembolism (VTE), there is uncertainty about the duration of therapy. Further anticoagulation therapy reduces the risk of having a potentially fatal recurrent VTE but at the expense of a higher risk of bleeding which can also be fatal. OBJECTIVE: An economic evaluation sought to estimate the long-term cost-effectiveness of using a decision rule for restarting anticoagulation therapy versus no extension of therapy in patients based on their risk of a further unprovoked VTE...
May 18, 2017: Journal of Thrombosis and Haemostasis: JTH
https://www.readbyqxmd.com/read/28508692/seifem-2010-e-economic-evaluation-of-posaconazole-for-antifungal-prophylaxis-in-patients-with-acute-myeloid-leukemia-receiving-induction-chemotherapy
#14
Alessandro Busca, Federica Lessi, Luisa Verga, Anna Candoni, Chiara Cattaneo, Simone Cesaro, Giulia Dragonetti, Mario Delia, Alessio De Luca, Gaspare Guglielmi, Mario Tumbarello, Giordana Martino, Gianpaolo Nadali, Rosa Fanci, Marco Picardi, Leonardo Potenza, Annamaria Nosari, Franco Aversa, Livio Pagano
Posaconazole demonstrated clinical superiority over fluconazole and itraconazole for prophylaxis of mold infections, although concerns exist regarding the high acquisition cost for posaconazole. In this respect, we sought to analyze the costs of antifungal prophylaxis in patients with acute myeloid leukemia (AML) who received prophylactic posaconazole (n = 510, 58%), itraconazole (n = 120, 14%) or fluconazole (n = 175, 20%) during induction chemotherapy. The estimated cost of antifungal prophylaxis as well as the costs of subsequent systemic antifungal therapy for treatening an invasive fungal infections (IFI) was higher in the posaconazole group compared to itraconazole and fluconazole groups...
May 16, 2017: Leukemia & Lymphoma
https://www.readbyqxmd.com/read/28507401/economic-evaluation-of-medicines
#15
REVIEW
Colman Taylor, Stephen Jan
No abstract text is available yet for this article.
April 2017: Australian Prescriber
https://www.readbyqxmd.com/read/28507369/nature-scope-and-use-of-economic-evaluation-of-healthcare-programmes-with-special-reference-to-pakistan
#16
Muhammad Ashar Malik, Saleem Perwaiz Iqbal, Farina Gul Abrejo
Economic evaluation (EE)/cost effectiveness analysis(CEA) of healthcare programmes is an emerging area, yet the resource base to apprehend EE/CEA is very limited in Pakistan. This paper attempts to fill this gap by providing a basic text in the field of EE with special reference to Pakistan. We used four dimensional criteria (available, relevant, complete and accurate) for reviewing the EE contents in the locally available textbooks and reading material on public health. We find CEA as core competency and skill of medical doctors in undergraduate medical curricula yet we could not find EE contents in the recommended textbooks...
May 2017: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/28504193/global-economic-evaluations-of-rotavirus-vaccines-a-systematic-review
#17
REVIEW
Surachai Kotirum, Naaon Vutipongsatorn, Khachen Kongpakwattana, Raymond Hutubessy, Nathorn Chaiyakunapruk
INTRODUCTION: World Health Organization (WHO) recommends Rotavirus vaccines to prevent and control rotavirus infections. Economic evaluations (EE) have been considered to support decision making of national policy. Summarizing global experience of the economic value of rotavirus vaccines is crucial in order to encourage global WHO recommendations for vaccine uptake. Therefore, a systematic review of economic evaluations of rotavirus vaccine was conducted. METHODS: We searched Medline, Embase, NHS EED, EconLit, CEA Registry, SciELO, LILACS, CABI-Global Health Database, Popline, World Bank - e-Library, and WHOLIS...
May 11, 2017: Vaccine
https://www.readbyqxmd.com/read/28503713/development-and-refinement-of-the-waite-a-new-obesity-specific-quality-of-life-measure-for-adolescents
#18
Yemi Oluboyede, Claire Hulme, Andrew Hill
BACKGROUND: Few weight-specific outcome measures, developed specifically for obese and overweight adolescents, exist and none are suitable for the elicitation of utility values used in the assessment of cost effectiveness. OBJECTIVES: The development of a descriptive system for a new weight-specific measure. METHODS: Qualitative interviews were conducted with 31 treatment-seeking (above normal weight status) and non-treatment-seeking (school sample) adolescents aged 11-18 years, to identify a draft item pool and associated response options...
May 13, 2017: Quality of Life Research
https://www.readbyqxmd.com/read/28500955/economic-evaluation-of-nurse-practitioner-and-clinical-nurse-specialist-roles-a-methodological-review
#19
Elena Lopatina, Faith Donald, Alba DiCenso, Ruth Martin-Misener, Kelley Kilpatrick, Denise Bryant-Lukosius, Nancy Carter, Kim Reid, Deborah A Marshall
BACKGROUND: Advanced practice nurses (e.g., nurse practitioners and clinical nurse specialists) have been introduced internationally to increase access to high quality care and to tackle increasing health care expenditures. While randomised controlled trials and systematic reviews have demonstrated the effectiveness of nurse practitioner and clinical nurse specialist roles, their cost-effectiveness has been challenged. The poor quality of economic evaluations of these roles to date raises the question of whether current economic evaluation guidelines are adequate when examining their cost-effectiveness...
May 4, 2017: International Journal of Nursing Studies
https://www.readbyqxmd.com/read/28499957/costs-of-outpatient-parenteral-antimicrobial-therapy-opat-administered-by-hospital-at-home-units-in-spain
#20
V J González-Ramallo, M Mirón-Rubio, A Mujal, O Estrada, C Forné, B Aragón, A J Rivera
The aim of this study was to assess the direct healthcare costs of outpatient parenteral antimicrobial therapy (OPAT) administered by hospital at home (HaH) units in Spain. An observational, multicentre, economic evaluation of retrospective cohorts was conducted. Patients were treated at home by the HaH units of three Spanish hospitals between January 2012 and December 2013. From the cost accounting of HaH OPAT (staff, pharmacy, transportation, diagnostic tests and structural), the cost of each outpatient course was obtained following a top-down strategy based on the use of resources...
May 9, 2017: International Journal of Antimicrobial Agents
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