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"Cost-utility"

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https://www.readbyqxmd.com/read/29149159/in-errata-cost-utility-analysis-of-lumbar-interlaminar-epidural-injections-in-the-treatment-of-lumbar-disc-herniation-central-spinal-stenosis-and-axial-or-discogenic-low-back-pain
#1
https://www.readbyqxmd.com/read/29147166/a-cost-utility-analysis-of-endovascular-aneurysm-repair-for-abdominal-aortic-aneurysm
#2
Yutaka Takayama
Objective: To assess medical economic adequacy of endovascular aneurysm repair (EVAR) for abdominal aortic aneurysm (AAA). Methods: Cost-utility analysis. A total of 21 patients with AAA treated at Ibaraki Prefectural Central Hospital in 2014 were divided into non-ruptured EVAR (Group E) and open surgery (OS) (Group O), and ruptured OS (Group R) groups, and hospital costs were aggregated with a medical accounting system. Mid-level hospital costs were estimated by a diagnosis-procedure-combination analysis system...
September 25, 2017: Annals of Vascular Diseases
https://www.readbyqxmd.com/read/29139314/cost-utility-analysis-of-life-long-prophylaxis-with-recombinant-factor-viii-fc-vs-recombinant-factor-viii-for-the-management-of-severe-haemophilia-a-in-sweden
#3
Nathaniel Henry, Jelena Jovanović, Max Schlueter, Persefoni Kritikou, Koo Wilson, Karl-Johan Myrén
AIMS: Prophylaxis with recombinant factor VIII (rFVIII) is the standard of care for severe haemophilia A in Sweden. The need for frequent injections with existing rFVIII products may, however, result in poor adherence to prophylaxis leading to increased bleeding and long-term joint damage. Recombinant FVIIIFc (rFVIIIFc) is an extended half-life fusion protein which can offer prolonged protection and reduced dosing frequency. The objective of this study was to evaluate the cost-utility of prophylaxis with rFVIIIFc in severe haemophilia A from the perspective of the Swedish health system...
November 15, 2017: Journal of Medical Economics
https://www.readbyqxmd.com/read/29129398/genomic-markers-in-prostate-cancer-decision-making
#4
REVIEW
Vito Cucchiara, Matthew R Cooperberg, Marc Dall'Era, Daniel W Lin, Francesco Montorsi, Jack A Schalken, Christopher P Evans
CONTEXT: Although the widespread use of prostate-specific antigen (PSA) has led to an early detection of prostate cancer (PCa) and a reduction of metastatic disease at diagnosis, PSA remains one of the most controversial biomarkers due to its limited specificity. As part of emerging efforts to improve both detection and management decision making, a number of new genomic tools have recently been developed. OBJECTIVE: This review summarizes the ability of genomic biomarkers to recognize men at high risk of developing PCa, discriminate clinically insignificant and aggressive tumors, and facilitate the selection of therapies in patients with advanced disease...
November 9, 2017: European Urology
https://www.readbyqxmd.com/read/29125514/crowdsourcing-utility-estimation-for-spina-bifida-in-the-general-population
#5
Ruiyang Jiang, Brian M Inouye, Hsin-Hsiao S Wang, Rohit Tejwani, Jonathan C Routh
INTRODUCTION: Cost-utility analyses (CUA) are useful when the treatment conditions depend on patient preferences that are in turn dependent on health state utility value. Spina bifida (SB) is an example of such a preference-sensitive condition. Historically, the SB utility value for CUA has been gathered via a traditional face-to-face interview. However, due to funding and time constrains, utility estimation via online crowdsourcing has recently gained popularity. Our aim was to estimate the utility value for a generic SB health state using a validated online tool...
November 3, 2017: Journal of Pediatric Rehabilitation Medicine
https://www.readbyqxmd.com/read/29122046/model-based-cost-effectiveness-of-conventional-and-innovative-chemo-radiation-in-lung-cancer
#6
Mathilda L Bongers, Dirk de Ruysscher, Cary Oberije, Philippe Lambin, Carin A Uyl-de Groot, José Belderbos, Veerle M H Coupé
INTRODUCTION: Optimizing radiotherapy with or without chemotherapy through advanced imaging and accelerated radiation schemes shows promising results in locally advanced non-small-cell lung cancer (NSCLC). This study compared the cost-effectiveness of positron emission tomography-computed tomography based isotoxic accelerated sequential chemo-radiation (SRT2) and concurrent chemo-radiation with daily low-dose cisplatin (CRT2) with standard sequential (SRT1) and concurrent chemo-radiation (CRT1)...
November 10, 2017: International Journal of Technology Assessment in Health Care
https://www.readbyqxmd.com/read/29121194/cost-effectiveness-of-colchicine-treatment-on-post-operative-atrial-fibrillation-poaf-events-in-patients-of-major-cardiac-surgery
#7
M Barman, Mahmoud Tantawy, Mark Sopher, Carsten Lennerz
Background: Post-operative atrial fibrillation (POAF) occurs in 20-50% of patients amid post-operative stay after Cardiac Surgery. We intend to determine whether colchicine therapy in patients undergoing cardiac surgery is a cost-effective strategy for prevention of postoperative atrial fibrillation. To undertake cost utility analysis and calculate ICUR for colchicine therapy in these subgroup of patients. Design: Decision tree model to calculate the incremental cost utility ratio comparing two treatment strategies in patients undergoing cardiac surgery...
November 7, 2017: European Heart Journal. Quality of Care & Clinical Outcomes
https://www.readbyqxmd.com/read/29119006/cost-utility-of-cobra-light-versus-cobra-therapy-in-patients-with-early-rheumatoid-arthritis-the-cobra-light-trial
#8
Marieke M Ter Wee, Veerle Mh Coupé, Debby den Uyl, Birgit S Blomjous, Esmee Kooijmans, Pit Jsm Kerstens, Mike T Nurmohamed, Dirkjan van Schaardenburg, Alexandre E Voskuyl, Maarten Boers, Willem F Lems
Objective: To evaluate if COmbinatie therapie Bij Reumatoïde Artritis (COBRA)-light therapy is cost-effective in treating patients with early rheumatoid arthritis (RA) compared with COBRA therapy. Methods: This economic evaluation was performed next to the open-label, randomised non-inferiority COBRA-light trial in 164 patients with early RA. Non-responders to COBRA or COBRA-light received etanercept (50 mg/week) for 3-6 months. The societal perspective analysis took medical direct, non-medical direct and indirect costs into account...
2017: RMD Open
https://www.readbyqxmd.com/read/29103751/cost-effectiveness-of-nivolumab-for-recurrent-or-metastatic-head-and-neck-cancer%C3%A2
#9
Matthew C Ward, Chirag Shah, David J Adelstein, Jessica L Geiger, Jacob A Miller, Shlomo A Koyfman, Mendel E Singer
OBJECTIVE: Nivolumab is the first drug to demonstrate a survival benefit for platinum-refractory recurrent or metastatic head and neck cancer. We performed a cost-utility analysis to assess the economic value of nivolumab as compared to alternative standard agents in this context. MATERIALS AND METHODS: Using data from the CheckMate 141 trial, we constructed a Markov simulation model from the US payer's perspective to evaluate the cost-effectiveness of nivolumab compared to physician choice of either cetuximab, methotrexate or docetaxel...
November 2017: Oral Oncology
https://www.readbyqxmd.com/read/29100609/economic-evaluations-of-alcohol-prevention-interventions-is-the-evidence-sufficient-a-review-of-methodological-challenges
#10
REVIEW
Sarah R Hill, Luke Vale, David Hunter, Emily Henderson, Yemi Oluboyede
Public health interventions have unique characteristics compared to health technologies, which present additional challenges for economic evaluation (EE). High quality EEs that are able to address the particular methodological challenges are important for public health decision-makers. In England, they are even more pertinent given the transition of public health responsibilities in 2013 from the National Health Service to local government authorities where new agents are shaping policy decisions. Addressing alcohol misuse is a globally prioritised public health issue...
October 27, 2017: Health Policy
https://www.readbyqxmd.com/read/29099409/cost-effectiveness-of-primary-and-revision-surgery-for-adult-spinal-deformity
#11
Tina Raman, Suresh K Nayar, Shuiqing Liu, Skolasky L Richard, Khaled M Kebaish
STUDY DESIGN: Retrospective comparative study. OBJECTIVE: The purpose of this study is to compare functional outcomes, hospital resource utilization, and spine-related costs during 2 years in patients who had undergone primary or revision surgery for adult spinal deformity (ASD). SUMMARY OF BACKGROUND DATA: After surgery for ASD, patients may require revision for pseudarthrosis, implant complications, or deformity progression. Data evaluating cost-effectiveness of primary and, in particular, revision surgery, for ASD are sparse...
November 2, 2017: Spine
https://www.readbyqxmd.com/read/29081998/assessing-value-for-money-in-maternal-and-newborn-health
#12
REVIEW
Aduragbemi Banke-Thomas, Barbara Madaj, Shubha Kumar, Charles Ameh, Nynke van den Broek
Responding to increasing demands to demonstrate value-for-money (VfM) for maternal and newborn health interventions, and in the absence of VfM analysis in peer-reviewed literature, this paper reviews VfM components and methods, critiques their applicability, strengths and weakness and proposes how VfM assessments can be improved. VfM comprises four components: economy, efficiency, effectiveness and cost-effectiveness. Both 'economy' and 'efficiency' can be assessed with detailed cost analysis utilising costs obtained from programme accounting data or generic cost databases...
2017: BMJ Global Health
https://www.readbyqxmd.com/read/29081416/cost-utility-of-using-alzheimer-s-disease-biomarkers-in-cerebrospinal-fluid-to-predict-progression-from-mild-cognitive-impairment-to-dementia
#13
Ron L H Handels, Anders Wimo, Richard Dodel, Milica G Kramberger, Pieter Jelle Visser, José Luis Molinuevo, Frans R J Verhey, Bengt Winblad
BACKGROUND: Diagnostic research criteria for Alzheimer's disease support the use of biomarkers in the cerebrospinal fluid (CSF) to improve the accuracy of the prognosis regarding progression to dementia for people with mild cognitive impairment (MCI). OBJECTIVE: The aim of this study was to estimate the potential incremental cost-effectiveness ratio of adding CSF biomarker testing to the standard diagnostic workup to determine the prognosis for patients with MCI...
October 21, 2017: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/29079947/the-cost-and-cost-utility-of-three-public-health-hiv-case-finding-strategies-evidence-from-rhode-island-2012-2014
#14
Xinqi C Li, Lillian Kusi, Theodore Marak, Thomas Bertrand, Philip A Chan, Omar Galárraga
To evaluate three testing strategies to identify new HIV diagnoses in Rhode Island (RI). RI deployed three testing strategies, by using rapid HIV tests at clinical settings, community-based organization (CBO) settings, and the Partner Notification Services (PNS) program from 2012 to 2014. We reviewed the rapid HIV test results and confirmatory test results to identify new diagnoses, and conducted a cost-utility analysis. The average cost per new diagnosis was $33,015 at CBO settings, $5446 at clinical settings, and $33,818 at the PNS program...
October 27, 2017: AIDS and Behavior
https://www.readbyqxmd.com/read/29079605/cost-effectiveness-of-the-faecal-immunochemical-test-at-a-range-of-positivity-thresholds-compared-with-the-guaiac-faecal-occult-blood-test-in-the-nhs-bowel-cancer-screening-programme-in-england
#15
Jacqueline Murphy, Stephen Halloran, Alastair Gray
OBJECTIVES: Through the National Health Service (NHS) Bowel Cancer Screening Programme (BCSP), men and women in England aged between 60 and 74 years are invited for colorectal cancer (CRC) screening every 2 years using the guaiac faecal occult blood test (gFOBT). The aim of this analysis was to estimate the cost-utility of the faecal immunochemical test for haemoglobin (FIT) compared with gFOBT for a cohort beginning screening aged 60 years at a range of FIT positivity thresholds. DESIGN: We constructed a cohort-based Markov state transition model of CRC disease progression and screening...
October 27, 2017: BMJ Open
https://www.readbyqxmd.com/read/29078880/impact-of-complications-on-length-of-stay-in-elective-laparoscopic-colectomies
#16
Mary Megan Mrdutt, Claire L Isbell, J Scott Thomas, Courtney N Shaver, Rahila Essani, Rajalakshmi Warrier, Harry Troy Papaconstantinou
BACKGROUND: Length of hospital stay (LOS) is an indirect measure of surgical quality and a surrogate for cost. The impact of postoperative complications on LOS following elective colorectal surgery is not well defined. The purpose of this study is to determine the contribution of specific complications towards LOS in elective laparoscopic colectomy patients. MATERIALS AND METHODS: American College of Surgeon's National Surgical Quality Improvement Program database (2011-2014) was queried for patients undergoing elective laparoscopic partial colectomy with primary anastomosis...
November 2017: Journal of Surgical Research
https://www.readbyqxmd.com/read/29075576/cost-benefits-of-rapid-recanalization-using-intraarterial-thrombectomy
#17
Hye Seon Jeong, Jong Wook Shin, Hyon-Jo Kwon, Hyeon-Song Koh, Hae-Sung Nam, Hee Seon Yu, Na Young Yoon, Jei Kim
OBJECTIVES: Thrombolytic therapy is associated with favorable clinical outcomes after successful and rapid recanalization in patients with acute ischemic stroke. This study aimed to evaluate the cost benefits and clinical outcomes at 1 year after intraarterial thrombectomy (IAT) by the rapidity of the successful recanalization. MATERIALS & METHODS: Clinical outcomes of and medical costs incurred by 230 patients with acute ischemic stroke who underwent IAT were compared by the rapidity from symptom onset to successful recanalization (2b/3 thrombolysis in cerebral infarction grade): ≤6-hr (n = 143), >6-hr (n = 31), and no-recanalization (n = 56)...
October 2017: Brain and Behavior
https://www.readbyqxmd.com/read/29073989/drug-policy-in-the-czech-republic
#18
Jana Skoupá
BACKGROUND: The legal background of the current pharmaceutical pricing and reimbursement (P&R) setting in the Czech Republic is based on Act 48/1997. Since 2008, the P&R process has been coordinated by the State Institute for Drug Control, which is the main stakeholder in the decision-making process; marketing authorization holders and insurance funds (IFs) also participate. OBJECTIVES: To present a general overview of the current Czech health care system and its P&R principles...
September 2017: Value in Health Regional Issues
https://www.readbyqxmd.com/read/29067906/the-age-of-blood-evaluation-able-randomised-controlled-trial-description-of-the-uk-funded-arm-of-the-international-trial-the-uk-cost-utility-analysis-and-secondary-analyses-exploring-factors-associated-with-health-related-quality-of-life-and-health-care-costs
#19
Timothy S Walsh, Simon Stanworth, Julia Boyd, David Hope, Sue Hemmatapour, Helen Burrows, Helen Campbell, Elena Pizzo, Nicholas Swart, Stephen Morris
BACKGROUND: At present, red blood cells (RBCs) are stored for up to 42 days prior to transfusion. The relative effectiveness and safety of different RBC storage times prior to transfusion is uncertain. OBJECTIVE: To assess the clinical effectiveness and cost-effectiveness of transfusing fresher RBCs (stored for ≤ 7 days) compared with current standard-aged RBCs in critically ill patients requiring blood transfusions. DESIGN: The international Age of BLood Evaluation (ABLE) trial was a multicentre, randomised, blinded trial undertaken in Canada, the UK, the Netherlands and France...
October 2017: Health Technology Assessment: HTA
https://www.readbyqxmd.com/read/29067633/implementation-of-continuous-video-electroencephalography-at-a-community-hospital-enhances-care-and-reduces-costs
#20
Brad J Kolls, Brian E Mace, Keith E Dombrowski
BACKGROUND: Despite data indicating the importance of continuous video-electroencephalography (cvEEG) monitoring, adoption has been slow outside major academic centers. Barriers to adoption include the need for technologists, equipment, and cvEEG readers. Advancements in lower-cost lead placement templates and commercial systems with remote review may reduce barriers to allow community centers to implement cvEEG. Here, we report our experience, lessons learned, and financial impact of implementing a community hospital cvEEG-monitoring program...
October 24, 2017: Neurocritical Care
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