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Victor H Molina-Lopez, Ismael Ortiz-Cartagena, Josue Mercado-Crespo, Miguel A Campos-Esteve
Transcatheter aortic valve replacement (TAVR) has increasingly become a fundamental approach for treating aortic valve stenosis (AVS), especially in high surgical risk patients. This case study underscores the criticality of meticulous procedural planning and precise valve selection in patients with severe AVS compounded by obesity. We report a case of a patient who, after receiving a 26 mm Edwards Sapiens 3 valve, presented with worsening exertional dyspnea and a declining indexed effective orifice area (EOAi)...
January 2024: Curēus
#22
Heberto Aquino-Bruno, Roberto Muratalla-González, Juan F Garcia-Garcia, José L Triano-Doroteo, Kevin Felix Rivera, Gerardo Carreon Balcarcel, Marisol Navarrete-Osuna
BACKGROUND: The presence of severe aortic stenosis in quadricuspid aortic valve (QAV) is an extremely rare combination, and it is unknown whether transcatheter aortic valve replacement (TAVR) is a safe option due to the low incidence. CASE SUMMARY: We present two patients diagnosed with severe aortic stenosis with QAV morphology type 1 (Nakamura classification). All patients presented to our hospital for evaluation because of worsening functional class, dyspnoea, or syncope...
February 2024: European Heart Journal. Case Reports
#23
Aljona Friedrich, Miralem Pasic, Volkmar Falk
No abstract text is available yet for this article.
February 2024: European Heart Journal. Case Reports
#24
REVIEW
Yoshiyuki Kagiyama, Damien Kenny, Ziyad M Hijazi
Various transcatheter interventions for the right ventricular outflow tract (RVOT) have been introduced and developed in recent decades. Transcatheter pulmonary valve perforation was first introduced in the 1990s. Radiofrequency wire perforation has been the approach of choice for membranous pulmonary atresia in newborns, with high success rates, although complication rates remain relatively common. Stenting of the RVOT is a novel palliative treatment that may improve hemodynamics in neonatal patients with reduced pulmonary blood flow and RVOT obstruction...
January 3, 2024: Global Cardiology Science & Practice
#25
JOURNAL ARTICLE
Marianna Adamo, Luca Branca, Elisa Pezzola, Francesco Saia, Thomas Pilgrim, Mohamed Abdel-Wahab, Philippe Garot, Caterina Gandolfo, Claudia Fiorina, Sofia Sammartino, Azeem Latib, Ignacio Amat Santos, Darren Mylotte, Federico De Marco, Ole De Backer, Luis Nombela Franco, Mariama Akodad, Flavio Luciano Ribichini, Francesco Bedogni, Giulia Laterra, Alessandro Mazzapicchi, Daijiro Tomii, Pietro Laforgia, Stefano Cannata, Andrea Scotti, Simone Fezzi, Enrico Criscione, Enrico Poletti, Mattia Mazzucca, Roberto Valvo, MattiaLunardi, Andrea Mainardi, Stefano Andreaggi, Angelo Quagliana, Nicholas Montarello, Breda Hennessey, Matias Mon-Noboa, David Meier, Carmelo Sgroi, Claudia Maria Reddavid, Orazio Strazzieri, Silvia Crescenzia Motta, Valentina Frittitta, Elena Dipietro, Alessandro Comis, Chiara Melfa, Mariachiara Calì, Holger Thiele, John G Webb, Lars Sondergaard, Corrado Tamburino, Marco Metra, Giuliano Costa, Marco Barbanti
Evidence regarding sex-related differences in response to transcatheter aortic valve implantation according to the valve type is lacking. This study sought to evaluate the impact of sex on the treatment effect of Evolut-PRO/PRO+ (PRO) or Sapien 3 Ultra (ULTRA) devices on clinical outcomes. Comparative Analysis of Evolut PRO vs Sapien 3 Ultra Valves for Transfemoral Transcatheter Aortic Valve Implantation (OPERA-TAVI) is a multicenter multinational registry including patients undergoing latest-iteration PRO or ULTRA implantation...
February 22, 2024: American Journal of Cardiology
#26
JOURNAL ARTICLE
Syeda A Hasan, Moustafa Morsi, Belinda S Frakes, Marien E Bryson, Christian W Schmidt, Puvi Seshiah, Joseph Choo, J Michael Smith, Geoffrey A Answini, Terri L Stewart-Dehner, Senan J Yasar, James G Jollis, Mark D Berlacher, Teresa M Ratajczak, Eugene S Chung, Dean J Kereiakes, Santiago Garcia
BACKGROUND: Transcatheter mitral valve replacement (TMVR) faces anatomical challenges, currently limiting widespread adoption. OBJECTIVES: To describe the natural history and prognosis of patients ineligible for various TMVR devices. METHODS: During a 4-year period (2019-2023) 3 TMVR devices (SAPIEN M3, Intrepid and Alta Valve) became available at a single institution (The Christ Hospital, Cincinnati, OH) in the setting of pivotal clinical trials or early feasibility study...
February 10, 2024: Cardiovascular Revascularization Medicine: Including Molecular Interventions
#27
JOURNAL ARTICLE
Wissam Harmouch, Barbara Karnkowska, Ravi Thakker, Peter Rasmussen, Mostafa Shalaby, Wissam Khalife, Haider Alwash, Afaq Motiwala, Paul Kumfa, Syed Gilani, Hani Jneid, Umamahesh Rangasetty
INTRODUCTION: Transcatheter aortic valve implantation (TAVI) plays a vital role in patients with symptomatic aortic stenosis. Despite the mortality benefit of TAVI, embolic stroke remains a feared complication. As a result, transcatheter cerebral embolic protection (TCEP) devices have been developed to reduce this risk. Given the ongoing debate of TCEP in TAVI, we performed a systematic review and meta-analysis of all randomized controlled trials to date to identify outcomes of periprocedural stroke using the Sentinel™ cerebral protection system (CPS)...
February 10, 2024: Cardiology and Therapy
#28
JOURNAL ARTICLE
Brennan J Vogl, Alejandra Chavez-Ponce, Adam Wentworth, Eric Erie, Pradeep Yadav, Vinod H Thourani, Lakshmi Prasad Dasi, Brian Lindman, Mohamad Alkhouli, Hoda Hatoum
BACKGROUND: The cause for the association between increased cardiovascular mortality rates and lower blood pressure (BP) after aortic valve replacement (AVR) is unclear. This study aims to assess how the epicardial coronary flow (ECF) after AVR varies as BP levels are changed in the presence of a right coronary lesion. METHODS: The hemodynamics of a 3D printed aortic root model with a SAPIEN 3 26 deployed were evaluated in an in vitro left heart simulator under a range of varying systolic blood pressure (SBP) and diastolic blood pressure (DBP)...
January 2024: Structural heart: the journal of the Heart Team
#29
JOURNAL ARTICLE
Rayan S El-Zein, Ali O Malik, David J Cohen, John A Spertus, John T Saxon, Philippe Pibarot, Rebecca T Hahn, Maria C Alu, Kan Shang, Susheel K Kodali, Vinod H Thourani, Martin B Leon, Michael J Mack, Adnan K Chhatriwalla
BACKGROUND: Baseline left ventricular diastolic dysfunction (LVDD) is associated with poor health status in patients with severe aortic stenosis undergoing transcatheter aortic valve replacement (TAVR), but health status improvement after TAVR appears similar across all grades of LVDD. Here, we aim to examine the relationship between changes in LVDD severity and health status outcomes following TAVR. METHODS: Patients who underwent TAVR and had evaluable LVDD at both baseline and 1 year in the PARTNER (Placement of Aortic Transcatheter Valves) 2 SAPIEN 3 registries and PARTNER 3 trial were analyzed...
January 2024: Structural heart: the journal of the Heart Team
#30
JOURNAL ARTICLE
Alexander C Egbe, Abdalla A Salama, William R Miranda, Snigdha Karnakoti, Jason H Anderson, C Charles Jain, Luke J Burchill, Heidi M Connolly
BACKGROUND: There are limited data about postprocedural right heart reverse remodeling and long-term prosthesis durability after transcatheter pulmonary valve replacement (TPVR) and how these compare to surgical pulmonary valve replacement (SPVR). OBJECTIVES: This study sought to compare right heart reverse remodeling, pulmonary valve gradients, and prosthetic valve dysfunction after TPVR vs SPVR. METHODS: Patients with TPVR were matched 1:2 to patients with SPVR based on age, sex, body surface area, congenital heart lesion, and procedure year...
January 22, 2024: JACC. Cardiovascular Interventions
#31
EDITORIAL
Sébastien Hascoet, Clément Karsenty, Alain Fraisse
No abstract text is available yet for this article.
January 22, 2024: JACC. Cardiovascular Interventions
#32
JOURNAL ARTICLE
Ada C Stefanescu Schmidt, Aimee K Armstrong, Jamil A Aboulhosn, Kevin F Kennedy, Thomas K Jones, Daniel S Levi, Doff B McElhinney, Ami B Bhatt
BACKGROUND: Transcatheter pulmonary valve replacement (TPVR) has expanded and evolved since its initial commercial approval in the United States in 2010. OBJECTIVES: This study sought to characterize real-world practice, including patient selection, procedural outcomes, complications, and off-label usage. METHODS: Characteristics and outcomes for patients undergoing balloon-expandable TPVR were collected from the American College of Cardiology National Cardiovascular Data Registry IMPACT (Improving Pediatric and Adult Congenital Treatment) Registry...
January 22, 2024: JACC. Cardiovascular Interventions
#33
Abderrahim Sanoussi, Adel Aminian, Jâd Abi-Khalil
The management of patients with severe aortic valve stenosis and an abdominal aortic aneurysm is a real therapeutic challenge. Minimally invasive treatment is more beneficial than open surgery for treating both aortic valve stenosis and abdominal aortic aneurysm. We present a case of a 77-year-old male initially treated with a 26 mm Sapien 3 transcatheter aortic valve replacement. Subsequently, using the same femoral access points, a custom fenestrated endoprosthesis and stents in digestive trunks and renal arteries were implanted...
March 2024: Radiology Case Reports
#34
JOURNAL ARTICLE
Nidal Jammoul, Valentin Dupasquier, Mariama Akodad, Pierre-Alain Meunier, Lionel Moulis, Sonia Soltani, Jean-Christophe Macia, Pierre Robert, Laurent Schmutz, Matthieu Steinecker, Christophe Piot, Frederic Targosz, Henri Benkemoun, Benoît Lattuca, François Roubille, Guillaume Cayla, Florence Leclercq
BACKGROUND: Safety and feasibility of transcatheter aortic valve replacement (TAVR) without balloon aortic valvuloplasty (BAV) using the SAPIEN 3 balloon-expandable device has been previously demonstrated. The impact on long-term valve hemodynamic performances and outcomes remains however unknown. We evaluate long-term clinical and hemodynamic results according to the implant strategy (direct TAVR versus BAV pre TAVR) in patients included in the DIRECTAVI randomized trial (NCT02729519)...
January 20, 2024: American Heart Journal
#35
JOURNAL ARTICLE
Hiroki A Ueyama, Adam B Greenbaum, Joe X Xie, Nikoloz Shekiladze, Patrick T Gleason, Isida Byku, Chandan M Devireddy, George S Hanzel, Peter C Block, Vasilis C Babaliaros
BACKGROUND: Transcatheter closure of transcatheter heart valve (THV)-related paravalvular leak (PVL) is associated with a high failure rate with available devices due to the complex interaction of THV and aortic/mitral annulus. OBJECTIVES: This study reports novel transcatheter techniques to treat PVL after THV. METHODS: We describe consecutive patients who underwent PVL closure after transcatheter aortic valve replacement (TAVR) or transcatheter mitral valve replacement (TMVR)...
January 9, 2024: JACC. Cardiovascular Interventions
#36
JOURNAL ARTICLE
Norihisa Miyawaki, Kenichi Ishizu, Shinichi Shirai, Kenji Nakano, Tadatomo Fukushima, Euihong Ko, Yasuo Tsuru, Hiroaki Tashiro, Miho Nakamura, Hiroyuki Tabata, Toru Morofuji, Takashi Morinaga, Masaomi Hayashi, Akihiro Isotani, Nobuhisa Ohno, Shinichi Kakumoto, Kenji Ando
BACKGROUND: In the Asian cohort, data are limited on the risk for coronary obstruction due to sinus of Valsalva (SOV) sequestration in redo transcatheter aortic valve replacement (TAVR) procedures. OBJECTIVES: The aim of this study was to assess the potential risk for coronary obstruction in simulated redo TAVR in Asian patients. METHODS: Post-TAVR computed tomographic data from 788 patients who received balloon-expandable (BE) SAPIEN 3 transcatheter aortic valves (TAVs) and 334 patients who received self-expanding (SE) Evolut R or Evolut PRO TAVs were analyzed...
January 2024: JACC Asia
#37
JOURNAL ARTICLE
Nathan El Bèze, Dominique Himbert, Gaspard Suc, Eric Brochet, Nadine Ajzenberg, Audrey Cailliau, John Kikoïne, Clemence Delhomme, Jose Luis Carrasco, Phalla Ou, Bernard Iung, Marina Urena
BACKGROUND: There is currently no established recommendation for antithrombotic treatment following transcatheter mitral valve replacement (TMVR). However, based on the analogy with surgical mitral bioprosthesis, vitamin K antagonists (VKAs) are predominantly used. OBJECTIVES: The purpose of this study was to compare bleeding and thrombotic events associated with direct oral anticoagulants (DOACs) or VKAs in a prospective cohort of TMVR patients. METHODS: We enrolled consecutive patients who underwent transseptal TMVR using a SAPIEN family prosthesis at our center between 2011 and 2023...
January 16, 2024: Journal of the American College of Cardiology
#38
JOURNAL ARTICLE
Brennan Vogl, Agata Sularz, Scott Lilly, Vinod H Thourani, Brian R Lindman, Mohamad Alkhouli, Hoda Hatoum
Coexisting hypertension and aortic stenosis are common. Some studies showed that elevated blood pressures may be associated with progression of calcific aortic valve disease (CAVD) while others showed no correlation. Flow dynamics in the sinuses of Valsalva are considered key factors in the progression of CAVD. While the relationship between hemodynamics and CAVD is not yet fully understood, it has been demonstrated that they are tightly correlated. This study aims to investigate the effect of changing systolic and diastolic blood pressures (SBP and DBP, respectively) on sinus hemodynamics in relation to potential initiation or progression of CAVD after aortic valve replacement (AVR)...
December 29, 2023: Annals of Biomedical Engineering
#39
JOURNAL ARTICLE
Ali Houeijeh, Clément Karsenty, Nicolas Combes, Clément Batteux, Florence Lecerf, Frederic Remy, Estibaliz Valdeolmillos, Jérôme Petit, Sébastien Hascoet
INTRODUCTION: Percutaneous pulmonary valve implantation (PPVI) with a SAPIEN 3 valve is effective for treating treat right ventricle outflow (RVOT) dysfunction. A modified technique was developed without prestenting using a protective valve delivery method. We aimed to compare the procedural results of the modified technique group (MTG) to those of patients in a conventional technique group (CTG). METHODS: We designed a matched before-after study. All consecutive PPVI with SAPIEN 3 performed in the MTG over 9 months were matched, based on the RVOT type and size, to consecutive procedures performed previously with SAPIEN 3...
December 13, 2023: Journal of Clinical Medicine
#40
JOURNAL ARTICLE
Young Kyoung Sa, Ik Jun Choi, Kiyuk Chang, Byung-Hee Hwang, Woo-Baek Chung, Kwan Yong Lee, Eun-Ho Choo, Chan Jun Kim, Mahn Won Park, Yoon Seok Choi, Chul Soo Park, Ki Dong Yoo, Doo Soo Jeon, Min-Ho Oak, Jungkuk Lee, Dongwoo Kang
A few studies have reported comparative analysis of clinical outcomes between balloon-expandable valve (BEV) and self-expandable valve (SEV) after transcatheter aortic valve replacement (TAVR) in patients with severe aortic stenosis using newer-generation devices. However, they were mostly limited to short-term outcomes and Western populations. In the present study, data of patients with severe AS who underwent TAVR between March 2016 and December 2018 were obtained from the National Health Insurance Service in Korea...
December 16, 2023: American Journal of Cardiology
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