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https://www.readbyqxmd.com/read/28214795/pre-implantation-balloon-aortic-valvuloplasty-and-clinical-outcomes-following-transcatheter-aortic-valve-implantation-a-propensity-score-analysis-of-the-uk-registry
#1
Glen P Martin, Matthew Sperrin, Rodrigo Bagur, Mark A de Belder, Iain Buchan, Mark Gunning, Peter F Ludman, Mamas A Mamas
BACKGROUND: Aortic valve predilation with balloon aortic valvuloplasty (BAV) is recommended before transcatheter aortic valve implantation (TAVI), despite limited data around the requirement of this preprocedural step and the potential risks of embolization. This study aimed to investigate the trends in practice and associations of BAV on short-term outcomes in the UK TAVI registry. METHODS AND RESULTS: Eleven clinical endpoints were investigated, including 30-day mortality, myocardial infarction, aortic regurgitation, valve dysfunction, and composite early safety...
February 18, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/28209261/the-feasibility-of-transcatheter-aortic-valve-implantation-using-the-edwards-sapien-3-for-patients-with-severe-bicuspid-aortic-stenosis
#2
Takahide Arai, Thierry Lefèvre, Thomas Hovasse, Marie-Claude Morice, Mauro Romano, Hakim Benamer, Philippe Garot, Kentaro Hayashida, Erik Bouvier, Bernard Chevalier
BACKGROUND: There are currently only limited data focusing on transcatheter aortic valve implantation (TAVI) for bicuspid aortic valves (BAV) patients using the Edwards SAPIEN (Irvine, CA, USA) 3 (S3) valve. The aim of this study was to evaluate the feasibility and efficacy of TAVI using the S3 in patients with BAV. METHODS: A total of 153 TAVI cases performed with the S3 were included. BAV was detected by multidetector computed tomography (MDCT) in 10 (7%) patients...
February 10, 2017: Journal of Cardiology
https://www.readbyqxmd.com/read/28207437/lack-of-association-between-preoperative-statin-use-and-respiratory-and-neurologic-complications-after-cardiac-surgery
#3
Ryu Komatsu, Huseyin Oguz Yilmaz, Jing You, C Allen Bashour, Shobana Rajan, Edward G Soltesz, Daniel I Sessler, Alparslan Turan
BACKGROUND: Statins may reduce the risk of pulmonary and neurologic complications after cardiac surgery. METHODS: The authors acquired data for adults who had coronary artery bypass graft, valve surgery, or combined procedures. The authors matched patients who took statins preoperatively to patients who did not. First, the authors assessed the association between preoperative statin use and the primary outcomes of prolonged ventilation (more than 24 h), pneumonia (positive cultures of sputum, transtracheal fluid, bronchial washings, and/or clinical findings consistent with the diagnosis of pneumonia), and in-hospital all-cause mortality, using logistic regressions...
February 16, 2017: Anesthesiology
https://www.readbyqxmd.com/read/28186624/adverse-events-associated-with-antipsychotic-use-in-hospitalized-older-adults-after-cardiac-surgery
#4
Dae H Kim, Krista F Huybrechts, Elisabetta Patorno, Edward R Marcantonio, Yoonyoung Park, Raisa Levin, Abdurrahman Abdurrob, Brian T Bateman
OBJECTIVES: To evaluate in-hospital adverse events associated with typical and atypical antipsychotic medications (APMs) after cardiac surgery. DESIGN: Retrospective cohort study. SETTING: Nationwide inpatient database, 2003 to 14. PARTICIPANTS: Individuals (mean age 70) newly treated with oral atypical (n = 2,580) or typical (n = 1,126 APMs) after coronary artery bypass grafting or valve surgery (N = 3,706). MEASUREMENTS: In-hospital mortality, arrhythmia, pneumonia, use of brain imaging (surrogate for oversedation and neurological events), and length of stay after drug initiation RESULTS: In the propensity score-matched cohort, median treatment duration was 3 days (interquartile range (IQR) 1-6 days) for atypical APMs and 2 days (IQR 1-3 days) for typical APMs...
February 10, 2017: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/28162223/impact-of-subclinical-vascular-complications-detected-by-systematic-postprocedural-multidetector-computed-tomography-after-transcatheter-aortic-valve-implantation-using-balloon-expandable-edwards-sapien-xt-heart-valve
#5
Yuki Kakefuda, Kentaro Hayashida, Yoshitake Yamada, Fumiaki Yashima, Taku Inohara, Ryo Yanagisawa, Makoto Tanaka, Takahide Arai, Takashi Kawakami, Yuichiro Maekawa, Hikaru Tsuruta, Yuji Itabashi, Mitsushige Murata, Motoaki Sano, Kazuma Okamoto, Akihiro Yoshitake, Hideyuki Shimizu, Masahiro Jinzaki, Keiichi Fukuda
Complications after transcatheter aortic valve implantation (TAVI) remain an important issue. This study aimed to evaluate the impact of systematic postprocedural multidetector computed tomography (MDCT) to detect subclinical complications after TAVI. From October 2013 to August 2015, a total of 135 patients who underwent transfemoral TAVI (n = 116) or transapical TAVI (n = 19) with Sapien XT and MDCT preprocedure and postprocedure were enrolled. Postprocedural MDCT findings were compared with the preprocedural MDCT findings...
January 5, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/28159378/valve-in-valve-implantation-of-a-sapien-3-transcatheter-heart-valve-for-reduction-of-paravalvular-regurgitation-despite-optimal-placement-of-the-first-transcatheter-heart%C3%A2-valve
#6
Ayoub El Hammiri, Jeannot Potvin, Jean-François Gobeil, Nicolas Noiseux, Louis-Mathieu Stevens, Jean-Bernard Masson
Valve-in-valve implantation is generally successful in reducing paravalvular regurgitation (PVR) in cases in which the first transcatheter heart valve is deployed in a suboptimal location. We describe a case of severe PVR 2 months after implantation of a 26-mm Sapien XT valve (Edwards Lifesciences Inc, Irvine, CA) in the optimal location. Valve-in-valve implantation of a Sapien 3 valve (Edwards Lifesciences Inc), and enough left ventricular outflow tract tissue at the inflow edge the Sapien XT to appose the sealing cuff of the Sapien 3 combined for successful PVR treatment...
November 29, 2016: Canadian Journal of Cardiology
https://www.readbyqxmd.com/read/28145041/first-in-human-experience-of-a-new-self-expandable-percutaneous-pulmonary-valve-implantation-using-knitted-nitinol-wire-and-tri-leaflet-porcine-pericardial-valve-in-the-native-right-ventricular-outflow-tract
#7
Gi Beom Kim, Bo Sang Kwon, Hong Gook Lim
Balloon-expandable percutaneous pulmonary valve systems using the Melody and Edwards SAPIEN transcatheter heart valves have been increasingly used instead of surgically implantable pulmonary valves. However, limited patients with right ventricular outflow tract (RVOT) lesions are suitable candidates for percutaneous pulmonary valve implantation (PPVI) using these systems after surgical correction of tetralogy of Fallot. Therefore, larger self-expandable valved-stents are being developed for native RVOT lesions...
February 1, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/28137288/computer-based-comparison-of-different-methods-for-selecting-mitral-annuloplasty-ring-size
#8
Sameer Al-Maisary, Sandy Engelhardt, Bastian Graser, Ivo Wolf, Matthias Karck, Raffaele De Simone
BACKGROUND: Ring sizing for mitral valve annuloplasty is conventionally done intraoperatively using specific 'sizer' instruments, which are placed onto the valve tissue. This approach is barely reproducible since different sizing strategies have been established among surgeons. The goal of this study is to virtually apply different sizing methods on the basis of pre-repair echocardiography to find out basic differences between sizing strategies. METHODS: In three-dimensional echocardiographs of 43 patients, the mitral annulus and the contour of the anterior mitral leaflet were segmented using MITK Mitralyzer software...
January 30, 2017: Journal of Cardiothoracic Surgery
https://www.readbyqxmd.com/read/28134644/management-of-rhinophyma-outcomes-study-of-the-subunit-method
#9
Aladdin H Hassanein, Raj M Vyas, Jessica Erdmann-Sager, Edward J Caterson, Julian J Pribaz
BACKGROUND: Rhinophyma causes a nasal deformity and functional airway obstruction. Partial excision (eg, tangential) with secondary healing commonly removes hypertrophic soft tissues but does not improve nasal support. The subunit method for rhinophyma uses 6 nasal flaps to provide exposure for removal of rhinophymatous tissue and enhance structure. The purpose of this study was to evaluate outcomes of subunit method. METHODS: Medical records of patients with rhinophyma treated with the subunit method between 2013 and 2016 were analyzed...
January 27, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28132979/reducing-prosthesis-patient-mismatch-with-edwards-magna-prosthesis-for-aortic-valve-replacement
#10
Yuta Kume, Tomoyuki Fujita, Satsuki Fukushima, Hiroki Hata, Yusuke Shimahara, Yorihiko Matsumoto, Kizuku Yamashita, Junjiro Kobayashi
BACKGROUND: Prosthesis-patient mismatch (PPM) is associated with increased mid-term and long-term mortality rates after aortic valve replacement (AVR). This study aimed to evaluate the efficacy of the Carpentier-Edwards Perimount Magna and Magna Ease (CEPMs) aortic bioprostheses to reduce the incidence of PPM.Methods and Results:Altogether, 282 consecutive patients (113 women, mean age 69.9±9.9 years) underwent AVR with a CEPMs between 2008 and 2015. They were divided into 3 groups based on the risk of PPM as a result of their body surface area and aortic annular diameter (BSA/AnnD ratio): low-risk (LR) group: 0...
January 27, 2017: Circulation Journal: Official Journal of the Japanese Circulation Society
https://www.readbyqxmd.com/read/28131425/evaluation-of-hemodynamic-performance-of%C3%A2-aortic-valve-bioprostheses-in-a-model-of%C3%A2-oversizing
#11
John D Cleveland, Michael E Bowdish, Carol E Eberhardt, Wendy J Mack, James A Crabtree, Thomas A Vassiliades, Alan M Speir, Yogesh A Darekar, Amy E Hackmann, Vaughn A Starnes, Robbin G Cohen
BACKGROUND: The risk of patient-prosthesis mismatch drives most surgeons to select the largest bioprosthesis possible during aortic valve replacement, but interactions between the native aortic annulus and valve prosthesis remain poorly defined. We examined the hemodynamic and functional consequences of oversizing contemporary bioprostheses in an in vitro model. METHODS: Three sizes each (21, 23, and 25 mm) of 5 aortic bioprostheses (Magna, Edwards Lifesciences, Irvine, CA; Trifecta and Epic, St...
January 25, 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/28131332/late-breaking-trials-from-the-2016-american-heart-association-s-scientific-sessions
#12
REVIEW
Kyle D Buchanan, M Chadi Alraies, Alexandre H Kajita, Toby Rogers, Edward Koifman, Arie Steinvil
The late breaking trials released at the American Heart Association scientific sessions conference in November in New Orleans, LA covered a wide range of topics, including new devices within the field of heart failure, new registry data on transcatheter aortic valve replacement (TAVR) in intermediate risk patients, and medical management of peripheral arterial disease, coronary artery disease, and hypercholesterolemia. The following review highlights the late breaking trials presented at the conference that will have significant impact on clinical practice...
January 2017: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/28128540/determinants-of-aortic-regurgitation-after-transcatheter-aortic-valve-implantation-an-observational-study-using-multi-slice-computed-tomography-msct-guided-sizing
#13
Zouhair Rahhab, Nahid El Faquir, Ramón Rodríguez-Olivares, Claire Ren, Nicolas VAN Mieghem, Marcel L Geleijnse, Carl Schultz, Ron VAN Domburg, Peter P DE Jaegere
BACKGROUND: To explore the determinants of aortic regurgitation (AR) after transcatheter aortic valve implantation (TAVI) using Multi Slice Computed Tomography (MSCT) instead of echocardiography-guided sizing. METHODS: Determinants of AR were assessed in 313 consecutive patients who underwent TAVI with the Medtronic(MCS, n=259) or Edwards Sapien or XT(ESV, n=54) using MSCT- guided sizing. AR was assessed by angiography immediately after TAVI (n=313, Sellers) and by echocardiography at discharge (n=285, VARC-2)...
January 27, 2017: Journal of Cardiovascular Surgery
https://www.readbyqxmd.com/read/28123149/clinical-outcomes-and-bioprosthetic-valve-function-after-transcatheter-aortic-valve-implantation-under-dual-antiplatelet-therapy-vs-aspirin-alone
#14
Yasuhiro Ichibori, Isamu Mizote, Koichi Maeda, Toshinari Onishi, Tomohito Ohtani, Osamu Yamaguchi, Kei Torikai, Toru Kuratani, Yoshiki Sawa, Satoshi Nakatani, Yasushi Sakata
BACKGROUND: Dual antiplatelet therapy (DAPT) is commonly used after transcatheter aortic valve implantation (TAVI); however, the supporting evidence is limited. To determine if aspirin alone is a better alternative to DAPT, we compared the outcomes of patients treated with DAPT or aspirin alone after TAVI.Methods and Results:We analyzed a total of 144 consecutive patients (92 females, mean age 83±6 years) who underwent implantation of a balloon-expandable transcatheter valve (SAPIEN or SAPIEN XT, Edwards Lifesciences)...
January 24, 2017: Circulation Journal: Official Journal of the Japanese Circulation Society
https://www.readbyqxmd.com/read/28113458/marginal-space-deep-learning-efficient-architecture-for-volumetric-image-parsing
#15
Florin C Ghesu, Edward Krubasik, Bogdan Georgescu, Vivek Singh, Yefeng Zheng, Joachim Hornegger, Dorin Comaniciu
Robust and fast solutions for anatomical object detection and segmentation support the entire clinical workflow from diagnosis, patient stratification, therapy planning, intervention and follow-up. Current state-of-the-art techniques for parsing volumetric medical image data are typically based on machine learning methods that exploit large annotated image databases. There are two main challenges that need to be addressed, these are the efficiency in processing large volumetric input images and the need for strong, representative image features...
March 7, 2016: IEEE Transactions on Medical Imaging
https://www.readbyqxmd.com/read/28109558/choice-of-balloon-expandable-versus-self-expanding-transcatheter-aortic-valve-impacts-hemodynamics-differently-according-to-aortic-annular-size
#16
Toby Rogers, Arie Steinvil, Jiaxiang Gai, Rebecca Torguson, Edward Koifman, Sarkis Kiramijyan, Smita Negi, Sang Yeub Lee, Petros Okubagzi, Lowell F Satler, Itsik Ben-Dor, Augusto D Pichard, Ron Waksman
We sought to determine whether balloon-expandable valve (BEV) and self-expanding valve (SEV) affect valve hemodynamics differently according to native aortic annulus size. Transcatheter aortic valve replacement can achieve superior prosthetic valve hemodynamics compared with surgical aortic valve replacement, particularly in patients with small aortic annulus. One hundred ninety-three consecutive transcatheter aortic valve replacement patients were grouped into tertiles defined by computed tomography derived aortic annulus systolic perimeter...
December 18, 2016: American Journal of Cardiology
https://www.readbyqxmd.com/read/28108576/dual-source-computed-tomography-based-analysis-of-stent-performance-its-association-with-valvular-calcification-and-residual-aortic-regurgitation-after-implantation-of-a-balloon-expandable-transcatheter-heart-valve
#17
Julius Gerstmeyer, Maximilian Kütting, Buntaro Fujita, Annika Schuhbäck, Martin Arnold, Jochen Börgermann, Stephan Achenbach, Ulrich Steinseifer, Jan Gummert, Stephan Ensminger
OBJECTIVES: The aim of this study was to investigate the mutual influence of valvular calcifications and transcatheter aortic valve stent geometry during and after implantation of a balloon-expandable SAPIEN(®)/SAPIEN XT(®) prostheses. Aortic valve calcification has been linked with adverse complications after transcatheter aortic valve implantation (TAVI). However, little is known about the fate of the calcifications after TAVI as well as its influence on transcatheter heart valve geometry...
January 20, 2017: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/28108064/stent-and-leaflet-stresses-in-a-26-mm-first-generation-balloon-expandable-transcatheter-aortic-valve
#18
Yue Xuan, Kapil Krishnan, Jian Ye, Danny Dvir, Julius M Guccione, Liang Ge, Elaine E Tseng
OBJECTIVE: Transcatheter aortic valve replacement is established therapy for high-risk and inoperable patients with severe aortic stenosis, but questions remain regarding long-term durability. Valve design influences durability. Increased leaflet stresses in surgical bioprostheses have been correlated with degeneration; however, transcatheter valve leaflet stresses are unknown. From 2007 to 2014, a majority of US patients received first-generation balloon-expandable transcatheter valves...
December 23, 2016: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28106026/successful-simultaneous-ipsilateral-stenting-of-common-iliac-artery-stenosis-and-transfemoral-aortic-valve-replacement
#19
Abdullah Nabi Aslan, Hacı Ahmet Kasapkara, Serkan Sivri, Murat Can Güney, Engin Bozkurt
Transcatheter aortic valve replacement (TAVR) was designed to treat elderly patients with severe aortic stenosis at high risk for surgery, and is most commonly performed with retrograde approach through femoral arteries. However, in up to 30% of cases, it is either not possible to use this access route or it is considered to have high risk of vascular injury. Alternative approaches have been described for patients with no suitable femoral access: trans-subclavian, transaortic, or direct aortic access; however, since the introduction of new valves deployed with low-profile delivery systems, another alternative transcatheter approach has been discovered...
January 2017: Türk Kardiyoloji Derneği Arşivi: Türk Kardiyoloji Derneğinin Yayın Organıdır
https://www.readbyqxmd.com/read/28106001/impact-of-femoral-artery-puncture-using-digital-subtraction-angiography-and-road-mapping-on-vascular-and-bleeding-complications-after-transfemoral-transcatheter-aortic-valve-implantation
#20
Mohamed El-Mawardy, Bettina Schwarz, Martin Landt, Dmitriy Sulimov, Julia Kebernik, Abdelhakim Allali, Bjoern Becker, Ralph Toelg, Gert Richardt, Mohamed Abdel-Wahab
AIMS: The use of large-diameter sheaths carries the risk of significant vascular and bleeding complications after transfemoral transcatheter aortic valve implantation (TAVI). In this analysis, we sought to assess the impact of a modified femoral artery puncture technique using digital subtraction angiography (DSA) and road mapping during transfemoral TAVI on periprocedural vascular and bleeding events. METHODS AND RESULTS: This is a retrospective analysis of transfemoral TAVI patients included in a prospective institutional database...
January 20, 2017: EuroIntervention
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