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https://www.readbyqxmd.com/read/29462049/suprasternal-transcatheter-aortic-valve-replacement-in-patients-with-marginal-femoral-access
#1
Andy C Kiser, Thomas G Caranasos, Mark D Peterson, David M Holzhey, Philipp Kiefer, L Wiley Nifong, Michael A Borger
OBJECTIVE: Recently, the PARTNER 2A trial reported results of transcatheter aortic valve replacement versus surgical aortic valve replacement in 2032 intermediate-risk patients at 2 years. Two hundred thirty-six patients (24%) required an access route other than transfemoral. Compared with transfemoral and surgical aortic valve replacement, nontransfemoral transcatheter aortic valve replacement was associated with a numerically higher rate of death and disabling stroke at 30 days. This underscores the need for a better alternative surgical approach for patients with marginal femoral access...
February 17, 2018: Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery
https://www.readbyqxmd.com/read/29440625/safety-and-feasibility-of-a-novel-active-fixation-temporary-pacing-lead
#2
Mark Webster, Sanjeevan Pasupati, Nigel Lever, Martin Stiles
OBJECTIVE: This first-in-human study evaluated the safety and technical feasibility of the Tempo temporary cardiac pacing lead (BioTrace Medical), which includes a novel fixation mechanism and soft tip. BACKGROUND: Complications of temporary pacing leads include dislodgment, arrhythmias, and ventricular perforation. Temporary pacing applications have increased with transcatheter aortic valve replacement (TAVR) growth, for rapid pacing during balloon valvuloplasty (BAV) and valve deployment, and for periprocedural bradyarrhythmia support...
February 15, 2018: Journal of Invasive Cardiology
https://www.readbyqxmd.com/read/29429630/transcatheter-aortic-valve-replacement-in-patients-with-severe-mitral-or-tricuspid-regurgitation-at-extreme-risk-for-surgery
#3
Stephen H Little, Jeffrey J Popma, Neal S Kleiman, G Michael Deeb, Thomas G Gleason, Steven J Yakubov, Stan Checuti, Daniel O'Hair, Tanvir Bajwa, Mubashir Mumtaz, Brijeshwar Maini, Alan Hartman, Stanley Katz, Newell Robinson, George Petrossian, John Heiser, William Merhi, B Jane Moore, Shuzhen Li, David H Adams, Michael J Reardon
OBJECTIVES: Patients with symptomatic severe aortic stenosis and severe mitral regurgitation or severe tricuspid regurgitation were excluded from the major transcatheter aortic valve replacement trials. We studied these 2 subgroups in patients at extreme risk for surgery in the prospective, nonrandomized, single-arm CoreValve US Expanded Use Study. METHODS: The primary end point was all-cause mortality or major stroke at 1 year. A favorable medical benefit was defined as a Kansas City Cardiomyopathy Questionnaire overall summary score greater than 45 at 6 months and greater than 60 at 1 year and with a less than 10-point decrease from baseline...
January 31, 2018: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/29420704/pacemaker-implantation-rate-after-transcatheter-aortic-valve-implantation-with-early-and-new-generation-devices-a-systematic-review
#4
Philippe J van Rosendael, Victoria Delgado, Jeroen J Bax
Aims: The incidence of new-onset conduction abnormalities requiring permanent pacemaker implantation (PPI) after transcatheter aortic valve implantation (TAVI) with new-generation prostheses remains debated. This systematic review analyses the incidence of PPI after TAVI with new-generation devices and evaluates the electrical, anatomical, and procedural factors associated with PPI. In addition, the incidence of PPI after TAVI with early generation prostheses was reviewed for comparison...
February 6, 2018: European Heart Journal
https://www.readbyqxmd.com/read/29413244/long-term-outcomes-in-patients-with%C3%A2-new-permanent-pacemaker-implantation-following-transcatheter-aortic-valve-replacement
#5
Chekrallah Chamandi, Marco Barbanti, Antonio Munoz-Garcia, Azeem Latib, Luis Nombela-Franco, Enrique Gutiérrez-Ibanez, Gabriela Veiga-Fernandez, Asim N Cheema, Ignacio Cruz-Gonzalez, Vicenç Serra, Corrado Tamburino, Antonio Mangieri, Antonio Colombo, Pilar Jiménez-Quevedo, Jaime Elizaga, Gerard Laughlin, Dae-Hyun Lee, Bruno Garcia Del Blanco, Tania Rodriguez-Gabella, Josep-Ramon Marsal, Mélanie Côté, François Philippon, Josep Rodés-Cabau
OBJECTIVES: This study sought to evaluate the long-term clinical impact of permanent pacemaker implantation (PPI) after transcatheter aortic valve replacement (TAVR). BACKGROUND: Conduction disturbances leading to PPI are common following TAVR. However, no data exist regarding the impact of PPI on long-term outcomes post-TAVR. METHODS: This was a multicenter study including a total of 1,629 patients without prior PPI undergoing TAVR (balloon- and self-expandable valves in 45% and 55% of patients, respectively)...
February 12, 2018: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/29388705/echocardiography-in-transcatheter-aortic-valve-implantation-part-1-transthoracic-echocardiography
#6
REVIEW
Tasneem Z Naqvi
Transcatheter aortic valve replacement (TAVR) has been a revolutionary technique in the treatment of degenerative aortic valve stenosis. Selection of appropriate patients and appropriate valve size is crucial for improved patient outcome. Echocardiographic imaging is a critical component for patient selection and plays an important role in the selection of valve size, procedural guidance, and patient follow-up. This review discusses role of echocardiography in patient selection, device implantation, and postimplant follow-up for the first-generation CoreValve as used in pivotal trial...
February 1, 2018: Echocardiography
https://www.readbyqxmd.com/read/29386188/patient-specific-computer-simulation-to-elucidate-the-role-of-contact-pressure-in-the-development-of-new-conduction-abnormalities-after-catheter-based-implantation-of-a-self-expanding-aortic-valve
#7
Giorgia Rocatello, Nahid El Faquir, Gianluca De Santis, Francesco Iannaccone, Johan Bosmans, Ole De Backer, Lars Sondergaard, Patrick Segers, Matthieu De Beule, Peter de Jaegere, Peter Mortier
BACKGROUND: The extent to which pressure generated by the valve on the aortic root plays a role in the genesis of conduction abnormalities after transcatheter aortic valve replacement (TAVR) is unknown. This study elucidates the role of contact pressure and contact pressure area in the development of conduction abnormalities after TAVR using patient-specific computer simulations. METHODS AND RESULTS: Finite-element computer simulations were performed to simulate TAVR of 112 patients who had undergone TAVR with the self-expanding CoreValve/Evolut R valve...
February 2018: Circulation. Cardiovascular Interventions
https://www.readbyqxmd.com/read/29377318/trans-carotid-access-for-tavr-allows-safe-and-rapid-exchange-for-bailout-valve-in-valve-procedures
#8
Enrico Ferrari, Elena Caporali, Giovanni Pedrazzini, Stefanos Demertzis
Trans-carotid access for trans-catheter aortic valve replacement is a valid alternative in patients with aortic valve dysfunction, severe peripheral vascular disease, and high-risk for surgery. However, in the event of the need for a bailout valve-in-valve procedure, the safety of this access site is uncertain. We report a patient with aortic regurgitation, previous coronary surgery, peripheral vascular disease, and impaired ventricular function who underwent a CoreValve Evolut-R (Medtronic Inc, Minneapolis, MN) implantation through the left carotid artery followed by a successful valve-in-valve procedure with a 26-mm Edwards Sapien3 valve (Edwards Lifesciences, Irvine, CA) through the same carotid access site...
January 28, 2018: Journal of Cardiac Surgery
https://www.readbyqxmd.com/read/29352701/bailout-surgical-explantation-of-a-transcatheter-valve-in-valve-for-subacute-thrombosis-when-there-is-no-time-for-anticoagulation-case-report-and-literature-review
#9
Francesco Notaristefano, Matteo Rocco Reccia, Salvatore Notaristefano, Roberto Annunziata, Rocco Sclafani, Giuseppe Ambrosio, Claudio Cavallini
Trancatheter heart valve (THV) thrombosis is effectively treated with anticoagulation but alternative therapies are required when a faster gradient reduction is needed. Open heart surgery has been rarely performed due to the high perioperative mortality and only five cases have been described so far. Here we describe a case of emergent surgical explantation for THV thrombosis after a valve-in-valve. A 67years old man underwent transcatheter aortic valve implantation for a failed surgical bioprosthesis Epic 21mm (St...
December 13, 2017: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/29329825/effectiveness-and-safety-of-transcatheter-aortic-valve-implantation-in-patients-with-pure-aortic-regurgitation-and-advanced-heart-failure
#10
Gabriele Pesarini, Mattia Lunardi, Anna Piccoli, Leonardo Gottin, Daniele Prati, Valeria Ferrero, Roberto Scarsini, Aldo Milano, Alberto Forni, Giuseppe Faggian, Flavio Ribichini
Results of transcatheter aortic valve implantation (TAVI) for treatment of severe noncalcific isolated aortic regurgitation (AR) complicated by advanced heart failure or cardiogenic shock has been previously reported only in isolated case reports. Current self-expanding transcatheter aortic valves are designed to treat aortic valve stenosis, and have also been implanted in cases of severe AR due to degenerated bioprosthesis and in very few cases of native aortic valves. We report 13 consecutive inoperable patients with noncalcific, pure AR, and advanced heart failure treated with emergency percutaneous transfemoral implantation with self-expandable CoreValves at our institution between July 2012 and September 2017...
December 11, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/29302939/transcatheter-aortic-valve-implantation-in-high-risk-inoperable-patients-repositionable-versus-non-repositionable-self-expanding-valve
#11
Verena Veulemans, Dagmar B Sötemann, Laura Kleinebrecht, Stefanie Keymel, Christian Jung, Tobias Zeus, Malte Kelm, Ralf Westenfeld
BACKGROUND: Although next-generation cardiac prostheses have shown favorable results in transcatheter aortic valve implantation (TAVI), these have mostly been documented in intermediate-risk patients. Whether this could be translated to high-risk patients is not known. Hence, the safety and clinical performance of the new, repositionable CoreValve Evolut R-System (ERS) was evaluated by comparison with a non-repositionable CoreValve-System (CVS), in 96 high-risk/inoperable (HRI) patients...
July 2017: Journal of Heart Valve Disease
https://www.readbyqxmd.com/read/29251657/transcatheter-aortic-valve-replacement-optimizing-outcomes-for-healthy-recovery
#12
Kashish Goel, David R Holmes
Transcatheter aortic valve replacement (TAVR) has been approved in the United States for intermediate and high-risk patients with severe symptomatic aortic stenosis. More than 80 000 TAVR procedures have been performed in the United States and the number is growing every year. Two valve designs are approved in the United States including the balloon expandable Edwards Sapien prosthesis and self-expanding CoreValve prosthesis. The PARTNER trial of the Sapien valve, involving patients who were considered inoperable, reported a 19% absolute risk reduction in mortality compared with medical therapy, with a number needed to treat of 5...
December 14, 2017: Journal of Cardiopulmonary Rehabilitation and Prevention
https://www.readbyqxmd.com/read/29247516/impact-of-coronary-artery-disease-in-patients-undergoing-transcatheter-aortic-valve-replacement-insights-from-the-france-2-registry
#13
Etienne Puymirat, Romain Didier, Hélène Eltchaninoff, Bernard Lung, Jean-Philippe Collet, Dominique Himbert, Eric Durand, Alain Leguerrier, Pascal Leprince, Jean Fajadet, Emmanuel Teiger, Karine Chevreul, Michel Lièvre, Didier Tchetché, Florence Leclercq, Stéphan Chassaing, Hervé Le Breton, Patrick Donzeau-Gouge, Thierry Lefèvre, Didier Carrié, Martine Gillard, Didier Blanchard
BACKGROUND: Coronary artery disease (CAD) is common in patients undergoing transcatheter aortic valve replacement (TAVR). However, the impact of CAD distribution before TAVR on short- and long-term prognosis remains unclear. HYPOTHESIS: We hypothesized that the long-term clinical impact differs according to CAD distribution in patients undergoing TAVR using the FRench Aortic National CoreValve and Edwards (FRANCE-2) registry. METHODS: FRANCE-2 is a national French registry including all consecutive TAVR performed between 2010 and 2012 in 34 centers...
December 16, 2017: Clinical Cardiology
https://www.readbyqxmd.com/read/29223434/durability-of-quality-of-life-benefits-of-transcatheter-aortic-valve-replacement-long-term-results-from-the-corevalve-us-extreme-risk-trial
#14
MULTICENTER STUDY
Suzanne J Baron, Suzanne V Arnold, Matthew R Reynolds, Kaijun Wang, Michael Deeb, Michael J Reardon, James Hermiller, Steven J Yakubov, David H Adams, Jeffrey J Popma, David J Cohen
BACKGROUND: For patients with severe aortic stenosis (AS) at extreme surgical risk, transcatheter aortic valve replacement (TAVR) leads to improved survival and health status when compared with medical therapy. Whether the early health status benefits of TAVR in these patients are sustained beyond 1 year of follow-up is unknown. METHODS AND RESULTS: Six hundred thirty-nine patients with severe AS at extreme surgical risk underwent TAVR in the CoreValve US Extreme Risk Pivotal trial...
December 2017: American Heart Journal
https://www.readbyqxmd.com/read/29195573/complications-after-self-expanding-transcatheter-or-surgical-aortic-valve-replacement
#15
RANDOMIZED CONTROLLED TRIAL
John V Conte, James Hermiller, Jon R Resar, G Michael Deeb, Thomas G Gleason, David H Adams, Jeffrey J Popma, Steven J Yakubov, Daniel Watson, Jia Guo, George L Zorn, Michael J Reardon
Procedural complications following transcatheter aortic valve replacement (TAVR) or surgical aortic valve replacement (SAVR) are usually reported as retrospective analyses. We report the first comparison of complications following SAVR or self-expanding TAVR from a prospectively randomized study of high-risk SAVR patients. Three hundred ninety-five TAVR and 402 SAVR patients were prospectively enrolled and randomized 1:1 to TAVR with a CoreValve bioprosthesis or a surgical bioprosthetic valve. The rates of major procedural and vascular complications occurring (periprocedurally (0-3 days) and early (4-30 days)) were compared for TAVR vs SAVR patients...
2017: Seminars in Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/29185614/permanent-pacing-after-transcatheter-aortic-valve-implantation-incidence-predictors-and-evolution-of-left-ventricular-function
#16
Cláudio Monteiro, Andres Di Leoni Ferrari, Paulo Ricardo Avancini Caramori, Luiz Antonio Ferreira Carvalho, Dimytri Alexandre de Alvim Siqueira, Luiz Eduardo Koenig São Thiago, Marco Perin, Valter C de Lima, Enio Guérios, Fabio Sandoli De Brito
BACKGROUND: Transcatheter aortic valve implantation (TAVI) is a well-established procedure; however, atrioventricular block requiring permanent pacemaker implantation (PPI) is a common complication. OBJECTIVES: To determine the incidence, predictors and clinical outcomes of PPI after TAVI, focusing on how PPI affects left ventricular ejection fraction (LVEF) after TAVI. METHODS: The Brazilian Multicenter TAVI Registry included 819 patients submitted to TAVI due to severe aortic stenosis from 22 centers from January/2008 to January/2015...
November 27, 2017: Arquivos Brasileiros de Cardiologia
https://www.readbyqxmd.com/read/29174390/direct-aortic-access-for-transcatheter-aortic-valve-replacement-using-a-self-expanding-device
#17
Daniel P O'Hair, Tanvir K Bajwa, Jeffrey J Popma, Daniel R Watson, Steven J Yakubov, David H Adams, Samin Sharma, Newell Robinson, George Petrossian, Michael Caskey, Timothy Byrne, Neal S Kleiman, Angie Zhang, Michael J Reardon
BACKGROUND: Transcatheter aortic valve replacement (TAVR) using a self-expanding valve has been shown to be superior to an open operation in high-risk patients. Extensive iliofemoral peripheral vascular disease can prohibit femoral access. In these cases, direct aortic (DA) implantation may be a suitable option. METHODS: The current analysis compared outcomes in patients undergoing TAVR with the self-expanding CoreValve prosthesis (Medtronic, Minneapolis, MN) by direct aortic (DA) access vs iliofemoral (IF) access...
November 21, 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29146552/cardiogenic-shock-complicating-transcatheter-aortic-valve-replacement-due-to-severe-para-valvular-regurgitation
#18
M Chadi Alraies, Mohamad Soud, Homam Moussa Pacha, Ron Waksman, Itsik Ben-Dor
We describe a challenging case of successful use of Impella CP™ to provide emergent left ventricular support following a circulatory collapse during transcatheter valve-in-valve implantation with a CoreValve Evolut R prosthesis.
November 5, 2017: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/29130587/pushing-boundaries-implantation-of-the-34-mm-medtronic-corevalve-in-patients-with-a-large-aortic-annulus
#19
Adham Elmously, Berhane Worku, S Chiu Wong, Arash Salemi
The relationship between adherence to the recommended CoreValve sizing parameters and clinical outcomes is not well known for the recently released 34 mm valve, which is currently the largest available transcatheter valve. There is a presumed temporal reduction in paravalvular regurgitation in patients who receive an in-range valve, however, certain patients possess annular dimensions that are too large. We therefore describe two patients with annular dimensions larger than the manufacturer recommended range for the 34 mm CoreValve, who despite this underwent transcatheter aortic valve replacement with excellent clinical outcomes...
November 11, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/29118326/incidence-predictors-and-outcome-of-prosthesis-patient-mismatch-after-transcatheter-aortic-valve-replacement-a-systematic-review-and-meta-analysis
#20
Yan-Biao Liao, Yi-Jian Li, Li Jun-Li, Zhen-Gang Zhao, Xin Wei, Jiay-Yu Tsauo, Tian-Yuan Xiong, Yuan-Ning Xu, Yuan Feng, Mao Chen
The aim of this study was to investigate the incidence, predictors and outcome of prosthesis-patient mismatch (PPM) following transcatheter aortic valve replacement (TAVR). A total of 30 articles incorporating 4,691 patients were identified. The pooled incidences of overall, moderate and severe PPM following TAVR were 33.0%, 25.0% and 11.0% respectively. Medtronic CoreValve (MCV) had lower incidence of overall (32% vs: 40%, P < 0.0001) and moderate (23% vs 32%, P < 0.0001) than Edwards Sapien (ESV)...
November 8, 2017: Scientific Reports
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