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https://www.readbyqxmd.com/read/28538451/similar-anatomical-reduction-and-lower-complication-rates-with-the-sinus-tarsi-approach-compared-with-the-extended-lateral-approach-in-displaced-intra-articular-calcaneal-fractures
#1
Tim Schepers, Manouk Backes, Siem A Dingemans, Vincent M de Jong, Jan S K Luitse
OBJECTIVES: To investigate whether the sinus tarsi approach (STA) allows for a similar anatomical reduction of the posterior talocalcaneal facet as the extended lateral approach (ELA) and compare the rate of postoperative wound complications. DESIGN: Retrospective. SETTING: Level 1 trauma center. PATIENTS: All consecutive patients from 2012 to 2015 with a closed displaced intra-articular calcaneal fracture Sanders type II and III surgically treated with the ELA (N = 60) and the STA (N = 65)...
June 2017: Journal of Orthopaedic Trauma
https://www.readbyqxmd.com/read/28528026/implantation-of-a-durable-left-ventricular-assist-device-how-i-teach-it
#2
EDITORIAL
John M Stulak, Ashraf Abou El Ela, Francis D Pagani
No abstract text is available yet for this article.
June 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/28511565/the-role-of-membrane-transporters-in-ovarian-cancer-chemoresistance-and-prognosis
#3
Ela Cerovska, Katerina Elsnerova, Radka Vaclavikova, Pavel Soucek
Ovarian cancer has the highest mortality rate of all cancers in women. There is currently no effective method for early diagnosis, limiting the precision of clinical expectations. Predictions of therapeutic efficacy are currently not available either. Specifically, the development of chemoresistance against conventional chemotherapy poses a fundamental complication. Some membrane transporters have been reported to influence chemoresistance, which is often associated with a poor prognosis. Areas covered: The aim of this article is to review the existing information about membrane transporters and their role in both ovarian cancer chemoresistance and its outcomes...
May 16, 2017: Expert Opinion on Drug Metabolism & Toxicology
https://www.readbyqxmd.com/read/28499915/early-life-stress-and-later-peer-distress-on-depressive-behavior-in-adolescent-female-rats-effects-of-a-novel-intervention-on-gaba-and-d2-receptors
#4
Jodi L Lukkes, Shirisha Meda, Britta S Thompson, Nadja Freund, Susan L Andersen
Early life adversity (ELA) increases the risk of depression during adolescence that may result from a decline in parvalbumin (PVB) secondary to increased neuroinflammation. In this study, we investigated depressive-like behavior following exposure to two different types of stressors that are relevant for their developmental period: 1) chronic ELA (maternal separation; MS) and 2) an acute emotional stressor during adolescence (witnessing their peers receive multiple shocks; WIT), and their interaction. We also determined whether reducing inflammation by cyclooxygenase-2 (COX-2) inhibition would prevent the onset of depressive-like behavior...
May 9, 2017: Behavioural Brain Research
https://www.readbyqxmd.com/read/28498633/how-does-radioactive-iodine-affect-the-nose
#5
Ela Araz Server, Tolga Kirgezen, Ozlem Onerci Celebi, Muhammet Yildiz, Ozgur Yigit, Tevfik Fikret Cermik
OBJECTIVES/HYPOTHESIS: To determine the effect of radioactive iodine (RAI) treatment on the nasal mucosa and nasal functions. STUDY DESIGN: Prospective clinical study. METHODS: This study included 41 patients (31 female and 10 male) who were treated with RAI for papillary thyroid carcinoma. A visual analogue scale (VAS) was used for subjective evaluation of nasal symptoms. The saccharine test, nasal Schirmer test, and acoustic rhinometry were used for objective evaluation of nasal functions...
May 12, 2017: Laryngoscope
https://www.readbyqxmd.com/read/28494102/non-invasive-carotid-artery-elastography-using-multi-element-synthetic-aperture-imaging-phantom-and-in-vivo-evaluation
#6
Rohit Nayak, Giovanni Schifitto, Marvin M Doyley
PURPOSE: Vascular elastography can visualize the strain distribution in the carotid artery, which could be useful in assessing the propensity of advanced plaques to rupture. In our previous studies, we demonstrated that sparse synthetic aperture (SA) imaging can produce high quality vascular strain elastograms. However, the low output power of SA imaging may hamper its clinical utility. In this study, we hypothesize that multi-element defocused emissions can overcome this limitation and improve the quality of the vascular strain elastograms...
May 11, 2017: Medical Physics
https://www.readbyqxmd.com/read/28489166/anatomic-variations-of-hepatic-artery-a-study-in-479-liver-transplantations
#7
Olival Cirilo Lucena da Fonseca-Neto, Heloise Caroline de Souza Lima, Priscylla Rabelo, Paulo Sérgio Vieira de Melo, Américo Gusmão Amorim, Cláudio Moura Lacerda
Background: The incidence of anatomic variations of hepatic artery ranges from 20-50% in different series. Variations are especially important in the context of liver orthotopic transplantation, since, besides being an ideal opportunity for surgical anatomical study, their precise identification is crucial to the success of the procedure. Aim: To identify the anatomical variations in the hepatic arterial system in hepatic transplantation. Methods: 479 medical records of transplanted adult patients in the 13-year period were retrospectively analyzed, and collected data on hepatic arterial anatomy of the deceased donor...
January 2017: Arquivos Brasileiros de Cirurgia Digestiva: ABCD, Brazilian Archives of Digestive Surgery
https://www.readbyqxmd.com/read/28489165/detection-of-occult-lymph-node-tumor-cells-in-node-negative-gastric-cancer-patients
#8
Marina Alessandra Pereira, Marcus Fernando Kodama Pertille Ramos, Andre Roncon Dias, Osmar Kenji Yagi, Sheila Friedrich Faraj, Bruno Zilberstein, Ivan Cecconello, Evandro Sobroza de Mello, Ulysses Ribeiro-Jr
Background: The presence of lymph nodes metastasis is one of the most important prognostic indicators in gastric cancer. The micrometastases have been studied as prognostic factor in gastric cancer, which are related to decrease overall survival and increased risk of recurrence. However, their identification is limited by conventional methodology, since they can be overlooked after routine staining. Aim: To investigate the presence of occult tumor cells using cytokeratin (CK) AE1/AE3 immunostaining in gastric cancer patients histologically lymph node negative (pN0) by H&E...
January 2017: Arquivos Brasileiros de Cirurgia Digestiva: ABCD, Brazilian Archives of Digestive Surgery
https://www.readbyqxmd.com/read/28489158/prevalence-and-predictors-of-changes-in-bowel-habits-after-laparoscopic-cholecystectomy
#9
Leonardo de Mello Del Grande, Luis Fernando Paes Leme, Francisco Pimenta Marques, Andressa Teruya Ramos, Paula Teruya Ramos, Felipe Araújo de Souza
Background: The incidence of cholecystolithiasis is approximately 15% of the population. It is believed that between 30-40% of cholecystectomy patients have symptoms after surgery, being changes in bowel habits the most common among them. Aim: 1) Defining the prevalence, and 2) identifying predictors of changes in bowel habits after laparoscopic cholecystectomy. Methods: This is a retrospective cross-sectional study with an initial sample of 150 patients diagnosed with cholecystolithiasis operated between July and September 2014...
January 2017: Arquivos Brasileiros de Cirurgia Digestiva: ABCD, Brazilian Archives of Digestive Surgery
https://www.readbyqxmd.com/read/28486842/impact-of-angioscopic-evaluation-for-femoropopliteal-in-stent-restenosis-before-and-after-excimer-laser-atherectomy
#10
Akiko Idemoto, Naotaka Okamoto, Akihiro Tanaka, Naoki Mori, Daisuke Nakamura, Masamichi Yano, Nobuhiko Makino, Yasuyuki Egami, Ryu Shutta, Jun Tanouchi, Masami Nishino
In-stent restenosis (ISR) is a prevalent problem following stenting of femoropopliteal lesions. A potential novel treatment modality for ISR including excimer laser atherectomy (ELA) has become available. We performed ELA for in-stent chronic total occlusion (CTO) of femoropopliteal lesions and evaluated lesion morphology before and after ELA by angioscopy in 2 patients. The angioscopic findings clearly showed removal of in-stent thrombi after ELA. Thus, ELA may be effective for in-stent CTO of femoropopliteal lesions...
January 1, 2017: Vascular and Endovascular Surgery
https://www.readbyqxmd.com/read/28483808/setting-boundaries-public-views-on-limiting-patient-and-physician-autonomy-in-health-care-decisions
#11
Maureen Maurer, Rikki Mangrum, Kristin L Carman, Marjorie Ginsburg, Marthe R Gold, Shoshanna Sofaer, Ela Pathak-Sen, Jennifer Richmond, Joanna Siegel
We obtained and qualitatively analyzed input from more than nine hundred citizens during seventy-six public deliberation sessions about patient and physician autonomy in decision making, setting health care boundaries, and the tensions among competing social values. Generally, participants resisted interference with the patient-physician relationship and believed strongly in the freedom of patient and physician to control individual medical decisions. However, during deliberation participants identified two situations where boundaries and regulations in health care were more acceptable: protecting people from harm and allocating limited resources...
May 8, 2017: Journal of Health Politics, Policy and Law
https://www.readbyqxmd.com/read/28472846/-the-prognostic-validity-of-the-functional-capacity-evaluation-ela-in-work-related-medical-rehabilitation
#12
David Bühne, Torsten Alles, Christian Hetzel, Ingo Froböse
The aim of the study was to determine the ability of FCE (Functional Capacity Evaluation) to predict sustained return-to-work (RTW). A multicentric prospective cohort study was conducted in cooperation with 4 outpatient rehabilitation clinics. The sample consisted of 198 patients. Sustained RTW was defined as a combination of employment at 3-month follow-up with a low level of sick leave (dependent variable 1) resp. with a moderate or better rating of the current work ability with respect to the physical demands at work (dependent variable 2)...
May 4, 2017: Die Rehabilitation
https://www.readbyqxmd.com/read/28470098/chicken-embryo-lethality-assay-for-determining-the-lethal-dose-and-virulence-of-enterococcus-faecalis
#13
Ana E Blanco, Martin Barz, Wiebke Icken, David Cavero, Reza Sharifi, Matthias Voss, Rudolf Preisinger, Carlos Buxadé
Enterococcus faecalis is the major pathogen found in field cases of amyloid arthropathy in chickens. Given the need of a better understanding of the virulence mechanisms of the causative strains, the Embryo Lethality Assay (ELA) is proposed in the present study as a model to evaluate the virulence of E. faecalis strains, specifically the pathogenic avian strain K923/96, which was previously related with amyloid arthropathy. Hence, 0.2 ml of five doses of the cited strain (from 2.5 to 2500 colony-forming unit (CFU) per ml) were inoculated into the allantoic cavity of 10 day-old embryos...
May 4, 2017: Avian Pathology: Journal of the W.V.P.A
https://www.readbyqxmd.com/read/28466434/non-heterosexuality-relationships-and-young-women-s-contraceptive-behavior
#14
Elizabeth J Ela, Jamie Budnick
Non-heterosexual young women have a higher rate of unintended pregnancy than their heterosexual peers, but their fertility behaviors are understudied. We use longitudinal data from the Relationship Dynamics and Social Life study to investigate mechanisms contributing to non-heterosexual women's higher pregnancy risk. These data include weekly reports of relationships, sex, and contraceptive use over 30 months. We compare the relationships and fertility behaviors of three groups: exclusively heterosexual (consistent heterosexual behavior, identity, and attraction); mostly heterosexual (heterosexual identity with same-sex behavior and/or same-sex attraction); and LGBTQ (any non-heterosexual identity)...
May 2, 2017: Demography
https://www.readbyqxmd.com/read/28466019/plant-proteinase-inhibitor-bbci-modulates-lung-inflammatory-responses-and-mechanic-and-remodeling-alterations-induced-by-elastase-in-mice
#15
Rafael Almeida-Reis, Osmar A Theodoro-Junior, Bruno T M Oliveira, Leandro V Oliva, Alessandra C Toledo-Arruda, Camila R Bonturi, Marlon V Brito, Fernanda D T Q S Lopes, Carla M Prado, Ariana C Florencio, Mílton A Martins, Caroline A Owen, Edna A Leick, Maria L V Oliva, Iolanda F L C Tibério
Background. Proteinases play a key role in emphysema. Bauhinia bauhinioides cruzipain inhibitor (BbCI) is a serine-cysteine proteinase inhibitor. We evaluated BbCI treatment in elastase-induced pulmonary alterations. Methods.  C57BL/6 mice received intratracheal elastase (ELA group) or saline (SAL group). One group of mice was treated with BbCI (days 1, 15, and 21 after elastase instillation, ELABC group). Controls received saline and BbCI (SALBC group). After 28 days, we evaluated respiratory mechanics, exhaled nitric oxide, and bronchoalveolar lavage fluid...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28452825/joint-impact-of-early-life-adversity-and-comt-val158met-rs4680-genotypes-on-the-adult-cortisol-response-to-psychological-stress
#16
William R Lovallo, Mary-Anne Enoch, Kristen H Sorocco, Andrea S Vincent, Ashley Acheson, Andrew J Cohoon, Colin A Hodgkinson, David Goldman
OBJECTIVE: Exposure to stress during critical periods of development can diminish stress reactivity by the hypothalamic-pituitary-adrenocortical axis. Genetic characteristics may further modify this effect of early adversity, leading to a gene-by-environment (G x E) interaction on stress reactivity in adulthood. Val-allele carriers of a common polymorphism of the COMT gene (Val158Met, rs4680) have rapid removal of catecholamines in the prefrontal cortex, limbic system, and reward centers...
April 27, 2017: Psychosomatic Medicine
https://www.readbyqxmd.com/read/28452125/stepwise-application-of-fib-4-red-cell-distribution-width-platelet-ratio-and-apri-for-compensated-hepatitis-b-fibrosis-detection
#17
Yong-Peng Chen, Xiao-Min Hu, Xie-Er Liang, Li-Wen Huang, You-Fu Zhu, Jin-Lin Hou
AIM: FIB-4 and APRI were validated with unsatisfactory efficiency. Routine hematology in-dex red cell distribution width-platelet ratio (RPR) had been tried in Liver Fibrosis detection. This study tries to evaluate the stepwise application of FIB-4, RPR and APRI in detecting CHB fibrosis. METHODS: A total of 246 compensated CHB patients underwent liver biopsies, transient elas-tography and routine blood tests including complete blood count were included. Dual Cutoffs were determined to exclude or include cirrhosis diagnosis...
April 28, 2017: Journal of Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28451551/an-ethical-review-of-euthanasia-and-physician-assisted-suicide
#18
Božidar Banović, Veljko Turanjanin, Anđela Miloradović
BACKGROUND: In the majority of countries, active direct euthanasia is a forbidden way of the deprivation of the patients' life, while its passive form is commonly accepted. This distinction between active and passive euthanasia has no justification, viewed through the prism of morality and ethics. Therefore, we focused on attention on the moral and ethical implications of the aforementioned medical procedures. METHODS: Data were obtained from the Clinical Hospital Center in Kragujevac, collected during the first half of the 2015...
February 2017: Iranian Journal of Public Health
https://www.readbyqxmd.com/read/28439197/clinical-and-polysomnographic-features-of-children-evaluated-with-polysomnography-in-pediatric-sleep-laboratory
#19
Hatice Ezgi Barış, Yasemin Gökdemir, Ela Erdem Eralp, Nilay Baş İkizoğlu, Fazilet Karakoç, Bülent Karadağ, Refika Ersu
AIM: Sleep disordered breathing is a common problem in childhood that encompasses a spectrum of disorders extending from primary snoring to obstructive sleep apnea. This study aims to investigate the results of children undergoing evaluation with polysomnography in the sleep laboratory of a tertiary care hospital. MATERIAL AND METHODS: Demographic and clinical features as well as sleep associated symptoms, scores of pediatric sleep questionnaire and Pittsburgh sleep quality index and polysomnography results are retrospectively evaluated...
March 2017: Türk Pediatri Arşivi
https://www.readbyqxmd.com/read/28439003/numerical-evidence-for-thermally-induced-monopoles
#20
Peter Wirnsberger, Domagoj Fijan, Roger A Lightwood, Anđela Šarić, Christoph Dellago, Daan Frenkel
Electric charges are conserved. The same would be expected to hold for magnetic charges, yet magnetic monopoles have never been observed. It is therefore surprising that the laws of nonequilibrium thermodynamics, combined with Maxwell's equations, suggest that colloidal particles heated or cooled in certain polar or paramagnetic solvents may behave as if they carry an electric/magnetic charge. Here, we present numerical simulations that show that the field distribution around a pair of such heated/cooled colloidal particles agrees quantitatively with the theoretical predictions for a pair of oppositely charged electric or magnetic monopoles...
May 9, 2017: Proceedings of the National Academy of Sciences of the United States of America
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