keyword
https://read.qxmd.com/read/38267106/efficacy-and-safety-of-mtor-inhibition-in-cutaneous-sarcoidosis-a-single-centre-trial
#21
RANDOMIZED CONTROLLED TRIAL
Anna Redl, Konstantin Doberer, Luisa Unterluggauer, Lisa Kleissl, Christoph Krall, Carolina Mayerhofer, Bärbel Reininger, Victoria Stary, Nina Zila, Wolfgang Weninger, Thomas Weichhart, Christoph Bock, Thomas Krausgruber, Georg Stary
BACKGROUND: Sarcoidosis is an inflammatory condition that can affect various organs and tissues, causing the formation of granulomas and subsequent functional impairment. The origin of sarcoidosis remains unknown and there are few treatment options. Mechanistic target of rapamycin (mTOR) activation is commonly seen in granulomas of patients across different tissues and has been shown to induce sarcoidosis-like granulomas in a mouse model. This study aimed to examine the efficacy and safety of the mTOR inhibitor sirolimus as a treatment for cutaneous sarcoidosis...
February 2024: Lancet Rheumatology
https://read.qxmd.com/read/38256637/cutaneous-adverse-reactions-associated-with-tattoos-and-permanent-makeup-pigments
#22
REVIEW
Beatrice Bălăceanu-Gurău, Eliza Apostol, Mădălina Caraivan, Ana Ion, Raluca Tatar, Mara Mădălina Mihai, Liliana Gabriela Popa, Cristian-Dorin Gurău, Olguța Anca Orzan
Tattooing is the procedure of implanting permanent pigment granules and additives into the dermal layer of the skin, serving various purposes such as decoration, medical identification, or accidental markings. There has been a significant rise in the popularity of decorative tattooing as a form of body art among both teenagers and young adults. Thus, the incidence of tattoos is increasing, with expanding applications such as permanent makeup, scar camouflage, nipple-areola, lips, and eyebrows tattooing, and utilization in oncological radiotherapy such as colon marking...
January 16, 2024: Journal of Clinical Medicine
https://read.qxmd.com/read/38256455/tattoo-associated-skin-reaction-in-a-melanoma-patient-receiving-b-raf-and-mek-inhibitors-a-case-report-with-an-emphasis-on-etiopathogenic-and-histological-features
#23
Silvia Baratta, Gerardo Cazzato, Caterina Foti, Giuseppe Ingravallo, Lucia Lospalluti, Carmelo Laface, Raffaele Filotico, Francesca Ambrogio
Tattoo-associated cutaneous reactions have become quite frequent given the increasing percentage of tattooed subjects globally and also in Italy. On the other hand, the increasing use of target therapy is showing the ability of these drugs to affect the immune system and also cause adverse tattoo-related reactions. In this paper, we report a case of a 42-year-old patient with stage-IIID melanoma undergoing treatment with Dabrafenib and Trametinib. The patient reported erythema, oedema and scaling in areas of the body containing a black tattoo, and, conversely, no signs and/or symptoms in areas with tattoos of a different color...
January 6, 2024: Journal of Clinical Medicine
https://read.qxmd.com/read/38186199/early-presentation-of-allergic-contact-dermatitis-due-to-paraphenylenediamine
#24
Irene Andrés Alberola, Eva Jiménez Hernández, José F Soltero Carracedo, Alba Macías Panedas, Natalia Martín Iranzo, María Bartolomé Morate, Susana Alberola López, Jesús Rodríguez Calleja
Allergic contact dermatitis (ACD) is a more frequent pathology in adults than in children, because, in most cases, allergic sensitization requires a prolonged exposure time to the allergen, mostly months or years. In fact, the actual incidence and prevalence of ACD in children and adolescents is unknown. However, there is a hypothesis that ACD is increasing in the pediatric population. Among the allergens involved in ACD, the frequency of paraphenylenediamine (PPDA) is increasing. PPDA is one of the five most common contact allergens in the general population and one of the 10 most common contact allergens in children...
2024: Allergologia et Immunopathologia
https://read.qxmd.com/read/38162536/nipple-areola-complex-prosthesis-as-a-new-arsenal-for-breast-reconstruction
#25
JOURNAL ARTICLE
Ali Modarressi, Louisa Empen, Charlotte Favre
Nipple and areola complex (NAC) recreating is primordial to achieve a complete breast reconstruction. Some patients would not benefit or choose to undergo surgical or tattoo NAC reconstruction. Recently, innovative NAC silicone prostheses have been developed that are applied over the skin and come in various shapes, sizes, and colors to match different NAC tones and sizes. Our prospective study aims to evaluate for the first time, to our knowledge, the safety of these prostheses and patients' and surgeons' satisfaction using a 30-day survey...
March 2024: JPRAS Open
https://read.qxmd.com/read/38129584/biotagging-method-for-animal-identification-using-dissolvable-microneedle-arrays-prepared-by-customisable-moulds
#26
JOURNAL ARTICLE
Jongho Park, Beomjoon Kim
Properly handling animals and understanding their habits are crucial to establish a society where humans and animals coexist. Thus, identifying individual animals, including their possessions, and adequately managing each animal is necessary. Although several conventional identification methods exist, such as the use of ear punch, tattoos, and radio frequency (RF) chips, they require several processes and external apparatus. In this study, we proposed a new biotagging method using a microneedle array for animal identification...
December 21, 2023: Scientific Reports
https://read.qxmd.com/read/38110831/picosecond-lasers-in-cosmetic-dermatology-where-are-we-now-an-overview-of-types-and-indications
#27
REVIEW
Diala Haykal, Hugues Cartier, Cyril Maire, Serge Mordon
Q-switched lasers have undeniably revolutionized the field of laser dermatology since four decades ago. Just as the first-generation laser emits its photonic signal in a few nanoseconds, the picosecond laser delivers pulse widths of at least ten times shorter. These devices offer a powerful tool for treating a wide range of skin conditions with a minimal downtime for visible improvement. For the current study, a literature research was performed on the dermatological applications of picosecond laser. The literature searched on this topic between 1999 and 2023 accessible through various platforms produce a result of 62 articles...
December 18, 2023: Lasers in Medical Science
https://read.qxmd.com/read/38106780/identifying-human-trafficking-victims-a-potential-role-for-forensic-dermatology
#28
EDITORIAL
Philip R Cohen
Human trafficking is a worldwide problem that predominantly affects women and children. The victims are recruited by coercion, deception, or force and then exploited for commercial sex acts or labor, or both. Human trafficking results in severe suffering of the victims including not only physical injuries but also psychological consequences. Many of the victims of human trafficking encounter the medical system; however, this chance for potential intervention is often not realized by the clinician treating the individual...
November 2023: Curēus
https://read.qxmd.com/read/38104547/the-process-of-sterilizing-tattoo-inks-releases-formaldehyde
#29
JOURNAL ARTICLE
Seung Hee Lee, Myoungjin Kim, Seongnam Kim, Hong Bae Kim
INTRODUCTION: Around 12% of Europeans and 20% of Americans have at least one tattoo. Tattoo inks, the substances used to create tattoos on the body, consist of chemicals that contain formaldehyde, which can be harmful to human health. The amount of formaldehyde present in commercially available Tattoo inks and its causes are not well-understood. METHODS: We investigated the levels of formaldehyde in tattoo ink products sold in different countries and identified the factors contributing to its production...
December 16, 2023: Dermatology: International Journal for Clinical and Investigative Dermatology
https://read.qxmd.com/read/38082921/a-preliminary-usability-study-of-integrated-electronic-tattoo-surface-electromyography-semg-sensors
#30
JOURNAL ARTICLE
Jihoon Lim, Mingrui Sun, Jefferson Zhe Liu, Ying Tan
Surface electromyography (sEMG) sensor measures the user's muscle activities by noninvasively placing electrodes on the surface of the user's skin. It has been widely used in monitoring various human movements. Recently a wearable and flexible epidermal sensor system called Electronic Tattoo (E-Tattoo) has been developed to enable intimate attachment of electrodes on the skin, improving long-term comfort. In order to make the E-Tattoo usable in monitoring muscle activities, it is always connected with a connector and signal processing blocks to collect and process the measured sEMG signals...
July 2023: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://read.qxmd.com/read/38081147/tattoo-associated-skin-reactions-a-danish-population-based-survey-in-5-914-tattooed-individuals
#31
JOURNAL ARTICLE
Karina Friis, Anne Marie Ladehoff Thomsen, Jørn Olsen, Mikael Rahbek Rørth, Jørgen Serup
Background In Europe, Australia and the US, the estimated overall prevalence of tattooing is around 10-20%. Tattoo ink often comprises harmful chemicals and epidemiological studies on adverse effects of tattoos are lacking. Objectives We aimed to estimate the prevalence of tattoo-associated skin reactions in the general Danish population and describe individuals with tattoo-associated skin reactions by socio-demographic factors and tattoo characteristics. Methods The study was based on respondents aged 16 years or older from a population-based 2021 survey entitled "How are you?" conducted in the Central Denmark Region (n = 33,925)...
December 11, 2023: Dermatology: International Journal for Clinical and Investigative Dermatology
https://read.qxmd.com/read/38076654/laser-removal-of-eyeliner-and-eyebrow-tattoos-chart-review-experiences-and-learnings
#32
JOURNAL ARTICLE
Elizabeth Kream, Neil Jairath, Shirin Bajaj, David Orbuch, Jordan V Wang, Roy G Geronemus
BACKGROUND: Cosmetic tattoos in the periocular area, including microblading, have become increasingly popular. More patients have been seeking laser tattoo removal. OBJECTIVE: A retrospective chart review for the laser treatment of eyeliner and eyebrow tattoos and a discussion of treatment experiences can better inform physicians. METHODS: A retrospective chart review was performed over five years with patients who had eyeliner and/or eyebrow tattoos and had laser removal...
November 2023: Journal of Clinical and Aesthetic Dermatology
https://read.qxmd.com/read/38071614/a-simple-drug-delivery-microneedling-technique-modality-successfully-improves-linear-atrophic-scars
#33
JOURNAL ARTICLE
Luciana Gasques de Souza, Michael H Gold, Denise Steiner, Marcio Roberto Silva, Gisele Viana de Oliveira
BACKGROUND: Atrophic scars are white, dermal depressions, caused by the destruction of collagen fibers and decrease in epidermal cells, following inflammation after different types of trauma. They lead to significant physical, aesthetic and psychological barriers and their treatment remain a therapeutic challenge for dermatologists. Microneedling has been shown to improve scars by stimulating angiogenesis and neocolagenesis and the combination of anti-fibrotic drugs could potentialize the results...
December 10, 2023: Journal of Cosmetic Dermatology
https://read.qxmd.com/read/38058233/mycobacterium-haemophilum-infection-in-immunocompetent-adults-a-literature-review-and-case-report
#34
REVIEW
Yuan Sun, Huiyan Li
BACKGROUND: Mycobacterium haemophilum has been increasingly found in severely immunocompromised patients but is scarcely reported in immunocompetent adults. METHODS: We systematically reviewed previous literature to identify studies on infection in immunocompetent adults. Articles reporting at least one case of M. haemophilum infection were included. We excluded articles involving patients who had immunosuppression-related diseases and routinely used glucocorticoids or immunosuppressants...
December 6, 2023: International Journal of Dermatology
https://read.qxmd.com/read/38048269/respecting-the-art-of-medicine-wide-local-excision-of-melanoma-within-a-tattoo-sleeve
#35
JOURNAL ARTICLE
Hafsa Zuberi, Cecil Jordan Staples, Chad D Housewright
No abstract text is available yet for this article.
November 28, 2023: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://read.qxmd.com/read/38038794/tattoo-inks-evaluation-of-cellular-responses-and-analysis-of-some-trace-metals
#36
JOURNAL ARTICLE
Sumru Sozer Karadagli, Gizem Kaftan, Islam Cansever, Guliz Armagan, Ozlem Sogut
After tattoo application, inks remain in the skin, mostly in the dermal layer, and manufacturers use inks that have not been adequately evaluated for safety in tattoo production. In this study, the metal contents (Cd, Hg, Pb, and Cr) of tattoo inks available in the Turkish market were determined and the relationship between cell viability and inflammatory response of the detected metal levels was investigated. Nine tattoo inks (3 colors) from 3 different brands abbreviated as E, I, and W were examined...
December 1, 2023: Biometals: An International Journal on the Role of Metal Ions in Biology, Biochemistry, and Medicine
https://read.qxmd.com/read/38018868/review-of-optical-methods-for-non-invasive-imaging-of-skin-fibroblasts-from-in-vitro-to-ex-vivo-and-in-vivo-visualization
#37
REVIEW
Viktor V Nikolaev, Yury V Kistenev, Marius Kröger, Hala Zuhayri, Maxim E Darvin
Fibroblasts are among the most common cell types in the stroma responsible for creating and maintaining the structural organization of the extracellular matrix (ECM) in the dermis, skin regeneration, and a range of immune responses. Until now, the processes of fibroblast adaptation and functioning in a varying environment have not been fully understood. Modern laser microscopes are capable of studying fibroblasts in vitro and ex vivo. One-photon- and two-photon-excited fluorescence microscopy, Raman spectroscopy/micro-spectroscopy are well-suited non-invasive optical methods for fibroblast imaging in vitro and ex vivo...
November 29, 2023: Journal of Biophotonics
https://read.qxmd.com/read/38018124/screen-printed-piezoelectric-sensors-on-tattoo-paper-combined-with-all-printed-high-performance-organic-electrochemical-transistors-for-electrophysiological-signal-monitoring
#38
REVIEW
Anatolii Makhinia, Valerio Beni, Peter Andersson Ersman
This work demonstrates sensitive and low-cost piezoelectric sensors on skin-friendly, ultrathin, and conformable substrates combined with organic electrochemical transistors (OECTs) for the detection and amplification of alternating low-voltage input signals. The fully screen-printed (SP) piezoelectric sensors were manufactured on commercially available tattoo paper substrates, while the all-printed OECTs, relying on an extended gate electrode architecture, were manufactured either by solely using SP or by combining SP and aerosol jet printing (AJP) on PET substrates...
November 28, 2023: ACS Applied Materials & Interfaces
https://read.qxmd.com/read/38013510/automated-classification-of-hidradenitis-suppurativa-disease-severity-by-convolutional-neural-network-analyses-using-calibrated-clinical-images
#39
JOURNAL ARTICLE
A Wiala, R Ranjan, H Schnidar, K Rappersberger, C Posch
BACKGROUND: The assessment of hidradenitis suppurativa (HS) severity requires detailed, and error-prone lesion counts. This proof-of-concept study aimed to automatically classify HS disease severity using machine learning of clinical smartphone images. METHODS: 777 ambient-light and size-controlled images were used to build a class-balanced synthetic dataset (n = 7675). Convolutional neural networks (CNN) were used for automated severity classification (scale 0-3), and to assess disease-dynamics...
November 27, 2023: Journal of the European Academy of Dermatology and Venereology: JEADV
https://read.qxmd.com/read/38006375/flat-warts-verrucae-planae-confined-to-the-pigment-of-a-tattoo-a-rare-tattoo-associated-complication
#40
JOURNAL ARTICLE
Nika Filipović, Davor Tomas, Marija Buljan
Tattoos are a form of decorative body art in which pigment dyes of different colors are inoculated into the skin. It is estimated that 15-25% of general population has one or more tattoos (1), and the reasons for the popularity of this procedure may include greater social acceptance, aesthetic appeal, or perhaps the option of using laser removal techniques to eliminate unwanted tattoos. Even though modern professional tattoos are usually performed in sterile conditions, complications still occur, and with increasing numbers of people getting tattoos, the incidence of tattoo-associated side-effects presenting to dermatologists, which may be as high as 2%, is likely to increase (2)...
November 2023: Acta Dermatovenerologica Croatica: ADC
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