Hong Zhang, Ruining Liu, Qingmei Li, Xiaolin Hu, Lixiang Wu, Ye Zhou, Guangchao Qing, Rui Yuan, Junjie Huang, Wei Gu, Yanyao Ye, Chao Qi, Mei Han, Xiaohui Chen, Xun Zhu, Yun Deng, Liangliang Zhang, Hengyi Chen, Haoran Zhang, Weiyin Gao, Yao Liu, Yang Luo
Accurate and rapid blood typing plays a vital role in a variety of biomedical and forensic scenarios, but recognizing weak agglutination remains challenging. Herein, we demonstrated a flipping identification with a prompt error-discrimination (FLIPPED) platform for automatic blood group readouts. Bromocresol green dye was exploited as a characteristic chromatography indicator for the differentiation of plasma from whole blood by presenting a teal color against a brown color. After integrating these color changes into a quick-response (QR) code, prompt typing of ABO and Rhesus groups was automatically achieved and data could be uploaded wirelessly within 30 s using a commercially available smartphone to facilitate blood cross-matching...
April 27, 2021: ACS Nano