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https://www.readbyqxmd.com/read/29028489/assessment-of-types-of-synthetic-cannabinoids-in-narcotic-cases-assessed-by-the-council-of-forensic-medicine-between-2011-2015-ankara-turkey
#1
Ersin Göl, İsmet Çok
Synthetic cannabinoids mimic the effects of cannabis and are the largest and fastest growing class of newly appearing designer drugs. Reports have revealed that various types of synthetic cannabinoids are mixed with herbal substances. The present study investigated the herbal substance cases involving synthetic cannabinoids in Ankara and nearby cities in Turkey. Data were collected from the reports of synthetic cannabinoids that were analyzed between January 01, 2011 and December 31, 2015 in the Ankara Narcotic Department of the Council of Forensic Medicine at the request of the judicial authorities...
October 4, 2017: Forensic Science International
https://www.readbyqxmd.com/read/29020788/-complete-molar-pregancy-with-development-of-non-metastatic-persistent-trophoblastic-diseasea-case-report-reflection-of-rules-of-care-and-decision-making-processes-forensic-responsibility-and-the-position-of-doctor-in-the-general-gynecologic-and-obstetric-outpatient
#2
S Zeman, P Trávník, K Dvořáková, J Zemanová
OBJECTIVE: To define the forensic responsibility and the position of doctor in the general gynecologic and obstetric outpatient practice in care of the complete molar pregancy. DESIGN: Case report and review article. SETTING: General gynecologic and obstetric outpatient practice Velké Meziříčí; Sanatorium REPROMEDA, Centre of reproductive medicine and preimplantation genetics, Brno; Histopatology department of Hospital Jihlava. CASE REPORT: The changing clinical presentation of complete molar pregnancy with development of non-metastatic gestational trophoblastic disease: management...
2017: Ceská Gynekologie
https://www.readbyqxmd.com/read/29020743/development-and-validation-of-a-multi-locus-dna-metabarcoding-method-to-identify-endangered-species-in-complex-samples
#3
Alfred J Arulandhu, Martijn Staats, Rico Hagelaar, Marleen M Voorhuijzen, Theo W Prins, Ingrid Scholtens, Adalberto Costessi, Danny Duijsings, François Rechenmann, Frédéric B Gaspar, Maria Teresa Barreto Crespo, Arne Holst-Jensen, Matthew Birck, Malcolm Burns, Edward Haynes, Rupert Hochegger, Alexander Klingl, Lisa Lundberg, Chiara Natale, Hauke Niekamp, Elena Perri, Alessandra Barbante, Jean-Philippe Rosec, Ralf Seyfarth, Tereza Sovová, Christoff Van Moorleghem, Saskia van Ruth, Tamara Peelen, Esther Kok
DNA metabarcoding provides great potential for species identification in complex samples such as food supplements and traditional medicines. Such a method would aid Convention on International Trade in Endangered Species of Wild Fauna and Flora (CITES) enforcement officers to combat wildlife crime by preventing illegal trade of endangered plant and animal species. The objective of this research was to develop a multi-locus DNA metabarcoding method for forensic wildlife species identification and to evaluate the applicability and reproducibility of this approach across different laboratories...
October 1, 2017: GigaScience
https://www.readbyqxmd.com/read/28980558/-realization-of-the-modern-educational-concept-for-the-organization-of-the-teaching-and-learning-activities-at-the-department-of-forensic-medicine-of-i-m-sechenov-first-moscow-state-medical-university-ministry-of-health-of-the-russian-federation
#4
Yu I Pigolkin, Yu V Lomakin, E N Leonova
The modern educational concept for the organization of the teaching and learning activities (continuous, free, and open education) implies the necessity for its implementation the development and introduction of the new approaches to the work with the students. This problem should be addressed based on the use of the up-to-date technologies for education of the adult subjects. Such technologies find the increasingly wider application at the Department of Forensic Medicine of the I.M. Sechenov First Moscow State Medical University...
2017: Sudebno-meditsinskaia Ekspertiza
https://www.readbyqxmd.com/read/28980535/the-nail-as-an-investigative-tool-in-medicine-what-a-dermatologist-ought-to-know
#5
REVIEW
Chander Grover, Shikha Bansal
The nail is an important skin appendage, but not many dermatologists are aware of the importance it receives outside our specialty. This article focuses on the nail in non-dermatological contexts. The nail is a keratinized matrix capable of continuous growth with the ability to incorporate various compounds within its structure. Therefore it can be used to monitor long-term consumption of drugs. It is also an excellent source of germ-line DNA for genetic analyses. With an increased undrstanding of nail physiology, there is now a better understanding of its connection to various pathologies as well...
October 4, 2017: Indian Journal of Dermatology, Venereology and Leprology
https://www.readbyqxmd.com/read/28977558/is-hair-analysis-useful-in-postmortem-cases
#6
Gudrun Høiseth, Marianne Arnestad, Ritva Karinen, Luca Morini, Sidsel Rogde, Cristina Sempio, Vigdis Vindenes, Åse Marit Leere Øiestad
In postmortem cases, detection of drugs in blood is most relevant with regard to determining cause of death. However, it is sometimes also of interest to gain as much information as possible regarding the deceased's use of drugs in the period before death. The aim of this study was to compare results from analyses of a repertoire of psychoactive medicinal drugs in blood and hair samples from a larger material of postmortem cases. Hair samples in addition to blood were collected from 55 forensic autopsies and analyzed for a repertoire of 39 medicinal drugs (benzodiazepines, antidepressants and antipsychotics) using av fully validated liquid chromatography-tandem mass spectrometry method...
September 14, 2017: Journal of Analytical Toxicology
https://www.readbyqxmd.com/read/28977427/chiral-resolution-and-enantioselectivity-of-synthetic-cathinones-a-brief-review
#7
Bárbara Silva, Carla Fernandes, Paula Guedes de Pinho, Fernando Remião
Chiral discrimination has become one of the most important fields in analytical and medicinal chemistry, and forensic toxicology. The enantiomers may have different binding to proteins that may lead to many pharmacological and toxicological differences between them, including kinetic (at the absorption, distribution, metabolism and excretion level) or dynamic (level of potency and efficacy or even differences in mechanism of action) variations. Cathinone derivatives are chiral compounds, sold via the internet for recreational use, and little is known about their enantiomeric selectivity...
September 6, 2017: Journal of Analytical Toxicology
https://www.readbyqxmd.com/read/28977413/identification-of-the-synthetic-cannabinoid-1-4-cyanobutyl-n-2-phenylpropan-2-yl-1h-indazole-3-carboxamide-cumyl-4cn-binaca-in-plant-material-and-quantification-in-post-mortem-blood-samples
#8
Oya Yeter
In May 2016, a new type of synthetic indazole-3-carboxamide cannabinoid (CUMYL-4CN-BINACA) was detected in seized plant material submitted to the Istanbul Council of Forensic Medicine by the National Police Office. The major ingredient in this material was purified using preparative liquid chromatography, and its structure was identified using liquid chromatography-high-resolution mass spectrometry (LC-HR/MS), gas chromatography-electron ionization/mass spectrometry (GC-EI/MS), nuclear magnetic resonance (NMR) spectroscopy and Fourier transform-infrared spectroscopy (FT-IR)...
August 31, 2017: Journal of Analytical Toxicology
https://www.readbyqxmd.com/read/28972355/-analysis-of-suicide-cases-in-post-mortem-examination-files-of-the-department-of-forensic-medicine-at-the-medical-university-of-bia%C3%A5-ystok-2003-to-2015
#9
Maciej Janica, Michał Szeremeta, Anna Bondar, Karolina Lomperta, Petra Drobuliakova, Anna Niemcunowicz-Janica
Aim of the study: The study presents the analysis of suicides based on the material consisting of the results of medico-legal autopsies and case files of the Department of Forensic Medicine of the Medical University of Bialystok. Material and methods: The material consisted of 6752 protocols of medico-legal autopsies carried out in the years 2003-2015 and case files, which enabled to classify cases as suicidal. The analysis included the dynamics of suicides over the years, basic demographic characteristics of victims, the ways, the time and place of suicide, the state of sobriety, the frequency of injuries in different regions of the body...
2017: Archiwum Medycyny Sa̧dowej i Kryminologii
https://www.readbyqxmd.com/read/28963643/is-bone-analysis-with-%C3%AE-ct-useful-for-short-postmortem-interval-estimation
#10
Erwan Le Garff, Vadim Mesli, Elodie Marchand, Hélène Behal, Xavier Demondion, Anne Becart, Valery Hedouin
The evaluation of the postmortem interval (PMI) is an important consideration in forensic medicine. The time between death and the discovery thereof is extremely important, not only in terms of the legal process, but also for the course of the investigation. At the time of the discovery of human bones, the evaluation of the PMI is extremely difficult. To date, there is no really effective tool for this evaluation. The objective of our study is to characterize the architectural modifications of human bones using micro-tomography (μCT) in the postmortem period...
September 30, 2017: International Journal of Legal Medicine
https://www.readbyqxmd.com/read/28960873/emerging-diagnostic-and-therapeutic-potentials-of-human-hair-proteomics
#11
Henry A Adeola, Jennifer C Wyk, Afolake Arowolo, Reginald M Ngwanya, Khwezikazi Mkentane, Nonhlanhla P Khumalo
The use of non-invasive human substrates to interrogate pathophysiological conditions has become essential in the post- Human Genome Project (HGP) era. Due to its high turnover rate, and its long term capability to incorporate exogenous and endogenous substances from the circulation; hair testing is emerging a key player in monitoring long term drug compliance, chronic alcohol abuse, forensic toxicology, and biomarker discovery, among other things. Novel high throughput 'omics based approaches like proteomics have been underutilized globally in comprehending human hair morphology and its evolving use as a diagnostic testing substrate in the era of precision medicine...
September 27, 2017: Proteomics. Clinical Applications
https://www.readbyqxmd.com/read/28954154/interpersonal-violence-circumstances-of-aggressions-and-patterns-of-maxillofacial-injuries-in-the-metropolitan-area-of-campina-grande-state-of-para%C3%A3-ba-brazil-2008-2011
#12
Ítalo Macedo Bernardino, Kevan Guilherme Nóbrega Barbosa, Lorena Marques Nóbrega, Gigliana Maria Sobral Cavalcante, Efigenia Ferreira E Ferreira, Sérgio d'Ávila
The aim of this study was to determine the circumstances of aggressions and patterns of maxillofacial injuries among victims of interpersonal violence. This was a cross-sectional and exploratory study conducted from the analysis of 7,132 medical-legal and social records of interpersonal violence victims seen in a Forensic Medicine and Dentistry Center. Descriptive and multivariate statistics were performed using Multiple Correspondence Analysis. Three groups with different victimization profiles were identified...
September 2017: Ciência & Saúde Coletiva
https://www.readbyqxmd.com/read/28950809/quality-of-life-in-dementia-sufferers-diet-and-exercise-in-an-evaluatory-role
#13
Pasquale Ricci, Francesco Massoni, Lidia Ricci, Emanuela Onofri, Giuseppe Donato, Serafino Ricci
Among the myriad of factors modulating quality of life (QoL) assessments estimated in patients presenting a variety of cognitive impairments (People With Dementia - PWD), the distinctive and critical influence of diet and exercise cannot be overestimated. The present study reviews the evi-dence to confirm the association between these health-endowering agents and cognitive perfor-mance in PWD, as well as providing a correlation between MMSE (Mini Mental State Examination) scores and available anthropometric data...
September 25, 2017: Current Alzheimer Research
https://www.readbyqxmd.com/read/28942263/child-protection-and-the-development-of-child-abuse-pediatrics-in-new-york-city
#14
Vincent J Palusci
The history of child abuse pediatrics reflects the development of medicine as a profession influenced by social movements reacting to poverty, economic exploitation, and child maltreatment. As physicians began to specialize in caring for children, egregious cases led them to recognize children were affected by special medical problems and diseases which were compounded by poor conditions and abuse and neglect. They developed the fields of pediatrics and child abuse pediatrics to advocate for their needs in courts and communities...
September 14, 2017: Journal of Forensic and Legal Medicine
https://www.readbyqxmd.com/read/28942078/tau-protein-mapt-as-a-possible-biochemical-marker-of-traumatic-brain-injury-in-postmortem-examination
#15
Mieszko Olczak, Justyna Niderla-Bielińska, Magdalena Kwiatkowska, Dorota Samojłowicz, Sylwia Tarka, Teresa Wierzba-Bobrowicz
MAPT is a neuronal protein that plays an important role in axonal stabilization, neuronal development, and neuronal polarity. MAPT release into the CSF and blood has been interpreted as indicative of axonal injury as its elevated levels were observed in olympic boxers even after a mild head trauma suggesting minor CNS injuries. In our study we wanted to check the potential relevance of MAPT examination for forensic purposes. The study was carried out using cases of head injury group and cases of sudden death (cardiopulmonary failure, no injuries of the head - control group) provided by forensic pathologists at the Department of Forensic Medicine, Medical University of Warsaw...
September 15, 2017: Forensic Science International
https://www.readbyqxmd.com/read/28940226/the-effect-of-leprotic-infection-on-the-risk-of-death-in-medieval-rural-denmark
#16
K Saige Kelmelis, Michael Holton Price, Jim Wood
INTRODUCTION: Paleopathological studies of leprosy in Danish skeletal collections show that many individuals suffered from this stigmatized disease during the Middle Ages. This study examines the risk of death associated with leprotic infection in individuals from the Danish rural cemetery of Øm Kloster (AD 1172-1536). Specifically, we modeled the influence of leprotic infection on age-specific mortality accounting also for sex and social status (lay person / monastic). MATERIALS AND METHODS: The sample consisted of 311 adult individuals from the Øm Kloster skeletal collection housed at the Institute of Forensic Medicine, University of Southern Denmark (ADBOU)...
September 22, 2017: American Journal of Physical Anthropology
https://www.readbyqxmd.com/read/28938132/development-and-validation-of-carbofuran-and-3-hydroxycarbofuran-analysis-by-high-pressure-liquid-chromatography-with-diode-array-detector-hplc-dad-for-forensic-veterinary-medicine
#17
Vagner Gonçalves, Nicolle Queiroz Hazarbassanov, Adriana de Siqueira, Jorge Camilo Florio, Claudia Helena Pastor Ciscato, Paulo Cesar Maiorka, André Rinaldi Fukushima, Helenice de Souza Spinosa
Agricultural pesticides used with the criminal intent to intoxicate domestic and wild animals are a serious concern in Veterinary Medicine. In order to identify the pesticide carbofuran and its metabolite 3- hydroxycarbofuran in animals suspected of exogenous intoxication a high pressure liquid chromatography with diode array detector (HPLC-DAD) method was developed and validated in stomach contents, liver, vitreous humor and blood. The method was evaluated using biological samples from seven different animal species...
September 14, 2017: Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences
https://www.readbyqxmd.com/read/28933678/medicine-madness-and-murderers-the-context-of-english-forensic-psychiatric-hospitals
#18
Ruth McDonald, Vivek Furtado, Birgit Völlm
Purpose The purpose of this paper is to add to the understanding of context by shedding light on the relationship between context and organisational actors' abilities to resolve ongoing challenges. Design/methodology/approach The authors used qualitative data collection (interviews and focus groups with staff and site visits to English forensic psychiatry hospitals) and the analysis was informed by Lefebvre's writings on space. Findings Responses to ongoing challenges were both constrained and facilitated by the context, which was negotiated and co-produced by the actors involved...
August 21, 2017: Journal of Health Organization and Management
https://www.readbyqxmd.com/read/28933558/-oncology-secrets-of-suddenly-deceased-individuals
#19
Kateřina Stoklásková, Miroslav Ďatko, Eva Daňková, Milan Votava, Karel Schneller, Martin Zeman, Tomáš Vojtíšek, Michal Zelený
Malignant neoplasms represent the second most common cause of death in men and women in the Czech Republic after cardiovascular diseases. The incidence, prevalence and mortality is recorded in the Czech National Cancer Registry. The most recent data available is from 2013, in this year there were 81 541 patients newly diagnosed with cancer and 26 944 people died of cancer. From a long-term perspective, the incidence of neoplasms is increasing and the mortality is decreasing. In the Institute of Forensic Medicine in Brno there were 480 cases of newly reported malignant tumors during the period 2010-2015, which were not known before the autopsy...
2017: Soudní Lékarství
https://www.readbyqxmd.com/read/28926821/autopsies-in-the-elderly-erzurum-study
#20
Ozge Timur, Pinar Tosun Tasar, Merve Gulsah Ulusoy, Azem Irez, Filiz Yildirim, Dogan Nasir Binici, Sevnaz Sahin, Ahmet Nezih Kok
INTRODUCTION: Clinical and forensic autopsies are the best methods for determining cause of death. The aim of this study was to determine demographic and etiologic characteristics in geriatric forensic cases analyzed in Erzurum, Turkey. MATERIALS AND METHODS: Autopsy reports and prosecution documents of decedents aged 65 and older autopsied in the Morgue Specialization Department of the Forensic Medicine Institute, Erzurum Division between January 1, 2010 and December 31, 2015 were screened retrospectively...
September 12, 2017: Journal of Forensic and Legal Medicine
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