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forensic medicin

Hoover Quitian-Reyes, Carlos Gómez-Restrepo, Maria Juliana Gómez, Salome Naranjo, Patricia Heredia, John Villegas
OBJECTIVE: This study aimed to quantify the number of years of life lost (YLL) in traffic accidents in Bogota, Colombia. STUDY DESIGN AND SETTING: The years of life lost were calculated using the 'age-standardized expected years of life lost' method, the table of Japanese adjusted life expectancy and the database of the Institute of Legal Medicine and Forensic Science between September 2012 and August 2013. RESULTS: During a period of one year, 430 people died and 10,056...
October 19, 2016: Journal of Clinical Epidemiology
Borisav Stojanović, Ljiljana Vasović, Slobodan Vlajković, Milena Trandafilović, Marija Mladenović
A specificity of the vertebrobasilar system (VBS) is a convergent junction of paired vertebral arteries (VAs) in the basilar artery (BA) usually at the level of bulbopontine sulcus on the ventral side of the rhombencephalon. We revealed multiple VBS variations (a high junction of both VAs, absence of posterior inferior cerebellar arteries, short and ectatic BA, hypoplasia and initial duplication of the left anterior inferior cerebellar artery, and bilateral common trunks of the posterior cerebral and superior cerebellar arteries) in a 52-year-old male that routinely autopsied at the Institute of Forensic Medicine...
October 21, 2016: Surgical and Radiologic Anatomy: SRA
Lotta Walz, Anna K Jönsson, Brita Zilg, Carl Johan Östgren, Henrik Druid
AIMS/HYPOTHESIS: The aim of this study was to identify risk factors associated with confirmed fatal hyperglycaemia, which could predispose potentially preventable deaths in individuals on glucose lowering drugs. METHODS: A retrospective register-based case-control study conducted on a nationwide cohort with individuals who died due to hyperglycaemia as determined by forensic postmortem examination, in Sweden August 2006 to December 2012. Vitreous glucose was used to diagnose hyperglycaemia postmortem...
2016: PloS One
Carlos Cardoso-Palacios, Ingela Lanekoff
Counterfeit pharmaceutical drugs imply an increasing threat to the global public health. It is necessary to have systems to control the products that reach the market and to detect falsified medicines. In this work, molecules in several pharmaceutical tablets were directly analyzed using nanospray desorption electrospray ionization mass spectrometry (nano-DESI MS). Nano-DESI is an ambient surface sampling technique which enables sampling of molecules directly from the surface of the tablets without any sample pretreatment...
2016: Journal of Analytical Methods in Chemistry
Taner Daş, Aytül Sargan, Gülhan Yağmur, Muzaffer Yildirim, Cumhur Selçuk Topal, Ahmet Selçuk Gürler, Hizir Asliyüksek, Murat Nihat Arslan, Rifat Özdemirel
Lower respiratory infections are commonly due to viruses and are the third largest cause of death. Respiratory tract viruses have a tendency to target the specific regions in the lung and can harm the host via direct effect of the virus and the host's inflammatory response. In this study, relationships between morphologic changes in the lung and the viral agent type isolated in the lung by the polymerase chain reaction technique were investigated. This study was performed retrospectively at 113 autopsy cases in the Council of Forensic Medicine in Istanbul...
October 7, 2016: American Journal of Forensic Medicine and Pathology
Manal H Abdel Aziz, Fatma M M Badr El Dine, Nourhan M M Saeed
INTRODUCTION: Identification of sex and ethnicity has always been a challenge in the fields of forensic medicine and criminal investigations. Fingerprinting and DNA comparisons are probably the most common techniques used in this context. However, since they cannot always be used, it is necessary to apply different and less known techniques such as lip prints. AIM OF THE WORK: Is to study the pattern of lip print in Egyptian and Malaysian populations and its relation to sex and populations difference...
October 8, 2016: Journal of Forensic and Legal Medicine
Min-Zhu Zhao, Yong-Guo Li, Peng Zhang, Jin-Cheng Xiong, Shi-Sheng Zhu, Xuan Xiao, Jian-Bo Li
In forensic medicine, the diagnosis of death due to neurogenic shock is considered to be an aporia, as lacking objective indicators and presenting atypical symptoms in autopsy. Medico-legal disputes and complaints occasionally result from this ambiguity. To explore potential objective indicators of neurogenic shock, we set up a model of neurogenic shock by applying an external mechanical force on the carotid sinus baroreceptor in rabbits. The serum atrial natriuretic peptide (ANP) level was measured by radioimmunoassay in the control group (n = 8), survival group (n = 15) and death group (n = 5) both before and after the insult...
October 10, 2016: International Journal of Legal Medicine
Katalin Solymosi, Attila Köfalvi
Cannabis is one of the earliest cultivated plants. Cannabis of industrial utility and culinary value is generally termed as hemp. Conversely, cannabis that is bred for medical, spiritual and recreational purposes is called marijuana. The female marijuana plant produces a significant quantity of bio- and psychoactive phytocannabinoids, which regained the spotlight with the discovery of the endocannabinoid system of the animals in the early 90's. Nevertheless, marijuana is surrounded by controversies, debates and misconceptions related to its taxonomic classification, forensic identification, medical potential, legalization and its long-term health consequences...
October 4, 2016: Mini Reviews in Medicinal Chemistry
Asing, Md Eaqub Ali, Sharifah Bee Abd Hamid, M A Motalib Hossain, Shuhaimi Mustafa, Md Abdul Kader, I S M Zaidul
The Malayan box turtle (Cuora amboinensis) (MBT) is a vulnerable and protected turtle species, but it is a lucrative item in the illegal wildlife trade because of its great appeal as an exotic food item and in traditional medicine. Although several polymerase chain reaction (PCR) assays to identify MBT by various routes have been documented, their applicability for forensic authentication remains inconclusive due to the long length of the amplicon targets, which are easily broken down by natural decomposition, environmental stresses or physiochemical treatments during food processing...
2016: PloS One
Kazutaka Yamada, Fumio Sato, Noriyuki Horiuchi, Tohru Higuchi, Yoshiyasu Kobayashi, Naoki Sasaki, Yasuo Nambo
Autopsy imaging (Ai), postmortem imaging before necropsy, is used in human forensic medicine. Ai was performed using computed tomography (CT) for a 1-month-old Thoroughbred foal cadaver found in a pasture. CT revealed pericardial effusion, collapse of the aorta, bleeding in the lung lobe, gas in the ventricles and liver parenchyma, and distension of the digestive tract. Rupture in the left auricle was confirmed by necropsy; however, it was not depicted on CT. Therefore, Ai and conventional necropsy are considered to complement each other...
2016: Journal of Equine Science
Kim Brøsen, Stig Ejdrup Andersen, Jeanett Borregaard, Hanne Rolighed Christensen, Palle Mark Christensen, Kim Peder Dalhoff, Per Damkier, Jesper Hallas, Jens Heisterberg, Niels Jessen, Gesche Jürgens, Jens Peter Konnerup Kampmann, Britt Elmedal Laursen, Torben Laursen, Lars Peter Nielsen, Birgitte Klindt Poulsen, Henrik Enghusen Poulsen, Ljubica Vukelic Andersen, Thomas Senderovitz, Jesper Sonne
The Danish Society of Clinical Pharmacology was founded in 1976, and mainly thanks to the persistent efforts of the Society, clinical pharmacology became an independent medical speciality in Denmark in 1996. Since then, clinical pharmacology has gone from strength to strength. In the Danish health care system, clinical pharmacology has established itself as an indispensible part of the efforts to promote the rational, safe and economic use of drugs. Clinical pharmacologists are active in drug committees in both hospitals and in the primary sector...
September 29, 2016: Basic & Clinical Pharmacology & Toxicology
M Kobek, R Skowronek, C Jabłoński, Z Jankowski, A Pałasz
On 28 January 2003 snow avalanche in the Polish Tatras happened, in which 8 people died and 5 were injured. We tried to determine cause and manner of death in 6 fatal victims instead of advanced late post mortem changes in internal organs. Taking into consideration the circumstances of death, we paid special attention to histopathological examination of lungs, extended by Gomori's and AZAN staining. Pattern of the changes was similar to those observed in forensic medicine in cases of asphyxia due to airway obstruction and/or immobilization of chest and abdomen (Perthes' syndrome)...
2016: Archiwum Medycyny Sa̧dowej i Kryminologii
Sofie Lindgren Christiansen, Christin Løth Hertz, Laura Ferrero-Miliani, Morten Dahl, Peter Ejvin Weeke, LuCamp, Gyda Lolk Ottesen, Rune Frank-Hansen, Henning Bundgaard, Niels Morling
In forensic medicine, one-third of the sudden deaths remain unexplained after medico-legal autopsy. A major proportion of these sudden unexplained deaths (SUD) are considered to be caused by inherited cardiac diseases. Sudden cardiac death (SCD) may be the first manifestation of these diseases. The purpose of this study was to explore the yield of next-generation sequencing of genes associated with SCD in a cohort of SUD victims. We investigated 100 genes associated with cardiac diseases in 61 young (1-50 years) SUD cases...
September 21, 2016: European Journal of Human Genetics: EJHG
Andrea Porzionato, Veronica Macchi, Carla Stecco, Marios Loukas, R Shane Tubbs, Raffaele De Caro
Forensic Clinical Anatomy is a new practical application of the discipline of Clinical Anatomy for ascertaining and evaluating medico-legal questions. In particular, individual anatomy (normal anatomy, anatomical variations, age-, disease- or surgery-related modifications) can acquire significant relevance in various fields of legal medicine such as child abuse, sudden death, medical responsibility and/or liability, personal injury and damage. Anatomical data of forensic interest frequently arise from the correct application of methods of ascertainment; anatomical methods may then be required for further comprehensive analysis...
September 20, 2016: Clinical Anatomy
Elham Bazmi, Behnam Behnoush, Maryam Akhgari, Leila Bahmanabadi
OBJECTIVE: Benzodiazepines are frequently screened drugs in emergency toxicology, drugs of abuse testing, and in forensic cases. As the variations of benzodiazepines concentrations in biological samples during bleeding, postmortem changes, and redistribution could be biasing forensic medicine examinations, hence selecting a suitable sample and a validated accurate method is essential for the quantitative analysis of these main drug categories. The aim of this study was to develop a valid method for the determination of four benzodiazepines (flurazepam, lorazepam, alprazolam, and diazepam) in vitreous humor using liquid-liquid extraction and high-performance liquid chromatography...
2016: SAGE Open Medicine
H Dokgöz, M Yılmaz, N Türkmen, E Özer, M A Sungur, R Yılmaz
Objectives: This investigation was performed to determine opinions of forensic medicine specialists about concept of death. Methods: This descriptive, cross-sectional and qualitative study was performed on 103 forensic medicine specialists who consented to participate in the study between 2011-2012. Data were recruited during face-to-face interviews and via e-mail. Results: Forensic medicine specialists participated in this study were mostly (74...
January 26, 2016: West Indian Medical Journal
E Z Epsi, M Khalil, S Mannan, M S Azam, Z Ahmed, S Farjan, A Kabir, I Ara, S Ajmery, U K Zaman, S Amin
Now a days, benign prostatic hyperplasia and carcinoma of the prostate are the most common disorders in men. A cross sectional descriptive study was conducted in Department of Anatomy, Mymensingh Medical College, Mymensingh to find out the difference in weight of the prostate gland of Bangladeshi people in relation to age. The present study was performed on 67 postmortem human prostate gland collected from the morgue in the Department of Forensic Medicine, Mymensingh Medical College by non random purposive sampling technique...
July 2016: Mymensingh Medical Journal: MMJ
David T Mage, Maria Luisa Latorre, Alejandro G Jenik, E Maria Donner
INTRODUCTION: The cause of the sudden infant death syndrome (SIDS) is perhaps the oldest of unsolved mysteries of medicine, possibly dating back to Exodus in Biblical times when Egyptian children died in their sleep as if from a plague. It occurs when infants die unexpectedly with no sufficient cause of death found in a forensic autopsy, including death scene investigation and review of medical history. That SIDS is an X-linked recessive death from infectious respiratory disease of a physiologically anemic infant and not a simple anomalous cardiac or neurological condition is an extraordinary claim that requires extraordinary evidence...
2016: Frontiers in Neurology
İbrahim Üzün, Erdinç Özdemir, İpek Esen Melez, Deniz Oğuzhan Melez, Adem Akçakaya
BACKGROUND: General surgery is one of the branches in which the distinction between complication and malpractice is difficult to distinguish. In this study, presentation of the main forensic medical parameters considered for the evaluation of medical malpractice in cases of general surgery deaths in which medical malpractice has been alleged and discussing related concepts through the literature are aimed. METHODS: Allegations of medical malpractice against general surgery physicians sent to the First Forensic Expertise Board of the Council of Forensic Medicine between January 1, 2012 and December 31, 2013 for which the relation of casuality between medical malpractice and death had been determined were retrospectively evaluated...
July 2016: Ulusal Travma Ve Acil Cerrahi Dergisi, Turkish Journal of Trauma & Emergency Surgery: TJTES
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