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https://www.readbyqxmd.com/read/29771887/-new-visual-field-testing-possibilities-a-preliminary-report
#1
V P Erichev, A P Ermolaev, A A Antonov, G L Grigoryan, D V Kosova
There are currently no portable mobile perimeters that allow visual field testing outside ophthalmologist's examination rooms. PURPOSE: To develop a mobile perimetry technique based on use of a virtual reality headset (VR). MATERIAL AND METHODS: The study involved 26 patients (30 eyes) with II-III stage primary open-angle glaucoma (POAG) with compensated IOP. Perimetry was performed for each patient twice - on Humphrey analyzer (test 30-2, 76 points) and employing similar strategy on a perimeter integrated into VR headset (Total Vision, Russia)...
2018: Vestnik Oftalmologii
https://www.readbyqxmd.com/read/29770943/contamination-of-scots-pine-forests-with-polycyclic-aromatic-hydrocarbons-on-the-territory-of-industrial-city-of-siberia-russia
#2
Olga Vladimirovna Kalugina, Tatiana Alekseevna Mikhailova, Olga Vladimirovna Shergina
Anthropogenic contamination with polycyclic aromatic hydrocarbons (PAH) coming from a powerful aluminum smelter has been estimated by the accumulation of these substances (17 substances: phenanthrene, fluoranthene, pyrene, chrysene, acenaphthylene, acenaphthene, anthracene, fluorene, benz[а]anthracene, benz[b]fluoranthene, benz[k]fluoranthene, benz[а]pyrene, benz[е]pyrene, perylene, indeno[1,2,3-c,d]pyrene, benz[g,h,i]perylene, dibenz[a,h]anthracene) in needles of Scots pine (Pinus sylvestris L.) in the residential areas of Bratsk, East Siberia, Russia...
May 17, 2018: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29762255/ombitasvir-paritaprevir-ritonavir-dasabuvir-ribavirin-for-chronic-hepatitis-c-virus-genotype-1b-infected-cirrhotics-turquoise-iv
#3
Vasily Isakov, Dzmitry Paduta, Rolando M Viani, Jeffrey V Enejosa, Viktor Pasechnikov, Olga Znoyko, Pavel Ogurtsov, Pavel O Bogomolov, Marina V Maevskaya, Xiaotian Chen, Nancy S Shulman
OBJECTIVE: An estimated 336 per 100 000 people in Russia are infected with hepatitis C virus, including up to 75% with genotype (GT) 1b. In the TURQUOISE-II/-III trials, a 12-week regimen of the direct-acting antiviral agents ombitasvir (OBV), paritaprevir (PTV), ritonavir, and dasabuvir (DSV) in GT1b-infected patients with compensated cirrhosis resulted in 12-week sustained virologic response (SVR) rates of 100%. PATIENTS AND METHODS: In TURQUOISE-IV, GT1b-infected patients (n=36) from Russia and Belarus with compensated cirrhosis, who were treatment naive or previously treated with pegylated interferon/ribavirin (RBV), received OBV/PTV/ritonavir+DSV+RBV for 12 weeks...
May 14, 2018: European Journal of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/29761174/elbasvir-grazoprevir-in-asia-pacific-russian-participants-with-chronic-hepatitis-c-virus-genotype-1-4-or-6-infection
#4
Jacob George, Eduard Burnevich, I-Shyan Sheen, Jeong Heo, Nguyen Van Kinh, Tawesak Tanwandee, Pin-Nan Cheng, Do Young Kim, Won Young Tak, Svetlana Kizhlo, Konstantin Zhdanov, Vasily Isakov, Liwen Liang, Pauline Lindore, Joy Ginanni, Bach-Yen Nguyen, Janice Wahl, Eliav Barr, Michael Robertson, Paul Ingravallo, Rohit Talwani
The prevalence of hepatitis C virus (HCV) infection in Asian countries is high. This study assessed the efficacy and safety of elbasvir/grazoprevir (EBR/GZR) in participants with HCV infection from Asia-Pacific countries and Russia. In this phase 3, randomized, placebo-controlled, double-blind study, treatment-naive participants with HCV genotype (GT) 1, 4, or 6 infection were randomized to EBR 50 mg/GZR 100 mg (immediate-treatment group [ITG]) or placebo (deferred-treatment group [DTG]) once daily for 12 weeks (Protocol PN-5172-067, NCT02251990)...
May 2018: Hepatology Communications
https://www.readbyqxmd.com/read/29759087/antechiniella-septentrionalis-n-sp-spirurida-acuariidae-a-new-intestinal-nematode-parasite-of-the-tundra-vole-microtus-oeconomus-pallas-rodentia-muridae-in-the-north-east-of-russia
#5
E S Ivanova, N E Dokuchaev, S E Spiridonov
Antechiniella septentrionalis n. sp. (Spirurida: Acuariidae) is described from the duodenum of a tundra vole, Microtus oeconomus (Pallas), collected in the Magadan region in the north-east part of Russia. It differs from A. suffodiax (Beveridge & Barker, 1975) and A. sertatum Smales, 1991 mainly in having a larger number of postcloacal papillae (5-6 pairs vs 4 pairs), a differently shaped left spicule, the disposition of precloacal papillae in two rows vs one, and oblong vs oval eggs. Other differences include the different disposition of ovaries in A...
May 15, 2018: Journal of Helminthology
https://www.readbyqxmd.com/read/29758855/ratios-of-greenhouse-gas-emissions-observed-over-the-yellow-sea-and-the-east-china-sea
#6
Yunsong Liu, Lingxi Zhou, Pieter P Tans, Kunpeng Zang, Siyang Cheng
During a cruise of the survey vessel Dongfanghong II on the Yellow Sea and the East China Sea in the spring of 2017 we performed accurate measurements of the mole fractions of carbon dioxide (CO2 ), methane (CH4 ), carbon monoxide (CO) and nitrous oxide (N2 O) using two types of Cavity Ring-Down Spectrometers (CRDS). The spatial variations of the mole fraction of the four trace gases were very similar. The emission sources of these gases were divided into several regions by using the NOAA HYSPLIT model. Then we analyzed the variations of the ratios of the mole fraction enhancements between every pair of trace gases downwind of these source areas...
August 15, 2018: Science of the Total Environment
https://www.readbyqxmd.com/read/29756455/characterization-of-the-transmitted-virus-in-an-ongoing-hiv-1-epidemic-driven-by-injecting-drug-use
#7
Elena Dukhovlinova, Alexey Masharsky, Aleksandra Vasileva, Alessandro Porrello, Shuntai Zhou, Olga Toussova, Sergei Verevochkin, Ekaterina Akulova, Dmitrij Frishman, David Montefiori, Celia Labranche, Irving Hoffman, William Miller, Myron S Cohen, Andrei Kozlov, Ronald Swanstrom
Understanding features of the HIV-1 transmission process have the potential to inform biological interventions for prevention. We have examined the transmitted virus in a cohort of people who inject drugs and who are at risk of HIV-1 infection through blood contamination when injecting in a group. This study focused on seven newly infected participants in St. Petersburg, Russia, who were in acute or early infection. We used end-point dilution PCR to amplify single viral genomes to assess the complexity of the transmitted virus...
May 14, 2018: AIDS Research and Human Retroviruses
https://www.readbyqxmd.com/read/29755976/a-general-safety-assessment-for-purified-food-ingredients-derived-from-biotechnology-crops-case-study-of-brazilian-sugar-and-beverages-produced-from-insect-protected-sugarcane
#8
Reese D Kennedy, Adriana Cheavegatti-Gianotto, Wladecir S de Oliveira, Ronald P Lirette, Jerry J Hjelle
Insect-protected sugarcane that expresses Cry1Ab has been developed in Brazil. Analysis of trade information has shown that effectively all the sugarcane-derived Brazilian exports are raw or refined sugar and ethanol. The fact that raw and refined sugar are highly purified food ingredients, with no detectable transgenic protein, provides an interesting case study of a generalized safety assessment approach. In this study, both the theoretical protein intakes and safety assessments of Cry1Ab, Cry1Ac, NPTII, and Bar proteins used in insect-protected biotechnology crops were examined...
2018: Frontiers in Bioengineering and Biotechnology
https://www.readbyqxmd.com/read/29755184/financial-and-emotional-support-in-close-personal-ties-among-central-asian-migrant-women-in-russia
#9
Olga Kornienko, Victor Agadjanian, Cecilia Menjívar, Natalia Zotova
This study advances research on the role of personal networks as sources of financial and emotional support in immigrants' close personal ties beyond the immediate family. Because resource scarcity experienced by members of immigrant communities is likely to disrupt normatively expected reciprocal support, we explored multi-level predictors of exchange processes with personal network members that involve (1) only receiving support, (2) only providing support, and (3) reciprocal support exchanges. We focus on an understudied case of Central Asian migrant women in the Russian Federation using a sample of 607 women from three ethnic groups-Kyrgyz, Tajik, Uzbek-who were surveyed in two large Russian cities-Nizhny Novgorod and Kazan...
May 2018: Social Networks
https://www.readbyqxmd.com/read/29753874/simulation-of-patient-flow-in-multiple-healthcare-units-using-process-and-data-mining-techniques-for-model-identification
#10
Sergey V Kovalchuk, Anastasia A Funkner, Oleg G Metsker, Aleksey N Yakovlev
INTRODUCTION: An approach to building a hybrid simulation of patient flow is introduced with a combination of data-driven methods for automation of model identification. The approach is described with a conceptual framework and basic methods for combination of different techniques. The implementation of the proposed approach for simulation of the acute coronary syndrome (ACS) was developed and used in an experimental study. METHODS: A combination of data, text, process mining techniques, and machine learning approaches for the analysis of electronic health records (EHRs) with discrete-event simulation (DES) and queueing theory for the simulation of patient flow was proposed...
May 10, 2018: Journal of Biomedical Informatics
https://www.readbyqxmd.com/read/29751428/molecular-composition-of-raw-peat-and-humic-substances-from-permafrost-peat-soils-of-european-northeast-russia-as-climate-change-markers
#11
Roman Vasilevich, Evgeny Lodygin, Vasily Beznosikov, Evgeny Abakumov
Humic substances (HSs) from the mire peat soils of the forest-tundra zone of the European northeast part of Russia have been characterized in terms of molecular composition. This was accomplished using solid-state 13 C nuclear magnetic resonance (13 C NMR) techniques and electron spin resonance (ESR) spectroscopy. The composition depended on the intensity of cryogenic processes in the active layer, the quality of the humification precursors (the degree of peat material transformation), and the biochemical selection of aromatic fragments during humification...
February 15, 2018: Science of the Total Environment
https://www.readbyqxmd.com/read/29749378/frequency-and-associated-factors-of-bone-fractures-in-russians-the-ural-eye-and-medical-study
#12
Mukharram M Bikbov, Rinat R Fayzrakhmanov, Gyulli M Kazakbaeva, Rinat M Zainullin, Venera F Salavatova, Timur R Gilmanshin, Inga I Arslangareeva, Nikolai A Nikitin, Songhomitra Panda-Jonas, Svetlana R Mukhamadieva, Dilya F Yakupova, Renat I Khikmatullin, Said K Aminev, Ildar F Nuriev, Artur F Zaynetdinov, Yulia V Uzianbaeva, Jost B Jonas
With information about frequency of bone fractures in Russia mostly missing, we assessed the frequency of previous bone fractures in a Russian population. The population-based study Ural Eye and Medical Study included 5899 (80.5%) out of 7328 eligible individuals (mean age: 59.0 ± 10.7 years; range: 40-94 years). The history of previous bone fractures was assessed in a standardized interview for 5397 (91.5%) individuals. Mean frequency of any previous bone fracture was 1650/5397 (30.6%; 95% confidence interval (CI): 29, 3, 31...
May 10, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29749049/epidemiological-characterization-of-lumpy-skin-disease-outbreaks-in-russia-in-2016
#13
A Sprygin, E Artyuchova, Y Babin, P Prutnikov, E Kostrova, O Byadovskaya, A Kononov
In 2015, the lumpy skin disease virus spread throughout the Russian Federation. Following a modified stamping-out campaign, the disease re-emerged with a greater incidence across 16 regions of Southern and Central Russia. A total of 313 outbreaks were reported to OIE. The highest outbreak frequency was observed in the republics of Chechnya (108), Kalmykiya (57), and Ingushetiya (35). The disease cases predominantly occurred in June and July 2016, starting from May to December; however, no association between outbreaks and altitudes was identified (p > ...
May 10, 2018: Transboundary and Emerging Diseases
https://www.readbyqxmd.com/read/29747573/global-evolution-and-phylogeography-of-brucella-melitensis-strains
#14
Sergey V Pisarenko, Dmitry A Kovalev, Anna S Volynkina, Dmitry G Ponomarenko, Diana V Rusanova, Nina V Zharinova, Anna A Khachaturova, Lyudmila E Tokareva, Irina G Khvoynova, Alexander N Kulichenko
BACKGROUND: Brucellosis is a bacterial zoonotic disease. Annually in the world more than 500,000 new cases of brucellosis in humans are registered. In this study, we propose an evolutionary model of the historical distribution of B. melitensis based on the full-genomic SNP analysis of 98 strains. RESULTS: We performed an analysis of the SNP of the complete genomes of 98 B. melitensis strains isolated in different geographical regions of the world to obtain relevant information on the population structure, genetic diversity and the evolution history of the species...
May 10, 2018: BMC Genomics
https://www.readbyqxmd.com/read/29745040/first-detection-of-foot-and-mouth-disease-virus-o-me-sa-ind2001-in-china
#15
Z Zhu, F Yang, J He, J Li, W Cao, J Li, Y Xia, J Guo, Y Jin, K Zhang, H Zheng, X Liu
Foot-and-mouth disease (FMD) is endemic in China and is predominantly due to foot-and-mouth disease virus (FMDV) serotype O Mya-98 lineage. In recent years, FMDV O/ME-SA/Ind2001 lineage has spread from the Indian subcontinent to South-East Asia, Middle East and Africa, which may pose potential threats for future trans-regional livestock movements. In this study, we identified the appearance of FMDV O/ME-SA/Ind2001 in China; the first time that this virus lineage has been found there. Sequencing and phylogenetic analysis of VP1 sequences revealed that this newly determined strain belongs to O/ME-SA/Ind2001 sublineage d and is closely related to strains that have caused recent outbreaks of FMD in Nepal, Myanmar, Russia and South Korea...
May 9, 2018: Transboundary and Emerging Diseases
https://www.readbyqxmd.com/read/29742471/the-impact-of-initial-antibiotic-treatment-failure-real-world-insights-in-healthcare-associated-or-nosocomial-pneumonia
#16
Kellie Ryan, Sudeep Karve, Pascale Peeters, Elisa Baelen, Danielle Potter, Sonia Rojas-Farreras, Esther Pascual, Jesús Rodríguez-Baño
OBJECTIVES: To assess real-world treatment patterns and clinical outcomes associated with initial antibiotic therapy (IAT, antibiotics received ≤48 h post-initiation of antibiotic therapy), including level of IAT failure, and potential risk factors for IAT failure in healthcare-associated infections. METHODS: Data were obtained from medical records of adult patients hospitalized with healthcare-associated pneumonia (HCAP) and nosocomial pneumonia (NP), including ventilator-associated pneumonia, from 1 July 2013 - 30 June 2014 in Brazil, France, Italy, Russia and Spain during the retrospective, observational study, RECOMMEND (NCT02364284; D4280R00005)...
May 6, 2018: Journal of Infection
https://www.readbyqxmd.com/read/29742014/complete-genomic-characterization-of-three-tick-borne-encephalitis-viruses-detected-along-the-china-north-korea-border-2011
#17
Xiaoxia He, Junwei Zhao, Shihong Fu, Lisi Yao, Xiaoyan Gao, Yan Liu, Ying He, Guodong Liang, Huanyu Wang
Tick-borne encephalitis virus (TBEV) causes neurological infections with serious sequelae in Europe and Northeast Asia. In China, the major epidemic areas are along the borders with Russia and North Korea. Although several TBEV isolates have been reported, the biological characteristics of the Chinese strains, especially those along the China-North Korea border, are unclear. In this study, we detected seven TBEV fragment sequences in 602 adult Dermacentor silvarum collected in the Changbai Mountain area of Jilin Province on the China-North Korea border and characterized the genome of three TBEV strains (JLCB11-08, JLCB11-35, and JLCB11-40)...
May 9, 2018: Vector Borne and Zoonotic Diseases
https://www.readbyqxmd.com/read/29732508/bird-diversity-and-dissimilarity-show-contrasting-patterns-along-heavy-metal-pollution-gradients-in-the-urals-russia
#18
Eugen A Belskii, Vladimir S Mikryukov
The effects of industrial pollution on bird diversity have been widely studied using traditional diversity measures, which assume all species to be equivalent. We compared species richness and Shannon index with distance-based measures of taxonomic, functional, and phylogenetic diversity (the abundance-weighted mean nearest taxon distances), which describe within-community dissimilarity at terminal branches. Analysis of dissimilarity can shed light on the processes underlying community assembly, i.e., environmental filtering decreases dissimilarity whereas competitive exclusion increases it...
May 7, 2018: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29730584/correlates-of-frequent-alcohol-consumption-among-middle-aged-and-older-men-and-women-in-russia-a-multilevel-analysis-of-the-privmort-retrospective-cohort-study
#19
Alexi Gugushvili, Aytalina Azarova, Darja Irdam, Whitney Crenna-Jennings, Michael Murphy, Martin McKee, Lawrence King
BACKGROUND: A large proportion of premature deaths in Russia since the early 1990s, following the transition from communism, have been attributed to hazardous drinking. Little is known about the correlates of alcohol consumption. We present new data on the consumption of alcoholic beverages among middle-aged and older Russians and identify socio-demographic, socio-economic, and life-course correlates of frequent drinking. METHODS: Within the framework of the PrivMort project, conducted in 30 industrial towns in the European part of Russia, we acquired information on the frequency of drinking among 22,796 respondents and 57,907 of their surviving and deceased relatives...
May 1, 2018: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/29729048/regional-variations-in-definitions-and-rates-of-hypoglycaemia-findings-from-the-global-hat-observational-study-of-27-585-people-with-type-1-and-insulin-treated-type-2-diabetes-mellitus
#20
K Khunti, M Cigrovski Berković, B Ludvik, E Moberg, J Barner Lekdorf, H Gydesen, U Pedersen-Bjergaard
AIM: To determine participant knowledge and reporting of hypoglycaemia in the non-interventional Hypoglycaemia Assessment Tool (HAT) study. METHODS: HAT was conducted in 24 countries over a 6-month retrospective/4-week prospective period in 27 585 adults with Type 1 or insulin-treated Type 2 diabetes mellitus. Participants recorded whether hypoglycaemia was based on blood glucose levels, symptoms or both. RESULTS: Hypoglycaemia rates were consistently higher in the prospective compared with the retrospective period...
May 5, 2018: Diabetic Medicine: a Journal of the British Diabetic Association
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