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https://www.readbyqxmd.com/read/29245185/contribution-of-crop-model-structure-parameters-and-climate-projections-to-uncertainty-in-climate-change-impact-assessments
#1
Fulu Tao, Reimund P Rötter, Taru Palosuo, C G H Díaz-Ambrona, M Inés Mínguez, Mikhail A Semenov, Kurt Christian Kersebaum, Claas Nendel, Xenia Specka, Holger Hoffmann, Frank Ewert, Anaelle Dambreville, Pierre Martre, Lucía Rodríguez, Margarita Ruiz-Ramos, Thomas Gaiser, Jukka G Höhn, Tapio Salo, Roberto Ferrise, Marco Bindi, Davide Cammarano, Alan H Schulman
Climate change impact assessments are plagued with uncertainties from many sources, such as climate projections or the inadequacies in structure and parameters of the impact model. Previous studies tried to account for the uncertainty from one or two of these. Here, we developed a triple-ensemble probabilistic assessment using seven crop models, multiple sets of model parameters, and eight contrasting climate projections together to comprehensively account for uncertainties from these three important sources...
December 15, 2017: Global Change Biology
https://www.readbyqxmd.com/read/29245182/an-efficient-parallel-simulation-of-unsteady-blood-flows-in-patient-specific-pulmonary-artery
#2
Fande Kong, Vitaly Kheyfets, Ender Finol, Xiao-Chuan Cai
Simulation of blood flows in the pulmonary artery provides some insight into certain diseases by examining the relationship between some continuum metrics, e.g. the wall shear stress acting on the vascular endothelium, which responds to flow-induced mechanical forces by releasing vasodilators/constrictors. In [?kheyfets2015patient], V. Kheyfets studies numerically a patient-specific pulmonary circulation to show that decreasing wall shear stress is correlated with increasing pulmonary vascular impedance. In this paper, we develop a scalable parallel algorithm based on domain decomposition methods to investigate an unsteady model with patient specific pulsatile waveforms as the inlet boundary condition...
December 15, 2017: International Journal for Numerical Methods in Biomedical Engineering
https://www.readbyqxmd.com/read/29245102/random-responses-inflate-statistical-estimates-in-heavily-skewed-addictions-data
#3
Kevin M King, Dale S Kim, Connor J McCabe
BACKGROUND: Some respondents may respond at random to self-report surveys, rather than responding conscientiously (Meade and Craig, 2012), and this has only recently come to the attention of researchers in the addictions field (Godinho et al., 2016). Almost no research in the published addictions literature has reported screening for random responses. We illustrate how random responses can bias statistical estimates using simulated and real data, and how this is especially problematic in skewed data, as is common with substance use outcomes...
December 9, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/29245096/pre-and-post-operative-evaluation-of-pincer-type-femoroacetabular-impingement-during-squat-using-image-matching-techniques-a-case-report
#4
Kensei Yoshimoto, Satoshi Hamai, Hidehiko Higaki, Hirotaka Gondo, Satoru Ikebe, Yasuharu Nakashima
INTRODUCTION: Although combined evaluation of hip joint kinematics and bone morphology is necessary for accurate assessment of femoroacetabular impingement (FAI), there are no report which evaluated hip kinematics of pincer-type FAI. PRESENTATION OF CASE: The pre- and postoperative hip kinematics of a 46-year-old man, with a pincer-type FAI during squat were evaluated using image-matching techniques and the rim-neck distance was measured. Preoperative simulation of squatting was also performed using patient's bone models and healthy subject's kinematics data to detect the overlapping lesion between the acetabulum and the femur...
December 8, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/29245062/comparative-studies-on-dna-binding-and-in-vitro-antitumor-activity-of-enantiomeric-ruthenium-ii-complexes
#5
Wen-Xu Hong, Fengwen Huang, Tianwen Huan, Xu Xu, Qingguo Han, Gaofeng Wang, Hong Xu, Shan Duan, Yongheng Duan, Xun Long, Ying Liu, Zhangli Hu
A pair of ruthenium(II) complex enantiomers, Δ- and Λ-[Ru(bpy)2PBIP]2+ {bpy=2,2'-bipyridine, PBIP=2-(4-bromophenyl)imidazo[4,5-f]1,10-phenanthroline} have been synthesized and characterized. The systematic comparative studies between two enantiomers on their DNA binding-behaviors with calf thymus DNA (CT DNA) were carried out by viscosity measurements, spectrophotometric methods and molecular simulation technology. Additional assays were performed to explore the cytotoxicity of the ruthenium(II) enantiomers against tumor cell lines...
November 29, 2017: Journal of Inorganic Biochemistry
https://www.readbyqxmd.com/read/29244951/interfacial-adsorption-of-neutral-and-ionic-solutes-in-a-water-droplet
#6
Patrick K Wise, Dor Ben-Amotz
Direct (solute-water) and indirect (water-water) contributions to adsorption at an air-water interface are identified using the Widom potential distribution theorem and quantified using molecular dynamics simulations of a liquid water droplet containing either neopentane or iodide-like solutes with charges of 0 or ±1. The results are used to quantitatively compare direct and indirect, energetic and entropic, contributions to adsorption, as well as to critically test surface capillary wave, linear response (LR), and mean field (MF) predictions...
December 15, 2017: Journal of Physical Chemistry. B
https://www.readbyqxmd.com/read/29244866/molecular-dynamics-simulations-of-the-glucocorticoid-receptor-dna-binding-domain-suggest-a-role-of-the-lever-arm-mobility-in-transcriptional-output
#7
Lautaro Damián Álvarez, Diego Martín Presman, Adalí Pecci
One of the first and essential steps in gene expression regulation involves the recruitment of transcription factors (TFs) to specific response elements located at enhancers and/or promoters of targeted genes. These DNA elements have a certain variability in both sequence and length, which may affect the final transcriptional output. The molecular mechanisms in which TFs integrate the subtle differences within specific recognition sequences to offer different transcriptional responses is still largely unknown...
2017: PloS One
https://www.readbyqxmd.com/read/29244852/proteometabolomic-response-of-deinococcus-radiodurans-exposed-to-uvc-and-vacuum-conditions-initial-studies-prior-to-the-tanpopo-space-mission
#8
Emanuel Ott, Yuko Kawaguchi, Denise Kölbl, Palak Chaturvedi, Kazumichi Nakagawa, Akihiko Yamagishi, Wolfram Weckwerth, Tetyana Milojevic
The multiple extremes resistant bacterium Deinococcus radiodurans is able to withstand harsh conditions of simulated outer space environment. The Tanpopo orbital mission performs a long-term space exposure of D. radiodurans aiming to investigate the possibility of interplanetary transfer of life. The revealing of molecular machinery responsible for survivability of D. radiodurans in the outer space environment can improve our understanding of underlying stress response mechanisms. In this paper, we have evaluated the molecular response of D...
2017: PloS One
https://www.readbyqxmd.com/read/29244838/muscle-function-in-glenohumeral-joint-stability-during-lifting-task
#9
Yoann Blache, Mickaël Begon, Benjamin Michaud, Landry Desmoulins, Paul Allard, Fabien Dal Maso
Ensuring glenohumeral stability during repetitive lifting tasks is a key factor to reduce the risk of shoulder injuries. Nevertheless, the literature reveals some lack concerning the assessment of the muscles that ensure glenohumeral stability during specific lifting tasks. Therefore, the purpose of this study was to assess the stabilization function of shoulder muscles during a lifting task. Kinematics and muscle electromyograms (n = 9) were recorded from 13 healthy adults during a bi-manual lifting task performed from the hip to the shoulder level...
2017: PloS One
https://www.readbyqxmd.com/read/29244824/a-backwards-glance-at-words-using-reversed-interior-masked-primes-to-test-models-of-visual-word-identification
#10
Colin J Davis, Stephen J Lupker
The experiments reported here used "Reversed-Interior" (RI) primes (e.g., cetupmor-COMPUTER) in three different masked priming paradigms in order to test between different models of orthographic coding/visual word recognition. The results of Experiment 1, using a standard masked priming methodology, showed no evidence of priming from RI primes, in contrast to the predictions of the Bayesian Reader and LTRS models. By contrast, Experiment 2, using a sandwich priming methodology, showed significant priming from RI primes, in contrast to the predictions of open bigram models, which predict that there should be no orthographic similarity between these primes and their targets...
2017: PloS One
https://www.readbyqxmd.com/read/29244823/cost-effectiveness-of-national-health-insurance-programs-in-high-income-countries-a-systematic-review
#11
Son Nghiem, Nicholas Graves, Adrian Barnett, Catherine Haden
OBJECTIVES: National health insurance is now common in most developed countries. This study reviews the evidence and synthesizes the cost-effectiveness information for national health insurance or disability insurance programs across high-income countries. DATA SOURCES: A literature search using health, economics and systematic review electronic databases (PubMed, Embase, Medline, Econlit, RepEc, Cochrane library and Campbell library), was conducted from April to October 2015...
2017: PloS One
https://www.readbyqxmd.com/read/29244777/sparse-adaptive-iteratively-weighted-thresholding-algorithm-saita-for-lp-regularization-using-the-multiple-sub-dictionary-representation
#12
Yunyi Li, Jie Zhang, Shangang Fan, Jie Yang, Jian Xiong, Xiefeng Cheng, Hikmet Sari, Fumiyuki Adachi, Guan Gui
Both L1/2 and L2/3 are two typical non-convex regularizations of Lp (0<p<1), which can be employed to obtain a sparser solution than the L₁ regularization. Recently, the multiple-state sparse transformation strategy has been developed to exploit the sparsity in L₁ regularization for sparse signal recovery, which combines the iterative reweighted algorithms. To further exploit the sparse structure of signal and image, this paper adopts multiple dictionary sparse transform strategies for the two typical cases p∈{1/2, 2/3} based on an iterative Lp thresholding algorithm and then proposes a sparse adaptive iterative-weighted Lp thresholding algorithm (SAITA)...
December 15, 2017: Sensors
https://www.readbyqxmd.com/read/29244773/nanoscale-phase-evolution-during-continuum-decomposition-of-fe-cr-alloys
#13
Yongsheng Li, Lihui Zhu, Chengwei Liu, Shujing Shi
The continuum decomposition of the Fe-Cr alloys from initial phase separation to steady-state coarsening with concentrations varying from 25 at % Cr and 30 at % Cr to 33 at % Cr aged at 750 K was studied by utilizing three-dimensional phase-field simulations. The dynamic stages of separation of nanoscale Cr-enriched α' phase were distinguished by the evolution of the volume fraction, particle number density and the average particle radius of the α' phase. The stage of steady-state coarsening was characterized with an equilibrium volume fraction and decreasing particle number density...
December 15, 2017: Materials
https://www.readbyqxmd.com/read/29244762/towards-realistic-urban-traffic-experiments-using-dfrouter-heuristic-validation-and-extensions
#14
Jorge Luis Zambrano-Martinez, Carlos T Calafate, David Soler, Juan-Carlos Cano
Traffic congestion is an important problem faced by Intelligent Transportation Systems (ITS), requiring models that allow predicting the impact of different solutions on urban traffic flow. Such an approach typically requires the use of simulations, which should be as realistic as possible. However, achieving high degrees of realism can be complex when the actual traffic patterns, defined through an Origin/Destination (O-D) matrix for the vehicles in a city, remain unknown. Thus, the main contribution of this paper is a heuristic for improving traffic congestion modeling...
December 15, 2017: Sensors
https://www.readbyqxmd.com/read/29244750/higa-a-running-history-information-guided-genetic-algorithm-for-protein-ligand-docking
#15
Boxin Guan, Changsheng Zhang, Yuhai Zhao
Protein-ligand docking is an essential part of computer-aided drug design, and it identifies the binding patterns of proteins and ligands by computer simulation. Though Lamarckian genetic algorithm (LGA) has demonstrated excellent performance in terms of protein-ligand docking problems, it can not memorize the history information that it has accessed, rendering it effort-consuming to discover some promising solutions. This article illustrates a novel optimization algorithm (HIGA), which is based on LGA for solving the protein-ligand docking problems with an aim to overcome the drawback mentioned above...
December 15, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/29244727/an-efficient-estimator-for-moving-target-localization-using-multi-station-dual-frequency-radars
#16
Jiyan Huang, Ying Zhang, Shan Luo
Localization of a moving target in a dual-frequency radars system has now gained considerable attention. The noncoherent localization approach based on a least squares (LS) estimator has been addressed in the literature. Compared with the LS method, a novel localization method based on a two-step weighted least squares estimator is proposed to increase positioning accuracy for a multi-station dual-frequency radars system in this paper. The effects of signal noise ratio and the number of samples on the performance of range estimation are also analyzed in the paper...
December 15, 2017: Sensors
https://www.readbyqxmd.com/read/29244723/an-online-mfl-sensing-method-for-steel-pipe-based-on-the-magnetic-guiding-effect
#17
Jianbo Wu, Hui Fang, Xiaoming Huang, Hui Xia, Yihua Kang, Chaoqing Tang
In order to improve the sensitivity of online magnetic flux leakage (MFL) testing for steel pipe, a sensing method based on the magnetic guiding effect is proposed and investigated in this paper. Compared to the conventional contact sensing method using a non-ferromagnetic support, the proposed method creatively utilizes a ferromagnetic one to guide more magnetic flux to leak out. Based on Hopkinson's law, the principle of the magnetic guiding effect of the ferromagnetic support is theoretically illustrated...
December 15, 2017: Sensors
https://www.readbyqxmd.com/read/29244712/performance-analysis-of-a-novel-hybrid-s-aloha-tdma-protocol-for-beta-distributed-massive-mtc-access
#18
Nannan Sui, Youyun Xu, Cong Wang, Wei Xie
Simultaneous random access of massive machine type communications (MTC) devices are expected to cause congestion in the radio access network. Not only the performance of MTC, but the coexisting human to human (H2H) communications would also degrade dramatically without an appropriate medium access control (MAC) protocol. However, most existing solutions focus on the random access procedure without dealing with the sunsequent data transmission procedure. In this paper, we firstly derive a packet size threshold based on the capacity analysis of slotted ALOHA (S-ALOHA) and time division multiple access (TDMA) protocols...
December 15, 2017: Sensors
https://www.readbyqxmd.com/read/29244665/osseous-myopericytoma-simulating-a-giant-cell-tumor-of-bone-a-case-report
#19
Eric Bellinger, Ivy John, Daniel Zaccarini, Timothy A Damron
CASE: Myopericytoma is a benign perivascular myoid neoplasm that typically presents in the dermal and subcutaneous soft tissues of the distal aspect of the extremities. These types of tumor form a clinicopathological spectrum with myofibromas, angiopericytomas, angioleiomyomas, and glomus tumors. Intraosseous myopericytomas are exceptionally rare, and to our knowledge, no cases of myopericytoma involving long bones previously have been described. We present a case of myopericytoma occurring in the distal aspect of the femur of a 36-year-old man...
April 2017: JBJS Case Connector
https://www.readbyqxmd.com/read/29244518/differential-wavevector-distribution-of-surface-enhanced-raman-scattering-and-fluorescence-in-a-film-coupled-plasmonic-nanowire-cavity
#20
Adarsh Vasista, Harshvardhan Jog, Tal Heilpern, Matthew E Sykes, Sunny Tiwari, Deepak Kumar Sharma, Shailendra Kumar Chaubey, Gary P Wiederrecht, Stephen K Gray, G V Pavan Kumar
We report on the experimental observation of differential wavevector distribution of surface enhanced Raman scattering (SERS) and fluorescence from dye molecules confined to a gap between plasmonic silver nanowire and a thin, gold mirror. The fluorescence was mainly confined to higher values of in-plane wavevectors, whereas SERS signal was uniformly distributed along all the wavevectors. The optical energy-momentum spectra from the distal end of the nanowire revealed strong polarisation dependence of this differentiation...
December 15, 2017: Nano Letters
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