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Gynaecological oncology imaging

Vicky Koh, Bok Ai Choo, Khai Mun Lee, Teng Hwee Tan, Jen Hui Jeffrey Low, Soon Yau Joseph Ng, Arunachalam Ilancheran, Liang Shen, Johann Tang
PURPOSE: To report late rectal and bladder toxicity outcomes of a CT-based image-guided brachytherapy (IGBT) technique for treatment of cervical cancer. METHODS AND MATERIALS: Between 2008 and 2014, 95 women with International Federation of Gynecology and Obstetrics stage IB to IVA cervical carcinoma treated with definitive concurrent cisplatin-based chemotherapy and external beam radiation therapy 50.4 Gy in 28 fractions followed by planned prescription dose of 7 Gy × 4 fractions of high-dose-rate IGBT was retrospectively reviewed...
January 2017: Brachytherapy
Thomas Vinotha, Thomas Anitha, Sebastian Ajit, Chandy Rachel, Peedicayil Abraham
INTRODUCTION: Patients referred with inadequately staged ovarian malignancies present a clinical dilemma. We report our experience with completion surgery in ovarian cancer. AIMS AND OBJECTIVES: To determine the benefits and risks of completion surgery in women with ovarian cancer who presented after having had inadequate primary surgery. METHODS: A retrospective case series of 30 women with ovarian cancer and one with fallopian tube cancer who had inadequate primary surgery underwent completion surgery at gynaecologic oncology unit in a tertiary level hospital in Tamil Nadu, India...
October 2016: Journal of Obstetrics and Gynaecology of India
Roberto Angioli, Francesco Plotti, Stella Capriglione, Giuseppe Scaletta, Nella Dugo, Alessia Aloisi, Claudia Lucia Piccolo, Riccardo Del Vescovo, Corrado Terranova, Bruno Beomonte Zobel
OBJECTIVE: The aim of this study is to prospectively evaluate and compare the accuracy of high-frequency TVS and of two type of MRI (dynamic contrast-enhanced MRI or diffusion-weighted MRI), in association with HE4 in preoperative endometrial cancer (EC) staging. STUDY DESIGN: Starting from January 2012 to February 2015, all patients with EC at prior endometrial biopsy, referred to the Division of Gynaecologic Oncology of the University Campus Bio-Medico of Rome, were prospectively included in the study...
November 2016: Archives of Gynecology and Obstetrics
Anju Sahdev
CT of the abdomen and pelvis is the first line imaging modality for staging, selecting treatment options and assessing disease response in ovarian cancer. The staging CT provides disease distribution, disease burden and is the imaging surrogate for surgico-pathological FIGO staging. Optimal cyto-reductive surgery offers patients' the best chance for disease control or cure, but sub-optimal resection confers no advantage over chemotherapy and adversely increases the risk of post surgical complications. Although there is extensive literature comparing performance of CT against laparoscopy and surgery, for the staging abdominal and pelvic CT, there are currently no accepted guidelines for interpretation or routinely used minimum data set templates for reporting these complex CT scans often with extensive radiological findings...
August 2, 2016: Cancer Imaging: the Official Publication of the International Cancer Imaging Society
Rachel Kupets, K Christopher Giede, Patti Power, Anita Agrawal
OBJECTIVE: To provide guidance for referring physicians regarding what gynaecologic oncologists want and do not require in the referral package for a new patient. METHODS: An email survey was circulated to all members of the Society of Gynecologic Oncology of Canada (GOC) asking what they felt was required in a new patient referral package so that they could provide a timely consultation and management plan. RESULTS: The survey had a 79% response rate among 121 GOC members...
February 2016: Journal of Obstetrics and Gynaecology Canada: JOGC, Journal D'obstétrique et Gynécologie du Canada: JOGC
Dinesh Manoharan, Chandan J Das, Ankita Aggarwal, Arun K Gupta
The management of gynaecological malignancies has undergone a significant change in recent years with our improved understanding of cancer biogenetics, development of new treatment regimens and enhanced screening. Due to the rapid blooming of newer methods and techniques in gynaecology, surgery and oncology the scope and the role of imaging has also widened. Functional imaging in the form of diffusion weighted imaging (DWI) has been recently found to be very useful in assessing various tumours. Its ability to identify changes in the molecular level has dramatically changed the diagnostic approach of radiologists which was solely based on morphological criteria...
March 28, 2016: World Journal of Radiology
P Georgeena, Anupama Rajanbabu, D K Vijaykumar, K Pavithran, K R Sundaram, K S Deepak, M R Sanal
OBJECTIVE: To evaluate the treatment and survival pattern of patients with advanced epithelial ovarian cancer. METHODS AND RESULTS: Retrospective study of all advanced epithelial ovarian cancer patients treated in the department of gynaecologic oncology from an academic centre, in a four year period from 1 January 2008-31 December 2011. SELECTION CRITERIA: All patients with advanced epithelial ovarian cancer (stage III and IV) who underwent surgery from 2008-2011and had a follow-up of at least three months after completion of treatment were included...
2016: Ecancermedicalscience
Yulia Lakhman, Melvin D'Anastasi, Maura Miccò, Chiara Scelzo, Hebert Alberto Vargas, Stephanie Nougaret, Ramon E Sosa, Dennis S Chi, Nadeem R Abu-Rustum, Hedvig Hricak, Evis Sala
PURPOSE: To determine if second-opinion review of gynaecologic oncologic (GynOnc) magnetic resonance imaging (MRI) by sub-specialized radiologists impacts patient care. METHODS: 469 second-opinion MRI interpretations rendered by GynOnc radiologists were retrospectively compared to the initial outside reports. Two gynaecologic surgeons, blinded to the reports' origins, reviewed all cases with discrepancies between initial and second-opinion MRI reports and recorded whether these discrepancies would have led to a change in patient management defined as a change in treatment approach, counselling, or referral...
July 2016: European Radiology
P Peng, Z H Zhu, Z J Zhong, K Zheng, J X Yang, D Y Cao, K Shen
OBJECTIVE: To investigate the benefits of fluorine-18 fludeoxyglucose positron emission tomography ((18)F-FDG-PET) in patients undergoing secondary cytoreductive surgery (SCRS) for recurrent epithelial ovarian cancer. METHODS: Patients were identified, and their clinical information was extracted by review of the gynaecologic oncology database of Peking Union Medical College Hospital. (18)F-FDG-PET scan and analysis were performed by nuclear medicine experts at our hospital...
August 2015: British Journal of Radiology
Sukhbir S Singh, Stephanie Scott, Olga Bougie, Nicholas Leyland, Nicholas Leyland, Wendy Wolfman, Catherine Allaire, Alaa Awadalla, Annette Bullen, Margaret Burnett, Susan Goldstein, Madeleine Lemyre, Violaine Marcoux, Frank Potestio, David Rittenberg, Sukhbir S Singh, Grace Yeung, Paul Hoskins, Dianne Miller, Walter Gotlieb, Marcus Bernardini, Laura Hopkins
OBJECTIVE: To review the use of tissue morcellation in minimally invasive gynaecological surgery. OUTCOMES: Morcellation may be used in gynaecological surgery to allow removal of large uterine specimens, providing women with a minimally invasive surgical option. Adverse oncologic outcomes of tissue morcellation should be mitigated through improved patient selection, preoperative investigations, and novel techniques that minimize tissue dispersion. EVIDENCE: Published literature was retrieved through searches of PubMed and Medline in the spring of 2014 using appropriate controlled vocabulary (leiomyomsarcoma, uterine neoplasm, uterine myomectomy, hysterectomy) and key words (leiomyoma, endometrial cancer, uterine sarcoma, leiomyosarcoma, morcellation, and MRI)...
January 2015: Journal of Obstetrics and Gynaecology Canada: JOGC, Journal D'obstétrique et Gynécologie du Canada: JOGC
Sabrina Boyrie, Claire Charra-Brunaud, Valentin Harter, Anne Ducassou, Youlia Kirova, Isabelle Barillot, Claude Krzisch, Philippe Lang, Marie-Hélène Baron, Xavier Montbarbon, Martine Delannes, Didier Peiffert
PURPOSE: To investigate the impact of dose-volume histograms parameters on local control of three-dimensional (3D) image-based pulsed dose-rate brachytherapy (BT). METHODS AND MATERIALS: Within a French multicentric prospective study, the data of the 110 patients treated for cervical cancer with external beam radiotherapy followed by 3D image-based and optimized pulsed dose-rate BT were analyzed. Delineation procedures were performed on magnetic resonance imaging in a minority of cases and on CT for the majority of cases, adapted from the Gynaecological Groupe Européen de Curiethérapie-European Society for Therapeutic Radiology and Oncology recommendations...
July 2014: Brachytherapy
Rohit Aiyer, Kieran Sweetman, Peter Larsen-Disney, Andrew Fish
This is a case report of a 33-year-old woman who presented 5 days post-partum with abdominal distension, abdominal discomfort, increased bladder pressure and fatigue. These symptoms prompted a pelvic ultrasound and CT scan of the chest, abdomen and pelvis which showed a large 20 cm left-sided adnexal mass. Following this imaging, blood tests revealed elevated tumour markers CA-125 and lactate dehydrogenase, resulting in referral to and surgical intervention by the gynaecology oncology team. Pathology and immunohistochemistry indicated that the tumour was a metastasis from the colon, that prompted for colonoscopy which confirmed that the carcinoma was a metastases from the sigmoid...
2013: BMJ Case Reports
H He, P Bhosale, W Wei, P Ramalingam, R Iyer
AIM: To evaluate utility of magnetic resonance imaging (MRI) in determining the primary site of endometrial versus cervical tumours when the biopsy results are inconclusive. MATERIAL AND METHODS: Forty-eight patients who underwent a total hysterectomy for unknown primary adenocarcinoma of the uterus after endometrial and/or endocervical biopsies were included in the study. The 48 available pelvic MRI images were reviewed by two body radiologists independently and jointly to resolve discordance, blinded to any clinical and pathological information...
November 2013: Clinical Radiology
Emma Elliot
Endometrial cancer is the commonest gynaecological cancer in the UK. Affected women often live with long-term complex and debilitating side-effects of radiotherapy treatment, such as bowel toxicity, fatigue and psychosexual problems. Women also experience negative feelings around self-image and sexuality, which contribute to a decline in their quality of life. A review of the literature and national policy showed that women had unmet needs after completing radiotherapy treatment for endometrial cancers, and that cancer nurse specialists are in a prime position to deliver a holistic package of personalized care...
May 23, 2013: British Journal of Nursing: BJN
Barbara Segedin, Jasenka Gugic, Primoz Petric
BACKGROUND: Accurate applicator placement is a precondition for the success of gynaecological brachytherapy (BT). Unrecognized uterine perforation can lead to bleeding, infection, high doses to pelvic organs and underdosage of the target volume, resulting in acute morbidity, long-term complications and reduced chance of cure. We aimed to assess the incidence and clinical characteristics of our cases with uterine perforation, review their management and impact on the treatment course. PATINETS AND METHODS: In all patients, treated with utero-vaginal image guided BT for gynaecological cancer between January 2006 and December 2011, the CT/MR images with the applicator in place were reviewed...
June 2013: Radiology and Oncology
Ranjit Manchanda, Michael J Halaska, Jurgen M Piek, Jacek P Grabowski, Dimitrios Haidopoulos, Ignacio Zapardiel, Murat Gultekin, Boris Vranes, Kastriot Dallaku, Michaela Bossart
OBJECTIVE: The objective of this study was to highlight the relative preference of European gynecologic oncology trainees for workshops that could support and supplement their training needs. METHODS: A Web-based survey was sent to 900 trainees on the European Network of Young Gynaecological Oncologists database in November 2011. Respondents were asked to rate a 13-item questionnaire (using a 1- to 5-point Likert scale) on workshop topics they felt would most benefit their training requirements...
July 2013: International Journal of Gynecological Cancer
Shailesh Puntambekar, Geetanjali Agarwal, Saurabh N Joshi, Neeraj V Rayate, Seema S Puntambekar, Ravindra M Sathe
Minimal access surgery is an accepted modality for benign surgery. Despite the advantages of laparoscopy, its acceptance in oncology is slow. Robotic surgery is an emerging field with rapid acceptance because of the 3-dimensional image, dexterity of instruments and autonomy of camera control. We report here our experience of using the Da Vinci robot for various oncological procedures. We performed 164 oncological surgeries from November 2009 to June 2011. The surgeries performed included thoracic, colorectal, hepatobiliary, gynaecological and urological system...
June 2012: Indian Journal of Surgical Oncology
Rachel Kupets, Kimberly Fernandes, Gennady Miroshnichenko, Lawrence Paszat
OBJECTIVE: To evaluate the patterns of radiologic imaging requested by family physicians and gynaecologists in the work-up of women found to have an adnexal mass on pelvic ultrasound, and to evaluate whether advanced imaging tests are associated with more appropriate referral of women with a high-risk adnexal mass to gynaecologic oncologists. METHODS: Centralized provincial databases of health care usage were used to identify women aged 45 and older who had a pelvic ultrasound examination between 2006 and 2008...
March 2013: Journal of Obstetrics and Gynaecology Canada: JOGC, Journal D'obstétrique et Gynécologie du Canada: JOGC
Abhirami Hallock, Glenn Bauman, Nancy Read, David D'Souza, Francisco Perera, Inge Aivas, Lara Best, Jeffrey Cao, Alexander V Louie, Ericka Wiebe, Tracy Sexton, Stewart Gaede, Jerry Battista, George Rodrigues
INTRODUCTION: The objective of this study was to develop and assess the feasibility of utilizing consensus-based penalty metrics for the purpose of critical structure and organ at risk (OAR) contouring quality assurance and improvement. METHODS: A Delphi study was conducted to obtain consensus on contouring penalty metrics to assess trainee-generated OAR contours. Voxel-based penalty metric equations were used to score regions of discordance between trainee and expert contour sets...
December 2012: Journal of Medical Imaging and Radiation Oncology
Christophe Van de Wiele, Vibeke Kruse, Peter Smeets, Mike Sathekge, Alex Maes
Data available in patients suffering from squamous cell carcinoma of the head and neck, lung carcinoma, oesophageal carcinoma and gynaecological malignancies suggest that metabolic tumour volume and to a lesser extent total lesion glycolysis have the potential to become valuable in the imaging of human solid tumours as prognostic biomarkers for short- to intermediate-term survival outcomes, adding value to clinical staging, for assessment of response to treatment with neoadjuvant and concurrent chemotherapy, and for treatment optimization; for example, based on early treatment response assessment using changes in metabolic tumour volume over time, it might be possible to select patients who require a more aggressive treatment to improve their outcome...
January 2013: European Journal of Nuclear Medicine and Molecular Imaging
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