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Reproductive Imaging

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https://www.readbyqxmd.com/read/27899313/prognostic-factors-for-assisted-reproductive-technology-in-women-with-endometriosis-related-infertility
#1
Chloé Maignien, Pietro Santulli, Vanessa Gayet, Marie-Christine Lafay-Pillet, Diane Korb, Mathilde Bourdon, Louis Marcellin, Dominique de Ziegler, Charles Chapron
BACKGROUND: Assisted reproductive technology is one of the therapeutic options offered for managing endometriosis-associated infertility. Yet, published data on assisted reproductive technology outcome in women affected by endometriosis are conflicting and the determinant factors for pregnancy chances unclear. OBJECTIVE: To evaluate assisted reproductive technology outcomes in a series of 359 endometriosis patients, to identify prognostic factors and determine if there is an impact of the endometriosis phenotype...
November 26, 2016: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/27887713/magnetic-resonance-imaging-correlation-to-intraoperative-findings%C3%A2-of-deeply-infiltrative-endometriosis
#2
Traci E Ito, Elias D Abi Khalil, Myles Taffel, Gaby N Moawad
OBJECTIVE: To show characteristics of deeply infiltrative endometriosis (DIE) on magnetic resonance imaging (MRI) and how they correlate with intraoperative findings. DESIGN: Overview of still and dynamic MRI images of four different patients with DIE. We then used videos from their surgeries to highlight the appearance of endometriosis corresponding to these images (educational video). SETTING: University hospital. PATIENT(S): Four different patients with DIE were included in this video...
November 22, 2016: Fertility and Sterility
https://www.readbyqxmd.com/read/27879489/breast-fibroadenoma-with-increased-activity-on-68ga-dotatate-pet-ct
#3
Georgios Z Papadakis, Corina Millo, Samira M Sadowski, Apostolos H Karantanas, Ulas Bagci, Nicholas J Patronas
Fibroadenoma is the most common benign breast tumor in women of reproductive age, carrying little to no risk of breast cancer development. We report on a case of a woman with history of neuroendocrine tumor who on follow-up imaging tests underwent whole-body PET/CT study using Ga DOTATATE. The scan showed increased focal activity in the right breast, which was biopsied revealing a fibroadenoma. The presented data suggests cell surface overexpression of somatostatin receptors by this benign breast tumor. Moreover, this finding emphasizes the need for cautious interpretation of Ga DOTATATE-avid breast lesions that could mimic malignancy in neuroendocrine tumor patients...
November 22, 2016: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/27878600/narrow-band-imaging-for-early-diagnosis-of-epithelial-dysplasia-and-microinvasive-tumors-in-the-upper-aerodigestive-tract
#4
C Arens, C Betz, M Kraft, S Voigt-Zimmermann
The various stages of tumor growth are characterized by typical epithelial, vascular, and secondary connective tissue changes. Narrow Band Imaging (NBI) endoscopy is a minimally invasive imaging technique that presents vascular structures in particular at a higher contrast than white light endoscopy alone. In combination with high-resolution image recording and reproduction (high-definition television, HDTV; ultra-high definition, 4K), progress has been made in otolaryngological differential diagnostics, both pre- and intraoperatively...
November 23, 2016: HNO
https://www.readbyqxmd.com/read/27875946/the-role-of-sexual-dysfunction-and-infertility-on-reproductive-health-in-diabetics-pathogenesis-evaluation-and-management
#5
Jason Gandhi, Gautam Dagur, Kelly Warren, Noel Smith, Sardar Ali Khan
BACKGROUND: Uncontrolled or long-term diabetes mellitus is conducive to vascular and oxidative stress disturbances that impede several physiological systems, which may in turn elicit psychological symptoms. OBJECTIVE: We assess the sexual and hormonal complications of diabetes mellitus that impair reproductive function in males and females. METHOD: A comprehensive MEDLINE® search was guided using key words relevant to diabetes mellitus and reproductive health...
November 22, 2016: Current Diabetes Reviews
https://www.readbyqxmd.com/read/27868326/qtl-mapping-reveals-complex-genetic-architecture-of-quantitative-virulence-in-the-wheat-pathogen-zymoseptoria-tritici
#6
Ethan L Stewart, Daniel Croll, Mark H Lendenmann, Andrea Sanchez-Vallet, Fanny E Hartmann, Javier Palma-Guerrero, Xin Ma, Bruce A McDonald
We conducted a comprehensive analysis of virulence in the fungal wheat pathogen Zymoseptoria tritici using QTL mapping. High throughput phenotyping based on automated image analysis allowed measurement of pathogen virulence on a scale and with a precision that was not previously possible. Across two mapping populations encompassing more than 520 progeny, 540,710 pycnidia were counted and their sizes and grey values were measured. A significant correlation was found between pycnidia size and both spore size and number...
November 21, 2016: Molecular Plant Pathology
https://www.readbyqxmd.com/read/27862010/extension-of-research-data-repository-system-to-support-direct-compute-access-to-biomedical-datasets-enhancing-dataverse-to-support-large-datasets
#7
Bill McKinney, Peter A Meyer, Mercè Crosas, Piotr Sliz
Access to experimental X-ray diffraction image data is important for validation and reproduction of macromolecular models and indispensable for the development of structural biology processing methods. In response to the evolving needs of the structural biology community, we recently established a diffraction data publication system, the Structural Biology Data Grid (SBDG, data.sbgrid.org), to preserve primary experimental datasets supporting scientific publications. All datasets published through the SBDG are freely available to the research community under a public domain dedication license, with metadata compliant with the DataCite Schema (schema...
November 10, 2016: Annals of the New York Academy of Sciences
https://www.readbyqxmd.com/read/27842925/a-rare-case-of-right-lower-quadrant-abdominal-pain
#8
Mark Macedo, Brian Kim, Rami Khoury, Larry Narkiewicz
Isolated fallopian tube torsion without involvement of the ovary is a rare condition most frequently presenting during reproductive years. Imaging, vitals, physical exam, and laboratory findings all fail to help establish a definitive diagnosis. The majority of the diagnoses are made on the operating table. Physical exam most often reveals unilateral and localized abdominal pain, often with nausea and vomiting, but few other reliably common findings. Diagnosis becomes even more challenging due to the fact that isolated tubal torsion occurs often in pregnancy and preferentially on the right, further complicating the clinical picture...
November 3, 2016: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/27837126/medical-imaging-and-infertility
#9
Rebecca Peterson
Infertility affects many couples, and medical imaging plays a vital role in its diagnosis and treatment. Radiologic technologists benefit from having a broad understanding of infertility risk factors and causes. This article describes the typical structure and function of the male and female reproductive systems, as well as congenital and acquired conditions that could lead to a couple's inability to conceive. Medical imaging procedures performed for infertility diagnosis are discussed, as well as common interventional options available to patients...
November 2016: Radiologic Technology
https://www.readbyqxmd.com/read/27836285/practical-aspects-of-the-two-figo-systems-for-management-of-abnormal-uterine-bleeding-in-the-reproductive-years
#10
REVIEW
Malcolm G Munro
The FIGO systems defining the nomenclature and symptoms of abnormal uterine bleeding (AUB) in the reproductive years (System 1) and the PALM-COEIN classification of causes of AUB (System 2) are designed to facilitate research, education, and the provision of optimum clinical care for affected women. Development of these systems has been the result of a collaborative effort of experts in bench and translational and clinical research from six continents aided by a spectrum of representatives from relevant medical societies, journals, and regulatory bodies...
October 1, 2016: Best Practice & Research. Clinical Obstetrics & Gynaecology
https://www.readbyqxmd.com/read/27832323/deep-pelvic-endometriosis-a-radiologist-s-guide-to-key-imaging-features-with-clinical-and-histopathologic-review
#11
REVIEW
Ayeh Darvishzadeh, Wendaline McEachern, Thomas K Lee, Priya Bhosale, Ali Shirkhoda, Christine Menias, Chandana Lall
While endometriosis typically affects the ovaries, deep infiltrating endometriosis can affect the gastrointestinal tract, urinary tract, and deep pelvis, awareness of which is important for radiologists. Symptoms are nonspecific and can range from chronic abdominal and deep pelvic pain to nausea, vomiting, diarrhea, constipation, hematuria, and rectal bleeding. Ultrasound and computed tomography may show nonspecific soft-tissue density masses causing bowel obstruction and hydronephrosis. This constellation of presenting symptoms and imaging evidence is easily mistaken for other pathologies including infectious gastroenteritis, diverticulitis, appendicitis, and malignancy, which may lead to unnecessary surgery or mismanagement...
November 10, 2016: Abdominal Radiology
https://www.readbyqxmd.com/read/27826218/instrumental-tactile-diagnostics-in-robot-assisted-surgery
#12
Rozalia F Solodova, Vladimir V Galatenko, Eldar R Nakashidze, Igor L Andreytsev, Alexey V Galatenko, Dmitriy K Senchik, Vladimir M Staroverov, Vladimir E Podolskii, Mikhail E Sokolov, Victor A Sadovnichy
BACKGROUND: Robotic surgery has gained wide acceptance due to minimizing trauma in patients. However, the lack of tactile feedback is an essential limiting factor for the further expansion. In robotic surgery, feedback related to touch is currently kinesthetic, and it is mainly aimed at the minimization of force applied to tissues and organs. Design and implementation of diagnostic tactile feedback is still an open problem. We hypothesized that a sufficient tactile feedback in robot-assisted surgery can be provided by utilization of Medical Tactile Endosurgical Complex (MTEC), which is a novel specialized tool that is already commercially available in the Russian Federation...
2016: Medical Devices: Evidence and Research
https://www.readbyqxmd.com/read/27825706/avulsion-fracture-of-the-supinator-crest-as-an-indication-for-a-sustained-posterolateral-sub-luxation-of-the-elbow-a-case-report-anatomical-evaluation-and-review-of-the-literature
#13
D Broekhuis, J H J M Bessems, J W Colaris
The treatment of elbow injuries can be challenging because of the complexity of both anatomy and pathology. We present a rare traumatic avulsion fracture of the supinator crest of the ulna in a 37-year-old patient. Conservative treatment in a long arm cast for four weeks led to satisfactory results. Reproduction of the fracture on a cadaveric elbow clarified that the avulsed fragment holds the insertion of the lateral ulnar collateral ligament (LUCL). The mechanism of trauma that causes this fracture is a posterolateral (sub) luxation of the elbow, which usually causes the LUCL to rupture, but in rare cases the insertion of this ligament can be avulsed...
December 2016: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/27821650/unexpected-findings-during-evaluation-of-acute-pelvic-pain-with-transvaginal-sonography
#14
Daniel J Ohngemach, Yonah B Esterson, Naeem Rahman, Ali Noor, John S Pellerito
Transvaginal sonography is the first-line imaging modality used to evaluate acute female pelvic pain in the emergency setting because of its accessibility, lack of ionizing radiation, and excellent ability to identify reproductive tract disorders. Although the intent of transvaginal sonography is to evaluate the reproductive organs, imaging of adjacent pelvic structures is an important part of every transvaginal sonographic examination. Gastrointestinal, urologic, and vascular disorders incidentally scanned on transvaginal sonography may explain the pain for which the examination is being performed...
November 7, 2016: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/27810281/adenomyosis-and-abnormal-uterine-bleeding-aub-a-pathogenesis-diagnosis-and-management
#15
REVIEW
Jason A Abbott
The complex pathogenesis and variable presentation of adenomyosis make it one of the most difficult of the FIGO PALM-COIEN abnormal uterine bleeding group to diagnose and treat. Basic clinical parameters such as prevalence are difficult to accurately assess because histological confirmation is usually employed; however, because of the access to and accuracy and utilization of transvaginal ultrasound and other advanced imaging techniques such as MRI, noninvasive diagnosis is recognized to be highly accurate...
September 30, 2016: Best Practice & Research. Clinical Obstetrics & Gynaecology
https://www.readbyqxmd.com/read/27807892/matrix-assisted-laser-desorption-ionization-imaging-mass-spectrometry-for-the-spatial-location-of-feline-oviductal-proteins
#16
M Apparicio, V G Santos, Dfo Rocha, C R Ferreira, B I Macente, G M Magalhães, A E Alves, T F Motheo, L C Padilha-Nakaghi, E A Pires-Buttler, G C Luvoni, M N Eberlin, Wrr Vicente
With the purpose of identifying factors involved in early stages of embryo development in the domestic cat, matrix-assisted laser desorption/ionization imaging mass spectrometry (MALDI-IMS) was used for the first time to describe the spatial localization of proteins in the oviducts of queens. Oviducts were obtained from two 2 and 4 years old cross-bred queens, divided into three segments, snap-frozen in liquid nitrogen and then stored at -80°C until use. Next, they were sectioned in a cryostat, fixed on ITO (indium tin oxide) conductive glass slides for MALDI-IMS and serial sections were collected on microscope slides for histology...
November 3, 2016: Reproduction in Domestic Animals, Zuchthygiene
https://www.readbyqxmd.com/read/27803058/development-of-the-neurons-controlling-fertility-in-humans-new-insights-from-3d-imaging-and-transparent-fetal-brains
#17
Filippo Casoni, Samuel A Malone, Morgane Belle, Federico Luzzati, Francis Collier, Cecile Allet, Erik Hrabovszky, Sowmyalakshmi Rasika, Vincent Prevot, Alain Chédotal, Paolo Giacobini
Fertility in mammals is controlled by hypothalamic neurons that secrete gonadotropin-releasing hormone (GnRH). These neurons differentiate in the olfactory placodes during embryogenesis and migrate from the nose to the hypothalamus before birth. Information regarding this process in humans is sparse. Here, we adapted new tissue-clearing and whole-mount immunohistochemical techniques to entire human embryos/fetuses to meticulously study this system during the first trimester of gestation in the largest series of human fetuses examined to date...
November 1, 2016: Development
https://www.readbyqxmd.com/read/27797265/does-human-epididymis-protein-4-he4-have-a-role-in-prediction-of-recurrent-epithelial-ovarian-cancer
#18
Pedrada Innao, Methasinee Pothisuwan, Prasit Pengsa
BACKGROUND: Despite the fact that ovarian cancer is the seventh most common cancer in women worldwide and the fth leading cause of cancer death, It is the most common cause of death due to reproductive cancers in Thailand where epithelial ovarian cancer (EOC) is commonly found. According to a Thai statistical analysis in 2010 by the Department of Medical Services, epithelial ovarian cancer was the sixth most common cancer in Thailand from 2001 to 2003.The incidence of 5.1 per 100,000 women per year...
2016: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/27796017/-molecular-diagnosis-of-adpkd
#19
Francesco Scolari, Gianfranco Savoldi, Cinzia Mazza, Claudia Izzi
Most patients with ADPKD do not need molecular genetic testing. When indicated, Sanger sequencing is the most commonly used technique. When a pathogenic mutation is not identified by Sanger, multiplex ligation-dependent probe amplification analysis (MLPA) should be performed to detect gene rearrangement (insertion or deletion). The next generation sequencing (NGS) techniques can provide high-throughput and comprehensive diagnostic screening at lower cost. Finally, in the future, targeted (TS) or whole exome sequencing (WES) will likely play a role in the molecular diagnostics of ADPKD...
September 2016: Giornale Italiano di Nefrologia: Organo Ufficiale Della Società Italiana di Nefrologia
https://www.readbyqxmd.com/read/27795847/cleavage-of-human-embryos-options-and-diversity
#20
Yu K Doronin, I V Senechkin, L V Hilkevich, M A Kurcer
In order to estimate the diversity of embryo cleavage relatives to embryo progress (blastocyst formation), time-lapse imaging data of preimplantation human embryo development were used. This retrospective study is focused on the topographic features and time parameters of the cleavages, with particular emphasis on the lengths of cleavage cycles and the genealogy of blastomeres in 2- to 8-cell human embryos. We have found that all 4-cell human embryos have four developmental variants that are based on the sequence of appearance and orientation of cleavage planes during embryo cleavage from 2 to 4 blastomeres...
July 2016: Acta Naturae
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