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https://www.readbyqxmd.com/read/29692085/-application-of-non-invasive-microelectrode-ion-flux-estimation-technique-in-crop-stress-physiology
#1
Ke Liu, Bing Lin Zhang, Wen Ying Zhang, Yun Bo Zhang, Xiao Hai Tian
Non-invasive microsensing technique has been widely used in evaluating the adaptive responses of plant cells and tissues to abiotic stresses. One of the representative techniques is the microelectrode ion flux estimation (MIFE), which allows concurrent quantification of net fluxes with high spatial and temporal resolution. More importantly, this technique permits simultaneous recording of ion concentration and mobility with less intervention to the in situ physiological status. With the availability of such advanced technique, the last three decades have seen a significant progress towards the role of ion signaling in a variety of abiotic stresses including salinity, extreme temperature, osmotic stress, hypoxia, and drought...
February 2018: Ying Yong Sheng Tai Xue Bao, the Journal of Applied Ecology
https://www.readbyqxmd.com/read/29691913/thiazoloisoindigo-a-building-block-that-merges-the-merits-of-thienoisoindigo-and-diazaisoindigo-for-conjugated-polymers
#2
Xiaobo Wan, Chenchen Li, Xiao Wang, Un Hio-Ieng, Jiawei Peng, Zhenggang Lan, Mian Cai, Jian Pei, Jieyu Wang
Thiazoloisoindigo, a novel structural variation of isoindigo, is for the first time utilized to synthesize conjugated polymers. Polymer based on thiazoloisoindigo merges the advantages of the one based on thienoisoindigo and diazaisoindigo: It not only exhibits a greatly red shifted UV-vis absorption to the near-infrared region due to its strong tendency to form quinoidal structures, similar to that based on thienoisoindigo, but also shows excellent ambipolar mobility (hole 3.93 and electron 1.07 cm2 V-1 s-1, respectively) in organic field-effect transistors (OFETs), superior than that based on diazaisoindigo, showing the strong electron-withdrawing capability of thiazoloisoindigo...
April 24, 2018: Chemistry: a European Journal
https://www.readbyqxmd.com/read/29691840/cost-effectiveness-of-population-based-vascular-disease-screening-and-intervention-in-men-from-the-viborg-vascular-viva-trial
#3
R Søgaard, J S Lindholt
BACKGROUND: Population-based screening and intervention for abdominal aortic aneurysm, peripheral artery disease and hypertension was recently reported to reduce the relative risk of mortality among Danish men by 7 per cent. The aim of this study was to investigate the cost-effectiveness of vascular screening versus usual care (ad hoc primary care-based risk assessment) from a national health service perspective. METHODS: A cost-effectiveness evaluation was conducted alongside an RCT involving all men from a region in Denmark (50 156) who were allocated to screening (25 078) or no screening (25 078) and followed for up to 5 years...
April 25, 2018: British Journal of Surgery
https://www.readbyqxmd.com/read/29691788/tissue-identification-in-a-porcine-model-by-differential-ion-mobility-spectrometry-analysis-of-surgical-smoke
#4
Anton Kontunen, Markus Karjalainen, Jukka Lekkala, Antti Roine, Niku Oksala
Electrosurgery is widely used in various surgical operations. When tissue is cut with high-frequency current, the cell contents at the incision area evaporate and together with water and possible soot particles, form surgical smoke. The smoke contains cell metabolites, and therefore, possible biomarkers for cancer or bacterial infection. Thus, the analysis of surgical smoke could be used in intraoperative medical diagnostics. We present a method that can be used to detect the characteristics of various tissue types by means of differential ion mobility spectrometry (DMS) analysis of surgical smoke...
April 24, 2018: Annals of Biomedical Engineering
https://www.readbyqxmd.com/read/29691772/evaluation-of-quality-of-life-in-patients-with-axial-spondyloarthritis-and-its-association-with-disease-activity-functionality-mobility-and-structural-damage
#5
Clementina López-Medina, Juan L Garrido-Castro, Juan Castro-Jiménez, Cristina González-Navas, Jerusalem Calvo-Gutiérrez, M Carmen Castro-Villegas, Rafaela Ortega-Castro, Alejandro Escudero-Contreras, Pilar Font-Ugalde, Eduardo Collantes-Estévez
To evaluate quality of life (QoL) in patients with axial spondyloarthritis (axSpA) and its association with disease activity, functionality, structural damage, and spinal mobility, using patient-reported outcomes. This was an observational, cross-sectional, and single-center study in which 100 consecutive patients with axSpA were included. We obtained from all patients' sociodemographic data and values related to disease activity, functionality, structural damage, mobility, and quality of life. The Ankylosing Spondylitis Quality of Life Questionnaire (ASQoL) was considered as the primary outcome...
April 24, 2018: Clinical Rheumatology
https://www.readbyqxmd.com/read/29691730/differentiation-of-dental-restorative-materials-combining-energy-dispersive-x-ray-fluorescence-spectroscopy-and-post-mortem-ct
#6
Tim Merriam, Rolf Kaufmann, Lars Ebert, Renato Figi, Rolf Erni, Robin Pauer, Till Sieberth
Today, post-mortem computed tomography (CT) is routinely used for forensic identification. Mobile energy-dispersive X-ray fluorescence (EDXRF) spectroscopy of a dentition is a method of identification that has the potential to be easier and cheaper than CT, although it cannot be used with every dentition. In challenging cases, combining both techniques could facilitate the process of identification and prove to be advantageous over chemical analyses. Nine dental restorative material brands were analyzed using EDXRF spectroscopy...
April 24, 2018: Forensic Science, Medicine, and Pathology
https://www.readbyqxmd.com/read/29691547/long-range-single-domain-array-of-a-5-nm-pattern-of-supramolecules-via-solvent-annealing-in-a-double-sandwich-cell
#7
Kiok Kwon, Kangho Park, Hee-Tae Jung
In nanotechnology and microelectronics research, the generation of an ultradense, single-grain nanostructure with a long-range lateral order is challenging. In this paper, we report upon a new solvent-annealing method using a double-sandwich confinement to promote the formation of a large-area, single-domain array (>0.3 × 0.3 mm2) of supramolecular cylinders with a small feature size (4.7 nm). The in situ GISAXS experiment result shows the ordering process during solvent evaporation. The diffusion of the solvent molecules led to the disassembly of the supramolecules confined between the top and bottom surfaces and their subsequent mobilization, thereby producing a highly ordered hexagonal array of supramolecular materials under the double-sandwich confinement upon solvent evaporation...
April 25, 2018: Nanoscale
https://www.readbyqxmd.com/read/29691368/a-novel-sigb-q225p-mutation-in-staphylococcus-aureus-retains-virulence-but-promotes-biofilm-formation
#8
Hui Liu, Weilong Shang, Zhen Hu, Ying Zheng, Jizhen Yuan, Qiwen Hu, Huagang Peng, Xinyu Cai, Li Tan, Shu Li, Junmin Zhu, Ming Li, Xiaomei Hu, Renjie Zhou, Xiancai Rao, Yi Yang
Staphylococcus aureus is an important pathogen that produces abundant virulence factors, which cause various diseases that burden human health worldwide. The stress response regulon called sigma factor B (SigB) is a well-characterized global regulator that is involved in the regulation of S. aureus virulence, pigmentation, and biofilm formation. However, the regulatory network upon SigB in S. aureus is incompletely described. Here, we identified a novel substitution mutation, SigB(Q225P), which contributed the nonpigmented phenotype of S...
April 25, 2018: Emerging Microbes & Infections
https://www.readbyqxmd.com/read/29691340/extensive-gene-amplification-as-a-mechanism-for-piperacillin-tazobactam-resistance-in-escherichia-coli
#9
Lisa M Schechter, David P Creely, Cherilyn D Garner, Dee Shortridge, Hoan Nguyen, Lei Chen, Blake M Hanson, Erica Sodergren, George M Weinstock, W Michael Dunne, Alex van Belkum, Shana R Leopold
Although the TEM-1 β-lactamase (BlaTEM-1 ) hydrolyzes penicillins and narrow-spectrum cephalosporins, organisms expressing this enzyme are typically susceptible to β-lactam/β-lactamase inhibitor combinations such as piperacillin-tazobactam (TZP). However, our previous work led to the discovery of 28 clinical isolates of Escherichia coli resistant to TZP that contained only bla TEM-1 One of these isolates, E. coli 907355, was investigated further in this study. E. coli 907355 exhibited significantly higher β-lactamase activity and BlaTEM-1 protein levels when grown in the presence of subinhibitory concentrations of TZP...
April 24, 2018: MBio
https://www.readbyqxmd.com/read/29691332/clinically-relevant-plasmid-host-interactions-indicate-that-transcriptional-and-not-genomic-modifications-ameliorate-fitness-costs-of-klebsiella-pneumoniae-carbapenemase-carrying-plasmids
#10
Michelle M C Buckner, Howard T H Saw, Rachael N Osagie, Alan McNally, Vito Ricci, Matthew E Wand, Neil Woodford, Alasdair Ivens, Mark A Webber, Laura J V Piddock
The rapid dissemination of antimicrobial resistance (AMR) around the globe is largely due to mobile genetic elements, such as plasmids. They confer resistance to critically important drugs, including extended-spectrum beta-lactams, carbapenems, and colistin. Large, complex resistance plasmids have evolved alongside their host bacteria. However, much of the research on plasmid-host evolution has focused on small, simple laboratory plasmids in laboratory-adapted bacterial hosts. These and other studies have documented mutations in both host and plasmid genes which occur after plasmid introduction to ameliorate fitness costs of plasmid carriage...
April 24, 2018: MBio
https://www.readbyqxmd.com/read/29691216/the-usability-and-effectiveness-of-mobile-health-technology-based-lifestyle-and-medical-intervention-apps-supporting-health-care-during-pregnancy-systematic-review
#11
REVIEW
Sanne B Overdijkink, Adeline V Velu, Ageeth N Rosman, Monique Dm van Beukering, Marjolein Kok, Regine Pm Steegers-Theunissen
BACKGROUND: A growing number of mobile health (mHealth) technology-based apps are being developed for personal lifestyle and medical health care support, of which several apps are related to pregnancy. Evidence on usability and effectiveness is limited but crucial for successful implementation. OBJECTIVE: This study aimed to evaluate the usability, that is, feasibility and acceptability, as well as effectiveness of mHealth lifestyle and medical apps to support health care during pregnancy in high-income countries...
April 24, 2018: JMIR MHealth and UHealth
https://www.readbyqxmd.com/read/29691214/mobile-health-initiatives-in-vietnam-scoping-study
#12
Jeffrey A Lam, Linh Thuy Dang, Ngoc Tran Phan, Hue Thi Trinh, Nguyen Cong Vu, Cuong Kieu Nguyen
BACKGROUND: Mobile health (mHealth) offers a promising solution to the multitude of challenges the Vietnamese health system faces, but there is a scarcity of published information on mHealth in Vietnam. OBJECTIVE: The objectives of this scoping study were (1) to summarize the extent, range, and nature of mHealth initiatives in Vietnam and (2) to examine the opportunities and threats of mHealth utilization in the Vietnamese context. METHODS: This scoping study systematically identified and extracted relevant information from 20 past and current mHealth initiatives in Vietnam...
April 24, 2018: JMIR MHealth and UHealth
https://www.readbyqxmd.com/read/29691213/an-mhealth-app-for-decision-making-support-in-wound-dressing-selection-wounds-protocol-for-a-user-centered-feasibility-study
#13
Scott Jordan, Jane McSwiggan, Joanne Parker, Gayle A Halas, Marcia Friesen
BACKGROUND: Primary care health professionals, especially family physicians, see a variety of wounds, and yet-despite the frequency of providing wound care-many family physicians do not feel confident in wound care management. This is partly due to a lack of formal wound education in Family Medicine programs. While there are numerous electronic wound care resources available in the UK and North America, none were identified that address the specific need in supporting clinical decision-making in wound dressing selection...
April 24, 2018: JMIR Research Protocols
https://www.readbyqxmd.com/read/29691211/developing-a-third-party-analytics-application-using-australia-s-national-personal-health-records-system-case-study
#14
Niranjan Bidargaddi, Yasmin van Kasteren, Peter Musiat, Michael Kidd
BACKGROUND: My Health Record (MyHR) is Australia's national electronic health record (EHR) system. Poor usability and functionality have resulted in low utility, affecting enrollment and participation rates by both patients and clinicians alike. Similar to apps on mobile phone app stores, innovative third-party applications of MyHR platform data can enhance the usefulness of the platform, but there is a paucity of research into the processes involved in developing third-party applications that integrate and use data from EHR systems...
April 24, 2018: JMIR Medical Informatics
https://www.readbyqxmd.com/read/29691208/the-use-of-digital-and-remote-communication-technologies-as-a-tool-for-multiple-sclerosis-management-narrative-review
#15
Martin Marziniak, Giampaolo Brichetto, Peter Feys, Uta Meyding-Lamadé, Karen Vernon, Sven G Meuth
Despite recent advances in multiple sclerosis (MS) care, many patients only infrequently access health care services, or are unable to access them easily, for reasons such as mobility restrictions, travel costs, consultation and treatment time constraints, and a lack of locally available MS expert services. Advances in mobile communications have led to the introduction of electronic health (eHealth) technologies, which are helping to improve both access to and the quality of health care services. As the Internet is now readily accessible through smart mobile devices, most people can take advantage of eHealth apps...
April 24, 2018: JMIR Rehabilitation and Assistive Technologies
https://www.readbyqxmd.com/read/29691205/developing-sustainable-and-impactful-mobile-phone-hiv-testing-interventions-for-spanish-speaking-men-who-have-sex-with-men-in-the-united-states-lessons-learned-from-informative-interviews
#16
Jason Mitchell, Maria Beatriz Torres, Lucy Asmar, Thu Danh, Keith J Horvath
BACKGROUND: Although many men who have sex with men (MSM) test for HIV at least once in their lifetime, opportunities to improve regular HIV testing, particularly among Hispanic or Latino MSM, is needed. Many mHealth interventions in development, including the ones on HIV testing, have primarily focused on English-speaking white, black, and MSM of other races. To date, no studies have assessed app use, attitudes, and motivations for downloading and sustaining use of mobile apps and preferences with respect to HIV prevention among Spanish-speaking, Hispanic MSM in the United States...
April 24, 2018: JMIR Public Health and Surveillance
https://www.readbyqxmd.com/read/29691128/ice-parties-among-young-men-who-have-sex-with-men-in-thailand-pleasures-secrecy-and-risks
#17
Thomas E Guadamuz, Pimpawun Boonmongkon
BACKGROUND: Crystal methamphetamine (ice) has become the substance of choice among young men who have sex with men (YMSM) in urban Thailand. Yet, there is scarce data on this phenomenon, partly due to the difficulty in accessing men who will disclose and openly discuss the social contexts, meanings and risks surrounding ice practice. We present an ethnography of ice parties, critically discussing the in-depth social meanings of ice; the sexual socialities and the secrecy surrounding its use; the transactions between older and younger men; and the role of the Internet and mobile technology...
April 21, 2018: International Journal on Drug Policy
https://www.readbyqxmd.com/read/29691111/helping-patients-help-themselves-supporting-the-healthcare-journey
#18
Moriah E Ellen, Ruth Shach, Ran D Balicer
Patients often feel lost when navigating the health care system, and poor care coordination leads to negative patient outcomes, consumes resources and makes diseases more difficult to treat. Patients and citizens have become eager to take health care decision making into their own hands. To this end, solutions have been proposed which assist patients by providing them with more information and enabling them to take a more active role in their care. These include enlisting a patient navigator, consumer engagement, process mapping, decision aids, and clinical pathways...
April 14, 2018: Patient Education and Counseling
https://www.readbyqxmd.com/read/29691066/uncertainty-and-variability-in-laboratory-derived-sorption-parameters-of-sediments-from-a-uranium-in-situ-recovery-site
#19
Martin A Dangelmayr, Paul W Reimus, Raymond H Johnson, James T Clay, James J Stone
This research assesses the ability of a GC SCM to simulate uranium transport under variable geochemical conditions typically encountered at uranium in-situ recovery (ISR) sites. Sediment was taken from a monitoring well at the SRH site at depths 192 and 193 m below ground and characterized by XRD, XRF, TOC, and BET. Duplicate column studies on the different sediment depths, were flushed with synthesized restoration waters at two different alkalinities (160 mg/l CaCO3 and 360 mg/l CaCO3 ) to study the effect of alkalinity on uranium mobility...
April 18, 2018: Journal of Contaminant Hydrology
https://www.readbyqxmd.com/read/29691061/fractional-order-uncertainty-estimator-based-hierarchical-sliding-mode-design-for-a-class-of-fractional-order-non-holonomic-chained-system
#20
Deepika, Sandeep Kaur, Shiv Narayan
This paper proposes a novel fractional order sliding mode control approach to address the issues of stabilization as well as tracking of an N-dimensional extended chained form of fractional order non-holonomic system. Firstly, the hierarchical fractional order terminal sliding manifolds are selected to procure the desired objectives in finite time. Then, a sliding mode control law is formulated which provides robustness against various system uncertainties or external disturbances. In addition, a novel fractional order uncertainty estimator is deduced mathematically to estimate and mitigate the effects of uncertainties, which also excludes the requirement of their upper bounds...
April 21, 2018: ISA Transactions
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