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https://www.readbyqxmd.com/read/27916585/perinatal-exposure-to-glyphosate-based-herbicide-alters-the-thyrotrophic-axis-and-causes-thyroid-hormone-homeostasis-imbalance-in-male-rats
#1
Janaina Sena de Souza, Marina Malta Letro Kizys, Rodrigo Rodrigues da Conceição, Gabriel Glebocki, Renata Marino Romano, Tania Maria Ortiga-Carvalho, Gisele Giannocco, Ismael Dale Cotrim Guerreiro da Silva, Magnus Regios Dias da Silva, Marco Aurélio Romano, Maria Izabel Chiamolera
Glyphosate-based herbicides (GBHs) are widely used in agriculture. Recently, several animal and epidemiological studies have been conducted to understand the effects of these chemicals as an endocrine disruptor for the gonadal system. The aim of the present study was to determine whether GBHs could also disrupt the hypothalamic-pituitary-thyroid (HPT) axis. Female pregnant Wistar rats were exposed to a solution containing GBH Roundup(®)Transorb (Monsanto). The animals were divided into three groups (control, 5mg/kg/day or 50mg/kg/day) and exposed from gestation day 18 (GD18) to post-natal day 5 (PND5)...
December 1, 2016: Toxicology
https://www.readbyqxmd.com/read/27878362/a-3-d-analysis-of-the-protympanum-in-human-temporal-bones-with-chronic-ear-disease
#2
Henrique F Pauna, Rafael C Monsanto, Patricia Schachern, Michael M Paparella, Sebahattin Cureoglu
Eustachian tube dysfunction is believed to be an important factor to cholesteatoma development and recurrence of disease after surgical treatment. Although many studies have described prognostic factors, evaluation methods, or surgical techniques for Eustachian tube dysfunction, they relied on the soft tissues of its structure; little is known about its bony structure-the protympanum-which connects the Eustachian tube to the tympanic cavity, and can also be affected by several inflammatory conditions, both from the middle ear or from the nasopharynx...
November 22, 2016: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/27780247/genetic-vulnerability-and-the-relationship-of-commercial-germplasms-of-maize-in-brazil-with-the-nested-association-mapping-parents
#3
Luciano Rogério Braatz de Andrade, Roberto Fritsche Neto, Ítalo Stefanine Correia Granato, Gustavo César Sant'Ana, Pedro Patric Pinho Morais, Aluízio Borém
A few breeding companies dominate the maize (Zea mays L.) hybrid market in Brazil: Monsanto® (35%), DuPont Pioneer® (30%), Dow Agrosciences® (15%), Syngenta® (10%) and Helix Sementes (4%). Therefore, it is important to monitor the genetic diversity in commercial germplasms as breeding practices, registration and marketing of new cultivars can lead to a significant reduction of the genetic diversity. Reduced genetic variation may lead to crop vulnerabilities, food insecurity and limited genetic gains following selection...
2016: PloS One
https://www.readbyqxmd.com/read/27746846/treatment-and-prognosis-of-facial-palsy-on-ramsay-hunt-syndrome-results-based-on-a-review-of-the-literature
#4
Rafael da Costa Monsanto, Aline Gomes Bittencourt, Natal José Bobato Neto, Silvia Carolina Almeida Beilke, Fabio Tadeu Moura Lorenzetti, Raquel Salomone
Introduction Ramsay Hunt syndrome is the second most common cause of facial palsy. Early and correct treatment should be performed to avoid complications, such as permanent facial nerve dysfunction. Objective The objective of this study is to review the prognosis of the facial palsy on Ramsay Hunt syndrome, considering the different treatments proposed in the literature. Data Synthesis We read the abstract of 78 studies; we selected 31 studies and read them in full. We selected 19 studies for appraisal...
October 2016: International Archives of Otorhinolaryngology
https://www.readbyqxmd.com/read/27740937/implications-of-immune-dysfunction-on-endometriosis-associated-infertility
#5
Jessica E Miller, Soo Hyun Ahn, Stephany P Monsanto, Kasra Khalaj, Madhuri Koti, Chandrakant Tayade
Endometriosis is a complex, inflammatory disease that affects 6-10% of reproductive-aged women. Almost half of the women with endometriosis experience infertility. Despite the excessive prevalence, the pathogenesis of endometriosis and its associated infertility is unknown and a cure is not available. While many theories have been suggested to link endometriosis and infertility, a consensus among investigators has not emerged. In this extensive review of the literature as well as research from our laboratory, we provide potential insights into the role of immune dysfunction in endometriosis associated infertility...
October 11, 2016: Oncotarget
https://www.readbyqxmd.com/read/27727224/bayer-bids-66-billion-for-monsanto
#6
Emily Waltz
No abstract text is available yet for this article.
October 11, 2016: Nature Biotechnology
https://www.readbyqxmd.com/read/27677667/glyphosate-in-the-general-population-and-in-applicators-a-critical-review-of-studies-on-exposures
#7
Keith R Solomon
The recent classification of glyphosate as a probable human carcinogen by the International Agency for Research on Cancer (IARC) was arrived at without a detailed assessment of exposure. Glyphosate is widely used as an herbicide, which might result in exposures of the general public and applicators. Exposures were estimated from information in the open literature and unpublished reports provided by Monsanto Company. Based on the maximum measured concentration in air, an exposure dose of 1.04 × 10 (-) (6 )mg/kg body mass (b...
September 2016: Critical Reviews in Toxicology
https://www.readbyqxmd.com/read/27632924/the-new-total-western-diet-for-rodents-does-not-induce-an-overweight-phenotype-or-alter-parameters-of-metabolic-syndrome-in-mice
#8
Stephany P Monsanto, Korry J Hintze, Robert E Ward, Deanna P Larson, Michael Lefevre, Abby D Benninghoff
In this study, we determined the impact of the total Western diet (TWD) for rodents and its macro- and micronutrient components on weight gain and biomarkers of metabolic function in mice compared to a 45% fat diet-induced obesity (DIO) diet and the standard AIN93G diet. We hypothesized that mice fed the TWD would have increased body fat with indicators of metabolic syndrome similar to mice consuming the DIO diet. As expected, DIO-fed mice acquired a metabolic syndrome phenotype typified by increased energy intake, increased body weight gain, increased fat mass, higher fasting glucose, impaired glucose tolerance, and higher plasma leptin relative to the AIN93G diet...
September 2016: Nutrition Research
https://www.readbyqxmd.com/read/27601960/evaluating-deviations-in-prostatectomy-patients-treated-with-imrt
#9
Ana Cravo Sá, Ana Peres, Mónica Pereira, Carina Marques Coelho, Fátima Monsanto, Ana Macedo, Adrian Lamas
AIM: To evaluate the deviations in prostatectomy patients treated with IMRT in order to calculate appropriate margins to create the PTV. BACKGROUND: Defining inappropriate margins can lead to underdosing in target volumes and also overdosing in healthy tissues, increasing morbidity. MATERIAL AND METHODS: 223 CBCT images used for alignment with the CT planning scan based on bony anatomy were analyzed in 12 patients treated with IMRT following prostatectomy...
May 2016: Reports of Practical Oncology and Radiotherapy
https://www.readbyqxmd.com/read/27455393/the-surgical-challenge-of-carotid-artery-and-fallopian-canal-dehiscence-in-chronic-ear-disease-a-pitfall-for-endoscopic-approach
#10
H F Pauna, R C Monsanto, P A Schachern, S S Costa, G Kwon, M M Paparella, S Cureoglu
OBJECTIVE: Endoscopic procedures are becoming common in middle ear surgery. Inflammation due to chronic ear disease can cause bony erosion of the carotid artery and Fallopian canals, making them more vulnerable during surgery. The objective of this study was to determine whether or not chronic ear disease increases dehiscence of the carotid artery and Fallopian canals. DESIGN: Comparative human temporal bone study. SETTING: Otopathology laboratory...
July 25, 2016: Clinical Otolaryngology
https://www.readbyqxmd.com/read/27440440/a-three-dimensional-analysis-of-the-endolymph-drainage-system-in-m%C3%A3-ni%C3%A3-re-disease
#11
Rafael da Costa Monsanto, Henrique F Pauna, Geeyoun Kwon, Patricia A Schachern, Vladimir Tsuprun, Michael M Paparella, Sebahattin Cureoglu
OBJECTIVES/HYPOTHESIS: To measure the volume of the endolymph drainage system in temporal bone specimens with Ménière disease, as compared with specimens with endolymphatic hydrops without vestibular symptoms and with nondiseased specimens STUDY DESIGN: Comparative human temporal bone analysis. METHODS: We generated three-dimensional models of the vestibular aqueduct, endolymphatic sinus and duct, and intratemporal portion of the endolymphatic sac and calculated the volume of those structures...
July 21, 2016: Laryngoscope
https://www.readbyqxmd.com/read/27334821/caryospora-peneireiroi-n-sp-apicomplexa-eimeriidae-in-the-common-kestrel-falco-tinnunculus-falconiformes-falconidae-in-mainland-portugal
#12
Sergian Vianna Cardozo, Bruno Pereira Berto, Inês Caetano, Viviane Camara Maniero, Isabel Pereira da Fonseca, Carlos Wilson Gomes Lopes
The common kestrel Falco tinnunculus Linnaeus, 1758, is a widespread raptor, native in Europe, Asia and Africa, and vagrant in the Americas. In the current work, 27 fecal samples were collected from common kestrels kept in the Lisbon Center for Wild Animal Recovery, located at Monsanto Forest Park, Lisbon, Portugal. Five (19%) of them were found to be passing an undescribed species of Caryospora in their feces. The oocysts of Caryospora peneireiroi n. sp. were ellipsoidal with a bilayered wall and measured 47...
June 7, 2016: Revista Brasileira de Parasitologia Veterinária, Brazilian Journal of Veterinary Parasitology
https://www.readbyqxmd.com/read/27276668/caryospora-peneireiroi-n-sp-apicomplexa-eimeriidae-in-the-common-kestrel-falco-tinnunculus-falconiformes-falconidae-in-mainland-portugal
#13
Sergian Vianna Cardozo, Bruno Pereira Berto, Inês Caetano, Viviane Camara Maniero, Isabel Pereira da Fonseca, Carlos Wilson Gomes Lopes
The common kestrel Falco tinnunculus Linnaeus, 1758, is a widespread raptor, native in Europe, Asia and Africa, and vagrant in the Americas. In the current work, 27 fecal samples were collected from common kestrels kept in the Lisbon Center for Wild Animal Recovery, located at Monsanto Forest Park, Lisbon, Portugal. Five (19%) of them were found to be passing an undescribed species of Caryospora in their feces. The oocysts of Caryospora peneireiroi n. sp. were ellipsoidal with a bilayered wall and measured 47...
June 7, 2016: Revista Brasileira de Parasitologia Veterinária, Brazilian Journal of Veterinary Parasitology
https://www.readbyqxmd.com/read/27165677/pathologic-changes-of-the-peripheral-vestibular-system-secondary-to-chronic-otitis-media
#14
Rafael da Costa Monsanto, Mehmet Erdil, Henrique F Pauna, Geeyoun Kwon, Patricia A Schachern, Vladimir Tsuprun, Michael M Paparella, Sebahattin Cureoglu
OBJECTIVE: To evaluate the histopathologic changes of dark, transitional, and hair cells of the vestibular system in human temporal bones from patients with chronic otitis media. STUDY DESIGN: Comparative human temporal bone study. SETTING: Otopathology laboratory. SUBJECTS AND METHODS: To compare the density of vestibular dark, transitional, and hair cells in temporal bones with and without chronic otitis media, we used differential interference contrast microscopy...
September 2016: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/27107158/epitympanum-volume-and-tympanic-isthmus-area-in-temporal-bones-with-retraction-pockets
#15
Rafael da Costa Monsanto, Henrique Furlan Pauna, Serdar Kaya, Ömer Hızlı, Geeyoun Kwon, Michael M Paparella, Sebahattin Cureoglu
OBJECTIVES/HYPOTHESIS: To compare the volume of the epitympanic space, as well as the area of the tympanic isthmus, in human temporal bones with retraction pockets to those with chronic otitis media without retraction pockets and to those with neither condition. STUDY DESIGN: Comparative human temporal bone study. METHODS: We generated a three-dimensional model of the bony epitympanum and measured the epitympanic space. We also compared the area of the tympanic isthmus...
April 23, 2016: Laryngoscope
https://www.readbyqxmd.com/read/27075694/peripheral-vestibular-pathology-in-mondini-dysplasia
#16
Serdar Kaya, Ömer Hızlı, Fatıma Kübra Kaya, Rafael DaCosta Monsanto, Michael M Paparella, Sebahattin Cureoglu
OBJECTIVES/HYPOTHESIS: In this study, our objective was to histopathologically analyze the peripheral vestibular system in patients with Mondini dysplasia. STUDY DESIGN: Comparative human temporal bone study. METHODS: We assessed the sensory epithelium of the human vestibular system with a focus on the number of type I and type II hair cells, as well as the total number of hair cells. We compared those numbers in our Mondini dysplasia group versus our control group...
April 14, 2016: Laryngoscope
https://www.readbyqxmd.com/read/26901800/changes-in-rhizosphere-bacterial-gene-expression-following-glyphosate-treatment
#17
Molli M Newman, Nicola Lorenz, Nigel Hoilett, Nathan R Lee, Richard P Dick, Mark R Liles, Cliff Ramsier, Joseph W Kloepper
In commercial agriculture, populations and interactions of rhizosphere microflora are potentially affected by the use of specific agrichemicals, possibly by affecting gene expression in these organisms. To investigate this, we examined changes in bacterial gene expression within the rhizosphere of glyphosate-tolerant corn (Zea mays) and soybean (Glycine max) in response to long-term glyphosate (PowerMAX™, Monsanto Company, MO, USA) treatment. A long-term glyphosate application study was carried out using rhizoboxes under greenhouse conditions with soil previously having no history of glyphosate exposure...
May 15, 2016: Science of the Total Environment
https://www.readbyqxmd.com/read/26888903/biographical-feature-alexander-c-sonnenwirth-ph-d
#18
Andrew B Onderdonk
No abstract text is available yet for this article.
May 2016: Journal of Clinical Microbiology
https://www.readbyqxmd.com/read/26698677/surgical-removal-of-endometriotic-lesions-alters-local-and-systemic-proinflammatory-cytokines-in-endometriosis-patients
#19
Stephany P Monsanto, Andrew K Edwards, Juhua Zhou, Prakash Nagarkatti, Mitzi Nagarkatti, Steven L Young, Bruce A Lessey, Chandrakant Tayade
OBJECTIVE: To determine the impact of endometriotic lesion removal on local and systemic inflammation. DESIGN: Multiplex cytokine analysis on samples from endometriosis patients before surgery, 2 weeks after surgery, and 3 months after surgery. SETTING: Academic teaching hospital and university. PATIENT(S): A total of 43 endometriosis patients before and after excision of lesions by means of laparoscopic surgery, and 25 normal women...
April 2016: Fertility and Sterility
https://www.readbyqxmd.com/read/26573155/histopathologic-ear-findings-of-syphilis-a-temporal-bone-study
#20
Ömer Hızlı, Pelin Hızlı, Serdar Kaya, Rafael da Costa Monsanto, Michael M Paparella, Sebahattin Cureoglu
To the best of our knowledge, histopathologic studies of syphilitic ears have generally focused on hydropic changes; so far, no such studies have investigated peripheral vestibular otopathology using differential interference contrast microscopy, in patients with syphilis. For this study, we examined 13 human temporal bone samples from 8 patients with a history of syphilis. Using conventional light microscopy, we performed qualitative histopathologic assessment. In addition, using differential interference contrast microscopy, we performed type I and type II vestibular hair cell counts on each vestibular sense organ with minimal autolysis; in which the neuroepithelium was oriented perpendicular to the plane of section...
September 2016: European Archives of Oto-rhino-laryngology
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