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https://www.readbyqxmd.com/read/29699430/current-evidence-of-peripheral-vestibular-symptoms-secondary-to-otitis-media
#1
Rafael Costa Monsanto, Ana Luiza Papi Kasemodel, Andreza Tomaz, Michael M Paparella, Norma O Penido
BACKGROUND: The association between otitis media and vestibular symptoms has been hypothesized in the past. Thus, in this study, we aimed to critically analyze (based in a systematic review of the literature) whether patients who have otitis media are at greater risk of developing vestibular impairment or not. METHODS: We performed a systematic review of the literature, and identified potentially relevant articles reporting vestibular symptoms and results of vestibular function tests in patients with otitis media through searches of the PubMED, Web of Science, Scopus, and Google Scholar databases...
April 26, 2018: Annals of Medicine
https://www.readbyqxmd.com/read/29676724/wolbachia-mediated-protection-of-drosophila-melanogaster-against-systemic-infection-with-its-natural-viral-pathogen-drosophila-c-virus-does-not-involve-changes-in-levels-of-highly-abundant-mirnas
#2
Verna Monsanto-Hearne, Karyn N Johnson
The presence of Wolbachia confers virus protection to insects. The molecular mechanism underlying Wolbachia-mediated protection in this tripartite host-endosymbiont-virus interaction is not yet fully understood. In the bipartite association between Drosophila melanogaster and Drosophila C virus (DCV), changes in the expression of microRNAs (miRNAs) influence the outcome of viral pathogenesis. Here we examined whether changes in miRNA expression are similarly involved in the Drosophila-Wolbachia-DCV association...
April 20, 2018: Journal of General Virology
https://www.readbyqxmd.com/read/29570040/chemical-warfare-in-colombia-evidentiary-ecologies-and-senti-actuando-practices-of-justice
#3
Kristina Lyons
Between 1994 and 2015, militarized aerial fumigation was a central component of US-Colombia antidrug policy. Crop duster planes sprayed a concentrated formula of Monsanto's herbicide, glyphosate, over illicit crops, and also forests, soils, pastures, livestock, watersheds, subsistence food and human bodies. Given that a national peace agreement was signed in 2016 between FARC-EP guerrillas and the state to end Colombia's over five decades of war, certain government officials are quick to proclaim aerial fumigation of glyphosate an issue of the past...
March 1, 2018: Social Studies of Science
https://www.readbyqxmd.com/read/29357715/economic-burden-of-varicella-in-children-1-12-years-of-age-in-argentina-2009-2014
#4
Norberto Giglio, Homero Monsanto, Emmanouil Rampakakis, H Keri Yang, Barbara J Kuter, Lara J Wolfson
BACKGROUND: In Argentina, varicella vaccination was included in the national schedule for mandatory immunizations in 2015. The vaccine has been shown to substantially reduce the morbidity and mortality associated with the virus. The purpose of this study was to evaluate the clinical and economic burden associated with varicella in Argentina prior to vaccine introduction. METHODS: This was a multi-center, retrospective chart review study among patients aged 1-12 years with a primary varicella diagnosis in 2009-2014 in Argentina...
April 2018: Journal of Medical Economics
https://www.readbyqxmd.com/read/29190725/modelling-the-effects-of-quadrivalent-human-papillomavirus-hpv-vaccination-in-puerto-rico
#5
Ana Patricia Ortiz, Karen J Ortiz-Ortiz, Moraima Ríos, José Laborde, Amit Kulkarni, Matthew Pillsbury, Andreas Lauschke, Homero A Monsanto, Cecile Marques-Goyco
BACKGROUND: No study has estimated the potential impact of Human Papillomavirus (HPV) vaccination in Puerto Rico, a population with considerable burden of HPV-related morbidities. We evaluated the health and economic impacts of implementing a vaccination strategy for females and males in Puerto Rico, with the quadrivalent HPV (HPV4) vaccine, under different vaccination scenarios. METHODS: We adapted a mathematical model which estimates the direct and indirect health benefits and costs of HPV4 vaccination in a dynamic population...
2017: PloS One
https://www.readbyqxmd.com/read/28988463/evidence-against-the-mucosal-traction-theory-in-cholesteatoma
#6
Henrique F Pauna, Rafael C Monsanto, Patricia Schachern, Michael M Paparella, Richard A Chole, Sebahattin Cureoglu
OBJECTIVES: To investigate the distribution of ciliated epithelium in the human middle ear and its potential role in the formation of cholesteatoma. STUDY DESIGN: Comparative human temporal bone study. METHODS: We selected temporal bones from 14 donors with a diagnosis of cholesteatoma, 15 with chronic otitis media without retraction pockets, 14 with chronic otitis media with retraction pockets, 14 with cystic fibrosis (CF), and 16 controls...
October 8, 2017: Laryngoscope
https://www.readbyqxmd.com/read/28980705/empowering-human-cardiac-progenitor-cells-by-p2y-14-nucleotide-receptor-overexpression
#7
Farid G Khalafalla, Waqas Kayani, Arwa Kassab, Kelli Ilves, Megan M Monsanto, Roberto Alvarez, Monica Chavarria, Benjamin Norman, Walter P Dembitsky, Mark A Sussman
KEY POINTS: Autologous cardiac progenitor cell (CPC) therapy is a promising approach for treatment of heart failure (HF). There is an unmet need to identify inherent deficits in aged/diseased human CPCs (hCPCs) derived from HF patients in the attempts to augment their regenerative capacity prior to use in the clinical setting. Here we report significant functional correlations between phenotypic properties of hCPCs isolated from cardiac biopsies of HF patients, clinical parameters of patients and expression of the P2Y14 purinergic receptor (P2Y14 R), a crucial detector for extracellular UDP-sugars released during injury/stress...
December 1, 2017: Journal of Physiology
https://www.readbyqxmd.com/read/28977249/avispora-mochogalegoi-n-sp-apicomplexa-sarcocystidae-in-the-little-owl-athene-noctua-strigiformes-strigidae-in-mainland-portugal
#8
Sergian Vianna Cardozo, Bruno Pereira Berto, Inês Caetano, Viviane Camara Maniero, Marcos Santos, Isabel Pereira da Fonseca, Carlos Wilson Gomes Lopes
The little owl Athene noctua (Scopoli, 1769) is a small raptor that is widely distributed from northern to southern Portugal and several other countries in Europe, Asia and North Africa, and which has been introduced into New Zealand. In the current study, 18 fecal samples were collected from little owls kept at the Lisbon Center for Wild Animal Recovery, which is located in Monsanto Forest Park, Lisbon, Portugal. Twelve (67%) of them were found to be passing an undescribed species of Avispora in their feces...
July 2017: Revista Brasileira de Parasitologia Veterinária, Brazilian Journal of Veterinary Parasitology
https://www.readbyqxmd.com/read/28964299/otologic-manifestations-of-larsen-syndrome
#9
REVIEW
Letícia Helena de Sousa Marques, Daniela Vieira Martins, Gabriel Liria Juares, Fábio Tadeu Moura Lorenzetti, Rafael da Costa Monsanto
OBJECTIVE: To describe and discuss otologic manifestations of Larsen syndrome, based on a case report and a systematic review of the literature. MATERIALS AND METHODS: We performed a PubMED database search, and we selected studies reporting otolaryngologic manifestations secondary to Larsen syndrome. The selected articles were read in full, and three researchers independently extracted data from the studies. In parallel, we report the case of a 14-year-old patient who had hearing loss secondary to Larsen syndrome...
October 2017: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/28923792/p2y-2-nucleotide-receptor-prompts-human-cardiac-progenitor-cell-activation-by-modulating-hippo-signaling
#10
COMPARATIVE STUDY
Farid G Khalafalla, Steven Greene, Hashim Khan, Kelli Ilves, Megan M Monsanto, Roberto Alvarez, Monica Chavarria, Jonathan Nguyen, Benjamin Norman, Walter P Dembitsky, Mark A Sussman
RATIONALE: Autologous stem cell therapy using human c-Kit+ cardiac progenitor cells (hCPCs) is a promising therapeutic approach for treatment of heart failure (HF). However, hCPCs derived from aged patients with HF with genetic predispositions and comorbidities of chronic diseases exhibit poor proliferative and migratory capabilities, which impair overall reparative potential for injured myocardium. Therefore, empowering functionally compromised hCPCs with proregenerative molecules ex vivo is crucial for improving the therapeutic outcome in patients with HF...
November 10, 2017: Circulation Research
https://www.readbyqxmd.com/read/28691661/drosophila-microrna-modulates-viral-replication-by-targeting-a-homologue-of-mammalian-cjun
#11
Verna Monsanto-Hearne, Sultan Asad, Sassan Asgari, Karyn N Johnson
MicroRNAs (miRNAs) are important regulators of biological processes, including host-virus interaction. This study investigated the involvement of Drosophila melanogaster miR-8-5p in host-virus interaction. Drosophila flies and cells challenged with Drosophila C virus (DCV) were found to have lower miR-8-5p abundance compared to uninfected samples. Lowering miR-8-5p abundance by experimental inhibition of the miRNA led to an increase in viral accumulation, suggesting that the observed decrease in the miR-8-5p abundance during DCV infection enhances viral replication...
July 2017: Journal of General Virology
https://www.readbyqxmd.com/read/28680502/pathophysiology-and-diagnosis-of-vertebrobasilar-insufficiency-a-review-of-the-literature
#12
REVIEW
Arlindo Cardoso Lima Neto, Roseli Bittar, Gabriel Scarabotolo Gattas, Edson Bor-Seng-Shu, Marcelo de Lima Oliveira, Rafael da Costa Monsanto, Luis Felipe Bittar
Introduction  Vertebrobasilar insufficiency is defined as transitory ischemia of the vertebrobasilar circulation. Dizziness, vertigo, headaches, vomit, diplopia, blindness, ataxia, imbalance, and weakness in both sides of the body are the most common symptoms. Objective  To review the literature regarding the three available diagnostic testing in patients with dizziness complaints secondary to vertebrobasilar insufficiency (VBI): magnetic resonance angiography; transcranial Doppler ultrasound; and vertebrobasilar deprivation testing...
July 2017: International Archives of Otorhinolaryngology
https://www.readbyqxmd.com/read/28673792/cervical-cerclage-placement-decreases-local-levels-of-proinflammatory-cytokines-in-patients-with-cervical-insufficiency
#13
Stephany P Monsanto, Silvia Daher, Erika Ono, Karen Priscilla Tezotto Pendeloski, Évelyn Trainá, Rosiane Mattar, Chandrakant Tayade
BACKGROUND: Cervical insufficiency is characterized by premature, progressive dilation and shortening of the cervix during pregnancy. If left unattended, this can lead to the prolapse and rupture of the amniotic membrane, which usually results in midtrimester pregnancy loss or preterm birth. Previous studies have shown that proinflammatory cytokines such as interleukin-1β, interleukin-6, interleukin-8, and tumor necrosis factor alpha are up-regulated in normal parturition but are also associated with preterm birth...
October 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28578877/progression-of-changes-in-the-sensorial-elements-of-the-cochlear-and-peripheral-vestibular-systems-the-otitis-media-continuum
#14
Rafael da Costa Monsanto, Patricia Schachern, Michael M Paparella, Sebahattin Cureoglu, Norma de Oliveira Penido
Our study aimed to evaluate pathologic changes in the cochlear (inner and outer hair cells and stria vascularis) and vestibular (vestibular hair cells, dark, and transitional cells) sensorial elements in temporal bones from donors who had otitis media. We studied 40 temporal bones from such donors, which were categorized in serous otitis media (SOM), serous-purulent otitis media (SPOM), mucoid/mucoid-purulent otitis media (MOM/MPOM), and chronic otitis media (COM); control group comprised 10 nondiseased temporal bones...
August 2017: Hearing Research
https://www.readbyqxmd.com/read/28546347/synthetic-msc-nothing-beats-the-real-thing
#15
EDITORIAL
Megan M Monsanto, Bingyan J Wang, Mark A Sussman
No abstract text is available yet for this article.
May 26, 2017: Circulation Research
https://www.readbyqxmd.com/read/28470622/green-synthesis-and-characterization-of-ag-nanoparticles-from-mangifera-indica-leaves-for-dental-restoration-and-antibacterial-applications
#16
Dola Sundeep, T Vijaya Kumar, P S Subba Rao, R V S S N Ravikumar, A Gopala Krishna
Green synthesis has gained a wide recognition as clean synthesis technique in the recent years. In the present investigation, silver nanoparticles were prepared by a novel green synthesis technique using Mangifera indica (Mango leaves) and found to be successfully used in dental applications. The prepared samples were spectroscopically characterized by XRD, PSA, SEM with EDS, and UV-Vis spectroscopy. The crystalline size and lattice strain were analyzed from the XRD data which were counter-verified by W-H plots and particle size analyzer...
May 2017: Progress in Biomaterials
https://www.readbyqxmd.com/read/28446444/concurrent-isolation-of-3-distinct-cardiac-stem-cell-populations-from-a-single-human-heart-biopsy
#17
Megan M Monsanto, Kevin S White, Taeyong Kim, Bingyan J Wang, Kristina Fisher, Kelli Ilves, Farid G Khalafalla, Alexandria Casillas, Kathleen Broughton, Sadia Mohsin, Walter P Dembitsky, Mark A Sussman
RATIONALE: The relative actions and synergism between distinct myocardial-derived stem cell populations remain obscure. Ongoing debates on optimal cell population(s) for treatment of heart failure prompted implementation of a protocol for isolation of multiple stem cell populations from a single myocardial tissue sample to develop new insights for achieving myocardial regeneration. OBJECTIVE: Establish a robust cardiac stem cell isolation and culture protocol to consistently generate 3 distinct stem cell populations from a single human heart biopsy...
July 7, 2017: Circulation Research
https://www.readbyqxmd.com/read/28408123/rna-binding-proteins-in-female-reproductive-pathologies
#18
REVIEW
Kasra Khalaj, Jessica E Miller, Christian R Fenn, SooHyun Ahn, Rayana L Luna, Lindsey Symons, Stephany P Monsanto, Madhuri Koti, Chandrakant Tayade
RNA-binding proteins are key regulatory molecules involved primarily in post-transcriptional gene regulation of RNAs. Post-transcriptional gene regulation is critical for adequate cellular growth and survival. Recent reports have shown key interactions between these RNA-binding proteins and other regulatory elements, such as miRNAs and long noncoding RNAs, either enhancing or diminishing their response to RNA stabilization. Many RNA-binding proteins have been reported to play a functional role in mediation of cytokines involved in inflammation and immune dysfunction, and some have been classified as global post-transcriptional regulators of inflammation...
June 2017: American Journal of Pathology
https://www.readbyqxmd.com/read/28324390/evaluation-of-administered-dose-using-portal-images-in-craniospinal-irradiation-of-pediatric-patients
#19
Carina Marques Coelho, Raquel Calçada, Sofia Rodrigues, Juan Antonio Barragán, Ana Cravo Sá, Ana Paula Macedo, Maria de Fátima Monsanto
This study aimed to assess the administered dose based on portal imaging in craniospinal pediatric irradiation by evaluating cases in which portal images did or did not account for the total administered dose. We also intended to calculate the mean increase in total administered dose. Data were collected from General University Hospital Gregorio Marañón; we evaluated the total dose administered, total dose planned, number of portal images per treatment and corresponding monitor units of two different groups: one in which the dose from portal images is deducted from the total administered dose (D), and another in which it was not (N)...
September 2017: Radiological Physics and Technology
https://www.readbyqxmd.com/read/28286401/histopathology-of-meniere-s-disease
#20
Sebahattin Cureoglu, Rafael da Costa Monsanto, Michael M Paparella
No abstract text is available yet for this article.
December 2016: Operative Techniques in Otolaryngology—Head and Neck Surgery
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