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https://www.readbyqxmd.com/read/28449494/clinical-outcomes-for-multi-and-extensively-drug-resistant-tuberculosis-patients-with-adjunctive-resectional-lung-surgery-in-beijing-china
#1
Yan Ma, Yu Pang, Jian Du, Yuhong Liu, Liang Li, Weiwei Gao
The objective of this study was to assess the performance of adjective resectional lung surgery for multidrug resistant (MDR-) and extensively drug resistant tuberculosis (XDR-TB) patients in Beijing, China. Between October 1992 and October 2012, 21 MDR/XDR patients undergoing pulmonary resection at Beijing Chest Hospital were enrolled in this study. The clinical outcomes of MDR- and XDR-TB patients were analyzed with a 3-year surgical follow-up. Out of 21 patients enrolled in this study, 20 patients (95.2%) had unilateral cavitary disease, and 1 patient (4...
March 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28449408/prediabetes-is-associated-with%C3%A2-genetic-variations-in-the-kir6-2-subunit%C3%A2-kcnj11-%C3%A2-of-pancreatic-atp-sensitive-potassium-channel-gene-a-case-control-study-in-youth-han-chinese-population
#2
Min Xu, Honglin Hu, Datong Deng, Mingwei Chen, Zhenshan Xu, Youmin Wang
BACKGROUND: E23K variant of the KCNJ11 has been reported to be associated with type 2 diabetes in multiple populations. However, little is known about the role of E23K polymorphism of the KCNJ11 in the development of prediabetes in youth in China. METHODS: To this end, we recruited 279 subjects with prediabetes and 240 normal controls. RESULTS: We found that prediabetic Chinese youth exhibited higher carrier rate of K23-allele-containing genotypes than control subjects (p = 0...
April 27, 2017: Journal of Diabetes
https://www.readbyqxmd.com/read/28449358/incident-rate-and-risk-factors-for-tuberculosis-among-patients-with-type-2-diabetes-retrospective-cohort-study-in-shanghai-china
#3
Hanbi Qiu, Yan Shi, Yanyun Li, Xin Shen, Rui Li, Qundi Yang, Qichao Pan, Fei Yan
OBJECTIVE: To examine the incident rate of tuberculosis (TB) and its associates among adults with type 2 diabetes in Shanghai, China. METHODS: We conducted a retrospective cohort study among 170,399 type 2 diabetes patients aged ≥18 years who were registered in Shanghai Community-Based Diabetes Management System between 2004 and 2009. Their TB status was tracked until December 31, 2014. Cox regression was performed to identify the risk factors for TB RESULTS: We documented 785 new TBcases during 654,977 person-years of follow-up...
April 27, 2017: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/28449053/fresh-fruit-consumption-and-all-cause-and-cause-specific-mortality-findings-from-the-china-kadoorie-biobank
#4
Huaidong Du, Liming Li, Derrick Bennett, Ling Yang, Yu Guo, Timothy J Key, Zheng Bian, Yiping Chen, Robin G Walters, Iona Y Millwood, Junshi Chen, Junzheng Wang, Xue Zhou, Le Fang, Yijun Li, Xianzhi Li, Rory Collins, Richard Peto, Zhengming Chen
Background: Higher fruit consumption is associated with lower risk of cardiovascular disease (CVD). Substantial uncertainties remain, however, about the associations of fruit consumption with all-cause mortality and mortality from subtypes of CVD and major non-vascular diseases, especially in China. Methods: In 2004-08, the nationwide China Kadoorie Biobank Study recruited > 0.5 million adults aged 30-79 years from 10 diverse localities in China. Fresh fruit consumption was estimated using an interviewer-administered electronic questionnaire, and mortality data were collected from death registries...
April 24, 2017: International Journal of Epidemiology
https://www.readbyqxmd.com/read/28448927/time-varying-sensitivity-analysis-of-hydrologic-and-sediment-parameters-at-multiple-timescales-implications-for-conservation-practices
#5
Hui Xie, Zhenyao Shen, Lei Chen, Jiali Qiu, Jianwei Dong
Environmental models can be used to better understand the hydrologic and sediment behavior in a watershed system. However, different processes may dominate at different time periods and timescales, which highly complicate the model interpretation. The related parameter uncertainty may be significant and needs to be addressed to avoid bias in the watershed management. In this study, we used the time-varying and multi-timescale (TVMT) method to characterize the temporal dynamics of parameter sensitivity at different timescales in hydrologic and sediment modeling...
April 24, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28448924/sediment-transfer-at-different-spatial-and-temporal-scales-in-the-sichuan-hilly-basin-china-synthesizing-data-from-multiple-approaches-and-preliminary-interpretation-in-the-context-of-climatic-and-anthropogenic-drivers
#6
Valentin Golosov, Adrian L Collins, Qiang Tang, Xinbao Zhang, Ping Zhou, Xiubin He, Anbang Wen
Quantifying sediment production and transfer at different spatial and temporal scales in a changing environment is critical in understanding the potential effects of climatic and anthropogenic drivers. Accordingly, estimates of soil erosion and sediment production at hillslope field, first-order small catchment (<0.25km(2)) and river basin scales in the Sichuan Hilly Basin of Southwestern China, generated using a variety of techniques, including fallout radionuclide tracing, runoff plot observations, core chronology dating and conventional sediment flux monitoring, were synthesized and interpreted in the context of potential climatic and human controls...
April 24, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28448907/characterization-of-typical-metal-particles-during-haze-episodes-in-shanghai-china
#7
Rui Li, Xin Yang, Hongbo Fu, Qingqing Hu, Liwu Zhang, Jianmin Chen
Aerosol particles were collected during three heavy haze episodes at Shanghai in the winter of 2013. Transmission electron microscopy (TEM) coupled with energy dispersive X-ray spectroscopy was used to study the morphology and speciation of typical metal particles at a single-particle level. In addition, time-of-flight aerosol mass spectrometry (ATOFMS) was applied to identify the speciation of the Fe-containing particles. TEM analysis indicated that various metal-containing particles were hosted by sulfates, nitrates, and oxides...
April 19, 2017: Chemosphere
https://www.readbyqxmd.com/read/28448890/metabolic-profiles-of-neotuberostemonine-and-tuberostemonine-in-rats-by-high-performance-liquid-chromatography-quadrupole-time-of-flight-mass-spectrometry
#8
Yongbin Tong, Weitong Xu, Yan Wu, Liting Ou, Mian Zhang, Xianghong Xu, Chaofeng Zhang
Neotuberostemonine (NS) and tuberostemonine (TS), a pair of stereoisomers, are the active components contained in Stemona tuberosa, an antitussive herbal medicine in China. Two isomers have different pharmacological efficacies, which will be related with their in vivo disposition. However, the metabolic fates of NS and TS remain unknown. A method of high performance liquid chromatography/quadrupole time-of-flight mass spectrometry coupled with mass detect filter technique was established to investigate the metabolites in rat plasma, bile, urine, and feces after oral administration of the equal doses of NS and TS...
April 17, 2017: Journal of Pharmaceutical and Biomedical Analysis
https://www.readbyqxmd.com/read/28448739/health-economic-evaluation-of-immunization-strategies-of-hepatitis-e-vaccine-for-elderly-population
#9
Xiaoqing Cheng, Yueyuan Zhao, Xuefeng Zhang, Hui Jin, Jin Min
Objective This study was conducted to assess the cost-effectiveness of hepatitis E vaccination of elderly population in the sporadic regions in China. Methods We used a decision tree-Markov model to evaluate the cost-effectiveness of three kinds of hepatitis E virus vaccination strategies from societal perspectives. Parameter estimates were obtained from published researches and experts' opinion. The time horizon was 16 years, and the discounted rate was 3% annually. Costs are expressed in 2016 US dollars...
April 27, 2017: Human Vaccines & Immunotherapeutics
https://www.readbyqxmd.com/read/28448630/correction-influenza-a-h5n1-and-h7n9-in-china-a-spatial-risk-analysis
#10
Chau Minh Bui, Lauren Gardner, C Raina MacIntyre, Sahotra Sarkar
[This corrects the article DOI: 10.1371/journal.pone.0174980.].
2017: PloS One
https://www.readbyqxmd.com/read/28448628/determinants-of-formal-care-use-and-expenses-among-in-home-elderly-in-jing-an-district-shanghai-china
#11
Fen Li, Xinye Fang, Jiechun Gao, Hansheng Ding, Changying Wang, Chunyan Xie, Yitong Yang, Chunlin Jin
The need for formal care among the elderly population has been increasing due to their greater longevity and the evolution of family structure. We examined the determinants of the use and expenses of formal care among in-home elderly adults in Shanghai. A two-part model based on the data from the Shanghai Long-Term Care Needs Assessment Questionnaire was applied. A total of 8428 participants responded in 2014 and 7100 were followed up in 2015. The determinants of the probability of using formal care were analyzed in the first part of the model and the determinants of formal care expenses were analyzed in the second part...
2017: PloS One
https://www.readbyqxmd.com/read/28448458/does-an-empty-nest-affect-elders-health-empirical-evidence-from-china
#12
Min Gao, Yanyu Li, Shengfa Zhang, Linni Gu, Jinsui Zhang, Zhuojun Li, Weijun Zhang, Donghua Tian
The "empty-nest" elderly family has become increasingly prevalent among old people in China. This study aimed to explore the causality between empty nests and elders' health using effective instrumental variables, including "whether old parents talk with their families when they are upset" and "ownership of housing". The results showed that empty nests had a significantly adverse influence on elders' physical health, cognitive ability and psychological health. Furthermore, urban elders' cognitive ability was more influenced by empty nests than that of rural elders...
April 27, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28448433/prevalence-and-correlates-of-suspected-nonalcoholic-fatty-liver-disease-in-chinese-children
#13
Peige Song, Jinyue Yu, Manli Wang, Xinlei Chang, Jiawen Wang, Lin An
Nonalcoholic fatty liver disease (NAFLD) has become a serious public health problem worldwide; however, the availability of information on the prevalence of NAFLD in the general pediatric population is still limited. The primary aim of this study was to reveal the prevalence and correlates of suspected NAFLD in Chinese children at the national level. Data from the China Health and Nutrition Surveys (CHNS) was used. Weight, height, waist circumference (WC), blood pressure (BP) were measured for children aged 7-18 years...
April 27, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28448400/comparison-of-the-performance-between-sepsis-1-and-sepsis-3-in-icus-in-china-a-retrospective-multicenter-study
#14
Baoli Cheng, Zhongwang Li, Jingya Wang, Guohao Xie, Xu Liu, Zhipeng Xu, Lihua Chu, Jialian Zhao, Yongming Yao, Xiangming Fang
The definition of sepsis was updated to sepsis-3 in February 2016. However, the performance of the previous and new definition of sepsis remains unclear in China. This was a retrospective multicenter study in 6 ICUs from 5 university-affiliated hospitals to compare the performance between sepsis-1 and sepsis-3 in China. From May 1, 2016 to June 1, 2016, 496 patients were enrolled consecutively. Data were extracted from the electronic clinical records. We evaluated the performance of sepsis-1 and sepsis-3 by measuring the area under the receiver operating characteristic curves (AUROC) to predict 28-day mortality rates...
April 26, 2017: Shock
https://www.readbyqxmd.com/read/28448143/effect-directed-analysis-of-toxicants-in-sediment-with-combined-passive-dosing-and-in-vivo-toxicity-testing
#15
Hongxue Qi, Huizhen Li, Yanli Wei, W Tyler Mehler, Eddy Y Zeng, Jing You
Identifying key toxicants in sediment is a great challenge, particularly if non-target toxicants are involved. To identify the contaminants responsible for sediment toxicity to Chironomus dilutus in Guangzhou reach of the Pearl River in South China, passive dosing and in vivo toxicity testing were incorporated into effect-directed analysis (EDA) to account for bioavailability. Fractionation of sediment extracts was performed with gel permeation chromatography and reverse phase liquid chromatography sequentially...
April 27, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/28447904/fine-needle-aspiration-versus-frozen-section-in-the-evaluation-of-malignant-thyroid-nodules-in-patients-with-the-diagnosis-of-suspicious-for-malignancy-or-malignancy-by-fine-needle-aspiration
#16
Qin Ye, Jennifer S Woo, Qunzi Zhao, Ping Wang, Pintong Huang, Lirong Chen, Xin Li, Kanlun Xu, Ying Yong, Stephanie Sung-Eun Yang, Jianyu Rao
CONTEXT: - The Bethesda System for Reporting Thyroid Cytopathology recommends against the use of intraoperative frozen section (FS) during lobectomy of a thyroid nodule with a fine-needle aspiration (FNA) diagnosis of malignant. Bethesda recommendations for FS in the FNA category of suspicious for malignancy (SFM) is less well-defined. In some institutions in China, FS examination is performed during lobectomy even for FNA-proven malignant cases. OBJECTIVE: - -To compare the efficacy of FNA versus FS in the evaluation of malignant thyroid lesions...
May 2017: Archives of Pathology & Laboratory Medicine
https://www.readbyqxmd.com/read/28447797/signal-transductions-of-beas-2b-cells-in-response-to-carcinogenic-pm2-5-exposure-based-on-microfluidic-system
#17
Lulu Zheng, Sixiu Liu, Guoshun Zhuang, Jian Xu, Qi Liu, Xinlian Zhang, Congrui Deng, Zhigang Guo, Wang Zhao, Tingna Liu, Yiqi Wang, Yuxiao Zhang, Jing Lin, Qiongzhen Wang, Guodong Sui
PM2.5 (particulate matter less than 2.5 micrometers in diameter) is considered as a harmful carcinogen. Determining the precise relationship between the chemical constituents of PM2.5 in the air and cancer progression could aid the treatment of environment related disease and establishing risk reduction strategies. Herein, we used transcriptomics (RNA-seq) and integrated microfluidic system to identify the global gene expression and differential target proteins expression induced by ambient fine particles collected from the heavy haze in China...
April 27, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/28447655/march-for-science-climate-engineering-and-china-s-space-station
#18
(no author information available yet)
No abstract text is available yet for this article.
April 26, 2017: Nature
https://www.readbyqxmd.com/read/28447527/serum-thyroid-hormone-levels-among-chinese-pregnant-women
#19
Yunxian Yu, Xiawei Li, Shuying Jiang, Wen Jiang, Jinhua Wu, Zhaopin Wang, Shuojia Wang, Minchao Li, Haigeng Xu, Yun Lv, Jinxing Jiang, Yongfeng Ding, Boer Zhang
AIM: The aim of this study is to examine gestational serum thyroid hormone levels and influencing factors among Chinese pregnant women with high dietary iodine intake. METHODS: The study was conducted from 2011 and 2013 in Zhoushan Women & Children's Hospital, Zhejiang, China. A total of 1991 pregnant women were enrolled and their serum levels of free thyroid hormones (FT4, FT3, and TSH) were detected by chemiluminescence method. RESULTS: Gestational serum FT4 and FT3 decreased with gestational week while TSH increased...
April 27, 2017: Gynecological Endocrinology
https://www.readbyqxmd.com/read/28447395/land-scale-biogeography-of-arsenic-biotransformation-genes-in-estuarine-wetland
#20
Si-Yu Zhang, Jian-Qiang Su, Guo-Xin Sun, Yunfeng Yang, Yi Zhao, Junjun Ding, Yong-Shan Chen, Yu Shen, Guibing Zhu, Christopher Rensing, Yong-Guan Zhu
As an analog of phosphorus, arsenic (As) has a biogeochemical cycle coupled closely with other key elements on the Earth, such as iron, sulfate and phosphate. It has been documented that microbial genes associated with As biotransformation are widely present in As-rich environments. Nonetheless, their presence in natural environment with low As levels remains unclear. To address this issue, we investigated the abundance levels and diversities of aioA, arrA, arsC and arsM genes in estuarine sediments at low As levels across Southeastern China to uncover biogeographic patterns at a large spatial scale...
April 26, 2017: Environmental Microbiology
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