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https://www.readbyqxmd.com/read/29775650/formulants-of-glyphosate-based-herbicides-have-more-deleterious-impact-than-glyphosate-on-tm4-sertoli-cells
#1
Alison Vanlaeys, Florine Dubuisson, Gilles-Eric Seralini, Carine Travert
Roundup and Glyphogan are glyphosate-based herbicides containing the same concentration of glyphosate and confidential formulants. Formulants are declared as inert diluents but some are more toxic than glyphosate, such as the family of polyethoxylated alkylamines (POEA). We tested glyphosate alone, glyphosate-based herbicide formulations and POEA on the immature mouse Sertoli cell line (TM4), at concentrations ranging from environmental to agricultural-use levels. Our results show that formulations of glyphosate-based herbicides induce TM4 mitochondrial dysfunction (like glyphosate, but to a lesser extent), disruption of cell detoxification systems, lipid droplet accumulation and mortality at sub-agricultural doses...
May 15, 2018: Toxicology in Vitro: An International Journal Published in Association with BIBRA
https://www.readbyqxmd.com/read/29771587/the-roundup-a-compilation-of-items-about-healthcare-technology-news-regulations-and-aami-initiatives
#2
Barbara L Christe, Mary Ann Drosnock, Samantha Jacques, Sandy Morford, Robert Sayle
No abstract text is available yet for this article.
May 2018: Biomedical Instrumentation & Technology
https://www.readbyqxmd.com/read/29705296/glyphosate-affects-the-secretion-of-regulators-of-uterine-contractions-in-cows-while-it-does-not-directly-impair-the-motoric-function-of-myometrium-in-vitro
#3
Wrobel Michael Hubert
The effects of pure glyphosate and its most popular product (brand name: Roundup) on the secretion of hormones involved in the regulation of myometrial contractions as well as their direct effects on myometrial contractions were examined. Myometrial strips as well as uterine and ovarian cells were taken from cows during the oestrous cycle and they were treated with both compounds at concentrations from their environmental range. Glyphosate stimulated the secretion of oestradiol from granulosa cells while both herbicides increased and decreased oxytocin (OT) and progesterone secretion from luteal cells respectively...
April 26, 2018: Toxicology and Applied Pharmacology
https://www.readbyqxmd.com/read/29703108/research-roundup
#4
John Costello
Synopses of a selection of recently published research articles of relevance to palliative care.
April 2, 2018: International Journal of Palliative Nursing
https://www.readbyqxmd.com/read/29627927/the-effects-of-roundup-on-gametes-and-early-development-of-common-carp-cyprinus-carpio-l
#5
Katarzyna Lugowska
To determine the effects of Roundup, a commercial formulation of glyphosate, gametes, and embryos of common carp (Cyprinus carpio L) was exposed to wide range of herbicide concentrations (0.0, 0.1, 0.5, 2.0, 5.0, 10.0, 20.0, and 50.0 mg/l). The obtained results showed different effects of Roundup on common carp gametes. Herbicide reduced swelling of eggs (but the effect was not concentration-related), while sperm showed low sensitivity to Roundup (time of spermatozoa motility was reduced in a significant way only at 20 mg/l, and at remaining concentrations, only a slight tendency was observed)...
April 7, 2018: Fish Physiology and Biochemistry
https://www.readbyqxmd.com/read/29614449/cytogenetic-damage-in-peripheral-blood-cultures-of-chaetophractus-villosus-exposed-in-vivo-to-a-glyphosate-formulation-roundup
#6
Luis Francisco Rossi, Juan Pablo Luaces, Ana Maria Palermo, María Susana Merani, Marta Dolores Mudry
Different concentrations of a glyphosate formulation, Roundup® Full II (66.2% glyphosate) were tested in culture peripheral blood of armadillo Chaetophractus villosus with cytogenetic biomarkers like mitotic index (MI), chromosomal aberrations (CA), sister chromatid exchange (SCE) and cell proliferation kinetics (CPK) by means of replication index. Adults animals of both sexes were exposed to RU at four concentrations ranging from 0.026 mL RU solution to 0.379 mL RU daily in oral treatment with the same volume (0...
March 31, 2018: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/29614408/mixture-of-commercial-herbicides-based-on-2-4-d-and-glyphosate-mixture-can-suppress-the-emergence-of-zooplankton-from-sediments
#7
Jorge L Portinho, Daryl L Nielsen, Luana Daré, Raoul Henry, Régis C Oliveira, Ciro C Z Branco
It is generally assumed that zooplankton can recolonize lakes that have been exposed to pesticides, via their dormant egg banks. Hitherto, few studies have evaluated the relative importance of dormant egg bank recruitment in the re-establishment of zooplankton communities in the presence of pesticide. This study investigated the effects of commercial products Bratt® (a.i. 2,4-D), Roundup® (a.i. glyphosate) and their mixture on the emergence (abundance and taxon richness) of dormant zooplankton egg banks from natural lake sediment...
March 23, 2018: Chemosphere
https://www.readbyqxmd.com/read/29609161/electrochemical-genoassays-on-gold-coated-magnetic-nanoparticles-to-quantify-genetically-modified-organisms-gmos-in-food-and-feed-as-gmo-percentage
#8
Alexandra Plácido, Clara Pereira, Alexandra Guedes, M Fátima Barroso, Rebeca Miranda-Castro, Noemí de-Los-Santos-Álvarez, Cristina Delerue-Matos
The integration of nanomaterials in the field of (bio)sensors has allowed developing strategies with improved analytical performance. In this work, ultrasmall core-shell Fe3 O4 @Au magnetic nanoparticles (MNPs) were used as the platform for the immobilization of event-specific Roundup Ready (RR) soybean and taxon-specific DNA sequences. Firstly, monodisperse Fe3 O4 MNPs were synthesized by thermal decomposition and subsequently coated with a gold shell through reduction of Au(III) precursor on the surface of the MNPs in the presence of an organic capping agent...
March 21, 2018: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/29608381/research-roundup
#9
John Costello
Synopses of a selection of recently published research articles of relevance to palliative care.
March 2, 2018: International Journal of Palliative Nursing
https://www.readbyqxmd.com/read/29593778/evaluation-of-reference-genes-to-analyze-gene-expression-in-silverside-odontesthes-humensis-under-different-environmental-conditions
#10
Tony L R Silveira, William B Domingues, Mariana H Remião, Lucas Santos, Bruna Barreto, Ingrid M Lessa, Antonio Sergio Varela Junior, Diego Martins Pires, Carine Corcini, Tiago Collares, Fabiana K Seixas, Ricardo B Robaldo, Vinicius F Campos
Some mammalian reference genes, which are widely used to normalize the qRT-PCR, could not be used for this purpose due to its high expression variation. The normalization with false reference genes leads to misinterpretation of results. The silversides ( Odontesthes spp.) has been used as models for evolutionary, osmoregulatory and environmental pollution studies but, up to now, there are no studies about reference genes in any Odontesthes species. Furthermore, many studies on silversides have used reference genes without previous validations...
2018: Frontiers in Genetics
https://www.readbyqxmd.com/read/29573614/effects-of-glyphosate-and-its-commercial-formulation-roundup-%C3%A2-ultramax-on-liver-histology-of-tadpoles-of-the-neotropical-frog-leptodactylus-latrans-amphibia-anura
#11
Nadia C Bach, Damián J G Marino, Guillermo S Natale, Gustavo M Somoza
In the last years, the agricultural expansion has led to an increased use of pesticides, with glyphosate as the most widely used worldwide. This is also the situation in Argentina, where glyphosate formulations are the most commercialized herbicides. It is known that glyphosate formulations are much more toxic than the active ingredient, and this difference in toxicity can be attributed to the adjuvants present in the formula. In this context, the aim of the present study was to evaluate and compare sub-lethal histological effects of the glyphosate formulation Roundup Ultramax and glyphosate active ingredient on Leptodactylus latrans tadpoles at Gosner-stage 36...
March 17, 2018: Chemosphere
https://www.readbyqxmd.com/read/29558175/the-roundup-a-compilation-of-items-about-healthcare-technology-news-regulations-and-aami-initiatives
#12
(no author information available yet)
No abstract text is available yet for this article.
March 2018: Biomedical Instrumentation & Technology
https://www.readbyqxmd.com/read/29550438/evaluating-the-impact-of-synthetic-herbicides-on-soil-dwelling-macrobes-and-the-physical-state-of-soil-in-an-agro-ecosystem
#13
J O Frimpong, E S K Ofori, S Yeboah, D Marri, B K Offei, F Apaatah, J O Sintim, E Ofori-Ayeh, M Osae
This study evaluated three herbicides active ingredients: Paraquat, Glyphosate and 2,4-D Amine in commercial formulations as Frankoquat, Roundup and Agriherb respectively under field conditions to determine their influence on soil dwelling macrobes and the physical state of soil. Herbicides were serially diluted to three treatment concentrations for each plus three controls. Herbicide concentrations were applied to the demarcated field on three consecutive occasions in splits. Macrobes extraction from soil was done under a stereo microscope at 20 × magnification...
March 15, 2018: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/29542046/effect-of-glyphosate-based-herbicide-on-hematological-and-hemopoietic-parameters-in-common-carp-cyprinus-carpio-l
#14
E Kondera, B Teodorczuk, K Ługowska, M Witeska
The effects of Roundup (glyphosate-based herbicide) on peripheral blood parameters and hematopoietic tissue cellular composition and activity in common carp juveniles were evaluated. The fish were exposed for 7 days at 0.0, 0.1, 0.5, or 5.0 mg/L of glyphosate. In fish exposed to Roundup, hematological alterations were observed; however, most of them were not directly related to the herbicide concentration. An increase in Ht and MCV, and decrease in Hb, MCH, and MCHC compared to the control were observed. Fish exposed to Roundup showed also a reduction in WBC and oxidative metabolic activity of phagocytes (NBT) compared to the control...
March 14, 2018: Fish Physiology and Biochemistry
https://www.readbyqxmd.com/read/29540978/threshold-level-and-traceability-of-roundup-ready%C3%A2-soybeans-in-tofu-production
#15
Zorica Nikolić, Gordana Petrović, Dejana Panković, Maja Ignjatov, Dragana Marinković, Milan Stojanović, Vuk Đorđević
The aim of this study is to assess DNA degradation, DNA amplification, and GMO quantity during tofu production. Soybean seeds were spiked with Roundup Ready® soybeans (RRS) at 0.9, 2, 3 and 5% (by mass), to assess the level of RSS that would be of practical interest for threshold labelling. Real-time polymerase chain reaction (PCR) was more effective than conventional PCR in the analysis of raw soymilk, okara, boiled soymilk and tofu. The negative effect of grinding and mechanical manipulation was obvious in the okara sample prepared with 3 and 5% RRS, where GMO content was reduced to (2...
December 2017: Food Technology and Biotechnology
https://www.readbyqxmd.com/read/29518655/label-free-optical-biosensor-for-real-time-monitoring-the-cytotoxicity-of-xenobiotics-a-proof-of-principle-study-on-glyphosate
#16
Eniko Farkas, Andras Szekacs, Boglarka Kovacs, Marianna Olah, Robert Horvath, Inna Szekacs
Rapid and inexpensive biosensor technologies allowing real-time analysis of biomolecular and cellular events have become the basis of next-generation cell-based screening techniques. Our work opens up novel opportunities in the application of the high-throughput label-free Epic BenchTop optical biosensor in cell toxicity studies. The Epic technology records integrated cellular responses about changes in cell morphology and dynamic mass redistribution of cellular contents at the 100-150 nm layer above the sensor surface...
June 5, 2018: Journal of Hazardous Materials
https://www.readbyqxmd.com/read/29469644/research-roundup
#17
John Costello
Synopses of a selection of recently published research articles of relevance to palliative care.
February 2, 2018: International Journal of Palliative Nursing
https://www.readbyqxmd.com/read/29466501/morphological-effects-on-helminth-parasites-caused-by-herbicide-under-experimental-conditions
#18
Tainá Carneiro de Castro Monte, Brunna Vianna Braga, Maurício Carvalho de Vasconcellos, Arnon Dias Jurberg, Ester Maria Mota, Helene Santos Barbosa, Juberlan Silva Garcia, Arnaldo Maldonado Júnior
Helminth parasites have been studied as potential accumulators for different pollutants. Echinostoma paraensei is a foodborne trematode whose vertebrate host, the rodent Nectomys squamipes, is naturally exposed to environmental pesticides. However, little information exists regarding the pesticide's effects on helminths. This study investigated the morphological effects on the trematode, E. paraensei, after experimental Roundup® herbicide exposure, in concentrations below those recommended for agricultural use...
February 19, 2018: Revista Brasileira de Parasitologia Veterinária, Brazilian Journal of Veterinary Parasitology
https://www.readbyqxmd.com/read/29460795/evidence-the-u-s-autism-epidemic-initiated-by-acetaminophen-tylenol-is-aggravated-by-oral-antibiotic-amoxicillin-clavulanate-augmentin-and-now-exponentially-by-herbicide-glyphosate-roundup
#19
Peter Good
Because certain hereditary diseases show autistic behavior, and autism often runs in families, researchers seek genes underlying the pathophysiology of autism, thus core behaviors. Other researchers argue environmental factors are decisive, citing compelling evidence of an autism epidemic in the United States beginning about 1980. Recognition that environmental factors influence gene expression led to synthesis of these views - an 'epigenetic epidemic' provoked by pervasive environmental agents altering expression of vulnerable genes, inducing characteristic autistic biochemistries in many mothers and infants...
February 2018: Clinical Nutrition ESPEN
https://www.readbyqxmd.com/read/29442306/protective-effect-of-uncaria-tomentosa-extract-against-oxidative-stress-and-genotoxicity-induced-by-glyphosate-roundup%C3%A2-using-zebrafish-danio-rerio-as-a-model
#20
Glaucia Dal Santo, Alan Grotto, Aline A Boligon, Bárbara Da Costa, Cassiano L Rambo, Emily A Fantini, Elisa Sauer, Luan M V Lazzarotto, Kanandra T Bertoncello, Osmar Tomazelli Júnior, Solange C Garcia, Anna M Siebel, Denis B Rosemberg, Jacir Dal Magro, Greicy M M Conterato, Leila Zanatta
Oxidative stress and DNA damage are involved in the glyphosate-based herbicide toxicity. Uncaria tomentosa (UT; Rubiaceae) is a plant species from South America containing bioactive compounds with known beneficial properties. The objective of this work was to evaluate the antioxidant and antigenotoxic potential of UT extract in a model of acute exposure to glyphosate-Roundup® (GR) in zebrafish (Danio rerio). We showed that UT (1.0 mg/mL) prevented the decrease of brain total thiols, the increase of lipid peroxidation in both brain and liver, and the decrease of liver GPx activity caused after 96 h of GR (5...
February 13, 2018: Environmental Science and Pollution Research International
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