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https://www.readbyqxmd.com/read/28900029/young-adulthood-and-adulthood-adiposity-in-relation-to-incidence-of-pancreatic-cancer-a-prospective-study-of-0-5-million-chinese-adults-and-a-meta-analysis
#1
Yuanjie Pang, Michael V Holmes, Christiana Kartsonaki, Yu Guo, Ling Yang, Zheng Bian, Yiping Chen, Fiona Bragg, Andri Iona, Iona Y Millwood, Junshi Chen, Liming Li, Zhengming Chen
BACKGROUND: Adult adiposity is positively associated with pancreatic cancer in Western populations. Little is known, however, about the association in China where many have lower body mass index (BMI) or about the relevance of young adulthood adiposity for pancreatic cancer in both Western and East Asian populations. METHODS: The China Kadoorie Biobank (CKB) recruited 512 891 adults aged 30-79 years during 2004-2008, recording 595 incident cases of pancreatic cancer during 8-year follow-up...
September 12, 2017: Journal of Epidemiology and Community Health
https://www.readbyqxmd.com/read/28738458/-associations-between-season-of-birth-and-age-both-at-menarche-and-at-menopause
#2
J H Si, R R Meng, J Lyu, Y Guo, Z Bian, C Q Yu, L Yang, Y L Tan, P Pei, J S Chen, Z M Chen, L M Li
Objective: To examine the associations between season of birth and factors as age at menarche, age at menopause and reproductive span. Methods: A total of 285 186 female from the China Kadoorie Biobank, with complete data on critical variables and had menarche at 9-18 years old, were included. A total of 132 373 female with natural menopause were included for the analysis on age at menopause and reproductive span. Multiple linear regression models were used to assess the associations of birth season and the age at menarche, menopause, and reproductive span...
July 10, 2017: Zhonghua Liu Xing Bing Xue za Zhi, Zhonghua Liuxingbingxue Zazhi
https://www.readbyqxmd.com/read/28651394/-relationship-between-sleep-status-and-the-risk-of-diabetes-in-adults
#3
J Su, R Tao, J Y Zhou, J Yang, Y Qin, Y H Hu, Y Lu, J R Jin, Z Bian, Y Guo, Z M Chen, L M Li, M Wu
Objective: To explore the relationship between sleep status and the risk of diabetes in adults. Methods: The baseline data of 53 260 subjects who were aged 30-79 years and had been enrolled into China Kadoorie Biobank (CKB) study from Suzhou, Jiangsu province were analyzed. Multiple logistic regression models were used to investigate the association between sleep status and diabetes after adjusting for potential confounders. Results: Among 53 260 subjects, 5.3% had diabetes. The proportions of difficultly falling asleep, early morning arousal and snoring frequently was 7...
May 10, 2017: Zhonghua Liu Xing Bing Xue za Zhi, Zhonghua Liuxingbingxue Zazhi
https://www.readbyqxmd.com/read/28637778/breastfeeding-and-the-risk-of-maternal-cardiovascular-disease-a-prospective-study-of-300%C3%A2-000-chinese-women
#4
Sanne A E Peters, Ling Yang, Yu Guo, Yiping Chen, Zheng Bian, Jianwei Du, Jie Yang, Shanpeng Li, Liming Li, Mark Woodward, Zhengming Chen
BACKGROUND: Breastfeeding confers substantial benefits to child health and has also been associated with lower risk of maternal cardiovascular diseases (CVDs) in later life. However, the evidence on the effects of CVD is still inconsistent, especially in East Asians, in whom the frequency and duration of breastfeeding significantly differ from those in the West. METHODS AND RESULTS: In 2004-2008, the nationwide China Kadoorie Biobank recruited 0.5 million individuals aged 30 to 79 years from 10 diverse regions across China...
June 21, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/28605451/age-at-menarche-and-incidence-of-diabetes-a-prospective-study-of-300-000-women-in-china
#5
Ling Yang, Liming Li, Sanne A E Peters, Robert Clarke, Yu Guo, Yiping Chen, Zheng Bian, Paul Sherliker, Jiyuan Yin, Zhenzhu Tang, Chunmei Wang, Xiaohuan Wang, Libo Zhang, Mark Woodward, Zhengming Chen
Previous studies of mostly Western populations have reported inconsistent associations between age at menarche and risk of diabetes. We examined such associations among Chinese women who tend to have later menarche age than women in West. China Kadoorie Biobank recruited 302,632 women aged 30-79 years from 10 areas across China in 2004-8, recording 5,391 incident cases of diabetes during 7-years follow-up among 270,345 women without diabetes, cardiovascular disease or cancer at baseline. Cox regression models yielded adjusted hazard ratios (HRs) for incident diabetes associated with age at menarche...
June 9, 2017: American Journal of Epidemiology
https://www.readbyqxmd.com/read/28593646/cancer-incidence-and-mortality-a-cohort-study-in-china-2008-2013
#6
Rui Pan, Meng Zhu, Canqing Yu, Jun Lv, Yu Guo, Zheng Bian, Ling Yang, Yiping Chen, Zhibin Hu, Zhengming Chen, Liming Li, Hongbing Shen
The National Central Cancer Registry of China (NCCR) was the only available source of cancer monitoring in China, even though only about 70% of cancer registration sites were qualified by now. In this study, based on a national large prospective cohort-the China Kadoorie Biobank (CKB), we aimed to provide additional cancer statistics and compare the difference of cancer burden between urban and rural areas of China. A total of 497,693 cancer-free participants aged 35-74 years were recruited and successfully followed up from 2004 to 2013 in 5 urban and 5 rural areas across China...
October 1, 2017: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/28592782/family-history-and-stroke-risk-in-china-evidence-from-a-large-cohort-study
#7
Tian Tian, Guangfu Jin, Canqing Yu, Jun Lv, Yu Guo, Zheng Bian, Ling Yang, Yiping Chen, Hongbing Shen, Zhengming Chen, Zhibin Hu, Liming Li
BACKGROUND AND PURPOSE: Large cohort studies on relationship between family history of stroke (FHS) and stroke risk are lacking in Asians. We aimed to systematically evaluate the association of FHS with stroke risk in a cohort study of 0.5 million Chinese adults. METHODS: Information about FHS was self-reported. The median follow-up time was 7.16 years and the end-point of follow-up was incident stroke, which was entered directly into the China Kadoorie Biobank system...
May 2017: Journal of Stroke
https://www.readbyqxmd.com/read/28582543/adherence-to-a-healthy-lifestyle-and-the-risk-of-type-2-diabetes-in-chinese-adults
#8
Jun Lv, Canqing Yu, Yu Guo, Zheng Bian, Ling Yang, Yiping Chen, Ximin Hu, Wei Hou, Junshi Chen, Zhengming Chen, Lu Qi, Liming Li
Background: Simultaneously adhering to multiple healthy lifestyle factors has been related to up to 90% reduction in type 2 diabetes (T2DM) incidence in White populations; however, little is known about whether such protective effects persist in other non-White populations. Methods: We examined the associations of six lifestyle factors with T2DM in the China Kadoorie Biobank of 461 211 participants aged 30-79 years without diabetes, cardiovascular diseases or cancer at baseline...
June 3, 2017: International Journal of Epidemiology
https://www.readbyqxmd.com/read/28468061/-distributions-and-associations-between-duration-of-sleep-daytime-naps-and-insomnia-symptoms-among-chinese-adults
#9
B Zheng, L L Lin, C Q Yu, J Lyu, Y Guo, Z Bian, Y L Tan, P Pei, J S Chen, Z M Chen, L M Li
Objective: To investigate the distribution of sleep duration, daytime naps habits, and insomnia-related symptoms among participants from the China Kadoorie Biobank (CKB) study, and to examine the associations between the sleep-associated factors. Methods: A self-designed computer-based questionnaire was adopted to collect social-demographic information and lifestyle-related factors of the participants. A total of 452 829 Chinese adults aged 30-79 years, without self-reported histories of coronary heart disease, stroke, chronic obstructive pulmonary diseases or cancer, were included in this study...
April 10, 2017: Zhonghua Liu Xing Bing Xue za Zhi, Zhonghua Liuxingbingxue Zazhi
https://www.readbyqxmd.com/read/28468060/-associations-between-airflow-obstruction-and-the-risks-of-morbidity-on-major-chronic-diseases-in-chinese-adults-a-prospective-cohort-study
#10
J C Li, F L Lan, C Q Yu, J Lyu, Y Guo, Z Bian, Y L Tan, P Pei, J S Chen, Z M Chen, L M Li
Objective: To examine the prospective associations between airflow obstruction (AFO) and risks of major chronic diseases morbidity in Chinese adults. Methods: Samples of this study were from the China Kadoorie Biobank. A total of 486 996 participants aged 30 to 79 years (mean 51.5 years) at the baseline study, were included after excluding those who self-reported of having heart disease, stroke and cancer at baseline. AFO was defined under the Global Initiative on Obstructive Lung Disease (GOLD) criteria and forced expiratory volume per one second in percentage of the expected one (FEV(1)% P)...
April 10, 2017: Zhonghua Liu Xing Bing Xue za Zhi, Zhonghua Liuxingbingxue Zazhi
https://www.readbyqxmd.com/read/28449053/fresh-fruit-consumption-and-all-cause-and-cause-specific-mortality-findings-from-the-china-kadoorie-biobank
#11
Huaidong Du, Liming Li, Derrick Bennett, Ling Yang, Yu Guo, Timothy J Key, Zheng Bian, Yiping Chen, Robin G Walters, Iona Y Millwood, Junshi Chen, Junzheng Wang, Xue Zhou, Le Fang, Yijun Li, Xianzhi Li, Rory Collins, Richard Peto, Zhengming Chen
Background: Higher fruit consumption is associated with lower risk of cardiovascular disease (CVD). Substantial uncertainties remain, however, about the associations of fruit consumption with all-cause mortality and mortality from subtypes of CVD and major non-vascular diseases, especially in China. Methods: In 2004-08, the nationwide China Kadoorie Biobank Study recruited > 0.5 million adults aged 30-79 years from 10 diverse localities in China. Fresh fruit consumption was estimated using an interviewer-administered electronic questionnaire, and mortality data were collected from death registries...
April 24, 2017: International Journal of Epidemiology
https://www.readbyqxmd.com/read/28407795/the-association-between-self-rated-health-and-different-anthropometric-and-body-composition-measures-in-the-chinese-population
#12
Kun Tang, Yingxi Zhao, Chunyan Li
BACKGROUND: To analyze the strength of association between self-rated health and six anthropometric and body composition measures to explore the best indicator. METHODS: Analyses were based on the cross-sectional data from the China Kadoorie Biobank Study and approximately 300,000 adults were analyzed. Logistics regression was used to analyze the association between self-rated health (good or poor) and anthropometric and body composition measures (height, weight, body mass index (BMI), waist circumference (WC), hip circumference (HC) and body fat percentage, waist-to-hip ratio and waist-to-height ratio)...
April 13, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28403155/fruit-consumption-and-physical-activity-in-relation-to-all-cause-and-cardiovascular-mortality-among-70-000-chinese-adults-with-pre-existing-vascular-disease
#13
Xiaocao Tian, Huaidong Du, Liming Li, Derrick Bennett, Ruqin Gao, Shanpeng Li, Shaojie Wang, Yu Guo, Zheng Bian, Ling Yang, Yiping Chen, Junshi Chen, Yan Gao, Min Weng, Zengchang Pang, Baofa Jiang, Zhengming Chen
OBJECTIVES: To assess the associations of fresh fruit consumption and total physical activity with all-cause and cardiovascular mortality among Chinese adults who have been diagnosed with cardiovascular disease (CVD) or hypertension. METHODS: During 2004-08, the China Kadoorie Biobank study recruited 70,047 adults, aged 30-79 years, with physician-diagnosed stroke or transient ischaemic attack, ischemic heart disease, or hypertension. Information on diet and physical activity was collected using an interviewer-administered electronic questionnaire...
2017: PloS One
https://www.readbyqxmd.com/read/28399126/fresh-fruit-consumption-in-relation-to-incident-diabetes-and-diabetic-vascular-complications-a-7-y-prospective-study-of-0-5-million-chinese-adults
#14
Huaidong Du, Liming Li, Derrick Bennett, Yu Guo, Iain Turnbull, Ling Yang, Fiona Bragg, Zheng Bian, Yiping Chen, Junshi Chen, Iona Y Millwood, Sam Sansome, Liangcai Ma, Ying Huang, Ningmei Zhang, Xiangyang Zheng, Qiang Sun, Timothy J Key, Rory Collins, Richard Peto, Zhengming Chen
BACKGROUND: Despite the well-recognised health benefits of fresh fruit consumption, substantial uncertainties remain about its potential effects on incident diabetes and, among those with diabetes, on risks of death and major vascular complications. METHODS AND FINDINGS: Between June 2004 and July 2008, the nationwide China Kadoorie Biobank study recruited 0.5 million adults aged 30-79 (mean 51) y from ten diverse localities across China. During ~7 y of follow-up, 9,504 new diabetes cases were recorded among 482,591 participants without prevalent (previously diagnosed or screen-detected) diabetes at baseline, with an overall incidence rate of 2...
April 2017: PLoS Medicine
https://www.readbyqxmd.com/read/28335373/dietary-patterns-and-insomnia-symptoms-in-chinese-adults-the-china-kadoorie-biobank
#15
Canqing Yu, Zumin Shi, Jun Lv, Yu Guo, Zheng Bian, Huaidong Du, Yiping Chen, Ran Tao, Ying Huang, Junshi Chen, Zhengming Chen, Liming Li
Limited attention has been paid to the effect of dietary patterns on sleep problems. In the present study, we analyzed the cross-sectional data of 481,242 adults aged 30-79 years from the China Kadoorie Biobank. A laptop-based questionnaire was administered to collect information on food intakes and insomnia symptoms. Logistic regression was used to estimate the odds ratios of each insomnia symptom according to quartiles of each dietary pattern, with adjustment for potential confounders. Two major dietary patterns were derived by factor analysis...
March 4, 2017: Nutrients
https://www.readbyqxmd.com/read/28268813/risk-prediction-for-cardiovascular-disease-using-ecg-data-in-the-china-kadoorie-biobank
#16
Yanting Shen, Yang Yang, Sarah Parish, Zhengming Chen, Robert Clarke, David A Clifton
We set out to use machine learning techniques to analyse ECG data to improve risk evaluation of cardiovascular disease in a very large cohort study of the Chinese population. We performed this investigation by (i) detecting "abnormality" using 3 one-class classification methods, and (ii) predicting probabilities of "normality", arrhythmia, ischemia, and hypertrophy using a multiclass approach. For one-class classification, we considered 5 possible definitions for "normality" and used 10 automatically-extracted ECG features along with 4 blood pressure features...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28259178/factors-associated-with-spontaneous-abortion-a-cross-sectional-study-of-chinese-populations
#17
Danni Zheng, Chunyan Li, Taiwen Wu, Kun Tang
BACKGROUND: Spontaneous abortion (SA) is one of the prevalent negative reproductive outcomes among women around the world, which is a great challenge faced by maternal health promotion. The present study is aimed to explore the association between SA and socioeconomic status (SES) and provides reference for policy makers to improve strategies on maternal health promotion. METHODS: A cross-sectional analysis was conducted with baseline data from a large-scale population-based cohort study of 0...
March 4, 2017: Reproductive Health
https://www.readbyqxmd.com/read/28254173/adherence-to-healthy-lifestyle-and-cardiovascular-diseases-in-the-chinese%C3%A2-population
#18
Jun Lv, Canqing Yu, Yu Guo, Zheng Bian, Ling Yang, Yiping Chen, Xuefeng Tang, Weiyuan Zhang, Yijian Qian, Yuelong Huang, Xiaoping Wang, Junshi Chen, Zhengming Chen, Lu Qi, Liming Li
BACKGROUND: Adherence to a combination of healthy lifestyle factors has been related to a considerable reduction of cardiovascular risk in white populations; however, little is known whether such associations persist in nonwhite populations like the Asian population. OBJECTIVES: This study aimed to examine the associations of a combination of modifiable, healthy lifestyle factors with the risks of ischemic cardiovascular diseases and estimate the proportion of diseases that could potentially be prevented by adherence to these healthy lifestyle patterns...
March 7, 2017: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/28231667/-association-between-body-mass-index-and-both-total-and-cause-specific-mortality-in-china-findings-from-data-through-the-china-kadoorie-biobank
#19
L X Wang, M Y Fan, C Q Yu, Y Guo, Z Bian, Y L Tan, P Pei, J S Chen, J Lyu, L M Li
Objective: To evaluate the associations between body mass index (BMI) and both total and cause-specific mortality. Methods: After excluding participants with heart disease, stroke, cancer, chronic obstructive pulmonary disease, and diabetes at baseline study, 428 593 participants aged 30-79 in the China Kadoorie Biobank study were chosen for this study. Participants were categorized into 9 groups according to their BMI status. Cox regression analysis was used to estimate the hazard ratios (HRs) and 95% confidence intervals (CIs) of mortality on BMI...
February 10, 2017: Zhonghua Liu Xing Bing Xue za Zhi, Zhonghua Liuxingbingxue Zazhi
https://www.readbyqxmd.com/read/28230295/associations-of-domain-specific-physical-activities-with-insomnia-symptoms-among-0-5-million-chinese-adults
#20
Bang Zheng, Canqing Yu, Liling Lin, Huaidong Du, Jun Lv, Yu Guo, Zheng Bian, Yiping Chen, Min Yu, Jianguo Li, Junshi Chen, Zhengming Chen, Liming Li
Previous studies have demonstrated the association between physical activity and sleep quality. However, there is little evidence regarding different domains of physical activity. This study aimed to examine the associations between domain-specific physical activities and insomnia symptoms among Chinese men and women. Data of 452 024 Chinese adults aged 30-79 years from the China Kadoorie Biobank Study were analysed. Insomnia symptoms were assessed with self-reported difficulties in initiating or maintaining sleep, early morning awakening, daytime dysfunction and any insomnia symptoms...
June 2017: Journal of Sleep Research
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