keyword
MENU ▼
Read by QxMD icon Read
search

Ochratoxin

keyword
https://www.readbyqxmd.com/read/28221957/ochratoxin-a-concentrations-in-a-variety-of-grain-based-and-non-grain-based-foods-on-the-canadian-retail-market-from-2009-to-2014
#1
Beata Kolakowski, Sarah M O'Rourke, Henri P Bietlot, Karl Kurz, Barbara Aweryn
The extent of ochratoxin A (OTA) contamination of domestically produced foods sold across Canada was determined from 2009 to 2014 with sampling and testing occurring each fiscal year. Cereal-based, fruit-based, and soy-based food samples (n = 6,857) were analyzed. Almost half of the samples (3,200; 47%) did not contain detectable concentrations of OTA. The remaining 3,657 samples contained OTA at 0.040 to 631 ng/g. Wheat, oats, milled products of other grains (such as rye and buckwheat), and to a lesser extent corn products and their derived foods were the most significant potential sources of OTA exposure for the Canadian population...
December 2016: Journal of Food Protection
https://www.readbyqxmd.com/read/28221942/effect-of-fungicides-on-growth-and-ochratoxin-a-production-by-aspergillus-carbonarius-from-brazilian-wine-grapes
#2
Michelle F Terra, Nathasha de A Lira, Fabiana R F Passamani, Wilder Douglas Santiago, Maria das Graças Cardoso, Luís Roberto Batista
Prevention in the field of mycotoxin-producing fungi is the most effective strategy for controlling the presence of mycotoxins in foods. Chemical fungicides are widely used to protect crops, so their implications on mycotoxin production need to be considered. Therefore, the aim of this study was to evaluate the effect in vitro and on grapes of five fungicides commonly used on grape cultures in Brazil on Aspergillus carbonarius growth and ochratoxin A (OTA) production. At the doses recommended by manufacturers, most fungicides significantly reduced A...
September 2016: Journal of Food Protection
https://www.readbyqxmd.com/read/28221848/heat-stability-of-ochratoxin-a-in-an-aqueous-buffered-model-system
#3
Samjhana Dahal, Hyun Jung Lee, Kejia Gu, Dojin Ryu
Ochratoxin A (OTA) represents one of the most widespread mycotoxins in agricultural commodities in the world and is considered a possible human carcinogen with its potent nephrotoxicity. OTA is stable under most food processing conditions; however, higher-temperature treatment may reduce OTA content in foods. Since OTA can be found in processed products destined for both human and animal consumption, factors affecting its stability or reduction during thermal processes were investigated here. The reduction of OTA was measured during various heating times (up to 60 min) at different temperatures (100, 125, 150, 175, and 200°C) in aqueous buffer solutions at different pHs (pH 4, 7, and 10)...
October 2016: Journal of Food Protection
https://www.readbyqxmd.com/read/28218865/occurrence-of-ochratoxin-a-in-infant-foods-in-the-united-states
#4
Jack Cappozzo, Lauren Jackson, Hyun Jung Lee, Wei Zhou, Fadwa Al-Taher, Jerry Zweigenbaum, Dojin Ryu
Ochratoxin A (OTA) is a possible human carcinogen and occurs frequently in cereal grain, soy, and other agricultural commodities. Infants and young children may be more susceptible to contaminants than adults because of their lower body weight, higher metabolic rate, reduced ability to detoxify food toxicants, and more restricted diet. The purpose of this study was to investigate the occurrence and levels of OTA in infant formula and infant cereal products available in the U.S. market. In the present study, 98 powdered infant formula (milk- and soy-based) samples and 155 infant cereal (barley-, rice-, oat-, wheat-, and mixed grain-based) products were collected from different retail locations in the United States over a 2-year period...
February 2017: Journal of Food Protection
https://www.readbyqxmd.com/read/28216565/reply-to-comment-on-screening-and-identification-of-novel-ochratoxin-a-producing-fungi-from-grapes-toxins-2016-8-333-in-reporting-ochratoxin-a-production-from-strains-of-aspergillus-penicillium-and-talaromyces
#5
Xiaoyun Zhang, Yulin Li, Haiying Wang, Xiangyu Gu, Xiangfeng Zheng, Yun Wang, Junwei Diao, Yaping Peng, Hongyin Zhang
n/a.
February 14, 2017: Toxins
https://www.readbyqxmd.com/read/28216564/comments-on-screening-and-identification-of-novel-ochratoxin-a-producing-fungi-from-grapes-toxins-2016-8-333-in-reporting-ochratoxin-a-production-from-strains-of-aspergillus-penicillium-and-talaromyces
#6
Giancarlo Perrone, Antonio F Logrieco, Jens C Frisvad
Recently a species in the genus Talaromyces, a uniseriate species of Aspergillus section Nigri and an isolate each of two widespread species, Penicillium rubens and P. commune, were reported to produce ochratoxin A. This claim was based on insufficient biological and chemical data. We propose a list of criteria that need to be met before an unexpected mycotoxin producer is reported. There have only been convincing data on ochratoxin A production for Penicillium verrucosum, P. nordicum, P. thymicola, all from Penicillium series Verrucosa, and from species in three sections of Aspergillus: section Circumdati, section Nigri and section Flavi...
February 14, 2017: Toxins
https://www.readbyqxmd.com/read/28213222/development-of-a-qcm-d-biosensor-for-ochratoxin-a-detection-in-red-wine
#7
Aleksandra Karczmarczyk, Karsten Haupt, Karl-Heinz Feller
Ochratoxin A (OTA), a highly toxic compound, is one of the most widely spread mycotoxins that contaminates a large variety of agricultural commodities. Due to its presence in the food chain, it imposes a hazard on both human and animal health. Therefore, there is a need for precise, fast and simple methods for toxin quantification. Herein, a novel sensor based on a quartz crystal microbalance with dissipation monitoring (QCM-D) and antibodies for specific analyte recognition was developed for rapid and sensitive detection of OTA in red wine...
May 1, 2017: Talanta
https://www.readbyqxmd.com/read/28208797/multi-mycotoxin%C3%A2-analysis%C3%A2-in%C3%A2-durum%C3%A2-wheat%C3%A2-pasta%C3%A2-by%C3%A2-liquid%C3%A2-chromatography%C3%A2-coupled%C3%A2-to%C3%A2-quadrupole%C3%A2-orbitrap%C3%A2-mass%C3%A2-spectrometry
#8
Josefa Tolosa, Giulia Graziani, Anna Gaspari, Donato Chianese, Emilia Ferrer, Jordi Mañes, Alberto Ritieni
A simple and rapid multi-mycotoxin method for the determination of 17 mycotoxins  simultaneously  is  described  in  the  present  survey  on  durum  and  soft  wheat  pasta  samples.  Mycotoxins included in the study were those mainly reported in cereal samples: ochratoxin-A  (OTA), aflatoxin B1 (AFB1), zearalenone (ZON), deoxynivalenol (DON), 3-and 15-acetyl-deoxynivalenol  (3-AcDON and 15-AcDON), nivalenol (NIV), neosolaniol (NEO), fusarenon-X, (FUS-X), T-2 toxin  (T-2) and HT-2 toxin (HT-2), fumonisin B1 and B2 (FB1 and FB2), and four emerging mycotoxins:  three  enniatins  (ENA,  ENA1,  and  ENB),  and  beauvericin  (BEA)...
February 9, 2017: Toxins
https://www.readbyqxmd.com/read/28208258/tuning-the-aggregation-disaggregation-behavior-of-graphene-quantum-dots-by-structure-switching-aptamer-for-high-sensitivity-fluorescent-ochratoxin-a-sensor
#9
Song Wang, Yajun Zhang, Guangsheng Pang, Yingwei Zhang, Shaojun Guo
The design of graphene quantum dots (GQDs)-aptamer bioconjugates as the new sensing platform is very important for developing high-sensitivity fluorescent biosensors; however, achieving new bioconjugates is still a great challenge. Herein, we report the development of a new high-sensitivity fluorescent aptasensor for the detection of ochratoxin A (OTA) based on tuning aggregation/disaggregation behavior of GQDs by structure-switching aptamers. The fluorescence sensing process for OTA detection involved two key steps: (1) cDNA-aptamer (cDNA, complementary to part of the OTA aptamer) hybridization induced the aggregation of GQD (fluorescence quenching) after cDNA was added into the GQDs-aptamer bioconjugate solution, and (2) the target of OTA triggered disaggregation of GQD aggregates (fluorescence recovery)...
February 7, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/28195330/positive-and-negative-aspects-of-green-coffee-consumption-antioxidant-activity-vs-mycotoxins
#10
Magdalena Jeszka-Skowron, Agnieszka Zgoła-Grześkowiak, Agnieszka Waśkiewicz, Łukasz Stępień, Ewa Stanisz
BACKGROUND: The quality of coffee depends not only on the contents of healthy compounds but also on its contamination with microorganisms which can produce mycotoxins during development, harvesting, preparation, transport and storage. RESULTS: Antioxidant activity of green coffee brews measured in this study by ABTS, DPPH and Folin-Ciocalteu assays showed that coffee extracts from Robusta beans possessed highest activity in all assays than extracts from Arabica coffee...
February 13, 2017: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/28187328/survey-of-penicillia-associated-with-italian-grana-cheese
#11
S Decontardi, A Mauro, N Lima, P Battilani
The present work aimed to contribute information on the mycobiota associated with ripening grana cheese, with focus on the genus Penicillium as potential mycotoxin producers. Eighteen wheels of grana cheese, aged in different storehouses situated in Northern Italy, were sampled to isolate associated fungi. Penicillium spp. were commonly dominant; morphological observation and gene sequencing were applied to identify Penicillium at species level. P. crustosum and P. solitum were the dominant species. Citrinin and ochratoxin A mycotoxins were analysed and the latter was found in all grana cheese samples...
January 31, 2017: International Journal of Food Microbiology
https://www.readbyqxmd.com/read/28145704/ruthenium-nhc-diamine-catalyzed-enantioselective-hydrogenation-of-isocoumarins
#12
Wei Li, Mario P Wiesenfeldt, Frank Glorius
A novel and practical chiral ruthenium-NHC-diamine system is disclosed for the enantioselective hydrogenation of isocoumarins, which provides a new concept to apply (chiral) NHC ligands in asymmetric catalysis. A variety of optically active 3-substituted 3,4-dihydroisocoumarins were obtained in excellent enantioselectivities (up to 99% ee). Moreover, this methodology was utilized in the synthesis of O-methylmellein, mellein, and ochratoxin A.
February 8, 2017: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/28135406/mycotoxin-contamination-of-rice-in-china
#13
REVIEW
Xiang Dong Sun, Ping Su, Hong Shan
Mycotoxin contamination in rice is generally lower than in other cereals such as corn or wheat. However, over 65% of the population in China consumes rice as a staple food. Due to the diversity of the climate across China, the southern region is characterized by high temperatures and humidities, especially in rainy season. Such conditions are optimal for the growth of fungi. The accumulative and transferrable characteristics of fungi mycotoxins pose a great potential threat as confirmed by high incidences of liver cancer in the Yangtze delta region...
January 30, 2017: Journal of Food Science
https://www.readbyqxmd.com/read/28132149/microarray-based-immunoassay-for-parallel-quantification-of-multiple-mycotoxins-in-oat
#14
Susanna Oswald, Richard Dietrich, Erwin Märtlbauer, Reinhard Niessner, Dietmar Knopp
Because multianalyte methods are highly desirable in order to keep analysis time and costs low, the biosensor development increasingly focuses on parallel analysis of several mycotoxins. Here, we describe an indirect competitive immunoassay on regenerable, reusable glass microchips for the parallel determination of aflatoxins, ochratoxin A, deoxynivalenol, and fumonisin B1 in oat extracts, using a fully automated flow-through device with chemiluminescence readout.
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/28130037/assessing-interactions-of-binary-mixtures-of-penicillium-mycotoxins-pms-by-using-a-bovine-macrophage-cell-line-bomacs
#15
Se-Young Oh, Nina Cedergreen, Alexandros Yiannikouris, H V L N Swamy, Niel A Karrow
Penicillium mycotoxins (PMs) are toxic contaminants commonly found as mixtures in animal feed. Therefore, it is important to investigate potential joint toxicity of PM mixtures. In the present study, we assessed the joint effect of binary combinations of the following PMs: citrinin (CIT), ochratoxin A (OTA), patulin (PAT), mycophenolic acid (MPA) and penicillic acid (PA) using independent action (IA) and concentration addition (CA) concepts. Previously published toxicity data (i.e. IC25; PM concentration that inhibited bovine macrophage (BoMacs) proliferation by 25%) were initially analyzed, and both concepts agreed that OTA+PA demonstrated synergism (p<0...
March 1, 2017: Toxicology and Applied Pharmacology
https://www.readbyqxmd.com/read/28112034/ochratoxin-a-and-aflatoxin-b1-in-breakfast-cereals-marketed-in-serbia-occurrence-and-health-risk-characterisation
#16
Ljilja Torović, Ljiljana Trajković Pavlović, Milka Popović
The present paper reports data on the occurrence of ochratoxin A (OTA) and aflatoxin B1 (AFB1) in breakfast cereals marketed in Serbia and interprets consequent dietary exposure. A total of 136 samples was collected in 2012 and 2015 and analysed using high-performance liquid chromatography with fluorescence detection. OTA was detected in 20.7% of the samples in 2012 and 13.0% in 2015, with 3.6% and 0% of the samples above the EU maximum level, respectively. AFB1 was found in low concentrations in 11.1% of the samples collected in 2015, mainly corn based...
February 6, 2017: Food Additives & Contaminants. Part B, Surveillance
https://www.readbyqxmd.com/read/28111348/xenobiotic-transporters-and-kidney-injury
#17
REVIEW
Blessy George, Dahea You, Melanie S Joy, Lauren M Aleksunes
Renal proximal tubules are targets for toxicity due in part to the expression of transporters that mediate the secretion and reabsorption of xenobiotics. Alterations in transporter expression and/or function can enhance the accumulation of toxicants and sensitize the kidneys to injury. This can be observed when xenobiotic uptake by carrier proteins is increased or efflux of toxicants and their metabolites is reduced. Nephrotoxic chemicals include environmental contaminants (halogenated hydrocarbon solvents, the herbicide paraquat, the fungal toxin ochratoxin, and heavy metals) as well as pharmaceuticals (certain beta-lactam antibiotics, antiviral drugs, and chemotherapeutic drugs)...
January 20, 2017: Advanced Drug Delivery Reviews
https://www.readbyqxmd.com/read/28107910/nanobody-based-enzyme-immunoassay-for-ochratoxin-a-in-cereal-with-high-resistance-to-matrix-interference
#18
Xing Liu, Zongwen Tang, Zhenhua Duan, Zhenyun He, Mei Shu, Xianxian Wang, Shirley J Gee, Bruce D Hammock, Yang Xu
A sensitive indirect competitive nanobody-based enzyme linked immunosorbent assay (Nb-ELISA) for ochratoxin A (OTA) with high resistance to cereal matrix interference was developed. Nanobodies against OTA (Nb15, Nb28, Nb32, Nb36) were expressed in E. coli cells and their thermal stabilities were compared with that of an OTA-specific monoclonal antibody 6H8. All nanobodies could still retain their antigen-binding activity after exposure to temperature 95°C for 5min or to 90°C for 75min. Nb28 that exhibited the highest sensitivity in ELISA was selected for further research...
March 1, 2017: Talanta
https://www.readbyqxmd.com/read/28094577/protective-role-of-bentonite-against-aflatoxin-b1-and-ochratoxin-a-induced-immunotoxicity-in-broilers
#19
Sheraz Ahmed Bhatti, Muhammad Zargham Khan, Muhammad Kashif Saleemi, Muhammad Saqib, Ahrar Khan, Zahoor Ul-Hassan
The present study was designed to investigate any ameliorative effects of bentonite (BN) against immuno-pathological alterations induced by dietary aflatoxin B1 (AFB1) or ochratoxin A (OTA) in broiler chicks. In one experiment, AFB1 (0.1, 0.2 or 0.6 mg/kg feed) was fed alone and par alley with bentonite clay (3.7 or 7.5 g/kg feed) to the broilers. In the second experiment, the broilers were given feed contaminated with OTA (0.15, 0.3 or 1.0 mg/kg feed) alone and in combination with bentonite clay (3...
December 2017: Journal of Immunotoxicology
https://www.readbyqxmd.com/read/28089712/effect-of-heme-oxygenase-1-on-ochratoxin-a-induced-nephrotoxicity-in-mice
#20
Agnieszka Loboda, Anna Stachurska, Paulina Podkalicka, Mateusz Sobczak, Olga Mucha, Agnieszka Witalisz-Siepracka, Alicja Jozkowicz, Jozef Dulak
Heme oxygenase-1 (HO-1), a heme-degrading enzyme, is suggested to play an important role in kidney pathophysiology, mostly due to its anti-fibrotic, anti-apoptotic and anti-oxidant properties. One of the mycotoxin, ochratoxin A (OTA) was previously shown to affect HO-1 expression, however, the mechanisms of OTA-induced nephrotoxicity during HO-1 deficiency are unknown. We have shown that OTA regulates the number of pro-fibrotic, pro-inflammatory, anti-oxidative and pro-apoptotic factors in HO-1 dependent manner, as the lack of HO-1 accelerates whereas the induction of HO-1 expression by cobalt protoporphyrin (CoPP) attenuates nephrotoxic effect of OTA...
January 9, 2017: International Journal of Biochemistry & Cell Biology
keyword
keyword
44427
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"