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https://www.readbyqxmd.com/read/29779179/clinical-outcomes-of-complete-revascularization-using-either-angiography-guided-or-fractional-flow-reserve-guided-drug-eluting-stent-implantation-in-non-culprit-vessels-in-st-elevation-myocardial-infarction-patients-insights-from-a-study-based-on-a-systematic
#1
REVIEW
Alexandre Hideo-Kajita, Hector M Garcia-Garcia, Kayode O Kuku, Solomon S Beyene, Viana Azizi, Yael F Meirovich, Gebremedhin D Melaku, Aaphtaab Dheendsa, Echo J Brathwaite, Sameer Desale, Mohammad Soud, Kazuhiro Dan, Yuichi Ozaki, Ron Waksman, Michael Lipinski
Current guidelines recommend that percutaneous coronary intervention (PCI) should be restricted to the culprit vessel in ST elevation myocardial infarction (STEMI) patients with multi-vessel disease (MVD) and without cardiogenic shock. However, newer data suggests that performing complete revascularization (CR) in MVD patients may lead to better outcomes compared to intervention in the culprit vessel only. The aim of this meta-analysis is to examine the available data to determine if CR (using either angio- or fractional flow reserve guidance-FFR) following primary PCI in STEMI patients without cardiogenic shock impacts clinical outcomes...
May 19, 2018: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/29773881/evaluation-of-vascular-changes-with-optical-coherence-tomography-angiography-after-ruthenium-106-brachytherapy-of-circumscribed-choroidal-hemangioma
#2
Gilda Cennamo, Claudia Rossi, Maria Angelica Breve, Nunzio Velotti, Antonio Farella, Raffaele Liuzzi, Giovanni Cennamo
PURPOSE: To describe the vascular changes of circumscribed choroidal hemangioma (CCH) after ruthenium-106 brachytherapy using optical coherence tomography angiography (angio-OCT). METHODS: Seven eyes of 7 patients diagnosed with symptomatic CCH who underwent ruthenium-106 plaque radiotherapy were included in the study. Patients underwent complete ophthalmic examination, bulbar echography and angio-OCT. The same protocol was applied 1 year after ruthenium-106 brachytherapy...
May 18, 2018: Eye
https://www.readbyqxmd.com/read/29769603/components-of-a-new-gene-family-of-ferroxidases-involved-in-virulence-are-functionally-specialized-in-fungal-dimorphism
#3
María Isabel Navarro-Mendoza, Carlos Pérez-Arques, Laura Murcia, Pablo Martínez-García, Carlos Lax, Marta Sanchis, Javier Capilla, Francisco E Nicolás, Victoriano Garre
Mucormycosis is an emerging angio-invasive infection caused by Mucorales that presents unacceptable mortality rates. Iron uptake has been related to mucormycosis, since serum iron availability predisposes the host to suffer this infection. In addition, iron uptake has been described as a limiting factor that determines virulence in other fungal infections, becoming a promising field to study virulence in Mucorales. Here, we identified a gene family of three ferroxidases in Mucor circinelloides, fet3a, fet3b and fet3c, which are overexpressed during infection in a mouse model for mucormycosis, and their expression in vitro is regulated by the availability of iron in the culture media and the dimorphic state...
May 16, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29753139/a-review-on-fabricating-tissue-scaffolds-using-vat-photopolymerization
#4
REVIEW
Nicholas A Chartrain, Christopher B Williams, Abby R Whittington
Vat Photopolymerization (stereolithography, SLA), an Additive Manufacturing (AM) or 3D printing technology, holds particular promise for the fabrication of tissue scaffolds for use in regenerative medicine. Unlike traditional tissue scaffold fabrication techniques, SLA is capable of fabricating designed scaffolds through the selective photopolymerization of a photopolymer resin on the micron scale. SLA offers unprecedented control over scaffold porosity and permeability, as well as pore size, shape, and interconnectivity...
May 9, 2018: Acta Biomaterialia
https://www.readbyqxmd.com/read/29744732/central-venous-access-port-placement-by-translumbar-approach-using-angio-ct-unit-in-patients-with-superior-vena-cava-syndrome
#5
Shuji Kariya, Miyuki Nakatani, Takuji Maruyama, Yasuyuki Ono, Yutaka Ueno, Atsushi Komemushi, Noboru Tanigawa
PURPOSE: To evaluate the clinical results of central venous access port (CV port) placement by translumbar inferior vena cava cannulation using angio-CT unit for cancer patients with superior vena cava syndrome. MATERIALS AND METHODS: A CV port was placed by translumbar inferior vena cava cannulation using an angio-CT unit, in 14 consecutive patients. All patients had occlusion or advanced stenosis of the superior vena cava due to cancer progression. RESULTS: The technical success rate of the percutaneous translumbar CV port placement was 100%...
May 9, 2018: Japanese Journal of Radiology
https://www.readbyqxmd.com/read/29735820/-fusarium-the-versatile-pathogen
#6
REVIEW
Ananya Tupaki-Sreepurna, Anupma Jyoti Kindo
Fusarium is an emerging human opportunistic pathogen of growing importance, especially among immunosuppressed haematology patients due to an increased incidence of disseminated infections over the past two decades. This trend is expected only to continue due to the advances in medical and surgical technologies that will prolong the lives of the severely ill, making these patients susceptible to rare opportunistic infections. Production of mycotoxins, enzymes such as proteases, angio-invasive property and an intrinsically resistant nature, makes this genus very difficult to treat...
January 2018: Indian Journal of Medical Microbiology
https://www.readbyqxmd.com/read/29713819/evaluation-of-the-risk-factors-for-ventricular-arrhythmias-secondary-to-qt-prolongation-induced-by-papaverine-injection-during-coronary-flow-reserve-studies-using-a-4-fr-angio-catheter
#7
Yoshitaka Okabe, Kanichi Otowa, Yasuhito Mitamura, Hisayoshi Murai, Soichiro Usui, Shuichi Kaneko, Masayuki Takamura
Estimation of the fractional flow reserve (FFR) is considered to be an established method by which to assess stable coronary artery stenosis. Induction of maximal coronary hyperemia is important during the FFR procedure. Papaverine has been reported to increase the risk of ventricular arrhythmia (VA). The purpose of the present study was to discover predictors of papaverine-induced VAs developing during FFR measurement. A total of 213 clinically stable patients were included in the study. FFRs were determined after intracoronary papaverine administration (12 mg into the left and 8 mg into the right coronary arteries)...
April 30, 2018: Heart and Vessels
https://www.readbyqxmd.com/read/29706477/usefulness-of-the-finet-law-to-guide-stent-size-selection-in-ostial-left-main-stenting-comparison-with-standard-angiographic-estimation
#8
Gianluca Rigatelli, Marco Zuin, Federico Ronco, Francesco Caprioglio, Daniele Cavazzini, Sara Giatti, Gabriele Braggion, Stefano Perilli, Van Tan Nguyen
BACKGROUNDS: Intravascular ultrasound has been suggested to optimize stent diameter and length in Left Main (LM) procedures, but in the real-world ostial LM stenting is often accomplished with angiography only guidance. The Finet law which regulates the fractal geometry of human bifurcation has the potential to increase the accuracy of stent-sizing. To retrospectively evaluating the impact on outcomes of the addition of Finet Law to standard quantitative coronary angiography (QCA) in guiding stent selection of ostial LM stenting compared to standard angiography estimation...
April 10, 2018: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/29704959/associated-arterial-and-venous-cerebral-manifestations-in-beh%C3%A3-et-s-disease
#9
C Brenière, C Blanc, H Devilliers, M Samson, B Delpont, P Bielefeld, J-F Besancenot, M Giroud, Y Béjot
Behçet's disease is a rare multisystemic vasculitis with an etiology that is still unknown. Neurological manifestations may be seen in approximately 5-15% of patients, and both parenchymal and extraparenchymal neurological involvement has been described. When cerebral venous thrombosis (CVT) is the main extraparenchymal manifestation of Behçet's disease, the condition is then dubbed "angio-Behçet's syndrome". However, arterial involvement is extremely rare, with only one reported case of vasculo-neuro-Behçet's disease, characterized by both venous and intracranial arterial involvement - until now...
April 25, 2018: Revue Neurologique
https://www.readbyqxmd.com/read/29701401/endovascular-treatment-of-proper-hepatic-artery-aneurysm-case-report
#10
Tiago Soares, Ricardo Castro-Ferreira, Marina Neto, João Rocha Neves, José Pedro Pinto, Joel Sousa, Luis Gamas, Paulo Dias, Sérgio Sampaio, José Fernando Teixeira
INTRODUCTION: Hepatic artery aneurysms (HAAs) are rare, representing about 0.1-2% of all arterial aneurysms. They are the second most common splanchnic aneurysms, after splenic artery aneurysms. They have the highest rate of rupture among all splanchnic artery aneurysms and frequently become symptomatic. METHODS: To present a case of a hepatic artery aneurysm treated by endovascular technique. RESULTS: A 65-year old man who had a medical history of hypertension, dyslipidemia and smoking, with an incidental finding on a CT imaging of a hepatic artery aneurysm (maximum diameter 75mm) was admitted for selective arteriography and treatment...
July 2017: Revista Portuguesa de Cirurgia Cardio-torácica e Vascular
https://www.readbyqxmd.com/read/29701346/endovascular-solutions-for-thoracic-aortic-aneurysms-with-challenging-anatomies
#11
José Oliveira-Pinto, Joel Sousa, João Rocha-Neves, Emilio Silva, Vincent Riambau, José Teixeira
INTRODUCTION: The suitability of the proximal and distal landing zones remains one of the main limitations to thoracic endovascular aortic repair. The advent of custom-made scalloped stent grafts widened the endovascular options in some challenging anatomies. METHODS: The authors present three cases of thoracic aortic aneurysm (TAA), with three different hostile anatomies, successfully treated with custom-made scalloped stent grafts. RESULTS: Case1: Male patient, 47 years old, no relevant medical history...
July 2017: Revista Portuguesa de Cirurgia Cardio-torácica e Vascular
https://www.readbyqxmd.com/read/29691683/angio-3-a-10-residue-peptide-derived-from-human-plasminogen-kringle-3-suppresses-tumor-growth-in-mice-via-impeding-both-angiogenesis-and-vascular-permeability
#12
Shruthi Venugopal, Chieh Kao, Ritu Chandna, Konerirajapuram N Sulochana, Vivekanandan Subramanian, Mo Chen, R Manjunatha Kini, Ruowen Ge
Anti-angiogenesis therapy is an established therapeutic strategy for cancer. The endogenous angiogenic inhibitor angiostatin contains the first 3-4 kringle domains of plasminogen and inhibits both angiogenesis and vascular permeability. We present here a 10-residue peptide, Angio-3, derived from plasminogen kringle 3, which retains the functions of angiostatin in inhibiting both angiogenesis and vascular permeability. NMR studies indicate that Angio-3 holds a solution structure similar to the corresponding region of kringle 3...
April 24, 2018: Angiogenesis
https://www.readbyqxmd.com/read/29687742/amniotic-membrane-and-its-epithelial-and-mesenchymal-stem-cells-as-an-appropriate-source-for-skin-tissue-engineering-and-regenerative-medicine
#13
Behrouz Farhadihosseinabadi, Mehrdad Farahani, Tahereh Tayebi, Ameneh Jafari, Felor Biniazan, Khashayar Modaresifar, Hamideh Moravvej, Soheyl Bahrami, Heinz Redl, Lobat Tayebi, Hassan Niknejad
One of the main goals of tissue engineering and regenerative medicine is to develop skin substitutes for treating deep dermal and full thickness wounds. In this regard, both scaffold and cell source have a fundamental role to achieve exactly the same histological and physiological analog of skin. Amnion epithelial and mesenchymal cells possess the characteristics of pluripotent stem cells which have the capability to differentiate into all three germ layers and can be obtained without any ethical concern. Amniotic cells also produce different growth factors, angio-modulatory cytokines, anti-bacterial peptides and a wide range of anti-inflammatory agents which eventually cause acceleration in wound healing...
April 24, 2018: Artificial Cells, Nanomedicine, and Biotechnology
https://www.readbyqxmd.com/read/29686661/molecular-imaging-of-invasive-pulmonary-aspergillosis-using-immunopet-mri-the-future-looks-bright
#14
REVIEW
Christopher R Thornton
Invasive pulmonary aspergillosis (IPA) is a life-threatening lung disease of immuno-compromised humans caused by the ubiquitous environmental mold Aspergillus . Biomarker tests for the disease lack sensitivity and specificity, and culture of the fungus from invasive lung biopsy is slow, insensitive, and undesirable in critically ill patients. A computed tomogram (CT) of the chest offers a simple non-intrusive diagnostic procedure for rapid decision making, and so is used in many hematology units to drive antifungal treatment...
2018: Frontiers in Microbiology
https://www.readbyqxmd.com/read/29680517/a-study-of-difference-in-serum-25-hydroxyvitamin-d-concentrations-in-patients-with-angiographically-defined-coronary-disease-and-healthy-subjects
#15
Haleh Rokni, Mohsen Moohebati, Maryam Saberi-Karimian, Seyed Reza Mirhafez, Hamideh Ghazizadeh, Atieh Laal-Vazifeh, Maryam Shekari, Faezeh Movahhedianfar, Mohsen Mazidi, Shokoufeh Bonakdaran, Gordon A Ferns, Majid Ghayour-Mobarhan
BACKGROUND: Cardiovascular disease (CVD) is one of the most important causes of death in developing countries. The current study evaluates the serum 25-hydroxyvitamin D (25OHD), phosphate and calcium levels in patients with angiographically-defined coronary artery disease (CAD) and healthy subjects in a sample population in northeastern Iran. METHODS: There were 566 subjects aged between 20-80 years out of whom283 subjects with CAD were divided into two study groups based on their angiogram results; those with > 50% stenosis of one or more coronary arteries and those with ≤ 50% stenosis...
April 12, 2018: Diabetes & Metabolic Syndrome
https://www.readbyqxmd.com/read/29670362/antiangiogenic-effects-of-aa-pme-on-huvecs-in-vitro-and-zebrafish-in-vivo
#16
Yue Jing, Gang Wang, Qi Xiao, Yachun Zhou, Yingjie Wei, Zhunan Gong
Angiogenesis plays a vital role in many physiological and pathological processes and several diseases are connected with its dysregulation. Asiatic acid (AA) has demonstrated anticancer properties and we suspect this might be attributable to an effect on angio-genesis. A modified derivative of AA, N-(2α,3β,23-acetoxyurs-12-en-28-oyl)-L-proline methyl ester (AA-PMe), has improved efficacy over its parent compound, but its effect on blood vessel development remains unclear. Methods: In this study, we investigated the antiangiogenic activity of AA and AA-PMe in zebrafish embryos and human umbilical vein endothelial cells (HUVECs)...
2018: OncoTargets and Therapy
https://www.readbyqxmd.com/read/29663146/thoraco-lumbar-fractures-with-blunt-traumatic-aortic-injury-in-adult-patients-correlations-and-management
#17
Giorgio Santoro, Alessandro Ramieri, Vito Chiarella, Massimo Vigliotta, Maurizio Domenicucci
PURPOSE: Traumatic thoraco-lumbar spine fracture spine with a concomitant blunt aortic injury is uncommon but potentially a fatal association. Our aim was to clarify: morphology of spinal fractures related to vascular damages and vice versa, diagnostic procedures and decision-making process for the best treatment options for spine and vessels. METHODS: We enrolled 42 cases culled from the literature and five personal ones, reviewing in detail by AO Spine Classification, Society of Vascular Surgery classification and Abbreviated Injury Scale for neurological evaluation...
April 16, 2018: European Spine Journal
https://www.readbyqxmd.com/read/29660065/in-reply-angio-architectural-features-of-high-grade-intracranial-dural-arteriovenous-fistulas-correlation-with-aggressive-clinical-presentation-and-hemorrhagic-risk
#18
https://www.readbyqxmd.com/read/29660030/letter-angio-architectural-features-of-high-grade-intracranial-dural-arteriovenous-fistulas-correlation-with-aggressive-clinical-presentation-and-hemorrhagic-risk
#19
Sandra A Cornelissen, Leonard L L Yeo, Michael Söderman
No abstract text is available yet for this article.
April 11, 2018: Neurosurgery
https://www.readbyqxmd.com/read/29659744/human-adipose-mesenchymal-stem-cells-overexpressing-dual-chemotactic-gene-showed-enhanced-angiogenic-capacity-in-ischemic-hindlimb-model
#20
Younggeul Min, Seongho Han, Hyun Aae Ryu, Sung-Whan Kim
Aims: In present study, we sought to characterize the angio-vasculogenic property of human adipose mesenchymal stem cells (ASCs) overexpressing dual chemokine GCP-2 and SDF-1α (ASC-G/S) and to determine the therapeutic potential of ASC-G/S in the context of experimental ischemia. Methods and results: We generated ASC-G/S line and performed flow cytometry, quantitative (q)-PCR, Matrigel tube formation, Matrigel plug assays and in vivo therapeutic assays using hind limb ischemia mouse model...
April 5, 2018: Cardiovascular Research
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