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https://www.readbyqxmd.com/read/28048542/we-ab-bra-06-4dct-ventilation-a-novel-imaging-modality-for-thoracic-surgical-evaluation
#1
Y Vinogradskiy, M Jackson, L Schubert, B Jones, R Castillo, E Castillo, T Guerrero, J Mitchell, B Kavanagh, M Miften
PURPOSE: The current standard-of-care imaging used to evaluate lung cancer patients for surgical resection is nuclear-medicine ventilation. Surgeons use nuclear-medicine images along with pulmonary function tests (PFT) to calculate percent predicted postoperative (%PPO) PFT values by estimating the amount of functioning lung that would be lost with surgery. 4DCT-ventilation is an emerging imaging modality developed in radiation oncology that uses 4DCT data to calculate lung ventilation maps...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047744/we-a-201-01-memorial-introduction
#2
C Marshall
: Chris Marshall: Memorial Introduction Donald Edmonds Herbert Jr., or Don to his colleagues and friends, exemplified the "big tent" vision of medical physics, specializing in Applied Statistics and Dynamical Systems theory. He saw, more clearly than most, that "Making models is the difference between doing science and just fooling around [ref Woodworth, 2004]". Don developed an interest in chemistry at school by "reading a book" - a recurring theme in his story. He was awarded a Westinghouse Science scholarship and attended the Carnegie Institute of Technology (later Carnegie Mellon University) where his interest turned to physics and led to a BS in Physics after transfer to Northwestern University...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047091/we-a-201-02-modern-statistical-modeling
#3
A Niemierko
: Chris Marshall: Memorial Introduction Donald Edmonds Herbert Jr., or Don to his colleagues and friends, exemplified the "big tent" vision of medical physics, specializing in Applied Statistics and Dynamical Systems theory. He saw, more clearly than most, that "Making models is the difference between doing science and just fooling around [ref Woodworth, 2004]". Don developed an interest in chemistry at school by "reading a book" - a recurring theme in his story. He was awarded a Westinghouse Science scholarship and attended the Carnegie Institute of Technology (later Carnegie Mellon University) where his interest turned to physics and led to a BS in Physics after transfer to Northwestern University...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28046561/we-a-201-00-anne-and-donald-herbert-distinguished-lectureship-on-modern-statistical-modeling
#4
Joseph Deasy
: Chris Marshall: Memorial Introduction Donald Edmonds Herbert Jr., or Don to his colleagues and friends, exemplified the "big tent" vision of medical physics, specializing in Applied Statistics and Dynamical Systems theory. He saw, more clearly than most, that "Making models is the difference between doing science and just fooling around [ref Woodworth, 2004]". Don developed an interest in chemistry at school by "reading a book" - a recurring theme in his story. He was awarded a Westinghouse Science scholarship and attended the Carnegie Institute of Technology (later Carnegie Mellon University) where his interest turned to physics and led to a BS in Physics after transfer to Northwestern University...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28040598/radiolabeled-bombesin-derivatives-for-preclinical-oncological-imaging
#5
REVIEW
Carolina de Aguiar Ferreira, Leonardo Lima Fuscaldi, Danyelle M Townsend, Domenico Rubello, André Luís Branco de Barros
Despite efforts, cancer is still one of the leading causes of morbidity and mortality worldwide, with approximately 14 million new cases and 8.2 million cancer-related deaths each year, according to the World Health Organization. Among the strategies to reduce cancer progression and improving its management, implementing early detection technologies is crucial. Based on the fact that several types of cancer cells overexpress surface receptors, small molecule ligands, such as peptides, have been developed to allow tumor identification at earlier stages...
December 29, 2016: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28040092/global-access-to-radiotherapy-in-low-and-middle-income-countries
#6
M Abdel-Wahab, E Fidarova, A Polo
Over the last 60 years, the International Atomic Energy Agency (IAEA) has been working to introduce, expand and improve radiotherapy services, working with partners such as the World Health Organization (WHO) to improve cancer diagnosis, treatment, care and control through collective action in low- and middle-income countries (LMICs). The Lancet Oncology Commission on radiotherapy published a report that defined five calls for action to expand global access to radiotherapy, drawing on the previous work of the Global Taskforce on Radiotherapy for Cancer Control...
February 2017: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/27981732/clinical-impact-of-68-ga-psma-pet-ct-in-prostate-cancer-patients-with-rising-psa-after-treatment-with-curative-intent-preliminary-analysis-of-a-multidisciplinary-approach
#7
S Albisinni, C Artigas, F Aoun, I Biaou, J Grosman, T Gil, E Hawaux, K Limani, F Otte, A Peltier, S Sideris, N Sirtaine, P Flamen, R van Velthoven
BACKGROUND: To assess the impact of (68) Ga-(HBED-CC)-PSMA (Prostate Specific Membrane Antigen) PET/CT in the clinical management of PCa patients with rising PSA after treatment with curative intent. (68) Ga-PSMA PET/CT scan is a novel molecular imaging technique in the field of prostate cancer (PCa). METHODS: 131 consecutive patients were referred to our center for a (68) Ga-PSMA PET/CT in the setting of recurring prostate cancer. 11/131(8%) presented persistent PSA after radical prostatectomy, while 120/131 (92%) were referred for biochemical recurrence after surgery, radiotherapy or both...
December 15, 2016: BJU International
https://www.readbyqxmd.com/read/27928786/-implementation-of-multidisciplinary-team-in-the-diagnosis-and-treatment-of-gastroenteropancreatic-neuroendocrine-neoplasm
#8
Panpan Zhang, Lin Shen
Multidisciplinary team(MDT) has been considered as the best practice in the treatment planning and care for patients with cancer around the world. With the increased range and number of specialists involved, multidisciplinary coordination and communication have been enhanced, and the efficiency and quality of diagnosis and treatment of cancer have been improved. Neuroendocrine neoplasm (NEN) is a heterogeneous group of tumors originating from neuroendocrine cells located throughout the body, most of which is gastroenteropancreatic neuroendocrine neoplasm (GEP-NEN)...
November 25, 2016: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/27924964/frequency-of-cyp2d6-10-genotypes-in-pakistani-breast-cancer-patients-taking-adjuvant-tamoxifen
#9
Nusrat Nazir, Akbar Waheed, Kulsoom Farhat, Muhammad Ismail, Qaisar Mansoor
OBJECTIVE: To investigate the frequency of cytochrome P2D6*10 in breast cancer patients. METHODS: This retrospective study was conducted at the Nuclear Medicine, Oncology and Radiotherapy Institute, Islamabad, and the Combined Military Hospital, Rawalpindi, Pakistan, and comprised medical records of breast cancer patients from January 2000 to September 2013. Pre- and post-menopausal women with diagnosed breast cancer who were advised 20mg/day of tamoxifen as adjuvant therapy were included...
December 2016: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/27906859/recent-advances-in-nuclear-medicine-in-endocrine-oncology
#10
Markus Luster, Andreas Pfestroff, Frederik A Verburg
PURPOSE OF REVIEW: The purpose is to review recent advances concerning the role of nuclear medicine in endocrine oncology. RECENT FINDINGS: For I therapy of thyroid cancer a thyrotropin (TSH) more than 30 mU/l has for many years been deemed a condition sine qua non. However, new data show that patients with lower TSH levels at the time of ablation have the same rate of successful ablation as those with TSH more than 30 mU/l.I-124 combined integrated positron emission tomography and computed X-ray tomography was shown to be highly accurate in predicting findings on posttherapy radioiodine scanning and was shown to have a high prognostic power...
January 2017: Current Opinion in Oncology
https://www.readbyqxmd.com/read/27756360/how-we-read-oncologic-fdg-pet-ct
#11
REVIEW
Michael S Hofman, Rodney J Hicks
(18)F-fluorodeoxyglucose (FDG) PET/CT is a pivotal imaging modality for cancer imaging, assisting diagnosis, staging of patients with newly diagnosed malignancy, restaging following therapy and surveillance. Interpretation requires integration of the metabolic and anatomic findings provided by the PET and CT components which transcend the knowledge base isolated in the worlds of nuclear medicine and radiology, respectively. In the manuscript we detail our approach to reviewing and reporting a PET/CT study using the most commonly used radiotracer, FDG...
October 18, 2016: Cancer Imaging: the Official Publication of the International Cancer Imaging Society
https://www.readbyqxmd.com/read/27752508/prevalence-of-depression-and-anxiety-amongst-cancer-patients-in-a-hospital-setting-a-cross-sectional-study
#12
Anish Khalil, Muhammad Faheem, Ammad Fahim, Haran Innocent, Zainab Mansoor, Shehrbano Rizvi, Hizra Farrukh
Background. The biomedical care for cancer has not been complemented by psychosocial progressions in cancer care. Objectives. To find the prevalence of anxiety and depression amongst cancer patients in a hospital setting. Design and Setting. This cross-sectional study was conducted at the tertiary care hospitals Shifa International Hospital Islamabad and Nuclear Medicine, Oncology, and Radiotherapy Institute [NORI]. Patients and Methods. 300 patients were interviewed from both the outpatient and inpatient department using The Aga Khan University Anxiety and Depression Scale (AKUADS)...
2016: Psychiatry Journal
https://www.readbyqxmd.com/read/27694179/prostate-specific-membrane-antigen-targeted-radiohalogenated-pet-and-therapeutic-agents-for-prostate-cancer
#13
Steven P Rowe, Alexander Drzezga, Bernd Neumaier, Markus Dietlein, Michael A Gorin, Michael R Zalutsky, Martin G Pomper
Radiohalogenated agents are often the first line of pursuit in the development of new radiopharmaceuticals-whether antibodies, peptides, or small molecules-because of their ease of synthesis, lack of substantial steric perturbation of the original affinity agent (in some cases, providing enhanced affinity), and capacity to be transformed into therapeutics (in some cases, with a mere switch of an isotope). They often provide proof of a principle before optimization for pharmacokinetics or generation of radiometallated agents, when the latter are necessary...
October 2016: Journal of Nuclear Medicine: Official Publication, Society of Nuclear Medicine
https://www.readbyqxmd.com/read/27607175/recommendations-and-technical-aspects-of-16%C3%AE-18f-fluoro-17%C3%AE-estradiol-pet-to-image-the-estrogen-receptor-in-vivo-the-groningen-experience
#14
REVIEW
Clasina M Venema, Giulia Apollonio, Geke A P Hospers, Carolina P Schröder, Rudi A J O Dierckx, Erik F J de Vries, Andor W J M Glaudemans
The estrogen derivative 16α-F-fluoro-17β-estradiol (FES) is a PET tracer that has been used in a variety of preclinical and clinical studies to detect estrogen receptor (ER) expression, mainly in breast cancer, but also for other oncological indications. As a result of the success of these studies and the potential applications of the tracer, FES starts to be implemented in routine clinical practice. However, the number of centers using this tracer is still limited and many nuclear medicine physicians and medical oncologists are still unaware of the possibilities FES PET imaging offers...
November 2016: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/27601958/the-contribution-of-women-to-radiobiology-marie-curie-and-beyond
#15
REVIEW
Anna Gasinska
Marie Sklodowska-Curie, an extraordinary woman, a Polish scientist who lived and worked in France, led to the development of nuclear energy and the treatment of cancer. She was the laureate of two Nobel Prizes, the first woman in Europe who obtained the degree of Doctor of Science and opened the way for women to enter fields which had been previously reserved for men only. As a result of her determination and her love of freedom, she has become an icon for many female scientists active in radiation sciences...
May 2016: Reports of Practical Oncology and Radiotherapy
https://www.readbyqxmd.com/read/27554357/protein-protein-interaction-inhibitors-advances-in-anticancer-drug-design
#16
Leonardo G Ferreira, Glaucius Oliva, Adriano D Andricopulo
INTRODUCTION: Pocket-based drug design has contributed to major scientific breakthroughs in pharmaceutical research and development (R&D). The integrated use of experimental and computational methods, primarily during the early phases of drug discovery, has enabled the development of highly potent and selective small-molecule ligands. In this scenario, the targeting of protein-protein interactions (PPIs) has emerged as an attractive strategy for designing innovative drugs for highly complex diseases, such as cancer...
October 2016: Expert Opinion on Drug Discovery
https://www.readbyqxmd.com/read/27523813/contrast-enhanced-ct-and-mri-based-perfusion-assessment-for-pulmonary-diseases-basics-and-clinical-applications
#17
Yoshiharu Ohno, Hisanobu Koyama, Ho Yun Lee, Sachiko Miura, Takeshi Yoshikawa, Kazuro Sugimura
Assessment of regional pulmonary perfusion as well as nodule and tumor perfusions in various pulmonary diseases are currently performed by means of nuclear medicine studies requiring radioactive macroaggregates, dual-energy computed tomography (CT), and dynamic first-pass contrast-enhanced perfusion CT techniques and unenhanced and dynamic first-pass contrast enhanced perfusion magnetic resonance imaging (MRI), as well as time-resolved three-dimensional or four-dimensional contrast-enhanced magnetic resonance angiography (MRA)...
September 2016: Diagnostic and Interventional Radiology: Official Journal of the Turkish Society of Radiology
https://www.readbyqxmd.com/read/27498771/-corrigendum-vegf-in-nuclear-medicine-clinical-application-in-cancer-and-future-perspectives-review
#18
Samanta Taurone, Filippo Galli, Alberto Signore, Enzo Agostinelli, Rudi A J O Dierckx, Antonio Minni, Marcella Pucci, Marco Artico
Following the publication of this article, after having re-examined our manuscript, we noted an error in the acknowledgements section, as regards the funding of our study. The correct version of acknowledgements section is shown below: Acknowledgements This study was supported by the Ministry of Health and Fondazione Roma and by NOBILE S.p.A. Thanks are also due to REGIONE LAZIO Prot. FILAS-RU-2014 - 1020 (E.A.). [the original article was published in the International Journal of Oncology 49: 437-447, 2016; DOI: 10...
October 2016: International Journal of Oncology
https://www.readbyqxmd.com/read/27485215/10-year-experience-regarding-the-reliability-and-morbidity-of-radio-guided-lymph-node-biopsy-in-penile-cancer-patients-and-the-associated-radiation-exposure-of-medical-staff-in-this-procedure
#19
Ulf Lützen, Carsten Maik Naumann, Jens Dischinger, Marlies Marx, René Baumann, Yi Zhao, Michael Jüptner, Daniar Osmonov, Katrin Bothe, Klaus-Peter Jünemann, Maaz Zuhayra
BACKGROUND: The guidelines of the European Association of Urologists (EAU), of the German Society of Nuclear Medicine (DGN), and the European Society for Medical Oncology (ESMO) recommend sentinel lymph node biopsy (SLNB) for lymph node staging in penile cancer with non-palpable inguinal lymph nodes as one diagnostic method. Despite this, the method is neither widely nor regularly applied in Germany - the same applies to many other countries, which may be due to insecurity in dealing with open radioactive tracers...
August 2, 2016: BMC Urology
https://www.readbyqxmd.com/read/27477929/quality-of-life-in-breast-cancer-sufferers
#20
Ahmed Essmat Shouman, Nahla Fawzy Abou El Ezz, Nivine Gado, Amal Mahmoud Ibrahim Goda
Purpose - The purpose of this paper is to measure health-related quality of life (QOL) among patients with early stage cancer breast under curative treatment at department of oncology and nuclear medicine at Ain Shams University Hospitals. Identify factors affecting QOL among these patients. Design/methodology/approach - A cross-sectional study measured QOL among early stage female breast cancer (BC) patients and determined the main factors affecting their QOL. Three interviewer administered questionnaires were used...
August 8, 2016: International Journal of Health Care Quality Assurance
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