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https://www.readbyqxmd.com/read/28550704/integrating-engagement-and-improvement-work-in-a-pediatric-hospital
#1
Mireille Brosseau, Diane Gagnon, Kristina Rohde, Jennifer Schellinck
Although geared towards a common goal - improved patient-centred care - quality improvement strategies and patient engagement-focused approaches are often developed and conducted in silos. The lack of integration may lead, on the one hand, to the uptake of patient suggestions that do not always take into consideration implications for the delivery of quality care and, on the other hand, to inadequate understanding of patient views required to create optimal services. The Children's Hospital of Eastern Ontario (CHEO)'s action plans to address gaps in patient engagement and quality improvement, two of its priority areas, were initially carried out in isolation of each other...
2017: Healthcare Quarterly
https://www.readbyqxmd.com/read/28550606/renal-injury-in-pediatric-anorexia-nervosa-a-retrospective-study
#2
Chantal Stheneur, Sebastien J Bergeron, Jean-Yves Frappier, Olivier Jamoulle, Danielle Taddeo, Marc Sznajder, Anne-Laure Lapeyraque
PURPOSE: Although primarily a mental health disorder, anorexia nervosa (AN) has many physical consequences. Among them, the consequences on kidney function are often underestimated. We evaluated renal function in adolescent AN inpatients and investigated the correlation between the GFR and intrinsic patient characteristics. METHODS: A single-center retrospective study was conducted on 51 patients hospitalized for the restrictive type of AN in 2013. Data were divided into: (1) medical history of AN; (2) growth parameters and vital signs upon admission; and (3) blood tests...
May 26, 2017: Eating and Weight Disorders: EWD
https://www.readbyqxmd.com/read/28550450/abcc4-functional-snp-in-the-3-splice-acceptor-site-of-exon-8-g912t-is-associated-with-unfavorable-clinical-outcome-in-children-with-acute-lymphoblastic-leukemia
#3
Hamzeh Mesrian Tanha, Soheila Rahgozar, Marjan Mojtabavi Naeini
OBJECTIVES: ATP-binding cassette subfamily C member 4 (ABCC4) encoding MRP4 protein is involved in pediatric acute lymphoblastic leukemia (ALL) drug resistance. The nonsynonymous single nucleotide polymorphism (SNP) rs2274407 (G912T; K304N) is located in the 3' splice acceptor site of exon 8 of ABCC4 pre-mRNA. The aim of this study was to investigate the prognostic value of rs2274407 in childhood ALL and its possible functional effect on MRP4. METHODS: ABCC4 G912T SNP was genotyped in 145 Iranian Philadelphia-negative (Ph(-)) children with ALL using modified tetra-primer ARMS PCR and evaluated for possible association with 3-year disease-free survival (3DFS)...
May 26, 2017: Cancer Chemotherapy and Pharmacology
https://www.readbyqxmd.com/read/28550392/treatment-of-pediatric-average-risk-medulloblastoma-using-craniospinal-irradiation-less-than-2500-cgy-and-chemotherapy-single-center-experience-in-korea
#4
Jong Hyung Yoon, Kyung Duk Park, Hyoung Jin Kang, Hyery Kim, Ji Won Lee, Seung-Ki Kim, Kyu-Chang Wang, Sung-Hye Park, Il Han Kim, Hee Young Shin
BACKGROUND: Although craniospinal irradiation (CSI) of 2340 cGy plus tumor booster with chemotherapy have been established as a standard treatment of childhood average-risk (AvR) medulloblastoma (MBL) in Western counties, there are a few recent reports in outcomes of AvR MBL using this strategy in Korean and other Asian children. We investigated the outcome of the Korean children with AvR MBL who were treated with CSI <2500 cGy and chemotherapy. METHODS: Between January 2001 and December 2010, clinical characteristics and outcomes of 42 patients who were diagnosed with AvR MBL postoperatively and treated with radiation including CSI <2500 cGy and chemotherapy in Seoul National University Children's Hospital were analyzed...
May 27, 2017: World Journal of Pediatrics: WJP
https://www.readbyqxmd.com/read/28550366/minimally-invasive-resection-of-adrenal-masses-in-infants-and-children-results-of-a-european-multi-center-survey
#5
Francesco Fascetti-Leon, Giovanni Scotton, Luca Pio, Raimundo Beltrà, Paolo Caione, Ciro Esposito, Girolamo Mattioli, Amulya K Saxena, Sabine Sarnaki, Piergiorgio Gamba
BACKGROUND: Minimal access adrenal surgery (MAAS) for adrenal pathologies is the standard for many pediatric surgical centers. However, the literature offers few reports and minimal evidence from small case series. The aim of this study was to evaluate the outcomes of pediatric MAAS through a multi-center data analysis. METHOD: Pediatric patients who underwent MAAS between January 2002 and December 2013 were retrospectively included. Data analysis was conducted using Spss software (Welch's t-test, X-square, Fisher tests, multiple regression model)...
May 26, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28550357/apparent-diffusion-coefficient-in-differentiation-of-pediatric-posterior-fossa-tumors
#6
Soubhi Zitouni, Gonca Koc, Selim Doganay, Sibel Saracoglu, Kazim Z Gumus, Saliha Ciraci, Abdulhakim Coskun, Ekrem Unal, Huseyin Per, Ali Kurtsoy, Olgun Kontas
PURPOSE: To investigate the contribution of preoperative apparent diffusion coefficient (ADC) values in the differential diagnosis of pediatric posterior fossa tumors. METHODS: Forty-two pediatric patients (mean age 7.76 ± 4.58 years) with intra-axial tumors in the infra-tentorial region underwent magnetic resonance imaging. ADC measurement was performed using regions of interest, obtained from the solid component of the mass lesions. ADC ratios were calculated by dividing the ADC values from the mass lesions by the ADC values from normal cerebellar parenchyma...
May 26, 2017: Japanese Journal of Radiology
https://www.readbyqxmd.com/read/28550349/choice-of-repairing-inguinal-hernia-in-children-open-versus-laparoscopy
#7
Venkatachalam Raveenthiran, Prakash Agarwal
Inguinal hernia is a common disorder of childhood that requires surgical repair at diagnosis. Traditionally, it is operated upon by open inguinal incision. However, with the introduction of laparoscopic repair in 1990, opinion of scientific community is divided concerning the best method of pediatric herniotomy. Educated parents, who long to have the choicest of the best, often gather information from internet and prefer to discuss their concerns with primary care physicians. This descriptive review is intended to provide practicing pediatricians with updated evidence-based information which will enable them to counsel parents regarding the choice of hernia repair...
May 27, 2017: Indian Journal of Pediatrics
https://www.readbyqxmd.com/read/28550188/recommendations-for-splenectomy-in-hereditary-hemolytic-anemias
#8
Achille Iolascon, Immacolata Andolfo, Wilma Barcellini, Francesco Corcione, Loïc Garçon, Lucia De Franceschi, Claudio Pignata, Giovanna Graziadei, Dagmar Pospisilova, David C Rees, Mariane de Montalembert, Stefano Rivella, Antonella Gambale, Roberta Russo, Leticia Ribeiro, Jules Vives-Corrons, Patricia Aguilar-Martinez, Antonis Kattamis, Beatrice Gulbis, Maria Domenica Cappellini, Irene Roberts, Hannah Tamary
Hereditary hemolytic anemias are a group of disorders including red cell membrane defects, red blood cells enzyme disorders, congenital dyserythropoietic anemias, thalassemia syndromes and haemoglobinopathies. As damaged red blood cells passing through the spleen red pulp are efficiently removed by splenic macrophages, splenectomy is one possible therapeutic approach to the management of severely affected patients. However, except for hereditary spherocytosis for which the effectiveness of splenectomy has been well documented, the efficacy of splenectomy in other anemias within this group has yet to be determined and there are concerns regarding short- and long-term infectious and thrombotic complications...
May 26, 2017: Haematologica
https://www.readbyqxmd.com/read/28550026/localized-adult-ewing-sarcoma-favorable-outcomes-with-alternating-vincristine-doxorubicin-cyclophosphamide-and-ifosfamide-etoposide-vdc-ie-based-multimodality-therapy
#9
Jennifer L Pretz, Constance M Barysauskas, Suzanne George, Jason L Hornick, Chandrajit P Raut, Yen-Lin E Chen, Karen J Marcus, Edwin Choy, Francis Hornicek, John E Ready, Thomas F DeLaney, Elizabeth H Baldini
BACKGROUND: In children with localized Ewing sarcoma (ES), addition of ifosfamide and etoposide to cyclophosphamide, doxorubicin, and vincristine (VDC/IE) improved 5-year overall survival (OS) to 70%-80%. Prior to delivery of VDC/IE in adults, 5-year OS was <50%. We reviewed our institutional outcomes for adults with ES who received VDC/IE-based treatment. MATERIALS AND METHODS: Between 1997-2013, 67 adults with localized ES were treated with curative intent...
May 26, 2017: Oncologist
https://www.readbyqxmd.com/read/28549894/diagnosis-and-management-of-dermatofibrosarcoma-protuberans-in-a%C3%A2-3-year-old-patient
#10
Rajiv Iyengar, Elizabeth Kiwanuka, Shamlal Mangray, Antonio P Cruz, Julia Katarincic, Reena Bhatt
In this case report, we present a 3-year-old boy with a diagnosis of dermatofibrosarcoma protuberans (DFSP) on the dorsum of his right hand. Although rarely metastatic, DFSP is highly locally invasive and can cause considerable local morbidity. In the hand, DFSP is uncommon in the young pediatric patient. In our patient, the tumor extended down to the second and third metacarpal heads and was treated with a multistaged excision of his tumor to achieve negative margins under slow Mohs micrographic surgery.
May 24, 2017: Journal of Hand Surgery
https://www.readbyqxmd.com/read/28549858/a-prospective-observational-cohort-study-to-assess-the-incidence-of-acute-otitis-media-among-children-0-5-years-of-age-in-southern-brazil
#11
Tatiana M Lanzieri, Clóvis Arns da Cunha, Rejane B Cunha, D Fermin Arguello, Raghavendra Devadiga, Nervo Sanchez, Eduardo Ortega Barria
OBJECTIVES: To estimate acute otitis media (AOM) incidence among young children and impact on quality of life of parents/caregivers in a southern Brazilian city. METHODS: Prospective cohort study including children 0-5 years of age registered at a private pediatric practice. AOM episodes diagnosed by a pediatrician and impact on quality of life of parents/caregivers were assessed during a 12-month follow-up. RESULTS: During September 2008-March 2010, of 1136 children enrolled in the study, 1074 (95%) were followed: 55...
May 23, 2017: Brazilian Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28549751/prader-willi-syndrome-101-an-overview-for-pediatric-nurses
#12
Kathryn Anglin
No abstract text is available yet for this article.
May 23, 2017: Journal of Pediatric Nursing
https://www.readbyqxmd.com/read/28549726/spasticity-dyskinesia-and-ataxia-in-cerebral-palsy-are-we-sure-we-can-differentiate-them
#13
H Eggink, D Kremer, O F Brouwer, M F Contarino, M E van Egmond, A Elema, K Folmer, J F van Hoorn, L A van de Pol, V Roelfsema, M A J Tijssen
OBJECTIVE: Cerebral palsy (CP) can be classified as spastic, dyskinetic, ataxic or combined. Correct classification is essential for symptom-targeted treatment. This study aimed to investigate agreement among professionals on the phenotype of children with CP based on standardized videos. METHODS: In a prospective, observational pilot study, videos of fifteen CP patients (8 boys, mean age 11 ± 5 y) were rated by three pediatric neurologists, three rehabilitation physicians and three movement disorder specialists...
May 9, 2017: European Journal of Paediatric Neurology: EJPN
https://www.readbyqxmd.com/read/28549686/pilonidal-sinus-disease-surgery-in-children-the-first-study-to-compare-crystallized-phenol-application-to-primary-excision-and-closure
#14
Ufuk Ates, Ergun Ergun, Gulnur Gollu, Sumeyye Sozduyar, Meltem Kologlu, Murat Cakmak, Huseyin Dindar, Aydin Yagmurlu
INTRODUCTION: Pilonidal sinus (PS) is an infectious and inflammatory disease of sacrococcygeal region. Current methods include; surgical excision with/without suturing the defect, rhomboid excision and flap and chemical substance application. In this study, crystallized phenol application was compared to excision and primary closure. PATIENTS AND METHODS: This retrospective study included pediatric patients with PS who were treated with excision and primer closure technique and phenol application...
May 16, 2017: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/28549684/primary-laparoscopic-gastrojejunostomy-tubes-as-a-feeding-modality-in-the-pediatric-population
#15
Chinwendu Onwubiko, Brent R Weil, Sigrid Bairdain, Amber M Hall, Julia M Perkins, Hariharan Thangarajah, Maireade E McSweeney, C Jason Smithers
PURPOSE: Outcomes associated with primary laparoscopic gastrojejunal (GJ) tube placement in the pediatric population were evaluated. METHODS: A single-institution, retrospective review examined patients undergoing laparoscopic GJ tube placement between June 2011 and December 2014. Outcomes included gastric feeding tolerance, subsequent fundoplication, complications, and mortality. RESULTS: Ninety laparoscopic GJ tubes were placed. Median follow-up was 342days (interquartile range [IQR]=141-561days)...
May 20, 2017: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/28549669/the-iscreen-electronic-diabetes-dashboard-a-tool-to-improve-knowledge-and-implementation-of-clinical-practice-guidelines
#16
Stacy Zahanova, Alexandra Tsouka, Mark R Palmert, Farid H Mahmud
OBJECTIVES: Clinical practice guidelines (CPG) provide evidence-based recommendations for patient care but may not be optimally applied in clinical settings. As a pilot study, we evaluated the impact of a computerized, point-of-care decision support system (CDSS) on guideline knowledge and adherence in our diabetes clinic. METHODS: iSCREEN, a CDSS, integrated with a province-wide electronic health record, was designed based on the Canadian Diabetes Association 2013 Clinical Practice Guidelines for the Prevention and Management of Diabetes in Canada...
May 23, 2017: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/28549608/current-challenges-with-proximal-hypospadias-we-have-a-long-way-to-go
#17
REVIEW
Edward M Gong, Earl Y Cheng
BACKGROUND AND PURPOSE: Proximal hypospadias repair has continued to challenge the pediatric urologist despite great efforts to develop better techniques for repair. METHODS: In this article, we review the literature regarding modern proximal hypospadias repair approaches and outcomes. We also present our current approach to proximal hypospadias repair surgery and outcome tracking. Finally, we review the literature on surgical outcome tools that may help us standardize research...
April 21, 2017: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/28549578/pediatric-out-of-hospital-cardiac-arrest-caused-by-left-coronary-artery-agenesis-with-primary-shockable-rhythm-a-brief-report
#18
Moritz Weigeldt, Sabine Lahmann, Konstantin Krieger, Sebastian Buttenberg, Volker Stephan, Brigitte Stiller, Dirk Stengel
BACKGROUND: To illustrate a rare cause of out-of-hospital cardiac arrest in children, its differential diagnoses, emergency and subsequent treatment at various steps in the rescue chain, and potential outcomes. CASE PRESENTATION: A 4-year-old boy with unknown agenesis of the left coronary ostium sustained out-of-hospital cardiac arrest. Bystander cardio-pulmonary resuscitation was initiated and defibrillation was performed via an automated external defibrillator (AED) shortly after paramedics arrived at the scene, restoring sinus rhythm and spontaneous circulation...
May 11, 2017: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28549535/relationships-of-measured-iohexol-gfr-and-estimated-gfr-with-ckd-related-biomarkers-in-children-and-adolescents
#19
Derek K Ng, George J Schwartz, Bradley A Warady, Susan L Furth, Alvaro Muñoz
BACKGROUND: 2 valid and reliable estimated glomerular filtration rate (GFR) equations for the pediatric population have been developed from directly measured GFR data in the Chronic Kidney Disease in Children (CKiD) cohort: the full CKiD and bedside CKiD equations. Although adult GFR estimating equations replicate relationships of measured GFR with biomarkers, it is unclear whether similar patterns exist among children and adolescents with chronic kidney disease (CKD). STUDY DESIGN: Prospective cohort study in children and adolescents...
May 24, 2017: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/28549429/sleep-characteristics-in-child-and-adolescent-offspring-of-parents-with-bipolar-disorder-a-case-control-study
#20
Antonin Sebela, Tomas Novak, David Kemlink, Michal Goetz
BACKGROUND: Impairment of sleep and circadian rhythm is a typical feature of bipolar disorder (BD). We carried out an exploratory cross-sectional case-control study to extend the knowledge of sleep characteristics in offspring at risk for BD. METHODS: We investigated 42 offspring of bipolar parents (OB) (mean age 12.5 ± 3.2) and 42 sex and age matched comparison offspring of healthy parents. We administered the Pediatric Sleep Questionnaire, the Morningness/Eveningness Questionnaire and The General Behavior Inventory Sleep Subscale (GBISS) to assess circadian preference, and to identify sleep impairment symptoms...
May 26, 2017: BMC Psychiatry
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