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https://www.readbyqxmd.com/read/27891759/sociodemographic-correlates-and-family-aggregation-of-leukocyte-telomere-length-in-adults-and-children-from-mesoamerica
#1
Kerry S Flannagan, Erica C Jansen, Laura S Rozek, Katie M Rentschler, Ana Victoria Roman, Manuel Ramirez-Zea, Eduardo Villamor
OBJECTIVE: Telomere length is a biomarker of cumulative stress and inflammation related to chronic disease risk. We examined the associations of leukocyte telomere length (LTL) with sociodemographic and anthropometric variables and estimated LTL family aggregation in Central America, a region with a high burden of chronic disease where LTL has not been studied. METHODS: We conducted a cross-sectional study of 174 school age children and their parents in the capital cities of Belize, Honduras, Nicaragua, Costa Rica, Panama, and the city of Tuxtla-Gutierrez in Mexico...
November 28, 2016: American Journal of Human Biology: the Official Journal of the Human Biology Council
https://www.readbyqxmd.com/read/27882241/immune-profile-of-honduran-schoolchildren-with-intestinal-parasites-the-skewed-response-against-geohelminths
#2
José Antonio Gabrie, María Mercedes Rueda, Carol Anahelka Rodríguez, Maritza Canales, Ana Lourdes Sanchez
Soil-transmitted helminth infections typically induce a type-2 immune response (Th2), but no immunoepidemiological studies have been undertaken in Honduras, an endemic country where the main control strategy is children's annual deworming. We aimed to characterize the immune profile of Honduran schoolchildren harbouring these parasitoses. Demographic and epidemiological data were obtained through a survey; nutritional status was assessed through anthropometry; intestinal parasites were diagnosed by formol-ether and Kato-Katz; and blood samples were collected to determine immunological markers including Th1/Th2 cytokines, IgE, and eosinophil levels...
2016: Journal of Parasitology Research
https://www.readbyqxmd.com/read/27876005/a-predictive-model-to-differentiate-dengue-from-other-febrile-illness
#3
Eduardo Fernández, Marek Smieja, Stephen D Walter, Mark Loeb
BACKGROUND: Dengue is a major public health problem in tropical and subtropical countries and has a presentation similar to other febrile illnesses. Since laboratory confirmation is frequently delayed, the majority of dengue cases are diagnosed based on symptoms. The objective of this study was to identify clinical, hematological and demographical parameters that could be used as predictors of dengue fever among patients with febrile illness. METHODS: We conducted a retrospective cohort study of 548 patients presenting with febrile syndrome to the largest public hospitals in Honduras...
November 22, 2016: BMC Infectious Diseases
https://www.readbyqxmd.com/read/27783617/genetic-diversity-and-population-structure-of-mesoamerican-jaguars-panthera-onca-implications-for-conservation-and-management
#4
Claudia Wultsch, Anthony Caragiulo, Isabela Dias-Freedman, Howard Quigley, Salisa Rabinowitz, George Amato
Mesoamerican jaguars (Panthera onca) have been extirpated from over 77% of their historic range, inhabiting fragmented landscapes at potentially reduced population sizes. Maintaining and restoring genetic diversity and connectivity across human-altered landscapes has become a major conservation priority; nonetheless large-scale genetic monitoring of natural populations is rare. This is the first regional conservation genetic study of jaguars to primarily use fecal samples collected in the wild across five Mesoamerican countries: Belize, Costa Rica, Guatemala, Honduras, and Mexico...
2016: PloS One
https://www.readbyqxmd.com/read/27777178/proteomic-analysis-of-venom-variability-and-ontogeny-across-the-arboreal-palm-pitvipers-genus-bothriechis
#5
Davinia Pla, Libia Sanz, Mahmood Sasa, Manuel E Acevedo, Quetzal Dwyer, Jordi Durban, Alicia Pérez, Yania Rodriguez, Bruno Lomonte, Juan J Calvete
: Bothriechis is a genus of eleven currently recognized slender and arboreal venomous snakes, commonly called palm-pitvipers that range from southern Mexico to northern South America. Despite dietary studies suggesting that palm-pitvipers are generalists with an ontogenetic shift toward endothermic prey, venom proteomic analyses have revealed remarkable divergence between the venoms of the Costa Rican species, B. lateralis, B. schlegelii, B. supraciliaris, and B. nigroviridis. To achieve a more complete picture of the venomic landscape across Bothriechis, the venom proteomes of biodiversity of the northern Middle American highland palm-pitvipers, B...
October 21, 2016: Journal of Proteomics
https://www.readbyqxmd.com/read/27764959/-love-and-trust-you-can-be-blinded-hiv-risk-within-relationships-among-latina-women-in-miami-florida
#6
Gladys E Ibañez, Elaine Whitt, Tenesha Avent, Steve S Martin, Leah M Varga, Miguel A Cano, Daniel J O'Connell
OBJECTIVES: Latina women are disproportionately affected by HIV in the US, and account for 30% of all HIV infections in Miami-Dade County, Florida. The main risk for Latina women is heterosexual contact. Little is known about the relational and cultural factors that may impact women's HIV risk perception. This study aims to describe Latina women's perception of their HIV risk within a relational, cultural, and linguistic context. DESIGN: Eight focus groups of Latina women (n = 28), four English speaking groups and four Spanish speaking groups, were conducted between December 2013 and May 2014...
October 21, 2016: Ethnicity & Health
https://www.readbyqxmd.com/read/27761504/data-on-medicinal-plants-used-in-central-america-to-manage-diabetes-and-its-sequelae-skin-conditions-cardiovascular-disease-kidney-disease-urinary-problems-and-vision-loss
#7
Peter Giovannini, Melanie-Jayne R Howes, Sarah E Edwards
The data described in this article is related to the review article "Medicinal plants used in the traditional management of diabetes and its sequelae in Central America: a review" (Giovannini et al., 2016) [1]. We searched publications on the useful plants of Central America in databases and journals by using selected relevant keywords. We then extracted reported uses of medicinal plants within the disease categories: diabetes mellitus, kidney disease, urinary problems, skin diseases and infections, cardiovascular disease, sexual dysfunction, vision loss, and nerve damage...
June 2016: Data in Brief
https://www.readbyqxmd.com/read/27754537/contrasting-trends-of-tuberculosis-in-the-cities-of-san-pedro-sula-and-tegucigalpa-honduras-2005-2014
#8
Cecilia Varela-Martínez, Zaida E Yadon, Diana Marín, Einar Heldal
Objective To 1) describe and compare the trends of tuberculosis (TB) case notification rates (CNRs) and treatment outcomes in the two largest cities in Honduras (San Pedro Sula and Tegucigalpa) for the period 2005-2014 and 2) identify possible related socioeconomic and health sector factors. Methods This retrospective ecological operational research study used aggregated data from the National TB Program (socioeconomic and health sector information and individual data from the 2014 TB case notification report)...
January 2016: Revista Panamericana de Salud Pública, Pan American Journal of Public Health
https://www.readbyqxmd.com/read/27748649/prolonged-detection-of-zika-virus-in-vaginal-secretions-and-whole-blood
#9
Kristy O Murray, Rodion Gorchakov, Anna R Carlson, Rebecca Berry, Lilin Lai, Muktha Natrajan, Melissa N Garcia, Armando Correa, Shital M Patel, Kjersti Aagaard, Mark J Mulligan
Infection with Zika virus is an emerging public health crisis. We observed prolonged detection of virus RNA in vaginal mucosal swab specimens and whole blood for a US traveler with acute Zika virus infection who had visited Honduras. These findings advance understanding of Zika virus infection and provide data for additional testing strategies.
January 15, 2017: Emerging Infectious Diseases
https://www.readbyqxmd.com/read/27703240/antibody-titres-and-boosting-after-natural-malaria-infection-in-bk-se36-vaccine-responders-during-a-follow-up-study-in-uganda
#10
Masanori Yagi, Nirianne M Q Palacpac, Kazuya Ito, Yuko Oishi, Sawako Itagaki, Betty Balikagala, Edward H Ntege, Adoke Yeka, Bernard N Kanoi, Osbert Katuro, Hiroki Shirai, Wakaba Fukushima, Yoshio Hirota, Thomas G Egwang, Toshihiro Horii
The malaria vaccine BK-SE36 is a recombinant protein (SE36) based on the Honduras 1 serine repeat antigen-5 of Plasmodium falciparum, adsorbed to aluminium hydroxide gel. The phase Ib trial in Uganda demonstrated the safety and immunogenicity of BK-SE36. Ancillary analysis in the follow-up study of 6-20 year-old volunteers suggest significant differences in time to first episodes of clinical malaria in vaccinees compared to placebo/control group. Here, we aimed to get further insights into the association of anti-SE36 antibody titres and natural P...
October 5, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27672413/results-of-a-phase-2-efficacy-and-safety-study-with-sb204-an-investigational-topical-nitric-oxide-releasing-drug-for-the-treatment-of-acne-vulgaris
#11
Hilary Baldwin, Daisy Blanco, Charles McKeever, Nelly Paz, Ynca Nina Vasquez, John Quiring, Carolyn Enloe, Emily De León, Nathan Stasko
OBJECTIVE: To compare efficacy, tolerability, and safety of two concentrations of topical SB204 and vehicle twice daily for 12 weeks in the treatment of acne vulgaris. DESIGN: Randomized, double-blind, placebo-controlled, three-arm, Phase 2 study. SETTING: Dominican Republic, Panama, and Honduras. PARTICIPANTS: Subjects with acne, age 12 to 40, with 25 to 70 noninflammatory lesions, 20 to 40 inflammatory lesions, and a baseline Investigator's Global Assessment score of mild, moderate, or severe...
August 2016: Journal of Clinical and Aesthetic Dermatology
https://www.readbyqxmd.com/read/27671172/community-informed-health-promotion-to-improve-health-behaviors-in-honduras
#12
Brittney J Sullivan, Janet Prvu Bettger
BACKGROUND: Honduras is the second poorest country in Central America. The already high burden of disease is disproportionately worse among individuals with less education and limited access to health care. Community engagement is needed to bridge the gap in health care resources with the need for health promotion and education. Culturally relevant health promotion activities can foster transcultural partnerships. PURPOSE: The purpose of this study was to partner nursing students with village leaders to assess a community's health needs and implement health promotion activities in Honduras...
September 26, 2016: Journal of Transcultural Nursing: Official Journal of the Transcultural Nursing Society
https://www.readbyqxmd.com/read/27667956/five-new-species-of-trigonopeltastes-burmeister-and-schaum-from-central-america-with-new-country-records-for-other-new-world-trichiini-coleoptera-scarabaeidae-cetoniinae
#13
Andrew B T Smith
Five new species of Trigonopeltastes Burmeister and Schaum, 1840 are described: Trigonopeltastes arborfloricola sp. n. from Nicaragua, Trigonopeltastes formidulosus sp. n. from Costa Rica, Trigonopeltastes henryi sp. n. from Costa Rica, Trigonopeltastes mombachoensis sp. n. from Nicaragua, and Trigonopeltastes warneri sp. n. from Belize and Guatemala. An updated key to species of Trigonopeltastes is presented. Trigonopeltastes nigrinus Bates, 1889 and Trigonopeltastes carus Bates, 1889 are placed in synonymy with Trigonopeltastes geometricus Schaum, 1841, syn...
2016: ZooKeys
https://www.readbyqxmd.com/read/27660898/senseless-violence-against-central-american-unaccompanied-minors-historical-background-and-call-for-help
#14
Cheryl B Sawyer, Judith Márquez
The southwestern U.S. border has recently seen a significant increase in the number of unaccompanied children from Honduras, Guatemala, and El Salvador illegally crossing the Mexican border into the United States. Many of these children leave home to flee violence, starvation, impoverished living conditions, or other life-threatening situations. The treatment of acute stress, anxiety, and depression associated with traumatic events is crucial in helping these children address these negative psychological events they have experienced so that they can move forward with their lives...
September 23, 2016: Journal of Psychology
https://www.readbyqxmd.com/read/27612954/pigs-immunized-with-a-novel-e2-subunit-vaccine-are-protected-from-subgenotype-heterologous-classical-swine-fever-virus-challenge
#15
Rachel Madera, Wenjie Gong, Lihua Wang, Yulia Burakova, Karen Lleellish, Amy Galliher-Beckley, Jerome Nietfeld, Jamie Henningson, Kaimin Jia, Ping Li, Jianfa Bai, John Schlup, Scott McVey, Changchun Tu, Jishu Shi
BACKGROUND: Classical swine fever (CSF) or hog cholera is a highly contagious swine viral disease. CSF endemic countries have to use routine vaccination with modified live virus (MLV) vaccines to prevent and control CSF. However, it is impossible to serologically differentiate MLV vaccinated pigs from those infected with CSF virus (CSFV). The aim of this study is to develop a one-dose E2-subunit vaccine that can provide protection against CSFV challenge. We hypothesize that a vaccine consisting of a suitable adjuvant and recombinant E2 with natural conformation may induce a similar level of protection as the MLV vaccine...
2016: BMC Veterinary Research
https://www.readbyqxmd.com/read/27609776/prevalence-and-sociodemographic-correlates-of-metabolic-syndrome-in-school-aged-children-and-their-parents-in-nine-mesoamerican-countries
#16
Eduardo Villamor, Caitlin C Finan, Manuel Ramirez-Zea, Ana Victoria Roman
OBJECTIVE: To ascertain the prevalence and sociodemographic correlates of cardiometabolic risk factors in adults and school-aged children from Mesoamerica. DESIGN: Cross-sectional study with convenience sampling. In adults, metabolic syndrome was defined according to the National Cholesterol Education Program's Adult Treatment Panel III (ATP III) criteria. In children, we calculated a continuous sex- and age-standardized metabolic risk score using variables corresponding to adult ATP III criteria...
September 9, 2016: Public Health Nutrition
https://www.readbyqxmd.com/read/27601517/sequential-chikungunya-and-zika-virus-infections-in-a-traveler-from-honduras
#17
Francesca F Norman, Sandra Chamorro, Ana Vázquez, María-Paz Sánchez-Seco, José-Antonio Pérez-Molina, Begoña Monge-Maillo, María-Jesús Vivancos, Mario Rodríguez-Dominguez, Juan-Carlos Galán, Fernando de Ory, Rogelio López-Vélez
Zika virus (ZIKV) and chikungunya virus (CHIKV) are currently circulating in overlapping areas in the American continents and may both be transmitted by Aedes spp. mosquitoes. The first documented case, to the authors' knowledge, of sequential CHIKV and ZIKV infections diagnosed in a nonendemic area in a returning traveler is reported. The implications for heightened clinical surveillance for these infections and specific patient recommendations are emphasized.
November 2, 2016: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/27601343/potential-impact-of-dengue-vaccination-insights-from-two-large-scale-phase-iii-trials-with-a-tetravalent-dengue-vaccine
#18
Laurent Coudeville, Nicolas Baurin, Maïna L'Azou, Bruno Guy
BACKGROUND: A tetravalent dengue vaccine demonstrated its protective efficacy in two phase III efficacy studies. Results from these studies were used to derive vaccination impact in the five Asian (Indonesia, Malaysia, Philippines, Thailand, Vietnam) and the five Latin American countries (Brazil, Colombia, Honduras, Mexico and Puerto Rico) participating in these trials. METHODS: Vaccination impact was investigated with an age-structured, host-vector, serotype-specific compartmental model...
December 7, 2016: Vaccine
https://www.readbyqxmd.com/read/27562685/estimating-and-mapping-the-incidence-of-dengue-and-chikungunya-in-honduras-during-2015-using-geographic-information-systems-gis
#19
Lysien I Zambrano, Manuel Sierra, Bredy Lara, Iván Rodríguez-Núñez, Marco T Medina, Carlos O Lozada-Riascos, Alfonso J Rodríguez-Morales
Geographical information systems (GIS) use for development of epidemiological maps in dengue has been extensively used, however not in other emerging arboviral diseases, nor in Central America. Surveillance cases data (2015) were used to estimate annual incidence rates of dengue and chikungunya (cases/100,000 pop) to develop the first maps in the departments and municipalities of Honduras. The GIS software used was Kosmo Desktop 3.0RC1(®). Four thematic maps were developed according departments, municipalities, diseases incidence rates...
August 22, 2016: Journal of Infection and Public Health
https://www.readbyqxmd.com/read/27560962/identifying-ancient-settlement-patterns-through-lidar-in-the-mosquitia-region-of-honduras
#20
Christopher T Fisher, Juan Carlos Fernández-Diaz, Anna S Cohen, Oscar Neil Cruz, Alicia M Gonzáles, Stephen J Leisz, Florencia Pezzutti, Ramesh Shrestha, William Carter
The Mosquitia ecosystem of Honduras occupies the fulcrum between the American continents and as such constitutes a critical region for understanding past patterns of socio-political development and interaction. Heavy vegetation, rugged topography, and remoteness have limited scientific investigation. This paper presents prehistoric patterns of settlement and landuse for a critical valley within the Mosquitia derived from airborne LiDAR scanning and field investigation. We show that (i) though today the valley is a wilderness it was densely inhabited in the past; (ii) that this population was organized into a three-tiered system composed of 19 settlements dominated by a city; and, (iii) that this occupation was embedded within a human engineered landscape...
2016: PloS One
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