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https://www.readbyqxmd.com/read/28651014/a-decade-of-haart-in-latin-america-long-term-outcomes-among-the-first-wave-of-hiv-patients-to-receive-combination-therapy
#1
Marcelo J Wolff, Mark J Giganti, Claudia P Cortes, Pedro Cahn, Beatriz Grinsztejn, Jean W Pape, Denis Padgett, Juan Sierra-Madero, Eduardo Gotuzzo, Stephany N Duda, Catherine C McGowan, Bryan E Shepherd
BACKGROUND: In Latin America, the first wave of HIV-infected patients initiated highly active antiretroviral therapy (HAART) 10 or more years ago. Characterizing their treatment experience and corresponding outcomes across a decade of HAART may yield insights relevant to the ongoing care of such patients and those initiating HAART more recently in similar clinical settings. METHODS: This retrospective study included adults initiating HAART before 2004 at 8 sites in Argentina, Brazil, Chile, Haiti, Honduras, and Mexico...
2017: PloS One
https://www.readbyqxmd.com/read/28648543/seasonal-influenza-vaccine-effectiveness-against-laboratory-confirmed-influenza-hospitalizations-latin-america-2013
#2
Nathalie El Omeiri, Eduardo Azziz-Baumgartner, Mark G Thompson, Wilfrido Clará, Mauricio Cerpa, Rakhee Palekar, Sara Mirza, Alba María Ropero-Álvarez
BACKGROUND: Despite widespread utilization of influenza vaccines, effectiveness (VE) has not been routinely measured in Latin America. METHODS: We used a case test-negative control design to estimate trivalent inactivated influenza VE against laboratory-confirmed influenza among hospitalized children aged 6months-5years and adults aged ≥60years which are age-groups targeted for vaccination. We sought persons with severe acute respiratory infections (SARI), hospitalized at 71 sentinel hospitals in Argentina, Brazil, Chile, Colombia, Costa Rica, El Salvador, Honduras, Panama, and Paraguay during January-December 2013...
June 22, 2017: Vaccine
https://www.readbyqxmd.com/read/28645708/identification-of-major-routes-of-hiv-transmission-throughout-mesoamerica
#3
Antoine Chaillon, Santiago Avila-Ríos, Joel O Wertheim, Ann Dennis, Claudia García-Morales, Daniela Tapia-Trejo, Carlos Mejía-Villatoro, Juan M Pascale, Guillermo Porras-Cortés, Carlos J Quant-Durán, Ivette Lorenzana, Rita I Meza, Elsa Y Palou, Marvin Manzanero, Rolando A Cedillos, Gustavo Reyes-Terán, Sanjay R Mehta
BACKGROUND: Migration and travel are major drivers of the spread of infectious diseases. Geographic proximity and a common language facilitate travel and migration in Mesoamerica, which in turn could affect the spread of HIV in the region. METHODS: 6092 HIV-1 subtype B partial pol sequences sampled from unique antiretroviral treatment-naïve individuals from Mexico (40.7%), Guatemala (24.4%), Honduras (19%), Panama (8.2%), Nicaragua (5.5%), Belize (1.4%), and El Salvador (0...
June 20, 2017: Infection, Genetics and Evolution
https://www.readbyqxmd.com/read/28629204/paternal-risk-factors-for-oral-clefts-in-northern-africans-southeast-asians-and-central-americans
#4
Stephanie Ly, Madeleine L Burg, Ugonna Ihenacho, Frederick Brindopke, Allyn Auslander, Kathleen S Magee, Pedro A Sanchez-Lara, Thi-Hai-Duc Nguyen, Viet Nguyen, Maria Irene Tangco, Angela Rose Hernandez, Melissa Giron, Fouzia J Mahmoudi, Yves A DeClerck, William P Magee Iii, Jane C Figueiredo
While several studies have investigated maternal exposures as risk factors for oral clefts, few have examined paternal factors. We conducted an international multi-centered case-control study to better understand paternal risk exposures for oral clefts (cases = 392 and controls = 234). Participants were recruited from local hospitals and oral cleft repair surgical missions in Vietnam, the Philippines, Honduras, and Morocco. Questionnaires were administered to fathers and mothers separately to elicit risk factor and family history data...
June 19, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28627201/grado-de-malnutrici%C3%A3-n-y-su-relaci%C3%A3-n-con-los-principales-factores-estructurales-y-alimentarios-de-la-poblaci%C3%A3-n-preescolar-hondure%C3%A3-a-prevalencia-de-la-lactancia-materna-en-los-mismos
#5
Lorena Fernández Palacios, Elsa Barrientos Augustinus, Carolina Raudales Urquía, Carmen Frontela Saseta, Gaspar Ros Berruezo
Introducción: la desnutrición infantil sigue siendo un grave problema de salud pública en Honduras, con una prevalencia nacional según valores de referencia de la Organización Mundial de la Salud (OMS) del 29% en niños menores de cinco años. Además, el promedio de desnutrición crónica en la región asciende hasta el 80% en comunidades pobres e indígenas, convirtiendo a Honduras en el segundo país en la región centroamericana con mayor incidencia de desnutrición crónica. Otro de los problemas que presenta la región resulta del abandono precoz de la lactancia materna exclusiva: solo el 29,7% de los menores fue alimentado exclusivamente con leche materna hasta los seis meses...
June 5, 2017: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
https://www.readbyqxmd.com/read/28626298/stress-and-coping-latino-youth-coming-of-age-in-a-new-latino-destination
#6
Maria Brietzke, Krista Perreira
Previous research has linked stress to adverse mental health outcomes among Latino adolescents living in the United States. The mechanism through which this process operates continues to be explored, especially in regions of the country where Latin American immigrants and their children have only recently begun to migrate. Our study aimed to contextualize the processes of stress and coping among Latino adolescents growing up in an emerging Latino destination in the US-North Carolina (NC). All adolescents in our study were either the first or second generation children of immigrants from Latin American countries including Colombia, El Salvador, Honduras, and Mexico...
July 2017: Journal of Adolescent Research
https://www.readbyqxmd.com/read/28575193/the-cost-structure-of-routine-infant-immunization-services-a-systematic-analysis-of-six-countries
#7
Fangli Geng, Christian Suharlim, Logan Brenzel, Stephen C Resch, Nicolas A Menzies
Little information exists on the cost structure of routine infant immunization services in low- and middle-income settings. Using a unique dataset of routine infant immunization costs from six countries, we estimated how costs were distributed across budget categories and programmatic activities, and investigated how the cost structure of immunization sites varied by country and site characteristics. The EPIC study collected data on routine infant immunization costs from 319 sites in Benin, Ghana, Honduras, Moldova, Uganda, Zambia, using a standardized approach...
May 31, 2017: Health Policy and Planning
https://www.readbyqxmd.com/read/28573463/detection-and-identification-of-leishmania-spp-application-of-two-hsp70-based-pcr-rflp-protocols-to-clinical-samples-from-the-new-world
#8
Ana M Montalvo, Jorge Fraga, Dídier Tirado, Gustavo Blandón, Annia Alba, Gert Van der Auwera, Iván Darío Vélez, Carlos Muskus
Leishmaniasis is highly prevalent in New World countries, where several methods are available for detection and identification of Leishmania spp. Two hsp70-based PCR protocols (PCR-N and PCR-F) and their corresponding restriction fragment length polymorphisms (RFLP) were applied for detection and identification of Leishmania spp. in clinical samples recruited in Colombia, Guatemala, and Honduras. A total of 93 cases were studied. The samples were classified into positive or suspected of leishmaniasis according to parasitological criteria...
July 2017: Parasitology Research
https://www.readbyqxmd.com/read/28573007/depth-dependent-effects-of-culling-do-mesophotic-lionfish-populations-undermine-current-management
#9
Dominic A Andradi-Brown, Rachel Grey, Alicia Hendrix, Drew Hitchner, Christina L Hunt, Erika Gress, Konrad Madej, Rachel L Parry, Catriona Régnier-McKellar, Owen P Jones, María Arteaga, Andrea P Izaguirre, Alex D Rogers, Dan A Exton
Invasive lionfish (Pterois volitans and P. miles) have spread widely across the western Atlantic and are recognized as a major threat to native marine biodiversity. Although lionfish inhabit both shallow reefs and mesophotic coral ecosystems (MCEs; reefs from 30 to 150 m depth), the primary management response implemented by many countries has been diver-led culling limited to reefs less than 30 m. However, many reef fish undergo ontogenetic migrations, with the largest and therefore most fecund individuals found at greatest depths...
May 2017: Royal Society Open Science
https://www.readbyqxmd.com/read/28564548/feasibility-of-developing-a-pediatric-telehealth-network-in-honduras-with-international-consultation-support
#10
Mary Brooks, Kenton R Holden, Reyna M Durón, James T McElligott, Andrea Summer
INTRODUCTION: Honduras is the second poorest country in Central America, and roughly 50% of the population lives in rural areas. A telehealth network linking these areas to larger health centers may improve patient access to care, and physician access to educational opportunities. This pilot study assessed the feasibility of establishing a pediatric telehealth network between underserved clinics in Honduras and the Medical University of South Carolina (MUSC). METHODS: Two underserved Honduran clinics were identified and invited to participate in the telehealth network...
April 2017: Rural and Remote Health
https://www.readbyqxmd.com/read/28549381/cervical-cancer-screening-in-rural-mountainous-honduras-knowledge-attitudes-and-barriers
#11
Rachel J Pryor, Nadia Masroor, Michael Stevens, Kakotan Sanogo, Pedro José Hernández O'Hagan, Gonzalo Bearman
INTRODUCTION: Because cervical cancer is the leading cause of cancer mortality in Honduras, this study assessed knowledge, attitudes and barriers to cervical cancer screening services by Papanicolaou smear (pap smear) for women in rural, remote Honduras served by Virginia Commonwealth University's Global Health and Health Disparities Program (GH2DP). METHODS: Two interviewers administered an institutional review board approved, 20 question survey by convenience sample methodology to adult female patients visiting GH2DP clinics in June 2014...
April 2017: Rural and Remote Health
https://www.readbyqxmd.com/read/28548622/fungal-contamination-in-green-coffee-beans-samples-a-public-health-concern
#12
Carla Viegas, Cátia Pacífico, Tiago Faria, Ana Cebola de Oliveira, Liliana Aranha Caetano, Elisabete Carolino, Anita Quintal Gomes, Susana Viegas
Studies on the microbiology of coffee cherries and beans have shown that the predominant toxigenic fungal genera (Aspergillus and Penicillium) are natural coffee contaminants. The aim of this study was to investigate the distribution of fungi in Coffea arabica L. (Arabica coffee) and Coffea canephora L. var. robusta (Robusta coffee) green coffee samples obtained from different sources at the pre-roasting stage. Twenty-eight green coffee samples from different countries of origin (Brazil, Timor, Honduras, Angola, Vietnam, Costa Rica, Colombia, Guatemala, Nicaragua, India, and Uganda) were evaluated...
May 26, 2017: Journal of Toxicology and Environmental Health. Part A
https://www.readbyqxmd.com/read/28543373/acss2-gene-variant-associated-with-cleft-lip-and-palate-in-two-independent-hispanic-populations
#13
Sonam Dodhia, Katrina Celis, Alana Aylward, Yi Cai, Maria E Fontana, Alberto Trespalacios, David C Hoffman, Henry Ostos Alfonso, Sidney B Eisig, Gloria H Su, Wendy K Chung, Joseph Haddad
OBJECTIVES/HYPOTHESIS: A candidate variant (p.Val496Ala) of the ACSS2 gene (T > C missense, rs59088485 variant at chr20: bp37 33509608) was previously found to consistently segregate with nonsyndromic cleft lip and/or palate (NSCLP) in three Honduran families. Objectives of this study were 1) to investigate the frequency of this ACSS2 variant in Honduran unrelated NSCLP patients and unrelated unaffected controls and 2) to investigate the frequency of this variant in Colombian unrelated affected NSCLP patients and unrelated unaffected controls...
May 23, 2017: Laryngoscope
https://www.readbyqxmd.com/read/28538734/zika-virus-evolution-and-spread-in-the-americas
#14
Hayden C Metsky, Christian B Matranga, Shirlee Wohl, Stephen F Schaffner, Catherine A Freije, Sarah M Winnicki, Kendra West, James Qu, Mary Lynn Baniecki, Adrianne Gladden-Young, Aaron E Lin, Christopher H Tomkins-Tinch, Simon H Ye, Daniel J Park, Cynthia Y Luo, Kayla G Barnes, Rickey R Shah, Bridget Chak, Giselle Barbosa-Lima, Edson Delatorre, Yasmine R Vieira, Lauren M Paul, Amanda L Tan, Carolyn M Barcellona, Mario C Porcelli, Chalmers Vasquez, Andrew C Cannons, Marshall R Cone, Kelly N Hogan, Edgar W Kopp, Joshua J Anzinger, Kimberly F Garcia, Leda A Parham, Rosa M Gélvez Ramírez, Maria C Miranda Montoya, Diana P Rojas, Catherine M Brown, Scott Hennigan, Brandon Sabina, Sarah Scotland, Karthik Gangavarapu, Nathan D Grubaugh, Glenn Oliveira, Refugio Robles-Sikisaka, Andrew Rambaut, Lee Gehrke, Sandra Smole, M Elizabeth Halloran, Luis Villar, Salim Mattar, Ivette Lorenzana, Jose Cerbino-Neto, Clarissa Valim, Wim Degrave, Patricia T Bozza, Andreas Gnirke, Kristian G Andersen, Sharon Isern, Scott F Michael, Fernando A Bozza, Thiago M L Souza, Irene Bosch, Nathan L Yozwiak, Bronwyn L MacInnis, Pardis C Sabeti
Although the recent Zika virus (ZIKV) epidemic in the Americas and its link to birth defects have attracted a great deal of attention, much remains unknown about ZIKV disease epidemiology and ZIKV evolution, in part owing to a lack of genomic data. Here we address this gap in knowledge by using multiple sequencing approaches to generate 110 ZIKV genomes from clinical and mosquito samples from 10 countries and territories, greatly expanding the observed viral genetic diversity from this outbreak. We analysed the timing and patterns of introductions into distinct geographic regions; our phylogenetic evidence suggests rapid expansion of the outbreak in Brazil and multiple introductions of outbreak strains into Puerto Rico, Honduras, Colombia, other Caribbean islands, and the continental United States...
June 15, 2017: Nature
https://www.readbyqxmd.com/read/28528713/sociodemographics-and-the-impact-of-a-colostomy-to-indigent-families-and-children-with-colorectal-disorders-in-honduras
#15
W Krois, A J M Dingemans, P X Hernández, M L Metzelder, J Craniotis Rios, C A Reck-Burneo
INTRODUCTION: To describe the social impact of a colostomy on indigent families and affected children with anorectal malformations (ARM) or Hirschsprung's disease (HD) in San Pedro Sula, Honduras, we specifically targeted very low-income households that attended an international medical brigade for ARM and HD in 2016. METHODS: The impact of a colostomy on the families and children's daily life was analyzed by personal interviews with a questionnaire. RESULTS: Twenty families with children were included in the study...
May 12, 2017: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/28514227/real-time-evolution-of-zika-virus-disease-outbreak-roat%C3%A3-n-honduras
#16
Trevor Brooks, Arup Roy-Burman, Cascade Tuholske, Michael P Busch, Sonia Bakkour, Mars Stone, Jeffrey M Linnen, Kui Gao, Jayleen Coleman, Evan M Bloch
A Zika virus disease outbreak occurred in Roatán, Honduras, during September 2015-July 2016. Blood samples and clinical information were obtained from 183 patients given a clinical diagnosis of suspected dengue virus infection. A total of 79 patients were positive for Zika virus, 13 for chikungunya virus, and 6 for dengue virus.
August 17, 2017: Emerging Infectious Diseases
https://www.readbyqxmd.com/read/28511275/direct-detection-of-leishmania-from-clinical-samples
#17
John N Waitumbi, Joshua Bast, Nancy Nyakoe, Charles Magiri, Miguel Quintana, Ratree Takhampunya, Anthony L Schuster, Marshall T Van de Wyngaerde, James C McAvin, Russell E Coleman
The ability to rapidly and accurately diagnose leishmaniasis is a military priority. Testing was conducted to evaluate diagnostic sensitivity and specificity of field-expedient Leishmania genus and visceral Leishmania specific dual-fluorogenic, hydrolysis probe (TaqMan), polymerase chain reaction assays previously established for use in vector surveillance. Blood samples of patients with confirmed visceral leishmaniasis and controls without the disease from Baringo District, Kenya, were tested. Leishmania genus assay sensitivity was 100% (14/14) and specificity was 84% (16/19)...
January 2017: U.S. Army Medical Department Journal
https://www.readbyqxmd.com/read/28459170/clinical-features-and-neurologic-complications-of-children-hospitalized-with-chikungunya-virus-in-honduras
#18
José A Samra, Nancy L Hagood, Andrea Summer, Marco T Medina, Kenton R Holden
The first case of Chikungunya virus in Honduras was identified in 2014. The virus has spread widely across Honduras via the Aedes aegypti mosquito, leading to an outbreak of Chikungunya virus (CHIKV) in 2015 that significantly impacted children. A retrospective chart review of 235 children diagnosed with CHIKV and admitted to the National Autonomous University of Honduras Hospital Escuela (Hospital Escuela) in Tegucigalpa, Honduras, was accomplished with patients who were assessed for clinical features and neurologic complications...
July 2017: Journal of Child Neurology
https://www.readbyqxmd.com/read/28452578/functional-and-quality-of-life-outcomes-of-a-hand-surgery-mission-to-honduras
#19
Carolyn Chuang, Jacob Azurdia, David Asuzu, Kyle T Ragins, Kevin Tomany, Sohel Islam, Steven Williams, John Safanda, J Grant Thomson
BACKGROUND: The objective of this study was to assess functional, quality of life, and satisfaction outcomes of a hand surgery short-term surgical mission (STSM) to Honduras, and determine whether patient demographics and surgery characteristics during a surgical mission correlate with outcome. METHODS: A total of 63 patients who received upper extremity surgery at a week-long hand surgery STSM to Honduras in March 2013 participated in the study. A before-after study design was used...
April 1, 2017: Hand: Official Journal of the American Association for Hand Surgery
https://www.readbyqxmd.com/read/28441094/background-rates-of-disease-in-latin-american-children-from-a-rotavirus-vaccine-study
#20
Marc Baay, Kaatje Bollaerts, Claudio Struchiner, Thomas Verstraeten
BACKGROUND: Knowledge of background rates of adverse events is crucial to assess vaccine safety concerns. We used data from a rotavirus vaccine study (Ruiz-Palacios et al., NEJM, 2006) including 63,225 infants from 11 Latin American countries to investigate reporting rates of serious adverse events (SAEs) among these infants, and describe rates by country, gender, age, and season. METHODS: For this randomized, double-blind, placebo-controlled, phase 3 trial, investigators from Argentina, Brazil, Chile, Colombia, Dominican Republic, Honduras, Mexico, Nicaragua, Panama, Peru, and Venezuela recruited 6-to-13-week-old healthy infants...
April 25, 2017: Human Vaccines & Immunotherapeutics
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