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https://www.readbyqxmd.com/read/29129611/effect-of-sleep-curtailment-on-dietary-behavior-and-physical-activity-a-randomized-crossover-trial
#1
Eri Tajiri, Eiichi Yoshimura, Yoichi Hatamoto, Hiroaki Tanaka, Seiya Shimoda
Our objective was to clarify the effect of sleep curtailment on energy intake (EI) and physical activity under free-living conditions. Participants were 16 healthy women aged 21-22years. A randomized crossover trial design was used to compare a short sleep condition (SS): 4h/night (2:00-6:00) and a control sleep condition (CS): 7h/night (23:00-6:00). Each condition comprised 3 consecutive nights. Sleep duration was assessed using a wristwatch-type accelerometer at home. All living activities except sleeping were free-living...
November 9, 2017: Physiology & Behavior
https://www.readbyqxmd.com/read/29091128/self-care-competence-in-the-administration-of-insulin-in-older-people-aged-70-or-over1
#2
Mayara Sousa Vianna, Patrícia Aparecida Barbosa Silva, Cíntia Vieira do Nascimento, Sônia Maria Soares
OBJECTIVE: to analyze the self-care competence in the administration of insulin performed by older people aged 70 or over. METHOD: cross-sectional study carried out with 148 older people aged 70 or over, who performed self-administration of insulin. Data collection was carried out using a structured questionnaire and an adapted guide for the application of the Scale to Identify Self-Care Competence of Patients with Diabetes, at the participants' home. Data analysis included descriptive and inferential statistical tests, with forward logistic regression...
October 30, 2017: Revista Latino-americana de Enfermagem
https://www.readbyqxmd.com/read/29075301/insulinoma-masquerading-as-a-loss-of-consciousness-in-a-teenage-girl-case-report-and-literature-review
#3
Meghana Gudala, Mahmuda Ahmed, Rushika Conroy, Ksenia Tonyushkina
BACKGROUND: Hypoglycemia due to a pancreatic beta cell neoplasm - insulinoma, is uncommon with only a few cases described. We report on a previously healthy 15-year-old Hispanic female with insulinoma who presented with a loss of consciousness due to hypoglycemia unawareness. CASE PRESENTATION: EM was first brought to the emergency department (ED) after she was found unresponsive at home with point of care (POC) glucose of 29 mg/dL(1.6 mmol/L) documented by emergency medical services (EMS) upon arrival...
2017: International Journal of Pediatric Endocrinology
https://www.readbyqxmd.com/read/28989569/clinical-profile-of-diabetes-at-diagnosis-among-children-and-adolescents-at-an-endocrine-clinic-in-ghana
#4
Emmanuel Ameyaw, Serwah B Asafo-Agyei, Sumithira Thavapalan, Angela C Middlehurst, Graham D Ogle
AIM: To determine the clinical features of diabetes in children and adolescents in Ghana. METHODS: Retrospective review of clinical features of all children and adolescents with new-onset diabetes seen at the paediatric endocrinology clinic of Komfo Anokye Teaching Hospital in Kumasi, from February 2012 to Auguest 2016. RESULTS: One hundred and six subjects presented with diabetes. Ninety (84.9%) were diagnosed by clinical features and family history as type 1, and 16 (15...
September 15, 2017: World Journal of Diabetes
https://www.readbyqxmd.com/read/28966058/-congenital-hyperinsulinism-revealed-by-sudden-infant-death
#5
Anne Guyot, Fanny Moreau, Maxime Eberhard, Jean-Michel Gaulier, François Paraf
We report the case of a girl of 5 and a half months admitted for discomfort and consciousness loss at home and supported on sudden infant death protocol. Workup was negative. Autopsy showed only signs of asphyxia. Microscopic examination of the pancreas showed hypertrophic beta cells of Langerhans islets, explaining death linked to severe hypoglycemia by inappropriate insulin hypersecretion. This observation highlights the importance of the management of sudden infant unexpected death according to the protocol of the National Health Authority, which includes an autopsy with complete sampling, which in this case resulted in a diagnosis of unknown disease the lifetime of the child...
October 2017: Annales de Pathologie
https://www.readbyqxmd.com/read/28949318/psychogeriatric-diagnoses-in-old-people-s-homes-and-negative-health-behavior
#6
Spomenka Tomek-Roksandić, Ivana Popek, Nada Tomasović Mrčela, Zvonimir Šostar, Branko Kolarić, Nina Smolej Narančić, Ana Stavljenić Rukavina, Mate Ljubičić
BACKGROUND: The study was designed as a gerontologic-public health analysis of the relationship between the leading and accompanying psychogeriatric diagnoses and negative health behaviors recorded in the old people's home users, with the aim to evaluate and redefine gerontologic-public health priorities and geroprophylactic measures, with special reference to persons suffering from Alzheimer's disease and other dementias. SUBJECT AND METHODS: Gerontologic-public health indicators obtained by monitoring health care needs of the elderly in specific institutional primary health care at 10 old people's homes (N=1185) in Croatia in 2013 were analyzed using the professional methodology developed at Department of Health Gerontology, Andrija Štampar Teaching Institute of Public Health (Registry List 1 that refers to monitoring specific primary health care needs of elderly at old people's homes)...
September 2017: Psychiatria Danubina
https://www.readbyqxmd.com/read/28942668/recent-exposure-to-hypoglycemia-increases-glucose-variability-following-a-hyper-hypoglycemic-metabolic-challenge-in-t1d
#7
Chiara Fabris, Leon S Farhy, Stacey M Anderson, Ralf M Nass, Boris P Kovatchev, Marc D Breton
AIMS: In type 1 diabetes (T1D), repeated hypoglycemic episodes may reduce hormonal defenses and increase the risk for severe hypoglycemia. In this work, we investigate the effect of a structured hyper/hypoglycemic metabolic challenge on the postintervention glucose variability in T1D subjects studied at home. METHODS: Thirty T1D subjects using insulin pump were monitored with blood glucose meters (SMBG) during a 1-month observation period. After 2 weeks of monitoring, participants were admitted at the University of Virginia Clinical Research Unit to undergo an 8-hour metabolic challenge...
September 1, 2017: Journal of Diabetes Science and Technology
https://www.readbyqxmd.com/read/28938142/insulin-regimens-and-glycemic-control-in-different-parts-of-europe-over-4years-after-starting-insulin-in-people-with-type-2-diabetes-data-from-the-credit-non-interventional-study
#8
Lawrence Blonde, Michel Marre, Maya Vincent, Sandrine Brette, Valerie Pilorget, Nicholas Danchin, Giacomo Vespasiani, Philip Home
AIMS: A number of insulin regimens are used in type 2 diabetes. This analysis aims to better understand the evolution of insulin therapy in different regions of Europe. METHODS: Data from people starting any insulin were collected in eastern Europe (EEur: Croatia, Russia, Ukraine), northern Europe (NEur: Finland, Germany, UK) and southern Europe (SEur: France, Italy, Portugal, Spain). Retrospective data on starting insulin and prospective follow-up data were extracted from clinical records...
August 31, 2017: Diabetes Research and Clinical Practice
https://www.readbyqxmd.com/read/28912356/biomarkers-of-disease-can-be-detected-in-mice-as-early-as-4-weeks-after-initiation-of-exposure-to-third-hand-smoke-levels-equivalent-to-those-found-in-homes-of-smokers
#9
Neema Adhami, Yuxin Chen, Manuela Martins-Green
Third-hand smoke (THS) is a newly discovered environmental health hazard that results from accumulation and aging of second-hand smoke (SHS) toxins on surfaces where smoking has occurred. Our objective was to determine whether there is a time-dependent effect of THS exposure on health. Using an in vivo exposure mouse system that mimics exposure of humans to THS, we investigated its effects on biomarkers found in serum, and in liver and brain tissues. Mice were exposed to THS for 1, 2, 4, or 6 months and brain, liver, and serum were collected...
October 1, 2017: Clinical Science (1979-)
https://www.readbyqxmd.com/read/28911254/acceptance-of-home-blood-glucose-monitoring-by-owners-of-recently-diagnosed-diabetic-cats-and-impact-on-quality-of-life-changes-in-cat-and-owner
#10
Katarina Hazuchova, Ruth Gostelow, Christopher Scudder, Yaiza Forcada, David B Church, Stijn Jm Niessen
Objectives This study aimed to evaluate the acceptance of home blood glucose monitoring (HBGM) by owners of recently diagnosed diabetic cats, and the impact of choosing HBGM on the quality of life (QoL) changes of cat and owner, in addition to glycaemic changes during 6 months of follow-up. Methods Owners of cats diagnosed with diabetes mellitus (DM) and treated with insulin for 6-20 weeks were divided into an HBGM group and a non-HBGM group, based on their ability and willingness to perform HBGM after a standardised instruction session...
September 1, 2017: Journal of Feline Medicine and Surgery
https://www.readbyqxmd.com/read/28905317/healthcare-resource-utilization-and-costs-associated-with-ketosis-events-in-pediatric-and-adult-patients-with-type-1-diabetes-mellitus-in-the-uk
#11
Nandu Thalange, Natalie Valerie Jane Aldhouse, Helen Kitchen, Daniel Howard, Deniz Tutkunkardas, Jonas Håkan-Bloch
INTRODUCTION: Ketosis is a metabolic state associated with insulin deficiency. Untreated, it develops into diabetic ketoacidosis, a significant contributor to mortality and morbidity in people with type 1 diabetes mellitus (T1DM). Little is understood about how patients utilize healthcare resources during ketosis events. This study aimed to identify and quantify healthcare resource utilization and provide estimates of associated costs of ketosis events in T1DM, treated unaided or with healthcare professional (HCP) assistance in the UK...
October 2017: Diabetes Therapy: Research, Treatment and Education of Diabetes and related Disorders
https://www.readbyqxmd.com/read/28898714/effect-of-follow-up-by-a-hospital-diabetes-care-team-on-diabetes-control-at-one-year-after-discharge-from-the-hospital
#12
Rajesh Garg, Shelley Hurwitz, Raquel Rein, Brooke Schuman, Patricia Underwood, Shreya Bhandari
AIM: This study was conducted to evaluate the effect of continued follow-up by a hospital diabetes team on HbA1c at 1-year after discharge. METHODS: Adults with HbA1c ≥8% (64mmol/mol), undergoing an elective surgery, were treated in the perioperative period and randomized to continued care (CC) or the usual care (UC) after discharge. Patients in the CC group received weekly to monthly phone calls from a diabetes specialist nurse practitioner (NP) to review their home blood glucose values, diet, exercise, and medications...
August 24, 2017: Diabetes Research and Clinical Practice
https://www.readbyqxmd.com/read/28890218/serum-perfluoroalkyl-substances-and-cardiometabolic-consequences-in-adolescents-exposed-to-the-world-trade-center-disaster-and-a-matched-comparison-group
#13
Tony T Koshy, Teresa M Attina, Akhgar Ghassabian, Joseph Gilbert, Lauren K Burdine, Michael Marmor, Masato Honda, Dinh Binh Chu, Xiaoxia Han, Yongzhao Shao, Kurunthachalam Kannan, Elaine M Urbina, Leonardo Trasande
BACKGROUND: Large amounts of various chemical contaminants, including perfluoroalkyl substances (PFASs), were released at the time of the World Trade Center (WTC) disaster. Thousands of children who lived and/or attended school near the disaster site were exposed to these substances but few studies have examined the possible consequences related to these exposures. OBJECTIVES: To examine the relationship of PFASs serum levels with cardiometabolic profile in children and adolescents enrolled in the World Trade Center Health Registry (WTCHR) and a matched comparison group...
December 2017: Environment International
https://www.readbyqxmd.com/read/28803675/the-yale-fitness-intervention-trial-in-female-cancer-survivors-cardiovascular-and-physiological-outcomes
#14
MULTICENTER STUDY
M Tish Knobf, Sangchoon Jeon, Barbara Smith, Lyndsay Harris, Siobhan Thompson, Mitchel R Stacy, Karl Insogna, Albert J Sinusas
BACKGROUND: Induced premature menopause and cardio-toxic therapy increase cardiovascular disease risk in female cancer survivors. OBJECTIVE: To compare the effects of a 12 month aerobic-resistance fitness center intervention to home based physical activity on cardiovascular function and metabolic risk factors. METHODS: Subjects (N = 154) who had completed primary and/or adjuvant chemotherapy (past 3 years) were randomized to a fitness center intervention or a home based group...
September 2017: Heart & Lung: the Journal of Critical Care
https://www.readbyqxmd.com/read/28792863/addition-of-insulin-to-parenteral-nutrition-for-control-of-hyperglycemia
#15
Adam McCulloch, Vishakha Bansiya, Jeremy M Woodward
Administration of parenteral nutrition (PN) may result in hyperglycemia in patients with preexisting diabetes or disease-related insulin resistance, and it can be associated with increased rates of complications. Treatment requires insulin therapy. Insulin can be administered subcutaneously, intravenously via a variable rate sliding scale, or by adding it directly to the PN. The last method is a potentially attractive technique for a number of reasons-it could deliver the insulin intravenously at a steady rate alongside carbohydrates, and in malnourished patients with little subcutaneous tissue, it may prevent the need for frequent insulin injections...
August 1, 2017: JPEN. Journal of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/28790874/lack-of-change-in-glucose-metabolism-in-eszopiclone-treated-primary-insomnia-patients
#16
Orfeu M Buxton, Milena K Pavlova, Shawn P O'Connor, Wei Wang, John W Winkelman
STUDY OBJECTIVES: Primary insomnia (PI) may increase diabetes risk. We tested the hypothesis that the effects of PI on glucose metabolism could be improved by 2 months of pharmacological treatment. METHODS: Adult men and women meeting clinical criteria for PI were studied (n=20, body mass index 25.1±2.7 kg/m(2), age 39.7±7.9) in a randomized, double-blind, placebo-controlled clinical trial. The study consisted of two 1-day inpatient admissions to a General Clinical Research Center separated by 2 months of at-home treatment with 3 mg eszopiclone or placebo...
2017: Nature and Science of Sleep
https://www.readbyqxmd.com/read/28753161/impact-of-exercise-on-cardiometabolic-component-risks-in-spinal-cord-injured-humans
#17
Tom E Nightingale, Jean-Philippe Walhin, Dylan Thompson, James L J Bilzon
PURPOSE: Spinal cord injury (SCI) creates a complex pathology, characterized by low levels of habitual physical activity and an increased risk of cardiometabolic disease. This study aimed to assess the effect of a moderate-intensity upper-body exercise training intervention on biomarkers of cardiometabolic component risks, adipose tissue metabolism, and cardiorespiratory fitness in persons with SCI. METHODS: Twenty-one inactive men and women with chronic (>1 yr) SCI (all paraplegic injuries) 47 ± 8 yr of age (mean ± SD) were randomly allocated to either a 6-wk prescribed home-based exercise intervention (INT; n = 13) or control group (CON; n = 8)...
December 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/28751962/autologous-bone-marrow-derived-stem-cell-therapy-in-patients-with-type-2-diabetes-mellitus-defining-adequate-administration-methods
#18
Vikas Sood, Anil Bhansali, Bhagwant Rai Mittal, Baljinder Singh, Neelam Marwaha, Ashish Jain, Niranjan Khandelwal
AIM: To carry out randomized trial for evaluating effects of autologous bone marrow derived stem cell therapy (ABMSCT) through different routes. METHODS: Bone marrow aspirate was taken from the iliac crest of patients. Bone marrow mononuclear cells were separated and purified using centrifugation. These cells were then infused in a total of 21 patients comprising three groups of 7 patients each. Cells were infused into the superior pancreaticoduodenal artery (Group I), splenic artery (Group II) and through the peripheral intravenous route (Group III)...
July 15, 2017: World Journal of Diabetes
https://www.readbyqxmd.com/read/28737991/lowering-cost-share-may-improve-rates-of-home-glucose-monitoring-among-patients-with-diabetes-using-insulin
#19
Yiqiong Xie, Abiy Agiro, Kevin Bowman, Andrea DeVries
BACKGROUND: Not much is known about the extent to which lower cost share for blood glucose strips is associated with persistent filling. OBJECTIVE: To evaluate the relationship between cost sharing for blood glucose testing strips and continued use of testing strips. METHODS: This is a retrospective observational study using medical and pharmacy claims data integrated with laboratory hemoglobin A1c (A1c) values for patients using insulin and blood glucose testing strips...
August 2017: Journal of Managed Care & Specialty Pharmacy
https://www.readbyqxmd.com/read/28720103/an-information-and-communication-technology-based-centralized-clinical-trial-to-determine-the-efficacy-and-safety-of-insulin-dose-adjustment-education-based-on-a-smartphone-personal-health-record-application-a-randomized-controlled-trial
#20
Gyuri Kim, Ji Cheol Bae, Byoung Kee Yi, Kyu Yeon Hur, Dong Kyung Chang, Moon-Kyu Lee, Jae Hyeon Kim, Sang-Man Jin
BACKGROUND: A Personal Health Record (PHR) is an online application that allows patients to access, manage, and share their health data. PHRs not only enhance shared decision making with healthcare providers, but also enable remote monitoring and at-home-collection of detailed data. The benefits of PHRs can be maximized in insulin dose adjustment for patients starting or intensifying insulin regimens, as frequent self-monitoring of glucose, self-adjustment of insulin dose, and precise at-home data collection during the visit-to-visit period are important for glycemic control...
July 18, 2017: BMC Medical Informatics and Decision Making
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