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https://www.readbyqxmd.com/read/29110539/nutritional-and-bioactive-compounds-of-commercialized-algae-powders-used-as-food-supplements
#1
Ginés B Martínez-Hernández, Noelia Castillejo, María Del M Carrión-Monteagudo, Francisco Artés, Francisco Artés-Hernández
The main nutritional/bioactive compounds (protein; aminoacids, AA; fucose; minerals; vitamins B12 and C; and total phenolic content, TPC) of nine commercial algae powders, used as food supplements, were studied. Undaria pinnatifida showed the highest protein/aminoacid contents (51.6/54.4 g 100 g(-1)). Among brown macroalgae, Himanthalia elongata showed the highest fucose content (26.3 g kg(-1)) followed by Laminaria ochroleuca (22.5 g kg(-1)). Mineral contents of 15-24% were observed in the algae, being particularly excellent sources of iodine (69...
January 1, 2017: Food Science and Technology International, Ciencia y Tecnología de Los Alimentos Internacional
https://www.readbyqxmd.com/read/28753930/pregnancy-proteinuria-plant-based-supplemented-diets-and-focal-segmental-glomerulosclerosis-a-report-on-three-cases-and-critical-appraisal-of-the-literature
#2
Rossella Attini, Filomena Leone, Benedetta Montersino, Federica Fassio, Fosca Minelli, Loredana Colla, Maura Rossetti, Cristiana Rollino, Maria Grazia Alemanno, Antonella Barreca, Tullia Todros, Giorgina Barbara Piccoli
Chronic kidney disease (CKD) is increasingly recognized in pregnant patients. Three characteristics are associated with a risk of preterm delivery or small for gestational age babies; kidney function reduction, hypertension, and proteinuria. In pregnancy, the anti-proteinuric agents (ACE-angiotensin converting enzyme-inhibitors or ARBS -angiotensin receptor blockers) have to be discontinued for their potential teratogenicity, and there is no validated approach to control proteinuria. Furthermore, proteinuria usually increases as an effect of therapeutic changes and pregnancy-induced hyperfiltration...
July 19, 2017: Nutrients
https://www.readbyqxmd.com/read/28702021/combination-of-metabolomic-and-proteomic-analysis-revealed-different-features-among-lactobacillus-delbrueckii-subspecies-bulgaricus-and-lactis-strains-while-in-vivo-testing-in-the-model-organism-caenorhabditis-elegans-highlighted-probiotic-properties
#3
Elena Zanni, Emily Schifano, Sara Motta, Fabio Sciubba, Claudio Palleschi, Pierluigi Mauri, Giuditta Perozzi, Daniela Uccelletti, Chiara Devirgiliis, Alfredo Miccheli
Lactobacillus delbrueckii represents a technologically relevant member of lactic acid bacteria, since the two subspecies bulgaricus and lactis are widely associated with fermented dairy products. In the present work, we report the characterization of two commercial strains belonging to L. delbrueckii subspecies bulgaricus, lactis and a novel strain previously isolated from a traditional fermented fresh cheese. A phenomic approach was performed by combining metabolomic and proteomic analysis of the three strains, which were subsequently supplemented as food source to the model organism Caenorhabditis elegans, with the final aim to evaluate their possible probiotic effects...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28522351/effect-of-early-supplemental-parenteral-nutrition-in-the-paediatric-icu-a-preplanned-observational-study-of-post-randomisation-treatments-in-the-pepanic-trial
#4
Ilse Vanhorebeek, Sascha Verbruggen, Michaël P Casaer, Jan Gunst, Pieter J Wouters, Jan Hanot, Gonzalo Garcia Guerra, Dirk Vlasselaers, Koen Joosten, Greet Van den Berghe
BACKGROUND: Large randomised controlled trials have shown that early supplemental parenteral nutrition in patients admitted to adult and paediatric intensive care units (PICUs) is harmful. Overdosing of energy with too little protein was suggested as a potential reason for this. This study analysed which macronutrient was associated with harm caused by early supplemental parenteral nutrition in the Paediatric Early versus Late Parenteral Nutrition In Critical Illness (PEPaNIC) randomised trial...
June 2017: Lancet Respiratory Medicine
https://www.readbyqxmd.com/read/27927186/diet-as-a-system-an-observational-study-investigating-a-multi-choice-system-of-moderately-restricted-low-protein-diets
#5
Giorgina Barbara Piccoli, Marta Nazha, Irene Capizzi, Federica Neve Vigotti, Stefania Scognamiglio, Valentina Consiglio, Elena Mongilardi, Marilisa Bilocati, Paolo Avagnina, Elisabetta Versino
BACKGROUND: There is no single, gold-standard, low-protein diet (LPD) for CKD patients; the best compliance is probably obtained by personalization. This study tests the hypothesis that a multiple choice diet network allows patients to attain a good compliance level, and that, in an open-choice system, overall results are not dependent upon the specific diet, but upon the clinical characteristics of the patients. METHODS: Observational study: Three LPD options were offered to all patients with severe or rapidly progressive CKD: vegan diets supplemented with alpha-ketoacids and essential aminoacids; protein-free food in substitution of normal bread and pasta; other (traditional, vegan non supplemented and tailored)...
December 7, 2016: BMC Nephrology
https://www.readbyqxmd.com/read/27854256/natural-deep-eutectic-solvents-nades-as-a-tool-for-bioavailability-improvement-pharmacokinetics-of-rutin-dissolved-in-proline-glycine-after-oral-administration-in-rats-possible-application-in-nutraceuticals
#6
Marta Faggian, Stefania Sut, Beatrice Perissutti, Valeria Baldan, Iztok Grabnar, Stefano Dall'Acqua
There is a need for innovation in plant-derived pharmaceuticals, food supplements and nutraceutical products regarding the use of more eco-sustainable solvents for their extraction. Furthermore, the poor oral bioavailability of several phytochemicals with health promoting effects stimulates the research in the field of pharmaceutical formulations. Natural Deep Eutectic Solvents (NADES) are formed by natural compounds, and can be considered as future solvents being especially useful for the preparation of nutraceuticals and food-grade extracts...
November 14, 2016: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/27388899/adherence-to-ketoacids-essential-amino-acids-supplemented-low-protein-diets-and-new-indications-for-patients-with-chronic-kidney-disease
#7
REVIEW
Denis Fouque, Jing Chen, Wei Chen, Liliana Garneata, S J Hwang, Kamyar Kalantar-Zadeh, Joel D Kopple, William E Mitch, Giorgina Piccoli, Vladimir Teplan, Philippe Chauveau
BACKGROUND: Low protein diets (LPD) have long been prescribed to chronic kidney disease patients with the goals of improving metabolic abnormalities and postpone the start of maintenance dialysis. METHODS: We reviewed the recent literature addressing low protein diets supplemented with ketoacids/essential aminoacids prescribed during chronic kidney disease and their effects on metabolic, nutritional and renal parameters since 2013. RESULTS: We show new information on how to improve adherence to these diets, on metabolic improvement and delay of the dialysis needs, and preliminary data in chronic kidney disease associated pregnancy...
July 7, 2016: BMC Nephrology
https://www.readbyqxmd.com/read/27383313/very-low-calorie-ketogenic-diet-with-aminoacid-supplement-versus-very-low-restricted-calorie-diet-for-preserving-muscle-mass-during-weight-loss-a-pilot-double-blind-study
#8
RANDOMIZED CONTROLLED TRIAL
G Merra, R Miranda, S Barrucco, P Gualtieri, M Mazza, E Moriconi, M Marchetti, T F M Chang, A De Lorenzo, L Di Renzo
OBJECTIVE: Obesity plays a relevant pathophysiological role in the development of health problems, arising as result of complex interaction of genetic, nutritional and metabolic factors. We conducted a dietary intervention case-control randomized trial, to compare the effectiveness on body composition of two nutritional protocols: a very-low-carbohydrate ketogenic diet (VLCKD), integrated by an aminoacid supplement with whey protein, and very low restricted-calorie diet (VLCD). PATIENTS AND METHODS: The clinical study was conducted with a randomized case-control in which twenty-five healthy subjects gave informed consent to participate in the interventional study and were evaluated for their health and nutritional status, by anthropometric, and body composition evaluation...
July 2016: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/26989644/insulin-driven-translational-capacity-is-impaired-in-primary-fibroblasts-of-prader-willi
#9
Cristiana Meneghello, Daniela Segat, Elisabetta Fortunati
Prader-Willi (PW) syndrome is a rare genetic disorder characterized by hypothalamic-pituitary abnormalities and severe hypotonia, hyperphagia, behavioural and psychiatric problems. Absence of satiety leads to severe obesity and frequently to diabetes. Furthermore, adult patients suffer from a severe loss of muscle mass, which severely impacts their quality of life. The mechanisms underlying alterations in muscle growth in PW remain to be clarified. In this study we explored the hypothesis that, in PW cells, alterations of protein synthesis are determined by dysfunctions in the promotion of cell growth...
February 2016: Intractable & Rare Diseases Research
https://www.readbyqxmd.com/read/26986929/toxicity-of-canavanine-in-tomato-solanum-lycopersicum-l-roots-is-due-to-alterations-in-rns-ros-and-auxin-levels
#10
Urszula Krasuska, Olga Andrzejczak, Paweł Staszek, Wojciech Borucki, Agnieszka Gniazdowska
Canavanine (CAN) is non-proteinogenic aminoacid and a structural analog of arginine (Arg). Naturally, CAN occurs in legumes e.g. jack bean and is considered as a strong allelochemical. As a selective inhibitor of inducible nitric oxide synthase in mammalians, it could act as a modifier of nitric oxide (NO) concentration in plants. Modifications in the content of endogenous reactive nitrogen species (RNS) and reactive oxygen species (ROS) influence root structure and architecture, being also under hormonal control...
June 2016: Plant Physiology and Biochemistry: PPB
https://www.readbyqxmd.com/read/25875125/the-pharmacological-and-non-pharmacological-treatment-of-attention-deficit-hyperactivity-disorder-in-children-and-adolescents-protocol-for-a-systematic-review-and-network-meta-analysis-of-randomized-controlled-trials
#11
REVIEW
Ferrán Catalá-López, Brian Hutton, Amparo Núñez-Beltrán, Alain D Mayhew, Matthew J Page, Manuel Ridao, Aurelio Tobías, Miguel A Catalá, Rafael Tabarés-Seisdedos, David Moher
BACKGROUND: Attention deficit hyperactivity disorder (ADHD) is one of the most common neurodevelopmental disorders of children and adolescents, with a significant impact on health services and the community in terms of economic and social burdens. The objective of this systematic review will be to evaluate the comparative efficacy and safety of pharmacological and non-pharmacological treatments in children and adolescents with ADHD. METHODS: Searches involving PubMed/MEDLINE and the Cochrane Database of Systematic Reviews will be used to identify related systematic reviews and relevant randomized trials...
February 27, 2015: Systematic Reviews
https://www.readbyqxmd.com/read/25519493/selenium-an-element-for-life
#12
REVIEW
Leonidas H Duntas, Salvatore Benvenga
This review aims to illustrate the importance of selenium (Se) for maintenance of overall health, especially for the thyroid, immunity, and homeostasis. Furthermore, it outlines the role of Se in reproduction and in virology and discusses the effects of Se supplementation in critical illness. The multifaceted aspects of this essential nutrient have attracted worldwide clinical and research interest in the last few decades. Se exerts its activity in the form of the aminoacid selenocysteine incorporated in selenoproteins...
April 2015: Endocrine
https://www.readbyqxmd.com/read/25246343/the-effectiveness-of-oral-essential-aminoacids-and-aminoacids-containing-dialysate-in-peritoneal-dialysis
#13
Selman Unverdi, Mevlut Ceri, Ebru Uz, Bulent Akgul, Mustafa Altay, Yasemin Kirac, Ali Akcay, Murat Duranay
BACKGROUND/AIM: Oral essential amino acids (AAs) containing supplements (EAS) and AA containing dialysate (ACD) are frequently used in peritoneal dialysis (PD) patients with malnutrition. The present study was conducted to investigate two strategies and compare their effects on the malnutrition status of PD patients. MATERIALS AND METHODS: A total of 31 EAS, 14 ACD patients were enrolled in this study. Serum albumin levels were lower than 3.5 g/dL in all subjects...
October 2014: Renal Failure
https://www.readbyqxmd.com/read/25113619/protein-modification-as-oxidative-stress-marker-in-follicular-fluid-from-women-with-polycystic-ovary-syndrome-the-effect-of-inositol-and-metformin
#14
P Piomboni, R Focarelli, A Capaldo, A Stendardi, V Cappelli, A Cianci, A La Marca, A Luddi, V De Leo
PURPOSE: The purpose of this study was to evaluate the oxidative stress status (OS) of follicular fluid (FF) and the oocyte quality in women with polycystic ovary syndrome (PCOS) undergoing different ovarian stimulation protocols. METHODS: FF samples were collected after gonadotropin administration in association or not with metformin or D-chiro-inositol (DCI). OS status was then evaluated by checking the follicular fluid protein oxidation profile after specific labeling of aminoacidic free-SH groups, and two-dimensional electrophoresis followed by qualitative and semiquantitative analysis...
October 2014: Journal of Assisted Reproduction and Genetics
https://www.readbyqxmd.com/read/24844176/nutritional-treatment-for-acute-and-chronic-traumatic-brain-injury-patients
#15
REVIEW
L Curtis, P Epstein
Proper nutrition is critical for recovery from traumatic brain injury (TBI). Prompt enteral feeding of moderate to severe TBI patients has been associated with significantly lower mortality and rates of infection. Probiotic supplementation has been associated with significantly lower rates of infection in TBI and other trauma patients. Human studies have suggested that supplementation with omega 3 fats, vitamin D, N-Acetylcysteine, branched chain amino acids, and zinc may be helpful for recovery from TBI. Animal TBI models have suggested that alpha-lipoic acid, magnesium, taurine, coenzyme Q10, and many phytonutrients (such as resveratrol) are also helpful...
September 2014: Journal of Neurosurgical Sciences
https://www.readbyqxmd.com/read/24665660/-renal-risks-of-dietary-complements-a-forgotten-cause
#16
REVIEW
Olympia Dori, Antoine Humbert, Michel Burnier, Daniel Teta
The use of dietary complements like vitamins, minerals, trace elements, proteins, aminoacids and plant-derived agents is prevalent in the general population, in order to promote health and treat diseases. Dietary complements are considered as safe natural products and are easily available without prescription. However, these can lead to severe renal toxicity, especially in cases of unknown pre-existing chronic kidney disease (CKD). In particular, Chinese herbs including aristolochic acid, high doses of vitamine C, creatine and protein complements may lead to acute and chronic renal failure, sometimes irreversible...
February 26, 2014: Revue Médicale Suisse
https://www.readbyqxmd.com/read/24594175/exploitation-of-starch-industry-liquid-by-product-to-produce-bioactive-peptides-from-rice-hydrolyzed-proteins
#17
Lucilla Dei Piu', Annalisa Tassoni, Diana Isabella Serrazanetti, Maura Ferri, Elena Babini, Davide Tagliazucchi, Andrea Gianotti
Small peptides show higher antioxidant capacity than native proteins and may be absorbed in the intestine without further digestion. In our study, a protein by-product from rice starch industry was hydrolyzed with commercial proteolytic enzymes (Alcalase, Neutrase, Flavourzyme) and microbial whole cells of Bacillus spp. and the released peptides were tested for antioxidant activity. Among enzymes, Alcalase was the most performing, while microbial proteolytic activity was less efficient. Conversely, the antioxidant activity was higher in the samples obtained by microbial hydrolysis and particularly with Bacillus pumilus AG1...
July 15, 2014: Food Chemistry
https://www.readbyqxmd.com/read/24281261/advances-in-drug-design-based-on-the-amino-acid-approach-taurine-analogues-for-the-treatment-of-cns-diseases
#18
Man Chin Chung, Pedro Malatesta, Priscila Longhin Bosquesi, Paulo Renato Yamasaki, Jean Leandro Dos Santos, Ednir Oliveira Vizioli
Amino acids are well known to be an important class of compounds for the maintenance of body homeostasis and their deficit, even for the polar neuroactive aminoacids, can be controlled by supplementation. However, for the amino acid taurine (2-aminoethanesulfonic acid) this is not true. Due its special physicochemical properties, taurine is unable to cross the blood-brain barrier. In addition of injured taurine transport systems under pathological conditions, CNS supplementation of taurine is almost null. Taurine is a potent antioxidant and anti-inflammatory semi-essential amino acid extensively involved in neurological activities, acting as neurotrophic factor, binding to GABA A/glycine receptors and blocking the excitotoxicity glutamate-induced pathway leading to be a neuroprotective effect and neuromodulation...
2012: Pharmaceuticals
https://www.readbyqxmd.com/read/24264355/detection-of-sulphur-dioxide-in-the-air-using-scotch-pine-needles
#19
K M Nyomárkay, F Lorand, S János
Air quality is especially important in surface layers, for it is this layer that provides the living components of environment with the needed oxygen and carbon dioxide. Various air polluting gases penetrate cells affecting and contaminating them. Chloroplast shell of some pine species, for instance, doubles under the impact of carbon dioxide which is followed by tillacoids swelling and reduction.Literature provides opinions of some authors, who consider Scotch pine needle to be a biological indicator of sulphur dioxide...
December 1982: Environmental Monitoring and Assessment
https://www.readbyqxmd.com/read/23999674/effect-of-two-different-doses-of-parenteral-amino-acid-supplementation-on-postnatal-growth-of-very-low-birth-weight-neonates-a-randomized-controlled-trial
#20
RANDOMIZED CONTROLLED TRIAL
Haribalakrishna Balasubramanian, Ruchi N Nanavati, Nandkishor S Kabra
OBJECTIVE: To evaluate the effects of two different doses of parenteral aminoacid supplementation on postnatal growth in Very Low Birth Weight (VLBW) infants receiving partial parenteral nutrition (PPN). DESIGN: Double blinded randomized controlled trial. SETTING: Level 3 NICU between February 2008 to February 2010. PARTICIPANTS: 150 inborn babies with birthweight between 900-1250 g, irrespective of gestational age, were randomized to either of the two interventions of amino acid supplementation...
December 2013: Indian Pediatrics
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