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https://www.readbyqxmd.com/read/29233727/a-mathematic-model-and-experimental-verification-of-optimal-nozzle-diameter-in-needle-free-injection
#1
Dongping Zeng, Yong Kang, Lu Xie, Xiaoxiao Xia, Zefeng Wang, Wenchuan Liu
Needle-free injection, as an alternative drug delivery strategy, owns great potential. It is able to reduce complaints about needle phobia and avoid the occurring of accidental needle stick injuries. The nozzle diameter is inherently important in determining the injection dose, injection depth and pain associated with needle-free injections. In this work, needle-free injectors with nozzle diameters of 0.17 mm, 0.20 mm, 0.30 mm, 0.40mm, 0.50 mm were studied in the simulation and experiment. This paper optimizes the mathematical model for spring powered needle-free injection by considering the hydraulic loss due to the abrupt change in the nozzle exit area and the friction force between the piston and ampoule...
December 9, 2017: Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/29230388/blood-body-fluid-exposure-and-needle-stick-sharp-injury-among-nurses-working-in-public-hospitals-southwest-ethiopia
#2
Yeshitila Belay Belachew, Tefera Belachew Lema, Gugssa Nemera Germossa, Yohannes Mehretie Adinew
Background: Every health professional around the world is at risk of blood/body fluid exposure and needle stick/sharp injury as a result of exposure to blood or body fluids and needle or sharp injuries. However, the extent of these hazards and their driving forces are not well documented in Ethiopia. Thus, the aim of this study was to assess determinants of blood/body fluid exposure and needle stick/sharp injury among nurses working in Jimma zone, southwest Ethiopia. Methods: An institution-based census was conducted among 318 nurses working in Jimma zone public hospitals from March 10 to 30, 2016...
2017: Frontiers in Public Health
https://www.readbyqxmd.com/read/29209115/procedure-related-complications-in-gastric-variceal-obturation-with-tissue-glue
#3
Yun-Wei Guo, Hui-Biao Miao, Zhuo-Fu Wen, Jie-Ying Xuan, Hao-Xiong Zhou
AIM: To focus on procedure-related complications, evaluate their incidence, analyze the reasons and discuss the solutions. METHODS: Overall, 628 endoscopic gastric variceal obturation (EGVO) procedures (case-times) with NBC were performed in 519 patients in the Department of Endoscopy of the Third Affiliated Hospital of Sun Yat-Sen University from January 2011 to December 2016. The clinical data of patients and procedure-related complications of EGVO were retrospectively analyzed...
November 21, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/29132876/the-distraction-in-action-tool%C3%A2-feasibility-and-usability-in-clinical-settings
#4
Kirsten Hanrahan, Charmaine Kleiber, Ben J Miller, Heather Davis, Ann Marie McCarthy
PURPOSE: Distraction is a relatively simple, evidence-based intervention to minimize child distress during medical procedures. Timely on-site interventions that instruct parents on distraction coaching are needed. The purpose of this study was to test the feasibility and usability of the Distraction in Action Tool© (DAT©), which 1) predicts child risk for distress with a needle stick and 2) provides individualized instructions for parents on how to be a distraction coach for their child in clinical settings...
November 10, 2017: Journal of Pediatric Nursing
https://www.readbyqxmd.com/read/29129032/needlestick-injuries-among-emergency-medical-services-providers-in-urban-and-rural-areas
#5
Riyadh A Alhazmi, R David Parker, Sijin Wen
Through this study, we assessed the knowledge of EMS providers regarding needle stick injuries (NSIs) and examined differences by demographics. This cross-sectional study used a random sample of certified EMS providers in West Virginia. The survey consists of three sections: socio-demographic characteristics, whether or not got NSIs in the past 12 months, whether or not received needle stick training before. A total of 248 out of 522 (47.31%) EMS providers completed the survey. The majority of EMS providers (81...
November 11, 2017: Journal of Community Health
https://www.readbyqxmd.com/read/29109838/treatment-outcomes-for-isolated-maxillary-complex-fractures-with-maxillomandibular-screws
#6
Rahul Gorka, Amish Jayantilal Gohil, Ashish Kumar Gupta, Santosh Koshy
Intermaxillary fixation (IMF) is a basic and fundamental principle in the management of patients with fractures of the maxillomandibular complex. There are several shortcomings related to the conventionally recommended tooth-mounted devices that are used to achieve IMF. To circumvent these, the use of bone-borne screws has been advocated. We present a series of maxillary fractures treated with IMF screws. Over a 12-month period, 15 cases of maxillary fracture were managed with open reduction and bone plate fixation...
December 2017: Craniomaxillofacial Trauma & Reconstruction
https://www.readbyqxmd.com/read/29109373/development-of-a-lethal-intranasal-exposure-model-of-ebola-virus-in-the-cynomolgus-macaque
#7
Kendra J Alfson, Laura E Avena, Gabriella Worwa, Ricardo Carrion, Anthony Griffiths
Ebola virus (EBOV) is a filovirus that can cause Ebola virus disease (EVD). No approved vaccines or therapies exist for filovirus infections, despite an urgent need. The development and testing of effective countermeasures against EBOV requires use of animal models and a thorough understanding of how the model aligns with EVD in humans. The majority of published studies report outcomes of parenteral exposures for emulating needle stick transmission. However, based on data from EVD outbreaks, close contact exposures to infected bodily fluid seems to be one of the primary routes of EBOV transmission...
October 29, 2017: Viruses
https://www.readbyqxmd.com/read/29106292/preanalytic-factors-associated-with-hemolysis-in-emergency-department-blood-samples
#8
Michael P Phelan, Edmunds Z Reineks, Jesse D Schold, Frederic M Hustey, Janelle Chamberlin, Gary W Procop
CONTEXT: - Hemolysis of emergency department blood samples is a common occurrence and has a negative impact on health care delivery. OBJECTIVES: - To determine the effect of preanalytic factors (straight stick, intravenous [IV] line, needle gauge, location of blood draw, syringe versus vacuum tube use, tourniquet time) on hemolysis in emergency department blood samples. DESIGN: - A single 65 000-visit emergency department's electronic health record was queried for emergency department potassium results and blood draw technique for all samples obtained in calendar year 2014, resulting in 54 531 potassium results...
November 6, 2017: Archives of Pathology & Laboratory Medicine
https://www.readbyqxmd.com/read/29074440/microarray-patches-potentially-useful-delivery-systems-for-long-acting-nanosuspensions
#9
REVIEW
Ryan F Donnelly, Eneko Larrañeta
Long-acting drug nanosuspension formulations are coming to the fore as controlled release strategies for several medical conditions and as a preventative measure against HIV infection. However, such delivery systems must, by necessity, be given by hypodermic injection, typically into muscle. This poses problems for patients who are needle-phobic, given that injections have to be administered on a weekly or monthly basis. Needle-stick injuries, inappropriate reuse of needles, and poor disposal practices are major challenges in developing countries...
October 23, 2017: Drug Discovery Today
https://www.readbyqxmd.com/read/29074201/safety-acceptability-and-tolerability-of-uncoated-and-excipient-coated-high-density-silicon-micro-projection-array-patches-in-human-subjects
#10
Paul Griffin, Suzanne Elliott, Kenia Krauer, Cristyn Davies, S Rachel Skinner, Christopher D Anderson, Angus Forster
Most vaccinations are performed by intramuscular injection with a needle and syringe. However, this method is not ideal due to limitations, such as the risk of needle-stick injury, the requirement for trained personnel to give injections and the need to reconstitute lyophilized vaccines. Therefore, we tested an alternative delivery technology that overcomes the problems with needle and syringe. The Nanopatch™ is an array of 10,000 silicon micro-projections per cm(2) that can be dry-coated with vaccine for skin delivery...
October 23, 2017: Vaccine
https://www.readbyqxmd.com/read/29071987/-clinical-research-on-double-needle-winding-and-pulling-combined-with-electroacupuncture-therapy-in-treating-scapulohumeral-periarthritis
#11
Ning Wang, Xiao-Ping Wu, Peng-Jie Sheng
OBJECTIVE: To observe the efficacy of double-needle winding and pulling combined with electroacupuncture in treating scapulohumeral periarthritis. METHODS: Sixty cases with scapulohumeral periarthritis were equally randomized into treatment group and control group (n=30 in each group). Jianliao (TE 14), Jianyu(LI 15), Naoshu(SI 10), Jianzhen(SI 9), Binao(LI 14), Quyuan(SI 13), Quchi(LI 11), Shousanli(LI 10) were selected in the two groups. In the treatment group,double-needles were inserted respectively into TE 14,LI 15 and SI 10, twirling till sticking,then the needles were pulled for 3 times...
June 25, 2017: Zhen Ci Yan Jiu, Acupuncture Research
https://www.readbyqxmd.com/read/29044068/needle-stick-injuries-in-a-tertiary-eye-care-hospital-incidence-management-outcomes-and-recommendations
#12
Ekta Rishi, B Shantha, Abhinav Dhami, Pukhraj Rishi, Hannah C Rajapriya
PURPOSE: The purpose of this study is to assess the incidence, management, and outcomes for needle stick injuries (NSIs) in a tertiary eye-care hospital and provide appropriate recommendations for its prevention. METHODS: This was a retrospective database review of NSI recorded between 2010 and 2015 at a tertiary eye care center. All staff members who had NSI were managed with standard treatment protocol. The mode, location, health-care workers affected and/or at risk for NSI were analyzed...
October 2017: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/29028422/enterococcus-faecalis-endophthalmitis-in-children-a-21-year-study
#13
Ekta Rishi, Pukhraj Rishi, Pramod Bhende, Rajiv Raman, Parveen Sen, Pradeep Susvar, Chetan Rao, Lily Therese, Rajshri Hirawat
PURPOSE: To report Enterococcus faecalis endophthalmitis (EFE) in children and its comparison with adults. METHODS: Retrospective study of 19 children up to 18 years age, undergoing vitrectomy for EFE at a referral eye center from January 1995 to December 2015. The results were compared to 18 adults with EFE. RESULTS: The mean age was 7.4 ± 3.06 years. Post-traumatic EFE was seen in 17 (89.4%) children (p < 0.05) versus postoperative EFE seen in 12 (66%) adults...
October 13, 2017: Ocular Immunology and Inflammation
https://www.readbyqxmd.com/read/29017610/hiv-among-people-who-inject-drugs-in-hungary
#14
András Ortutay, V Anna Gyarmathy, Zsuzsa Marjanek, Károly Nagy, József Rácz, István Barcs
BACKGROUND: Before 2014 (the year of closure of the two largest needle exchange programs in Hungary, which halved the number of available syringes in the country despite increased injecting risk practices) no HIV was reportedly acquired in Hungary among people who inject drugs (PWIDs) who were not also men who had sex with other men (MSM). In 2014, one and in 2015 two non-MSM PWIDs were newly diagnosed with HIV who supposedly became infected in Hungary, and both incident HIV cases in 2015 were diagnosed in the AIDS stage...
October 11, 2017: Infectious Diseases of Poverty
https://www.readbyqxmd.com/read/28987894/students-nurses-knowledge-and-prevalence-of-needle-stick-injury-in-jordan
#15
Mohammad Suliman, Mohammad Al Qadire, Manar Alazzam, Sami Aloush, Arwa Alsaraireh, Faris A Alsaraireh
BACKGROUND: Student nurses are at high risk of blood-borne pathogens transmitted via Needle Stick Injury (NSI). Understanding various aspects of NSI is essential if they are to avoid the risks associated with it. OBJECTIVES: The study was conducted to measure student nurses' level of knowledge about NSI and to examine its prevalence and post-exposure measures in Jordan. DESIGN: A cross-sectional and descriptive design was used. SAMPLE AND SETTING: A sample of 279 student nurses studying at one private and four government universities distributed throughout Jordan...
October 1, 2017: Nurse Education Today
https://www.readbyqxmd.com/read/28948854/in-vitro-evaluation-of-archaeosome-vehicles-for-transdermal-vaccine-delivery
#16
Yimei Jia, Michael J McCluskie, Dongling Zhang, Robert Monette, Umar Iqbal, Maria Moreno, Janelle Sauvageau, Dean Williams, Lise Deschatelets, Zygmunt J Jakubek, Lakshmi Krishnan
Archaeosomes composed of archaeal total polar lipids (TPL) or semi-synthetic analog vesicles have been used as vaccine adjuvants and delivery systems in animal models for many years. Typically administered by intramuscular or subcutaneous injections, archaeosomes can induce robust, long-lasting humoral and cell-mediated immune responses against entrapped antigens and provide protection in murine models of infectious disease and cancer. Herein, we evaluated various archaeosomes for transdermal delivery, since this route may help eliminate needle-stick injuries and needle re-use, and therefore increase patient compliance...
September 26, 2017: Journal of Liposome Research
https://www.readbyqxmd.com/read/28913514/the-incidence-of-needle-stick-and-sharp-injuries-and-their-associations-with-visual-function-among-hospital-nurses
#17
Mohammad Ghasemi, Mehdi Khabazkhoob, Hassan Hashemi, Abbasali Yekta, Payam Nabovati
PURPOSE: To determine the one-year incidence of needle stick and sharp injuries (NSIs and SIs) and their associations with visual function among Iranian nurses. METHODS: In this cross-sectional study, 278 nurses working at one hospital were selected through stratified random sampling. After applying the exclusion criteria, the final analysis was performed on the data of 267 nurses. The data of occupational injuries were collected through a researcher-administered questionnaire...
September 2017: Journal of Current Ophthalmology
https://www.readbyqxmd.com/read/28904259/prevalence-and-risk-factors-of-needle-stick-and-sharp-injury-among-tertiary-hospital-workers-vientiane-lao-pdr
#18
Chieko Matsubara, Kayako Sakisaka, Vanphanom Sychareun, Alongkone Phensavanh, Moazzam Ali
ObjectivesHealth care workers (HCWs) face risks of needle stick and sharp injuries (NSIs). Most NSIs occur in developing countries, however, no epidemiological study on NSIs is publicly available in Lao PDR. The objective of this study is to identify the prevalence and risk factors of NSIs among HCWs in Lao PDR.MethodsThis cross-sectional study was designed to determine the prevalence and risk factors of NSIs among four tertiary hospitals in Vientiane, Lao People's Democratic Republic.ResultsSix months before the survey, 11...
September 13, 2017: Journal of Occupational Health
https://www.readbyqxmd.com/read/28890905/single-versus-multiple-site-harvesting-techniques-for-bone-marrow-concentrate-evaluation-of-aspirate-quality-and-pain
#19
Kristin Oliver, Tariq Awan, Matthew Bayes
BACKGROUND: Bone marrow concentrate (BMC) is growing in popularity as an alternative treatment option in orthopaedics. The regenerative capacity of BMC has been linked to the number of mesenchymal stem cells (MSCs) present in the graft at the time of its clinical application. MSC counts in bone marrow aspirate (BMA) are affected by harvest technique, but controversy exists over which aspiration method optimizes cellular yield while taking patient comfort and risk into consideration. PURPOSE: To compare a single- versus multiple-site bone marrow aspiration technique to determine which would generate a sufficient volume of high-quality BMA for concentration into a BMC graft...
August 2017: Orthopaedic Journal of Sports Medicine
https://www.readbyqxmd.com/read/28855920/occupational-exposure-to-needle-stick-and-sharp-injuries-and-associated-factors-among-health-care-workers-in-awi-zone-amhara-regional-state-northwest-ethiopia-2016
#20
Abebe Dilie, Desalegn Amare, Tenaw Gualu
BACKGROUND: Needle stick and sharp injuries were one of the major risk factors for blood and body fluid borne infections at health care facilities. OBJECTIVE: To assess occupational exposure to needle stick and sharp injuries and associated factors among health care workers in Awi zone, 2016. METHODS: institutional based cross-sectional study was conducted among 193 health care workers. Study participants were selected using systematic random sampling technique...
2017: Journal of Environmental and Public Health
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