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https://www.readbyqxmd.com/read/29790447/data-driven-process-to-improve-va-surgical-flow
#1
Balmatee Bidassie, William Gunnar, Leigh Starr, George Van Buskirk, Lisa Warner, Clifford Anckaitis, Angela Howard
Purpose During years 2014-2016, Veterans Health Administration National Surgery Office conducted a surgical flow improvement initiative (SFII) to assist low-performing surgery programs to improve their operating room efficiency (ORE). The initiative was co-sponsored by VHA National Surgery Office and VHA Office of Systems Redesign and Improvement. The paper aims to discuss this issue. Design/methodology/approach An SFII algorithm, based on first-time-start (FTS), cancellation rate (CR), lag time (LT) and OR utilization, assigned an ORE performance Level (1-low to 4-high) to each VA Medical Center (VAMC)...
May 14, 2018: International Journal of Health Care Quality Assurance
https://www.readbyqxmd.com/read/29764613/the-joint-use-of-resilience-engineering-and-lean-production-for-work-system-design-a-study-in-healthcare
#2
Caroline Brum Rosso, Tarcisio Abreu Saurin
Although lean production (LP) has been increasingly adopted in healthcare systems, its benefits often fall short of expectations. This might be partially due to the failure of lean to account for the complexity of healthcare. This paper discusses the joint use of principles of LP and resilience engineering (RE), which is an approach for system design inspired by complexity science. Thus, a framework for supporting the design of socio-technical systems, which combines insights from LP and RE, was developed and tested in a system involving a patient flow from an emergency department to an intensive care unit...
September 2018: Applied Ergonomics
https://www.readbyqxmd.com/read/29755850/three-dimensional-printing-and-cell-therapy-for-wound-repair
#3
REVIEW
Sylvia van Kogelenberg, Zhilian Yue, Jeremy N Dinoro, Christopher S Baker, Gordon G Wallace
Significance: Skin tissue damage is a major challenge and a burden on healthcare systems, from burns and other trauma to diabetes and vascular disease. Although the biological complexities are relatively well understood, appropriate repair mechanisms are scarce. Three-dimensional bioprinting is a layer-based approach to regenerative medicine, whereby cells and cell-based materials can be dispensed in fine spatial arrangements to mimic native tissue. Recent Advances: Various bioprinting techniques have been employed in wound repair-based skin tissue engineering, from laser-induced forward transfer to extrusion-based methods, and with the investigation of the benefits and shortcomings of each, with emphasis on biological compatibility and cell proliferation, migration, and vitality...
May 1, 2018: Advances in Wound Care
https://www.readbyqxmd.com/read/29746916/an-effective-neural-model-extracting-document-level-chemical-induced-disease-relations-from-biomedical-literature
#4
Wei Zheng, Hongfei Lin, Zhiheng Li, Xiaoxia Liu, Zhengguang Li, Bo Xu, Yijia Zhang, Zhihao Yang, Jian Wang
Since identifying relations between chemicals and diseases (CDR) are important for biomedical research and healthcare, the challenge proposed by BioCreative V requires automatically mining causal relationships between chemicals and diseases which may span sentence boundaries. Although most systems explore feature engineering and knowledge bases to recognize document level CDR relations, feature learning automatically is limited only in a sentence. In this work, we proposed an effective model that automatically learns document level semantic representations to extract chemical-induced disease (CID) relations from articles by combining advantages of convolutional neural network and recurrent neural network...
May 7, 2018: Journal of Biomedical Informatics
https://www.readbyqxmd.com/read/29744423/3d-additive-manufactured-nanocomposite-magnetic-scaffolds-effect-of-the-application-mode-of-a-time-dependent-magnetic-field-on-hmscs-behavior
#5
Ugo D'Amora, Teresa Russo, Antonio Gloria, Virginia Rivieccio, Vincenzo D'Antò, Giacomo Negri, Luigi Ambrosio, Roberto De Santis
Over the past few years, the influence of static or dynamic magnetic fields on biological systems has become a topic of considerable interest. Magnetism has recently been implicated to play significant roles in the regulation of cell responses and, for this reason, it is revolutionizing many aspects of healthcare, also suggesting new opportunities in tissue engineering. The aim of the present study was to analyze the effect of the application mode of a time-dependent magnetic field on the behavior of human mesenchymal stem cells (hMSCs) seeded on 3D additive-manufactured poly(ɛ-caprolactone)/iron-doped hydroxyapatite (PCL/FeHA) nanocomposite scaffolds...
September 2017: Bioactive Materials
https://www.readbyqxmd.com/read/29743083/policy-environment-for-prevention-control-and-management-of-cardiovascular-diseases-in-primary-health-care-in-kenya
#6
Gershim Asiki, Shuai Shao, Carol Wainana, Christopher Khayeka-Wandabwa, Tilahun N Haregu, Pamela A Juma, Shukri Mohammed, David Wambui, Enying Gong, Lijing L Yan, Catherine Kyobutungi
BACKGROUND: In Kenya, cardiovascular diseases (CVDs) accounted for more than 10% of total deaths and 4% of total Disability-Adjusted Life Years (DALYs) in 2015 with a steady increase over the past decade. The main objective of this paper was to review the existing policies and their content in relation to prevention, control and management of CVDs at primary health care (PHC) level in Kenya. METHODS: A targeted document search in Google engine using keywords "Kenya national policy on cardiovascular diseases" and "Kenya national policy on non-communicable diseases (NCDs)" was conducted in addition to key informant interviews with Kenyan policy makers...
May 9, 2018: BMC Health Services Research
https://www.readbyqxmd.com/read/29737418/towards-a-clinical-trial-protocol-to-evaluate-health-information-systems-evaluation-of-a-computerized-system-for-monitoring-tuberculosis-from-a-patient-perspective-in-brazil
#7
Nathalia Yukie Crepaldi, Inacia Bezerra de Lima, Fernanda Bergamini Vicentine, Lídia Maria Lourençon Rodrigues, Tiago Lara Michelin Sanches, Antonio Ruffino-Netto, Domingos Alves, Rui Pedro Charters Lopes Rijo
Assessment of health information systems consider different aspects of the system itself. They focus or on the professional who will use the software or on its usability or on the software engineering metrics or on financial and managerial issues. The existent approaches are very resources consuming, disconnected, and not standardized. As the software becomes more critical in the health organizations and in patients, becoming used as a medical device or a medicine, there is an urgency to identify tools and methods that can be applied in the development process...
May 8, 2018: Journal of Medical Systems
https://www.readbyqxmd.com/read/29736579/combination-of-polymeric-supports-and-drug-delivery-systems-for-osteochondral-regeneration
#8
Luis Rojo
Musculoskeletal conditions have been defined by European National Health systems as one of the key themes which should be featured during the present decade as a consequence of the significant healthcare and social support costs. Among others, articular cartilage degeneration due to traumatic and degenerative lesion injury or other pathologies commonly results in the development of musculoskeletal disorders such as osteoarthritis and arthritis rheumatoid, eventually leading to progressive articular cartilage and joint destruction especially at osteochondral interphase, that account for more disability among the elderly than any other diseases constituting a global social challenge that needs a multidisciplinary response from the scientific community...
2018: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/29733891/-connecting-worlds-a-view-on-microfluidics-for-a-wider-application
#9
REVIEW
Ana C Fernandes, Krist V Gernaey, Ulrich Krühne
From its birth, microfluidics has been referenced as a revolutionary technology and the solution to long standing technological and sociological issues, such as detection of dilute compounds and personalized healthcare. Microfluidics has for example been envisioned as: (1) being capable of miniaturizing industrial production plants, thereby increasing their automation and operational safety at low cost; (2) being able to identify rare diseases by running bioanalytics directly on the patient's skin; (3) allowing health diagnostics in point-of-care sites through cheap lab-on-a-chip devices...
May 4, 2018: Biotechnology Advances
https://www.readbyqxmd.com/read/29731951/advanced-computational-methods-in-bio-mechanics
#10
REVIEW
Waleed M S Al Qahtani, Mohamed I El-Anwar
A novel partnership between surgeons and machines, made possible by advances in computing and engineering technology, could overcome many of the limitations of traditional surgery. By extending surgeons' ability to plan and carry out surgical interventions more accurately and with fewer traumas, computer-integrated surgery (CIS) systems could help to improve clinical outcomes and the efficiency of healthcare delivery. CIS systems could have a similar impact on surgery to that long since realised in computer-integrated manufacturing...
April 15, 2018: Open Access Macedonian Journal of Medical Sciences
https://www.readbyqxmd.com/read/29726299/in-vivo-immunogenicity-of-bovine-bone-removed-by-a-novel-decellularization-protocol-based-on-supercritical-carbon-dioxide
#11
Ling You, Xu Weikang, Yang Lifeng, Liang Changyan, Lin Yongliang, Wei Xiaohui, Xu Bin
Trauma or infections associated critical bone defects lead to a huge economic burden in the healthcare system worldwide. Recent advances in tissue engineering have led to potential new strategies for the repair, replacement, and regeneration of bone defects, especially in biomaterials and decellularization protocols from xenogenic tissues. However, the complexity in bone structure and mechanical environment limits the synthesis of artificial bone with biomaterials. Thus, the purpose of our study is to develop a natural bone scaffold with great immunocompatibility...
May 4, 2018: Artificial Cells, Nanomedicine, and Biotechnology
https://www.readbyqxmd.com/read/29707389/making-ward-based-outreach-teams-an-effective-component-of-human-immunodeficiency-virus-programmes-in-south-africa
#12
Nireshni Naidoo, Jean Railton, Geoffrey Jobson, Nthabiseng Matlakala, Gert Marincowitz, James A McIntyre, Helen E Struthers, Remco P H Peters
The implementation of ward-based outreach teams (WBOTs), comprised of community health workers (CHWs), is one of the three interventions of the South African National Department of Health's (NDoH) Primary Health Care (PHC) Re-engineering strategy for improving health outcomes. CHWs provide a necessary structure to contribute to successful implementation of the human immunodeficiency virus (HIV) programme in four ways: (1) prevention of HIV infection by health education, (2) linkage to care by health education and referrals, (3) adherence support and (4) identification of individuals who are failing treatment...
2018: Southern African Journal of HIV Medicine
https://www.readbyqxmd.com/read/29707260/can-composite-digital-monitoring-biomarkers-come-of-age-a-framework-for-utilization
#13
REVIEW
Christopher Kovalchick, Rhea Sirkar, Oliver B Regele, Lampros C Kourtis, Marie Schiller, Howard Wolpert, Rhett G Alden, Graham B Jones, Justin M Wright
Introduction: The application of digital monitoring biomarkers in health, wellness and disease management is reviewed. Harnessing the near limitless capacity of these approaches in the managed healthcare continuum will benefit from a systems-based architecture which presents data quality, quantity, and ease of capture within a decision-making dashboard. Methods: A framework was developed which stratifies key components and advances the concept of contextualized biomarkers...
December 2017: Journal of Clinical and Translational Science
https://www.readbyqxmd.com/read/29698598/sequentially-moldable-and-bondable-4d-hydrogels-compatible-with-cell-encapsulation
#14
Mariana B Oliveira, Henrique X S Bastos, João F Mano
Hydrogels have captivated the attention of several research and industry segments, including bioengineering, tissue engineering, implantable/wearable sensors and actuators, bioactive agent delivery, food processing, and industrial processes optimization. A common limitation of these systems is their fixed shape. The concept of hydrogel moldability is often assigned to the injectability potential of liquid precursors, and this feature is often lost right after hydrogel formation. Hydrogel modulation is a recent trend that advocates the importance of designing materials with shape fitting ability targeting on-demand responses or defect filling purposes...
April 26, 2018: Biomacromolecules
https://www.readbyqxmd.com/read/29695248/use-of-the-self-organising-map-network-somnet-as-a-decision-support-system-for-regional-mental-health-planning
#15
Younjin Chung, Luis Salvador-Carulla, José A Salinas-Pérez, Jose J Uriarte-Uriarte, Alvaro Iruin-Sanz, Carlos R García-Alonso
BACKGROUND: Decision-making in mental health systems should be supported by the evidence-informed knowledge transfer of data. Since mental health systems are inherently complex, involving interactions between its structures, processes and outcomes, decision support systems (DSS) need to be developed using advanced computational methods and visual tools to allow full system analysis, whilst incorporating domain experts in the analysis process. In this study, we use a DSS model developed for interactive data mining and domain expert collaboration in the analysis of complex mental health systems to improve system knowledge and evidence-informed policy planning...
April 25, 2018: Health Research Policy and Systems
https://www.readbyqxmd.com/read/29681432/a-systematic-review-evaluating-the-role-of-nurses-and-processes-for-delivering-early-mobility-interventions-in-the-intensive-care-unit
#16
REVIEW
Anna Krupp, Linsey Steege, Barbara King
OBJECTIVES: To investigate processes for delivering early mobility interventions in adult intensive care unit patients used in research and quality improvement studies and the role of nurses in early mobility interventions. METHODS: A systematic review was conducted. Electronic databases PubMED, CINAHL, PEDro, and Cochrane were searched for studies published from 2000 to June 2017 that implemented an early mobility intervention in adult intensive care units. Included studies involved progression to ambulation as a component of the intervention, included the role of the nurse in preparing for or delivering the intervention, and reported at least one patient or organisational outcome measure...
April 19, 2018: Intensive & Critical Care Nursing: the Official Journal of the British Association of Critical Care Nurses
https://www.readbyqxmd.com/read/29626550/drug-delivery-systems-and-materials-for-wound-healing-applications
#17
Saghi Saghazadeh, Chiara Rinoldi, Maik Schot, Sara Saheb Kashaf, Fatemeh Sharifi, Elmira Jalilian, Kristo Nuutila, Giorgio Giatsidis, Pooria Mostafalu, Hossein Derakhshandeh, Kan Yue, Wojciech Swieszkowski, Adnan Memic, Ali Tamayol, Ali Khademhosseini
Chronic, non-healing wounds place a significant burden on patients and healthcare systems, resulting in impaired mobility, limb amputation, or even death. Chronic wounds result from a disruption in the highly orchestrated cascade of events involved in wound closure. Significant advances in our understanding of the pathophysiology of chronic wounds have resulted in the development of drugs designed to target different aspects of the impaired processes. However, the hostility of the wound environment rich in degradative enzymes and its elevated pH, combined with differences in the time scales of different physiological processes involved in tissue regeneration require the use of effective drug delivery systems...
April 4, 2018: Advanced Drug Delivery Reviews
https://www.readbyqxmd.com/read/29522497/stem-cells-and-engineered-scaffolds-for-regenerative-wound-healing
#18
REVIEW
Biraja C Dash, Zhenzhen Xu, Lawrence Lin, Andrew Koo, Sifon Ndon, Francois Berthiaume, Alan Dardik, Henry Hsia
The normal wound healing process involves a well-organized cascade of biological pathways and any failure in this process leads to wounds becoming chronic. Non-healing wounds are a burden on healthcare systems and set to increase with aging population and growing incidences of obesity and diabetes. Stem cell-based therapies have the potential to heal chronic wounds but have so far seen little success in the clinic. Current research has been focused on using polymeric biomaterial systems that can act as a niche for these stem cells to improve their survival and paracrine activity that would eventually promote wound healing...
March 9, 2018: Bioengineering
https://www.readbyqxmd.com/read/29445626/catastrophic-health-expenditure-in-iran-a-review-article
#19
REVIEW
Aidin Aryankhesal, Manal Etemadi, Mohammad Mohseni, Saber Azami-Aghdash, Majid Nakhaei
Background: One of the main challenges of healthcare systems is to protect people from consequences of health expenditures. Such expenditures may lead to catastrophic financial loss in families so that many people deny demanding necessary healthcare services, which results in harms to their health status. The aim of this systematic review was to investigate the catastrophic health expenditures trend and its related factors in Iran. Methods: This systematic review and meta-analysis was conducted on studies conducted between 1984 and 2014...
February 2018: Iranian Journal of Public Health
https://www.readbyqxmd.com/read/29445505/the-japanese-clinical-practice-guidelines-for-management-of-sepsis-and-septic-shock-2016-j-sscg-2016
#20
Osamu Nishida, Hiroshi Ogura, Moritoki Egi, Seitaro Fujishima, Yoshiro Hayashi, Toshiaki Iba, Hitoshi Imaizumi, Shigeaki Inoue, Yasuyuki Kakihana, Joji Kotani, Shigeki Kushimoto, Yoshiki Masuda, Naoyuki Matsuda, Asako Matsushima, Taka-Aki Nakada, Satoshi Nakagawa, Shin Nunomiya, Tomohito Sadahiro, Nobuaki Shime, Tomoaki Yatabe, Yoshitaka Hara, Kei Hayashida, Yutaka Kondo, Yuka Sumi, Hideto Yasuda, Kazuyoshi Aoyama, Takeo Azuhata, Kent Doi, Matsuyuki Doi, Naoyuki Fujimura, Ryota Fuke, Tatsuma Fukuda, Koji Goto, Ryuichi Hasegawa, Satoru Hashimoto, Junji Hatakeyama, Mineji Hayakawa, Toru Hifumi, Naoki Higashibeppu, Katsuki Hirai, Tomoya Hirose, Kentaro Ide, Yasuo Kaizuka, Tomomichi Kan'o, Tatsuya Kawasaki, Hiromitsu Kuroda, Akihisa Matsuda, Shotaro Matsumoto, Masaharu Nagae, Mutsuo Onodera, Tetsu Ohnuma, Kiyohiro Oshima, Nobuyuki Saito, So Sakamoto, Masaaki Sakuraya, Mikio Sasano, Norio Sato, Atsushi Sawamura, Kentaro Shimizu, Kunihiro Shirai, Tetsuhiro Takei, Muneyuki Takeuchi, Kohei Takimoto, Takumi Taniguchi, Hiroomi Tatsumi, Ryosuke Tsuruta, Naoya Yama, Kazuma Yamakawa, Chizuru Yamashita, Kazuto Yamashita, Takeshi Yoshida, Hiroshi Tanaka, Shigeto Oda
Background and Purpose: The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock 2016 (J-SSCG 2016), a Japanese-specific set of clinical practice guidelines for sepsis and septic shock created jointly by the Japanese Society of Intensive Care Medicine and the Japanese Association for Acute Medicine, was first released in February 2017 in Japanese. An English-language version of these guidelines was created based on the contents of the original Japanese-language version...
January 2018: Acute Medicine & Surgery
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