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https://www.readbyqxmd.com/read/28064052/development-of-novel-carboxymethyl-cellulose-k-carrageenan-blends-as-an-enteric-delivery-vehicle-for-probiotic-bacteria
#1
Alireza Dafe, Hossein Etemadi, Habib Zarredar, Gholam Reza Mahdavinia
This study reports a novel carrier based on blends of carboxymethyl cellulose (CMC) and k-Carrageenan (k-Carr) for probiotic colon delivery. Lactobacillus plantarum ATCC:13643 (L. plantarum) cells were encapsulated in CMC/k-Carr blends by extrusion method. k-carrageenan was used as a coating agent to improve encapsulation of L. plantarum cells in carboxymethyl cellulose biopolymer. K-Carrageenan and carboxymethyl cellulose were ionically cross-linked with K(+) and Ca(2+) ions, respectively. Optical and scanning electron microscopy obviously showed the random distribution of L...
January 4, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28056966/pseudorabies-virus-infection-aujeszky-s-disease-in-an-iberian-lynx-lynx-pardinus-in-spain-a-case-report
#2
A Javier Masot, María Gil, David Risco, Olga M Jiménez, José I Núñez, Eloy Redondo
BACKGROUND: The only natural hosts of Pseudorabies virus (PRV) are members of the family Suidae (Sus scrofa scrofa). In species other than suids infection is normally fatal. In these mammals, including carnivores, PRV typically causes serious neurologic disease. The endangered Iberian lynx (Lynx pardinus) is a wild feline endemic to south-western Europe (Iberian Peninsula). The Iberian lynx was found to be the world's most endangered felid species in 2002. In wild felines, PRV infection has only been previously reported once in a Florida panther in 1994...
January 5, 2017: BMC Veterinary Research
https://www.readbyqxmd.com/read/28044953/a-rare-case-of-upper-digestive-hemorrhage-due-to-bleeding-duodenal-tumor
#3
Claudiu Turculeţ, Dragoş Ene, Teodor Florin Georgescu, E Ciucă, A Vlădăşcău, Florin Iordache, Mircea Beuran
We present the case of a 48-year-old patient with no medical history, who presents himself to the emergency room with melena, asthenia and dizziness. The blood tests revealed a severe anemia (Hb = 4,8 g/dL). He is admitted in the Gastroenterology ward, where a first superior digestive endoscopy is performed which shows a duodenal bleeding tumor (second duodenum) of 7 cm in length. After the administration of red blood cell mass, plasma and haemostatic agents the level of the hemoglobin increases. The abdominal CT scan reveals a 3/5 tumor localized in the second and third duodenum...
November 2016: Chirurgia
https://www.readbyqxmd.com/read/28029082/probiotics-in-curing-allergic-and-inflammatory-conditions-research-progress-and-futuristic-vision
#4
Kuldeep Dhama, Shyma K Latheef, Ashok Kumar Munjal, Rekha Khandia, Hari Abdul Samad, Hafiz M N Iqbal, Sunil K Joshi
BACKGROUND: Probiotics constitute the viable and beneficial microbes, which offer a dietary means to sustain the balance of gastro-intestinal (GI) microflora. Owing to their multiple health benefits, these have recently gained wide attention among researchers for exploring their potential in safeguarding the health of humans and animals. Probiotics could also modulate host-immune responses, thereby help in counteracting the immunological dysfunctions. Probiotics can inhibit the systemic invasion of pathogens entering through the GI mucosa/ oral cavity and have been found to possess effective prophylactic and therapeutic utilities against various infectious pathogens as well as non-infectious diseases and disorders...
December 26, 2016: Recent Patents on Inflammation & Allergy Drug Discovery
https://www.readbyqxmd.com/read/28024457/haemorrhagic-enteritis-of-turkeys-current-knowledge
#5
Kuldeep Dhama, Vasudevan Gowthaman, Kumaragurubaran Karthik, Ruchi Tiwari, Swati Sachan, M Asok Kumar, M Palanivelu, Yashpal Singh Malik, Raj Kumar Singh, Muhammad Munir
Haemorrhagic enteritis virus (HEV), an adenovirus associated with acute hemorrhagic gastro-intestinal disease of 6-11 weeks old turkeys predominantly hampers both humoral and cellular immunity. Affected birds are more prone to secondary complications (like colibacillosis and clostridiosis) and failure to mount an effective vaccine-induced immune response. HEV belongs to the new genus Siadenovirus. Feco-oral transmission is the main route of entry of the virus and it mainly colonizes bursa, intestine and spleen...
December 27, 2016: Veterinary Quarterly
https://www.readbyqxmd.com/read/28018095/gastrointestinal-neuromuscular-apparatus-an-underestimated-target-of-gut-microbiota
#6
EDITORIAL
Michele Pier Luca Guarino, Michele Cicala, Lorenza Putignani, Carola Severi
Over the last few years, the importance of the resident intestinal microbiota in the pathogenesis of several gastro-intestinal diseases has been largely investigated. Growing evidence suggest that microbiota can influence gastro-intestinal motility. The current working hypothesis is that dysbiosis-driven mucosal alterations induce the production of several inflammatory/immune mediators which affect gut neuro-muscular functions. Besides these indirect mucosal-mediated effects, the present review highlights that recent evidence suggests that microbiota can directly affect enteric nerves and smooth muscle cells functions through its metabolic products or bacterial molecular components translocated from the intestinal lumen...
December 7, 2016: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/27857647/nutrition-chez-le-br%C3%A3-l%C3%A3
#7
G Perro
Nutrition is a challenge for burn patients. Emphasized points are early enteral amounts by means of a naso-gastric tube, semi-recumbent position > 30°, gastro-intestinal survey improved by kinetics, weight evolution, nutritional amounts assessment to prevent proteino-energetic deficiency. Feeding is difficult with children, as with seniors often associating a preexisting starvation. Nutritional supplements are useful in medium severity patients. For overweight patients, hypo caloric and hyperprotidic diet is the better choice...
March 31, 2016: Annals of Burns and Fire Disasters
https://www.readbyqxmd.com/read/27836310/effects-of-perioperative-supplementation-with-pro-synbiotics-on-clinical-outcomes-in-surgical-patients-a-meta-analysis-with-trial-sequential-analysis-of-randomized-controlled-trials
#8
Xiang-Dong Wu, Meng-Meng Liu, Xi Liang, Ning Hu, Wei Huang
BACKGROUND & AIMS: The Potential benefits and possible risks of perioperative supplementation with probiotics/synbiotics in surgical patients are not fully understood. Recent evidence has rapidly evolved and conveys conflicting results. Thus, we undertook a meta-analysis of randomized controlled trials (RCTs) to valuate the effectiveness, safety, cost-effectiveness and quality of life of perioperative supplementation with pro-/synbiotics. METHODS: We systematically searched PubMed, Embase and the Cochrane Library through October 2015 to identify RCTs that assessed the effects of perioperative supplementation with pro-/synbiotics in surgical patients...
October 26, 2016: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/27821030/prognostic-scores-in-acute-pancreatitis-a-review
#9
REVIEW
Z Balcı, M Ö Kılıç, K Şenol, A Erdoğan, M Tez
Predicting the course of an attack of acute pancreatitis still represents a challenge for the physicians.Some early interventions such as endoscopic retrograde cholangiopancreatography and sphincterotomy, admission to the intensive care unit, enteral feeding, and prophylactic antibiotics have been proven to decrease morbidity and mortality in patients of high-risk groups. However, acute pancreatitis has a potential of morbidity and mortality, and therefore early diagnosis and objective assessment of severity of the disease is fundamental...
July 2016: Acta Gastro-enterologica Belgica
https://www.readbyqxmd.com/read/27821025/adult-intussusception-10-year-experience-in-two-belgian-centres
#10
F de Clerck, E Vanderstraeten, M De Vos, C Van Steenkiste
BACKGROUND: adult intussusception is a rare entity with a different clinical presentation and aetiology than in children. Objective: To provide a comprehensive overview of the clinical presentation, aetiology, diagnosis and management of adult intussusception. METHODS: We review 43 cases with a preoperative diagnosis of symptomatic gastrointestinal adult intussusception. RESULTS: In 67% of the cases an underlying lead point was discovered...
July 2016: Acta Gastro-enterologica Belgica
https://www.readbyqxmd.com/read/27682832/rett-syndrome-a-wide-clinical-and-autonomic-picture
#11
G Pini, S Bigoni, L Congiu, A M Romanelli, M F Scusa, P Di Marco, A Benincasa, P Morescalchi, A Ferlini, F Bianchi, D Tropea, M Zappella
BACKGROUND: Rett Syndrome is a neurodevelopmental disorder almost exclusively affecting females, characterized by a broad clinical spectrum of signs and symptoms and a peculiar course. The disease affects different body systems: nervous, muscolo-skeletal, gastro-enteric. Moreover, part of the symptoms are related to the involvement of the autonomic nervous system. In the Tuscany Rett Center at Versilia Hospital, we collected data from 151 subjects with a clinical diagnosis of classical or variant RTT syndrome...
September 29, 2016: Orphanet Journal of Rare Diseases
https://www.readbyqxmd.com/read/27671836/two-hourly-versus-3-hourly-feeding-for-very-low-birthweight-infants-a-randomised-controlled-trial
#12
Nor Rosidah Ibrahim, Tan Hooi Kheng, Ariffin Nasir, Noraida Ramli, Jimmy Lee Kok Foo, Sharifah Huda Syed Alwi, Hans Van Rostenberghe
OBJECTIVE: To determine whether feeding with 2-hourly or 3-hourly feeding interval reduces the time to achieve full enteral feeding and to compare their outcome in very low birthweight preterm infants. DESIGN: Parallel-group randomised controlled trial with a 1:1 allocation ratio. SETTING: Two regional tertiary neonatal intensive care units. PATIENTS: 150 preterm infants less than 35 weeks gestation with birth weight between 1...
September 26, 2016: Archives of Disease in Childhood. Fetal and Neonatal Edition
https://www.readbyqxmd.com/read/27554826/gastrointestinal-tract-obstruction-secondary-to-post-operative-oedema-does-dexamethasone-administration-help
#13
M Atie, O Khoma, G Dunn, G L Falk
Oedema can occur in handled tissues following upper gastrointestinal surgery with anastomosis formation. Obstruction of the lumen may result in delayed return of enteric function. Intravenous steroid use may be beneficial. Three cases of delayed emptying following fundoplication, gastro-enteric and entero-enteric anastomoses are reviewed. Conservative management with supportive measures failed. Dexamethasone was administered to treat the oedematous obstruction. A literature review in PubMed, Cochrane database and Medline for English language publications on the use of dexamethasone in the treatment of acute post surgical oedema of the upper gastrointestinal was conducted...
2016: Journal of Surgical Case Reports
https://www.readbyqxmd.com/read/27554294/intestinal-tuft-cells-epithelial-sentinels-linking-luminal-cues-to-the-immune-system
#14
F Gerbe, P Jay
Epithelial tuft cells (also known as "brush" cells in the airway) were first identified morphologically, almost six decades ago in the trachea and gastro-intestinal tract, but their function remained mysterious until three almost simultaneous reports recently revealed their essential role in the initiation of immune type 2 responses. This is a new and exciting example of cooperation between the epithelial and haematopoietic compartments for the management of enteric parasite infections. Here we review tuft cell functions and markers, and anchors epithelial tuft cells within the current paradigm of type 2 immune responses...
November 2016: Mucosal Immunology
https://www.readbyqxmd.com/read/27491544/expression-of-cystic-fibrosis-transmembrane-conductance-regulator-in-ganglia-of-human-gastrointestinal-tract
#15
Ruiqi Xue, Huan Gu, Yamei Qiu, Yong Guo, Christine Korteweg, Jin Huang, Jiang Gu
CF is caused by mutations of the gene encoding the cystic fibrosis transmembrane conductance regulator (CFTR) which is an anion selective transmembrane ion channel that mainly regulates chloride transport, expressed in the epithelia of various organs. Recently, we have demonstrated CFTR expression in the brain, the spinal cord and the sympathetic ganglia. This study aims to investigate the expression and distribution of CFTR in the ganglia of the human gastrointestinal tract. Fresh tissue and formalin-fixed paraffin-embedded normal gastrointestinal tract samples were collected from eleven surgical patients and five autopsy cases...
2016: Scientific Reports
https://www.readbyqxmd.com/read/27486522/percutaneous-endoscopic-transgastric-jejunostomy-peg-j-a-retrospective-analysis-on-its-utility-in-maintaining-enteral-nutrition-after-unsuccessful-gastric-feeding
#16
Ezekiel Wong Toh Yoon, Kaori Yoneda, Shinya Nakamura, Kazuki Nishihara
BACKGROUND/AIMS: Although percutaneous endoscopic gastrostomy (PEG) is the method of choice for long-term enteral nutrition, feeding-related adverse events such as aspiration pneumonia and peristomal leakage can impede the use of PEG. Percutaneous endoscopic transgastric jejunostomy (PEG-J) using large-bore jejunal tubes may help by circumventing gastric passage during enteral nutrition and improving drainage of gastric secretions. METHODS: 20 patients (12 males and 8 females) who received PEG-J after unsuccessful PEG feeding during a 6-year period in our institution were analysed retrospectively to evaluate the efficacy of large-bore jejunal feeding tubes in maintaining enteral nutrition...
2016: BMJ Open Gastroenterology
https://www.readbyqxmd.com/read/27414125/role-of-stereotactic-body-radiation-therapy-with-volumetric-modulated-arcs-and-high-intensity-photon-beams-for-the-treatment-of-abdomino-pelvic-lymph-node-metastases
#17
Ciro Franzese, Luca Cozzi, Davide Franceschini, Giuseppe D'Agostino, Tiziana Comito, Fiorenza De Rose, Pierina Navarria, Pietro Mancosu, Stefano Tomatis, Antonella Fogliata, Marta Scorsetti
AIM: To study clinical outcome for oligometastatic patients (abdominal lymph-node metastases) treated with stereotactic body radiation therapy. MATERIALS AND METHODS: Seventy-one patients were studied retrospectively. Dose prescription was 45 Gy in six fractions. Clinical outcome was assessed with actuarial analysis. RESULTS: The median follow-up was 1.5 years; 45 patients (63.3%) had solitary metastasis, and 26 (36.6%) had multiple lesions...
August 8, 2016: Cancer Investigation
https://www.readbyqxmd.com/read/27397730/gastrointestinal-and-nutritional-problems-in%C3%A2-neurologically-impaired-children
#18
REVIEW
Paolo Quitadamo, Nikhil Thapar, Annamaria Staiano, Osvaldo Borrelli
The current increasing survival of children with severe central nervous system damage has created a major challenge for medical care. Gastrointestinal and nutritional problems in neurologically impaired children have been recently recognized as an integral part of their disease, often leading to growth failure and worsened quality of life for both children and caregivers. Nutritional support is essential for the optimal care of these children. Undernourished handicapped children might not respond properly to intercurrent diseases and suffer unnecessarily...
November 2016: European Journal of Paediatric Neurology: EJPN
https://www.readbyqxmd.com/read/27380396/analysis-occurrence-fate-and-risks-of-proton-pump-inhibitors-their-metabolites-and-transformation-products-in-aquatic-environment-a-review
#19
Christina I Kosma, Dimitra A Lambropoulou, Triantafyllos A Albanis
Proton pump inhibitors (PPIs) which include omeprazole, esomeprazole, lansoprazole, pantoprazole and rabeprazole, are extensively used for the relief of gastro-intestinal disorders. Despite their high worldwide consumption, PPIs are extensively metabolized in human bodies and therefore are not regularly detected in monitoring studies. Very recently, however, it has been shown that some omeprazole metabolites may enter and are likely to persist in aquatic environment. Hence, to fully assess the environmental exposures and risks associated with PPIs, it is important to better understand and evaluate the fate and behavior not only of the parent compound but also of their metabolites and their transformation products arising from biotic and abiotic processes (hydrolysis, photodegradation, biodegradation etc...
November 1, 2016: Science of the Total Environment
https://www.readbyqxmd.com/read/27344948/hepato-and-gastro-protective-activity-of-purified-oat-1-3-1-4-%C3%AE-d-glucans-of-different-molecular-weight
#20
Dominika Suchecka, Joanna Harasym, Jacek Wilczak, Joanna Gromadzka-Ostrowska
Protective and antioxidant properties of highly purified oat β-glucans of high and low molecular weight in liver and stomach were evaluated. The novelty in approach was to determine whether dietary β-glucans affect the parameters of oxidative stress directly in the stomach and indirectly in the liver, especially in inflammation states. Physicochemical properties e.g. viscoelastic was found as strictly dependent from molecular weight of oat β-glucans hence its metabolic activity could also show dependence...
October 2016: International Journal of Biological Macromolecules
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