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https://www.readbyqxmd.com/read/28329078/apical-closure-device-for-full-percutaneous-transapical-valve-implantation-stress-test-in-an-animal-model%C3%A2
#1
Enrico Ferrari, Stefanos Demertzis, Jennifer Angelella, Denis Berdajs, Piergiorgio Tozzi, Tiziano Moccetti, Francesco Maisano, Ludwig K von Segesser
OBJECTIVES: Transapical valve implantation is traditionally performed through a left antero-lateral mini-thoracotomy. A self-expandable apical closure device has recently been developed for full-percutaneous transapical valve implantation. We performed haemodynamics stress-tests on an animal model to evaluate the sealing properties. METHODS: Under general anaesthesia 5 pigs (mean weight: 67 ± 6 Kg) received full heparinization (100 IU/Kg; activated clotting time >250 s and, through inferior mini-sternotomies, 21-Fr introducer sheaths for transapical aortic valve implantation (outer diameter: 25-Fr) were placed over-the-wire in the apexes...
January 31, 2017: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/28321296/improving-surgical-and-anaesthesia-practice-review-of-the-use-of-the-who-safe-surgery-checklist-in-felege-hiwot-referral-hospital-ethiopia
#2
Ryan Ellis, Ahmad Izzuddin Mohamad Nor, Iona Pimentil, Zebenaye Bitew, Jolene Moore
Development of surgical and anaesthetic care globally has been consistently reported as being inadequate. The Lancet Commission on Global Surgery highlights the need for action to address this deficit. One such action to improve global surgical safety is the introduction of the WHO Surgical Checklist to Operating Rooms (OR) around the world. The checklist has a growing body of evidence supporting its ability to assist in the delivery of safe anaesthesia and surgical care. Here we report the introduction of the Checklist to a major Ethiopian referral hospital and low-resource setting and highlight the success and challenges of its implementation over a one year period...
2017: BMJ Quality Improvement Reports
https://www.readbyqxmd.com/read/28320917/predictors-of-massive-blood-transfusion-a-delphi-study-to-examine-the-views-of-experts
#3
Jacqueline V Mclennan, K C Mackway-Jones, S T Horne, R Body
BACKGROUND: Trauma patients requiring massive blood transfusion (MBT) have high morbidity and mortality: early and aggressive use of blood products during immediate resuscitation may improve survival. There is currently a lack of evidence to guide initial identification of these patients which is especially important in areas where plasma may need to be thawed. In the absence of this evidence, this study aimed to robustly evaluate expert opinion by using a Delphi process to identify predictors of massive transfusion...
March 20, 2017: Journal of the Royal Army Medical Corps
https://www.readbyqxmd.com/read/28319126/effects-of-sevoflurane-and-clonidine-on-acid-base-status-and-long-term-emotional-and-cognitive-outcomes-in-spontaneously-breathing-rat-pups
#4
Nicole Almenrader, Paola Colucci, Valentina De Castro, Daniela Valeri, Maura Palmery, Viviana Trezza, Patrizia Campolongo
BACKGROUND: Numerous experiments in rodents suggest a causative link between exposure to general anaesthetics during brain growth spurt and poor long-lasting neurological outcomes. Many of these studies have been questioned with regard of their translational value, mainly because of extremely long anaesthesia exposure. Therefore, the aim of the present study was to assess the impact of a short sevoflurane anaesthesia, alone or combined with clonidine treatment, on respiratory function in spontaneously breathing rat pups and overall effects on long-lasting emotional and cognitive functions...
2017: PloS One
https://www.readbyqxmd.com/read/28316083/energy-metabolism-in-the-rat-cortex-under-thiopental-anaesthesia-measured-in-vivo-by-13-c-mrs
#5
Sarah Sonnay, João M N Duarte, Nathalie Just, Rolf Gruetter
Barbiturates, commonly used as general anaesthetics, depress neuronal activity and thus cerebral metabolism. Moreover, they are likely to disrupt the metabolic support of astrocytes to neurons, as well as the uptake of nutrients from circulation. By employing (13) C magnetic resonance spectroscopy (MRS) in vivo at high magnetic field, we characterized neuronal and astrocytic pathways of energy metabolism in the rat cortex under thiopental anaesthesia. The neuronal tricarboxylic acid (TCA) cycle rate was 0.46 ± 0...
March 19, 2017: Journal of Neuroscience Research
https://www.readbyqxmd.com/read/28315922/superior-perioperative-analgesia-with-combined-femoral-obturator-sciatic-nerve-block-in-comparison-with-posterior-lumbar-plexus-and-sciatic-nerve-block-for-acl-reconstructive-surgery
#6
Metaxia Bareka, Michael Hantes, Eleni Arnaoutoglou, George Vretzakis
PURPOSE: The purpose of this randomized controlled study is to compare and evaluate the intraoperative and post-operative outcome of PLPS nerve block and that of femoral, obturator and sciatic (FOS) nerve block as a method of anaesthesia, in performing ACL reconstruction. METHODS: Patients referred for elective arthroscopic ACL reconstruction using hamstring autograft were divided in two groups. The first group received combined femoral-obturator-sciatic nerve block (FOS Group) under dual guidance, whereas the second group received posterior lumbar plexus block under neurostimulation and sciatic nerve block (PLPS Group) under dual guidance...
March 18, 2017: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/28306591/ventilation-with-high-versus-low-peep-levels-during-general-anaesthesia-for-open-abdominal-surgery-does-not-affect-postoperative-spirometry-a-randomised-clinical-trial
#7
Tanja A Treschan, Maximilian Schaefer, Johann Kemper, Bea Bastin, Peter Kienbaum, Benedikt Pannen, Sabrine N Hemmes, Marcelo G de Abreu, Paolo Pelosi, Marcus J Schultz
BACKGROUND: Invasive mechanical ventilation during general anaesthesia for surgery typically causes atelectasis and impairs postoperative lung function. OBJECTIVE: We investigated the effect of intraoperative ventilation with high positive end-expiratory pressure (PEEP) and recruitment manoeuvres (RMs) on postoperative spirometry. DESIGN: This was a preplanned, single-centre substudy of an international multicentre randomised controlled trial, the PROVHILO trial...
March 16, 2017: European Journal of Anaesthesiology
https://www.readbyqxmd.com/read/28302244/disseminated-intravascular-coagulation-developing-after-cranioplasty
#8
Wenming Wang, Hua Liu, Jian Yang, Yafang Shen
Disseminated intravascular coagulation (DIC) developing after cranioplasty, a skull reconstructive surgical procedure, is very rare. The presently reported patient underwent cranioplasty for cranial trauma under general anaesthesia using titanium prostheses. Her laboratory data was unremarkable. She underwent three operations, each complicated by excessive postoperative bleeding. Although the patient received massive blood transfusions, but no cryoprecipitate coagulum was given during the first two re-operations, and excessive bleeding was evident...
March 2017: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
https://www.readbyqxmd.com/read/28299763/the-efficacy-of-transrectal-ultrasound-guided-biopsy-versus-transperineal-template-biopsy-of-the-prostate-in-diagnosing-prostate-cancer-in-men-with-previous-negative-transrectal-ultrasound-guided-biopsy
#9
Shady Nafie, Michael Wanis, Masood Khan
PURPOSE: We have previously demonstrated that transperineal template prostate biopsy (TPTPB) has a significantly higher cancer detection rate compared to transrectal ultrasound guided (TRUS) biopsy in biopsy naive men with a PSA < 20 ng/mL. We, therefore, performed a prospective study to determine whether TPTPB is still superior to TRUS biopsy in the detection of prostate cancer in men with persistently elevated PSA after one previous negative set of TRUS biopsies. MATERIALS AND METHODS: 42 patients with a background of one previous negative set of TRUS biopsy, persistently elevated PSA (but < 20 ng/mL) and benign feeling digital rectal examination (DRE) underwent simultaneous standard 12-core TRUS biopsy and 36-core TPTPB under general anaesthesia...
March 16, 2017: Urology Journal
https://www.readbyqxmd.com/read/28298792/comparison-of-king-vision-and-truview-laryngoscope-for-postextubation-visualization-of-vocal-cord-mobility-in-patients-undergoing-thyroid-and-major-neck-surgeries-a-randomized-clinical-trial
#10
Anto Sahaya Priyanka, Kusha Nag, V R Hemanth Kumar, Dewan Roshan Singh, Senthil Kumar, T Sivashanmugam
BACKGROUND: Visualization of vocal cords following extubation after thyroid and major neck surgeries is highly desirable for the surgeon as well as the anaesthesiologist to rule out vocal cord palsy or oedema. As the patient is emerging from general anaesthesia, it may be challenging for the anaesthesiologist to optimally visualise and grade vocal cord movement following extubation. SETTING: Randomized clinical trial at a tertiary care centre. METHODOLOGY: After obtaining institutional ethics committee approval, 60 patients posted for thyroid and major neck surgeries under American Society of Anesthesiologists (ASA) grade I and II were recruited for the study...
January 2017: Anesthesia, Essays and Researches
https://www.readbyqxmd.com/read/28298758/comparison-of-analgesic-efficacy-of-dexmedetomidine-and-midazolam-as-adjuncts-to-lignocaine-for-intravenous-regional-anesthesia
#11
Bharti Gupta, Ravinder Kumar Verma, Sudershan Kumar, Geeta Chaudhary
BACKGROUND: Intravenous regional anesthesia (IVRA) is safe, technically simple, and cost-effective technique compared to general anesthesia with success rates of 94-98% for upper and lower limb surgeries. The main disadvantage of this procedure is its limited duration for surgery, lack of postoperative analgesia, and tourniquet pain. To overcome this disadvantage, various adjuvants to lignocaine have been studied from time to time. AIM: To compare the analgesic efficacy of dexmedetomidine and midazolam as adjuncts to lignocaine for IVRA for forearm and hand surgeries...
January 2017: Anesthesia, Essays and Researches
https://www.readbyqxmd.com/read/28298751/comparative-study-of-two-laryngeal-mask-airways-proseal-laryngeal-mask-airway-and-supreme-laryngeal-mask-airway-in-anesthetized-paralyzed-adults-undergoing-elective-surgery
#12
Ravneet Kaur Gill, Abhijit Tarat, Debagopal Pathak, Suneeta Dutta
CONTEXT: Supraglottic airway devices can act as an alternative to endotracheal intubation in both normal and difficult airway. LMA Proseal (P-LMA) and LMA Supreme (S-LMA) alongwith acting as effective ventilating device, provide port for gastric drainage. AIM: The objective of this study was to compare the two devices for effective ventilation and complications. SETTING AND DESIGN: A prospective, randomized, single-blinded study was conducted in a tertiary care teaching hospital...
January 2017: Anesthesia, Essays and Researches
https://www.readbyqxmd.com/read/28296244/-watchful-observation-follow-up-scheme-after-endoscopic-co2-laser-treatment-for-small-glottic-carcinomas-a-retrospective-study-of-93-cases
#13
Patrice Gallet, Cécile Rumeau, Duc Trung Nguyen, Pedro Augusto Teixeira, Cédric Baumann, Bruno Toussaint
OBJECTIVES: Evaluate the clinical outcome of patients treated with CO2-laser surgery for early-stage glottic carcinomas followed-up with 3 month laryngoscopy regardless of tumor grade and margins. DESIGN: Case series. SETTING: Retrospective review of the clinical records of patients treated at the ENT department of a tertiary university hospital. PARTICIPANTS AND METHOD: Clinical records from patients with early-stage glottic carcinomas (Tis-T2) treated with curative intent by CO2-laser surgery in a ten year period were evaluated...
March 10, 2017: Clinical Otolaryngology
https://www.readbyqxmd.com/read/28295465/quantification-of-piritramide-in-human-colostrum
#14
A Van Eeckhaut, P Vanfleteren, J Van Schoors, Y Van Wanseele, J Poelaert, Y Michotte
WHAT IS KNOWN AND OBJECTIVE: In our university hospital (UZBrussel), one of the options to control post-operative pain after a Caesarean section under general anaesthesia is to administer piritramide by patient-controlled intravenous analgesia (PCIA). As no information is available about the possible transfer of this synthetic narcotic analgesic into breastmilk, women are frequently advised not to breastfeed their newborn. A sensitive liquid chromatographic (LC) method coupled with UV detection will therefore be developed and validated for the quantification of piritramide in colostrum samples to evaluate the presence of the analgesic in the first milk...
March 13, 2017: Journal of Clinical Pharmacy and Therapeutics
https://www.readbyqxmd.com/read/28294672/-the-history-of-outpatients-surgery-in-transylvania
#15
Árpád Péterffy, Pál Péterffy Jun, Pál Péterffy
The authors reported 291 outpatient general surgical interventions performed during a 10-year period (1948-1957). All surgeries were scheduled and performed in local anaesthesia with bend of 0.5% novocain and 0.5‰ percain solutions. The type of surgery was abdominal wall surgery in 68 cases, intraabdominal (mainly appendectomy, gastric resection and cholecystectomy) in 144 cases, anorectal in 50 cases, urogenital in 10 cases, thyroid in 12 cases and other interventions in seven cases. There was neither surgical mortality nor complications which needed hospitalisation...
March 2017: Magyar Sebészet
https://www.readbyqxmd.com/read/28293789/development-of-an-ovine-model-for-training-in-vaginal-surgery-for-pelvic-organ-prolapse
#16
A Mansoor, S Curinier, S Campagne-Loiseau, L Platteeuw, B Jacquetin, B Rabischong
INTRODUCTION AND HYPOTHESIS: This aim of this study was to evaluate the feasibility and usefulness of an ovine model for training in vaginal surgery. METHODS: Four senior urogynaecological surgeons and five residents attended five sessions of vaginal surgery for pelvic organ prolapse (POP) in five old multiparous female sheep. Urogynaecological examinations were performed and measurements similar to the POP-Q classification in humans were obtained. Standard POP surgical procedures with and without mesh were performed...
March 14, 2017: International Urogynecology Journal
https://www.readbyqxmd.com/read/28292390/penile-incarceration-by-metallic-ring
#17
(no author information available yet)
Application of constricting objects over penis for auto-erotic purpose can lead to dangerous results. A variety of metallic and non-metallic objects are used. The removal of these objects is a great challenge. We report a case of a young man who placed a hard metallic ring around his penis for sexual pleasure. A 22-year old man presented in emergency department with complain of painful swelling of his penis since 4 hours. Physical examination revealed part of penis distal to ring as congested and markedly tender with decreased sensation...
February 2017: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
https://www.readbyqxmd.com/read/28289667/laparoscopic-cholecystectomy-under-spinal-epidural-anesthesia-vs-general-anaesthesia-a-prospective-randomised-study
#18
Turgut Donmez, Vuslat Muslu Erdem, Sinan Uzman, Dogan Yildirim, Huseyin Avaroglu, Sina Ferahman, Oguzhan Sunamak
PURPOSE: Laparoscopic cholecystectomy (LC) is usually performed under the general anesthesia (GA). Aim of the study is to investigate the availability, safety and side effects of combined spinal/epidural anesthesia (CSEA) and comparison it with GA for LC. METHODS: Forty-nine patients who have a LC plan were included into the study. The patients were randomly divided into GA (n = 25) and CSEA (n = 24) groups. Intraoperative and postoperative adverse events, postoperative pain levels were compared between groups...
March 2017: Annals of Surgical Treatment and Research
https://www.readbyqxmd.com/read/28283552/anaesthetic-considerations-for-surgery-in-newborns
#19
Constance S Houck, Amy E Vinson
Almost 30 years ago, the American Academy of Pediatrics Committee on Fetus and Newborn coauthored a policy statement strongly advocating for the use of anaesthesia in all neonates stating 'local or systemic pharmacologic agents now available permit relatively safe administration of anesthesia or analgesia to neonates undergoing surgical procedures and that such administration is indicated according to the usual guidelines for the administration of anesthesia to high-risk, potentially unstable patients'. With current techniques and advanced monitoring, preterm and full-term infants routinely undergo surgical procedures under general anaesthesia to repair congenital defects that were lethal in years past...
March 10, 2017: Archives of Disease in Childhood. Fetal and Neonatal Edition
https://www.readbyqxmd.com/read/28281629/is-the-current-usage-of-dental-general-anaesthetic-appropriate
#20
J S Lau
Ten years on: Is dental general anaesthesia in childhood a risk factor for caries and anxiety?
March 10, 2017: British Dental Journal
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